When the 2025 Intertextile Apparel Fabrics Exhibition(Autumn/Winter)was held in Shanghai,more than 3,700 top exhibitors from 26 countries and regions around the world participated.From September 2nd to 4th,the 2025&qu...When the 2025 Intertextile Apparel Fabrics Exhibition(Autumn/Winter)was held in Shanghai,more than 3,700 top exhibitors from 26 countries and regions around the world participated.From September 2nd to 4th,the 2025"Keqiao Selected"exhibition shone brightly at the event,showcasing the high-end quality of its products and the innovative strength of its regional brands.展开更多
Background Sperm cryopreservation is widely used in the cattle industry,as it allows for disassociating the localiza-tion of sires and the collection of semen from the timing of artificial insemination.While freeze-th...Background Sperm cryopreservation is widely used in the cattle industry,as it allows for disassociating the localiza-tion of sires and the collection of semen from the timing of artificial insemination.While freeze-thawing is known to impair sperm DNA integrity,whether the damage induced consists of single-(SSB)or double-strand breaks(DSB)has not been determined.In addition,no previous study has addressed if DNA breaks preferentially reside in specific genome regions such as those forming the toroid linker regions,or are rather spread throughout the regions linked to protamines.The main aim of the present work,therefore,was to elucidate the type and localization of the DNA damage generated by cryopreservation and to evaluate its impact on artificial insemination outcomes in cattle.Results The incidence of SSB and DSB was evaluated in 12 ejaculates before and after cryopreservation with the Comet assay,and the localization of the DNA breaks was assessed using pulsed-field gel electrophoresis(PFGE).Before cryopreservation,the incidence of SSB was 10.99%±4.62%and involved 20.56%±3.04%of sperm cells,whereas these figures significantly(P<0.0001)increased up to 34.11%±3.48%and 53.36%±11.00%in frozen-thawed sperm.In contrast,no significant differences in the incidence of DSB were observed(P>0.990)before and after cryopreservation(before:incidence of 13.91%±1.75%of sperm DNA affecting 56.04%±12.49%of sperm cells;after:incidence of 13.55%±1.55%of sperm DNA involving 53.36%±11.00%of sperm cells).Moreover,PFGE revealed that the percentage of sperm DNA fragments whose length was shorter than a toroid(<31.5 kb)was greater(P<0.0001)after(27.00%±4.26%)than before freeze-thawing(15.57%±4.53%).These differences indicated that the DNA breaks induced by cryopreservation affect the regions condensed in protamines,which are structured in toroids.On the other hand,in vivo fertility rates were associated to the incidence of SSB and DSB in frozen-thawed sperm(P=0.032 and P=0.005),but not with the size of the DNA fragments resulting from these breaks(P>0.05).Conclusion Cryopreservation of bovine sperm generates single-strand DNA breaks,which are mainly located in protamine-condensed toroidal regions.The incidence of DNA breaks in cryopreserved sperm has an impact on cat-tle fertility,regardless of the size of generated fragments.展开更多
Surface albedo,as one of the important properties of the underlying surface,has a significant impact on the surface energy balance in cold regions.However,due to the complexity of the factors affecting surface albedo,...Surface albedo,as one of the important properties of the underlying surface,has a significant impact on the surface energy balance in cold regions.However,due to the complexity of the factors affecting surface albedo,existing calculations still contain inaccuracies.Therefore,this study conducted surface albedo experiments on loess with different water contents and temperatures.By analyzing the surface albedo measurements of samples with varying temperature and water content levels,as well as the soil freezing characteristic curve(SFCC)and soil-water characteristic curve(SWCC)of loess,the study explores the influence of soil temperature and water content on the surface albedo of loess.The results indicate that both the temperature and water content of loess jointly affect surface albedo.During the process of albedo change,there exists a water content threshold that alters the trend of surface albedo.Soil temperature influences surface albedo by affecting the content of pore ice and liquid water within the soil.When the water content of loess is relatively low,the surface albedo decreases as the unfrozen water content decreases.However,this trend changes as the water content of loess increases.Additionally,a decrease in soil temperature lowers the moisture content threshold during the changes in surface albedo.This study provides a reference for exploring and determining the surface energy balance in cold regions under the background of warm and humid climates,as well as for establishing thermal calculation boundaries.展开更多
BACKGROUND Metabolomics sequencing technology was used to investigate the changes of intestinal flora and metabolites in gastric cancer patients in plateau areas.AIM To investigate changes in gut microbiota and their ...BACKGROUND Metabolomics sequencing technology was used to investigate the changes of intestinal flora and metabolites in gastric cancer patients in plateau areas.AIM To investigate changes in gut microbiota and their metabolites in patients with gastric cancer from plateau regions using untargeted metabolomic sequencing.METHODS Fresh morning fecal samples were collected from 30 gastric cancer patients diagnosed at a tertiary hospital in Qinghai Province and 30 healthy individuals(controls).Liquid chromatography-tandem mass spectrometry based untargeted metabolomic sequencing was used to analyze metabolite changes and predict metabolic function.RESULTS Metabolomic analysis identified 281 metabolites in samples from both groups.These metabolites were categorized into eight major classes,listed in descending order of abundance:Lipids and lipid-like molecules(35.443%);organic acids and derivatives(29.114%);organic oxygen compounds(15.19%);nucleosides,nucleotides,and analogs(13.924%);organoheterocyclic compounds(2.532%),amino acids and peptides(1.266%);benzenoids(1.266%);and fatty acids(1.266%).Compared with the control group,the top 10 metabolites elevated in the gastric cancer group included:Dethiobiotin,glycylproline,glycine,hydroxyisocaproic acid,tyramine,methionine sulfoxide,5-aminopentanoic acid,citrulline,betonicine,and formiminoglutamic acid and the top 10 decreased were:Cytidine,5'-methylthioadenosine,trehalose,melibiose,lotaustralin,adenosine,inosine,ribothymidine,raffinose,and galactinol.Functional prediction analysis revealed that these differential metabolites were primarily enriched in 12 metabolic pathways,including purine metabolism,cysteine and methionine metabolism,galactose metabolism,lysine degradation,glycine,serine,and threonine metabolism,biotin metabolism,pyrimidine metabolism,arginine and proline metabolism,histidine metabolism,primary bile acid biosynthesis,starch and sucrose metabolism,and tyrosine metabolism.CONCLUSION Significant differences in intestinal microbial metabolites and associated metabolic pathways were observed between gastric cancer patients and healthy controls residing in plateau regions.展开更多
Branch length and branch diameter are important characteristics that determine wood quality and yield.Development of static branch length and diameter models by incorporating individual tree variables,site quality and...Branch length and branch diameter are important characteristics that determine wood quality and yield.Development of static branch length and diameter models by incorporating individual tree variables,site quality and competition have been widely studied,while the climate effect has rarely been reported.In this study,mixed-effects climate-sensitive branch length and diameter models were developed based on 228 sample trees of Larix kaempferi from three latitude regions in China(approximate 42°N in Liaoning Province,33°N in Gansu Province,and 30°N in Hubei Province).Results revealed that diameter at breast height,and crown ratio,sum of the basal areas of trees larger than the subject trees,dominant tree height,mean warmest month temperature,and summer precipitation substantially improved branch length model.Diameter at breast height,and crown ratio,ratio of the sum of DBH in sample plot to the subject tree,dominant tree height,mean warmest month temperature,and spring precipitation significantly improved branch diameter model.Compared with base model,mean square error reduction of mixed-effects branch length and diameter models were 32.9%and 44.1%,respectively.The relative contributions of covariates to branch length model were tree size(59.1%),site quality(25.7%),competition(13.5%),and climate(1.7%),and branch diameter model were tree size(57.0%),competition(21.9%),site quality(18.3%),and climate(2.8%).Relative contributions of covariates on branch length and diameter models from different latitude regions were different.Effects of competition on branch length model in Liaoning and Hubei were larger than climate,whereas climate in Gansu was larger than competition.As for branch diameter model,competition in Liaoning was larger than site quality,whereas site quality in Hubei and Gansu was larger than competition.The present study strengthened the importance of considering climate variables in developing branch length and diameter model.It is desirable to disentangle the different sources of variations in affecting branch length and diameter from different latitude regions to reduce the uncertainty in predicting branch characteristics under the condition of climate changing.展开更多
