This paper presents an experimental study to investigate the performance of shape memory alloy(SMA) restrainers for mitigating the pounding and unseating of highway bridges when subjected to seismic excitations.Mechan...This paper presents an experimental study to investigate the performance of shape memory alloy(SMA) restrainers for mitigating the pounding and unseating of highway bridges when subjected to seismic excitations.Mechanical property tests of the SMA wire used in the restrainers are conducted first to understand the pseudo-elastic characteristics of the material.Then,a series of shaking table tests are carried out on a highway bridge model.The structural responses of the highway bridge model equipped with SMA restrainers,installed in the form of deck-deck and deck-pile connections,are analyzed and compared with the uncontrolled structures.The test results of this study indicate that the SMA restrainers are not only effective in preventing unseating but also in suppressing the seismic-induced pounding of the highway bridge model used in this study.展开更多
For years,the study of senescent cells resembled a molecular guessing game.Researchers knew these dormant cells played paradoxical roles-some secreting inflammatory signals that accelerated tissue damage,others releas...For years,the study of senescent cells resembled a molecular guessing game.Researchers knew these dormant cells played paradoxical roles-some secreting inflammatory signals that accelerated tissue damage,others releasing factors to restrain it.Yet traditional tools could only lump all senescent cells into a single category.This blindness persisted until 2024,when Dr.ZHOU Bin’s team at the Shanghai Institute of Biochemistry and Cell Biology(SIBCB).展开更多
Background:Restrained eating,often motivated by the desire to control weight,is prevalent among young female college students and is considered a risk factor for eating disorders.Negative evaluation fear,exacerbated b...Background:Restrained eating,often motivated by the desire to control weight,is prevalent among young female college students and is considered a risk factor for eating disorders.Negative evaluation fear,exacerbated by social pressure,peer comparison,and academic stress,has been identified as a potential contributor to restrained eating behavior.However,research exploring the relationship between negative evaluation fear and restrained eating,particularly in the context of self-esteem and physical appearance perfectionism,remains limited.This study aims to investigate these relationships and design an intervention program to reduce restrained eating behaviors in female college students.Methods:Study 1 involved 617 female college students,using the Physical Appearance Perfectionism Scale,Rosenberg Self-Esteem Scale,Fear of Negative Evaluation Scale,and Dutch Eating Behavior Questionnaire to measure key variables.We examined the relationships between physical appearance perfectionism,self-esteem,fear of negative evaluation,and restrained eating.In Study 2,a 4-week group psychological intervention based on Acceptance and Commitment Therapy(ACT)was implemented with 45 students,divided into experimental,control,and placebo groups.The intervention’s effectiveness was assessed in reducing restrained eating and negative evaluation fear.Results:The study found that fear of negative evaluation significantly predicted restrained eating and physical appearance perfectionism.Physical appearance perfectionism,in turn,positively predicted restrained eating and partially mediated the relationship between negative evaluation fear and restrained eating.Self-esteem moderated this mediation effect.Additionally,the ACT-based intervention significantly reduced fear of negative evaluation and restrained eating behavior in the experimental group.Conclusion:This study identifies fear of negative evaluation and physical appearance perfectionism as key predictors of restrained eating in female college students.Fear of negative evaluation significantly predicted restrained eating,with physical appearance perfectionism partially mediating this relationship.The ACT-based intervention effectively reduced both fear of negative evaluation and restrained eating.These findings highlight the importance of addressing negative evaluation fear and appearance perfectionism in interventions for restrained eating.展开更多
Over the past decade, seismically induced damage to bridges has been widely reported following major earthquakes such as the 1994 Northridge, 1995 Kobe and 1999 Chi-Chi events. Since these earthquakes, restrainers and...Over the past decade, seismically induced damage to bridges has been widely reported following major earthquakes such as the 1994 Northridge, 1995 Kobe and 1999 Chi-Chi events. Since these earthquakes, restrainers and stoppers have been installed on bridges to prevent unseating and excessive displacements, respectively. Alternatively, column jacketing has also been proven to be effective. However, the enhanced shear strength may result in extra retrofitting works on the footing. For bridges damaged in the Chi-Chi earthquake, investigations revealed that most bridge columns experienced none-to-minor damage in the longitudinal direction. The reason for this unexpected performance was the construction practice of using a rubber bearing, which is an unbolted design that may slide under large lateral forces. In this paper, parametric studies on simply-supported bridges retrofitted by a restrainer or concrete shear key along the longitudinal and transverse axes were carried out. The research focuses on finding suitable combinations of the design force and gap spacing so the restrainer and concrete shear key can be used as an unseating prevention device, with respect to the allowable column damage in terms of displacement ductility under near-fault type earthquakes. A two-lane PCI-girder bridge was selected as the benchmark model. In the longitudinal direction, a total of nine combinations considering yielding strength and gap spacing for the restrainer were analyzed; while parameters for the concrete shear key were divided into three shear force levels and three gap spacings. In the transverse direction, a similar approach was adapted, except smaller gap spacing was used. For each of the above mentioned earthquakes, seven input ground motions were selected and their PGAs were adjusted to 0.36g and 0.45g as the Design earthquake and Maximum Considerable Earthquake, respectively. Based on the results of nonlinear time history analyses, proper parameters to design the restrainers and concrete shear keys are obtained. Responses obtained from numerical simulations under the Chi-Chi earthquake leaded to new implications to design those devices. Restrainer should not exceed its breaking strain and sufficient unseating length will be needed always. Concrete Shear key was determined by considering both displacement demand of the superstructure and displacement ductility of the column at the same time. Further study is needed to provide optimal design parameters for use in performance based bridge design.展开更多
In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead ...In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model.展开更多
