The strong vertical discontinuities pose a fundamental challenge to optimizing stimulated reservoir volume(SRV)in multilayered reservoirs.This research proposes a radial borehole-assisted horizontal well fracturing te...The strong vertical discontinuities pose a fundamental challenge to optimizing stimulated reservoir volume(SRV)in multilayered reservoirs.This research proposes a radial borehole-assisted horizontal well fracturing technology,which is expected to achieve effective vertical stimulation and commingled production across multiple pay zones.Under different geological and engineering conditions,the vertical propagation behavior of hydraulic fractures guided by radial boreholes can be determined by adjusting the interlayered lithologies and radial borehole configurations in experimental samples.Experimental results reveal four fracture network patterns:passivated,cross-layer,skip-layer,and hybrid fractures in the radial borehole fracturing.The radial boreholes perform better fracture guiding performances in the high-brittleness interlayers,which form cross-layer and hybrid fracture networks to improve the growth height.Hydraulic fractures tend to propagate from high-strength to low-strength layers under radial borehole guidance.When radial boreholes interconnect multiple lithology layers,hydraulic fractures initiate preferentially in lower-strength zones rather than remaining confined to borehole root ends.Increased radial borehole length and diameter facilitate fracture skip-layer initiation and cross-layer propagation,while multiple borehole branches enhance fracture penetration across high-strength interlayers.Radial boreholes with inclination angles below 30°enhance fracture height by generating cross-layer and hybrid fracture networks.Furthermore,an inter-borehole phase angle of less than 180°facilitates single-wing fracture cross-layer propagation.Fracture height is primarily governed by radial borehole length,followed by quantity,inclination angle,and diameter.Based on the geometric similarity criteria,the recommended parameters for radial borehole-assisted fracturing in a 5 1/2-inch horizontal well include a length>15 m,an inclination angle<30°,and a diameter>52 mm to ensure effective stimulation across three or more pay zones.Finally,the field-scale numerical model was developed to simulate the optimized radial borehole fracturing and demonstrate the technical superiority.These findings are expected to provide an in-depth understanding of the effective stimulation in multilayered reservoirs.展开更多
Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the m...Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.展开更多
AIM:To describe the technique and the outcomes of manual Bowman layer and stroma transplant-onlay(BLST-o)for 2 cases of radial keratotomy(RK).METHODS:Two patients with visual fluctuations and corneal irregularity due ...AIM:To describe the technique and the outcomes of manual Bowman layer and stroma transplant-onlay(BLST-o)for 2 cases of radial keratotomy(RK).METHODS:Two patients with visual fluctuations and corneal irregularity due to RK were offered manual BLST-o as an alternative to penetrating keratoplasty(PKP).Visual acuity,refraction,corneal topography,corneal aberrometry,and corneal optical coherence tomography(OCT)pre-and postoperative were analyzed.Histology was obtained for 1 case.RESULTS:Both patients had corneal anatomical and morphological improvement,with elimination of the visual fluctuations.In one case,a subsequent excimer laser treatment improved corneal shape further,thus improving vision.The other case,whereas initially improved,developed epithelial ingrowth following suture removal.The latter was explanted and had a xenogeneic implant.The explanted sample was sent for histology,showing a viable graft of Bowman layer and anterior stroma.CONCLUSION:Manual BLST-o is a potential option for the management of symptoms post RK.These grafts may facilitate subsequent treatments such as laser corrections,and may not preclude from other interventions after explantation.展开更多
The number and diversity of inhibitory neurons(INs)increased substantially during mammalian brain evolution.However,the generative mechanisms of the vast repertoire of human INs remain elusive.We performed spatial and...The number and diversity of inhibitory neurons(INs)increased substantially during mammalian brain evolution.However,the generative mechanisms of the vast repertoire of human INs remain elusive.We performed spatial and single-cell transcriptomics of human medial ganglionic eminence(hMGE),a pivotal source of cortical and subpallial INs,and built the trajectories of hMGE-derived cells during brain development.We identified spatiotemporally and molecularly segregated progenitor cell populations fated to produce distinct IN types.展开更多
Transradial access (TRA) has emerged as the preferred vascular access route forcoronary angiography and percutaneous coronary interventions due to itssuperior safety profile compared to transfemoral access. However, i...Transradial access (TRA) has emerged as the preferred vascular access route forcoronary angiography and percutaneous coronary interventions due to itssuperior safety profile compared to transfemoral access. However, its widespreadadoption raises concerns regarding structural alterations in the radial artery,which may impact long-term vascular health and future procedural feasibility.TRA is associated with histopathologic changes in the arterial wall, such asintimal injury and hyperplasia, medial remodeling and adventitial inflammation,collectively contributing to radial artery remodeling. Moreover, TRA can inducechanges in radial artery lumen diameter driven by an inflammatory response dueto arterial puncture and mechanical friction during the procedure. Nonetheless, amore clinically significant consequence is radial artery occlusion, which is influencedby various procedural and patient-related factors. Strategies to minimizeremodeling include meticulous pre-procedural ultrasound assessment to ensureappropriate sheath-to-artery size matching, periprocedural pharmacologicalinterventions and implementation of patent hemostasis techniques. This reviewsynthesizes current knowledge regarding the mechanisms, clinical implications,and preventive strategies related to radial artery remodeling following TRA. Further research is needed toelucidate the long-term consequences of radial artery remodeling and to refine preventive strategies for preservingradial artery patency and its suitability for future interventions.展开更多