Objective:To analyze the risk of osteoporosis among middle-aged men in the cold regions of China(Heilongjiang Province)and provide theoretical support for the early identification of high-risk populations.Methods:Bone...Objective:To analyze the risk of osteoporosis among middle-aged men in the cold regions of China(Heilongjiang Province)and provide theoretical support for the early identification of high-risk populations.Methods:Bone mineral density(BMD)data were collected from male subjects aged 50-65 who met the inclusion criteria at the physical examination center of a hospital in Harbin between August to December 2022.General clinical data and dietary information were obtained through face-to-face interviews using a dietary questionnaire survey.Results:The prevalence of osteoporosis and osteopenia was 14.38%and 52.06%,respectively,while normal bone mass accounted for 33.56%.Significant differences were observed among groups in smoking habits,sunlight exposure,exercise levels,and dietary patterns at each bone mass level.The BMD of the lumbar spine,femoral neck,and hip showed a negative correlation with the Dietary Inflammatory Index(DII)score.Multivariate logistic regression analysis revealed that smoking and a diet high in oil and salt were positively associated with the risk of osteoporosis.A pro-inflammatory diet was also positively correlated with osteoporosis risk,with individuals in this group being 7.723 times more likely to develop osteoporosis compared to those in the anti-inflammatory diet group.Conclusion:The high prevalence of osteoporosis and osteopenia observed in this study highlighted that osteoporosis is a significant and pressing issue among middle-aged men.Smoking,limited sunlight exposure,reduced physical activity,diets high in oil and salt,and pro-inflammatory diets were identified as major risk factors for bone loss.These factors are closely linked to the geography,climate,and cultural practices of cold regions in China.Primary healthcare in this region should focus on the screening and prevention of osteoporosis in middle-aged men by promoting smoking cessation,increased sunlight exposure,adequate vitamin D supplementation,regular physical activity,and adherence to a healthy diet to maintain bone health.展开更多
Before nationwide implementation of waste classification programs in rural areas,identifying suitable pilot regions is crucial.This study develops a comprehensive framework for assessing and selecting these pilot regi...Before nationwide implementation of waste classification programs in rural areas,identifying suitable pilot regions is crucial.This study develops a comprehensive framework for assessing and selecting these pilot regions.Data were collected through 654 valid questionnaires and interviews with respondents from rural areas in six provinces across China.Primary assessment criteria included disposal methods for kitchen waste,recyclables,hazardous waste,and residual waste,as well as farmers’willingness to separate hazardous waste when offered compensation and the impact of centralized waste treatment in villages.Secondary criteria focused on disposal methods for agrochemical packages and other hazardous waste.Using the weighted sum of squares method,the study evaluated the suitability of six regions as pilot areas for waste classification.The results identified villages in Jiangsu province and Hebei province as the most suitable pilot regions.Based on the findings,the study provides recommendations to address weaknesses in these regions to enhance the effectiveness of future trials and offers tailored suggestions for other regions to improve their waste classification initiatives.展开更多
Climate change and human activities have led to desertification and decreased land productivity,significantly affecting human livelihoods in desert regions.Identifying suitable areas for cultivating economic and nativ...Climate change and human activities have led to desertification and decreased land productivity,significantly affecting human livelihoods in desert regions.Identifying suitable areas for cultivating economic and native plants based on ecological capacity,biological restoration,and risk management can be valuable tools for combating desertification.In this study,we identified suitable areas for the growth of economic and medicinal Moringa peregrina trees in desert regions of Sistan and Baluchestan Province,southern Iran,using library research and field methods.We also assessed the economic involvement of local communities in areas under different topographic conditions(namely flat area,undulating area,rolling area,moderately sloping area,and steep area)in the study area.Financial indicators such as the net present value(NPV),benefit-cost ratio(BCR),internal rate of return(IRR),and return on investment(ROI)were calculated for areas under various topographic conditions in the study area.The rolling area with results of NPV(6142.75 USD),IRR(103.38),BCR(5.38),and ROI(in the 3rd year)was the best region for investing and cultivating M.peregrina.The minimum economic level varied from 0.80 hm2 in the flat area to 21.60 hm2 in the steep area.Also,approximately 5,314,629.51 hm2 of desert lands in the study area were deemed suitable for M.peregrina cultivation,benefiting around 1,743,246 households in the study area.Cultivating M.peregrina in southern Iran can positively affect local communities and help preserve land from erosion.Our study will provide theoretical support for planting native species in other degraded desert regions to enhance ecosystem services and the well-being of indigenous populations.展开更多
Permanently shadowed regions(PSRs)on the Moon are potential reservoirs for water ice,making them hot spots for future lunar exploration.The water ice in PSRs would cause distinctive changes in space weathering there,i...Permanently shadowed regions(PSRs)on the Moon are potential reservoirs for water ice,making them hot spots for future lunar exploration.The water ice in PSRs would cause distinctive changes in space weathering there,in particular reduction-oxidation processes that diff er from those in illuminated regions.To determine the characteristics of products formed during space weathering in PSRs,the lunar meteorite NWA 10203 with artifi cially added water was irradiated with a nanosecond laser to simulate a micro-meteorite bombardment of lunar soil containing water ice.The TEM results of the water-incorporated sample showed distinct amorphous rims that exhibited irregular thickness,poor stratifi cation,the appearance of bubbles,and a reduced number of npFe^(0).Additionally,EELS analysis showed the presence of ferric iron at the rim of the nanophase metallic iron particles(npFe^(0))in the amorphous rim with the involvement of water.The results suggest that water ice is another possible factor contributing to oxidation during micrometeorite bombardment on the lunar surface.In addition,it off ers a reference for a new space weathering model that incorporates water in PSRs,which could be widespread on asteroids with volatiles.展开更多
The spatial distribution of overburden layer thickness(OLT)is crucial for landslide susceptibility prediction and slope stability analysis.Due to OLT spatial heterogeneity in hillslope regions,combined with the diffic...The spatial distribution of overburden layer thickness(OLT)is crucial for landslide susceptibility prediction and slope stability analysis.Due to OLT spatial heterogeneity in hillslope regions,combined with the difficulty and time consumption of OLT sample collection,accurately predicting OLT distribution remains a challenging.To address this,a novel framework has been developed.First,OLT samples are collected through field surveys,remote sensing,and geological drilling.Next,the heterogeneity of OLT’s spatial distribution is analyzed using the probability distribution of OLT samples and their horizontal and vertical distributions.The OLT samples are categorized and the small sample categories are expanded using the synthetic minority over-sampling technique(SMOTE).The slope position is selected as a key conditioning factor.Subsequently,16 conditioning factors are applied to construct OLT prediction model using the random forest regression algorithm.Weights are assigned to each OLT sample category to balance the uneven distribution of sample sizes.Finally,the Pearson correlation coefficient,mean absolute error(MAE),root mean square error(RMSE),and Lin’s concordance correlation coefficient(Lin’s CCC)are employed to validate the OLT prediction results.The Huangtan town serves as the case study.Results show:(1)heterogeneity analysis,SMOTE-based OLT sample expansion strategy and slope position selection can significantly mitigate the effect of spatial heterogeneity on OLT prediction.(2)The Pearson correlation coefficient,RMSE,MAE and Lin’s CCC values are 0.84,1.173,1.378 and 0.804,respectively,indicating excellent prediction performance.This research provides an effective solution for predicting OLT distribution in hillslope regions.展开更多