According to the need of popular land surface process models, characteristics and rules of some key land surface process and soil parameters over Gobi in typical arid region of Northwest China are analyzed by using th...According to the need of popular land surface process models, characteristics and rules of some key land surface process and soil parameters over Gobi in typical arid region of Northwest China are analyzed by using the data observed during the intensive observation period of the Dunhuang Land–Surface Process Field Experiment (DLSPFE) (May–June 2000). Using the relative reflection as weighting factor, the weighted mean of the surface albedo over Dunhuang Gobi in typical arid region is calculated and its values are 0.255 ± 0.021. After canceling the interference of the buildings, the mean values of the roughness length averaged with logarithm is 0.0019 ± 0.00071 m. After removing the influence of the oasis, the soil wetness factor computed with data under condition of no precipitation is 0.0045. After removing the influence of the precipitation , the mean values of the soil heat capacity over Dunhuang Gobi in typical arid region is 1.12 × 10<SUP>6</SUP> J m<SUP>−3</SUP>K<SUP>−1</SUP>, a bit smaller than the values observed in HEIFE. But the soil heat diffusivity and conductivity are about one of those observed in HEIFE. The soil water content over Dunhuang Gobi in typical synoptic condition is very little and does not exceed 1% basically.展开更多
Buckling restrained braces （BRBs） have been widely applied in seismic mitigation since they were introduced in the 1970s. However, traditional BRBs have several disadvantages caused by using a steel tube to envelope...Buckling restrained braces （BRBs） have been widely applied in seismic mitigation since they were introduced in the 1970s. However, traditional BRBs have several disadvantages caused by using a steel tube to envelope the mortar to prevent the core plate from buckling, such as： complex interfaces between the materials used, uncertain precision, and time consumption during the manufacturing processes. In this study, a new device called the multi-curve buckling restrained brace （MC-BRB） is proposed to overcome these disadvantages. The new device consists of a core plate with multiple neck portions assembled to form multiple energy dissipation segments, and the enlarged segment, lateral support elements and constraining elements to prevent the BRB from buckling. The enlarged segment located in the middle of the core plate can be welded to the lateral support and constraining elements to increase buckling resistance and to prevent them from sliding during earthquakes. Component tests and a series of shaking table tests on a full-scale steel structure equipped with MC-BRBs were carried out to investigate the behavior and capability of this new BRB design for seismic mitigation. The experimental results illustrate that the MC-BRB possesses a stable mechanical behavior under cyclic loadings and provides good protection to structures during earthquakes. Also, a mathematical model has been developed to simulate the mechanical characteristics of BRBs.展开更多
A first-order torsion theory based on Vlasov theory has been developed to investigate the restrained torsion of open thin-walled beams. The total rotation of the cross section is divided into a free warping rotation a...A first-order torsion theory based on Vlasov theory has been developed to investigate the restrained torsion of open thin-walled beams. The total rotation of the cross section is divided into a free warping rotation and a restrained shear rotation. In first-order torsion theory, St. Venant torque is only related to the free warping rotation and the expression of St. Venant torque is derived by using a semi-inverse method. The relationship between the warping torque and the restrained shear rotation is established by using an energy method. The torsion shear coefficient is then obtained. On the basis of the torsion equilibrium, the governing differential equation of the restrained torsion is derived and the corresponding initial method is given to solve the equation. The relationship between total rotation and flee warping rotation is obtained. A parameter λ, which is associated with the stiffness property of a cross section and the beam length, is introduced to determine the condition, under which the St. Venant constant is negligible. Consequently a simplified theory is derived. Numerical examples are illustrated to validate the current approach and the results of the current theory are compared with those of some other available methods. The results of comparison show that the current theory provides more accurate results, In the example of a channel-shaped cantilever beam, the applicability of the simplified theory is determined by the parameter study of λ.展开更多
Carbamoyl phosphate synthetase i （CPS1） deficiency （CPS1D） is an inborn error of the urea cycle having autosomal （2q34） recessive inheritance that can cause hyperammonemia and neonatal death or mental retardatio...Carbamoyl phosphate synthetase i （CPS1） deficiency （CPS1D） is an inborn error of the urea cycle having autosomal （2q34） recessive inheritance that can cause hyperammonemia and neonatal death or mental retardation. We analyzed the effects on CPS1 activity, kinetic parameters and enzyme stability of missense mutations reported in patients with CPS1 deficiency that map in the 20-kDa C-terminal domain of the enzyme. This domain turns on or off the enzyme depending on whether the essential allosteric activator of CPS 1, N-acetyl- L-glutamate （NAG）, is bound or is not bound to it. To carry out the present studies, we exploited a novel system that allows the expression in vitro and the purification of human CPS1, thus permitting site-directed mutagenesis. These studies have clarified disease causation by individual mutations, identifying functionally important residues, and revealing that a number of mutations decrease the affinity of the enzyme for NAG. Patients with NAG affinity-decreasing mutations might benefit from NAG site saturation therapy with N-carbamyl-L- glutamate （a registered drug, the analog of NAG）. Our results, together with additional present and prior site-directed mutagenesis data for other residues mapping in this domain, suggest an NAG-triggered conformational change in the 134-~4 loop of the C-terminal domain of this enzyme. This change might be an early event in the NAG activation process. Molecular dynamics simulations that were restrained according to the observed effects of the mutations are consistent with this hypothesis, providing further backing for this structurally plausible signaling mechanism by which NAG could trigger urea cycle activation via CPS1.展开更多