Radial head(RH)arthroplasty(RHA)has emerged as a critical intervention in the management of complex elbow fractures,particularly Mason type III and IV injuries where the native RH is irreparable.Beyond its role in pai...Radial head(RH)arthroplasty(RHA)has emerged as a critical intervention in the management of complex elbow fractures,particularly Mason type III and IV injuries where the native RH is irreparable.Beyond its role in pain relief and joint congruity,RHA serves as a biomechanical cornerstone for restoring the lateral column and ensuring elbow stability,especially in the presence of associated ligamentous injuries or fracture-dislocations.This editorial synthesizes current evidence on RHA in Mason type III and IV RH fractures,with attention to biomechanical rationale,implant design,and complication trends.Aiming to reaffirm RHA’s position as a vital tool in contemporary elbow trauma care,a simplified treatment algorithm is presented to support individualized surgical decisionmaking.展开更多
BACKGROUND Radial head fractures constitute approximately one-third of all elbow fractures,significantly impacting the young and active population.While open reduction and internal fixation is the preferred treatment ...BACKGROUND Radial head fractures constitute approximately one-third of all elbow fractures,significantly impacting the young and active population.While open reduction and internal fixation is the preferred treatment for displaced fractures,its high complication rate in comminuted fractures has led to the increasing use of radial head arthroplasty(RHA).RHA provides improved functional outcomes with fewer complications,yet its long-term efficacy remains a topic of debate.AIM To evaluate the functional outcomes of patients undergoing RHA with a modular metallic prosthesis for comminuted Mason type III and IV radial head fractures.METHODS A prospective and retrospective hospital-based study was conducted at Dayanand Medical College and Hospital,Ludhiana over 32 months(January 2021-August 2023).A total of 26 patients with Mason type III and IV fractures were included,with six retrospective and 20 prospective cases.Functional outcomes were assessed using the Mayo Elbow Performance Score(MEPS),elbow range of motion,pain via Visual Analog Scale,and activities of daily living at immediate postoperative,three-month,and six-month follow-ups.RESULTS MEPS at 6 months follow up for 4 cases(15.38%)had good scores,and 22 cases(84.62%)had excellent scores,with a mean±SD of 97.31±6.67.Comparisons showed significant improvement from immediate post-operative to 3 months(P<0.0001),from immediate post-operative to 6 months(P<0.0001),and between 3 months and 6 months(P<0.0001).None of the patients had elbow instability after radial head replacement and 22 cases(84.62%)had no complications,while 3 cases(11.54%)had a stiff elbow,and 1 case(3.85%)had heterotopic ossification.CONCLUSION RHA is an effective treatment for comminuted radial head fractures,providing stable elbow function with minimal complications.展开更多
Medium-high maturity continental shale oil is one of the hydrocarbon resources with the most potential for successful development in China.Nevertheless,the unique geological conditions of a multi-lithologic superposit...Medium-high maturity continental shale oil is one of the hydrocarbon resources with the most potential for successful development in China.Nevertheless,the unique geological conditions of a multi-lithologic superposition shield the vertical propagation of hydraulic fractures and limit the longitudinal reconstruction in reservoirs,posing a great challenge for large-scale volumetric fracturing.Radial wellbore crosslayer fracturing,which transforms the interaction between the hydraulic fractures and lithologic interface into longitudinal multilayer competitive initiation,could provide a potential solution for this engineering challenge.To determine the longitudinal propagation behaviors of fractures guided by radial wellbores,true triaxial fracturing experiments were performed on multilayer shale-sandstone samples,with a focus on the injection pressure response,fracture morphology,and cross-layer pattern.The effects of the radial borehole length L,vertical stress difference K_(v),injection rate Q,and viscosity m of the fracturing fluid were analyzed.The results indicate that radial wellbores can greatly facilitate fracture initiation and cross-layer propagation.Unlike conventional hydraulic fracturing,there are two distinct fracture propagation patterns in radial wellbore fracturing:cross-layering and skip-layering.The fracture height guided by a radial wellbore is positively correlated with K_(v),Q,and m.Increasing these parameters causes a shift in the fracture initiation from a single root to an asynchronous root/toe end and can improve the cross-layer propagation capacity.Critical parameter thresholds exist for fracture propagation through and across interlayers under the guidance of radial boreholes.A parameter combination of critical cross-layering/skip-layering or alternating displacement/viscosity is recommended to simultaneously improve the fracture height and degree of lateral activation.The degree of correlation of different parameters with the vertical fracture height can be written as L>Q/m>K_(v).Increasing the radial wellbore length can effectively facilitate fracture cross-/skip-layer propagation and reduce the critical threshold of injection parameters,which is conducive to maximizing the stimulated reservoir volume.展开更多
This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junctio...This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junction solar cells represent a major advancement in photovoltaic technologies, as they optimize light absorption and charge collection efficiency. The focus is on the impact of the magnetic field and temperature on the decay of transient voltage, which provides crucial information on recombination processes and the lifetime of minority carriers. The results reveal that the magnetic field tends to increase the transient voltage by directly affecting the transient electron density. Indeed, for B > 7 × 10−5 T, the magnetic field prolongs the relaxation time by increasing the transient voltage amplitude. Additionally, rising temperatures accelerate (ranging from 290 K to 450 K) recombination processes, thereby reducing the transient voltage, although this effect is moderated by the presence of a magnetic field. The study highlights the complex interaction between magnetic field and temperature, with significant impacts on the transient behaviour.展开更多
This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity fa...This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity factor (LSF), genetic algorithms (GA) methods, and numerical method based on LSF. The methodology aims to determine the optimal allocation and sizing of multiple PV-DG to minimize power loss through time series power flow analysis. An approach utilizing continuous sensitivity analysis is developed and inherently leverages power flow and loss equations to compute LSF of all buses in the system towards employing a dynamic PV-DG model for more accurate results. The algorithm uses a numerical grid search method to optimize PV-DG placement in a power distribution system, focusing on minimizing system losses. It combines iterative analysis, sensitivity assessment, and comprehensive visualization to identify and present the optimal PV-DG configurations. The present-ed algorithms are verified through co-simulation framework combining MATLAB and OpenDSS to carry out analysis for 12-bus radial distribution test system. The proposed numerical method is compared with other algorithms, such as ELF, LSF methods, and Genetic Algorithms (GA). Results show that the proposed numerical method performs well in comparison with LSF and ELF solutions.展开更多