Background:This study aimed to evaluate the prognostic value of the lymphocyte-to-monocyte ratio(LMR)and cancer antigen 724(CA724)in patients with proximal gastric cancer residing in cold climate regions.Methods:A ret...Background:This study aimed to evaluate the prognostic value of the lymphocyte-to-monocyte ratio(LMR)and cancer antigen 724(CA724)in patients with proximal gastric cancer residing in cold climate regions.Methods:A retrospective analysis was conducted on 313 patients diagnosed with proximal gastric cancer in cold climate regions between 2014 and 2017.Preoperative hematological markers,including LMR and CA724,were assessed.Receiver operating characteristic(ROC)curves were used to determine optimal cutoff values,which were then combined to form the LMR+CA724 score.Statistical analyses included Kaplan-Meier survival curves,log-rank tests,and Cox proportional hazards regression.Results:A high preoperative LMR+CA724 score was significantly associated with older age,advanced pTNM stage,vascular invasion,and elevated levels of NMPVR,NMR,and AAR.The LMR+CA724 score demonstrated a higher area under the curve(AUC)compared to LMR or CA724 alone.Multivariate analysis identified pTNM stage,Borrmann type,histological type,and the LMR+CA724 score as independent prognostic factors for overall survival(OS).A nomogram incorporating these four variables achieved an AUC of 0.817,indicating strong predictive performance.Conclusion:The LMR+CA724 score is a reliable and independent prognostic indicator for patients with proximal gastric cancer in cold climate regions.Its integration into clinical practice may support treatment planning and long-term management by enhancing personalized care.Further prospective studies are warranted to validate these findings in broader and more diverse patient populations.展开更多
Cropland abandonment has become a global issue that poses significant threats to sustainable cropland management,national food security,and the ecological environment.Remote sensing technology is crucial for identifyi...Cropland abandonment has become a global issue that poses significant threats to sustainable cropland management,national food security,and the ecological environment.Remote sensing technology is crucial for identifying and monitoring abandoned cropland in large-scale areas.However,limited information is available on the effective identification methods and spatial distribution patterns of abandoned cropland in the hilly and gully regions.This study introduced two methods-the land-use trajectory and normalized difference vegetation index(NDVI)time series-for monitoring abandoned cropland and evaluating its spatial distribution in Yanhe River Basin using Landsat-8 images from 2019 to 2021.The results showed that using a random forest algorithm,high-precision annual land-use classifications were achieved with the generation of reliable land-cover samples and an optimized feature dataset.The overall accuracy(OA)and Kappa coefficient of the land-use maps exceeded 90% and 0.88,respectively,demonstrating the effectiveness of the classification over three years.These two distinct change detection methods were used to identify abandoned cropland in the study area,and their accuracy and effectiveness were evaluated.The land-use trajectory method performed better than the NDVI time series method for extracting abandoned cropland,with an OA of 83.5% and an F1 score of 84.7%.According to the land-use trajectory detection results,the study area had 164.6 km^(2) of abandoned cropland area in 2021,with an abandonment rate of 16.3%.Furthermore,cropland abandonment mainly occurred in the northwestern part of the region,which has harsh natural conditions,while abandonment was rare in the southern and eastern regions.Topography and landforms significantly influenced the spatial distribution of abandoned cropland,with most abandoned cropland located in mountainous regions with higher elevations and steeper slopes.The abandonment rate generally increased with the elevation and slope.These findings provide valuable references and guidance for selecting appropriate methods to identify abandoned cropland and analyze its spatial distribution in the hilly and gully regions.Our proposed methods offer robust solutions for monitoring abandoned cropland and optimizing land-use change detection in similar regions with complex landforms.展开更多
Climate change poses substantial challenges to agricultural productivity and sustainability,particularly in Mediterranean and Sub-Saharan Africa regions.Local smallholder farmers’adaptation strategies to climate chan...Climate change poses substantial challenges to agricultural productivity and sustainability,particularly in Mediterranean and Sub-Saharan Africa regions.Local smallholder farmers’adaptation strategies to climate change are crucial for mitigating these impacts.Therefore,this study investigated the socioeconomic factors influencing smallholder farmers’perceptions and adaptation strategies to climate change in four countries(Morocco,Egypt,Italy,and Senegal)of Mediterranean and Sub-Saharan Africa regions using a binary logistic regression(BLR)model.The results indicated that educational level,farming experience,agricultural income,farm size,participation in agricultural workshops,and training in Good Agricultural Practices(GAPs)significantly impacted smallholder farmers’perceptions and adaptation strategies to climate change(such as smallholder farmers adopting drought-tolerant crops).Higher educational level was linked to the greater possibility of smallholder farmers adopting drought-tolerant crops in Italy and Egypt,while gaps in rural education limited the possibility of smallholder farmers adopting drought-tolerant crops in Morocco and Senegal.Farming experience and agricultural income also enhanced the possibility of smallholder farmers adopting drought-tolerant crops,with notable variations across countries due to systemic barriers such as limited infrastructure in Senegal.Larger farm size and participation in agricultural workshops further improved the possibility of smallholder farmers adopting drought-tolerant crops,particularly in Morocco and Egypt.The findings highlighted the importance of tailored interventions and policy measures to support smallholder farmers in effectively responding to the challenges of climate change under diverse agricultural contexts.By understanding the specific needs and circumstances of smallholder farmers in these countries,policymakers can develop more effective adaptation strategies to enhance agricultural resilience and sustainability under the context of climate change.展开更多
The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is a...The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is applied to analyze the livelihood transition in the economic system and conversion of traditional knowledge in the creative system for farm households engaged in large cardamom cultivation in Northern mountainous region in Vietnam.This study used a probit model to examine a data set comprising 300 households and confirmed that factors within the social and physical systems(such as labor,access to information,social networks,land use,and transportation infrastructure)determined livelihood transition to tourism employment within the economic system.In addition,the conversion of traditional knowledge in the creative system was found to be contingent upon non-farm employment and credit capital in the economic system,as well as traditional knowledge and knowledge exchange in the knowledge system.This study demonstrates how the sustainable development of rural agriculture can be achieved by converting traditional knowledge and transferring livelihood,contributing to attain Sustainable Development Goals 2(Zero Hunger)and SDG 12(Responsible Consumption and Production).展开更多
Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opp...Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opportunities.Despite the complexity and typicality of Chinese mountainous ethnic minority regions in terms of eco-cultural tourism and land use dynamics,the interplay among tourism development,land use changes,and landscape ecological risk in these specific contexts has received insufficient attention.To explore how eco-cultural tourism development in ethnic minority mountainous regions affects land use and landscape ecology,this study investigates the evolution of land use in Southeast Guizhou Province from 1980-2020,integrating GIS spatial analysis,the landscape pattern index and landscape ecological risk index analysis.Over the past four decades(1980-2020),eco-cultural tourism has driven significant land use transformations characterized by substantial expansion of building land,growth of ecological land(notably forest land and water areas),and reduction of cultivated land.Concurrently,landscape ecological risk evolved through distinct phases-showing an overall increase during 1980-2000 with expanding medium-risk zones,followed by stabilization from 2000-2020.Tourism development accelerated these land transitions while fostering multifunctional compound land uses,enhancing both land value and utilization efficiency.Crucially,eco-cultural tourism in ethnic regions demonstrates capacity to reconcile ecological conservation with economic development,providing transferable models for similar regions globally.展开更多
Objective:Effective Chronic Kidney Disease(CKD)management is particularly important in cold regions of China,where climate and lifestyle factors play significant roles.However,there is a lack of relevant studies in th...Objective:Effective Chronic Kidney Disease(CKD)management is particularly important in cold regions of China,where climate and lifestyle factors play significant roles.However,there is a lack of relevant studies in this area.Therefore,the purpose of this study was:(1)to assess the status of self-management capacity in individuals with CKD in cold regions of China and analyze the factors influencing it;(2)to identify strategies to improve CKD management in primary care settings in these regions;and(3)to understand patients'attitudes toward eHealth services.Methods:This was a regional,cross-sectional observational study.A questionnaire measuring CKD patients'self-management abilities was derived from the Perceived Kidney Disease Self-Management Scale,the Kidney Disease Behavioral Inventory(KDBI),and the Health Literacy Questionnaire.Data were collected from hospitalized CKD patients in Heilongjiang Province and analyzed using One-Way Analysis of Variance(ANOVA),Hierarchical Regression Analysis,and K-prototype cluster analysis.Results:A total of 957 participants were tested.Of these,70.64%had less than a bachelor's degree,and 56.27%had been diagnosed with hypertensive or diabetic nephropathy.The KDBI scale showed a lower overall score compared to the PKDSMS.Factors such as CKD stage 4(F=2.367,P=0.042),last year's medical expenses(F=3.974,P=0.004),and poor self-rated health(F=33.352,P<0.01)were found to influence scores on both scales.The health literacy questionnaire revealed significant differences(P<0.01)in health knowledge,except by sex.Additionally,healthcare expenditures and poor self-rated health were negatively associated with self-management capacity.Conclusion:This study provides valuable insights into the self-management challenges faced by CKD patients in cold regions of China.Despite some difficulties in improving self-management,patients showed positive attitudes toward enhancing CKD management services in primary care and developing digital management tools.These findings offer useful references and recommendations for future clinical practice and research in this field.展开更多
The distribution of igneous rocks is closely related to hydrocarbon resources.This study utilized high-precision gravity,magnetic,and rock physical property data,employing gravity-magnetic field fusion technology and ...The distribution of igneous rocks is closely related to hydrocarbon resources.This study utilized high-precision gravity,magnetic,and rock physical property data,employing gravity-magnetic field fusion technology and Euler deconvolution technology.The objective was to identify the distribution of igneous rocks in the China Seas and neighboring regions and investigate their relationships with petroliferous basins.Our results reveal that igneous rocks are widely scattered throughout the China Seas and neighboring regions,with the highest concentration in the northwest(NW)and the second highest concentration in the east-northeast(ENE).The largest-scale igneous rocks are those with a north-south(N-S)orientation,followed by those with northeast(NE),NW,and ENE orientations.The depths of igneous rocks within petroliferous basins typically range from 3 km to 9 km and are associated with hydrocarbon resource distributions characterized by deep oil and shallow gas.The proportions of igneous rocks in different types of basins exhibit varying correlations with the total hydrocarbon resources.In particular,the proportion of igneous rocks in rift-type basins in the China Seas exhibits a strong linear correlation with the total hydrocarbon resources.These research findings provide valuable guidance for studying the relationship between igneous rock distribution and petroliferous basins,offering insights that can inform future hydrocarbon exploration endeavors.展开更多
Background:Vestibular migraine(VM)is a common disorder characterized by recurrent dizziness or vertigo,often aggravated by cold exposure.This study aimed to identify differentially expressed circular RNAs(circRNAs)in ...Background:Vestibular migraine(VM)is a common disorder characterized by recurrent dizziness or vertigo,often aggravated by cold exposure.This study aimed to identify differentially expressed circular RNAs(circRNAs)in cold-region VM and explore the underlying molecular mechanisms.Methods:Peripheral blood samples from long-term residents of Heilongjiang Province profiled by circRNA microarray,and differentially expressed circRNAs were validated by quantitative reverse transcription polymerase chain reaction(qRT-PCR).A competing endogenous RNA(ceRNA)network and enriched pathways were inferred by bioinformatics.A VM-like mouse model was established using nitroglycerin(NTG)and kainic acid(KA)and confirmed by behavioral testing and western blot.The hsa_circ_0003201/miR-31-5p/triggering receptor expressed on myeloid cells 2(TREM2)axis and related pathways were examined in clinical samples and in the trigeminal nucleus caudalis(TNC)and vestibular nuclei(VN)of mice using qRT-PCR,enzyme-linked immunosorbent assay(ELISA),and western blot.CircRNA microarray profiling also compared expression patterns between VM and migraine patients.Results:Hsa_circ_0003201 was significantly upregulated in cold-region VM patients.Bioinformatic analyses revealed that hsa_circ_0003201 may regulate the miR-31-5p/TREM2 axis and be associated with phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling,pyruvate metabolism,and transient receptor potential(TRP)pathways.Clinical validation confirmed increased hsa_circ_0003201 and TREM2 and decreased miR-31-5p.VM-like mice exhibited central sensitization and vestibular dysfunction,with increased TREM2,decreased miR-31-5p,and PI3K/AKT activation in the TNC and VN.Comparative circRNA analysis between VM and migraine patients indicated distinct expression patterns.Conclusion:Hsa_circ_0003201 shows potential as a diagnostic biomarker for cold-region VM,and the hsa_circ_0003201/miR-31-5p/TREM2 axis may contribute to pathogenesis through PI3K/AKT signaling,pyruvate metabolism,and TRP-related pathways.展开更多
This article explores the styles and characteristics of thematic art creation in Hong Kong,Macao,and Taiwan regions,analyzing the uniqueness of these regions’artistic backgrounds,artistic languages,theme selections,a...This article explores the styles and characteristics of thematic art creation in Hong Kong,Macao,and Taiwan regions,analyzing the uniqueness of these regions’artistic backgrounds,artistic languages,theme selections,and expressive techniques.The art creation in Hong Kong,Macao,and Taiwan regions is deeply influenced by traditional Chinese culture while incorporating Western artistic elements,exhibiting a diversified artistic style.Thematic art creation in these three regions has its own distinct features,including a deep exploration of local culture and a sensitive capture of the spirit of the times,which together constitute a rich and colorful artistic landscape in Hong Kong,Macao,and Taiwan regions.展开更多
文摘When the 2025 Intertextile Apparel Fabrics Exhibition(Autumn/Winter)was held in Shanghai,more than 3,700 top exhibitors from 26 countries and regions around the world participated.From September 2nd to 4th,the 2025"Keqiao Selected"exhibition shone brightly at the event,showcasing the high-end quality of its products and the innovative strength of its regional brands.
基金Ministry of Science,Innovation and Universities,Spain(NextGeneration EU fundsMaría Zambrano Program 124/MTAI/22+2 种基金and PID2020-113320RB-I00)Agency for Management of University and Research Grants,Regional Government of Catalonia,Spain(2021-SGR-00900)Catalan Institution for Research and Advanced Studies(ICREA).
