Mussels are common anchoring organisms that adhere to the surfaces of various substrates with their byssus.The adhesion of mussel to substrates is contingent upon the presence of mussel foot proteins,of which Mytilus ...Mussels are common anchoring organisms that adhere to the surfaces of various substrates with their byssus.The adhesion of mussel to substrates is contingent upon the presence of mussel foot proteins,of which Mytilus edulis foot protein-1(Mefp-1)has been identified as the most abundant protein.It has been found that lipids are involved in the mussel adhesion process and can facilitate Mefp-1adhesion.In this research,the adhesion behavior of Mefp-1 on various substrate surfaces under the effect of typical seawater cations with or without the presence of lipid were investigated using a quartz crystal microbalance with dissipation(QCM-D).Results indicate that the presence of cations Ca^(2+),Mg^(2+),Na^(+),and K^(+)leads to varying degrees of reduction in the adhesion performance of Mefp-1 on different substrates.The degree of this reduction,however,was much alleviated in the presence of palmitic acid,which is involved in the mussel adhesion process.Therefore,the involvement of palmitic acid is advantageous for mussel protein adhesion to the substrate surface in the marine environment.This study illustrated the significant contribution of palmitic acid to mussel adhesion,which can help to better understand biofouling mechanisms and develop biomimetic adhesive materials.展开更多
Different functional polystyrenes were synthesized and the adsorptions of microcystin-LR onto those resins were monitored by quartz crystal microbalance-dissipation. Both adsorption pH and surface properties had a con...Different functional polystyrenes were synthesized and the adsorptions of microcystin-LR onto those resins were monitored by quartz crystal microbalance-dissipation. Both adsorption pH and surface properties had a considerable effect on the adsorption amount, while adsorption temperature was less significant. Ammonium polystyrene would be a better candidate for microcystin-LR adsorption at neutral pH conditions.展开更多
<正>According to the piezoelectric equation and the vibration theory of the quartz crystal,the relations between the vibrating frequency and structural parameters under the thickness-shear-vibration of AT-cut qu...<正>According to the piezoelectric equation and the vibration theory of the quartz crystal,the relations between the vibrating frequency and structural parameters under the thickness-shear-vibration of AT-cut quartz crystal have been studied. The frequency conditions under which quartz crystal resonator formed stationary wave inside the electrode district and the transmission characteristics of wave outside the electrode district have also been discussed.A quartz crystal resonator was developed based on this analysis.The experiment showed that the force-sensing characteristics were independent of the fixation of the crystal edge.The detecting distinguish ability was up to 0.001°,and the short-term frequency stability was up to 1.38×10~ (-10)/min.展开更多
The dynamic characteristics of a quartz crystal resonator（QCR） in thicknessshear modes（TSM） with the upper surface covered by an array of micro-beams immersed in liquid are studied. The liquid is assumed to be inv...The dynamic characteristics of a quartz crystal resonator（QCR） in thicknessshear modes（TSM） with the upper surface covered by an array of micro-beams immersed in liquid are studied. The liquid is assumed to be inviscid and incompressible for simplicity. Dynamic equations of the coupled system are established. The added mass effect of liquid on micro-beams is discussed in detail. Characteristics of frequency shift are clarified for different liquid depths. Modal analysis shows that a drag effect of liquid has resulted in the change of phase of interaction（surface shear force）, thus changing the system resonant frequency. The obtained results are useful in resonator design and applications.展开更多
As humidity is one of the most widely demanded environmental parameters,the precision of its detection is significant.An advanced humidity sensor will improve the validity of the humidity monitoring system.In this stu...As humidity is one of the most widely demanded environmental parameters,the precision of its detection is significant.An advanced humidity sensor will improve the validity of the humidity monitoring system.In this study,a facile chemical layer-by-layer self-assembly(CLS)method was developed for fabricating graphene oxide(GO)/polyethyleneimine(PEI)multilayer films.Owing to the chemical bonding between the PEI and GO,and the intrinsic stickiness of the PEI,layered films with different numbers of layers were successfully prepared using the CLS method and confirmed through ultraviolet-visible(UV-Vis)spectroscopy and the mass loading of quartz crystal microbalance(QCM).Morphological measurements revealed that the roughness and thickness of the films increased exponentially with the number of bilayers.The GO/PEI films were deposited on QCM electrodes using the CLS method to produce the humidity sensors.The humidity measurement results showed a high sensitivity(37.84 Hz/%RH)and rapid response/recovery(<5 s/8 s)of the optimal sensor,which was superior to that of recently developed QCM sensors.展开更多
