Objective To reveal and compare the immunogenicity of glycoprotein from nucleus pulposus and collagen from anulus fibrosus in rabbit intervertebral disc.Methods According to the similarity principle of genome biology ...Objective To reveal and compare the immunogenicity of glycoprotein from nucleus pulposus and collagen from anulus fibrosus in rabbit intervertebral disc.Methods According to the similarity principle of genome biology and the amount展开更多
Glaxo Laboratories, Bombay, have prepared a potent tetanus vaccine of 250 Lf as a substitute of the previous 5 Lf tetanus vaccine. The safety evaluation of the vaccine has been reported, but the teratogenic potential ...Glaxo Laboratories, Bombay, have prepared a potent tetanus vaccine of 250 Lf as a substitute of the previous 5 Lf tetanus vaccine. The safety evaluation of the vaccine has been reported, but the teratogenic potential was not studied. In the experiment reported herein we have studied the teratogenic action of the vaccine in the progeny of rabbits. No congenital anomalies were observed.展开更多
To evaluate the effect of hepatic inflow occlusion on the liver remnant, three methods of inflow occlusion of the right outside lobe of liver, which was finally resected, were performed in 30 rabbits. The mortality ra...To evaluate the effect of hepatic inflow occlusion on the liver remnant, three methods of inflow occlusion of the right outside lobe of liver, which was finally resected, were performed in 30 rabbits. The mortality rate of 12 animals (6 in Group Ⅰ and 6 in Group Ⅱ) undergone 30 minutes of portal triad clamping (PTC) and selective hepatic artery reserving (SHAR) was both 66.7%. No death occurred in Group Ⅲ (PTC, n = 6) and Ⅳ (SHAR, n = 6) for 20 minutes of hepatic ischemia, but with an irreversible damage to the hepatocytes. The level of serum glutamic-yruvic transaminase (GPT) in Groups Ⅲ and Ⅳ animals rose to 282.17 U / L and 155.33 U / L on the first postoperative day and thereafter declining slowly to the preoperative level on the 5th and 3rd days, respectively. In Group V with selective hemihepatic vascular occlusion (SHHVO) serum GPT showed only temporary mild rise (112.83 U / L) on the first postoperative day and no hepatic pathologic change appeared. It is obvious that the function of the liver remnant can be best preserved during hepatic resection under SHHVO.展开更多
文摘Objective To reveal and compare the immunogenicity of glycoprotein from nucleus pulposus and collagen from anulus fibrosus in rabbit intervertebral disc.Methods According to the similarity principle of genome biology and the amount
文摘Glaxo Laboratories, Bombay, have prepared a potent tetanus vaccine of 250 Lf as a substitute of the previous 5 Lf tetanus vaccine. The safety evaluation of the vaccine has been reported, but the teratogenic potential was not studied. In the experiment reported herein we have studied the teratogenic action of the vaccine in the progeny of rabbits. No congenital anomalies were observed.
文摘To evaluate the effect of hepatic inflow occlusion on the liver remnant, three methods of inflow occlusion of the right outside lobe of liver, which was finally resected, were performed in 30 rabbits. The mortality rate of 12 animals (6 in Group Ⅰ and 6 in Group Ⅱ) undergone 30 minutes of portal triad clamping (PTC) and selective hepatic artery reserving (SHAR) was both 66.7%. No death occurred in Group Ⅲ (PTC, n = 6) and Ⅳ (SHAR, n = 6) for 20 minutes of hepatic ischemia, but with an irreversible damage to the hepatocytes. The level of serum glutamic-yruvic transaminase (GPT) in Groups Ⅲ and Ⅳ animals rose to 282.17 U / L and 155.33 U / L on the first postoperative day and thereafter declining slowly to the preoperative level on the 5th and 3rd days, respectively. In Group V with selective hemihepatic vascular occlusion (SHHVO) serum GPT showed only temporary mild rise (112.83 U / L) on the first postoperative day and no hepatic pathologic change appeared. It is obvious that the function of the liver remnant can be best preserved during hepatic resection under SHHVO.
