Rational Bezier surface is a widely used surface fitting tool in CAD. When all the weights of a rational B@zier surface go to infinity in the form of power function, the limit of surface is the regular control surface...Rational Bezier surface is a widely used surface fitting tool in CAD. When all the weights of a rational B@zier surface go to infinity in the form of power function, the limit of surface is the regular control surface induced by some lifting function, which is called toric degenerations of rational Bezier surfaces. In this paper, we study on the degenerations of the rational Bezier surface with weights in the exponential function and indicate the difference of our result and the work of Garcia-Puente et al. Through the transformation of weights in the form of exponential function and power function, the regular control surface of rational Bezier surface with weights in the exponential function is defined, which is just the limit of the surface. Compared with the power function, the exponential function approaches infinity faster, which leads to surface with the weights in the form of exponential function degenerates faster.展开更多
Background:Dietary Reference Intakes are used to guide the energy intake of the Canadian Armed Forces(CAF)field rations provided to military personnel deployed for training or operations.However,the high energy expend...Background:Dietary Reference Intakes are used to guide the energy intake of the Canadian Armed Forces(CAF)field rations provided to military personnel deployed for training or operations.However,the high energy expenditures likely to occur under harsh environmental/metabolically challenging deployment conditions may not be adequately considered.This study examined the Ad libitum energy and nutrient intakes of CAF personnel(n=18)consuming field rations in a resting thermoneutral environment and during a day of standardized strenuous infantry activities at varying environmental temperatures.Methods:Dietary intake was assessed using a measured food intake/food waste method during the experimental treatment and for 6 h after treatment.Four treatments were administered in a randomized counterbalanced design:exercise(as standardized infantry activities)in the heat(30℃),exercise in the cold(–10℃),exercise in temperate thermoneutral(21℃)air temperatures and a resting(sedentary)trial(21℃).Results:The average Ad libitum consumption of field rations was 70%of the provided total energy(2776±99 kcal/8 h)during all treatments.Even with an acute challenge of increased energy expenditure and temperature stress in the simulated field conditions,participants’energy intakes(1985±747 kcal/8 h)under hot,cold and temperate treatments did not differ from energy intake during the sedentary condition(1920±640 kcal/8 h).Participants’energy intakes(1009±527 kcal/6 h)did not increase during the 6 h posttreatment period when the stresses of the strenuous physical activities and the harsh environmental temperatures had subsided.Conclusions:These results should be considered when planning the provision of field rations for CAF personnel expected to be engaged in strenuous physical activities with prolonged exposure to temperature extremes.展开更多
The aim of the study was to determine the effect of supplementing an oat winter pasture with a total mixed ration (TMR) on lactation performance of dairy cows. Nine multiparous Holstein cows were used in a 3 × 3 ...The aim of the study was to determine the effect of supplementing an oat winter pasture with a total mixed ration (TMR) on lactation performance of dairy cows. Nine multiparous Holstein cows were used in a 3 × 3 Latin square design with three TMR: pasture ratios at 79:21 (T1), 58:42 (T2) and 33:67 (T3) on a dry matter (DM) basis. The response to the 100% TMR diet (TMR-100) was tested using an extra period of 14 days inmediately after finishing the Latin square schedule using the nine experimental cows. Total DM intake resulted higher in TMR-100 (28.2 (kg/cow·day) and decreased by 2.64 kg/cow·day in T1, 5.02 kg in T2 and 6.68 kg in T3. Yields of milk (31.2 kg/cow·day) and fat corrected milk (26.8 kg/cow·day) was similar between T1, T2 and T3. Milk yield resulted higher in TMR-100 (32.1 kg/cow·day) compared to T2 (30.7 kg/cow·day). Milk fat concentration (g/100 g) was higher in T2 (3.13) and T3 (3.20) compared to T1 (2.96) and TMR-100 (2.85) and milk fat yield did not differ. Milk protein content resulted higher in TMR-100 and T2 averaging 3.37 g/100 g compared to T1 (3.32 g/100 g). The lowest milk protein concentration was observed in T3 (3.29 g/100 g) that resulted only different to T2. Milk protein yield did not differ between T1, T2 and T3 averaging 1.03 kg/cow·day. A lower protein yield was detected in T2 (1.03) and T3 (1.00) when compared to TMR-100 (1.07). Efficiency of milk production (kg milk/kg DM intake) resulted higher in T3 (1.42) compared to T1 (1.25). Treatments that included pasture yielded a higher efficiency of milk production when compared to TMR-100 (1.13). Plasma urea concentration resulted lower in TMR-100 (33.8 mg/dl) with no significant differences for this parameter between the other treatments. Glucose plasma levels did not differ between T1, T2 and T3 but plasma non-esterified fatty acids (NEFA) gradually increased as the proportion of pasture was enhanced according to the lower energy intake. Plasma insulin levels were higher in TMR-100 and T2 whereas concentration of somatomedins (IGF-1) remained unaffected. Grouth hormone (GH) levels and the GH/insulin ratio were highly variable and not affected by treatments. Concentration of vaccenic and conjugated linoleic acids gradually increased with the inclusion of pasture in the diet. Supplementing a winter oat pasture with TMR may be a suitable strategy to maintain milk production with a high conversion efficiency but part of the produced milk could be sustained at the expense of endogenous energy mobilization. The conditions of replacing pasture for TMR in high yielding dairy cows should be defined taking into account the depressing effect of pasture on total DM and energy intake when fresh forage is included in high proportion in the diet.展开更多