文摘Background Sperm cryopreservation is widely used in the cattle industry,as it allows for disassociating the localiza-tion of sires and the collection of semen from the timing of artificial insemination.While freeze-thawing is known to impair sperm DNA integrity,whether the damage induced consists of single-(SSB)or double-strand breaks(DSB)has not been determined.In addition,no previous study has addressed if DNA breaks preferentially reside in specific genome regions such as those forming the toroid linker regions,or are rather spread throughout the regions linked to protamines.The main aim of the present work,therefore,was to elucidate the type and localization of the DNA damage generated by cryopreservation and to evaluate its impact on artificial insemination outcomes in cattle.Results The incidence of SSB and DSB was evaluated in 12 ejaculates before and after cryopreservation with the Comet assay,and the localization of the DNA breaks was assessed using pulsed-field gel electrophoresis(PFGE).Before cryopreservation,the incidence of SSB was 10.99%±4.62%and involved 20.56%±3.04%of sperm cells,whereas these figures significantly(P<0.0001)increased up to 34.11%±3.48%and 53.36%±11.00%in frozen-thawed sperm.In contrast,no significant differences in the incidence of DSB were observed(P>0.990)before and after cryopreservation(before:incidence of 13.91%±1.75%of sperm DNA affecting 56.04%±12.49%of sperm cells;after:incidence of 13.55%±1.55%of sperm DNA involving 53.36%±11.00%of sperm cells).Moreover,PFGE revealed that the percentage of sperm DNA fragments whose length was shorter than a toroid(<31.5 kb)was greater(P<0.0001)after(27.00%±4.26%)than before freeze-thawing(15.57%±4.53%).These differences indicated that the DNA breaks induced by cryopreservation affect the regions condensed in protamines,which are structured in toroids.On the other hand,in vivo fertility rates were associated to the incidence of SSB and DSB in frozen-thawed sperm(P=0.032 and P=0.005),but not with the size of the DNA fragments resulting from these breaks(P>0.05).Conclusion Cryopreservation of bovine sperm generates single-strand DNA breaks,which are mainly located in protamine-condensed toroidal regions.The incidence of DNA breaks in cryopreserved sperm has an impact on cat-tle fertility,regardless of the size of generated fragments.
基金supported by the National Natural Science Foundation of China(42261028)the Chinese Academy of Sciences“Light of West China”Program for Western Young Scholars(23JR6KA027)+3 种基金the Science Foundation for Distinguished Young Scholars of Gansu Province(24JRRA167)the Key Research and Development Program on Ecological Civilization Construction of Gansu Province(25YFFA012)Gansu Provincial Science and Technology Plan Fund Project(24CXGA063)Scientific Research Projects on Ecological and Environmental Protection in Heilongjiang Province in 2023(Grant No.:HST2023ZR005)。
文摘Surface albedo,as one of the important properties of the underlying surface,has a significant impact on the surface energy balance in cold regions.However,due to the complexity of the factors affecting surface albedo,existing calculations still contain inaccuracies.Therefore,this study conducted surface albedo experiments on loess with different water contents and temperatures.By analyzing the surface albedo measurements of samples with varying temperature and water content levels,as well as the soil freezing characteristic curve(SFCC)and soil-water characteristic curve(SWCC)of loess,the study explores the influence of soil temperature and water content on the surface albedo of loess.The results indicate that both the temperature and water content of loess jointly affect surface albedo.During the process of albedo change,there exists a water content threshold that alters the trend of surface albedo.Soil temperature influences surface albedo by affecting the content of pore ice and liquid water within the soil.When the water content of loess is relatively low,the surface albedo decreases as the unfrozen water content decreases.However,this trend changes as the water content of loess increases.Additionally,a decrease in soil temperature lowers the moisture content threshold during the changes in surface albedo.This study provides a reference for exploring and determining the surface energy balance in cold regions under the background of warm and humid climates,as well as for establishing thermal calculation boundaries.
基金Supported by Gansu Provincial Natural Science Foundation Project,No.23JRRA725Postgraduate Research Innovation Project of Northwest Minzu University in 2025,No.31920250001-382024 Qinghai Province's"Kunlun Talent High-end Innovative and Entrepreneurial Talent Project"Cultivates Top Talents Project,No.QHKLYC-GDCXCY-2024-155.
文摘BACKGROUND Metabolomics sequencing technology was used to investigate the changes of intestinal flora and metabolites in gastric cancer patients in plateau areas.AIM To investigate changes in gut microbiota and their metabolites in patients with gastric cancer from plateau regions using untargeted metabolomic sequencing.METHODS Fresh morning fecal samples were collected from 30 gastric cancer patients diagnosed at a tertiary hospital in Qinghai Province and 30 healthy individuals(controls).Liquid chromatography-tandem mass spectrometry based untargeted metabolomic sequencing was used to analyze metabolite changes and predict metabolic function.RESULTS Metabolomic analysis identified 281 metabolites in samples from both groups.These metabolites were categorized into eight major classes,listed in descending order of abundance:Lipids and lipid-like molecules(35.443%);organic acids and derivatives(29.114%);organic oxygen compounds(15.19%);nucleosides,nucleotides,and analogs(13.924%);organoheterocyclic compounds(2.532%),amino acids and peptides(1.266%);benzenoids(1.266%);and fatty acids(1.266%).Compared with the control group,the top 10 metabolites elevated in the gastric cancer group included:Dethiobiotin,glycylproline,glycine,hydroxyisocaproic acid,tyramine,methionine sulfoxide,5-aminopentanoic acid,citrulline,betonicine,and formiminoglutamic acid and the top 10 decreased were:Cytidine,5'-methylthioadenosine,trehalose,melibiose,lotaustralin,adenosine,inosine,ribothymidine,raffinose,and galactinol.Functional prediction analysis revealed that these differential metabolites were primarily enriched in 12 metabolic pathways,including purine metabolism,cysteine and methionine metabolism,galactose metabolism,lysine degradation,glycine,serine,and threonine metabolism,biotin metabolism,pyrimidine metabolism,arginine and proline metabolism,histidine metabolism,primary bile acid biosynthesis,starch and sucrose metabolism,and tyrosine metabolism.CONCLUSION Significant differences in intestinal microbial metabolites and associated metabolic pathways were observed between gastric cancer patients and healthy controls residing in plateau regions.
基金funded by the National Key Research and Development Program of China(2023YFD2200801)National Natural Science Foundation of China(No.32471864)+1 种基金the Science&Technology Project for Excellent Young Scholars of Liaoning Province(2024JH3/10200036)Liao Ning Revitalization Talents Program(No.XLYC2403180).
文摘Branch length and branch diameter are important characteristics that determine wood quality and yield.Development of static branch length and diameter models by incorporating individual tree variables,site quality and competition have been widely studied,while the climate effect has rarely been reported.In this study,mixed-effects climate-sensitive branch length and diameter models were developed based on 228 sample trees of Larix kaempferi from three latitude regions in China(approximate 42°N in Liaoning Province,33°N in Gansu Province,and 30°N in Hubei Province).Results revealed that diameter at breast height,and crown ratio,sum of the basal areas of trees larger than the subject trees,dominant tree height,mean warmest month temperature,and summer precipitation substantially improved branch length model.Diameter at breast height,and crown ratio,ratio of the sum of DBH in sample plot to the subject tree,dominant tree height,mean warmest month temperature,and spring precipitation significantly improved branch diameter model.Compared with base model,mean square error reduction of mixed-effects branch length and diameter models were 32.9%and 44.1%,respectively.The relative contributions of covariates to branch length model were tree size(59.1%),site quality(25.7%),competition(13.5%),and climate(1.7%),and branch diameter model were tree size(57.0%),competition(21.9%),site quality(18.3%),and climate(2.8%).Relative contributions of covariates on branch length and diameter models from different latitude regions were different.Effects of competition on branch length model in Liaoning and Hubei were larger than climate,whereas climate in Gansu was larger than competition.As for branch diameter model,competition in Liaoning was larger than site quality,whereas site quality in Hubei and Gansu was larger than competition.The present study strengthened the importance of considering climate variables in developing branch length and diameter model.It is desirable to disentangle the different sources of variations in affecting branch length and diameter from different latitude regions to reduce the uncertainty in predicting branch characteristics under the condition of climate changing.