Radial growth of trees is highly sensitive to environmental changes,but the effect of climate on tree rings in Qinghai spruce(Picea crassifolia),a widely distributed endemic conifer in western China,is more complex th...Radial growth of trees is highly sensitive to environmental changes,but the effect of climate on tree rings in Qinghai spruce(Picea crassifolia),a widely distributed endemic conifer in western China,is more complex than in many other conifers.A comprehensive understanding of the spatiotemporal climatic responses of its rings is needed to develop theoretical basis for designing strategies for its conservation and management.Here,our synthesis of the literature on responses of radial growth of Qinghai spruce to monthly climate variables in different environmental conditions by meta-analysis showed that precipitation and drought severity are the main limiting factors for Qinghai spruce radial growth in the semiarid region of northwestern China.In warmer and drier areas,radial growth of Qinghai spruce is mainly limited by drought.In the areas north of the 600-mm annual precipitation isoline,the tree-ring width(TRW)was significantly positively correlated with precipitation and significantly negatively correlated with temperature during the growing season(June-August).The limiting effect of drought on Qinghai spruce is also gradually increasing from southeast to northwest,to the west of 103°E and within 37°N-39°N.展开更多
An experimental study of the diffusive mass transfer between a droplet and an oscillating immiscible liquid in a horizontal axisymmetricHele-Shaw cell is carried out.Theliquid oscillates radially in the cell.Thetransv...An experimental study of the diffusive mass transfer between a droplet and an oscillating immiscible liquid in a horizontal axisymmetricHele-Shaw cell is carried out.Theliquid oscillates radially in the cell.Thetransverse size of the droplet exceeds the cell thickness.The viscosities of the droplet and the surrounding liquid are comparable.Relevant effort is provided to design and test an experimental setup and validate a protocol for determining the mass transfer rate of a solute in a two-liquid system.In particular,fluorescent dye Rhodamine B is considered as the solute.A critical comparison of the situations with and without oscillation is implemented.A procedure is introduced and validated to determine the molecular and effective diffusion coefficients through evaluation of the growth of the diffusion zone width over time.It is shown that,in the presence of the liquid oscillations,there is a significant increase in the width of the zone in which Rhodamine B is present compared to the reference case with no oscillations.The oscillatory flow leads to an intensification of the solute diffusion due to intense time-averaged flows inside the droplet and the surrounding liquid and oscillations of the drop itself.Thestudy is of significant practical interest with particular relevance to typical processes for liquid-liquid extraction.展开更多
Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of...Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of Xiaowutai Mountain,four Chinese pine(Pinus tabulaeformis)ring-width index chronologies were established at different elevations(1290–1600 m).Species growth trends were estimated using climate change projections derived from global climate models.The results show:(1)the four ring-width chronologies exhibited strong statistical characteristics,making them suitable for dendroclimatology studies.Radial growth-climate relationships were highly consistent,showing a negative correlation with previous September temperatures and current May–June temperatures,as well as a positively correlated with precipitation and Palmer Drought Severity Index during the corresponding period;and(2)climate change scenarios revealed that temperature will gradually increase on the Xiaowutai Mountain,and only a slight variation in precipitation is expected.Chinese pine radial growth may show a decline under future climate change.展开更多
The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study...The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study clarifies the relationship between radial pressure and bonding length for the ultimate pullout force and reveals the microscopic failure process of the resin-rock interface in the anchoring system.The results show that the ultimate load increases with the increase of bonding length in three different stages:rapid,slow,and uniform growth.The new mechanical model developed considering radial pressure describes the inverse relationship between radial pressure and the plastic zone on the bonding section,and quantifies the reinforcing effect of confining pressure on the anchoring force.During the pull-out process of the anchor cable,the generation of failure cracks is in the order of orifice,bottom,and middle of the hole.Radial pressure can effectively enhance the ultimate pull-out force,alleviate the oscillation increase of pull-out force,and inhibit resin cracking,but will produce an external crushing zone.It also reveals the synergistic effect between bonding length and radial pressure,and successfully carries out industrial tests of anchor cable support,which ensures the stability of the stope roof and provides an important reference for the design of anchor cable support in deep high-stress mines.展开更多
This article investigates the radial electromagnetic force,vibration,and noise phenomenon in a low-speed,hightorque density spoke-type permanent magnet synchronous machine(ST-PMSM)designed with assisted poles having s...This article investigates the radial electromagnetic force,vibration,and noise phenomenon in a low-speed,hightorque density spoke-type permanent magnet synchronous machine(ST-PMSM)designed with assisted poles having symmetric and asymmetric topologies.Firstly,an analytical expression for the machine radial electromagnetic force(REMF)is derived to quickly estimate the REMF characteristics for the ST-PMSM with assisted poles having symmetric and asymmetric topologies.The 2D-Fourier decomposition method is applied to investigate the radial electromagnetic force harmonics(REMFHs).Secondly,Finite element(FE)models are designed for the machine structural analysis.Subsequently,the FE models and modal analysis are explored for different design cases of the analyzed machine.Lastly,vibration and noise behavior are investigated using an FE approach for the machine designs under symmetric and asymmetric assisted poles topologies.The findings indicate an increase in the richness of REMFHs,alongside a decrease in both the fundamental frequency and the lowest non-zero order of REMF,attributed to the presence of asymmetric assisted poles.Consequently,it is investigated that while considering the vibration and noise response in STPMSMs designed with asymmetric assisted poles topologies,it is essential to thoroughly account for induced non-zero low-order harmonics and their optimization for better vibration and noise performance.展开更多
