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Dynamic modeling and simulation of irregular faults in axle box bearings of high-speed trains
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作者 Xiaohui GU Yajia WANG +2 位作者 Pengfei LIU Zechao LIU Shaopu YANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第10期1883-1902,共20页
Axle box bearings are critical components of high-speed trains.Localized defects,such as pitting and spalling,on raceways or rollers pose significant threats to the operational safety of railway vehicles.In this work,... Axle box bearings are critical components of high-speed trains.Localized defects,such as pitting and spalling,on raceways or rollers pose significant threats to the operational safety of railway vehicles.In this work,a novel bearing-flexible axle boxvehicle coupling model is established to explore the vibration characteristics of axle box bearings with irregular localized defects.First,based on the contact and kinematic relationship between rollers and raceways,the three-dimensional(3D)bearing force elements are analyzed and formulated.Second,the established model and a flexible axle box are integrated into the vehicle,and the responses of the normal and faulty bearings under the combined excitations of wheel roughness and track irregularities are simulated.Third,the simulation results are verified through a rolling-vibrating test bench for full-scale wheelsets of high-speed trains.The comparisons of the fault-induced repetitive transients in the time-domain and the fault characteristic frequencies in the envelope spectra demonstrate the efficiency of the proposed model.Finally,based on the flexible axle box model,a sensitivity analysis of the accelerometer placements to the bearing faults is carried out,and the optimal one is identified based on both the time-domain and frequency-domain signal-to-noise ratios(SNRs)for engineering applications. 展开更多
关键词 axle box bearing irregular fault track irregularity flexible axle box accelerometer placement selection
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A clip-on composite sensor based packaging design method for fiber Bragg grating axle counter
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作者 Mengyao Zhao Xueyun Cao +2 位作者 Longsheng Wang Yang Peng Tao Wang 《Railway Sciences》 2025年第5期647-665,共19页
Purpose–To address the encapsulation challenge of fiber Bragg grating(FBG)sensors in complex railway environments,this paper designs a clip-on composite sensor enabling installation-friendly deployment and long-term ... Purpose–To address the encapsulation challenge of fiber Bragg grating(FBG)sensors in complex railway environments,this paper designs a clip-on composite sensor enabling installation-friendly deployment and long-term axle counting system monitoring.Design/methodology/approach–Wheel–rail mechanical behavior was simulated via finite element analysis(FEA)to determine optimal sensor placement.A clip-on composite sensor was subsequently engineered.Stress transduction efficacy was validated through FEA quantification of stress responses at the axle counter location.Findings–The proposed FBG axle counter integrates temperature compensation and anti-detachment monitoring as well as advantages such as simplified installation with minimal maintenance and sustained operational reliability.It effectively transmits stress,yielding a measured strain of 39μe under static loading conditions without sensitivity-enhancing elements.Originality/value–This study performs FEA of wheel-rail stress distribution and engineers the dual-slot composite sensor,FEAwas conducted to quantify the stress magnitude at the axle sensor position of the dual-slot composite sensor.Additionally,FEA was performed on sensors with different structural configurations,including adjustments to the axle sensor position,number of slots and axle position.The results confirmed that the designed composite sensor exhibits superior stress transfer characteristics. 展开更多
关键词 Fiber Bragg grating axle counting Finite element Sensor Wheel-rail forces
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Lightweight Design of Front Axle Structure of a Certain Type of Automobile
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作者 Chuan qi LI Jian ZOU +2 位作者 Bing Ll Yiming LEI Mingshuo ZHANG 《Mechanical Engineering Science》 2025年第1期26-32,共7页