文摘Objective:To analyze the risk of osteoporosis among middle-aged men in the cold regions of China(Heilongjiang Province)and provide theoretical support for the early identification of high-risk populations.Methods:Bone mineral density(BMD)data were collected from male subjects aged 50-65 who met the inclusion criteria at the physical examination center of a hospital in Harbin between August to December 2022.General clinical data and dietary information were obtained through face-to-face interviews using a dietary questionnaire survey.Results:The prevalence of osteoporosis and osteopenia was 14.38%and 52.06%,respectively,while normal bone mass accounted for 33.56%.Significant differences were observed among groups in smoking habits,sunlight exposure,exercise levels,and dietary patterns at each bone mass level.The BMD of the lumbar spine,femoral neck,and hip showed a negative correlation with the Dietary Inflammatory Index(DII)score.Multivariate logistic regression analysis revealed that smoking and a diet high in oil and salt were positively associated with the risk of osteoporosis.A pro-inflammatory diet was also positively correlated with osteoporosis risk,with individuals in this group being 7.723 times more likely to develop osteoporosis compared to those in the anti-inflammatory diet group.Conclusion:The high prevalence of osteoporosis and osteopenia observed in this study highlighted that osteoporosis is a significant and pressing issue among middle-aged men.Smoking,limited sunlight exposure,reduced physical activity,diets high in oil and salt,and pro-inflammatory diets were identified as major risk factors for bone loss.These factors are closely linked to the geography,climate,and cultural practices of cold regions in China.Primary healthcare in this region should focus on the screening and prevention of osteoporosis in middle-aged men by promoting smoking cessation,increased sunlight exposure,adequate vitamin D supplementation,regular physical activity,and adherence to a healthy diet to maintain bone health.
基金supported by the Yunnan Provincial Education Department Scientific Research Fund Project(Grant No.2022J0525).
文摘Before nationwide implementation of waste classification programs in rural areas,identifying suitable pilot regions is crucial.This study develops a comprehensive framework for assessing and selecting these pilot regions.Data were collected through 654 valid questionnaires and interviews with respondents from rural areas in six provinces across China.Primary assessment criteria included disposal methods for kitchen waste,recyclables,hazardous waste,and residual waste,as well as farmers’willingness to separate hazardous waste when offered compensation and the impact of centralized waste treatment in villages.Secondary criteria focused on disposal methods for agrochemical packages and other hazardous waste.Using the weighted sum of squares method,the study evaluated the suitability of six regions as pilot areas for waste classification.The results identified villages in Jiangsu province and Hebei province as the most suitable pilot regions.Based on the findings,the study provides recommendations to address weaknesses in these regions to enhance the effectiveness of future trials and offers tailored suggestions for other regions to improve their waste classification initiatives.
基金funded by the Chinese Academy of Sciences President's International Fellowship Initiative(2024VCC0009).
文摘Climate change and human activities have led to desertification and decreased land productivity,significantly affecting human livelihoods in desert regions.Identifying suitable areas for cultivating economic and native plants based on ecological capacity,biological restoration,and risk management can be valuable tools for combating desertification.In this study,we identified suitable areas for the growth of economic and medicinal Moringa peregrina trees in desert regions of Sistan and Baluchestan Province,southern Iran,using library research and field methods.We also assessed the economic involvement of local communities in areas under different topographic conditions(namely flat area,undulating area,rolling area,moderately sloping area,and steep area)in the study area.Financial indicators such as the net present value(NPV),benefit-cost ratio(BCR),internal rate of return(IRR),and return on investment(ROI)were calculated for areas under various topographic conditions in the study area.The rolling area with results of NPV(6142.75 USD),IRR(103.38),BCR(5.38),and ROI(in the 3rd year)was the best region for investing and cultivating M.peregrina.The minimum economic level varied from 0.80 hm2 in the flat area to 21.60 hm2 in the steep area.Also,approximately 5,314,629.51 hm2 of desert lands in the study area were deemed suitable for M.peregrina cultivation,benefiting around 1,743,246 households in the study area.Cultivating M.peregrina in southern Iran can positively affect local communities and help preserve land from erosion.Our study will provide theoretical support for planting native species in other degraded desert regions to enhance ecosystem services and the well-being of indigenous populations.
基金support from the Youth Innovation Promotion Association,Chinese Academy of Sciences(2020395)Strategic Priority Research Program of the Chinese Academy of Sciences grant XDB 41000000(Y.L.)+4 种基金National Natural Science Foundation of China(Nos.42273042 and 41931077)"From 0 to 1"Original Exploration Cultivation Project,Institute of Geochemistry,Chinese Academy of Sciences(DHSZZ2023-3)Guizhou Provincial Foundation for Excellent Scholars Program(No.GCC[2023]088)Guizhou Provincial Science and Technology Projects:QKHJCZK[2023]-General 473NSFC Young Scientist Fund(Nos.42303041 and 42403043)。
文摘Permanently shadowed regions(PSRs)on the Moon are potential reservoirs for water ice,making them hot spots for future lunar exploration.The water ice in PSRs would cause distinctive changes in space weathering there,in particular reduction-oxidation processes that diff er from those in illuminated regions.To determine the characteristics of products formed during space weathering in PSRs,the lunar meteorite NWA 10203 with artifi cially added water was irradiated with a nanosecond laser to simulate a micro-meteorite bombardment of lunar soil containing water ice.The TEM results of the water-incorporated sample showed distinct amorphous rims that exhibited irregular thickness,poor stratifi cation,the appearance of bubbles,and a reduced number of npFe^(0).Additionally,EELS analysis showed the presence of ferric iron at the rim of the nanophase metallic iron particles(npFe^(0))in the amorphous rim with the involvement of water.The results suggest that water ice is another possible factor contributing to oxidation during micrometeorite bombardment on the lunar surface.In addition,it off ers a reference for a new space weathering model that incorporates water in PSRs,which could be widespread on asteroids with volatiles.
基金funded by the Natural Science Foundation of China(No.42407241,42272326 and 52222905)Jiangxi Provincial Natural Science Foundation(Nos.20242BAB20241,20242BAB23052 and 20242BAB24001).