With introduction of the first-order strain-gradient of surface micro-beams into the energy density function,we developed a two-dimensional dynamic model for a compound quartz crystal resonator（QCR） system,consistin...With introduction of the first-order strain-gradient of surface micro-beams into the energy density function,we developed a two-dimensional dynamic model for a compound quartz crystal resonator（QCR） system,consisting of a QCR and surface micro-beam arrays.The frequency shift that was induced by micro-beams with consideration of strain-gradients is discussed in detail and some useful results are obtained,which have important significance in resonator design and applications.展开更多
We report for the first time a cleavage phenomenon in the resonant peak of a piezoelectric quartz crystal(PQC) in liquid phase.In the presence of a strong longitudinal wave effect,an additional resonant peak appears i...We report for the first time a cleavage phenomenon in the resonant peak of a piezoelectric quartz crystal(PQC) in liquid phase.In the presence of a strong longitudinal wave effect,an additional resonant peak appears in the conductance-frequency curve.With gradually increasing liquid density,the additional peak moves from low to high frequency region then disappears.The frequency of the additional resonant peak is sensitive to the change in liquid density.The frequency shift of the additional peak is linear with the liquid density in a given range.For a 5 MHz PQC with a reflection distance of 16 mm for longitudinal wave,the sensitivity to liquid density is 2.61×10^6 Hz g^-1 cm^3.The overlap between the primary resonant peak and the additional resonant peak causes a decrease in the intensity of the former and an increase in the intensity of the latter.In a combined impedance analysis method,the changes in surface mass loading,density and viscosity of the liquid were monitored simultaneously by a PQC sensor.展开更多
The fast and accurate identification of nerve tracts is critical for successful nerve anastomosis. Taking advantage of differences in acetylcholinesterase content between the spinal ventral and dorsal roots, we develo...The fast and accurate identification of nerve tracts is critical for successful nerve anastomosis. Taking advantage of differences in acetylcholinesterase content between the spinal ventral and dorsal roots, we developed a novel quartz crystal microbalance method to distinguish between these nerves based on acetylcholinesterase antibody reactivity. The acetylcholinesterase antibody was immobilized on the electrode surface of a quartz crystal microbalance and reacted with the acetylcholinesterase in sample solution. The formed antigen and antibody complexes added to the mass of the electrode inducing a change in frequency of the electrode. The spinal ventral and dorsal roots were distinguished by the change in frequency. The ventral and dorsal roots were cut into 1 to 2-mm long segments and then soaked in 250 pL PBS. Acetylcholinesterase antibody was immobilized on the quartz crystal microbalance gold electrode surface. The results revealed that in 10 minutes, both spinal ventral and dorsal roots induced a frequency change; however, the frequency change induced by the ventral roots was notably higher than that induced by the dorsal roots. No change was induced by bovine serum albumin or PBS. These results clearly demonstrate that a quartz crystal microbalance sensor can be used as a rapid, highly sensitive and accurate detection tool for the quick identification of spinal nerve roots intraoperatively.展开更多
The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sen...The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sensor and the working electrode of the electrochemical system.The 6-mecapto-1-hexanol and and the 16-mer oligonucleotide with a mercaptohexyl group at the 5'-phosphate end are utilized to form the SAM on the gold electrode.The frequency response of the QCM during cyclic voltammetry (CV) scanning and cbronoamperometry are recorded together with the electrochemical current.The experimental results indicates that the frequency response is more sensitive to the surface coverage.Therefore,the response of the EQCM reveals more details of the SAM on gold electrode.It is especially useful for analysing the immobilization quality,such as probe orientation and coverage,of the SAM.展开更多
Electrochemical quartz crystal impedance system (EQCIS) which allows in situ dynamic quartz crystal impedance measurement in an electrochemical experiment was developed by combining an HP 4395A Network/Spectrum/Impeda...Electrochemical quartz crystal impedance system (EQCIS) which allows in situ dynamic quartz crystal impedance measurement in an electrochemical experiment was developed by combining an HP 4395A Network/Spectrum/Impedance analyzer with an EG&G M283 potentiostat. Equivalent circuit parameters of crystal resonance change significantly during electrodeposition and dissolution of copper in 0.1 mol/L H2SO4 aqueous solution in a cyclic potential sweep experiment, which is explained with an overall picture of mass loading, solution density and viscosity, etc..展开更多
Calcium phosphate film was prepared by electrochemical deposition technology. Subsequently, the alkaline treatment process of calcium phosphate film in 0.1 mol/L NaOH solution was monitored on real time by the piezoel...Calcium phosphate film was prepared by electrochemical deposition technology. Subsequently, the alkaline treatment process of calcium phosphate film in 0.1 mol/L NaOH solution was monitored on real time by the piezoelectric quartz crystal impedance （PQCI） technique. The variations of morphology and composition for the alkaline treatment products were characterized by scanning electron microscopy （SEM）, Fourier transform infrared （FT-IR） and X-ray diffraction （XRD）, respectively. The dynamic variations of calcium phosphate can be characterized by the change of equivalent circuit parameters. The results show that the forming process of hydroxyapatite （HA） is composed of three stages： （1） acidic calcium phosphate dissolution; （2） phase transformation; and （3） HA formation. Furthermore, the correlative kinetic equations and parameters are obtained by fitting the static capacitance （C8）-time curves.展开更多
