分析急性生理与慢性健康评分(APACHE-Ⅱ评分)、红细胞体积分布宽度(red cell volume distribution width,RDW)及氨基末端脑利钠肽前体(NT-proBNP)与脓毒症患者预后的相关性。选取72例脓毒症患者作为研究对象,患者的入院时间为2022年1月...分析急性生理与慢性健康评分(APACHE-Ⅱ评分)、红细胞体积分布宽度(red cell volume distribution width,RDW)及氨基末端脑利钠肽前体(NT-proBNP)与脓毒症患者预后的相关性。选取72例脓毒症患者作为研究对象,患者的入院时间为2022年1月—2023年12月,按照存活与否将患者分为存活组(n=58)和病亡组(n=14),对比存活组与病亡组患者的APACHE-Ⅱ评分、RDW及NT-proBNP指标。结果显示,存活组与病亡组脓毒症患者的APACHE-Ⅱ评分、RDW及NT-proBNP差异显著,存活组脓毒症患者的APACHE-Ⅱ评分、RDW及NT-proBNP更优,差异有统计学意义(P<0.05)。BNP浓度越高,APACHE-Ⅱ评分越高,BNP浓度与APACHE-Ⅱ评分成正比。研究发现,APACHE-Ⅱ评分、RDW及NT-proB-NP与脓毒症患者的预后具有相关性。展开更多
在临床实践中,诊断和预后评估通常依赖多种实验室和评分指标。近年来,红细胞分布宽度(RDW)、中性粒细胞与淋巴细胞比值(NLR)和红细胞分布宽度与血小板计数比值(RPR)作为新兴复合实验室指标,在疾病诊断和预后评估中展现出显著价值。尤其...在临床实践中,诊断和预后评估通常依赖多种实验室和评分指标。近年来,红细胞分布宽度(RDW)、中性粒细胞与淋巴细胞比值(NLR)和红细胞分布宽度与血小板计数比值(RPR)作为新兴复合实验室指标,在疾病诊断和预后评估中展现出显著价值。尤其是在急性疾病中,这些指标因其快速获得的特性而备受关注。文章综述了RDW和RPR在脑卒中、急性心肌梗死、冠状动脉介入治疗、脓毒症及恶性肿瘤中的最新研究进展,强调其在预测疾病严重程度和预后中的潜力。研究表明,RDW和RPR作为早期获取的指标,能够有效评估上述疾病患者的病情演变和预后。其进一步研究有望推动这些指标在临床中的广泛应用。In clinical practice, diagnosis and prognosis assessment often rely on various laboratory and scoring indices. In recent years, emerging composite laboratory indices such as red blood cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and the ratio of red blood cell distribution width to platelet count (RPR) have demonstrated significant value in disease diagnosis and prognosis evaluation. Particularly in acute diseases, these indices have gained attention due to their rapid availability. This review summarizes the latest research on RDW and RPR in conditions such as stroke, acute myocardial infarction, coronary artery interventions, sepsis, and malignancies, highlighting their potential in predicting disease severity and outcomes. Studies indicate that RDW and RPR, as early accessible markers, can effectively evaluate disease progression and prognosis in these patients. Further research is expected to promote the widespread clinical application of these indices.展开更多
目的:探讨急性非静脉曲张性上消化道出血(ANVUGIB)患者红细胞分布宽度(RDW)、D二聚体(D-D)、S100钙结合蛋白12(S100A12)与病情和临床结局的关系。方法:选择2021年7月至2023年8月贵阳市第一人民医院收治的ANVUGIB患者184例作为研究组,同...目的:探讨急性非静脉曲张性上消化道出血(ANVUGIB)患者红细胞分布宽度(RDW)、D二聚体(D-D)、S100钙结合蛋白12(S100A12)与病情和临床结局的关系。方法:选择2021年7月至2023年8月贵阳市第一人民医院收治的ANVUGIB患者184例作为研究组,同期体检健康者100例作为对照组。根据Rockall危险积分将患者分为低危组(28例)、中危组(60例)、高危组(96例),根据住院期间临床结局将患者分为预后不良组(66例)和预后良好组(118例)。检测RDW、血浆D-D、血清S100A12水平。采用多因素Logistic回归分析ANVUGIB患者临床结局不良的危险因素。结果:研究组RDW、血浆D-D、血清S100A12水平高于对照组(P<0.05)。高危组RDW、血浆D-D、血清S100A12水平显著高于中危组、低危组,中危组RDW、血浆D-D、血清S100A12水平显著高于低危组(P<0.05)。结局不良组患者RDW、血浆D-D、血清S100A12水平高于结局良好组(P<0.05)。多因素Logsitic回归分析显示,Rockall危险积分升高、出血量>1000 m L、RDW升高、血浆D-D升高、血清S100A12升高是ANVUGIB患者临床结局不良的危险因素(P<0.05)。结论:ANVUGIB患者RDW、D-D、S100A12水平与患者病情和临床结局密切相关,RDW升高、血浆D-D升高、血清S100A12升高是ANVUGIB患者临床结局不良的危险因素。展开更多
目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12...目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12月期间在我院就诊的66例急性上消化道出血患者的临床资料,根据其入院时病情严重情况分为严重组(失血量≥750 mL,n=41)和非严重组(失血量<750 mL,n=25)。比较入院时两组患者血乳酸、RDW、PDW等指标水平,采用受试者工作特征(Receiver operating characteristic,ROC)曲线分析入院时血乳酸、RDW、PDW对急性上消化道出血患者的诊断效能。入院后30 d,根据快速序贯器官功能衰竭评估(Quick sequential organ failure assessment,qSOFA)评分将患者分为预后不良组(qSOFA≥1分)和预后良好组(qSOFA<1分)两亚组,比较两亚组患者入院后30 d血乳酸、RDW、PDW水平和qSOFA评分的关系。结果:入院时,严重组的血乳酸、RDW、PDW水平显著高于非严重组(P<0.05),血乳酸、RDW、PDW水平三者单一指标检测的ROC曲线下面积(Area under the ROC curve,AUC)值分别是0.861、0.769、0.763,差异具有统计学意义(P<0.05)。预后不良组入院时的血乳酸、RDW、PDW水平显著高于预后良好组(P<0.05),Pearson相关系数分析显示,血乳酸、RDW、PDW水平和qSOFA评分具有相关性。结论:血乳酸、RDW、PDW与急性上消化道出血患者预后密切相关,可以提供重要的诊断和治疗参考,帮助改善患者的预后和治疗效果。展开更多
Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of childr...Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of children with asthma.Methods:Fifty-five children with suspected asthma were admitted to the hospital from July 2021 to July 2023.They underwent a bronchodilator test upon admission and their RDW,PDW,and IgE were detected.The efficacy of diagnosis with a single indicator(RDW/PDW/IgE)and combined parameters(PDW+PDW+IgE)were compared with the results of the bronchodilator test.Results:49 cases of pediatric asthma were diagnosed by the bronchodilator test.RDW and PDW of asthmatic children were lower than those of non-asthmatic children,while the IgE of asthmatic children was higher than that of non-asthmatic children,and there was a significant difference in the RDW,PDW,and IgE among children with different degrees of asthma severity(P<0.05).The positive rate of the three combined diagnostic tests of RDW,PDW,and IgE was significantly higher than the positive rate of a single-parameter diagnosis(P<0.05).Conclusion:The combination of RDW,PDW,and IgE plays a crucial role in the clinical diagnosis of asthmatic children.These tests further improve the efficiency of clinical diagnosis and help identify the severity of the disease.展开更多
Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acut...Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 60 elderly AECOPD patients were enrolled and divided into embolus group(12 cases)and thrombus group(48 cases)according to whether they were combined with pulmonary embolism and the MLPR,NLR,and RDW values of the two groups were determined respectively.Results:The patients in the two groups had different degrees of vascular structural and functional abnormalities,and the MLPR,NLR,and RDW in the embolus group were significantly higher than those in the thrombus group(P<0.05);while the differences in NLR and RDW between the two groups were not significant.Conclusion:MLPR,NLR,and RDW can provide an objective basis for assessing PE in elderly AECOPD patients.展开更多
文摘分析急性生理与慢性健康评分(APACHE-Ⅱ评分)、红细胞体积分布宽度(red cell volume distribution width,RDW)及氨基末端脑利钠肽前体(NT-proBNP)与脓毒症患者预后的相关性。选取72例脓毒症患者作为研究对象,患者的入院时间为2022年1月—2023年12月,按照存活与否将患者分为存活组(n=58)和病亡组(n=14),对比存活组与病亡组患者的APACHE-Ⅱ评分、RDW及NT-proBNP指标。结果显示,存活组与病亡组脓毒症患者的APACHE-Ⅱ评分、RDW及NT-proBNP差异显著,存活组脓毒症患者的APACHE-Ⅱ评分、RDW及NT-proBNP更优,差异有统计学意义(P<0.05)。BNP浓度越高,APACHE-Ⅱ评分越高,BNP浓度与APACHE-Ⅱ评分成正比。研究发现,APACHE-Ⅱ评分、RDW及NT-proB-NP与脓毒症患者的预后具有相关性。
文摘在临床实践中,诊断和预后评估通常依赖多种实验室和评分指标。近年来,红细胞分布宽度(RDW)、中性粒细胞与淋巴细胞比值(NLR)和红细胞分布宽度与血小板计数比值(RPR)作为新兴复合实验室指标,在疾病诊断和预后评估中展现出显著价值。尤其是在急性疾病中,这些指标因其快速获得的特性而备受关注。文章综述了RDW和RPR在脑卒中、急性心肌梗死、冠状动脉介入治疗、脓毒症及恶性肿瘤中的最新研究进展,强调其在预测疾病严重程度和预后中的潜力。研究表明,RDW和RPR作为早期获取的指标,能够有效评估上述疾病患者的病情演变和预后。其进一步研究有望推动这些指标在临床中的广泛应用。In clinical practice, diagnosis and prognosis assessment often rely on various laboratory and scoring indices. In recent years, emerging composite laboratory indices such as red blood cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and the ratio of red blood cell distribution width to platelet count (RPR) have demonstrated significant value in disease diagnosis and prognosis evaluation. Particularly in acute diseases, these indices have gained attention due to their rapid availability. This review summarizes the latest research on RDW and RPR in conditions such as stroke, acute myocardial infarction, coronary artery interventions, sepsis, and malignancies, highlighting their potential in predicting disease severity and outcomes. Studies indicate that RDW and RPR, as early accessible markers, can effectively evaluate disease progression and prognosis in these patients. Further research is expected to promote the widespread clinical application of these indices.