In this paper,the front axle of a certain model is taken as the research object,and the stress and deformation of the frontaxle under three typical working conditions are analyzed by finite element technology.Based on... In this paper,the front axle of a certain model is taken as the research object,and the stress and deformation of the frontaxle under three typical working conditions are analyzed by finite element technology.Based on the simulation results,the 3D model of the front axle was optimized,and the finite element analysis of the optimized structure of the front axle under three typical working conditions was carried out to verify the correctness of the model.Finally,the fatigue tool module of ANSYS Workbench was used to analyze the fatigue life of the front axle under the optimized emergency conditions,and the feasibility of the model was verified.The analysis data shows that the design of the front axle components still has a lot of potential for lightweighting,and the weight of the front axle can be reduced by 6.73%through optimization,and the performance of the front axle can also meet the needs of use.The research conclusionhas a certain reference value for the lightweight design of automobile front axle. 展开更多
关键词 automobile front axle structural optimization Fatigue life
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Damage Tolerance Assessment of Heavy-Duty Freight Railway Axles with Artificial Defects
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作者 Hai Zhao Ding Liao +4 位作者 Jiewei Gao Shunpeng Zhu Ligen Liu Jing Han Shantong Li 《Chinese Journal of Mechanical Engineering》 2025年第2期394-406,共13页
Heavy-duty freight railway axles are no less important than those of passenger trains,owing to the potentially catastrophic results caused by the derailment of trains carrying hazardous substances.Intrinsic and extrin... Heavy-duty freight railway axles are no less important than those of passenger trains,owing to the potentially catastrophic results caused by the derailment of trains carrying hazardous substances.Intrinsic and extrinsic imperfections challenge classical design theories built based on the safe life concept,and damage tolerance assessment becomes vital for the safety and reliability of long-term serviced railway axles,as pits and scratches are common defects for heavy-duty railway axles.In this work,four-point rotating bending fatigue tests of AAR-CM railway axle steel specimens with semicircular and circumferential groove notches are conducted.The fatigue limit of the semicircular notched specimens was evaluated based on fracture mechanics theory,in which non-conservative results are obtained by the El Haddad model and the S–N curves of circumferential groove notched specimens are correlated by the theory of critical distance(TCD). 展开更多
关键词 Heavy-duty railway axle Damage tolerance NOTCH K-T diagram Theory of critical distance
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当归芍药散调控EPO/PPAR-γ/AXL通路增强小胶质细胞吞噬改善血管性认知障碍
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作者 李翔 袁宁宁 +2 位作者 徐莹 苏越 成小兰 《中国中西医结合杂志》 北大核心 2025年第6期706-713,共8页
目的 观察当归芍药散(DSS)对血管性认知障碍(VCI)大鼠认知功能和促红细胞生成素(EPO)/过氧化物酶体增殖物激活受体γ(PPAR-γ)/AXL受体酪氨酸激酶(AXL)/AXL通路的影响,探讨其作用机制。方法 将40只SD大鼠随机分为假手术组(Sham组)、模型... 目的 观察当归芍药散(DSS)对血管性认知障碍(VCI)大鼠认知功能和促红细胞生成素(EPO)/过氧化物酶体增殖物激活受体γ(PPAR-γ)/AXL受体酪氨酸激酶(AXL)/AXL通路的影响,探讨其作用机制。方法 将40只SD大鼠随机分为假手术组(Sham组)、模型组(VCI组)、模型+当归芍药散低剂量组(5 g/kg)、模型+当归芍药散高剂量组(10 g/kg)及模型+尼莫地平组(Nimodipine,NMP组,9.45 mg/kg),每组8只。除Sham组外,其余各组采用双侧颈总动永久性脉结扎法建立VCI模型,造模后立即给药干预,Sham组和模型组灌胃等量生理盐水,给药4周。采用Morris水迷宫测试大鼠学习记忆能力,HE染色检测大鼠海马组织损伤,牢固蓝染色(LFB)检测大鼠海马髓鞘损伤,免疫荧光染色检测大鼠小胶质细胞活化状态和髓鞘相关蛋白,荧光定量PCR检测小胶质细胞M2极化标志物和吞噬相关基因mRNA表达水平,ELISA检测炎症因子表达,Western Blot检测EPO通路相关蛋白表达。结果 与模型组比较,DSS高剂量组穿越平台次数增加,目标象限停留时间延长,逃逸潜伏期缩短(P<0.01)。ELISA检测结果显示,DSS高剂量组大鼠海马中炎症相关因子IL-6、TNF-α、单核细胞趋化蛋白1(MCP-1)降低(P<0.05)。荧光定量PCR结果显示,DSS高剂量组小胶质细胞M1极化标志物CD68表达下降,而M2极化标志物CD206、精氨酸酶1(Arg-1)表达升高(P<0.01,P<0.05)。Western Blot结果表明,DSS组EPO、PPAR-γ和AXL蛋白表达上调(P<0.01)。结论 DSS高剂量通过调控EPO/PPAR-γ/AXL通路增强海马小胶质细胞吞噬功能,并向M2型极化减轻神经炎症,进而改善VCI。 展开更多
关键词 血管性认知障碍 当归芍药散 小胶质细胞 促红细胞生成素 过氧化物酶体增殖物激活受体Γ axl受体酪氨酸激酶 中药复方 中西医结合
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益母草碱调节GAS6/Axl信号通路对冠心病大鼠心肌损伤的影响 被引量:1
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作者 孟王桃 崔冬玲 +2 位作者 吴冬景 陈超 张颖颖 《中国药房》 北大核心 2025年第1期51-56,共6页