We studied the coupled dynamic behavior of a quartz-crystal-resonator （QCR）/micro- beams system in the thickness-shear motions. Through taking into account the couple stress in the dynamic equations of the quartz pl...We studied the coupled dynamic behavior of a quartz-crystal-resonator （QCR）/micro- beams system in the thickness-shear motions. Through taking into account the couple stress in the dynamic equations of the quartz plate, both continuous conditions of shear force and bending moment at the resonator/micro-beams interface are realized. Frequency shift of the compound QCR system induced by micro-beams is studied in detail. The obtained results are useful in device design and frequency-stability analysis of quartz crystal resonators.展开更多
During the fabrication of quartz crystal resonators(QCRs),parallelism error is inevitably generated,which is rarely investigated.In order to reveal the influence of parallelism error on the working performance of QCRs...During the fabrication of quartz crystal resonators(QCRs),parallelism error is inevitably generated,which is rarely investigated.In order to reveal the influence of parallelism error on the working performance of QCRs,the coupled vibration of a non-parallel AT-cut quartz crystal plate with electrodes is systematically studied from the views of theoretical analysis and numerical simulations.The two-dimensional thermal incremental field equations are solved for the free vibration analysis via the coefficient-formed partial differential equation module of the COMSOL Multiphysics software,from which the frequency spectra,frequency–temperature curves,and mode shapes are discussed in detail.Additionally,the piezoelectric module is utilized to obtain the admittance response under different conditions.It is demonstrated that the parallelism error reduces the resonant frequency.Additionally,symmetry broken by the non-parallelism increases the probability of activity dip and is harmful to QCR’s thermal stability.However,if the top and bottom surfaces incline synchronously in the same direction,the influence of parallelism error is tiny.The conclusions achieved are helpful for the QCR design,and the methodology presented can also be applied to other wave devices.展开更多
We study the dynamic behavior of a quartz crystal resonator （QCR） in thickness-shear vibrations with the upper surface covered by an array of micro-beams （MBs） under large deflection. Through taking into account t...We study the dynamic behavior of a quartz crystal resonator （QCR） in thickness-shear vibrations with the upper surface covered by an array of micro-beams （MBs） under large deflection. Through taking into account the continuous conditions of shear force and bending moment at the interface of MBs/resonator, dependences of frequency shift of the compound QCR system versus material parameter and geometrical parameter are illustrated in detail for nonlinear and linear vibrations. It is found that the frequency shift produces a little right （left） translation for increasing elastic modulus （length/radius ratio） of MBs. Moreover, the frequency right （left） translation distance caused by nonlinear deformation becomes more serious in the second-order mode than in the first-order one,展开更多
A dichlorosilane gas and a trichlorosilane gas in ambient hydrogen were evaluated to show their different gas flow motions in a slim vertical cold wall chemical vapor deposition reactor for the Minimal Fab system. Thi...A dichlorosilane gas and a trichlorosilane gas in ambient hydrogen were evaluated to show their different gas flow motions in a slim vertical cold wall chemical vapor deposition reactor for the Minimal Fab system. This evaluation was performed for improving and controlling the film qualities and the productivities, using two quartz crystal microbalances (QCM) installed at the </span><span style="font-family:Verdana;">inlet and exhaust of the chamber by taking into account that the QCM frequency corresponds to the real time changes in the gas properties.</span><span style="font-family:Verdana;"> Typically, the time period approaching from the inlet to the exhaust was shorter for the trichlorosilane gas than that for the dichlorosilane gas. The trichlorosilane gas was shown to move like plug flow, while the dichlorosilane gas seemed to be well mixed in the entire chamber.展开更多
Pd was electrochemically deposited on gold-coated quartz crystals at nanogram-level. The coulombic efficiency and initial nucleation and growth mechanism of potentiostatic Pd deposition were investigated via in situ e...Pd was electrochemically deposited on gold-coated quartz crystals at nanogram-level. The coulombic efficiency and initial nucleation and growth mechanism of potentiostatic Pd deposition were investigated via in situ electrochemical quartz crystal microbalance（EQCM）. The coulombic efficieneies are 84%, 93% and 95% for Pd deposition at 0.3, 0.2 and 0.1 V（vs. SCE）, respectively. The results of chronoamperometric measurements show that the Pd deposition proceeded by an instantaneous nucleation（at 0.3 V） or progressive nucleation（at 0.2 and 0.1 V） in a three-dimensional（3D） growth mode. The catalytic activity of Pd-based electrocatalyst for ethanol oxidation was characterized in an alkaline solution. It was found that the highest mass activity for ethanol oxidation on Pd-based electrocatalyst is 1.8× 10^4 A/（g Pd） deposited at 0.3 V for 5 s.展开更多
