The aim of this study was to develop a novel pharmaceutical excipient:an anion exchange resin.Initially,polystyrenedivinylbenzene(PS-DVB)microspheres were synthesized via suspension polymerization.Subsequently,these m...The aim of this study was to develop a novel pharmaceutical excipient:an anion exchange resin.Initially,polystyrenedivinylbenzene(PS-DVB)microspheres were synthesized via suspension polymerization.Subsequently,these microspheres served as a substrate for chloromethylation using methanol,formaldehyde,and chlorosulfonic acid.By optimizing the reaction conditions,the chloromethylated microspheres were characterized using infrared spectroscopy,scanning electron microscopy,and the Mohr method.Under optimal reaction conditions,the resulting products exhibited uniformity and spherical morphology,with an average particle size of approximately 190μm.The PS-DVB microspheres effectively incorporated chloromethyl groups,as evidenced by a chlorine content of 14.67%.Scanning electron microscopy analysis indicated that the appearance of the microspheres remained largely unchanged post-reaction.Overall,the research findings demonstrated the successful preparation of the anion exchange resin.Characterization and quality assessment confirmed that the ion exchange resin met the required standards.展开更多
How to effectively identify glacial sediments, especially Quaternary moraine, has been in dispute for decades. The traditional methods, e.g., sedimentary and geomorphologic ones, are facing challenge in eastern China ...How to effectively identify glacial sediments, especially Quaternary moraine, has been in dispute for decades. The traditional methods, e.g., sedimentary and geomorphologic ones, are facing challenge in eastern China where controversial moraine deposits are dominatingly distributed. Here, for the first time, we introduce the acoustic emission （AE） stress measurement, a kind of historical stress measurement, to identify Quaternary moraine. The results demonstrate that it can be employed to reconstruct stress information of glaciation remaining in gravels, and may shed light on the identification of Quaternary moraine in eastern China. First, we measured the AE stress of gravels of glacial origin that are underlying the Xidatan Glacier, eastern Kunlun Mountains in western China. Second, we calculated the stress according to the actual thickness of the glacier. The almost identical stress values suggest that the glacial gravels can memorize and preserve the overlying glacier-derived aplomb stress. And then we introduce this new approach to the controversial moraine in Mount Lushan, eastern China. The results indicate that the stress is attributed to the Quaternary glacier, and the muddy gravels in the controversial moraine in Mount Lushan are moraine deposits but not others.展开更多
20130642 Bai Daoyuan (Hunan Institute of Geology Survey , Mineral Exploration and Development of Hunan Province , Changsha 410011 , China); Jia Baohua Potential Genesis of the Trending Changes of Jinning Period and Ca...20130642 Bai Daoyuan (Hunan Institute of Geology Survey , Mineral Exploration and Development of Hunan Province , Changsha 410011 , China); Jia Baohua Potential Genesis of the Trending Changes of Jinning Period and Caledonian Structural Lineamens in Middle-Southern Hunan Province (Journal of Geomechanics , ISSN1006-6616 ,展开更多
基金2023 Nantong Jianghai Talents Project,the Nantong Social Livelihood Science and Technology Plan for 2023the 2022 New Drugs and Platform Enhancement Project of the Yangtze Delta Drug Advanced Research Institute.Additionally,support was provided by the Zhenjiang Science and Technology Project(Grant No.SH2020048)+2 种基金the China Postdoctoral Science Foundation(Grant No.2020M681532)the Jiangsu Planned Projects for Postdoctoral Research Funds(Grant No.2020Z209)the Natural Science Research Projects of Universities in Jiangsu Province(Grant No.20KJD350001).
文摘The aim of this study was to develop a novel pharmaceutical excipient:an anion exchange resin.Initially,polystyrenedivinylbenzene(PS-DVB)microspheres were synthesized via suspension polymerization.Subsequently,these microspheres served as a substrate for chloromethylation using methanol,formaldehyde,and chlorosulfonic acid.By optimizing the reaction conditions,the chloromethylated microspheres were characterized using infrared spectroscopy,scanning electron microscopy,and the Mohr method.Under optimal reaction conditions,the resulting products exhibited uniformity and spherical morphology,with an average particle size of approximately 190μm.The PS-DVB microspheres effectively incorporated chloromethyl groups,as evidenced by a chlorine content of 14.67%.Scanning electron microscopy analysis indicated that the appearance of the microspheres remained largely unchanged post-reaction.Overall,the research findings demonstrated the successful preparation of the anion exchange resin.Characterization and quality assessment confirmed that the ion exchange resin met the required standards.
文摘How to effectively identify glacial sediments, especially Quaternary moraine, has been in dispute for decades. The traditional methods, e.g., sedimentary and geomorphologic ones, are facing challenge in eastern China where controversial moraine deposits are dominatingly distributed. Here, for the first time, we introduce the acoustic emission （AE） stress measurement, a kind of historical stress measurement, to identify Quaternary moraine. The results demonstrate that it can be employed to reconstruct stress information of glaciation remaining in gravels, and may shed light on the identification of Quaternary moraine in eastern China. First, we measured the AE stress of gravels of glacial origin that are underlying the Xidatan Glacier, eastern Kunlun Mountains in western China. Second, we calculated the stress according to the actual thickness of the glacier. The almost identical stress values suggest that the glacial gravels can memorize and preserve the overlying glacier-derived aplomb stress. And then we introduce this new approach to the controversial moraine in Mount Lushan, eastern China. The results indicate that the stress is attributed to the Quaternary glacier, and the muddy gravels in the controversial moraine in Mount Lushan are moraine deposits but not others.
文摘20130642 Bai Daoyuan (Hunan Institute of Geology Survey , Mineral Exploration and Development of Hunan Province , Changsha 410011 , China); Jia Baohua Potential Genesis of the Trending Changes of Jinning Period and Caledonian Structural Lineamens in Middle-Southern Hunan Province (Journal of Geomechanics , ISSN1006-6616 ,
