Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions to...Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?展开更多
Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CASTopic of the Special Issue What are the top questions tow...Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CASTopic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?展开更多
Determining clinical questions is fundamental to the development of clinical practice guidelines(CPGs),which bridges the initial phases and the final recommendations.It is essential for evidence retrieval and the form...Determining clinical questions is fundamental to the development of clinical practice guidelines(CPGs),which bridges the initial phases and the final recommendations.It is essential for evidence retrieval and the formulation of recommendations.The scientific rigor and precision in determination of clinical questions directly influence the future implementation and applicability of guidelines.In 2020,the World Federation of Acupuncture-Moxibustion Societies initiated the project of clinical practice guideline on acupuncture and moxibustion for adult major depressive disorder(mild-moderate degree)to address clinical and medical decision-making issues in acupuncture treatment for adult mild to moderate major depressive disorder.This CPG provides systematic recommendations based on clinical evidence,patient values,and other factors,aiding decision-makers,clinicians,and patients in selecting appropriate interventions.This paper discusses and analyzes the determination process of clinical questions,and the related issues during the development of this guideline,aiming to provide a reference for determining clinical questions and developing CPGs in the field of acupuncture and exploring more scientific tools and methods for determining clinical questions in future CPGs.展开更多
Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions to...Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?展开更多
In literature,differences in the description of female and male characters have been noticeable for a long time.In this study,the novel Jane Eyre is uses as a material to investigate whether there are in fact any sign...In literature,differences in the description of female and male characters have been noticeable for a long time.In this study,the novel Jane Eyre is uses as a material to investigate whether there are in fact any significant differences in the questions Mr.Rochester and Jane use and how the questions function to portray these two main characters.展开更多
Obesity is recognized as the second highest risk factor for cancer. The pathogenic mechanisms underlying tobaccorelated cancers are well characterized and efective programs have led to a decline in smoking and related...Obesity is recognized as the second highest risk factor for cancer. The pathogenic mechanisms underlying tobaccorelated cancers are well characterized and efective programs have led to a decline in smoking and related cancers, but there is a global epidemic of obesity without a clear understanding of how obesity causes cancer. Obesity is heterogeneous, and approximately 25% of obese individuals remain healthy(metabolically healthy obese, MHO), so which fat deposition(subcutaneous versus visceral, adipose versus ectopic) is "malignant"? What is the mechanism of carcinogenesis? Is it by metabolic dysregulation or chronic inflammation? Through which chemokines/genes/signaling pathways does adipose tissue influence carcinogenesis? Can selective inhibition of these pathways uncouple obesity from cancers? Do all obesity related cancers(ORCs) share a molecular signature? Are there common(overlapping) genetic loci that make individuals susceptible to obesity, metabolic syndrome, and cancers? Can we identify precursor lesions of ORCs and will early intervention of high risk individuals alter the natural history? It appears unlikely that the obesity epidemic will be controlled anytime soon; answers to these questions will help to reduce the adverse efect of obesity on human condition.展开更多
As the world’s largest developing country,the ability of China’s agricultural resource utilization to effectively support the current and future food security goals has been affected by a variety of factors(e.g.,tra...As the world’s largest developing country,the ability of China’s agricultural resource utilization to effectively support the current and future food security goals has been affected by a variety of factors(e.g.,transformed supply channels,tightening international situation and frequent emergencies)in recent years and has attracted extensive attention from the academic community subject to multiple factors.This study uses literature review,statistical analysis,and spatial analysis methods to systematically explore China’s food security situation in the context of farmland resource constraints.It is found that the demand-side pressures such as demographic changes,social class differentiation,and dietary structure adjustments derived from economic growth and rapid urbanization have placed extremely high expectations on food supply.However,the quantitative restrictions,utilization ways,and health