The composite quantile regression should provide estimation efficiency gain over a single quantile regression. In this paper, we extend composite quantile regression to nonparametric model with random censored data. T...The composite quantile regression should provide estimation efficiency gain over a single quantile regression. In this paper, we extend composite quantile regression to nonparametric model with random censored data. The asymptotic normality of the proposed estimator is established. The proposed methods are applied to the lung cancer data. Extensive simulations are reported, showing that the proposed method works well in practical settings.展开更多
In clinical research,subgroup analysis can help identify patient groups that respond better or worse to specific treatments,improve therapeutic effect and safety,and is of great significance in precision medicine.This...In clinical research,subgroup analysis can help identify patient groups that respond better or worse to specific treatments,improve therapeutic effect and safety,and is of great significance in precision medicine.This article considers subgroup analysis methods for longitudinal data containing multiple covariates and biomarkers.We divide subgroups based on whether a linear combination of these biomarkers exceeds a predetermined threshold,and assess the heterogeneity of treatment effects across subgroups using the interaction between subgroups and exposure variables.Quantile regression is used to better characterize the global distribution of the response variable and sparsity penalties are imposed to achieve variable selection of covariates and biomarkers.The effectiveness of our proposed methodology for both variable selection and parameter estimation is verified through random simulations.Finally,we demonstrate the application of this method by analyzing data from the PA.3 trial,further illustrating the practicality of the method proposed in this paper.展开更多
This paper considers quantile regression analysis based on semi-competing risks data in which a non-terminal event may be dependently censored by a terminal event. The major interest is the covariate effects on the qu...This paper considers quantile regression analysis based on semi-competing risks data in which a non-terminal event may be dependently censored by a terminal event. The major interest is the covariate effects on the quantile of the non-terminal event time. Dependent censoring is handled by assuming that the joint distribution of the two event times follows a parametric copula model with unspecified marginal distributions. The technique of inverse probability weighting (IPW) is adopted to adjust for the selection bias. Large-sample properties of the proposed estimator are derived and a model diagnostic procedure is developed to check the adequacy of the model assumption. Simulation results show that the proposed estimator performs well. For illustrative purposes, our method is applied to analyze the bone marrow transplant data in [1].展开更多
In this study, we adopt kernel density estimation, spatial autocorrelation, spatial Markov chain, and panel quantile regression methods to analyze spatial spillover effects and driving factors of carbon emission inten...In this study, we adopt kernel density estimation, spatial autocorrelation, spatial Markov chain, and panel quantile regression methods to analyze spatial spillover effects and driving factors of carbon emission intensity in 283 Chinese cities from 1992 to 2013. The following results were obtained.(1) Nuclear density estimation shows that the overall average carbon intensity of cities in China has decreased, with differences gradually narrowing.(2) The spatial autocorrelation Moran's I index indicates significant spatial agglomeration of carbon emission intensity is gradually increasing; however, differences between regions have remained stable.(3) Spatial Markov chain analysis shows a Matthew effect in China's urban carbon emission intensity. In addition, low-intensity and high-intensity cities characteristically maintain their initial state during the transition period. Furthermore, there is a clear "Spatial Spillover" effect in urban carbon emission intensity and there is heterogeneity in the spillover effect in different regional contexts; that is, if a city is near a city with low carbon emission intensity, the carbon emission intensity of the first city has a higher probability of upward transfer, and vice versa.(4) Panel quantile results indicate that in cities with low carbon emission intensity, economic growth, technological progress, and appropriate population density play an important role in reducing emissions. In addition, foreign investment intensity and traffic emissions are the main factors that increase carbon emission intensity. In cities with high carbon intensity, population density is an important emission reduction factor, and technological progress has no significant effect. In contrast, industrial emissions, extensive capital investment, and urban land expansion are the main factors driving the increase in carbon intensity.展开更多
Panel count data are frequently encountered when study subjects are under discrete observations.However,limited literature has been found on variable selection for panel count data.In this paper,without considering th...Panel count data are frequently encountered when study subjects are under discrete observations.However,limited literature has been found on variable selection for panel count data.In this paper,without considering the model assumption of observation process,a more general semiparametric transformation model for panel count data with informative observation process is developed.A penalized estimation procedure based on the quantile regression function is proposed for variable selection and parameter estimation simultaneously.The consistency and oracle properties of the estimators are established under some mild conditions.Some simulations and an application are reported to evaluate the proposed approach.展开更多
A comprehensive evaluation index system is constructed,and the entropy weight TOPSIS method isused to measure the optimization level of the digital economy and tourism industry structure of 30 provinces inChina from 2...A comprehensive evaluation index system is constructed,and the entropy weight TOPSIS method isused to measure the optimization level of the digital economy and tourism industry structure of 30 provinces inChina from 2012 to 2021.Moreover,models such as quantile regression and panel threshold are used to explorethe influence of the digital economy(DIG)on the optimization of the tourism industry structure(TIS)as well as itstransmission mechanism.The study reveals that DIG significantly promotes TIS,which remains valid after endogeneity and robustness tests;the impact of DIG on TIS exhibited a“U-shape”effect that first decreases and thenincreases,and its highest significance is at the 90%quartile level.Threshold model tests revealed a nonlinearthreshold effect with DIG and tourism total factor productivity(TTFP)as a single threshold and tourism technological progress index(TECH)as a double threshold,and the second threshold has the largest effect of 0.163.Mechanism analysis found that the mediating impact of the DIG on the TIS was mediated by increasing the TTFP,and the TECH accounted for the highest proportion of 12.15%.Regional analysis revealed that the role of DIG onthe TIS is Central>East>West>Northeast,and the empowering effect is more significant in the high digital economylevel area and the high tourism industry structure optimization area.展开更多
文摘The composite quantile regression should provide estimation efficiency gain over a single quantile regression. In this paper, we extend composite quantile regression to nonparametric model with random censored data. The asymptotic normality of the proposed estimator is established. The proposed methods are applied to the lung cancer data. Extensive simulations are reported, showing that the proposed method works well in practical settings.