An unexpected frequency response for a piezoelectric quartz crystal (PQC) sensor to liquid density and viscosity was reported. For a PQC oscillating in a liquid phase, the frequency shifts (?f ) show a wave-shape re...An unexpected frequency response for a piezoelectric quartz crystal (PQC) sensor to liquid density and viscosity was reported. For a PQC oscillating in a liquid phase, the frequency shifts (?f ) show a wave-shape response to liquid density (ρ) and viscosity (η) in fine structure, if the longitudinal wave effect was not eliminated. This result is different from the well-known linear relationship between of ?f and (ρη)1/2. An oscillating frequency-temperature curve of the sensor was observed and explained.展开更多
The electric admittance of a compound system composed of a thickness-shear mode （TSM） quartz crystal resonator （QCR） and an array of surface viscoelastic micro-beams （MBs） is studied. The governing equations of ...The electric admittance of a compound system composed of a thickness-shear mode （TSM） quartz crystal resonator （QCR） and an array of surface viscoelastic micro-beams （MBs） is studied. The governing equations of the MBs are derived from the Timoshenko-beam theory in consideration of shear deformation. The electrical admittance is described directly in terms of the physical properties of the surface epoxy resin （SU-8） MBs from an electrically forced vibration analysis. It is found that both the inertia effect and the constraint effect of the MBs produce competitive influence on the resonant frequency and admittance of the compound QCR system. By further comparing the numerical results calculated from the Timoshenko-beam model with those from the Euler-beam model, the shear deformation is found to lead to some deviation of an admittance spectrum. The deviations are revealed to be evident around the admittance peak（s） and reach the maximum when a natural frequency of the MBs is identical to the fundamental frequency of the QCR. Besides, a higher order vibration mode of the MBs corresponds to a larger deviation at the resonance.展开更多
The electrochemical quartz crystal impedance system (EQCIS) has been used for the study of a partially immersed Au electrode in 0.2 mol/L NaClO4 aqueous solution. The influences of the immersed area and height of the ...The electrochemical quartz crystal impedance system (EQCIS) has been used for the study of a partially immersed Au electrode in 0.2 mol/L NaClO4 aqueous solution. The influences of the immersed area and height of the electrode on the EQCIS responses were evaluated, showing the highest response sensitivity to liquid loading at the center of the piezoelectric quartz crystal electrode. The increase in the immersed height of the Au electrode at oxygen reduction potentials during potential cycling was measured by this technique.展开更多
The quartz crystal microbalance（QCM） is an important tool that can sense nanogram changes in mass. The hybrid temperature effect on a QCM resonator in aqueous solutions leads to unconvincing detection results. Contr...The quartz crystal microbalance（QCM） is an important tool that can sense nanogram changes in mass. The hybrid temperature effect on a QCM resonator in aqueous solutions leads to unconvincing detection results. Control of the temperature effect is one of the keys when using the QCM for high precision measurements. Based on the Sauerbrey＇s and Kanazawa＇s theories, we proposed a method for enhancing the accuracy of the QCM measurement, which takes into account not only the thermal variations of viscosity and density but also the thermal behavior of the QCM resonator. We presented an improved Sauerbrey equation that can be used to effectively compensate the drift of the QCM resonator. These results will play a significant role when applying the QCM at the room temperature.展开更多
基金Supported by the National Natural Science Foundation of China(No.41776177)the Qingdao Marine Science and Technology Pilot National Laboratory Fund(Nos.2016ASKJ14,QNLM2016ORP0403)。
文摘Mussels are common anchoring organisms that adhere to the surfaces of various substrates with their byssus.The adhesion of mussel to substrates is contingent upon the presence of mussel foot proteins,of which Mytilus edulis foot protein-1(Mefp-1)has been identified as the most abundant protein.It has been found that lipids are involved in the mussel adhesion process and can facilitate Mefp-1adhesion.In this research,the adhesion behavior of Mefp-1 on various substrate surfaces under the effect of typical seawater cations with or without the presence of lipid were investigated using a quartz crystal microbalance with dissipation(QCM-D).Results indicate that the presence of cations Ca^(2+),Mg^(2+),Na^(+),and K^(+)leads to varying degrees of reduction in the adhesion performance of Mefp-1 on different substrates.The degree of this reduction,however,was much alleviated in the presence of palmitic acid,which is involved in the mussel adhesion process.Therefore,the involvement of palmitic acid is advantageous for mussel protein adhesion to the substrate surface in the marine environment.This study illustrated the significant contribution of palmitic acid to mussel adhesion,which can help to better understand biofouling mechanisms and develop biomimetic adhesive materials.
