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RIPASA评分和血清总胆红素及C反应蛋白在急性阑尾炎中的诊断价值研究 被引量:16
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作者 艾龙龙 张玉江 +3 位作者 张童鑫 张耀军 阿合提别克.塔布斯 芦小龙 《中国全科医学》 CAS 北大核心 2018年第32期3961-3966,共6页
目的探讨RIPASA评分、血清总胆红素(TBil)、C反应蛋白(CRP)在急性阑尾炎中的诊断价值。方法选取2016年1月—2017年1月新疆医科大学第二附属医院收治的250例急性右下腹痛患者,根据腹腔镜阑尾切除术及病理检查结果将其分为急性阑尾炎组(15... 目的探讨RIPASA评分、血清总胆红素(TBil)、C反应蛋白(CRP)在急性阑尾炎中的诊断价值。方法选取2016年1月—2017年1月新疆医科大学第二附属医院收治的250例急性右下腹痛患者,根据腹腔镜阑尾切除术及病理检查结果将其分为急性阑尾炎组(150例)和非急性阑尾炎组(100例),急性阑尾炎组根据病理类型分为A亚组(单纯性阑尾炎18例)、B亚组(化脓性阑尾炎76例)、C亚组(坏疽穿孔性阑尾炎56例)。入院时对患者行RIPASA评分,并检测TBil及CRP水平,采用受试者工作特征(ROC)曲线分析其诊断价值。结果急性阑尾炎组RIPASA评分、TBil、CRP水平均高于非急性阑尾炎组(P<0.001)。B亚组RIPASA评分、CRP水平均高于A亚组(P<0.05);C亚组RIPASA评分、TBil、CRP水平均高于A亚组,TBil、CRP水平均高于B亚组(P<0.05)。RIPASA评分诊断急性阑尾炎的最佳临界值为7.5分,准确率为82.4%,灵敏度为88.7%,特异度为73.0%,ROC曲线下面积(AUC)为0.89[95%CI(0.84,0.93),P<0.001];TBil诊断急性阑尾炎的最佳临界值为14.15μmol/L,准确率为84.4%,灵敏度为88.7%,特异度为78.0%,AUC为0.86[95%CI(0.81,0.90),P<0.001];CRP诊断急性阑尾炎的最佳临界值为13.6 mg/L,准确率为84.0%,灵敏度为88.0%,特异度为78.0%,AUC为0.88[95%CI(0.84,0.92),P<0.001]。TBil诊断坏疽穿孔性阑尾炎的最佳临界值为20.28μmol/L,准确率为80.0%,灵敏度为89.3%,特异度为74.5%,AUC为0.89[95%CI(0.82,0.93),P<0.001];CRP诊断坏疽穿孔性阑尾炎的最佳临界值为34.0mg/L,准确率为76.0%,灵敏度为82.1%,特异度为72.3%,AUC为0.82[95%CI(0.75,0.88),P<0.001]。结论 RIPASA评分、TBil、CRP对急性阑尾炎均有诊断价值;TBil、CRP可以预测坏疽穿孔性阑尾炎。 展开更多
关键词 阑尾炎 ripasa评分 胆红素 C反应蛋白质 阑尾切除术 诊断 灵敏度 特异度
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改良Alvarado、AIR、RIPASA和AAS评分对成人急性阑尾炎风险预测价值 被引量:1
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作者 王贺然 郑志强 王培戈 《临床医学进展》 2022年第10期9705-9719,共15页
目的:急性阑尾炎是常见的急腹症之一,早期识别和治疗能有效降低急性阑尾炎发生坏疽穿孔等并发症。本研究旨在确定适合中国的成人急性阑尾炎的最佳风险预测模型。方法:回顾性收集了269例拟诊断且术后病理明确是急性阑尾炎患者的改良Alvar... 目的:急性阑尾炎是常见的急腹症之一,早期识别和治疗能有效降低急性阑尾炎发生坏疽穿孔等并发症。本研究旨在确定适合中国的成人急性阑尾炎的最佳风险预测模型。方法:回顾性收集了269例拟诊断且术后病理明确是急性阑尾炎患者的改良Alvarado、AIR、RIPASA和AAS评分相关数据,研究不同评分模型对中国成人急性阑尾炎的预测价值及风险评估。结果:共纳入269名疑似阑尾炎患者,平均年龄为38岁,男性156名(58%),各组评分对单纯性及复杂性阑尾炎的预测具有意义(P < 0.01),而改良Alvarado在评价阑尾炎坏疽穿孔时更有意义(P = 0.001),中性粒细胞百分比在单纯性阑尾炎和化脓性或坏疽性阑尾炎时具有统计学意义(P = 0.015和P = 0.001),CRP在单纯性和化脓性阑尾炎;单纯性和坏疽/穿孔性阑尾炎;化脓性与坏疽性阑尾炎之间均具有显著差异(P = 0.002, P < 0.001, P < 0.001)。参照受试者工作曲线,发现在评估复杂性急性阑尾炎的改良Alvarado评分的最佳评分为5.5,敏感性为76.3%,特异性为52%;而AAS评分最佳截断值为11.5,敏感性为92.2%,特异性为72%;改良Alvarado评分对坏疽/穿孔性阑尾炎的最佳评分为6.5,敏感性为71.2%,特异性为50.3%。结论:与RIPASA和AAS评分相比,改良Alvarado评分、AIR评分在评估急性阑尾炎坏疽穿孔方面具有最佳筛查性能,在识别急性阑尾炎患者时更有价值。 展开更多
关键词 急性阑尾炎 改良Alvarado评分 AIR评分 ripasa评分 AAS评分
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Evaluation of modifi ed Alvarado scoring system and RIPASA scoring system as diagnostic tools of acute appendicitis 被引量:14
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作者 Abdullah Shuaib Ali Shuaib +3 位作者 Zainab Fakhra Bader Marafi Khalid Alsharaf Abdullah Behbehani 《World Journal of Emergency Medicine》 CAS 2017年第4期276-280,共5页