基金Supported by the Natural Science Foundation of Fujian Province(2022J011177,2024J01903)the Key Project of Fujian Provincial Education Department(JZ230054)。
文摘In clinical research,subgroup analysis can help identify patient groups that respond better or worse to specific treatments,improve therapeutic effect and safety,and is of great significance in precision medicine.This article considers subgroup analysis methods for longitudinal data containing multiple covariates and biomarkers.We divide subgroups based on whether a linear combination of these biomarkers exceeds a predetermined threshold,and assess the heterogeneity of treatment effects across subgroups using the interaction between subgroups and exposure variables.Quantile regression is used to better characterize the global distribution of the response variable and sparsity penalties are imposed to achieve variable selection of covariates and biomarkers.The effectiveness of our proposed methodology for both variable selection and parameter estimation is verified through random simulations.Finally,we demonstrate the application of this method by analyzing data from the PA.3 trial,further illustrating the practicality of the method proposed in this paper.
文摘This paper considers quantile regression analysis based on semi-competing risks data in which a non-terminal event may be dependently censored by a terminal event. The major interest is the covariate effects on the quantile of the non-terminal event time. Dependent censoring is handled by assuming that the joint distribution of the two event times follows a parametric copula model with unspecified marginal distributions. The technique of inverse probability weighting (IPW) is adopted to adjust for the selection bias. Large-sample properties of the proposed estimator are derived and a model diagnostic procedure is developed to check the adequacy of the model assumption. Simulation results show that the proposed estimator performs well. For illustrative purposes, our method is applied to analyze the bone marrow transplant data in [1].
基金National Natural Science Foundation of China,No.41601151Natural Science Foundation of Guangdong Province,No.2016A030310149Pearl River S&T Nova Program of Guangzhou(201806010187)
文摘In this study, we adopt kernel density estimation, spatial autocorrelation, spatial Markov chain, and panel quantile regression methods to analyze spatial spillover effects and driving factors of carbon emission intensity in 283 Chinese cities from 1992 to 2013. The following results were obtained.(1) Nuclear density estimation shows that the overall average carbon intensity of cities in China has decreased, with differences gradually narrowing.(2) The spatial autocorrelation Moran's I index indicates significant spatial agglomeration of carbon emission intensity is gradually increasing; however, differences between regions have remained stable.(3) Spatial Markov chain analysis shows a Matthew effect in China's urban carbon emission intensity. In addition, low-intensity and high-intensity cities characteristically maintain their initial state during the transition period. Furthermore, there is a clear "Spatial Spillover" effect in urban carbon emission intensity and there is heterogeneity in the spillover effect in different regional contexts; that is, if a city is near a city with low carbon emission intensity, the carbon emission intensity of the first city has a higher probability of upward transfer, and vice versa.(4) Panel quantile results indicate that in cities with low carbon emission intensity, economic growth, technological progress, and appropriate population density play an important role in reducing emissions. In addition, foreign investment intensity and traffic emissions are the main factors that increase carbon emission intensity. In cities with high carbon intensity, population density is an important emission reduction factor, and technological progress has no significant effect. In contrast, industrial emissions, extensive capital investment, and urban land expansion are the main factors driving the increase in carbon intensity.
基金partially supported by the National Natural Science Foundation of China under Grant No.12001485the National Bureau of Statistics of China under Grant No.2020LY073the First Class Discipline of Zhejiang-A(Zhejiang University of Finance and Economics-Statistics)under Grant No.Z0111119010/024。
文摘Panel count data are frequently encountered when study subjects are under discrete observations.However,limited literature has been found on variable selection for panel count data.In this paper,without considering the model assumption of observation process,a more general semiparametric transformation model for panel count data with informative observation process is developed.A penalized estimation procedure based on the quantile regression function is proposed for variable selection and parameter estimation simultaneously.The consistency and oracle properties of the estimators are established under some mild conditions.Some simulations and an application are reported to evaluate the proposed approach.
基金The National Natural Science Foundation of China(42261042)The Hunan Provincial Natural Science Foundation(2024JJ7410)The Hunan Provincial Graduate Student Research and Innovation Program(CX20221095)。
文摘A comprehensive evaluation index system is constructed,and the entropy weight TOPSIS method isused to measure the optimization level of the digital economy and tourism industry structure of 30 provinces inChina from 2012 to 2021.Moreover,models such as quantile regression and panel threshold are used to explorethe influence of the digital economy(DIG)on the optimization of the tourism industry structure(TIS)as well as itstransmission mechanism.The study reveals that DIG significantly promotes TIS,which remains valid after endogeneity and robustness tests;the impact of DIG on TIS exhibited a“U-shape”effect that first decreases and thenincreases,and its highest significance is at the 90%quartile level.Threshold model tests revealed a nonlinearthreshold effect with DIG and tourism total factor productivity(TTFP)as a single threshold and tourism technological progress index(TECH)as a double threshold,and the second threshold has the largest effect of 0.163.Mechanism analysis found that the mediating impact of the DIG on the TIS was mediated by increasing the TTFP,and the TECH accounted for the highest proportion of 12.15%.Regional analysis revealed that the role of DIG onthe TIS is Central>East>West>Northeast,and the empowering effect is more significant in the high digital economylevel area and the high tourism industry structure optimization area.