基金This work was supported by the Foundation for scholar of Hefei Normal University （No.2014rcjj03）, the Foundations of Educational Committee of Anhui Province （No.KJ2014A205）, the National Natural Science Foundation of China （No.21101053, No.21101054, No.20934004, No.91127046, and No.20874094）, the One Hundred Talent Project of Chinese Academy of Sciences, and the National Basic Research Program of China （No.2012CB821500 and No.2010CB934500）.
文摘Different functional polystyrenes were synthesized and the adsorptions of microcystin-LR onto those resins were monitored by quartz crystal microbalance-dissipation. Both adsorption pH and surface properties had a considerable effect on the adsorption amount, while adsorption temperature was less significant. Ammonium polystyrene would be a better candidate for microcystin-LR adsorption at neutral pH conditions.
文摘<正>According to the piezoelectric equation and the vibration theory of the quartz crystal,the relations between the vibrating frequency and structural parameters under the thickness-shear-vibration of AT-cut quartz crystal have been studied. The frequency conditions under which quartz crystal resonator formed stationary wave inside the electrode district and the transmission characteristics of wave outside the electrode district have also been discussed.A quartz crystal resonator was developed based on this analysis.The experiment showed that the force-sensing characteristics were independent of the fixation of the crystal edge.The detecting distinguish ability was up to 0.001°,and the short-term frequency stability was up to 1.38×10~ (-10)/min.
基金Project supported by the National Natural Science Foundation of China(Nos.11272127 and51425006)the Research Fund for the Doctoral Program of Higher Education of China(No.20130142110022)the Grant from the Impact and Safety of Coastal Engineering Initiative Program of Zhejiang Provincial Government at Ningbo University(No.zj1213)
文摘The dynamic characteristics of a quartz crystal resonator（QCR） in thicknessshear modes（TSM） with the upper surface covered by an array of micro-beams immersed in liquid are studied. The liquid is assumed to be inviscid and incompressible for simplicity. Dynamic equations of the coupled system are established. The added mass effect of liquid on micro-beams is discussed in detail. Characteristics of frequency shift are clarified for different liquid depths. Modal analysis shows that a drag effect of liquid has resulted in the change of phase of interaction（surface shear force）, thus changing the system resonant frequency. The obtained results are useful in resonator design and applications.
基金financially supported by the National Natural Science Foundation of China(No.U19A2070)the National Science Funds for Excellent Young Scholars of China(No.61822106)the National Science Funds for Creative Research Groups of China(No.61421002)。
文摘As humidity is one of the most widely demanded environmental parameters,the precision of its detection is significant.An advanced humidity sensor will improve the validity of the humidity monitoring system.In this study,a facile chemical layer-by-layer self-assembly(CLS)method was developed for fabricating graphene oxide(GO)/polyethyleneimine(PEI)multilayer films.Owing to the chemical bonding between the PEI and GO,and the intrinsic stickiness of the PEI,layered films with different numbers of layers were successfully prepared using the CLS method and confirmed through ultraviolet-visible(UV-Vis)spectroscopy and the mass loading of quartz crystal microbalance(QCM).Morphological measurements revealed that the roughness and thickness of the films increased exponentially with the number of bilayers.The GO/PEI films were deposited on QCM electrodes using the CLS method to produce the humidity sensors.The humidity measurement results showed a high sensitivity(37.84 Hz/%RH)and rapid response/recovery(<5 s/8 s)of the optimal sensor,which was superior to that of recently developed QCM sensors.