Behavioral operations management(BOM)is one of the new areas in operations management.In the past 12 years,the field has made huge progress and researchers have become interested in this new perspective to solving ope...Behavioral operations management(BOM)is one of the new areas in operations management.In the past 12 years,the field has made huge progress and researchers have become interested in this new perspective to solving operational problems.BOM is now one of the major subfields of operations management.In this paper,we examine and categorize areas of BOM based on the mainstream literature.Key areas include behavioral issues in new product development and project management,quality management,production management,inventory management,service operations,and forecasting.Studies in each area are divided into three subcategories,including OM context,individual attributes,heuristics,and biases,and individual differences.In OM context category,feedback and reward,training,work monitoring,teamwork and group decision making,goal setting,task assignment,and flexibility are among the main topics.In individual attributes,heuristics,and biases category,sunk cost effect and escalation of commitment,endowment effect,overprecision bias,planning fallacy,pullto-center effect,anchoring and insufficient adjustment,and misperceptions of feedback are mainly discussed.In individual differences,analytic thinking and system thinking are mainly studied.New areas for research are suggested in each related section and are summarized in future directions and conclusion sections.In contexts such as new product development,project management,and inventory management,a shift to finding solution to performance improvement is beneficial instead of focusing on heuristics and biases and considering them as a deficiency in human decision making.Regarding individual differences category,a shift toward attributes other than cognitive abilities,such as global processing,creative thinking,and design thinking are recommended.展开更多
The aim of the current study was to investigate the effects of a lactic acid bacteria inoculant（Lactobacillus plantarum, LP）, fibrolytic enzyme（EN）, combination of LP and EN（LP＋EN） on fermentation quality, nutr...The aim of the current study was to investigate the effects of a lactic acid bacteria inoculant（Lactobacillus plantarum, LP）, fibrolytic enzyme（EN）, combination of LP and EN（LP＋EN） on fermentation quality, nutritive characteristics and in vitro digestibility of total mixed ration（TMR） silages containing 0, 7.5 and 15.0%（on dry matter basis） of rape（Brassica campestris L.） straw（RS）（denoted as CTMR, LTMR and MTMR, respectively）. After ensiling for 60 days, TMR silages without additives were well preserved, but MTMR had higher p H than CTMR and LTMR. There were no differences in other parameters of fermentation quality, microbial composition, nutrition and in vitro digestibility between CTMR and LTMR except for yeast and mold number and crude protein（CP） content. CTMR and LTMR silage had higher CP content, in vitro neutral detergent fiber digestibility（IVNDFD） and in vitro acid detergent fiber digestibility（IVADFD）, lower acid detergent fiber（ADF） content than MTMR silage. LP and EN decreased p H and increased dry matter（DM） recovery of TMR silages. LP＋EN improved the fermentation quality, nutritive characteristics and in vitro digestibility of TMR silages, showed by lower p H, ADF content, higher lactic acid content, in vitro dry matter digestibility（IVDMD） and IVNDFD. Therefore, It was suggested that TMR silage contained 7.5% RS on a DM basis and treated with LP＋EN can be as a useful feed for ruminant.展开更多
A test system was designed to study the parameters affecting the volumetric efficiency of a thick-material pump for coal slime.The parameters studied included solid concentration,the slenderness ratio of the suction c...A test system was designed to study the parameters affecting the volumetric efficiency of a thick-material pump for coal slime.The parameters studied included solid concentration,the slenderness ratio of the suction cylinder and the running speed of the hydraulic cylinder.In the experiment the concentrations of coal slime were 75.7%,76.3%,74.4%,73.5%,72.1%and 70.63%;the running speeds were 0.23,0.18,0.13,0.10 and 0.08 m/s;and the slenderness ratios of the suction cylinder were 1.63,2.26,2.88,3.50,4.13,4.78 and 5.38.The results show that the suction volumetric efficiency decreases gradually with an increase in material concentration.The critical concentration value is 72%;below 72%the suction volumetric efficiency is above 90%,otherwise it decreases rapidly.When the solid concentration reaches 76.3%,the suction volumetric efficiency is only 40%.When the running speed of the piston is less than or equal to 0.23 m/s,the suction volumetric efficiency increases with an increase in running speed.展开更多
Sea cucumber(Apostichopus japonicus)is an excellent model for investigating effects of bottom-dwellers on carbon mig-ration and transformation.However,the molecular mechanism of respiratory metabolism process variatio...Sea cucumber(Apostichopus japonicus)is an excellent model for investigating effects of bottom-dwellers on carbon mig-ration and transformation.However,the molecular mechanism of respiratory metabolism process variation caused by feeding rations is poorly understood.In this study,treatment groups set as 1%(about 0.63g),3%,and 7%of total body weight(named F1,F3 and F7 groups respectively).The potential molecular mechanisms behind the functions of respiratory tree and body wall were investigated by RNA-Seq.A total of 52411 expressed genes were identified from 89342 expressed transcripts.The results showed 759,254 and 334 genes were up-regulated,and 334,445 and 992 genes were down-regulated in respiratory tree of F1 vs.F3,F1 vs.F7 and F3 vs.F7,respectively.Meanwhile,2070,1601 and 896 genes were up-regulated,and 1303,1337 and 1144 genes were down-regulated in body wall between F1 vs.F3,F1 vs.F7 and F3 vs.F7,respectively.Differentially expressed genes were enriched in salivary secretion and ECM-receptor interaction pathways in respiratory tree,and in various types of N-glycan biosynthesis,ribosome and sphingolipid metabolism pathways in body wall.These results suggested respiratory tree and body wall were involved in activation of respiratory metabolisms in response to different feeding rations.Our research provided valuable knowledge for physiological differences in res-piratory metabolism.展开更多
This paper establishes a diagnostic model for assessing the rationality of size structure of urban agglomerations(UAs) in China. The model is designed to determine from a three-dimensional index including size distrib...This paper establishes a diagnostic model for assessing the rationality of size structure of urban agglomerations(UAs) in China. The model is designed to determine from a three-dimensional index including size distribution index(SDI), size compactness index(SCI), and size efficiency index(SEI). The spatio-temporal pattern of size structure involving the studied 19 UAs and its implications are explored. The results indicate that size structure of China's UAs advanced from a low rationality development stage to a moderate rationality development stage in 1995-2015.Among them, the SDI and SEI were reasonably high, and the SCI was relatively low. Spatially, the high rationality UAs were distributed across eastern China, while the low rationality UAs were located in western China. UAs with positive size structure possessed typically a dual-or multicenter urban structure, while UAs with negative size structure usually presented as a single-center structure. The evolutionary trajectories of rationality of size structure of UAs can be summarized as four different stages. Our findings suggest that, in addition to consolidating the status of national-level UAs, the development of regional-level UAs should be promoted. Also, the fostering focus and direction should be oriented toward an UA with dual-or multicenter spatial structure.展开更多
Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instru...Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instrumental rationality, normative appeal and practical appeal as well as global governance and state governance. Global and state governances are two strategic considerations in contemporary China. Actively participating in global governance and rationally promoting state governance is the rational choice of contemporary China, which plays a unique and significant role in realizing the social transformation and national rejuvenation and modernization of contemporary China. Deepening state governance with the help of global governance and promoting global governance with the support of state governance is the basic idea and dimension of understanding and grasping the interaction, coordination and overall planning between the two. The restrictions and effects of global governance on state governance are mainly reflected in such considerations as objects, mechanisms, concepts and interests of governance, and modernization of state governance system and improvement of governance capacity can promote and deepen global governance in a more effective way.展开更多
Dietary energy for chickens normally includes cereal grains and fat. This innovative study investigated the effect of replacing part of the corn and fat in broiler chicken rations with graded levels of sugar syrup on ...Dietary energy for chickens normally includes cereal grains and fat. This innovative study investigated the effect of replacing part of the corn and fat in broiler chicken rations with graded levels of sugar syrup on growth performance and biochemical parameters. Experimental treatments consisted of feeding a corn-soy basal diet alone, or with graded levels of sugar syrup in increments of 5%, 10% and 15%. All starter diets were isonitrogenous and isocaloric. Body weight gain and efficiency of feed utilization of chicks fed the control diet alone were not significantly(P < 0.05) different from chicks fed diets supplemented with either 5% or 15% sugar syrup. Supplementation of sugar syrup to broiler diets had no significant effect on blood glucose, creatinine, total protein, or liver enzymes. Adding 5% sugar syrup to broiler rations significantly decreased blood cholesterol and triglycerides in chickens fed the sugar syrup diet compared with birds fed the control diet. In conclusion, the results shows sugar syrup can be used in poultry ration to replace part of the corn as a source of energy. These results allowed the authors to recommend the safe usage of sugar syrup in broiler rations.展开更多
Viral diseases have contributed significantly to worldwide morbidity and mortality throughout history.Despite the existence of therapeutic treatments for many viral infections,antiviral resistance and the threat posed...Viral diseases have contributed significantly to worldwide morbidity and mortality throughout history.Despite the existence of therapeutic treatments for many viral infections,antiviral resistance and the threat posed by novel viruses highlight the need for an increased number of effective therapeutics.In addition to small molecule drugs and biologics,antimicrobial peptides(AMPs)represent an emerging class of potential antiviral therapeutics.While AMPs have traditionally been regarded in the context of their antibacterial activities,many AMPs are now known to be antiviral.These antiviral peptides(AVPs)have been shown to target and perturb viral membrane envelopes and inhibit various stages of the viral life cycle,from preattachment inhibition through viral release from infected host cells.Rational design of AMPs has also proven effective in identifying highly active and specific peptides and can aid in the discovery of lead peptides with high therapeutic selectivity.In this review,we highlight AVPs with strong antiviral activity largely curated from a publicly available AMP database.We then compile the sequences present in our AVP database to generate structural predictions of generic AVP motifs.Finally,we cover the rational design approaches available for AVPs taking into account approaches currently used for the rational design of AMPs.展开更多
This paper deals with two things. First, the cohomology of canonical extensions of real topological toric manifolds is computed when coefficient ring G is a commutative ring in which 2 is unit in G. Second, the author...This paper deals with two things. First, the cohomology of canonical extensions of real topological toric manifolds is computed when coefficient ring G is a commutative ring in which 2 is unit in G. Second, the author focuses on a specific canonical extensions called doublings and presents their various properties. They include existence of infinitely many real topological toric manifolds admitting complex structures, and a way to construct infinitely many real toric manifolds which have an odd torsion in their cohomology groups.Moreover, some questions about real topological toric manifolds related to Halperin's toral rank conjecture are presented.展开更多
Urban design is becoming a hot topic in academic discussions and engineering practice in the transformation of urban development in China. This paper systematically summarizes the historical development concerning urb...Urban design is becoming a hot topic in academic discussions and engineering practice in the transformation of urban development in China. This paper systematically summarizes the historical development concerning urban design ideas and thoughts. Based on an in-depth analysis on the development frontier in urban design discipline and professional field in both China and abroad, the paper concludes that urban design has undergone several development phases, including traditional urban design, modernist urban design, and green urban design. Considering the new urban design development trend that is characterized by digitalization as the method and tool, the paper puts forward the "digital urban design paradigm" as the fourth generation and sums up its five innovative values. The most important characteristic of urban design is "multi-scale experiential control on space in the whole chain," and digital urban design has greatly expanded the scale of such kind of experiential control. The relationships between the four generations of urban design paradigms are not simply successive, but inherited and partially iterative urban design "paradigm synthesis" under the joint effects of design objectives with difference in similarity, various spatial scales, and various social demands. Digital urban design possesses not only the social values and design originalities of man-machine dialogues, but also quantitative properties and database outcomes, which can more effectively combine with or even merge into the statutory urban planning system of China. Thereupon, the leap-forward development of urban design based on systematical coordination can be realized.展开更多