目的探讨益母草碱对生长停滞特异性蛋白6(GAS6)/酪氨酸蛋白激酶受体(Axl)信号通路的影响,阐明其减轻冠心病大鼠心肌损伤的机制。方法构建冠心病大鼠模型,将造模成功的大鼠按随机抽样方法分为模型组,益母草碱低、高剂量组(分别灌胃25、10... 目的探讨益母草碱对生长停滞特异性蛋白6(GAS6)/酪氨酸蛋白激酶受体(Axl)信号通路的影响,阐明其减轻冠心病大鼠心肌损伤的机制。方法构建冠心病大鼠模型,将造模成功的大鼠按随机抽样方法分为模型组,益母草碱低、高剂量组(分别灌胃25、100 mg/kg益母草碱+腹腔注射75 mg/kg生理盐水),益母草碱高剂量+GAS6/Axl信号通路抑制剂组(灌胃100 mg/kg益母草碱+腹腔注射75 mg/kg的R428),每组12只;另取12只正常大鼠作对照组。各给药组大鼠给予相应药物,对照组和模型组大鼠灌胃并腹腔注射等体积生理盐水,每天1次,连续48 d。给药结束后,检测大鼠心功能和血清中炎症因子及心肌损伤标志物水平;观察其心肌组织病理形态;检测其心肌组织细胞凋亡率和心肌组织中凋亡及GAS6/Axl信号通路相关蛋白表达。结果与对照组比较,模型组大鼠出现心肌细胞与心肌纤维排列紊乱、心肌细胞肥大、细胞核固缩等病变,左室射血分数、左室短轴缩短率、二尖瓣环舒张早期与舒张晚期运动速度之比及GAS6蛋白相对表达量和B细胞淋巴瘤2/B细胞淋巴瘤2相关X蛋白、磷酸化Axl/Axl比值均显著降低(P<0.05),肿瘤坏死因子α、白细胞介素1β、白细胞介素6、肌酸激酶同工酶、肌钙蛋白Ⅰ、肌红蛋白水平以及心肌组织细胞凋亡率和剪切型胱天蛋白酶3/胱天蛋白酶3比值均显著升高(P<0.05);益母草碱各剂量组大鼠上述病理情况及各检测指标均显著改善(P<0.05),且益母草碱高剂量组效果较益母草碱低剂量组明显(P<0.05);R428处理可逆转高剂量益母草碱对冠心病大鼠心肌损伤的改善作用(P<0.05)。结论益母草碱可减轻冠心病大鼠心肌损伤,其作用机制可能与激活GAS6/Axl信号通路相关。 展开更多
关键词 益母草碱 GAS6/axl信号通路 冠心病 心肌损伤
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当归六黄汤通过激活Tyro3/Axl受体活性治疗桥本甲状腺炎大鼠的实验研究 被引量:1
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作者 吴静泽 王晔恺 +1 位作者 陈位 金丹雯 《浙江中西医结合杂志》 2025年第3期200-204,共5页
目的探讨当归六黄汤治疗桥本甲状腺炎大鼠的可能作用机制。方法24只雄性大鼠适应性喂养1周后,按随机数字表法分为空白组、模型组、安慰剂组及当归六黄汤组,每组6只。空白组不予任何处理直接处死。模型组、安慰剂组和当归六黄汤组大鼠通... 目的探讨当归六黄汤治疗桥本甲状腺炎大鼠的可能作用机制。方法24只雄性大鼠适应性喂养1周后,按随机数字表法分为空白组、模型组、安慰剂组及当归六黄汤组,每组6只。空白组不予任何处理直接处死。模型组、安慰剂组和当归六黄汤组大鼠通过在尾根和足垫皮下注射甲状腺球蛋白各100μg,每周1次,持续7周,建立桥本甲状腺炎模型。从第8周开始,安慰剂组和当归六黄汤组分别予安慰剂(40 g/L)和当归六黄汤水煎液(144 g/L)灌胃,每次2 mL,每天1次。第11周处死模型组、安慰剂组和中药组所有大鼠,采集血液和甲状腺组织。CT检测大鼠甲状腺组织肿胀情况,流式细胞术检测外周血CD3^(+)T细胞表面Tyro3、Axl的平均荧光强度(MFI),酶联免疫吸附试验(ELISA)检测血清抗甲状腺球蛋白抗体(TG-Ab)和抗甲状腺过氧化物酶抗体(TPO-Ab)水平,免疫组化检测甲状腺组织Tyro3和Axl表达,实时荧光定量PCR检测甲状腺组织Tyro3、Axl、B细胞淋巴瘤-2(Bcl-2)、Bcl-2相关X蛋白(Bax)mRNA表达。结果与模型组和安慰剂组比较,中药组CT下可见甲状腺组织炎性减退,边界逐渐清晰。与空白组比较,模型组血清TG-Ab[(79.77±6.06)U/mL比(43.00±9.36)U/mL,P<0.01]、TPO-Ab[(8.04±0.99)U/mL比(2.76±1.11)U/mL,P<0.01]及甲状腺组织Bax mRNA[(1.39±0.09)比(0.27±0.11),P<0.01]表达均升高,甲状腺组织Bcl-2 mRNA[(1.29±0.14)比(3.39±0.37),P<0.01]表达降低。与模型组和安慰剂组比较,当归六黄汤组血清TG-Ab[(43.69±11.51)U/mL比(79.77±6.06)U/mL、(82.17±12.11)U/mL,P<0.01]、TPO-Ab[(3.02±0.73)U/mL比(8.04±0.99)U/mL、(7.84±0.79)U/mL,P<0.01]及甲状腺组织Bax mRNA[(0.24±0.10)比(1.39±0.09)、(1.38±0.34),P<0.01]表达均降低,甲状腺组织Bcl-2 mRNA表达升高[(2.89±0.32)比(1.29±0.14)、(1.36±0.29),P<0.01]。与空白组比较,模型组外周血CD3^(+)T细胞Tyro3、Axl MFI[Tyro3:(1325.53±129.45)比(1775.95±120.73),Axl:(130.10±11.71)比(156.58±9.27),P<0.01]及甲状腺组织Tyro3、Axl mRNA[Tyro3:(0.67±0.13)比(3.06±0.23),Axl:(0.14±0.05)比(0.71±0.17),P<0.01]和平均光密度(AOD)[Tyro3:(119.45±14.47)比(266.20±33.21),Axl:(117.96±13.06)比(240.06±21.50),P<0.01]均降低。与模型组和安慰剂组比较,当归六黄汤组外周血CD3^(+)T细胞Tyro3、Axl MFI[Tyro3:(1769.92±151.90)比(1325.53±129.45)、(1241.57±193.40),Axl:(150.08±15.32)比(130.10±11.71)、(127.50±9.94),P<0.01]及甲状腺组织Tyro3、Axl mRNA[Tyro3:(2.69±0.44)比(0.67±0.13)、(0.71±0.33),Axl:(0.62±0.10)比(0.14±0.05)、(0.12±0.04),P<0.01]和AOD[Tyro3:(251.41±32.28)比(119.45±14.47)、(115.69±24.81),Axl:(223.23±19.12)比(117.96±13.06)、(119.69±20.48),P<0.01]均升高。结论当归六黄汤对桥本甲状腺炎大鼠的抑制效果可能和激活Tyro3/Axl受体信号通路进而引起凋亡抑制有关。 展开更多
关键词 大鼠 桥本甲状腺炎 当归六黄汤 Tyro3/axl受体 B细胞淋巴瘤-2 B细胞淋巴瘤-2相关X蛋白
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Establishment of the thermo-mechanical coupling model of axle box bearings with track irregularity excitation and analysis of its temperature characteristics
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作者 Min WANG Shaopu YANG +2 位作者 Yongqiang LIU Yanhong CHEN Kai ZHANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第11期1965-1986,共22页
As an important component of the running gear of high-speed trains,axle box bearings can cause lubricating grease failure and damage to bearing components under continuous high-temperature operation,which will affect ... As an important component of the running gear of high-speed trains,axle box bearings can cause lubricating grease failure and damage to bearing components under continuous high-temperature operation,which will affect the normal operation of highspeed trains.Therefore,bearing temperature is one of the key parameters to be monitored in the online monitoring system for trains.Based on the thermal network method,this paper establishes a thermal network model for the axle box bearing,considering the radial thermal deformation of the double-row tapered roller bearing components caused by the oil film characteristics and the temperature variations of the lubricating grease.A thermo-mechanical coupling model for the grease-lubricated double-row tapered roller axle box bearing of high-speed trains with track irregularity excitation is established.The correctness of the model is verified using the test bench data,and the temperature of the bearing at different rotational speeds,loads,fault sizes,and ambient temperatures are investigated. 展开更多
关键词 axle box bearing thermal network method TEMPERATURE rotational speed