A rotating neoclassical tearing mode(NTM)can increase the trapped ion losses when the frequency of the NTM is close to the precessional frequency of the trapped particles.When an equilibrium electric field,produced by...A rotating neoclassical tearing mode(NTM)can increase the trapped ion losses when the frequency of the NTM is close to the precessional frequency of the trapped particles.When an equilibrium electric field,produced by the rotation of the plasma and the density gradient,is present,the average precessional frequency of the trapped ions changes and so does the mode frequency corresponding to the maximum loss rate.Our results show that when an electric field with a value of 11.2 kV/m at q=2 is included the maximum of the trapped ion losses increases from 27% to 30% based on EAST equilibrium.展开更多
Tree growth is extremely vulnerable to climate change,especially in semi-arid areas.Although the response of stem radial growth(SRG)to climate change has been extensively studied,the intra-annual regulatory mechanisms...Tree growth is extremely vulnerable to climate change,especially in semi-arid areas.Although the response of stem radial growth(SRG)to climate change has been extensively studied,the intra-annual regulatory mechanisms of SRG in trees with different water use strategies and life types remain poorly understood.This study calculated the SRG of four native species in the semi-arid area of the Loess Plateau,China,including two isohydric species(Pinus tabuliformis Carrière and Populus×hopeiensis Hu&Chow)and two anisohydric species(Prunus sibirica L.and Platycladus orientalis(L.)Franco).The results revealed that the intra-annual SRG of all the four tree species exhibited a single peak,and greater SRG was found in anisohydric species.Principal component analysis and structural equation model revealed that atmospheric water,particularly relative humidity,was the main factor affecting the SRG of coniferous species(P.tabuliformis and P.orientalis),whereas the SRG was mainly affected by soil water content in broadleaf species(P.sibirica and P.×hopeiensis).These findings suggested that water use strategies and life types play important roles in SRG and environmental response of trees in semi-arid area.Considering the high climate sensitivity of wood formation in trees,our results highlight the importance of water use strategies and life types of trees in SRG prediction in the context of future climate change in arid and semi-arid areas.展开更多
We investigate the radial symmetry of minimizers on the Pohozaev-Nehari manifold to the Schrodinger Poisson equation with a general nonlinearity f(u).Particularly,we allow that f is L^(2) supercritical.The main result...We investigate the radial symmetry of minimizers on the Pohozaev-Nehari manifold to the Schrodinger Poisson equation with a general nonlinearity f(u).Particularly,we allow that f is L^(2) supercritical.The main result shows that minimizers are radially symmetric modulo suitable translations.展开更多
Radial rotating oscillating heat pipes(R-OHPs)have excellent thermal performance and great potential for application in the thermal management of rotatory machinery.However,the heat transport behavior and temperature ...Radial rotating oscillating heat pipes(R-OHPs)have excellent thermal performance and great potential for application in the thermal management of rotatory machinery.However,the heat transport behavior and temperature characteristics of R-OHPs are complex,and their understanding is still limited,hence necessitating further research.In this study,thanks to an experimental investigation involving a copper R-OHP running with acetone and water,its thermal performance is evaluated,and then the temperature characteristics are analyzed by nonlinear dynamic analysis.The study reveals that the effective heat transfer coefficient of R-OHPs undergoes a notable increase with rising rotational speed,exhibiting a peak at a threshold speed value.Such a peak is present irrespectively of the working fluid,and,after exceeding the threshold,higher rotational speeds lead to a lower thermal performance.Based on nonlinear dynamic analysis,the power spectrum density of the evaporator temperature indicates a lack of dominant frequency in temperature signals,suggesting a complex behavior characterized by random oscillations of vapor slugs and liquid plugs.In order to better understand how strong the chaotic behavior is,an autocorrelation analysis was carried out,the OHP at static state has a stronger chaos than R-OHPs.The correlation dimension analysis of the evaporator temperature provides values ranging from 1.2 to 1.6,which together with the Lyapunov exponent calculations,further support an evident chaotic nature of R-OHPs.展开更多
We developed an imaging technique combining two-photon computed super-resolution microscopy and suction-based stabilization to achieve the resolution of the single-cell level and organelles in vivo.To accomplish this,...We developed an imaging technique combining two-photon computed super-resolution microscopy and suction-based stabilization to achieve the resolution of the single-cell level and organelles in vivo.To accomplish this,a conventional two-photon microscope was equipped with a 3D-printed holders,which stabilize the tissue surface within the focal plane of immersion objectives.Further computational image stabilization and noise reduction were applied,followed by superresolution radial fluctuations(SRRF)analysis,doubling image resolution,and enhancing signal-to-noise ratios for in vivo subcellular process investigation.Stabilization of<1μm was obtained by suction,and<25 nm were achieved by subsequent algorithmic image stabilization.A Mito-Dendra2 mouse model,expressing green fluorescent protein(GFP)in mitochondria,demonstrated the potential of long-term intravital subcellular imaging.In vivo mitochondrial fission and fusion,mitochondrial status migration,and the effects of alcohol consumption(modeled as an alcoholic liver disease)and berberine treatment on hepatocyte mitochondrial dynamics are directly observed intravitally.Suction-based stabilization in two-photon intravital imaging,coupled with computational super-resolution holds promise for advancing in vivo subcellular imaging studies.展开更多
基金supported by the National Natural Science Foundation of China(Nos.U24B6001,52421002,52474016,and 52020105001)Research on Key Technologies for Exploration and Development of Dry Geothermal Resources(No.2022DJ5503)Deep-land National Science and Technology Major Project of China(No.2024ZD1003504).