Background:Diet regulates rumen microbiota,which in turn affects animal health.The present study evaluated the response of rumen microbiota and the immune system of lambs to a fermented total mixed ration diet.Methods...Background:Diet regulates rumen microbiota,which in turn affects animal health.The present study evaluated the response of rumen microbiota and the immune system of lambs to a fermented total mixed ration diet.Methods:A total of 30 lambs were assigned into two groups:a group fed an unfermented high-fiber diet(total mixed ration[TMR])and a group fed an fermented low-fiber diet(fermented TMR[FTMR]).Results:The results showed that FTMR markedly(p<0.05)increased average daily gain and dry matter intake compared to TMR.The FTMR diet increased the relative abundance of Veillonellaceae_UCG-001 and decreased the diversity of undesirable microbiota despite stable overall microbial community diversity.Serum metabolomic analysis combined with enrichment analysis showed that serum metabolites were affected by the FTMR and metabolic pathways,and the FTMR diet significantly(p<0.05)influenced amino acid metabolism of lambs.There was a decrease in inflammatory factors in the FTMR treatment,indicating that inflammatory factors followed the same trajectory as changes in microbial community structure and function.Conclusions:Overall,the FTMR diet reduced undesirable microbiota diversity,thereby regulating host amino acid metabolism and improving immune status.展开更多
2.3 Examination and approval Unified planning,rational distribution and strict control are exercised by the state to the production and storage.of hazardous chemicals.The examination and approval sys-tem is also imple...2.3 Examination and approval Unified planning,rational distribution and strict control are exercised by the state to the production and storage.of hazardous chemicals.The examination and approval sys-tem is also implemented to the production and storage of hazardous chemicals.Enterprises,organizations and individuals are not allowed to make the production and stor-age of hazardous chemicals without examina-tion and approval.In formulating overall planning,local gov-展开更多
Let X be a closed simply connected rationally elliptic 4-manifold.The rational homotopy type of homotopy fixed point sets X^(hS^(1))is determined,and based on some relations between X^(hS^(1))and X^(S^(1)),the rationa...Let X be a closed simply connected rationally elliptic 4-manifold.The rational homotopy type of homotopy fixed point sets X^(hS^(1))is determined,and based on some relations between X^(hS^(1))and X^(S^(1)),the rational homotopy type of the fixed point set X^(S^(1))is determined.展开更多
This research aims to understand the causes of fraud through the approach of the Fraud Triangle Theory,which includes three main factors:pressure,opportunity,rationalization.By using the Systematic Literature Review m...This research aims to understand the causes of fraud through the approach of the Fraud Triangle Theory,which includes three main factors:pressure,opportunity,rationalization.By using the Systematic Literature Review method from various relevant international journals,it analyzed systematically to identify patterns,trends,and theoretical contributions to efforts in detecting and preventing fraud.The results of this study show that the three factors in the Fraud Triangle Theory significantly contribute to the occurrence of fraud.Opportunity as the most dominant factor is caused by weak internal control systems and lack of oversight.In addition,economic pressure,and a permissive organizational environment,as well as the rationalization processes by individuals,also increase the tendency for a person to commit fraud.These findings emphasize the need for a comprehensive approach in fraud prevention strategies,through ethical values,the establishment of an organizational culture with integrity,and the implementation of more effective internal control and oversight.展开更多
In the successive rise of the metaverse and artificial intelligence(AI),rationalism and emotionalism have consistently manifested as symptoms of modernity throughout their developmental trajectories.This paper argues ...In the successive rise of the metaverse and artificial intelligence(AI),rationalism and emotionalism have consistently manifested as symptoms of modernity throughout their developmental trajectories.This paper argues that the achievements and crises of both fields signify the triumph of rationalism in the context of deepening modernity,while simultaneously harboring an intrinsic impetus and possibility for transitioning from rationalism to emotionalism.This dynamic serves as a quintessential representation of modernity’s crises and their transcendence.Centered on embodied cognitive science,AI and the metaverse—rooted in rationalism—now face challenges in shifting toward emotionalism,revealing their inadequacy in addressing this shift.Humanity must explore new modernity-deepening paradigms grounded in emotionalism to confront and transcend the potential crises posed by the metaverse and AI.展开更多
基金Supported by the National Natural Science Foundation of China(11671068,11271060,11601064,11290143)Fundamental Research of Civil Aircraft(MJ-F-2012-04)the Fundamental Research Funds for the Central Universities(DUT16LK38)
文摘Rational Bezier surface is a widely used surface fitting tool in CAD. When all the weights of a rational B@zier surface go to infinity in the form of power function, the limit of surface is the regular control surface induced by some lifting function, which is called toric degenerations of rational Bezier surfaces. In this paper, we study on the degenerations of the rational Bezier surface with weights in the exponential function and indicate the difference of our result and the work of Garcia-Puente et al. Through the transformation of weights in the form of exponential function and power function, the regular control surface of rational Bezier surface with weights in the exponential function is defined, which is just the limit of the surface. Compared with the power function, the exponential function approaches infinity faster, which leads to surface with the weights in the form of exponential function degenerates faster.
