BACKGROUND Rectal cancer requires accurate preoperative assessment of T stage and differentiation grade for treatment planning.Traditional imaging and serum markers have limitations in diagnostic accuracy.AIM To evalu...BACKGROUND Rectal cancer requires accurate preoperative assessment of T stage and differentiation grade for treatment planning.Traditional imaging and serum markers have limitations in diagnostic accuracy.AIM To evaluate the predictive value of dynamic contrast-enhanced-magnetic resonance imaging(DCE-MRI)parameters and serum biomarkers[carbohydrate antigen(CA)19-9,CA125]for determining T stage and differentiation grade in rectal cancer.METHODS We conducted a retrospective review of clinical data from 126 patients who were pathologically diagnosed with rectal cancer between January 2021 to June 2024.Each patient underwent DCE-MRI scans and serum tests for CA19-9 and CA125.Receiver operating characteristic curves were utilized to assess the diagnostic value of DCE-MRI parameters,including volume transfer constant(Ktrans),rate constant(Kep),and volume fraction of extravascular extracellular space(Ve),as well as serum biomarkers for staging and grading rectal cancer.The DeLong test algorithm was employed to evaluate differences in diagnostic performance among the various indicators.RESULTS There were statistically higher levels of Ktrans,Ve,CA19-9,and CA125 serum concentrations of patients with advanced T stages and on poorly differentiated tumors than that in patients with low stages and moderate to high differentiation(P<0.05).Combined use of Ktrans and Ve for T stage diagnosis showed an area under the curve(AUC)of 0.892[95%confidence interval(CI):0.832-0.952],which increased to 0.923(95%CI:0.865-0.981)when combined with serum biomarkers.For grades differentiation,the combined DCE-MRI parameters had an AUC of 0.883(95%CI:0.821-0.945),which rose to 0.912(95%CI:0.855-0.969)when combined with serum markers.According to the Delong test,the combined diagnostic method performed better than a single diagnostic method(P<0.05).CONCLUSION The combined application of DCE-MRI functional parameters and serum tumor markers can significantly improve the diagnostic accuracy of T staging and differentiation degree of rectal cancer,providing a new approach to improve the preoperative assessment system of rectal cancer.This combined diagnostic model has important clinical application value,but further validation is needed through large-scale multicenter studies.展开更多
The environmental background values of 13 elements of Hg, As, Se, Cr,Mn, V, Ph, Cd, Zn, Cu, Ni, F and Co in xizang soils are obtained through analyzing and determining 205 samples of surface soils in Tibet and the fin...The environmental background values of 13 elements of Hg, As, Se, Cr,Mn, V, Ph, Cd, Zn, Cu, Ni, F and Co in xizang soils are obtained through analyzing and determining 205 samples of surface soils in Tibet and the final data processing. The background val展开更多
In this paper, by means of the definition of Borel exceptional value method, another exceptional value of meromorphic function which is a T exceptional value is defined by linking the concept of T direction. And we co...In this paper, by means of the definition of Borel exceptional value method, another exceptional value of meromorphic function which is a T exceptional value is defined by linking the concept of T direction. And we construct a meromorphic function with zero as Borel exceptional value, but not as T exceptional value; and another meromorphic function with zero as T exceptional value, but not as Borel exceptional value.展开更多
The researches on the assessment of earthquake forecast are reviewed, then the R-value assessment is further developed theoretically in the paper. The results include the arithmetic of the R-values of earthquake occur...The researches on the assessment of earthquake forecast are reviewed, then the R-value assessment is further developed theoretically in the paper. The results include the arithmetic of the R-values of earthquake occurrence under the condition that 'anomaly' occurred or no 'anomaly' occurred respectively, and the relation between the values. The distribution of Rvalue of a forecast method, corresponding to multi-status anomalies being independent each other, is also developed in the paper. The appropriate methods to estimate the R-values and extrapolate the occurrence probability of future earthquakes are also given in the paper.展开更多