During past strong earthquakes, highway bridges have sustained severe damage or even collapse due to excessive displacements and/or very large lateral forces. For commonly used isolation bearings with a pure friction ...During past strong earthquakes, highway bridges have sustained severe damage or even collapse due to excessive displacements and/or very large lateral forces. For commonly used isolation bearings with a pure friction sliding surface, seismic forces may be reduced but displacements are often unconstrained. In this paper, an alternative seismic bearing system, called the cable-sliding friction bearing system, is developed by integrating seismic isolation devices with displacement restrainers consisting of cables attached to the upper and lower plates of the bearing. Restoring forces are provided to limit the displacements of the sliding component. Design parameters including the length and stiffness of the cables, friction coefficient, strength of the shear bolt in a fixed-type bearing, and movements under earthquake excitations are discussed. Laboratory testing of a prototype bearing subjected to vertical loads and quasi-static cyclic lateral loads, and corresponding numerical finite element simulation analysis, were carried out. It is shown that the numerical simulation shows good agreement with the experimental force-displacement hysteretic response, indicating the viability of the new bearing system. In addition, practical application of this bearing system to a multi-span bridge in China and its design advantages are discussed.展开更多
In this paper,the nonlinear parametric vibration of fluid-conveying pipes flexibly restrained at both ends and subjected to the pulsation flow excitation is investigated.The nonlinear equation of motion is derived usi...In this paper,the nonlinear parametric vibration of fluid-conveying pipes flexibly restrained at both ends and subjected to the pulsation flow excitation is investigated.The nonlinear equation of motion is derived using Hamilton^principle by considering the Kevin-Voigt viscoelastic damping,the geometric nonlinearity and the translational and rotational springs supported at the ends.The mode functions and eigen-frequencies are determined by the assumed mode method according to the elastic boundary conditions.The Galerkin method is implemented to obtain the natural frequencies and mode shapes of the pipe conveying fluid with different flow velocities.The effects of flexibly restrained conditions on stability of the pipe are analyzed.The nonlinear responses of the pipe under pulsating flow excitation are solved by the direct numerical method.The vibration behaviors are discussed in details,such as time history,frequency spectrum,phase-plane portrait,Poincare map and motion trajectory.The results show that the responses of sub-harmonic resonance and combination resonance can also be reflected in the rigidly supported pipes.The 1/5,1/8 and 1/13 sub-harmonic resonances can occur at certain excitation frequencies of the nonlinear parametric vibration system.The steady-state response amplitudes increase by a large margin and significantly affect the stability of the pipe.The effects of different spring stiffness coefficients on the parametric resonance responses are presented.For larger translational springs and rotational stiffness coefficients,the resonance frequencies shift to higher regions and the resonance amplitudes may reduce by a certain extent in accordance with the rigid-body motion.This study can provide helpful guidance on the analysis and design of piping systems subject to vibrations.展开更多
The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction...The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction method is using expansive shotcrete mixture consisting of calcium sulfoaluminate cement(CSA), ordinary Portland cement(OPC), and calcium sulfate(CS) to reduce shrinkage. Furthermore, fibers can be added to the mixture to restrain expansion and impede cracking. The objective of this paper is to study the effects of nylon fiber, glass fiber, and steel fiber on an expansive shotcrete mixture that can better resist cracking. In this study, parameters such as density, water absorption, volume of permeable voids, unconfined compressive strength(UCS), splitting tensile strength(STS), and volume change of fiber-added expansive mixtures were determined at different time periods(i.e. the strengths on the 28 th day, and the volume changes on the 1 st, 7 th, 14 th, 21 st, and 28 th days). The results show that addition of fibers can improve mixture durability, in the form of decreased water absorption and reduced permeable pore space content. Moreover, the expansion of the CSA-OPC-CS mixture was restrained up to50% by glass fiber, up to 43% by nylon fiber, and up to 28% by steel fiber. The results show that the STS was improved by 57% with glass fiber addition, 43% with steel fiber addition, and 38% with nylon fiber addition. The UCS was also increased by 31% after steel fiber addition, 26% after nylon fiber addition, and16% after glass fiber addition. These results suggest that fiber additions to the expansive shotcrete mixtures can improve durability and strengths while controlling expansion.展开更多
The local buckling of stiffened panels is one of possible failure modes and concerned by engineers in the preliminary design of lightweight structures. In practice,a simplified model,i.e.,a rectangular plate with elas...The local buckling of stiffened panels is one of possible failure modes and concerned by engineers in the preliminary design of lightweight structures. In practice,a simplified model,i.e.,a rectangular plate with elastically restrained along its unloaded edges,is established and the Ritz method is usually employed for solutions. To use the Ritz method,however,the loaded edges of the plate are usually assumed to be simply supported. An empirical correction factor has to be used to account for clamped loaded edges. Here,a simple and efficient method,called the quadrature element method(QEM),is presented for obtaining accurate buckling behavior of rectangular plates with any combinations of boundary conditions, including the elastically restrained conditions. Different from the conventional high order finite element method(FEM),non-uniformly distributed nodes are used,and thus the method can achieve an exponential rate of convergence. Formulations are worked out in detail. A computer program is developed. Improvement of solution accuracy can be easily achieved by changing the number of element nodes in the computer program. Several numerical examples are given. Results are compared with either existing solutions or finite element data for verifications. It is shown that high solution accuracy is achieved. In addition,the proposed method and developed computer program can allow quick analysis of local buckling of stiffened panels and thus is suitable for optimization routines in the preliminary design stage.展开更多
Steel frames equipped with buckling restrained braces(BRBs)have been increasingly applied in earthquake-prone areas given their excellent capacity for resisting lateral forces.Therefore,special attention has been paid...Steel frames equipped with buckling restrained braces(BRBs)have been increasingly applied in earthquake-prone areas given their excellent capacity for resisting lateral forces.Therefore,special attention has been paid to the seismic risk assessment(SRA)of such structures,e.g.,seismic fragility analysis.Conventional approaches,e.g.,nonlinear finite element simulation(NFES),are computationally inefficient for SRA analysis particularly for large-scale steel BRB frame structures.In this study,amachine learning(ML)-based seismic fragility analysis framework is established to effectively assess the risk to structures under seismic loading conditions.An optimal artificial neural network model can be trained using calculated damage and intensity measures,a technique which will be used to compute the fragility curves of a steel BRB frame instead of employing NFES.Numerical results show that a highly efficient instantaneous failure probability assessment can be made with the proposed framework for realistic large-scale building structures.展开更多
