This study compared the efficacy of 70- and 120-w 2-μm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with sympto...This study compared the efficacy of 70- and 120-w 2-μm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (t〉 60 ml) who underwent either 70-w (n=44) or 120-w ThuVEP (n=40) non-randomly was carried out. Patient demographics and perioperative and 12-month follow-up data were analysed. The mean prostate volume was 79.90---27.49 ml in patients who had received 70-w ThuVEP, which was less than in those who had received 120-w ThuVEP (88.53+-25.10; P=0.033). The mean enucleation (resected weight/laser time, 2.16±1.21 g min-1 vs. 1.23±0.60 g min-1; P=-0.013), operation efficiency (resected weight/total operation time, 0.76±0.35 g min-1 vs. 0.42+-0.27 g min-1; P=-0.000) and percentage of resected tissue (66.93%±22.79% vs. 45.41%±23.33%; P=-0.000) were higher with 120-w treatment compared to 70-w ThuVEP. One patient (1.2% of total patients) (in the 120-w group) required a blood transfusion postoperatively. Sixty-one patients (73%) were available for review at the 12-month follow-up time point. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), postvoiding residual urine (PVR) and prostate volume improved significantly after treatment (P≤ 0.035) and were not significantly different between those treated with the different devices (70- and 120-w). The median prostate volume reduction was 81.70% and 82.19% with 70- and 120-w ThuVEP, respectively. The incidence of complications was low and did not differ between groups treated with the different devices. Two patients (2.4%) (one per group) had a bladder neck contracture at the follow-up. ThuVEP is a safe and efficacious procedure for the treatment of symptomatic BPO. The incidence of complications was low with both devices. The 120-w thulium:YAG device enhances the effectiveness of Th,VEP with reeard to the oercentaee of resected tissue and the enucleation/ooeration efficiency.展开更多
目的:探讨宫腔镜2μm激光治疗围绝经期功能失调性子宫出血(简称功血)的临床疗效。方法:以26例宫腔镜2μm激光子宫内膜去除术治疗的围绝经期功血患者为观察组,26例经宫腔镜子宫内膜电切术治疗的患者为对照组,对两组的手术时间、术中出血...目的:探讨宫腔镜2μm激光治疗围绝经期功能失调性子宫出血(简称功血)的临床疗效。方法:以26例宫腔镜2μm激光子宫内膜去除术治疗的围绝经期功血患者为观察组,26例经宫腔镜子宫内膜电切术治疗的患者为对照组,对两组的手术时间、术中出血量及临床疗效进行比较。结果:观察组的手术时间明显长于对照组(16.9±4.5 min vs 13.9±3.8 min),术中出血量少于对照组(10.6±3.5 mL vs 14.2±4.2 mL),两组比较差异均有统计学意义(P<0.05);观察组总有效率为92.3%,对照组总有效率为96.2%,差异无统计学意义(P>0.05)。结论:宫腔镜2μm激光治疗围绝经期功血疗效确切,并发症少,是一种安全、简便、有效的方法,但对其长远疗效尚须进一步观察。展开更多
文摘This study compared the efficacy of 70- and 120-w 2-μm thulium:YAG VapoEnucleation of the prostate (ThuVEP) for patients with benign prostatic obstruction (BPO). A prospective analysis of 84 patients with symptomatic BPO and prostatic enlargement (t〉 60 ml) who underwent either 70-w (n=44) or 120-w ThuVEP (n=40) non-randomly was carried out. Patient demographics and perioperative and 12-month follow-up data were analysed. The mean prostate volume was 79.90---27.49 ml in patients who had received 70-w ThuVEP, which was less than in those who had received 120-w ThuVEP (88.53+-25.10; P=0.033). The mean enucleation (resected weight/laser time, 2.16±1.21 g min-1 vs. 1.23±0.60 g min-1; P=-0.013), operation efficiency (resected weight/total operation time, 0.76±0.35 g min-1 vs. 0.42+-0.27 g min-1; P=-0.000) and percentage of resected tissue (66.93%±22.79% vs. 45.41%±23.33%; P=-0.000) were higher with 120-w treatment compared to 70-w ThuVEP. One patient (1.2% of total patients) (in the 120-w group) required a blood transfusion postoperatively. Sixty-one patients (73%) were available for review at the 12-month follow-up time point. The quality of life (QoL), International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), postvoiding residual urine (PVR) and prostate volume improved significantly after treatment (P≤ 0.035) and were not significantly different between those treated with the different devices (70- and 120-w). The median prostate volume reduction was 81.70% and 82.19% with 70- and 120-w ThuVEP, respectively. The incidence of complications was low and did not differ between groups treated with the different devices. Two patients (2.4%) (one per group) had a bladder neck contracture at the follow-up. ThuVEP is a safe and efficacious procedure for the treatment of symptomatic BPO. The incidence of complications was low with both devices. The 120-w thulium:YAG device enhances the effectiveness of Th,VEP with reeard to the oercentaee of resected tissue and the enucleation/ooeration efficiency.
文摘目的:探讨宫腔镜2μm激光治疗围绝经期功能失调性子宫出血(简称功血)的临床疗效。方法:以26例宫腔镜2μm激光子宫内膜去除术治疗的围绝经期功血患者为观察组,26例经宫腔镜子宫内膜电切术治疗的患者为对照组,对两组的手术时间、术中出血量及临床疗效进行比较。结果:观察组的手术时间明显长于对照组(16.9±4.5 min vs 13.9±3.8 min),术中出血量少于对照组(10.6±3.5 mL vs 14.2±4.2 mL),两组比较差异均有统计学意义(P<0.05);观察组总有效率为92.3%,对照组总有效率为96.2%,差异无统计学意义(P>0.05)。结论:宫腔镜2μm激光治疗围绝经期功血疗效确切,并发症少,是一种安全、简便、有效的方法,但对其长远疗效尚须进一步观察。