BACKGROUND: Acute appendicitis is the most common surgical condition presented in emergency departments worldwide. Clinical scoring systems, such as the Alvarado and modified Alvarado scoring systems, were developed w... BACKGROUND: Acute appendicitis is the most common surgical condition presented in emergency departments worldwide. Clinical scoring systems, such as the Alvarado and modified Alvarado scoring systems, were developed with the goal of reducing the negative appendectomy rate to 5%–10%. The Raja Isteri Pengiran Anak Saleha Appendicitis(RIPASA) scoring system was established in 2008 specif ically for Asian populations. The aim of this study was to compare the modif ied Alvarado with the RIPASA scoring system in Kuwait population.METHODS: This study included 180 patients who underwent appendectomies and were documented as having "acute appendicitis" or "abdominal pain" in the operating theatre logbook(unit B) from November 2014 to March 2016. The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV), diagnostic accuracy, predicted negative appendectomy and receiver operating characteristic(ROC) curve of the modified Alvarado and RIPASA scoring systems were derived using SPSS statistical software.RESULTS: A total of 136 patients were included in this study according to our criteria. The cut-off threshold point of the modif ied Alvarado score was set at 7.0, which yielded a sensitivity of 82.8% and a specif icity of 56%. The PPV was 89.3% and the NPV was 42.4%. The cut-off threshold point of the RIPASA score was set at 7.5, which yielded a 94.5% sensitivity and an 88% specif icity. The PPV was 97.2% and the NPV was 78.5%. The predicted negative appendectomy rates were 10.7% and 2.2% for the modif ied Alvarado and RIPASA scoring systems, respectively. The negative appendectomy rate decreased significantly, from 18.4% to 10.7% for the modified Alvarado, and to 2.2% for the RIPASA scoring system, which was a signif icant difference(P<0.001) for both scoring systems.CONCLUSION: Based on the results of this study, the RIPASA score is a simple scoring system with better sensitivity and specif icity than the modif ied Alvarado scoring system in Asian populations. It consists of 14 clinical parameters that can be obtained from a good patient history, clinical examination and laboratory investigations. The RIPASA scoring system is more accurate and specific than the modif ied Alvarado scoring system for Kuwait population. 展开更多
关键词 ACUTE APPENDICITIS Modifi ED Alvarado SCORE ripasa SCORE
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