The China’s Conversion Cropland to Forest Program(CCFP)is one of the largest national ecological construction programs,which has effectively improved ecological environment and produced large ecological benefi t.To p...The China’s Conversion Cropland to Forest Program(CCFP)is one of the largest national ecological construction programs,which has effectively improved ecological environment and produced large ecological benefi t.To provide references for further improving ecological benefi t of CCFP,we analyzed the features,differences and relationships of the categorized forest ecological“benefi t value”(B-V)s in 3 kinds of forest restoration ways in different regions in CCFP,using the data of Chinese Forest Ecosystem Research Network(CFERN)from 1999 to 2013 and the methods of the national standards of(LY/T1606-2003),(LY/T1721-2008)and(LY/T1952-2011).The result showed that annual B-Vs of unit area varied in the range of 3.5-10.0 e4 RMBs/hm2·a.Water conservation B-Vs and species conservation B-Vs are the 2 largest constituents,nutrient accumulation B-V was the least in total B-Vs.The B-Vs performed inconsistently among the forest restoration ways and different regions.The rank of average annual total B-Vs of unit area from high to low was“hillside forest conservation”,“returning cropland to forest”,“afforestation on suitable barren hills and wasteland”.Species conservation B-Vs and water conservation B-Vs in southern regions were higher than that of northern and northwestern regions in China.The hot and rainy regions could produce higher species conservation B-Vs.The regression analysis indicated that water conservation B-Vs had signifi cantly positive correlation with the relevant total B-Vs and positive correlation with the relevant atmosphere purification B-Vs whether in regional or in unit area scale.Unit area species conservation B-V was negatively correlated with the relevant nutrient accumulation B-Vs except the way of“afforestation on suitable barren hills and wasteland”.Regional total species conservation B-Vs had signifi cantly negative correlation with its relevant nutrient accumulation B-Vs except“hillside forest conservation”way.We suggest that suitable forest restoration ways must be selective according to the regional specifi c,B-V features and local ecological goals.展开更多
文摘BACKGROUND Rectal cancer requires accurate preoperative assessment of T stage and differentiation grade for treatment planning.Traditional imaging and serum markers have limitations in diagnostic accuracy.AIM To evaluate the predictive value of dynamic contrast-enhanced-magnetic resonance imaging(DCE-MRI)parameters and serum biomarkers[carbohydrate antigen(CA)19-9,CA125]for determining T stage and differentiation grade in rectal cancer.METHODS We conducted a retrospective review of clinical data from 126 patients who were pathologically diagnosed with rectal cancer between January 2021 to June 2024.Each patient underwent DCE-MRI scans and serum tests for CA19-9 and CA125.Receiver operating characteristic curves were utilized to assess the diagnostic value of DCE-MRI parameters,including volume transfer constant(Ktrans),rate constant(Kep),and volume fraction of extravascular extracellular space(Ve),as well as serum biomarkers for staging and grading rectal cancer.The DeLong test algorithm was employed to evaluate differences in diagnostic performance among the various indicators.RESULTS There were statistically higher levels of Ktrans,Ve,CA19-9,and CA125 serum concentrations of patients with advanced T stages and on poorly differentiated tumors than that in patients with low stages and moderate to high differentiation(P<0.05).Combined use of Ktrans and Ve for T stage diagnosis showed an area under the curve(AUC)of 0.892[95%confidence interval(CI):0.832-0.952],which increased to 0.923(95%CI:0.865-0.981)when combined with serum biomarkers.For grades differentiation,the combined DCE-MRI parameters had an AUC of 0.883(95%CI:0.821-0.945),which rose to 0.912(95%CI:0.855-0.969)when combined with serum markers.According to the Delong test,the combined diagnostic method performed better than a single diagnostic method(P<0.05).CONCLUSION The combined application of DCE-MRI functional parameters and serum tumor markers can significantly improve the diagnostic accuracy of T staging and differentiation degree of rectal cancer,providing a new approach to improve the preoperative assessment system of rectal cancer.This combined diagnostic model has important clinical application value,but further validation is needed through large-scale multicenter studies.
文摘The environmental background values of 13 elements of Hg, As, Se, Cr,Mn, V, Ph, Cd, Zn, Cu, Ni, F and Co in xizang soils are obtained through analyzing and determining 205 samples of surface soils in Tibet and the final data processing. The background val
基金supported by the Natural Science Foundation of China(10161006)
文摘In this paper, by means of the definition of Borel exceptional value method, another exceptional value of meromorphic function which is a T exceptional value is defined by linking the concept of T direction. And we construct a meromorphic function with zero as Borel exceptional value, but not as T exceptional value; and another meromorphic function with zero as T exceptional value, but not as Borel exceptional value.