文摘目的:探讨急性非静脉曲张性上消化道出血(ANVUGIB)患者红细胞分布宽度(RDW)、D二聚体(D-D)、S100钙结合蛋白12(S100A12)与病情和临床结局的关系。方法:选择2021年7月至2023年8月贵阳市第一人民医院收治的ANVUGIB患者184例作为研究组,同期体检健康者100例作为对照组。根据Rockall危险积分将患者分为低危组(28例)、中危组(60例)、高危组(96例),根据住院期间临床结局将患者分为预后不良组(66例)和预后良好组(118例)。检测RDW、血浆D-D、血清S100A12水平。采用多因素Logistic回归分析ANVUGIB患者临床结局不良的危险因素。结果:研究组RDW、血浆D-D、血清S100A12水平高于对照组(P<0.05)。高危组RDW、血浆D-D、血清S100A12水平显著高于中危组、低危组,中危组RDW、血浆D-D、血清S100A12水平显著高于低危组(P<0.05)。结局不良组患者RDW、血浆D-D、血清S100A12水平高于结局良好组(P<0.05)。多因素Logsitic回归分析显示,Rockall危险积分升高、出血量>1000 m L、RDW升高、血浆D-D升高、血清S100A12升高是ANVUGIB患者临床结局不良的危险因素(P<0.05)。结论:ANVUGIB患者RDW、D-D、S100A12水平与患者病情和临床结局密切相关,RDW升高、血浆D-D升高、血清S100A12升高是ANVUGIB患者临床结局不良的危险因素。
文摘目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12月期间在我院就诊的66例急性上消化道出血患者的临床资料,根据其入院时病情严重情况分为严重组(失血量≥750 mL,n=41)和非严重组(失血量<750 mL,n=25)。比较入院时两组患者血乳酸、RDW、PDW等指标水平,采用受试者工作特征(Receiver operating characteristic,ROC)曲线分析入院时血乳酸、RDW、PDW对急性上消化道出血患者的诊断效能。入院后30 d,根据快速序贯器官功能衰竭评估(Quick sequential organ failure assessment,qSOFA)评分将患者分为预后不良组(qSOFA≥1分)和预后良好组(qSOFA<1分)两亚组,比较两亚组患者入院后30 d血乳酸、RDW、PDW水平和qSOFA评分的关系。结果:入院时,严重组的血乳酸、RDW、PDW水平显著高于非严重组(P<0.05),血乳酸、RDW、PDW水平三者单一指标检测的ROC曲线下面积(Area under the ROC curve,AUC)值分别是0.861、0.769、0.763,差异具有统计学意义(P<0.05)。预后不良组入院时的血乳酸、RDW、PDW水平显著高于预后良好组(P<0.05),Pearson相关系数分析显示,血乳酸、RDW、PDW水平和qSOFA评分具有相关性。结论:血乳酸、RDW、PDW与急性上消化道出血患者预后密切相关,可以提供重要的诊断和治疗参考,帮助改善患者的预后和治疗效果。
文摘Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of children with asthma.Methods:Fifty-five children with suspected asthma were admitted to the hospital from July 2021 to July 2023.They underwent a bronchodilator test upon admission and their RDW,PDW,and IgE were detected.The efficacy of diagnosis with a single indicator(RDW/PDW/IgE)and combined parameters(PDW+PDW+IgE)were compared with the results of the bronchodilator test.Results:49 cases of pediatric asthma were diagnosed by the bronchodilator test.RDW and PDW of asthmatic children were lower than those of non-asthmatic children,while the IgE of asthmatic children was higher than that of non-asthmatic children,and there was a significant difference in the RDW,PDW,and IgE among children with different degrees of asthma severity(P<0.05).The positive rate of the three combined diagnostic tests of RDW,PDW,and IgE was significantly higher than the positive rate of a single-parameter diagnosis(P<0.05).Conclusion:The combination of RDW,PDW,and IgE plays a crucial role in the clinical diagnosis of asthmatic children.These tests further improve the efficiency of clinical diagnosis and help identify the severity of the disease.
文摘Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 60 elderly AECOPD patients were enrolled and divided into embolus group(12 cases)and thrombus group(48 cases)according to whether they were combined with pulmonary embolism and the MLPR,NLR,and RDW values of the two groups were determined respectively.Results:The patients in the two groups had different degrees of vascular structural and functional abnormalities,and the MLPR,NLR,and RDW in the embolus group were significantly higher than those in the thrombus group(P<0.05);while the differences in NLR and RDW between the two groups were not significant.Conclusion:MLPR,NLR,and RDW can provide an objective basis for assessing PE in elderly AECOPD patients.
