Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were rando...Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were randomized into an acupuncture group and a control group,with 30 cases in each group.In the acupuncture group,patients were treated with acupuncture at Quchi(LI11)twice a week for six weeks.In the control group,each patient received a placebo treatment(sham acupuncture).Before and after the intervention,the pruritis severity was examined using a 5-D scale,and the serum IL-2 level was measured using an enzyme-linked immunosorbent assay kit.Results There were no statistically significant differences in the demographic or clinical factors between the control group and the acupuncture group at baseline.The reduction in pruritus severity in patients was more significant in the acupuncture group(P=0.027).Acupuncture therapy also significantly decreased the serum IL-2 level in the patients(P=0.011).Throughout the acupuncture procedures,the incidence of pain and mild bleeding was 3.6%and 2.5%,respectively.Conclusion Six-week acupuncture treatment at Quchi(LI11)can effectively decrease the severity of UP and the serum IL-2 level.Large-scale,long-duration,and multi-center studies are needed to fully understand the role of IL-2 in inflammation and neuroimmune stimulation during acupuncture.展开更多
Objective To compare therapeutic effects of electroacupuncture and western medicine on blood pressure variability in young patients with hypertension. Methods Sixty cases of young patients of hypertension were randoml...Objective To compare therapeutic effects of electroacupuncture and western medicine on blood pressure variability in young patients with hypertension. Methods Sixty cases of young patients of hypertension were randomly divided into an electroacupuncture group and a western medicine group, 30 cases in each group. In the electroacupuncture group, electroacupuncture was applied at Quchi （曲池LI 11） and Taichong （太冲LR 3）. In the western medicine group, Captopril was taken orally. Twenty-four hour dynamic blood pressure, and blood pressure variability and circadian rhythms were observed after treatment for 14 days in the two groups. Results Electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） significantly decreased systolic pressure and diastolic pressure at different time phases in the young patients with hypertension （all P〈0.01）, with no significant difference as compared with the western medicine group （all P〉0.05）; electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） significantly reduced the standard deviations of systolic pressure and diastolic pressure at different time phases in the young patients with hypertension as compared with those before the treatment （P〈0.01, P〈0.05）. There were statistically significant differences between the two groups in 24 h systolic standard deviation （24 h SSD）, 24 h diastolic standard deviation （24 h DSD）, daytime SSD （dSSD）, nighttime SSD （nSSD） and nighttime DSD （nDSD） （P〈0.01, P〈0.05）; and there was significant difference between the two groups in numbers of the Dipper and the non-Dipper after treatment （P〈0.05）. Conclusion Electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） has a better long-term effect of decreasing blood pressure and improves effectively changes of circadian rhythms in young patients with hypertension, which are an effective point pair for hypertension.展开更多
文摘Objective To observe the effect of acupuncture at Quchi(LI11)on the serum interleukin-2(IL-2)level and the severity of uremic pruritus(UP)in hemodialysis patients.Methods Sixty hemodialysis patients with UP were randomized into an acupuncture group and a control group,with 30 cases in each group.In the acupuncture group,patients were treated with acupuncture at Quchi(LI11)twice a week for six weeks.In the control group,each patient received a placebo treatment(sham acupuncture).Before and after the intervention,the pruritis severity was examined using a 5-D scale,and the serum IL-2 level was measured using an enzyme-linked immunosorbent assay kit.Results There were no statistically significant differences in the demographic or clinical factors between the control group and the acupuncture group at baseline.The reduction in pruritus severity in patients was more significant in the acupuncture group(P=0.027).Acupuncture therapy also significantly decreased the serum IL-2 level in the patients(P=0.011).Throughout the acupuncture procedures,the incidence of pain and mild bleeding was 3.6%and 2.5%,respectively.Conclusion Six-week acupuncture treatment at Quchi(LI11)can effectively decrease the severity of UP and the serum IL-2 level.Large-scale,long-duration,and multi-center studies are needed to fully understand the role of IL-2 in inflammation and neuroimmune stimulation during acupuncture.
基金Supported by Project of Shandong Provincial 2005–2006 TCM Science and Technology Development Plan:2005-206
文摘Objective To compare therapeutic effects of electroacupuncture and western medicine on blood pressure variability in young patients with hypertension. Methods Sixty cases of young patients of hypertension were randomly divided into an electroacupuncture group and a western medicine group, 30 cases in each group. In the electroacupuncture group, electroacupuncture was applied at Quchi （曲池LI 11） and Taichong （太冲LR 3）. In the western medicine group, Captopril was taken orally. Twenty-four hour dynamic blood pressure, and blood pressure variability and circadian rhythms were observed after treatment for 14 days in the two groups. Results Electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） significantly decreased systolic pressure and diastolic pressure at different time phases in the young patients with hypertension （all P〈0.01）, with no significant difference as compared with the western medicine group （all P〉0.05）; electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） significantly reduced the standard deviations of systolic pressure and diastolic pressure at different time phases in the young patients with hypertension as compared with those before the treatment （P〈0.01, P〈0.05）. There were statistically significant differences between the two groups in 24 h systolic standard deviation （24 h SSD）, 24 h diastolic standard deviation （24 h DSD）, daytime SSD （dSSD）, nighttime SSD （nSSD） and nighttime DSD （nDSD） （P〈0.01, P〈0.05）; and there was significant difference between the two groups in numbers of the Dipper and the non-Dipper after treatment （P〈0.05）. Conclusion Electroacupuncture at Quchi （曲池LI 11） and Taichong （太冲LR 3） has a better long-term effect of decreasing blood pressure and improves effectively changes of circadian rhythms in young patients with hypertension, which are an effective point pair for hypertension.