基金funded in part by Defence Research&Development Canada(DRDC)approved by the Canadian Forces Surgeon General’s Health Research Programthe Department of National Defence(DND)policy。
文摘Background:Dietary Reference Intakes are used to guide the energy intake of the Canadian Armed Forces(CAF)field rations provided to military personnel deployed for training or operations.However,the high energy expenditures likely to occur under harsh environmental/metabolically challenging deployment conditions may not be adequately considered.This study examined the Ad libitum energy and nutrient intakes of CAF personnel(n=18)consuming field rations in a resting thermoneutral environment and during a day of standardized strenuous infantry activities at varying environmental temperatures.Methods:Dietary intake was assessed using a measured food intake/food waste method during the experimental treatment and for 6 h after treatment.Four treatments were administered in a randomized counterbalanced design:exercise(as standardized infantry activities)in the heat(30℃),exercise in the cold(–10℃),exercise in temperate thermoneutral(21℃)air temperatures and a resting(sedentary)trial(21℃).Results:The average Ad libitum consumption of field rations was 70%of the provided total energy(2776±99 kcal/8 h)during all treatments.Even with an acute challenge of increased energy expenditure and temperature stress in the simulated field conditions,participants’energy intakes(1985±747 kcal/8 h)under hot,cold and temperate treatments did not differ from energy intake during the sedentary condition(1920±640 kcal/8 h).Participants’energy intakes(1009±527 kcal/6 h)did not increase during the 6 h posttreatment period when the stresses of the strenuous physical activities and the harsh environmental temperatures had subsided.Conclusions:These results should be considered when planning the provision of field rations for CAF personnel expected to be engaged in strenuous physical activities with prolonged exposure to temperature extremes.
文摘The aim of the study was to determine the effect of supplementing an oat winter pasture with a total mixed ration (TMR) on lactation performance of dairy cows. Nine multiparous Holstein cows were used in a 3 × 3 Latin square design with three TMR: pasture ratios at 79:21 (T1), 58:42 (T2) and 33:67 (T3) on a dry matter (DM) basis. The response to the 100% TMR diet (TMR-100) was tested using an extra period of 14 days inmediately after finishing the Latin square schedule using the nine experimental cows. Total DM intake resulted higher in TMR-100 (28.2 (kg/cow·day) and decreased by 2.64 kg/cow·day in T1, 5.02 kg in T2 and 6.68 kg in T3. Yields of milk (31.2 kg/cow·day) and fat corrected milk (26.8 kg/cow·day) was similar between T1, T2 and T3. Milk yield resulted higher in TMR-100 (32.1 kg/cow·day) compared to T2 (30.7 kg/cow·day). Milk fat concentration (g/100 g) was higher in T2 (3.13) and T3 (3.20) compared to T1 (2.96) and TMR-100 (2.85) and milk fat yield did not differ. Milk protein content resulted higher in TMR-100 and T2 averaging 3.37 g/100 g compared to T1 (3.32 g/100 g). The lowest milk protein concentration was observed in T3 (3.29 g/100 g) that resulted only different to T2. Milk protein yield did not differ between T1, T2 and T3 averaging 1.03 kg/cow·day. A lower protein yield was detected in T2 (1.03) and T3 (1.00) when compared to TMR-100 (1.07). Efficiency of milk production (kg milk/kg DM intake) resulted higher in T3 (1.42) compared to T1 (1.25). Treatments that included pasture yielded a higher efficiency of milk production when compared to TMR-100 (1.13). Plasma urea concentration resulted lower in TMR-100 (33.8 mg/dl) with no significant differences for this parameter between the other treatments. Glucose plasma levels did not differ between T1, T2 and T3 but plasma non-esterified fatty acids (NEFA) gradually increased as the proportion of pasture was enhanced according to the lower energy intake. Plasma insulin levels were higher in TMR-100 and T2 whereas concentration of somatomedins (IGF-1) remained unaffected. Grouth hormone (GH) levels and the GH/insulin ratio were highly variable and not affected by treatments. Concentration of vaccenic and conjugated linoleic acids gradually increased with the inclusion of pasture in the diet. Supplementing a winter oat pasture with TMR may be a suitable strategy to maintain milk production with a high conversion efficiency but part of the produced milk could be sustained at the expense of endogenous energy mobilization. The conditions of replacing pasture for TMR in high yielding dairy cows should be defined taking into account the depressing effect of pasture on total DM and energy intake when fresh forage is included in high proportion in the diet.