文摘The strong vertical discontinuities pose a fundamental challenge to optimizing stimulated reservoir volume(SRV)in multilayered reservoirs.This research proposes a radial borehole-assisted horizontal well fracturing technology,which is expected to achieve effective vertical stimulation and commingled production across multiple pay zones.Under different geological and engineering conditions,the vertical propagation behavior of hydraulic fractures guided by radial boreholes can be determined by adjusting the interlayered lithologies and radial borehole configurations in experimental samples.Experimental results reveal four fracture network patterns:passivated,cross-layer,skip-layer,and hybrid fractures in the radial borehole fracturing.The radial boreholes perform better fracture guiding performances in the high-brittleness interlayers,which form cross-layer and hybrid fracture networks to improve the growth height.Hydraulic fractures tend to propagate from high-strength to low-strength layers under radial borehole guidance.When radial boreholes interconnect multiple lithology layers,hydraulic fractures initiate preferentially in lower-strength zones rather than remaining confined to borehole root ends.Increased radial borehole length and diameter facilitate fracture skip-layer initiation and cross-layer propagation,while multiple borehole branches enhance fracture penetration across high-strength interlayers.Radial boreholes with inclination angles below 30°enhance fracture height by generating cross-layer and hybrid fracture networks.Furthermore,an inter-borehole phase angle of less than 180°facilitates single-wing fracture cross-layer propagation.Fracture height is primarily governed by radial borehole length,followed by quantity,inclination angle,and diameter.Based on the geometric similarity criteria,the recommended parameters for radial borehole-assisted fracturing in a 5 1/2-inch horizontal well include a length>15 m,an inclination angle<30°,and a diameter>52 mm to ensure effective stimulation across three or more pay zones.Finally,the field-scale numerical model was developed to simulate the optimized radial borehole fracturing and demonstrate the technical superiority.These findings are expected to provide an in-depth understanding of the effective stimulation in multilayered reservoirs.
基金Supported by the National Basic Research Program of China(2012CB025904)Zhengzhou Shengda University of Economics,Business and Management(SD-YB2025085)。
文摘Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.
文摘AIM:To describe the technique and the outcomes of manual Bowman layer and stroma transplant-onlay(BLST-o)for 2 cases of radial keratotomy(RK).METHODS:Two patients with visual fluctuations and corneal irregularity due to RK were offered manual BLST-o as an alternative to penetrating keratoplasty(PKP).Visual acuity,refraction,corneal topography,corneal aberrometry,and corneal optical coherence tomography(OCT)pre-and postoperative were analyzed.Histology was obtained for 1 case.RESULTS:Both patients had corneal anatomical and morphological improvement,with elimination of the visual fluctuations.In one case,a subsequent excimer laser treatment improved corneal shape further,thus improving vision.The other case,whereas initially improved,developed epithelial ingrowth following suture removal.The latter was explanted and had a xenogeneic implant.The explanted sample was sent for histology,showing a viable graft of Bowman layer and anterior stroma.CONCLUSION:Manual BLST-o is a potential option for the management of symptoms post RK.These grafts may facilitate subsequent treatments such as laser corrections,and may not preclude from other interventions after explantation.
文摘The number and diversity of inhibitory neurons(INs)increased substantially during mammalian brain evolution.However,the generative mechanisms of the vast repertoire of human INs remain elusive.We performed spatial and single-cell transcriptomics of human medial ganglionic eminence(hMGE),a pivotal source of cortical and subpallial INs,and built the trajectories of hMGE-derived cells during brain development.We identified spatiotemporally and molecularly segregated progenitor cell populations fated to produce distinct IN types.
文摘Transradial access (TRA) has emerged as the preferred vascular access route forcoronary angiography and percutaneous coronary interventions due to itssuperior safety profile compared to transfemoral access. However, its widespreadadoption raises concerns regarding structural alterations in the radial artery,which may impact long-term vascular health and future procedural feasibility.TRA is associated with histopathologic changes in the arterial wall, such asintimal injury and hyperplasia, medial remodeling and adventitial inflammation,collectively contributing to radial artery remodeling. Moreover, TRA can inducechanges in radial artery lumen diameter driven by an inflammatory response dueto arterial puncture and mechanical friction during the procedure. Nonetheless, amore clinically significant consequence is radial artery occlusion, which is influencedby various procedural and patient-related factors. Strategies to minimizeremodeling include meticulous pre-procedural ultrasound assessment to ensureappropriate sheath-to-artery size matching, periprocedural pharmacologicalinterventions and implementation of patent hemostasis techniques. This reviewsynthesizes current knowledge regarding the mechanisms, clinical implications,and preventive strategies related to radial artery remodeling following TRA. Further research is needed toelucidate the long-term consequences of radial artery remodeling and to refine preventive strategies for preservingradial artery patency and its suitability for future interventions.
文摘Radial head(RH)arthroplasty(RHA)has emerged as a critical intervention in the management of complex elbow fractures,particularly Mason type III and IV injuries where the native RH is irreparable.Beyond its role in pain relief and joint congruity,RHA serves as a biomechanical cornerstone for restoring the lateral column and ensuring elbow stability,especially in the presence of associated ligamentous injuries or fracture-dislocations.This editorial synthesizes current evidence on RHA in Mason type III and IV RH fractures,with attention to biomechanical rationale,implant design,and complication trends.Aiming to reaffirm RHA’s position as a vital tool in contemporary elbow trauma care,a simplified treatment algorithm is presented to support individualized surgical decisionmaking.