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Instrumented oscillographic study on impact toughness of an axle steel DZ2 with different tempering temperatures
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作者 Shuo Liu Peng Zhang +6 位作者 Bin Wang Kaizhong Wang Zikuan Xu Fangzhong Hu Xin Bai Qiqiang Duan Zhefeng Zhang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第7期1590-1598,共9页
Compared with the conventional Charpy impact test method,the oscillographic impact test can help in the behavioral analysis of materials during the fracture process.In this study,the trade-off relationship between the... Compared with the conventional Charpy impact test method,the oscillographic impact test can help in the behavioral analysis of materials during the fracture process.In this study,the trade-off relationship between the strength and toughness of a DZ2 axle steel at various tempering temperatures and the cause of the improvement in impact toughness was evaluated.The tempering process dramatically influenced carbide precipitation behavior,which resulted in different aspect ratios of carbides.Impact toughness improved along with the rise in tempering temperature mainly due to the increase in energy required in impact crack propagation.The characteristics of the impact crack propagation process were studied through a comprehensive analysis of stress distribution,oscilloscopic impact statistics,fracture morphology,and carbide morphology.The poor impact toughness of low-tempering-temperature specimens was attributed to the increased number of stress concentration points caused by carbide morphology in the small plastic zone during the propagation process,which resulted in a mixed distribution of brittle and ductile fractures on the fracture surface. 展开更多
关键词 axle steel DZ2 tempering process impact toughness oscillographic impact test impact crack propagation carbides
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补肾通络方调控RANKL-RANK-OPG通路干预破骨细胞相关蛋白的机制研究 被引量:1
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作者 李平顺 田杰祥 +5 位作者 王丽琴 周孟茹 马鹏程 王涛 魏勇 王钢 《时珍国医国药》 北大核心 2025年第1期40-49,共10页
目的观察补肾通络方对胶原诱导性关节炎(CIA)大鼠的疗效,并探讨可能的机制。方法选用SPF级SD雌雄大鼠,按0.3mL(300μg牛II型胶原乳剂)/只,分别在大鼠双侧后足跖皮内、尾跟部皮下致炎,造模成功后随机分为正常组(生理盐水)、模型组(生理盐... 目的观察补肾通络方对胶原诱导性关节炎(CIA)大鼠的疗效,并探讨可能的机制。方法选用SPF级SD雌雄大鼠,按0.3mL(300μg牛II型胶原乳剂)/只,分别在大鼠双侧后足跖皮内、尾跟部皮下致炎,造模成功后随机分为正常组(生理盐水)、模型组(生理盐水)、甲氨蝶呤组(每周1.04mg/kg)、补肾通络方低剂量组[0.31g/(kg·d)]、中剂量组[0.62g/(kg·d)]、高剂量组[1.24g/(kg·d)],连续灌胃8周,每7天检测1次体重、足跖肿胀度,观察各组大鼠一般状态、骨体积分数(BV/TV)、骨小梁厚度(Tb.Th)、骨小梁间隙(Tb.Sp)、骨小梁数量(Tb.N)、膝关节滑膜病理切片等改变;ELISA法检测血清中RANKL、OPG、TNF-α、IL-6、IL-17表达量;Western blot法测定踝关节RANKL、RANK、OPG表达量;R-T PCR法测定踝关节RANKL、RANK、OPG mRNA表达。结果与正常组比较,模型组大鼠生活状态欠佳,体重下降显著,足跖明显肿胀,关节破坏,滑膜明显增厚,Tb.Sp、RANK、RANKL、TNF-α、IL-6、IL-17明显增加,BV/TV、Tb.Th、Tb.N、OPG明显降低(P<0.05);与模型组比较,甲氨蝶呤组与补肾通络方干预组均可明显改善大鼠生活状态欠佳、体重下降、足跖肿胀、滑膜增厚、关节破坏的情况,增加BV/TV、Tb.Th和Tb.N,减少Tb.Sp,下调RANKL/OPG比例及TNF-α、IL-6、IL-17的表达量,并且补肾通络方高剂量组改善效果更加明显(P<0.05)。结论补肾通络方可有效控制CIA大鼠体内炎性程度和骨破坏的发展,对RA有一定的治疗作用,其机制可能与调节RANKL-RANK-OPG信号通路有关。 展开更多
关键词 类风湿关节炎 破骨细胞 骨破坏 rankl-rank-opg信号通路 补肾通络方 分化
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Optimal allocation method of electric/air braking force of high-speed train considering axle load transfer
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作者 Feng Guo Jing He 《High-Speed Railway》 2024年第2期77-84,共8页
Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the probl... Reasonable distribution of braking force is a factor for a smooth,safe,and comfortable braking of trains.A dynamic optimal allocation strategy of electric-air braking force is proposed in this paper to solve the problem of the lack of consideration of adhesion difference of train wheelsets in the existing high-speed train electric-air braking force optimal allocation strategies.In this method,the braking strategy gives priority to the use of electric braking force.The force model of a single train in the braking process is analyzed to calculate the change of adhesion between the wheel and rail of each wheelset after axle load transfer,and then the adhesion of the train is estimated in real time.Next,with the goal of maximizing the total adhesion utilization ratio of trailer/motor vehicles,a linear programming distribution function is constructed.The proportional coefficient of adhesion utilization ratio of each train and the application upper limit of braking force in the function is updated according to the change time point of wheelset adhesion.Finally,the braking force is dynamically allocated.The simulation results of Matlab/Simulink show that the proposed algorithm not only uses the different adhesion limits of each trailer to reduce the total amount of braking force undertaken by the motor vehicle,but also considers the adhesion difference of each wheelset.The strategy can effectively reduce the risk and time of motor vehicles during the braking process and improve the stability of the train braking. 展开更多