1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills ...1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills and dumpsites),which are prevalent in global cities,emit CH4 generated from the anaerobic biodegradation of municipal solid waste(MSW).Notably,the proportions of CH4 emissions from disposal sites surpass 50%of the total CH4 emissions in some megalopolises[3].CH4 has a high global warming potential(GWP),being 28 times stronger than carbon dioxide(CO_(2))over a 100-year period and 80 times stronger over a 20-year period[4].Understanding and mitigating CH4 emissions from solid waste disposal sites is particularly pertinent and pressing,considering that the latest Synthesis Report from the Intergovernmental Panel on Climate Change(IPCC)emphasizes that the current pace of mitigation and adaptation policies and measures falls short of restraining global temperature rise to under 1.5℃ within the 21st century[4].More than 150 countries signed the Global Methane Pledge at the United Nations Climate Change Conference in Glasgow(COP26),which aims to reduce global annual CH4 emissions by 30%by 2030,compared with emissions in 2020[5].展开更多
High-performance concrete （HPC） is stronger and more durable than conventional concrete. However, shrinkage and shrinkage cracking are common phenomena in HPC, especially early-age cracking. This study assessed earl...High-performance concrete （HPC） is stronger and more durable than conventional concrete. However, shrinkage and shrinkage cracking are common phenomena in HPC, especially early-age cracking. This study assessed early-age cracking of HPC for two mixtures using restrained ring tests. The two mixtures were produced with water/binder mass ratio （mw/mB） of 0.22 and 0.40, respectively. The results show that, with greater steel thickness, the higher degree of restraint resulted in a higher interface pressure and earlier cracking. With steel thickness of 6 mm, 19 mm, and 30 mm, the age of cracking were, respectively, 12 days, 8 days, and 5.4 days with the mw/mB = 0.22 mixture; and 22.5 days, 12.6 days, and 7.1 days with the mw/mB= 0.40 mixture. Cases of the same steel thickness show that the ring specimens with a thicker concrete wall crack later. With the mw/mB = 0.22 mixture, concrete walls with thicknesses of 37.5 mm, 75 mm, and 112.5 mm cracked at 3.4 days, 8.0 days, and 9.8 days, respectively; with the mw/mB = 0.40 mixture, the ages of cracking were 7.1 days, 12.6 days, and 16.0 days, respectively.展开更多
Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force...Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force is put forward by experimental method in cup-shaped drawing process. The experimental results were compared with numerical results and proved agreement. It shows the method is effective.展开更多
Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant...Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant as they affect the formation and distribution of the oil and gas in these three sub-sags.However,the differences in their tectonic evolutions and formation mechanisms have not yet been adequately explained.In this paper,stress analysis,equilibrium profiles,and paleogeomorphic restora-tion,are used to investigate the dynamic settings,formation mechanisms,and influencing factors of the structural deformation related to the formation of the Wenchang Sag based on interpretation of seismic data.The results of the stress analysis suggest clockwise deflection of the regional tensile stress direction from a WNW-ESE trend during the Early Paleocene to NW-SE and NNW-SSE trends during the Eocene,to a nearly N-S trend during the Oligocene,and finally to a NNE-SSW trend during the Miocene.This clockwise rotation of the regional tensile stress direction led to the formation of a dextral strike-slip stress component parallel to the NE-trending Zhu I South Fault.This strike-slip stress component formed a releasing bend in sub-sag A,and may be associated with the continuous subsidence of a thick sedimentary layer in sub-sag A.It also created a restraining bend in sub-sag B,which underwent multiple structural inversions during its extension and subsidence and has a relatively s mall sedimentary thick-ness.The double restraining bend in sub-sag C is considered to have been strongly uplifted and eroded in response to this strike-slip stress component.Four obvious structural inversions in sub-sag B are iden-tified in this paper.These structural inversions correspond to the last four regional tectonic movements.This interpretation suggests that the formation of the structural inversions was likely related to the strong tensile stress and the small intersection angle between the direction of the regional tensile stress and the pre-existing boundary fault.The rotation of the tensile stress direction was responsible for the strike-slip movement on the pre-existing boundary fault and the formation of the releasing bend and restraining bend,which controlled the structural evolutions of the sub-sags.This reasonably explains the differential tectonic evolution of these three sub-sags in the Wenchang Sag,and provides a crucial idea forstructuralanalysisof similarbasins.展开更多
This paper addresses the free transverse vibrations of thin simply supported nonhomogeneous isotropic rectangular plates of bilinearly varying thickness with elastically restrained edges against rotation. The Gram-Sch...This paper addresses the free transverse vibrations of thin simply supported nonhomogeneous isotropic rectangular plates of bilinearly varying thickness with elastically restrained edges against rotation. The Gram-Schmidt process has been used to generate two-dimensional boundary characteristic orthogonal polynomials, which have been used in the Rayleigh-Ritz method to study the problem. The lowest three frequencies have been computed for various values of nonhomogeneous parameters, thickness parameters, aspect ratio and flexibility parameters. A comparison of the results with those available in the literature has been made. Three-dimensional mode shapes for the specified plate have been presented.展开更多
基金Earthquake Engineering and Engineering Vibration Laboratory Foundation,Institute of Engineering Mechanics, China Earthquake Administration Under Grant No.2009a1the National Natural Science Foundation of China under Grant No.50878071
文摘This paper presents an experimental study to investigate the performance of shape memory alloy(SMA) restrainers for mitigating the pounding and unseating of highway bridges when subjected to seismic excitations.Mechanical property tests of the SMA wire used in the restrainers are conducted first to understand the pseudo-elastic characteristics of the material.Then,a series of shaking table tests are carried out on a highway bridge model.The structural responses of the highway bridge model equipped with SMA restrainers,installed in the form of deck-deck and deck-pile connections,are analyzed and compared with the uncontrolled structures.The test results of this study indicate that the SMA restrainers are not only effective in preventing unseating but also in suppressing the seismic-induced pounding of the highway bridge model used in this study.