risks of farmland resources on the supply side constitute a huge hidden concern that affects the stability of food production.Although China’s farmland protection system is undergoing a transition from focusing on quantity management to sustainable use,the matching and coordinating demand pressure and supply capacity for food security is unbalanced.Therefore,facing uncertain future development scenarios,policymakers should focus on building a resilient space for China’s farmland protection to withstand the interference of major emergencies.The existing farmland protection space policy can be integrated by establishing a national farmland strategic reserve system(based on resilient space),and further development of targeted use control measures for zoning,grading,and classification will help realize sustainable China’s farmland resources use.展开更多
With the emergence of large-scale knowledge base,how to use triple information to generate natural questions is a key technology in question answering systems.The traditional way of generating questions require a lot ...With the emergence of large-scale knowledge base,how to use triple information to generate natural questions is a key technology in question answering systems.The traditional way of generating questions require a lot of manual intervention and produce lots of noise.To solve these problems,we propose a joint model based on semi-automated model and End-to-End neural network to automatically generate questions.The semi-automated model can generate question templates and real questions combining the knowledge base and center graph.The End-to-End neural network directly sends the knowledge base and real questions to BiLSTM network.Meanwhile,the attention mechanism is utilized in the decoding layer,which makes the triples and generated questions more relevant.Finally,the experimental results on SimpleQuestions demonstrate the effectiveness of the proposed approach.展开更多
Fatigue is best defined as difficulty in initiating or sustaining voluntary activities, and is thought to be accompanied by deterioration of performance. Fatigue can be caused by many factors such as physical and ment...Fatigue is best defined as difficulty in initiating or sustaining voluntary activities, and is thought to be accompanied by deterioration of performance. Fatigue can be caused by many factors such as physical and mental stress, disturbance in the circadian rhythm, and various diseases. For example, following the flu or other types of infections, everyone has experienced a sense of fatigue that can last for days or weeks. The fatigue sensation is thought to be one of the signals for the body to suppress physical activity in order to regain health. The mechanism of induction of the fatigue sensation following viral infection has not been well understood. Although fatigue was once thought to be caused by fever, our recent study with an animal model of viral infection demonstrated that the fatigue sensation is caused not by fever, but rather,展开更多
The frequent occurrence of echo questions in people's daily conversation has not arouse enough interest in linguists yet; meanwhile, different scholars hold different views when it comes to such questions as how f...The frequent occurrence of echo questions in people's daily conversation has not arouse enough interest in linguists yet; meanwhile, different scholars hold different views when it comes to such questions as how far the boundary of echo questions should extend, how they should be classified, etc. The following paper gives the echo question a new definition and classification. It hopes to provide a more persuasive reference of future researchers.展开更多
Questions can be classified from different perspectives： grammatical form, communicative value, content orientation and cognitive level. In language pedagogy, text-based questioning as both an attention drawing devic...Questions can be classified from different perspectives： grammatical form, communicative value, content orientation and cognitive level. In language pedagogy, text-based questioning as both an attention drawing device and a form of learning tasks serves text instruction. Therefore, language teachers preparing text-based questioning should take into consideration all dimensions of questions, especially cognitive requirement and communicative character. In addition, interaction between learner, text and the world can be achieved by the adoption of both about-the-text and beyond-the-text questions in teachers＇ text-based question construction.展开更多
Classroom questioning is one of the most important parts of teaching activities, and also the most frequently used method to carry on classroom interactions between teachers and students. English teaching process is t...Classroom questioning is one of the most important parts of teaching activities, and also the most frequently used method to carry on classroom interactions between teachers and students. English teaching process is the process of"asking"and"answering"between teachers and students. Teachers should not only pay attention to the artistry of questioning, but also attach great importance to the strategy of asking questions. Appropriate teachers' questions are conducive to cultivate students' divergent thinking, and encourage students to better master knowledge by thinking and discussing, thus contributing to classroom interactions move towards a climax.展开更多