关键词 Braking force allocation WHEELSET Dynamicity axle load transfer total Adhesion utilization ratio
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Effect of Seasonal Variations on the Behavior of Flexible Pavements in Burkina Faso: Towards Alternating and Periodic Loading of Multi-Axle Heavy Goods Vehicles for Road Durability
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作者 Kokoro Kobori Doua Allain Gnabahou Bouto Kossi Imbga 《Journal of Materials Science and Chemical Engineering》 2024年第6期24-42,共19页
Bituminous materials are heat-sensitive, and their mechanical properties vary with temperature. This variation in properties is not without consequences on the performance of flexible road structures under the repeate... Bituminous materials are heat-sensitive, and their mechanical properties vary with temperature. This variation in properties is not without consequences on the performance of flexible road structures under the repeated passage of multi-axles. This study determines the influence of seasonal variations on the rate of permanent deformation, the rut depth of flexible pavements and the effect of alternating loading of heavy goods vehicles following the temperature variations on the durability of roads. Thus, an ambient and pavement surface temperature measurement was carried out in 2022. The temperature profile at different layers of the modelled pavement, the evaluation of deformation rates and rutting depth were determined using several models. The results show that the permanent deformation and rutting rates are higher at the level of the bituminous concrete layer than at the level of the asphalt gravel layer because the stresses decrease from the surface to the depth of the pavement. On the other hand, the variations in these rates, permanent deformations and ruts between the hot and so-called cold periods are more pronounced in the bitumen gravel than in bituminous concrete, showing that gravel bitumen is more sensitive to temperature variations than bituminous concrete despite its higher rigidity. Of these results, we suggested a periodic and alternating loading of the different types of heavy goods vehicles. These loads consist of fully applying the WAEMU standards with a tolerance of 15% during periods of high and low temperatures. This regulation has increased 2 to 3 times in the durability of roadways depending on the type of heavy goods vehicle. 展开更多
关键词 PAVEMENT RUTTING Permanent Deformation Multi-axle Seasonal
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Simulation Research on Stress Intensity Factors of Different Crack Aspect Ratios on Hollow Axles 被引量:2
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作者 ZHOU Suxia XIE Jilong 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2009年第5期766-771,共6页
Because of the wicked service environment of the high speed train, it is possible that the hollow axle of the train may encounter the foreign object damage and form a sharp notch. Under the fatigue loading a crack can... Because of the wicked service environment of the high speed train, it is possible that the hollow axle of the train may encounter the foreign object damage and form a sharp notch. Under the fatigue loading a crack can initiate from the notch and propagate to failure. It is noted that the stress intensity factor is the control parameter of the crack propagating, for the purpose of getting the more exact propagation characteristics, the stress intensity factor is studied mainly. The service loads of hollow axles are defined, and the stress distribution of hollow axles is obtained according to the load spectrum. The semi-ellipse crack configuration is defined with three parameters: the aspect ratio, the relative depth and the relative location along the crack front. Quarter point 20-node isoparametric degenerate singular elements are used for the region near the crack tip. The finite element model of crack extension of hollow axle is created, and the crack front is dispersed which can realize orthogonal extension. Based on this the stress intensity factors of crack front