文摘For years,the study of senescent cells resembled a molecular guessing game.Researchers knew these dormant cells played paradoxical roles-some secreting inflammatory signals that accelerated tissue damage,others releasing factors to restrain it.Yet traditional tools could only lump all senescent cells into a single category.This blindness persisted until 2024,when Dr.ZHOU Bin’s team at the Shanghai Institute of Biochemistry and Cell Biology(SIBCB).
文摘Background:Restrained eating,often motivated by the desire to control weight,is prevalent among young female college students and is considered a risk factor for eating disorders.Negative evaluation fear,exacerbated by social pressure,peer comparison,and academic stress,has been identified as a potential contributor to restrained eating behavior.However,research exploring the relationship between negative evaluation fear and restrained eating,particularly in the context of self-esteem and physical appearance perfectionism,remains limited.This study aims to investigate these relationships and design an intervention program to reduce restrained eating behaviors in female college students.Methods:Study 1 involved 617 female college students,using the Physical Appearance Perfectionism Scale,Rosenberg Self-Esteem Scale,Fear of Negative Evaluation Scale,and Dutch Eating Behavior Questionnaire to measure key variables.We examined the relationships between physical appearance perfectionism,self-esteem,fear of negative evaluation,and restrained eating.In Study 2,a 4-week group psychological intervention based on Acceptance and Commitment Therapy(ACT)was implemented with 45 students,divided into experimental,control,and placebo groups.The intervention’s effectiveness was assessed in reducing restrained eating and negative evaluation fear.Results:The study found that fear of negative evaluation significantly predicted restrained eating and physical appearance perfectionism.Physical appearance perfectionism,in turn,positively predicted restrained eating and partially mediated the relationship between negative evaluation fear and restrained eating.Self-esteem moderated this mediation effect.Additionally,the ACT-based intervention significantly reduced fear of negative evaluation and restrained eating behavior in the experimental group.Conclusion:This study identifies fear of negative evaluation and physical appearance perfectionism as key predictors of restrained eating in female college students.Fear of negative evaluation significantly predicted restrained eating,with physical appearance perfectionism partially mediating this relationship.The ACT-based intervention effectively reduced both fear of negative evaluation and restrained eating.These findings highlight the importance of addressing negative evaluation fear and appearance perfectionism in interventions for restrained eating.
文摘Over the past decade, seismically induced damage to bridges has been widely reported following major earthquakes such as the 1994 Northridge, 1995 Kobe and 1999 Chi-Chi events. Since these earthquakes, restrainers and stoppers have been installed on bridges to prevent unseating and excessive displacements, respectively. Alternatively, column jacketing has also been proven to be effective. However, the enhanced shear strength may result in extra retrofitting works on the footing. For bridges damaged in the Chi-Chi earthquake, investigations revealed that most bridge columns experienced none-to-minor damage in the longitudinal direction. The reason for this unexpected performance was the construction practice of using a rubber bearing, which is an unbolted design that may slide under large lateral forces. In this paper, parametric studies on simply-supported bridges retrofitted by a restrainer or concrete shear key along the longitudinal and transverse axes were carried out. The research focuses on finding suitable combinations of the design force and gap spacing so the restrainer and concrete shear key can be used as an unseating prevention device, with respect to the allowable column damage in terms of displacement ductility under near-fault type earthquakes. A two-lane PCI-girder bridge was selected as the benchmark model. In the longitudinal direction, a total of nine combinations considering yielding strength and gap spacing for the restrainer were analyzed; while parameters for the concrete shear key were divided into three shear force levels and three gap spacings. In the transverse direction, a similar approach was adapted, except smaller gap spacing was used. For each of the above mentioned earthquakes, seven input ground motions were selected and their PGAs were adjusted to 0.36g and 0.45g as the Design earthquake and Maximum Considerable Earthquake, respectively. Based on the results of nonlinear time history analyses, proper parameters to design the restrainers and concrete shear keys are obtained. Responses obtained from numerical simulations under the Chi-Chi earthquake leaded to new implications to design those devices. Restrainer should not exceed its breaking strain and sufficient unseating length will be needed always. Concrete Shear key was determined by considering both displacement demand of the superstructure and displacement ductility of the column at the same time. Further study is needed to provide optimal design parameters for use in performance based bridge design.
文摘In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model.
基金This research was sponsored by the National Key Program for Developing Basic Sciences Research on the Formation Mechanism and Pr
文摘According to the need of popular land surface process models, characteristics and rules of some key land surface process and soil parameters over Gobi in typical arid region of Northwest China are analyzed by using the data observed during the intensive observation period of the Dunhuang Land–Surface Process Field Experiment (DLSPFE) (May–June 2000). Using the relative reflection as weighting factor, the weighted mean of the surface albedo over Dunhuang Gobi in typical arid region is calculated and its values are 0.255 ± 0.021. After canceling the interference of the buildings, the mean values of the roughness length averaged with logarithm is 0.0019 ± 0.00071 m. After removing the influence of the oasis, the soil wetness factor computed with data under condition of no precipitation is 0.0045. After removing the influence of the precipitation , the mean values of the soil heat capacity over Dunhuang Gobi in typical arid region is 1.12 × 10<SUP>6</SUP> J m<SUP>−3</SUP>K<SUP>−1</SUP>, a bit smaller than the values observed in HEIFE. But the soil heat diffusivity and conductivity are about one of those observed in HEIFE. The soil water content over Dunhuang Gobi in typical synoptic condition is very little and does not exceed 1% basically.