文摘BACKGROUND Radial head fractures constitute approximately one-third of all elbow fractures,significantly impacting the young and active population.While open reduction and internal fixation is the preferred treatment for displaced fractures,its high complication rate in comminuted fractures has led to the increasing use of radial head arthroplasty(RHA).RHA provides improved functional outcomes with fewer complications,yet its long-term efficacy remains a topic of debate.AIM To evaluate the functional outcomes of patients undergoing RHA with a modular metallic prosthesis for comminuted Mason type III and IV radial head fractures.METHODS A prospective and retrospective hospital-based study was conducted at Dayanand Medical College and Hospital,Ludhiana over 32 months(January 2021-August 2023).A total of 26 patients with Mason type III and IV fractures were included,with six retrospective and 20 prospective cases.Functional outcomes were assessed using the Mayo Elbow Performance Score(MEPS),elbow range of motion,pain via Visual Analog Scale,and activities of daily living at immediate postoperative,three-month,and six-month follow-ups.RESULTS MEPS at 6 months follow up for 4 cases(15.38%)had good scores,and 22 cases(84.62%)had excellent scores,with a mean±SD of 97.31±6.67.Comparisons showed significant improvement from immediate post-operative to 3 months(P<0.0001),from immediate post-operative to 6 months(P<0.0001),and between 3 months and 6 months(P<0.0001).None of the patients had elbow instability after radial head replacement and 22 cases(84.62%)had no complications,while 3 cases(11.54%)had a stiff elbow,and 1 case(3.85%)had heterotopic ossification.CONCLUSION RHA is an effective treatment for comminuted radial head fractures,providing stable elbow function with minimal complications.
基金supported by the National Natural Science Foun-dation of China(52421002,U24B6001,52204019,and 52192624)the Open Foundation of the Shanxi Key Laboratory of Carbon Dioxide Sequestration and Enhanced Oil Recovery。
文摘Medium-high maturity continental shale oil is one of the hydrocarbon resources with the most potential for successful development in China.Nevertheless,the unique geological conditions of a multi-lithologic superposition shield the vertical propagation of hydraulic fractures and limit the longitudinal reconstruction in reservoirs,posing a great challenge for large-scale volumetric fracturing.Radial wellbore crosslayer fracturing,which transforms the interaction between the hydraulic fractures and lithologic interface into longitudinal multilayer competitive initiation,could provide a potential solution for this engineering challenge.To determine the longitudinal propagation behaviors of fractures guided by radial wellbores,true triaxial fracturing experiments were performed on multilayer shale-sandstone samples,with a focus on the injection pressure response,fracture morphology,and cross-layer pattern.The effects of the radial borehole length L,vertical stress difference K_(v),injection rate Q,and viscosity m of the fracturing fluid were analyzed.The results indicate that radial wellbores can greatly facilitate fracture initiation and cross-layer propagation.Unlike conventional hydraulic fracturing,there are two distinct fracture propagation patterns in radial wellbore fracturing:cross-layering and skip-layering.The fracture height guided by a radial wellbore is positively correlated with K_(v),Q,and m.Increasing these parameters causes a shift in the fracture initiation from a single root to an asynchronous root/toe end and can improve the cross-layer propagation capacity.Critical parameter thresholds exist for fracture propagation through and across interlayers under the guidance of radial boreholes.A parameter combination of critical cross-layering/skip-layering or alternating displacement/viscosity is recommended to simultaneously improve the fracture height and degree of lateral activation.The degree of correlation of different parameters with the vertical fracture height can be written as L>Q/m>K_(v).Increasing the radial wellbore length can effectively facilitate fracture cross-/skip-layer propagation and reduce the critical threshold of injection parameters,which is conducive to maximizing the stimulated reservoir volume.
文摘This study examines the influence of magnetic field and temperature on the transient voltage of a polycrystalline silicon radial junction solar cell in a dynamic regime under multispectral illumination. Radial junction solar cells represent a major advancement in photovoltaic technologies, as they optimize light absorption and charge collection efficiency. The focus is on the impact of the magnetic field and temperature on the decay of transient voltage, which provides crucial information on recombination processes and the lifetime of minority carriers. The results reveal that the magnetic field tends to increase the transient voltage by directly affecting the transient electron density. Indeed, for B > 7 × 10−5 T, the magnetic field prolongs the relaxation time by increasing the transient voltage amplitude. Additionally, rising temperatures accelerate (ranging from 290 K to 450 K) recombination processes, thereby reducing the transient voltage, although this effect is moderated by the presence of a magnetic field. The study highlights the complex interaction between magnetic field and temperature, with significant impacts on the transient behaviour.
文摘This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity factor (LSF), genetic algorithms (GA) methods, and numerical method based on LSF. The methodology aims to determine the optimal allocation and sizing of multiple PV-DG to minimize power loss through time series power flow analysis. An approach utilizing continuous sensitivity analysis is developed and inherently leverages power flow and loss equations to compute LSF of all buses in the system towards employing a dynamic PV-DG model for more accurate results. The algorithm uses a numerical grid search method to optimize PV-DG placement in a power distribution system, focusing on minimizing system losses. It combines iterative analysis, sensitivity assessment, and comprehensive visualization to identify and present the optimal PV-DG configurations. The present-ed algorithms are verified through co-simulation framework combining MATLAB and OpenDSS to carry out analysis for 12-bus radial distribution test system. The proposed numerical method is compared with other algorithms, such as ELF, LSF methods, and Genetic Algorithms (GA). Results show that the proposed numerical method performs well in comparison with LSF and ELF solutions.