were calculated, and the distribution rules of the stress intensity factors of different initial crack shapes are obtained. The conclusions are compared with that of the analytic method and they agree with each other very well, and the calculating results show that there is a close relationship between the stress intensity factor and the initial crack shape. For a round crack the stress intensity factor at the surface point increases faster than the one at the center point with the crock propagation. However, for a narrow crack, the results are in contrast with that of a round one. So, all the cracks with different shapes propagate toward to a similar shape, and they grow at this shape to end. The study may contribute to the crack propagate characteristics research. 展开更多
关键词 hollow axle surface crack propagation stress intensity factor finite element
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Analysis of Quenching Stresses in 35CrMo Axle 被引量:2
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作者 龚海 WU Yunxin +1 位作者 FENG Xiaolei LI Yihua 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2016年第3期630-635,共6页
By using the finite element method (FEM), we comprehensively analyzed the fields of temperature, organization, and stress in 35CrMo train axles during the quenching process is conducted, and experimentally studied t... By using the finite element method (FEM), we comprehensively analyzed the fields of temperature, organization, and stress in 35CrMo train axles during the quenching process is conducted, and experimentally studied the formation and evolution of inner stresses in axles during the quenching process. The results show that in the quenching process, stresses on the axle surface change from tensile to compressive gradually, while stresses in the axle core change from compressive to tensile gradually. Heat stresses and the amount of martensitic transformation are all increased with the increase of cooling rate. As a result, the maximmn instantaneous stresses in the axle are increased greatly when the cooling rate is increased with brine quenching. Large instantaneous tensile stress in the axle core with brine quenching is very likely to cause quench cracking and should be avoided. 展开更多
关键词 35CrMo axle QUENCHING residual stress FEM X-ray diffraction
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Analysis and Optimization on Factors Affecting Forming Quality of Half Axle Gears Warm Precision Forging 被引量:2
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作者 WANG Menghan CHEN Xihou ZHOU Jie 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2010年第1期110-114,共5页
Half axle gears is produced by precision forging popularly because of the advantages in minimum machining allowances, lower material consumption and good service properties. But the forming quality of precision forgin... Half axle gears is produced by precision forging popularly because of the advantages in minimum machining allowances, lower material consumption and good service properties. But the forming quality of precision forging is difficult to control. Many simulations and analysis of precision forging process were taken by previous researchers. But no concrete method is proposed to evaluate and optimize the forming quality of half axel gears. The primary purpose of this work is improving the forming quality of half axel gears by analyzing and optimizing the affected factors of forming quality. The enclosed-die warm forging process of half axle gears was developed, and a new type of die-set used on double action hydraulic press was brought forward. The main influential factors of precision forming quality were analyzed after the forming process had been simulated by using finite element method(FEM). These factors include die structure, web thickness and web position. A method used to evaluate the forming quality was established, which investigated the maximal forming load, the metal filling rate and the material damage factor. The FEM simulations of half axle gears precision forging were evaluated by this method. The results show that the best forming quality can be achieved when the punches were added with bosses, the web located at the middle plant of the gear, and the web thickness was 30 percent of the inner hole diameter. Verification experiments taking the above optimized parameters were performed on a 7.8 MN double action hydraulic press. The trial products were formed well. And their geometric precision meets the demand. The verification result shows that the optimization of the influential factors, according to the simulations and the evaluation method, can improve the forming quality. The new structure of precision forging die-set and the new evaluation method guarantee a high forming quality ofhalfaxel gears. 展开更多
