BACKGROUND Platelet-rich plasma(PRP)injection is used as an alternative non-operative management for de Quervain’s tenosynovitis(DQT)to regenerate tendon healing.AIM To assess and conclude the research-based study sy...BACKGROUND Platelet-rich plasma(PRP)injection is used as an alternative non-operative management for de Quervain’s tenosynovitis(DQT)to regenerate tendon healing.AIM To assess and conclude the research-based study systematically to analyse the efficacy of PRP on DQT.METHODS This systematic review used the Cochrane Handbook for Systematic Reviews and the guideline of preferred reporting items for systematic review and metaanalysis.A systematic literature search was applied to 11 databases.The authors assessed the study quality and risk of bias of each included study.Results of the meta-analysis were presented using mean difference(MD)/standardized mean difference(SMD)and 95%condence interval(CI).RESULTS The authors evaluated 275 studies found in the literature search;12 studies met the criteria for this review,and then the study quality and risk of bias were assessed.Pooled analysis of data from two studies involving 194 subjects with DQT showed that,compared with conservative treatment,PRP injection was associated with a greater reduction in visual analog scale pain in one month and six months after treatment(MD:-0.67,P value<0.00001;MD:-1.16,P value<0.00001)and the increase of Mayo’s wrist score in one month and six months after treatment(SMD:3.72,P value<0.00001;SMD:4.44,P value<0.00001).CONCLUSION PRP can be used as an alternative non-operative treatment for DQT due to the tissue regenerative effect of PRP.展开更多
Introduction: De Quervain’s subacute thyroiditis is an inflammatory granulomatosis with clinical presentation some time atypical leading eventually to misdiagnosis or inadequate treatment. In our area, physician shou...Introduction: De Quervain’s subacute thyroiditis is an inflammatory granulomatosis with clinical presentation some time atypical leading eventually to misdiagnosis or inadequate treatment. In our area, physician should be aware of this possible etiology in presence of recent and acute features of thyrotoxicosis with or without painful firm goiter. We illustrate this fact with two new observations from Sub-Saharan Africa. Observations: Our first patient is a 70-year-old Guinean woman presenting a painful nodular and hard goiter at palpation. Her history was recent in a context of deterioration of the general state with a sub clinical thyrotoxicosis syndrome. The diagnosis of probable malignant thyroid tumor was evoked initially and a thyroidectomy considered. She presented an important biological inflammatory syndrome and biological peripheral hyperthyroidism. Neck ultrasound examination showed heterogeneous patchy decreased echogenicity. The diagnosis of subacute De Quervain’s thyroiditis was set up. A corticosteroid therapy at a rate of 20 mg/day of prednisone was begun with a fast degression of dose. After 3 weeks of treatment, we noticed total clinical recovery normalization of biological parameters. The second observation was about a 52-year-old Senegalese women living in Bamako. She presented cervical pains evolving for 2 months in a context of flu-like syndrome associated with thyrotoxicosis and marked biological inflammatory syndrome. The thyroid ultrasound showed global heterogeneity with characteristic aspect of “geography map” leading to the diagnosis of subacute thyroiditis. A combination therapy with low dose of prednisone, ß-blockers and tranquillizers. We noticed fast disappearance of clinical and biological signs. At 5 mg per day of prednisone, there were moderate signs of relapse with rapid favorable evolution after few days under increased dose of prednisone up to 10 mg/day. Conclusion: De Quervain’s thyroiditis can appear under misleading features opening out to make wandering diagnosis. A good clinical evaluation coupled with hormonal and ultrasound thyroid examination may help for right management. The use of low dose of corticosteroid had enabled us to obtain a fast control of main clinical and biological abnormalities.展开更多
Objective:To observe the effect of the treatment of tendon-regulation and bone-setting manipulation and Kinesio Taping on patients with de Quervain Disease.Methods:60 cases with de Quervain Disease were divided into 3...Objective:To observe the effect of the treatment of tendon-regulation and bone-setting manipulation and Kinesio Taping on patients with de Quervain Disease.Methods:60 cases with de Quervain Disease were divided into 30 treatment group and 30 control group according to random number table.The observation group was treated withtendon-regulation and bone-setting manipulation and Kinesio Taping,and the control group was given Votalin emulsion combined with Kinesio Taping.The patients were evaluated and compared according to the VAS before and after treatment,the degree of tenderness,the methods of electric integral value(integral electromyogram,iEMG),the degree of wrist ulnar deviation,and the cooney wrist score,and the curative effect was observed using the diagnostic curative effect criteria of TCM disease(the evaluation process was blinded).Results:Compared with the same group before treatment,after treatment,the pain and tenderness of the two groups were reduced,iEMG value increased,the ulnar deviation of the wrist increased,and the cooney wrist score increased(all P<0.05);the improvement of the treatment group was significantly better.In the control group,the difference was statistically significant(P<0.05)and the total effective rate of the treatment group was 93%higher than that of the control group 80%(P<0.05).Conclusion:The combination of the tendon-regulation and bone-setting manipulation combined with the Kinesio Taping can effectively reduce the pain and tenderness of the patients withde Quervain Disease,increase the ulnar mobility of the wrist joint,and improve the joint function of the wrist joint.展开更多