基金Science Council in Chinese Taipei Under Grant No.NSC 94-2211-E-035-015
文摘Buckling restrained braces （BRBs） have been widely applied in seismic mitigation since they were introduced in the 1970s. However, traditional BRBs have several disadvantages caused by using a steel tube to envelope the mortar to prevent the core plate from buckling, such as： complex interfaces between the materials used, uncertain precision, and time consumption during the manufacturing processes. In this study, a new device called the multi-curve buckling restrained brace （MC-BRB） is proposed to overcome these disadvantages. The new device consists of a core plate with multiple neck portions assembled to form multiple energy dissipation segments, and the enlarged segment, lateral support elements and constraining elements to prevent the BRB from buckling. The enlarged segment located in the middle of the core plate can be welded to the lateral support and constraining elements to increase buckling resistance and to prevent them from sliding during earthquakes. Component tests and a series of shaking table tests on a full-scale steel structure equipped with MC-BRBs were carried out to investigate the behavior and capability of this new BRB design for seismic mitigation. The experimental results illustrate that the MC-BRB possesses a stable mechanical behavior under cyclic loadings and provides good protection to structures during earthquakes. Also, a mathematical model has been developed to simulate the mechanical characteristics of BRBs.
基金Project (No. 072012028) supported by the Science and Technology Commission of Shanghai Municipality, China
文摘A first-order torsion theory based on Vlasov theory has been developed to investigate the restrained torsion of open thin-walled beams. The total rotation of the cross section is divided into a free warping rotation and a restrained shear rotation. In first-order torsion theory, St. Venant torque is only related to the free warping rotation and the expression of St. Venant torque is derived by using a semi-inverse method. The relationship between the warping torque and the restrained shear rotation is established by using an energy method. The torsion shear coefficient is then obtained. On the basis of the torsion equilibrium, the governing differential equation of the restrained torsion is derived and the corresponding initial method is given to solve the equation. The relationship between total rotation and flee warping rotation is obtained. A parameter λ, which is associated with the stiffness property of a cross section and the beam length, is introduced to determine the condition, under which the St. Venant constant is negligible. Consequently a simplified theory is derived. Numerical examples are illustrated to validate the current approach and the results of the current theory are compared with those of some other available methods. The results of comparison show that the current theory provides more accurate results, In the example of a channel-shaped cantilever beam, the applicability of the simplified theory is determined by the parameter study of λ.
基金supported by grants from the Alicia Koplowitz Foundation, the Valencian government (No. Prometeo II/2014/ 029 to V.R.)the Spanish government (Nos. BFU2011-30407 to V.R., BFU2012-30770 to J.G. and a FPU fellowship to C.D.-F.)the Swiss National Science Foundation (No. 310030_127184 to J.H.)
文摘Carbamoyl phosphate synthetase i （CPS1） deficiency （CPS1D） is an inborn error of the urea cycle having autosomal （2q34） recessive inheritance that can cause hyperammonemia and neonatal death or mental retardation. We analyzed the effects on CPS1 activity, kinetic parameters and enzyme stability of missense mutations reported in patients with CPS1 deficiency that map in the 20-kDa C-terminal domain of the enzyme. This domain turns on or off the enzyme depending on whether the essential allosteric activator of CPS 1, N-acetyl- L-glutamate （NAG）, is bound or is not bound to it. To carry out the present studies, we exploited a novel system that allows the expression in vitro and the purification of human CPS1, thus permitting site-directed mutagenesis. These studies have clarified disease causation by individual mutations, identifying functionally important residues, and revealing that a number of mutations decrease the affinity of the enzyme for NAG. Patients with NAG affinity-decreasing mutations might benefit from NAG site saturation therapy with N-carbamyl-L- glutamate （a registered drug, the analog of NAG）. Our results, together with additional present and prior site-directed mutagenesis data for other residues mapping in this domain, suggest an NAG-triggered conformational change in the 134-~4 loop of the C-terminal domain of this enzyme. This change might be an early event in the NAG activation process. Molecular dynamics simulations that were restrained according to the observed effects of the mutations are consistent with this hypothesis, providing further backing for this structurally plausible signaling mechanism by which NAG could trigger urea cycle activation via CPS1.
基金Ministry of Science and Technology of China Under Grant No. SLDRCE09-B-08Kwang-Hua Fund for College of Civil Engineering, Tongji Universitythe National Natural Science Foundation of China Under Grants No.50978194 and No.90915011
文摘During past strong earthquakes, highway bridges have sustained severe damage or even collapse due to excessive displacements and/or very large lateral forces. For commonly used isolation bearings with a pure friction sliding surface, seismic forces may be reduced but displacements are often unconstrained. In this paper, an alternative seismic bearing system, called the cable-sliding friction bearing system, is developed by integrating seismic isolation devices with displacement restrainers consisting of cables attached to the upper and lower plates of the bearing. Restoring forces are provided to limit the displacements of the sliding component. Design parameters including the length and stiffness of the cables, friction coefficient, strength of the shear bolt in a fixed-type bearing, and movements under earthquake excitations are discussed. Laboratory testing of a prototype bearing subjected to vertical loads and quasi-static cyclic lateral loads, and corresponding numerical finite element simulation analysis, were carried out. It is shown that the numerical simulation shows good agreement with the experimental force-displacement hysteretic response, indicating the viability of the new bearing system. In addition, practical application of this bearing system to a multi-span bridge in China and its design advantages are discussed.