文摘Behavioral operations management(BOM)is one of the new areas in operations management.In the past 12 years,the field has made huge progress and researchers have become interested in this new perspective to solving operational problems.BOM is now one of the major subfields of operations management.In this paper,we examine and categorize areas of BOM based on the mainstream literature.Key areas include behavioral issues in new product development and project management,quality management,production management,inventory management,service operations,and forecasting.Studies in each area are divided into three subcategories,including OM context,individual attributes,heuristics,and biases,and individual differences.In OM context category,feedback and reward,training,work monitoring,teamwork and group decision making,goal setting,task assignment,and flexibility are among the main topics.In individual attributes,heuristics,and biases category,sunk cost effect and escalation of commitment,endowment effect,overprecision bias,planning fallacy,pullto-center effect,anchoring and insufficient adjustment,and misperceptions of feedback are mainly discussed.In individual differences,analytic thinking and system thinking are mainly studied.New areas for research are suggested in each related section and are summarized in future directions and conclusion sections.In contexts such as new product development,project management,and inventory management,a shift to finding solution to performance improvement is beneficial instead of focusing on heuristics and biases and considering them as a deficiency in human decision making.Regarding individual differences category,a shift toward attributes other than cognitive abilities,such as global processing,creative thinking,and design thinking are recommended.
基金supported by the Natural Science Foundation of the Jiangsu Province for Young Scholars,China(BK20130694)the Specialized Research Fund for the Doctoral Program of Higher Education,China(20130097120053)+1 种基金the National Natural Science Foundation of China(31502014)the Project of Jiangsu Independent Innovation,China(CX(15)1003)
文摘The aim of the current study was to investigate the effects of a lactic acid bacteria inoculant（Lactobacillus plantarum, LP）, fibrolytic enzyme（EN）, combination of LP and EN（LP＋EN） on fermentation quality, nutritive characteristics and in vitro digestibility of total mixed ration（TMR） silages containing 0, 7.5 and 15.0%（on dry matter basis） of rape（Brassica campestris L.） straw（RS）（denoted as CTMR, LTMR and MTMR, respectively）. After ensiling for 60 days, TMR silages without additives were well preserved, but MTMR had higher p H than CTMR and LTMR. There were no differences in other parameters of fermentation quality, microbial composition, nutrition and in vitro digestibility between CTMR and LTMR except for yeast and mold number and crude protein（CP） content. CTMR and LTMR silage had higher CP content, in vitro neutral detergent fiber digestibility（IVNDFD） and in vitro acid detergent fiber digestibility（IVADFD）, lower acid detergent fiber（ADF） content than MTMR silage. LP and EN decreased p H and increased dry matter（DM） recovery of TMR silages. LP＋EN improved the fermentation quality, nutritive characteristics and in vitro digestibility of TMR silages, showed by lower p H, ADF content, higher lactic acid content, in vitro dry matter digestibility（IVDMD） and IVNDFD. Therefore, It was suggested that TMR silage contained 7.5% RS on a DM basis and treated with LP＋EN can be as a useful feed for ruminant.
基金Projects 02C26211100499 supported by Science and Technology Corporation Innovation Fund of China 20020290011 by the Ph.D Program Fund
文摘A test system was designed to study the parameters affecting the volumetric efficiency of a thick-material pump for coal slime.The parameters studied included solid concentration,the slenderness ratio of the suction cylinder and the running speed of the hydraulic cylinder.In the experiment the concentrations of coal slime were 75.7%,76.3%,74.4%,73.5%,72.1%and 70.63%;the running speeds were 0.23,0.18,0.13,0.10 and 0.08 m/s;and the slenderness ratios of the suction cylinder were 1.63,2.26,2.88,3.50,4.13,4.78 and 5.38.The results show that the suction volumetric efficiency decreases gradually with an increase in material concentration.The critical concentration value is 72%;below 72%the suction volumetric efficiency is above 90%,otherwise it decreases rapidly.When the solid concentration reaches 76.3%,the suction volumetric efficiency is only 40%.When the running speed of the piston is less than or equal to 0.23 m/s,the suction volumetric efficiency increases with an increase in running speed.
基金supported by the National Natural Science Foundation of China(No.31672657).