文摘The spatial distribution of overburden layer thickness(OLT)is crucial for landslide susceptibility prediction and slope stability analysis.Due to OLT spatial heterogeneity in hillslope regions,combined with the difficulty and time consumption of OLT sample collection,accurately predicting OLT distribution remains a challenging.To address this,a novel framework has been developed.First,OLT samples are collected through field surveys,remote sensing,and geological drilling.Next,the heterogeneity of OLT’s spatial distribution is analyzed using the probability distribution of OLT samples and their horizontal and vertical distributions.The OLT samples are categorized and the small sample categories are expanded using the synthetic minority over-sampling technique(SMOTE).The slope position is selected as a key conditioning factor.Subsequently,16 conditioning factors are applied to construct OLT prediction model using the random forest regression algorithm.Weights are assigned to each OLT sample category to balance the uneven distribution of sample sizes.Finally,the Pearson correlation coefficient,mean absolute error(MAE),root mean square error(RMSE),and Lin’s concordance correlation coefficient(Lin’s CCC)are employed to validate the OLT prediction results.The Huangtan town serves as the case study.Results show:(1)heterogeneity analysis,SMOTE-based OLT sample expansion strategy and slope position selection can significantly mitigate the effect of spatial heterogeneity on OLT prediction.(2)The Pearson correlation coefficient,RMSE,MAE and Lin’s CCC values are 0.84,1.173,1.378 and 0.804,respectively,indicating excellent prediction performance.This research provides an effective solution for predicting OLT distribution in hillslope regions.
基金supported by the Postdoctoral Scientific Research Development Fund of Heilongjiang Province,2020(Grant No.LBH-Q20157).
文摘Background:This study aimed to evaluate the prognostic value of the lymphocyte-to-monocyte ratio(LMR)and cancer antigen 724(CA724)in patients with proximal gastric cancer residing in cold climate regions.Methods:A retrospective analysis was conducted on 313 patients diagnosed with proximal gastric cancer in cold climate regions between 2014 and 2017.Preoperative hematological markers,including LMR and CA724,were assessed.Receiver operating characteristic(ROC)curves were used to determine optimal cutoff values,which were then combined to form the LMR+CA724 score.Statistical analyses included Kaplan-Meier survival curves,log-rank tests,and Cox proportional hazards regression.Results:A high preoperative LMR+CA724 score was significantly associated with older age,advanced pTNM stage,vascular invasion,and elevated levels of NMPVR,NMR,and AAR.The LMR+CA724 score demonstrated a higher area under the curve(AUC)compared to LMR or CA724 alone.Multivariate analysis identified pTNM stage,Borrmann type,histological type,and the LMR+CA724 score as independent prognostic factors for overall survival(OS).A nomogram incorporating these four variables achieved an AUC of 0.817,indicating strong predictive performance.Conclusion:The LMR+CA724 score is a reliable and independent prognostic indicator for patients with proximal gastric cancer in cold climate regions.Its integration into clinical practice may support treatment planning and long-term management by enhancing personalized care.Further prospective studies are warranted to validate these findings in broader and more diverse patient populations.
基金supported by the National Key R&D Program of China(2023YFD1900300)the State Administration of Foreign Experts Affairs of China(B12007)+1 种基金the 111 Project of Chinathe support by the China Scholarship Council(202306300092).
文摘Cropland abandonment has become a global issue that poses significant threats to sustainable cropland management,national food security,and the ecological environment.Remote sensing technology is crucial for identifying and monitoring abandoned cropland in large-scale areas.However,limited information is available on the effective identification methods and spatial distribution patterns of abandoned cropland in the hilly and gully regions.This study introduced two methods-the land-use trajectory and normalized difference vegetation index(NDVI)time series-for monitoring abandoned cropland and evaluating its spatial distribution in Yanhe River Basin using Landsat-8 images from 2019 to 2021.The results showed that using a random forest algorithm,high-precision annual land-use classifications were achieved with the generation of reliable land-cover samples and an optimized feature dataset.The overall accuracy(OA)and Kappa coefficient of the land-use maps exceeded 90% and 0.88,respectively,demonstrating the effectiveness of the classification over three years.These two distinct change detection methods were used to identify abandoned cropland in the study area,and their accuracy and effectiveness were evaluated.The land-use trajectory method performed better than the NDVI time series method for extracting abandoned cropland,with an OA of 83.5% and an F1 score of 84.7%.According to the land-use trajectory detection results,the study area had 164.6 km^(2) of abandoned cropland area in 2021,with an abandonment rate of 16.3%.Furthermore,cropland abandonment mainly occurred in the northwestern part of the region,which has harsh natural conditions,while abandonment was rare in the southern and eastern regions.Topography and landforms significantly influenced the spatial distribution of abandoned cropland,with most abandoned cropland located in mountainous regions with higher elevations and steeper slopes.The abandonment rate generally increased with the elevation and slope.These findings provide valuable references and guidance for selecting appropriate methods to identify abandoned cropland and analyze its spatial distribution in the hilly and gully regions.Our proposed methods offer robust solutions for monitoring abandoned cropland and optimizing land-use change detection in similar regions with complex landforms.
基金an integral component of the TRUSTFARM Project,supported by the European Union’s Horizon 2020 research and innovation programThe TRUSTFARM Project was carried out under the European Research Area Network Cofund on Food Systems and Climate(ERA-NET FOSC,862555)+1 种基金built upon and supported by the experience from the Joint Programming Initiative on Agriculture,Food Security&Climate Change(FACCE-JPI)the European Research Area Network Cofund on Long-term Europe-Africa Partnership on Agricultural Research for Development(LEAP-Agri).
文摘Climate change poses substantial challenges to agricultural productivity and sustainability,particularly in Mediterranean and Sub-Saharan Africa regions.Local smallholder farmers’adaptation strategies to climate change are crucial for mitigating these impacts.Therefore,this study investigated the socioeconomic factors influencing smallholder farmers’perceptions and adaptation strategies to climate change in four countries(Morocco,Egypt,Italy,and Senegal)of Mediterranean and Sub-Saharan Africa regions using a binary logistic regression(BLR)model.The results indicated that educational level,farming experience,agricultural income,farm size,participation in agricultural workshops,and training in Good Agricultural Practices(GAPs)significantly impacted smallholder farmers’perceptions and adaptation strategies to climate change(such as smallholder farmers adopting drought-tolerant crops).Higher educational level was linked to the greater possibility of smallholder farmers adopting drought-tolerant crops in Italy and Egypt,while gaps in rural education limited the possibility of smallholder farmers adopting drought-tolerant crops in Morocco and Senegal.Farming experience and agricultural income also enhanced the possibility of smallholder farmers adopting drought-tolerant crops,with notable variations across countries due to systemic barriers such as limited infrastructure in Senegal.Larger farm size and participation in agricultural workshops further improved the possibility of smallholder farmers adopting drought-tolerant crops,particularly in Morocco and Egypt.The findings highlighted the importance of tailored interventions and policy measures to support smallholder farmers in effectively responding to the challenges of climate change under diverse agricultural contexts.By understanding the specific needs and circumstances of smallholder farmers in these countries,policymakers can develop more effective adaptation strategies to enhance agricultural resilience and sustainability under the context of climate change.
文摘The study offers a conceptual framework illuminating sustainable rural development by a continuous cycling interplay among five interdependent systems,physical,social,economic,knowledge,and creative.The framework is applied to analyze the livelihood transition in the economic system and conversion of traditional knowledge in the creative system for farm households engaged in large cardamom cultivation in Northern mountainous region in Vietnam.This study used a probit model to examine a data set comprising 300 households and confirmed that factors within the social and physical systems(such as labor,access to information,social networks,land use,and transportation infrastructure)determined livelihood transition to tourism employment within the economic system.In addition,the conversion of traditional knowledge in the creative system was found to be contingent upon non-farm employment and credit capital in the economic system,as well as traditional knowledge and knowledge exchange in the knowledge system.This study demonstrates how the sustainable development of rural agriculture can be achieved by converting traditional knowledge and transferring livelihood,contributing to attain Sustainable Development Goals 2(Zero Hunger)and SDG 12(Responsible Consumption and Production).