基金supported by the National Science Foundation of China(Grants 11272127 and 51435006)Research Fund for the Doctoral Program of Higher Education of China(Grant 20130142110022)the Grant from the Impact and Safety of Coastal Engineering Initiative Program of Zhejiang Provincial Government at Ningbo University(Grant zj1213)
文摘With introduction of the first-order strain-gradient of surface micro-beams into the energy density function,we developed a two-dimensional dynamic model for a compound quartz crystal resonator（QCR） system,consisting of a QCR and surface micro-beam arrays.The frequency shift that was induced by micro-beams with consideration of strain-gradients is discussed in detail and some useful results are obtained,which have important significance in resonator design and applications.
基金supported by the National Natural Science Foundation of China(Nos.20775045,20975063)open foundation of the State Key Laboratory of Chemo/Biosensing and Chemometrics,Hunan University(No.2008012)
文摘We report for the first time a cleavage phenomenon in the resonant peak of a piezoelectric quartz crystal(PQC) in liquid phase.In the presence of a strong longitudinal wave effect,an additional resonant peak appears in the conductance-frequency curve.With gradually increasing liquid density,the additional peak moves from low to high frequency region then disappears.The frequency of the additional resonant peak is sensitive to the change in liquid density.The frequency shift of the additional peak is linear with the liquid density in a given range.For a 5 MHz PQC with a reflection distance of 16 mm for longitudinal wave,the sensitivity to liquid density is 2.61×10^6 Hz g^-1 cm^3.The overlap between the primary resonant peak and the additional resonant peak causes a decrease in the intensity of the former and an increase in the intensity of the latter.In a combined impedance analysis method,the changes in surface mass loading,density and viscosity of the liquid were monitored simultaneously by a PQC sensor.
基金supported by the National Natural Science Foundation of China,No. 30973058,81171694Jiangsu Province Natural Science Foundation,No. BE2010743+2 种基金Jiangsu Graduate Student Innovation Project,No.CXZZ11_0721the Program for Development of Innovative Research Team in the First Affiliated Hospital of Nanjing Medical University,No. IRT-015a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘The fast and accurate identification of nerve tracts is critical for successful nerve anastomosis. Taking advantage of differences in acetylcholinesterase content between the spinal ventral and dorsal roots, we developed a novel quartz crystal microbalance method to distinguish between these nerves based on acetylcholinesterase antibody reactivity. The acetylcholinesterase antibody was immobilized on the electrode surface of a quartz crystal microbalance and reacted with the acetylcholinesterase in sample solution. The formed antigen and antibody complexes added to the mass of the electrode inducing a change in frequency of the electrode. The spinal ventral and dorsal roots were distinguished by the change in frequency. The ventral and dorsal roots were cut into 1 to 2-mm long segments and then soaked in 250 pL PBS. Acetylcholinesterase antibody was immobilized on the quartz crystal microbalance gold electrode surface. The results revealed that in 10 minutes, both spinal ventral and dorsal roots induced a frequency change; however, the frequency change induced by the ventral roots was notably higher than that induced by the dorsal roots. No change was induced by bovine serum albumin or PBS. These results clearly demonstrate that a quartz crystal microbalance sensor can be used as a rapid, highly sensitive and accurate detection tool for the quick identification of spinal nerve roots intraoperatively.
文摘The electrochemical quartz crystal microbalance (EQCM) is used to investigate the characteristics of the thiolated self-assembled monolayer(SAM) on gold surface.A 5MHz QCM element serves as both the mass-sensitive sensor and the working electrode of the electrochemical system.The 6-mecapto-1-hexanol and and the 16-mer oligonucleotide with a mercaptohexyl group at the 5'-phosphate end are utilized to form the SAM on the gold electrode.The frequency response of the QCM during cyclic voltammetry (CV) scanning and cbronoamperometry are recorded together with the electrochemical current.The experimental results indicates that the frequency response is more sensitive to the surface coverage.Therefore,the response of the EQCM reveals more details of the SAM on gold electrode.It is especially useful for analysing the immobilization quality,such as probe orientation and coverage,of the SAM.
文摘Electrochemical quartz crystal impedance system (EQCIS) which allows in situ dynamic quartz crystal impedance measurement in an electrochemical experiment was developed by combining an HP 4395A Network/Spectrum/Impedance analyzer with an EG&G M283 potentiostat. Equivalent circuit parameters of crystal resonance change significantly during electrodeposition and dissolution of copper in 0.1 mol/L H2SO4 aqueous solution in a cyclic potential sweep experiment, which is explained with an overall picture of mass loading, solution density and viscosity, etc..