文摘BACKGROUND Platelet-rich plasma(PRP)injection is used as an alternative non-operative management for de Quervain’s tenosynovitis(DQT)to regenerate tendon healing.AIM To assess and conclude the research-based study systematically to analyse the efficacy of PRP on DQT.METHODS This systematic review used the Cochrane Handbook for Systematic Reviews and the guideline of preferred reporting items for systematic review and metaanalysis.A systematic literature search was applied to 11 databases.The authors assessed the study quality and risk of bias of each included study.Results of the meta-analysis were presented using mean difference(MD)/standardized mean difference(SMD)and 95%condence interval(CI).RESULTS The authors evaluated 275 studies found in the literature search;12 studies met the criteria for this review,and then the study quality and risk of bias were assessed.Pooled analysis of data from two studies involving 194 subjects with DQT showed that,compared with conservative treatment,PRP injection was associated with a greater reduction in visual analog scale pain in one month and six months after treatment(MD:-0.67,P value<0.00001;MD:-1.16,P value<0.00001)and the increase of Mayo’s wrist score in one month and six months after treatment(SMD:3.72,P value<0.00001;SMD:4.44,P value<0.00001).CONCLUSION PRP can be used as an alternative non-operative treatment for DQT due to the tissue regenerative effect of PRP.
文摘Introduction: De Quervain’s subacute thyroiditis is an inflammatory granulomatosis with clinical presentation some time atypical leading eventually to misdiagnosis or inadequate treatment. In our area, physician should be aware of this possible etiology in presence of recent and acute features of thyrotoxicosis with or without painful firm goiter. We illustrate this fact with two new observations from Sub-Saharan Africa. Observations: Our first patient is a 70-year-old Guinean woman presenting a painful nodular and hard goiter at palpation. Her history was recent in a context of deterioration of the general state with a sub clinical thyrotoxicosis syndrome. The diagnosis of probable malignant thyroid tumor was evoked initially and a thyroidectomy considered. She presented an important biological inflammatory syndrome and biological peripheral hyperthyroidism. Neck ultrasound examination showed heterogeneous patchy decreased echogenicity. The diagnosis of subacute De Quervain’s thyroiditis was set up. A corticosteroid therapy at a rate of 20 mg/day of prednisone was begun with a fast degression of dose. After 3 weeks of treatment, we noticed total clinical recovery normalization of biological parameters. The second observation was about a 52-year-old Senegalese women living in Bamako. She presented cervical pains evolving for 2 months in a context of flu-like syndrome associated with thyrotoxicosis and marked biological inflammatory syndrome. The thyroid ultrasound showed global heterogeneity with characteristic aspect of “geography map” leading to the diagnosis of subacute thyroiditis. A combination therapy with low dose of prednisone, ß-blockers and tranquillizers. We noticed fast disappearance of clinical and biological signs. At 5 mg per day of prednisone, there were moderate signs of relapse with rapid favorable evolution after few days under increased dose of prednisone up to 10 mg/day. Conclusion: De Quervain’s thyroiditis can appear under misleading features opening out to make wandering diagnosis. A good clinical evaluation coupled with hormonal and ultrasound thyroid examination may help for right management. The use of low dose of corticosteroid had enabled us to obtain a fast control of main clinical and biological abnormalities.
基金Key project of the Natural Foundation of the Department of Education of Anhui Province(No.KJ2018A0273)。
文摘Objective:To observe the effect of the treatment of tendon-regulation and bone-setting manipulation and Kinesio Taping on patients with de Quervain Disease.Methods:60 cases with de Quervain Disease were divided into 30 treatment group and 30 control group according to random number table.The observation group was treated withtendon-regulation and bone-setting manipulation and Kinesio Taping,and the control group was given Votalin emulsion combined with Kinesio Taping.The patients were evaluated and compared according to the VAS before and after treatment,the degree of tenderness,the methods of electric integral value(integral electromyogram,iEMG),the degree of wrist ulnar deviation,and the cooney wrist score,and the curative effect was observed using the diagnostic curative effect criteria of TCM disease(the evaluation process was blinded).Results:Compared with the same group before treatment,after treatment,the pain and tenderness of the two groups were reduced,iEMG value increased,the ulnar deviation of the wrist increased,and the cooney wrist score increased(all P<0.05);the improvement of the treatment group was significantly better.In the control group,the difference was statistically significant(P<0.05)and the total effective rate of the treatment group was 93%higher than that of the control group 80%(P<0.05).Conclusion:The combination of the tendon-regulation and bone-setting manipulation combined with the Kinesio Taping can effectively reduce the pain and tenderness of the patients withde Quervain Disease,increase the ulnar mobility of the wrist joint,and improve the joint function of the wrist joint.