关键词 warm precision forging half axle gears forming quality die structure WEB
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受体酪氨酸激酶AXL在肿瘤生物学中的作用研究进展 被引量:2
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作者 何凯桐 周阳 +2 位作者 王明珠 郭婷 孙轶华 《现代肿瘤医学》 CAS 2024年第1期167-171,共5页
AXL是一种受体酪氨酸激酶(receptor tyrosine kinase,RTK),属于TAM(TYRO3-AXL-MER)家族。在生理条件下,AXL表达于人体的心脏、骨骼肌、甲状腺中。AXL通过调控多条信号通路介导了肿瘤细胞的血管生成、迁移、侵袭、增殖与转移等过程。此外... AXL是一种受体酪氨酸激酶(receptor tyrosine kinase,RTK),属于TAM(TYRO3-AXL-MER)家族。在生理条件下,AXL表达于人体的心脏、骨骼肌、甲状腺中。AXL通过调控多条信号通路介导了肿瘤细胞的血管生成、迁移、侵袭、增殖与转移等过程。此外,AXL在多种癌症中高表达,对于肿瘤患者的预后评价具有重要意义,并极有可能成为一种新的诊断及预后生物标志物和治疗靶点。本文就近年来AXL在肿瘤生物学中的作用研究进展进行综述。 展开更多
关键词 受体酪氨酸激酶 axl 肿瘤 耐药
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DAMAGE TOLERANCE ANALYSIS ON HOLLOW AXLES OF HIGH SPEED MOTOR TRAINS 被引量:2
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作者 ZHOU Suxia XIE Jilong +1 位作者 YANG Guangxue XIAO Nan 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2008年第5期8-12,共5页
According to the rules of UIC515-3,the service loads of the axles are defined,which include some different loads cases as follows:the static loads;the impact loads resulted from running through the rail joints and une... According to the rules of UIC515-3,the service loads of the axles are defined,which include some different loads cases as follows:the static loads;the impact loads resulted from running through the rail joints and unevenness rails;the loads through curves and from braking.Through the calculating and analysis,the stress distribution of the hollow axles is obtained for 200 km/h high speed motor trains used in China.At the same time,the fatigue crack growth of hollow axles is studied,and the initial surface cracks of 2 mm depth caused by hard objects strike or the other causes are discussed.On the basis of the linear elastic fracture mechanics theory,the stress intensity factor of the crack of the geometry transition outside the wheel seat is also studied.Associated with fatigue crack propagation equation and the corresponding crack propagation threshold,the crack propagation characteristics under different shapes are calculated.Then the running distances are educed with different shapes propagating to the critical length,and the estimation of the residual lives about hollow axles which are the reference values of examine and repair limit of the hollow axle is given. 展开更多
关键词 Motor wains Hollow railway axles Fatigue crack axle stress Damage tolerance Loads
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Experimental and numerical study on fretting wear and fatigue of full-scale railway axles 被引量:14
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作者 Lang Zou Dongfang Zeng +3 位作者 Yabo Li Kai Yang Liantao Lu Caiqin Yuan 《Railway Engineering Science》 2020年第4期365-381,共17页
This study investigated the fretting wear and fatigue of full-scale railway axles.Fatigue tests were conducted on full-scale railway axles,and the fretting wear and fretting fatigue in the fretted zone of the railway ... This study investigated the fretting wear and fatigue of full-scale railway axles.Fatigue tests were conducted on full-scale railway axles,and the fretting wear and fretting fatigue in the fretted zone of the railway axles were analysed.Three-dimensional finite element models were established based on the experimental results.Then,multi-axial fatigue parameters and a linear elastic fracture mechanics-based approach were used to investigate the fretting fatigue crack initiation and propagation,respectively,in which the role of the fretting wear was taken into account.The experimental and simulated results showed that the fretted zone could be divided into zones I-III according to the surface damage morphologies.Fretting wear alleviated the stress concentration near the wheel seat edge and resulted in a new stress concentration near the worn/unworn boundary in zone II,which greatly promoted the fretting crack initiation at the inner side of the fretted zone.Meanwhile,the stress concentration also increased the equivalent stress intensity factor range DKeq below the mating surface,and thus promoted the propagation of fretting fatigue crack.Based on these findings,the effect of the stress redistribution resulting from fretting wear is suggested to be taken into account when evaluating the fretting fatigue in railway axles. 展开更多