基金the National Natural Science Foundation of China(Grant No.51305350,Grant No.11802235)National Key Basic Research Program of China(Grant No.613268)Aeronautics Power Foundation Program of China(Grant No.6141B090320).
文摘In this paper,the nonlinear parametric vibration of fluid-conveying pipes flexibly restrained at both ends and subjected to the pulsation flow excitation is investigated.The nonlinear equation of motion is derived using Hamilton^principle by considering the Kevin-Voigt viscoelastic damping,the geometric nonlinearity and the translational and rotational springs supported at the ends.The mode functions and eigen-frequencies are determined by the assumed mode method according to the elastic boundary conditions.The Galerkin method is implemented to obtain the natural frequencies and mode shapes of the pipe conveying fluid with different flow velocities.The effects of flexibly restrained conditions on stability of the pipe are analyzed.The nonlinear responses of the pipe under pulsating flow excitation are solved by the direct numerical method.The vibration behaviors are discussed in details,such as time history,frequency spectrum,phase-plane portrait,Poincare map and motion trajectory.The results show that the responses of sub-harmonic resonance and combination resonance can also be reflected in the rigidly supported pipes.The 1/5,1/8 and 1/13 sub-harmonic resonances can occur at certain excitation frequencies of the nonlinear parametric vibration system.The steady-state response amplitudes increase by a large margin and significantly affect the stability of the pipe.The effects of different spring stiffness coefficients on the parametric resonance responses are presented.For larger translational springs and rotational stiffness coefficients,the resonance frequencies shift to higher regions and the resonance amplitudes may reduce by a certain extent in accordance with the rigid-body motion.This study can provide helpful guidance on the analysis and design of piping systems subject to vibrations.
基金financial support from Natural Sciences and Engineering ResearchCouncil(NSERC)(NSERC EGP 501335-16) along with the donated CSA cement
文摘The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction method is using expansive shotcrete mixture consisting of calcium sulfoaluminate cement(CSA), ordinary Portland cement(OPC), and calcium sulfate(CS) to reduce shrinkage. Furthermore, fibers can be added to the mixture to restrain expansion and impede cracking. The objective of this paper is to study the effects of nylon fiber, glass fiber, and steel fiber on an expansive shotcrete mixture that can better resist cracking. In this study, parameters such as density, water absorption, volume of permeable voids, unconfined compressive strength(UCS), splitting tensile strength(STS), and volume change of fiber-added expansive mixtures were determined at different time periods(i.e. the strengths on the 28 th day, and the volume changes on the 1 st, 7 th, 14 th, 21 st, and 28 th days). The results show that addition of fibers can improve mixture durability, in the form of decreased water absorption and reduced permeable pore space content. Moreover, the expansion of the CSA-OPC-CS mixture was restrained up to50% by glass fiber, up to 43% by nylon fiber, and up to 28% by steel fiber. The results show that the STS was improved by 57% with glass fiber addition, 43% with steel fiber addition, and 38% with nylon fiber addition. The UCS was also increased by 31% after steel fiber addition, 26% after nylon fiber addition, and16% after glass fiber addition. These results suggest that fiber additions to the expansive shotcrete mixtures can improve durability and strengths while controlling expansion.
基金partially supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘The local buckling of stiffened panels is one of possible failure modes and concerned by engineers in the preliminary design of lightweight structures. In practice,a simplified model,i.e.,a rectangular plate with elastically restrained along its unloaded edges,is established and the Ritz method is usually employed for solutions. To use the Ritz method,however,the loaded edges of the plate are usually assumed to be simply supported. An empirical correction factor has to be used to account for clamped loaded edges. Here,a simple and efficient method,called the quadrature element method(QEM),is presented for obtaining accurate buckling behavior of rectangular plates with any combinations of boundary conditions, including the elastically restrained conditions. Different from the conventional high order finite element method(FEM),non-uniformly distributed nodes are used,and thus the method can achieve an exponential rate of convergence. Formulations are worked out in detail. A computer program is developed. Improvement of solution accuracy can be easily achieved by changing the number of element nodes in the computer program. Several numerical examples are given. Results are compared with either existing solutions or finite element data for verifications. It is shown that high solution accuracy is achieved. In addition,the proposed method and developed computer program can allow quick analysis of local buckling of stiffened panels and thus is suitable for optimization routines in the preliminary design stage.
基金Financial support received from the Scientific Research Fund of Institute of Engineering Mechanics,China Earthquake Administration under Grant No.2019EEEVL05the National Key Research and Development Program of China under Grant No.2016YFC0701106the National Natural Science Foundation of China under Grant No.51578473 are gratefully acknowledged.
文摘Steel frames equipped with buckling restrained braces(BRBs)have been increasingly applied in earthquake-prone areas given their excellent capacity for resisting lateral forces.Therefore,special attention has been paid to the seismic risk assessment(SRA)of such structures,e.g.,seismic fragility analysis.Conventional approaches,e.g.,nonlinear finite element simulation(NFES),are computationally inefficient for SRA analysis particularly for large-scale steel BRB frame structures.In this study,amachine learning(ML)-based seismic fragility analysis framework is established to effectively assess the risk to structures under seismic loading conditions.An optimal artificial neural network model can be trained using calculated damage and intensity measures,a technique which will be used to compute the fragility curves of a steel BRB frame instead of employing NFES.Numerical results show that a highly efficient instantaneous failure probability assessment can be made with the proposed framework for realistic large-scale building structures.