基金Project(2005CB623901) supported by the Major State Basic Research and Development Program of China
文摘Calcium phosphate film was prepared by electrochemical deposition technology. Subsequently, the alkaline treatment process of calcium phosphate film in 0.1 mol/L NaOH solution was monitored on real time by the piezoelectric quartz crystal impedance （PQCI） technique. The variations of morphology and composition for the alkaline treatment products were characterized by scanning electron microscopy （SEM）, Fourier transform infrared （FT-IR） and X-ray diffraction （XRD）, respectively. The dynamic variations of calcium phosphate can be characterized by the change of equivalent circuit parameters. The results show that the forming process of hydroxyapatite （HA） is composed of three stages： （1） acidic calcium phosphate dissolution; （2） phase transformation; and （3） HA formation. Furthermore, the correlative kinetic equations and parameters are obtained by fitting the static capacitance （C8）-time curves.
基金supported by the National Nature Science Foundation of China(Nos.11272127 and 51435006)by Research Fund for the Doctoral Program of Higher Education of China(No.20130142110022)by Grant from the Impact and Safety of Coastal Engineering Initiative Program of Zhejiang Provincial Government at Ningbo University(No.zj1213)
文摘We studied the coupled dynamic behavior of a quartz-crystal-resonator （QCR）/micro- beams system in the thickness-shear motions. Through taking into account the couple stress in the dynamic equations of the quartz plate, both continuous conditions of shear force and bending moment at the resonator/micro-beams interface are realized. Frequency shift of the compound QCR system induced by micro-beams is studied in detail. The obtained results are useful in device design and frequency-stability analysis of quartz crystal resonators.
基金supported by the National Natural Science Foundation of China(12061131013,11972276,12172171 and 12102183)the Fundamental Research Funds for the Central Universities(NE2020002 andNS2022011)+5 种基金JiangsuHigh-Level Innovative and Entrepreneurial Talents Introduction Plan(Shuangchuang Doctor Program,JSSCBS20210166)the National Natural Science Foundation of Jiangsu Province(BK20211176)the State Key Laboratory of Mechanics and Control of Mechanical Structures at NUAA(No.MCMS-I-0522G01)Local Science andTechnologyDevelopment Fund ProjectsGuided by the CentralGovernment(2021Szvup061)the Opening Projects from the Key Laboratory of Impact and Safety Engineering of Ningbo University(CJ202104)a project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
文摘During the fabrication of quartz crystal resonators(QCRs),parallelism error is inevitably generated,which is rarely investigated.In order to reveal the influence of parallelism error on the working performance of QCRs,the coupled vibration of a non-parallel AT-cut quartz crystal plate with electrodes is systematically studied from the views of theoretical analysis and numerical simulations.The two-dimensional thermal incremental field equations are solved for the free vibration analysis via the coefficient-formed partial differential equation module of the COMSOL Multiphysics software,from which the frequency spectra,frequency–temperature curves,and mode shapes are discussed in detail.Additionally,the piezoelectric module is utilized to obtain the admittance response under different conditions.It is demonstrated that the parallelism error reduces the resonant frequency.Additionally,symmetry broken by the non-parallelism increases the probability of activity dip and is harmful to QCR’s thermal stability.However,if the top and bottom surfaces incline synchronously in the same direction,the influence of parallelism error is tiny.The conclusions achieved are helpful for the QCR design,and the methodology presented can also be applied to other wave devices.
基金supported by the National Natural Science Foundation of China(11272127 and 51435006)the Research Fund for the Doctoral Program of Higher Education of China(20130142110022)
文摘We study the dynamic behavior of a quartz crystal resonator （QCR） in thickness-shear vibrations with the upper surface covered by an array of micro-beams （MBs） under large deflection. Through taking into account the continuous conditions of shear force and bending moment at the interface of MBs/resonator, dependences of frequency shift of the compound QCR system versus material parameter and geometrical parameter are illustrated in detail for nonlinear and linear vibrations. It is found that the frequency shift produces a little right （left） translation for increasing elastic modulus （length/radius ratio） of MBs. Moreover, the frequency right （left） translation distance caused by nonlinear deformation becomes more serious in the second-order mode than in the first-order one,
文摘A dichlorosilane gas and a trichlorosilane gas in ambient hydrogen were evaluated to show their different gas flow motions in a slim vertical cold wall chemical vapor deposition reactor for the Minimal Fab system. This evaluation was performed for improving and controlling the film qualities and the productivities, using two quartz crystal microbalances (QCM) installed at the </span><span style="font-family:Verdana;">inlet and exhaust of the chamber by taking into account that the QCM frequency corresponds to the real time changes in the gas properties.</span><span style="font-family:Verdana;"> Typically, the time period approaching from the inlet to the exhaust was shorter for the trichlorosilane gas than that for the dichlorosilane gas. The trichlorosilane gas was shown to move like plug flow, while the dichlorosilane gas seemed to be well mixed in the entire chamber.