基金supported by the National Natural Science Foundation of China(Grants Nos.42130511,42261134537 and 41602192)funded by the Russian Science Foundation(Grant No.23-44-00067)+2 种基金supported by the Swedish Research Council(Vetenskaps lijeradet,Grant No.2023-00605)the Marianne and Marcus Wallenberg Foundation(Grant No.MMW 2022-0114)the Centre for Advanced Study(CAS)at the Norwegian Academy of Science and Letters,which funded and hosted the research project“The Nordic Little Ice Age”during the 2024-2025 academic year。
文摘Radial growth of trees is highly sensitive to environmental changes,but the effect of climate on tree rings in Qinghai spruce(Picea crassifolia),a widely distributed endemic conifer in western China,is more complex than in many other conifers.A comprehensive understanding of the spatiotemporal climatic responses of its rings is needed to develop theoretical basis for designing strategies for its conservation and management.Here,our synthesis of the literature on responses of radial growth of Qinghai spruce to monthly climate variables in different environmental conditions by meta-analysis showed that precipitation and drought severity are the main limiting factors for Qinghai spruce radial growth in the semiarid region of northwestern China.In warmer and drier areas,radial growth of Qinghai spruce is mainly limited by drought.In the areas north of the 600-mm annual precipitation isoline,the tree-ring width(TRW)was significantly positively correlated with precipitation and significantly negatively correlated with temperature during the growing season(June-August).The limiting effect of drought on Qinghai spruce is also gradually increasing from southeast to northwest,to the west of 103°E and within 37°N-39°N.
基金supported by the Russian Science Foundation(Grant No.23-11-00242).
文摘An experimental study of the diffusive mass transfer between a droplet and an oscillating immiscible liquid in a horizontal axisymmetricHele-Shaw cell is carried out.Theliquid oscillates radially in the cell.Thetransverse size of the droplet exceeds the cell thickness.The viscosities of the droplet and the surrounding liquid are comparable.Relevant effort is provided to design and test an experimental setup and validate a protocol for determining the mass transfer rate of a solute in a two-liquid system.In particular,fluorescent dye Rhodamine B is considered as the solute.A critical comparison of the situations with and without oscillation is implemented.A procedure is introduced and validated to determine the molecular and effective diffusion coefficients through evaluation of the growth of the diffusion zone width over time.It is shown that,in the presence of the liquid oscillations,there is a significant increase in the width of the zone in which Rhodamine B is present compared to the reference case with no oscillations.The oscillatory flow leads to an intensification of the solute diffusion due to intense time-averaged flows inside the droplet and the surrounding liquid and oscillations of the drop itself.Thestudy is of significant practical interest with particular relevance to typical processes for liquid-liquid extraction.
基金supported by the National Natural Science Foundation of China(Grant NO.41601198,41701209)the key fund project of Beijing Municipal Research Institute of Eco-Environmental Protection(No.Y2024-002).
文摘Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of Xiaowutai Mountain,four Chinese pine(Pinus tabulaeformis)ring-width index chronologies were established at different elevations(1290–1600 m).Species growth trends were estimated using climate change projections derived from global climate models.The results show:(1)the four ring-width chronologies exhibited strong statistical characteristics,making them suitable for dendroclimatology studies.Radial growth-climate relationships were highly consistent,showing a negative correlation with previous September temperatures and current May–June temperatures,as well as a positively correlated with precipitation and Palmer Drought Severity Index during the corresponding period;and(2)climate change scenarios revealed that temperature will gradually increase on the Xiaowutai Mountain,and only a slight variation in precipitation is expected.Chinese pine radial growth may show a decline under future climate change.
基金Financial supports for this work,provided by the National Natural Science Foundation Project of China(No.52374152)the Guangxi Science and Technology Plan Project of China(No.2022AB31023)the National Basic Research Development Program of China(No.2022YFC2904602)are gratefully acknowledged。
文摘The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure conditions.Through field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study clarifies the relationship between radial pressure and bonding length for the ultimate pullout force and reveals the microscopic failure process of the resin-rock interface in the anchoring system.The results show that the ultimate load increases with the increase of bonding length in three different stages:rapid,slow,and uniform growth.The new mechanical model developed considering radial pressure describes the inverse relationship between radial pressure and the plastic zone on the bonding section,and quantifies the reinforcing effect of confining pressure on the anchoring force.During the pull-out process of the anchor cable,the generation of failure cracks is in the order of orifice,bottom,and middle of the hole.Radial pressure can effectively enhance the ultimate pull-out force,alleviate the oscillation increase of pull-out force,and inhibit resin cracking,but will produce an external crushing zone.It also reveals the synergistic effect between bonding length and radial pressure,and successfully carries out industrial tests of anchor cable support,which ensures the stability of the stope roof and provides an important reference for the design of anchor cable support in deep high-stress mines.
基金supported by the National Key Research and Developmen Program of China(2022YFB3403100)。
文摘This article investigates the radial electromagnetic force,vibration,and noise phenomenon in a low-speed,hightorque density spoke-type permanent magnet synchronous machine(ST-PMSM)designed with assisted poles having symmetric and asymmetric topologies.Firstly,an analytical expression for the machine radial electromagnetic force(REMF)is derived to quickly estimate the REMF characteristics for the ST-PMSM with assisted poles having symmetric and asymmetric topologies.The 2D-Fourier decomposition method is applied to investigate the radial electromagnetic force harmonics(REMFHs).Secondly,Finite element(FE)models are designed for the machine structural analysis.Subsequently,the FE models and modal analysis are explored for different design cases of the analyzed machine.Lastly,vibration and noise behavior are investigated using an FE approach for the machine designs under symmetric and asymmetric assisted poles topologies.The findings indicate an increase in the richness of REMFHs,alongside a decrease in both the fundamental frequency and the lowest non-zero order of REMF,attributed to the presence of asymmetric assisted poles.Consequently,it is investigated that while considering the vibration and noise response in STPMSMs designed with asymmetric assisted poles topologies,it is essential to thoroughly account for induced non-zero low-order harmonics and their optimization for better vibration and noise performance.