关键词 Railway axle Fretting wear Fretting fatigue Crack initiation Crack propagation Finite element
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Fatigue Properties Improvement of Low-Carbon Alloy Axle Steel by Induction Hardening and Shot Peening:A Prospective Comparison 被引量:4
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作者 G.C.Chu F.Z.Hu +4 位作者 X.J.jin Y.Zhang Q.Wang J.P.Hou Z.F.Zhang 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2022年第8期1343-1356,共14页
Fatigue fracture is the major threat to the railway axle, which can be avoided or delayed by surface strengthening. In this study, a low-carbon alloy axle steel with two states was treated by surface induction hardeni... Fatigue fracture is the major threat to the railway axle, which can be avoided or delayed by surface strengthening. In this study, a low-carbon alloy axle steel with two states was treated by surface induction hardening and shot peening, respectively, to reveal the mechanism of fatigue property improvement by microstructure characterization, microhardness measurement, residual stress analysis, roughness measurement, and rotary bending fatigue tests. The results indicate that both quenching and tempering treatment can effectively improve the fatigue properties of the modified axle steel. In addition, induction hardening can create an ideal hardened layer on the sample surface by phase transformation from the microstructure of ferrite and pearlite to martensite. By comparison, shot peening can modify the microstructure in surface layer by surface severe plastic deformation introducing a large number of dislocation and even cause grain refinement. Both induction hardening and shot peening create compressive residual stress into the surface layer of axle steel sample, which can effectively reduce the stress level applied to the metal surface during the rotary bending fatigue tests. On the whole, the contribution of induction hardening to the fatigue life of axle steel sample is better than that of the shot peening, and induction hardening shows obvious advantages in improving the fatigue life of axle steel. 展开更多
关键词 Surface strengthening Induction hardening Shot peening axle steel Fatigue property improvement
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Vibration of Axle Box from Wheel Diameter Difference in Vehicle 被引量:3
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作者 CHENG Daolai XU Lei SUN Xiaojie 《Journal of Shanghai Jiaotong university(Science)》 EI 2020年第4期509-518,共10页
The wheel diameter difference would worsen the dynamic performance and affect the safety of the rail vehicle.Therefore,it is necessary to detect wheel diameter difference while the train is operating.However,several e... The wheel diameter difference would worsen the dynamic performance and affect the safety of the rail vehicle.Therefore,it is necessary to detect wheel diameter difference while the train is operating.However,several existing detection methods can’t accurately detect and diagnose the wheel diameter difference under highspeed running environment.In this study,a new method of detecting wheel diameter difference was proposed for high speed rail vehicle.The wheel diameter difference would be diagnosed by the amplitude and frequency of vibration impact on the axle box.Firstly,the dynamic model with varying wheel diameters was established in SIMPACK,and LMA tread was used in high-speed rail vehicles.Then,the simulation results of rail vehicle dynamic performance were compared under different wheel diameter differences.After that,the relationship between axle box vibration and wheel diameter difference was used to demonstrate the feasibility of this detection technology.Finally,comparing and analyzing the simulation results of vibration obtained by matching treads with different wheel diameters,it shows that by increasing the wheel diameter difference,the longitudinal and lateral impacts on axle boxes increase asymmetrically,and the amplitude and the frequency become more evident.Therefore,this paper presents a technical scheme of online measuring wheel diameter difference by monitoring the vibration of the axle box. 展开更多
关键词 wheel diameter difference axle box dynamic simulation vibration characteristics
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