目的:建立中药材中8种真菌毒素的超高效液相色谱—串联质谱检测方法。方法:样品经粉碎过筛后用乙腈水溶液提取,经多功能净化柱Pribo Fast 100进行净化,采用XTerra MS C18色谱柱进行分离,以20mmol/L乙酸铵溶液和乙腈梯度洗脱,利用超高效...目的:建立中药材中8种真菌毒素的超高效液相色谱—串联质谱检测方法。方法:样品经粉碎过筛后用乙腈水溶液提取,经多功能净化柱Pribo Fast 100进行净化,采用XTerra MS C18色谱柱进行分离,以20mmol/L乙酸铵溶液和乙腈梯度洗脱,利用超高效液相色谱—串联质谱进行分析。结果:8种真菌毒素在测定浓度范围内线性关系良好,各组分相关系数R2> 0. 998,加标回收率范围72. 1%~92. 8%,方法精密度范围6. 3%~12. 2%,测定各组分真菌毒素定量限范围1. 2~2. 0μg/kg。结论:方法前处理过程简洁、灵敏度高、重现性好,适用于中药材中8种真菌毒素的测定。展开更多
We consider a class of mathematical programs governed by parameterized quasi-variational inequalities(QVI).The necessary optimality conditions for the optimization problem with QVI constraints are reformulated as a sy...We consider a class of mathematical programs governed by parameterized quasi-variational inequalities(QVI).The necessary optimality conditions for the optimization problem with QVI constraints are reformulated as a system of nonsmooth equations under the linear independence constraint qualification and the strict slackness condition.A set of second order sufficient conditions for the mathematical program with parameterized QVI constraints are proposed,which are demonstrated to be sufficient for the second order growth condition.The strongly BD-regularity for the nonsmooth system of equations at a solution point is demonstrated under the second order sufficient conditions.The smoothing Newton method in Qi-Sun-Zhou [2000] is employed to solve this nonsmooth system and the quadratic convergence is guaranteed by the strongly BD-regularity.Numerical experiments are reported to show that the smoothing Newton method is very effective for solving this class of optimization problems.展开更多
基金supported by National Natural Science Foundation of China (Grant No.11071029)the Fundamental Research Funds for the Central Universities
文摘We consider a class of mathematical programs governed by parameterized quasi-variational inequalities(QVI).The necessary optimality conditions for the optimization problem with QVI constraints are reformulated as a system of nonsmooth equations under the linear independence constraint qualification and the strict slackness condition.A set of second order sufficient conditions for the mathematical program with parameterized QVI constraints are proposed,which are demonstrated to be sufficient for the second order growth condition.The strongly BD-regularity for the nonsmooth system of equations at a solution point is demonstrated under the second order sufficient conditions.The smoothing Newton method in Qi-Sun-Zhou [2000] is employed to solve this nonsmooth system and the quadratic convergence is guaranteed by the strongly BD-regularity.Numerical experiments are reported to show that the smoothing Newton method is very effective for solving this class of optimization problems.