文摘Sea cucumber(Apostichopus japonicus)is an excellent model for investigating effects of bottom-dwellers on carbon mig-ration and transformation.However,the molecular mechanism of respiratory metabolism process variation caused by feeding rations is poorly understood.In this study,treatment groups set as 1%(about 0.63g),3%,and 7%of total body weight(named F1,F3 and F7 groups respectively).The potential molecular mechanisms behind the functions of respiratory tree and body wall were investigated by RNA-Seq.A total of 52411 expressed genes were identified from 89342 expressed transcripts.The results showed 759,254 and 334 genes were up-regulated,and 334,445 and 992 genes were down-regulated in respiratory tree of F1 vs.F3,F1 vs.F7 and F3 vs.F7,respectively.Meanwhile,2070,1601 and 896 genes were up-regulated,and 1303,1337 and 1144 genes were down-regulated in body wall between F1 vs.F3,F1 vs.F7 and F3 vs.F7,respectively.Differentially expressed genes were enriched in salivary secretion and ECM-receptor interaction pathways in respiratory tree,and in various types of N-glycan biosynthesis,ribosome and sphingolipid metabolism pathways in body wall.These results suggested respiratory tree and body wall were involved in activation of respiratory metabolisms in response to different feeding rations.Our research provided valuable knowledge for physiological differences in res-piratory metabolism.
基金supported by the National Social Science Foundation of China [Grant number:17CJY015]the Stragegic Priority Research Program of the Chinese Academy of Sciences [Grant number:XDA19040501]+1 种基金the Fundamental Research Funds for the Central Universities[Grant number:2018RW01]Beijing Natural Science Foundation [Grant number:9184035]
文摘This paper establishes a diagnostic model for assessing the rationality of size structure of urban agglomerations(UAs) in China. The model is designed to determine from a three-dimensional index including size distribution index(SDI), size compactness index(SCI), and size efficiency index(SEI). The spatio-temporal pattern of size structure involving the studied 19 UAs and its implications are explored. The results indicate that size structure of China's UAs advanced from a low rationality development stage to a moderate rationality development stage in 1995-2015.Among them, the SDI and SEI were reasonably high, and the SCI was relatively low. Spatially, the high rationality UAs were distributed across eastern China, while the low rationality UAs were located in western China. UAs with positive size structure possessed typically a dual-or multicenter urban structure, while UAs with negative size structure usually presented as a single-center structure. The evolutionary trajectories of rationality of size structure of UAs can be summarized as four different stages. Our findings suggest that, in addition to consolidating the status of national-level UAs, the development of regional-level UAs should be promoted. Also, the fostering focus and direction should be oriented toward an UA with dual-or multicenter spatial structure.
文摘Governance is a kind of holistic governance and the notion of governing holistically should be established. The holisticity of governance is reflected in the unity and coordination between value rationality and instrumental rationality, normative appeal and practical appeal as well as global governance and state governance. Global and state governances are two strategic considerations in contemporary China. Actively participating in global governance and rationally promoting state governance is the rational choice of contemporary China, which plays a unique and significant role in realizing the social transformation and national rejuvenation and modernization of contemporary China. Deepening state governance with the help of global governance and promoting global governance with the support of state governance is the basic idea and dimension of understanding and grasping the interaction, coordination and overall planning between the two. The restrictions and effects of global governance on state governance are mainly reflected in such considerations as objects, mechanisms, concepts and interests of governance, and modernization of state governance system and improvement of governance capacity can promote and deepen global governance in a more effective way.
文摘Dietary energy for chickens normally includes cereal grains and fat. This innovative study investigated the effect of replacing part of the corn and fat in broiler chicken rations with graded levels of sugar syrup on growth performance and biochemical parameters. Experimental treatments consisted of feeding a corn-soy basal diet alone, or with graded levels of sugar syrup in increments of 5%, 10% and 15%. All starter diets were isonitrogenous and isocaloric. Body weight gain and efficiency of feed utilization of chicks fed the control diet alone were not significantly(P < 0.05) different from chicks fed diets supplemented with either 5% or 15% sugar syrup. Supplementation of sugar syrup to broiler diets had no significant effect on blood glucose, creatinine, total protein, or liver enzymes. Adding 5% sugar syrup to broiler rations significantly decreased blood cholesterol and triglycerides in chickens fed the sugar syrup diet compared with birds fed the control diet. In conclusion, the results shows sugar syrup can be used in poultry ration to replace part of the corn as a source of energy. These results allowed the authors to recommend the safe usage of sugar syrup in broiler rations.
基金the NIGMS of the National Institutes of Health under grant number T32GM007388.
文摘Viral diseases have contributed significantly to worldwide morbidity and mortality throughout history.Despite the existence of therapeutic treatments for many viral infections,antiviral resistance and the threat posed by novel viruses highlight the need for an increased number of effective therapeutics.In addition to small molecule drugs and biologics,antimicrobial peptides(AMPs)represent an emerging class of potential antiviral therapeutics.While AMPs have traditionally been regarded in the context of their antibacterial activities,many AMPs are now known to be antiviral.These antiviral peptides(AVPs)have been shown to target and perturb viral membrane envelopes and inhibit various stages of the viral life cycle,from preattachment inhibition through viral release from infected host cells.Rational design of AMPs has also proven effective in identifying highly active and specific peptides and can aid in the discovery of lead peptides with high therapeutic selectivity.In this review,we highlight AVPs with strong antiviral activity largely curated from a publicly available AMP database.We then compile the sequences present in our AVP database to generate structural predictions of generic AVP motifs.Finally,we cover the rational design approaches available for AVPs taking into account approaches currently used for the rational design of AMPs.