基金Supported by the Guangdong Science and Technology Key Projects, China(Nos.2007A010700001, 2007B090400032)Guangzhou Science and Technology Key Projects, China(Nos.2007Z1-D0051, SKT[2007]17-11) the Scientific Research Foundation for Young Teachers of the Sun Yat-Sen University, China(No.2006-31000-1131214)
文摘Pd was electrochemically deposited on gold-coated quartz crystals at nanogram-level. The coulombic efficiency and initial nucleation and growth mechanism of potentiostatic Pd deposition were investigated via in situ electrochemical quartz crystal microbalance（EQCM）. The coulombic efficieneies are 84%, 93% and 95% for Pd deposition at 0.3, 0.2 and 0.1 V（vs. SCE）, respectively. The results of chronoamperometric measurements show that the Pd deposition proceeded by an instantaneous nucleation（at 0.3 V） or progressive nucleation（at 0.2 and 0.1 V） in a three-dimensional（3D） growth mode. The catalytic activity of Pd-based electrocatalyst for ethanol oxidation was characterized in an alkaline solution. It was found that the highest mass activity for ethanol oxidation on Pd-based electrocatalyst is 1.8× 10^4 A/（g Pd） deposited at 0.3 V for 5 s.
基金supported by the National Natural Science Foundation of China(No.20275021)
文摘An unexpected frequency response for a piezoelectric quartz crystal (PQC) sensor to liquid density and viscosity was reported. For a PQC oscillating in a liquid phase, the frequency shifts (?f ) show a wave-shape response to liquid density (ρ) and viscosity (η) in fine structure, if the longitudinal wave effect was not eliminated. This result is different from the well-known linear relationship between of ?f and (ρη)1/2. An oscillating frequency-temperature curve of the sensor was observed and explained.
基金Project supported by the National Natural Science Foundation of China(Nos.11272127 and51435006)the Research Fund for the Doctoral Program of Higher Education of China(No.20130142110022)
文摘The electric admittance of a compound system composed of a thickness-shear mode （TSM） quartz crystal resonator （QCR） and an array of surface viscoelastic micro-beams （MBs） is studied. The governing equations of the MBs are derived from the Timoshenko-beam theory in consideration of shear deformation. The electrical admittance is described directly in terms of the physical properties of the surface epoxy resin （SU-8） MBs from an electrically forced vibration analysis. It is found that both the inertia effect and the constraint effect of the MBs produce competitive influence on the resonant frequency and admittance of the compound QCR system. By further comparing the numerical results calculated from the Timoshenko-beam model with those from the Euler-beam model, the shear deformation is found to lead to some deviation of an admittance spectrum. The deviations are revealed to be evident around the admittance peak（s） and reach the maximum when a natural frequency of the MBs is identical to the fundamental frequency of the QCR. Besides, a higher order vibration mode of the MBs corresponds to a larger deviation at the resonance.
基金This work was supported by the National Natural Science Foundation of China the Science and Technology Foundation of Hunan P
文摘The electrochemical quartz crystal impedance system (EQCIS) has been used for the study of a partially immersed Au electrode in 0.2 mol/L NaClO4 aqueous solution. The influences of the immersed area and height of the electrode on the EQCIS responses were evaluated, showing the highest response sensitivity to liquid loading at the center of the piezoelectric quartz crystal electrode. The increase in the immersed height of the Au electrode at oxygen reduction potentials during potential cycling was measured by this technique.
基金supported by the National Natural Science Foundation of China(Grant No.61672094)
文摘The quartz crystal microbalance（QCM） is an important tool that can sense nanogram changes in mass. The hybrid temperature effect on a QCM resonator in aqueous solutions leads to unconvincing detection results. Control of the temperature effect is one of the keys when using the QCM for high precision measurements. Based on the Sauerbrey＇s and Kanazawa＇s theories, we proposed a method for enhancing the accuracy of the QCM measurement, which takes into account not only the thermal variations of viscosity and density but also the thermal behavior of the QCM resonator. We presented an improved Sauerbrey equation that can be used to effectively compensate the drift of the QCM resonator. These results will play a significant role when applying the QCM at the room temperature.