基金Nanyang Technological University(NTU),Singapore,for providing research scholarships for this study.The authors thank the supports from Debris of the Anthropocene to Resources(DotA2)Lab at NTU.
文摘1.Introduction Cities are responsible for approximately 70%of all anthropogenic greenhouse gas(GHG)emissions and about 60%of all anthropogenic methane(CH4)emissions[1,2].Solid waste disposal sites(including landfills and dumpsites),which are prevalent in global cities,emit CH4 generated from the anaerobic biodegradation of municipal solid waste(MSW).Notably,the proportions of CH4 emissions from disposal sites surpass 50%of the total CH4 emissions in some megalopolises[3].CH4 has a high global warming potential(GWP),being 28 times stronger than carbon dioxide(CO_(2))over a 100-year period and 80 times stronger over a 20-year period[4].Understanding and mitigating CH4 emissions from solid waste disposal sites is particularly pertinent and pressing,considering that the latest Synthesis Report from the Intergovernmental Panel on Climate Change(IPCC)emphasizes that the current pace of mitigation and adaptation policies and measures falls short of restraining global temperature rise to under 1.5℃ within the 21st century[4].More than 150 countries signed the Global Methane Pledge at the United Nations Climate Change Conference in Glasgow(COP26),which aims to reduce global annual CH4 emissions by 30%by 2030,compared with emissions in 2020[5].
文摘High-performance concrete （HPC） is stronger and more durable than conventional concrete. However, shrinkage and shrinkage cracking are common phenomena in HPC, especially early-age cracking. This study assessed early-age cracking of HPC for two mixtures using restrained ring tests. The two mixtures were produced with water/binder mass ratio （mw/mB） of 0.22 and 0.40, respectively. The results show that, with greater steel thickness, the higher degree of restraint resulted in a higher interface pressure and earlier cracking. With steel thickness of 6 mm, 19 mm, and 30 mm, the age of cracking were, respectively, 12 days, 8 days, and 5.4 days with the mw/mB = 0.22 mixture; and 22.5 days, 12.6 days, and 7.1 days with the mw/mB= 0.40 mixture. Cases of the same steel thickness show that the ring specimens with a thicker concrete wall crack later. With the mw/mB = 0.22 mixture, concrete walls with thicknesses of 37.5 mm, 75 mm, and 112.5 mm cracked at 3.4 days, 8.0 days, and 9.8 days, respectively; with the mw/mB = 0.40 mixture, the ages of cracking were 7.1 days, 12.6 days, and 16.0 days, respectively.
基金Supported by Science and Technology Development Foundation of Shanghai (015211009).
文摘Due to complexities of draw-bead restraining force calculated according to theory and depending on sheet metal forming properties experiment testing system, a simplified method to calculate draw-bead restraining force is put forward by experimental method in cup-shaped drawing process. The experimental results were compared with numerical results and proved agreement. It shows the method is effective.
基金supported by the National Natural Science Foundation of China(Grant No.9132820142006068)Shandong Special Fund of Qingdao National Laboratory of Marine Science and Technology(No.2021QNLM020001-1).
文摘Notable differences in the structural characteristics and evolution of three adjacent sub-sags,i.e.,the Wenchang sub-sags A,B,and C,on the downthrown side of the Zhu IlI South Fault in the Wenchang Sag,are significant as they affect the formation and distribution of the oil and gas in these three sub-sags.However,the differences in their tectonic evolutions and formation mechanisms have not yet been adequately explained.In this paper,stress analysis,equilibrium profiles,and paleogeomorphic restora-tion,are used to investigate the dynamic settings,formation mechanisms,and influencing factors of the structural deformation related to the formation of the Wenchang Sag based on interpretation of seismic data.The results of the stress analysis suggest clockwise deflection of the regional tensile stress direction from a WNW-ESE trend during the Early Paleocene to NW-SE and NNW-SSE trends during the Eocene,to a nearly N-S trend during the Oligocene,and finally to a NNE-SSW trend during the Miocene.This clockwise rotation of the regional tensile stress direction led to the formation of a dextral strike-slip stress component parallel to the NE-trending Zhu I South Fault.This strike-slip stress component formed a releasing bend in sub-sag A,and may be associated with the continuous subsidence of a thick sedimentary layer in sub-sag A.It also created a restraining bend in sub-sag B,which underwent multiple structural inversions during its extension and subsidence and has a relatively s mall sedimentary thick-ness.The double restraining bend in sub-sag C is considered to have been strongly uplifted and eroded in response to this strike-slip stress component.Four obvious structural inversions in sub-sag B are iden-tified in this paper.These structural inversions correspond to the last four regional tectonic movements.This interpretation suggests that the formation of the structural inversions was likely related to the strong tensile stress and the small intersection angle between the direction of the regional tensile stress and the pre-existing boundary fault.The rotation of the tensile stress direction was responsible for the strike-slip movement on the pre-existing boundary fault and the formation of the releasing bend and restraining bend,which controlled the structural evolutions of the sub-sags.This reasonably explains the differential tectonic evolution of these three sub-sags in the Wenchang Sag,and provides a crucial idea forstructuralanalysisof similarbasins.
文摘This paper addresses the free transverse vibrations of thin simply supported nonhomogeneous isotropic rectangular plates of bilinearly varying thickness with elastically restrained edges against rotation. The Gram-Schmidt process has been used to generate two-dimensional boundary characteristic orthogonal polynomials, which have been used in the Rayleigh-Ritz method to study the problem. The lowest three frequencies have been computed for various values of nonhomogeneous parameters, thickness parameters, aspect ratio and flexibility parameters. A comparison of the results with those available in the literature has been made. Three-dimensional mode shapes for the specified plate have been presented.