基金partially supported by the Comisión Nacional de Energía Atómica,CNEA(Controlled Nuclear Fusion Program),CONICET(No.11220200101929CO)Universidad Nacional de Cuyo(No.06-C565).
文摘A rotating neoclassical tearing mode(NTM)can increase the trapped ion losses when the frequency of the NTM is close to the precessional frequency of the trapped particles.When an equilibrium electric field,produced by the rotation of the plasma and the density gradient,is present,the average precessional frequency of the trapped ions changes and so does the mode frequency corresponding to the maximum loss rate.Our results show that when an electric field with a value of 11.2 kV/m at q=2 is included the maximum of the trapped ion losses increases from 27% to 30% based on EAST equilibrium.
基金financial support from the National Natural Science Foundation of China(32125028,32192431)the Science and Technology Major Project of Gansu Province,China(23ZDKA0006).
文摘Tree growth is extremely vulnerable to climate change,especially in semi-arid areas.Although the response of stem radial growth(SRG)to climate change has been extensively studied,the intra-annual regulatory mechanisms of SRG in trees with different water use strategies and life types remain poorly understood.This study calculated the SRG of four native species in the semi-arid area of the Loess Plateau,China,including two isohydric species(Pinus tabuliformis Carrière and Populus×hopeiensis Hu&Chow)and two anisohydric species(Prunus sibirica L.and Platycladus orientalis(L.)Franco).The results revealed that the intra-annual SRG of all the four tree species exhibited a single peak,and greater SRG was found in anisohydric species.Principal component analysis and structural equation model revealed that atmospheric water,particularly relative humidity,was the main factor affecting the SRG of coniferous species(P.tabuliformis and P.orientalis),whereas the SRG was mainly affected by soil water content in broadleaf species(P.sibirica and P.×hopeiensis).These findings suggested that water use strategies and life types play important roles in SRG and environmental response of trees in semi-arid area.Considering the high climate sensitivity of wood formation in trees,our results highlight the importance of water use strategies and life types of trees in SRG prediction in the context of future climate change in arid and semi-arid areas.
基金supported by the NSFC(12031015)Song's research was supported by the Shuimu Tsinghua Scholar Program,the National Funded Postdoctoral Research Program(GZB20230368)the China Postdoctoral Science Foundation(2024T170452)。
文摘We investigate the radial symmetry of minimizers on the Pohozaev-Nehari manifold to the Schrodinger Poisson equation with a general nonlinearity f(u).Particularly,we allow that f is L^(2) supercritical.The main result shows that minimizers are radially symmetric modulo suitable translations.
基金Supported by National Natural Science Foundation of China(Grant No.52205476)Jiangsu Provincial Natural Science Foundation(Grant No.BK20242040)+2 种基金Fundamental Research Funds for the Central Universities(Grant No.NG2024008)the Youth Talent Support Project of CASTthe Fund of Jiangsu Key Laboratory of Precision and Micro-Manufacturing Technology(Grant No.1005-ZAA20003-14)。
文摘Radial rotating oscillating heat pipes(R-OHPs)have excellent thermal performance and great potential for application in the thermal management of rotatory machinery.However,the heat transport behavior and temperature characteristics of R-OHPs are complex,and their understanding is still limited,hence necessitating further research.In this study,thanks to an experimental investigation involving a copper R-OHP running with acetone and water,its thermal performance is evaluated,and then the temperature characteristics are analyzed by nonlinear dynamic analysis.The study reveals that the effective heat transfer coefficient of R-OHPs undergoes a notable increase with rising rotational speed,exhibiting a peak at a threshold speed value.Such a peak is present irrespectively of the working fluid,and,after exceeding the threshold,higher rotational speeds lead to a lower thermal performance.Based on nonlinear dynamic analysis,the power spectrum density of the evaporator temperature indicates a lack of dominant frequency in temperature signals,suggesting a complex behavior characterized by random oscillations of vapor slugs and liquid plugs.In order to better understand how strong the chaotic behavior is,an autocorrelation analysis was carried out,the OHP at static state has a stronger chaos than R-OHPs.The correlation dimension analysis of the evaporator temperature provides values ranging from 1.2 to 1.6,which together with the Lyapunov exponent calculations,further support an evident chaotic nature of R-OHPs.
基金supported by the Ministry of Science,ICT and Future Planning(MSIP)through the National Research Foundation of Korea(NRF)(RS-2024-00450201)supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health and Welfare,Republic of Korea(HI22C1374).
文摘We developed an imaging technique combining two-photon computed super-resolution microscopy and suction-based stabilization to achieve the resolution of the single-cell level and organelles in vivo.To accomplish this,a conventional two-photon microscope was equipped with a 3D-printed holders,which stabilize the tissue surface within the focal plane of immersion objectives.Further computational image stabilization and noise reduction were applied,followed by superresolution radial fluctuations(SRRF)analysis,doubling image resolution,and enhancing signal-to-noise ratios for in vivo subcellular process investigation.Stabilization of<1μm was obtained by suction,and<25 nm were achieved by subsequent algorithmic image stabilization.A Mito-Dendra2 mouse model,expressing green fluorescent protein(GFP)in mitochondria,demonstrated the potential of long-term intravital subcellular imaging.In vivo mitochondrial fission and fusion,mitochondrial status migration,and the effects of alcohol consumption(modeled as an alcoholic liver disease)and berberine treatment on hepatocyte mitochondrial dynamics are directly observed intravitally.Suction-based stabilization in two-photon intravital imaging,coupled with computational super-resolution holds promise for advancing in vivo subcellular imaging studies.