文摘This paper deals with two things. First, the cohomology of canonical extensions of real topological toric manifolds is computed when coefficient ring G is a commutative ring in which 2 is unit in G. Second, the author focuses on a specific canonical extensions called doublings and presents their various properties. They include existence of infinitely many real topological toric manifolds admitting complex structures, and a way to construct infinitely many real toric manifolds which have an odd torsion in their cohomology groups.Moreover, some questions about real topological toric manifolds related to Halperin's toral rank conjecture are presented.
文摘Urban design is becoming a hot topic in academic discussions and engineering practice in the transformation of urban development in China. This paper systematically summarizes the historical development concerning urban design ideas and thoughts. Based on an in-depth analysis on the development frontier in urban design discipline and professional field in both China and abroad, the paper concludes that urban design has undergone several development phases, including traditional urban design, modernist urban design, and green urban design. Considering the new urban design development trend that is characterized by digitalization as the method and tool, the paper puts forward the "digital urban design paradigm" as the fourth generation and sums up its five innovative values. The most important characteristic of urban design is "multi-scale experiential control on space in the whole chain," and digital urban design has greatly expanded the scale of such kind of experiential control. The relationships between the four generations of urban design paradigms are not simply successive, but inherited and partially iterative urban design "paradigm synthesis" under the joint effects of design objectives with difference in similarity, various spatial scales, and various social demands. Digital urban design possesses not only the social values and design originalities of man-machine dialogues, but also quantitative properties and database outcomes, which can more effectively combine with or even merge into the statutory urban planning system of China. Thereupon, the leap-forward development of urban design based on systematical coordination can be realized.
基金Key Technology Integration and Demonstration of Advantageous and Characteristic Industries in the Typical Farming-Pastoral Ecotone of Inner Mongolia,Grant/Award Number:2022YFD1601203。
文摘Background:Diet regulates rumen microbiota,which in turn affects animal health.The present study evaluated the response of rumen microbiota and the immune system of lambs to a fermented total mixed ration diet.Methods:A total of 30 lambs were assigned into two groups:a group fed an unfermented high-fiber diet(total mixed ration[TMR])and a group fed an fermented low-fiber diet(fermented TMR[FTMR]).Results:The results showed that FTMR markedly(p<0.05)increased average daily gain and dry matter intake compared to TMR.The FTMR diet increased the relative abundance of Veillonellaceae_UCG-001 and decreased the diversity of undesirable microbiota despite stable overall microbial community diversity.Serum metabolomic analysis combined with enrichment analysis showed that serum metabolites were affected by the FTMR and metabolic pathways,and the FTMR diet significantly(p<0.05)influenced amino acid metabolism of lambs.There was a decrease in inflammatory factors in the FTMR treatment,indicating that inflammatory factors followed the same trajectory as changes in microbial community structure and function.Conclusions:Overall,the FTMR diet reduced undesirable microbiota diversity,thereby regulating host amino acid metabolism and improving immune status.
文摘2.3 Examination and approval Unified planning,rational distribution and strict control are exercised by the state to the production and storage.of hazardous chemicals.The examination and approval sys-tem is also implemented to the production and storage of hazardous chemicals.Enterprises,organizations and individuals are not allowed to make the production and stor-age of hazardous chemicals without examina-tion and approval.In formulating overall planning,local gov-
文摘Let X be a closed simply connected rationally elliptic 4-manifold.The rational homotopy type of homotopy fixed point sets X^(hS^(1))is determined,and based on some relations between X^(hS^(1))and X^(S^(1)),the rational homotopy type of the fixed point set X^(S^(1))is determined.
文摘This research aims to understand the causes of fraud through the approach of the Fraud Triangle Theory,which includes three main factors:pressure,opportunity,rationalization.By using the Systematic Literature Review method from various relevant international journals,it analyzed systematically to identify patterns,trends,and theoretical contributions to efforts in detecting and preventing fraud.The results of this study show that the three factors in the Fraud Triangle Theory significantly contribute to the occurrence of fraud.Opportunity as the most dominant factor is caused by weak internal control systems and lack of oversight.In addition,economic pressure,and a permissive organizational environment,as well as the rationalization processes by individuals,also increase the tendency for a person to commit fraud.These findings emphasize the need for a comprehensive approach in fraud prevention strategies,through ethical values,the establishment of an organizational culture with integrity,and the implementation of more effective internal control and oversight.
基金supported by the China Metaverse and Digital Talent Development Initiative and the general project of the National Social Science Foundation of China titled“Theoretical Interpretation of Advertising Messaging and the Development of a Typical Case Database”(19BXW085).
文摘In the successive rise of the metaverse and artificial intelligence(AI),rationalism and emotionalism have consistently manifested as symptoms of modernity throughout their developmental trajectories.This paper argues that the achievements and crises of both fields signify the triumph of rationalism in the context of deepening modernity,while simultaneously harboring an intrinsic impetus and possibility for transitioning from rationalism to emotionalism.This dynamic serves as a quintessential representation of modernity’s crises and their transcendence.Centered on embodied cognitive science,AI and the metaverse—rooted in rationalism—now face challenges in shifting toward emotionalism,revealing their inadequacy in addressing this shift.Humanity must explore new modernity-deepening paradigms grounded in emotionalism to confront and transcend the potential crises posed by the metaverse and AI.
