Xu et al retrospectively assessed endoscopic resection(ER)for esophageal gastrointestinal stromal tumors(E-GISTs)and reported excellent 5-year survival rates.Although ER shows promise as a minimally invasive procedure...Xu et al retrospectively assessed endoscopic resection(ER)for esophageal gastrointestinal stromal tumors(E-GISTs)and reported excellent 5-year survival rates.Although ER shows promise as a minimally invasive procedure,the 75%R0 resection rate with recurrence observed even after R0 resection warrants further discussion.We highlight the need for careful patient selection based on tumor size,location,and risk,considering endoscopic and thoracoscopic approaches.Future studies should refine ER techniques,optimize patient selection,and establish long-term follow-up to guide E-GIST management.展开更多
1文献来源Pezzi TA,Mohamed ASR,Fuller CD,et al.Radiation therapy is independently associated with worse survival after R0-resection for stageⅠ~Ⅱnon-small cell lung cancer:An analysis of the National Cancer Data Base[...1文献来源Pezzi TA,Mohamed ASR,Fuller CD,et al.Radiation therapy is independently associated with worse survival after R0-resection for stageⅠ~Ⅱnon-small cell lung cancer:An analysis of the National Cancer Data Base[J].Ann Surg Oncol,2017,24(5):1419-1427.2证据水平2a。3背景1998年发表的一篇针对肺癌术后放射治疗的荟萃分析显示,Ⅰ~Ⅱ期手术切除的非小细胞肺癌(non-small cell lung cancer,NSCLC)患者接受术后放射治疗(postoperative radiotherapy,PORT)与更差的生存预后相关,但考虑与当时落后的放疗仪器及技术也有一定关系。已有利用美国国家癌症数据库(National Cancer Data Base,NCDB)的真实世界研究发现pN2的NSCLC患者行PORT能够获得生存获益,因此,本文旨在运用该数据库分析早期(Ⅰ~Ⅱ期)NSCLC行PORT获益情况。随着放疗仪器及技术改进后,R0切除的Ⅰ~Ⅱ期NSCLC行PORT与预后关系尚未可知。展开更多
文摘Xu et al retrospectively assessed endoscopic resection(ER)for esophageal gastrointestinal stromal tumors(E-GISTs)and reported excellent 5-year survival rates.Although ER shows promise as a minimally invasive procedure,the 75%R0 resection rate with recurrence observed even after R0 resection warrants further discussion.We highlight the need for careful patient selection based on tumor size,location,and risk,considering endoscopic and thoracoscopic approaches.Future studies should refine ER techniques,optimize patient selection,and establish long-term follow-up to guide E-GIST management.
文摘1文献来源Pezzi TA,Mohamed ASR,Fuller CD,et al.Radiation therapy is independently associated with worse survival after R0-resection for stageⅠ~Ⅱnon-small cell lung cancer:An analysis of the National Cancer Data Base[J].Ann Surg Oncol,2017,24(5):1419-1427.2证据水平2a。3背景1998年发表的一篇针对肺癌术后放射治疗的荟萃分析显示,Ⅰ~Ⅱ期手术切除的非小细胞肺癌(non-small cell lung cancer,NSCLC)患者接受术后放射治疗(postoperative radiotherapy,PORT)与更差的生存预后相关,但考虑与当时落后的放疗仪器及技术也有一定关系。已有利用美国国家癌症数据库(National Cancer Data Base,NCDB)的真实世界研究发现pN2的NSCLC患者行PORT能够获得生存获益,因此,本文旨在运用该数据库分析早期(Ⅰ~Ⅱ期)NSCLC行PORT获益情况。随着放疗仪器及技术改进后,R0切除的Ⅰ~Ⅱ期NSCLC行PORT与预后关系尚未可知。