基金supported by the National Social Science Foundation of China(Grant No.20CMZ033)Fundamental Research Funds for the Central Universities(CCNU24ZZ125).
文摘Mountainous minority regions in China,characterized by abundant natural and cultural resources,ecologically fragile environments,and often geographically remote locations,pose distinct developmental challenges and opportunities.Despite the complexity and typicality of Chinese mountainous ethnic minority regions in terms of eco-cultural tourism and land use dynamics,the interplay among tourism development,land use changes,and landscape ecological risk in these specific contexts has received insufficient attention.To explore how eco-cultural tourism development in ethnic minority mountainous regions affects land use and landscape ecology,this study investigates the evolution of land use in Southeast Guizhou Province from 1980-2020,integrating GIS spatial analysis,the landscape pattern index and landscape ecological risk index analysis.Over the past four decades(1980-2020),eco-cultural tourism has driven significant land use transformations characterized by substantial expansion of building land,growth of ecological land(notably forest land and water areas),and reduction of cultivated land.Concurrently,landscape ecological risk evolved through distinct phases-showing an overall increase during 1980-2000 with expanding medium-risk zones,followed by stabilization from 2000-2020.Tourism development accelerated these land transitions while fostering multifunctional compound land uses,enhancing both land value and utilization efficiency.Crucially,eco-cultural tourism in ethnic regions demonstrates capacity to reconcile ecological conservation with economic development,providing transferable models for similar regions globally.
基金supported by the Natural Science Foundation of China(7247042122)the Key Research and Development Project of Heilongjiang Province,China(2024ZX12C06).
文摘Objective:Effective Chronic Kidney Disease(CKD)management is particularly important in cold regions of China,where climate and lifestyle factors play significant roles.However,there is a lack of relevant studies in this area.Therefore,the purpose of this study was:(1)to assess the status of self-management capacity in individuals with CKD in cold regions of China and analyze the factors influencing it;(2)to identify strategies to improve CKD management in primary care settings in these regions;and(3)to understand patients'attitudes toward eHealth services.Methods:This was a regional,cross-sectional observational study.A questionnaire measuring CKD patients'self-management abilities was derived from the Perceived Kidney Disease Self-Management Scale,the Kidney Disease Behavioral Inventory(KDBI),and the Health Literacy Questionnaire.Data were collected from hospitalized CKD patients in Heilongjiang Province and analyzed using One-Way Analysis of Variance(ANOVA),Hierarchical Regression Analysis,and K-prototype cluster analysis.Results:A total of 957 participants were tested.Of these,70.64%had less than a bachelor's degree,and 56.27%had been diagnosed with hypertensive or diabetic nephropathy.The KDBI scale showed a lower overall score compared to the PKDSMS.Factors such as CKD stage 4(F=2.367,P=0.042),last year's medical expenses(F=3.974,P=0.004),and poor self-rated health(F=33.352,P<0.01)were found to influence scores on both scales.The health literacy questionnaire revealed significant differences(P<0.01)in health knowledge,except by sex.Additionally,healthcare expenditures and poor self-rated health were negatively associated with self-management capacity.Conclusion:This study provides valuable insights into the self-management challenges faced by CKD patients in cold regions of China.Despite some difficulties in improving self-management,patients showed positive attitudes toward enhancing CKD management services in primary care and developing digital management tools.These findings offer useful references and recommendations for future clinical practice and research in this field.
基金The National Key Research and Development Program of China under contract No.2017YFC0602202.
文摘The distribution of igneous rocks is closely related to hydrocarbon resources.This study utilized high-precision gravity,magnetic,and rock physical property data,employing gravity-magnetic field fusion technology and Euler deconvolution technology.The objective was to identify the distribution of igneous rocks in the China Seas and neighboring regions and investigate their relationships with petroliferous basins.Our results reveal that igneous rocks are widely scattered throughout the China Seas and neighboring regions,with the highest concentration in the northwest(NW)and the second highest concentration in the east-northeast(ENE).The largest-scale igneous rocks are those with a north-south(N-S)orientation,followed by those with northeast(NE),NW,and ENE orientations.The depths of igneous rocks within petroliferous basins typically range from 3 km to 9 km and are associated with hydrocarbon resource distributions characterized by deep oil and shallow gas.The proportions of igneous rocks in different types of basins exhibit varying correlations with the total hydrocarbon resources.In particular,the proportion of igneous rocks in rift-type basins in the China Seas exhibits a strong linear correlation with the total hydrocarbon resources.These research findings provide valuable guidance for studying the relationship between igneous rock distribution and petroliferous basins,offering insights that can inform future hydrocarbon exploration endeavors.
基金supported by General Program of National Natural Science Foundation of China(No.82071549,82371483)Key Research&Development Program of Heilongjiang(No.2023ZX06C02)Youth Foundation of the first Affiliated Hospital of Harbin Medical University(No.2024YQ22).
文摘Background:Vestibular migraine(VM)is a common disorder characterized by recurrent dizziness or vertigo,often aggravated by cold exposure.This study aimed to identify differentially expressed circular RNAs(circRNAs)in cold-region VM and explore the underlying molecular mechanisms.Methods:Peripheral blood samples from long-term residents of Heilongjiang Province profiled by circRNA microarray,and differentially expressed circRNAs were validated by quantitative reverse transcription polymerase chain reaction(qRT-PCR).A competing endogenous RNA(ceRNA)network and enriched pathways were inferred by bioinformatics.A VM-like mouse model was established using nitroglycerin(NTG)and kainic acid(KA)and confirmed by behavioral testing and western blot.The hsa_circ_0003201/miR-31-5p/triggering receptor expressed on myeloid cells 2(TREM2)axis and related pathways were examined in clinical samples and in the trigeminal nucleus caudalis(TNC)and vestibular nuclei(VN)of mice using qRT-PCR,enzyme-linked immunosorbent assay(ELISA),and western blot.CircRNA microarray profiling also compared expression patterns between VM and migraine patients.Results:Hsa_circ_0003201 was significantly upregulated in cold-region VM patients.Bioinformatic analyses revealed that hsa_circ_0003201 may regulate the miR-31-5p/TREM2 axis and be associated with phosphoinositide 3-kinase(PI3K)/protein kinase B(AKT)signaling,pyruvate metabolism,and transient receptor potential(TRP)pathways.Clinical validation confirmed increased hsa_circ_0003201 and TREM2 and decreased miR-31-5p.VM-like mice exhibited central sensitization and vestibular dysfunction,with increased TREM2,decreased miR-31-5p,and PI3K/AKT activation in the TNC and VN.Comparative circRNA analysis between VM and migraine patients indicated distinct expression patterns.Conclusion:Hsa_circ_0003201 shows potential as a diagnostic biomarker for cold-region VM,and the hsa_circ_0003201/miR-31-5p/TREM2 axis may contribute to pathogenesis through PI3K/AKT signaling,pyruvate metabolism,and TRP-related pathways.
文摘This article explores the styles and characteristics of thematic art creation in Hong Kong,Macao,and Taiwan regions,analyzing the uniqueness of these regions’artistic backgrounds,artistic languages,theme selections,and expressive techniques.The art creation in Hong Kong,Macao,and Taiwan regions is deeply influenced by traditional Chinese culture while incorporating Western artistic elements,exhibiting a diversified artistic style.Thematic art creation in these three regions has its own distinct features,including a deep exploration of local culture and a sensitive capture of the spirit of the times,which together constitute a rich and colorful artistic landscape in Hong Kong,Macao,and Taiwan regions.