基金a result of a project sponsored by the China Seismological Bureau (95-04-07-04-01).
文摘The researches on the assessment of earthquake forecast are reviewed, then the R-value assessment is further developed theoretically in the paper. The results include the arithmetic of the R-values of earthquake occurrence under the condition that 'anomaly' occurred or no 'anomaly' occurred respectively, and the relation between the values. The distribution of Rvalue of a forecast method, corresponding to multi-status anomalies being independent each other, is also developed in the paper. The appropriate methods to estimate the R-values and extrapolate the occurrence probability of future earthquakes are also given in the paper.
基金Hebei Provincial Science&Technology Supporting Program(No.15227652D)Guided by Observation Methodology for Long-term Forest Ecosystem Research of National Standards of the People’s Republic of China(GB/T 33027-2016).
文摘The China’s Conversion Cropland to Forest Program(CCFP)is one of the largest national ecological construction programs,which has effectively improved ecological environment and produced large ecological benefi t.To provide references for further improving ecological benefi t of CCFP,we analyzed the features,differences and relationships of the categorized forest ecological“benefi t value”(B-V)s in 3 kinds of forest restoration ways in different regions in CCFP,using the data of Chinese Forest Ecosystem Research Network(CFERN)from 1999 to 2013 and the methods of the national standards of(LY/T1606-2003),(LY/T1721-2008)and(LY/T1952-2011).The result showed that annual B-Vs of unit area varied in the range of 3.5-10.0 e4 RMBs/hm2·a.Water conservation B-Vs and species conservation B-Vs are the 2 largest constituents,nutrient accumulation B-V was the least in total B-Vs.The B-Vs performed inconsistently among the forest restoration ways and different regions.The rank of average annual total B-Vs of unit area from high to low was“hillside forest conservation”,“returning cropland to forest”,“afforestation on suitable barren hills and wasteland”.Species conservation B-Vs and water conservation B-Vs in southern regions were higher than that of northern and northwestern regions in China.The hot and rainy regions could produce higher species conservation B-Vs.The regression analysis indicated that water conservation B-Vs had signifi cantly positive correlation with the relevant total B-Vs and positive correlation with the relevant atmosphere purification B-Vs whether in regional or in unit area scale.Unit area species conservation B-V was negatively correlated with the relevant nutrient accumulation B-Vs except the way of“afforestation on suitable barren hills and wasteland”.Regional total species conservation B-Vs had signifi cantly negative correlation with its relevant nutrient accumulation B-Vs except“hillside forest conservation”way.We suggest that suitable forest restoration ways must be selective according to the regional specifi c,B-V features and local ecological goals.
文摘基于广义约化R矩阵理论,使用RAC程序(R-matrix analysis code)综合分析了^(6)He系统中所有可以利用的实验数据,给出了氚核入射10-2—20 MeV能量范围内主要反应道的评价核数据.其中积分截面包括T(t,2n)^(4)He,T(t,n)^(5)He,T(t,d)^(4)H;微分截面包括T(t,2n)^(4)He,T(t,n)^(5)He,T(t,d)^(4)H,T(t,t)T.结果表明,RAC的评价结果与实验数据和ENDF/B-Ⅷ.1的评价数据整体符合良好.重点关注T(t,2n)^(4)He反应,评价值在10^(-2)—20 MeV范围内与已有实验数据一致,在2.9 Me V附近出现由2+能级主导的共振,在1.9 Me V处,已有实验同时测量了积分截面和角分布,本工作的评价结果在两类数据上均表现出良好的一致性,积分截面与微分截面的联合约束有效提升了R矩阵参数的稳定性和评价结果的可靠性.基于6He系统的整体评价,进一步补充了T(t,n)^(5)He和T(t,d)^(4)H反应的截面数据.本工作完善了聚变反应相关的数据基础,并为后续与镜像系统6Be系统的联合分析奠定了基础.