Case-based learning(CBL) is gradually replacing the traditional lecturing-based learning in nursing English teaching.In the process of CBL, selecting and compiling a good case is key to the success of CBL. In the mean...Case-based learning(CBL) is gradually replacing the traditional lecturing-based learning in nursing English teaching.In the process of CBL, selecting and compiling a good case is key to the success of CBL. In the meantime, designing questions is an important factor for successful CBL. In this article, we discuss how to select and compile cases and how to design questions in CBL used in Medical-nursing English Teaching.展开更多
How to Differentiate and Treat Bi-syndrome by Acupuncture and Moxibustion?Bi-syndrome is the syndrome due to invasion of the exogenous pathogenic factors of wind, cold and dampness, which obstruct the channels and col...How to Differentiate and Treat Bi-syndrome by Acupuncture and Moxibustion?Bi-syndrome is the syndrome due to invasion of the exogenous pathogenic factors of wind, cold and dampness, which obstruct the channels and collaterals, leading to stagnated flow of qi and blood, characterized by such clinical manifestations as aching pain, numbness, heaviness, limited flexion and extension of the muscles, tendons and joints, or swelling and burning heat of the joints. This syndrome includes rheumatic arthritis, rheumatoid arthritis, osseous arthritis, and various neuralgia. The endogenous causative factors for the occurrence of Bi-syndrome are insufficiency of yang-qi, essence and blood, while the exogenous causative factors are the pathogenic wind, cold, and dampness. At the initial stage of the disease, the excessiveness of pathogen usually prevails, and the disease tends to be located in the limbs, skin and muscles, and channels and collaterals; while at the chronic stage, there often exists deficiency of the vital-qi or deficiency and excess intermixed, and the disease tends to be located deeper in the tendons and bones or in the zang-fu organs.展开更多
Questions which were conventionally designed to check reading comprehension can also be used to enhance understanding. Different types of questions can be designed to achieve different purposes in reading. While desig...Questions which were conventionally designed to check reading comprehension can also be used to enhance understanding. Different types of questions can be designed to achieve different purposes in reading. While designing questions, teachers should take into consideration such points as the language used, manner of presentation and types of questions etc. Moreover, once questions have been designed, it’s essential for teachers to think about the techniques for the use of these questions. If appro- priately used, questions contribute greatly to students’ understanding of what they’ re reading by helping to explore the meaning that language conveys, in addition to developing proper reading skills. Therefore, teachers should be able to teach reading with well-designed questions so that the ultimate goal of understanding the text is likely to be achieved.展开更多
文摘Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?
文摘Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CASTopic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?
基金Supported by National Key Research and Development Program:2017YFC1703606Shenzhen Science and Technology Program:JCYJ20210324120804012+1 种基金2021 Luohu Soft Science Research Program Project:LX202101022022 Luohu Soft Science Research Program Project:LX202202128。
文摘Determining clinical questions is fundamental to the development of clinical practice guidelines(CPGs),which bridges the initial phases and the final recommendations.It is essential for evidence retrieval and the formulation of recommendations.The scientific rigor and precision in determination of clinical questions directly influence the future implementation and applicability of guidelines.In 2020,the World Federation of Acupuncture-Moxibustion Societies initiated the project of clinical practice guideline on acupuncture and moxibustion for adult major depressive disorder(mild-moderate degree)to address clinical and medical decision-making issues in acupuncture treatment for adult mild to moderate major depressive disorder.This CPG provides systematic recommendations based on clinical evidence,patient values,and other factors,aiding decision-makers,clinicians,and patients in selecting appropriate interventions.This paper discusses and analyzes the determination process of clinical questions,and the related issues during the development of this guideline,aiming to provide a reference for determining clinical questions and developing CPGs in the field of acupuncture and exploring more scientific tools and methods for determining clinical questions in future CPGs.
文摘Editors Yang Wang,Xi'an Jiaotong University Dongbo Shi,Shanghai Jiaotong University Ye Sun,University College London Zhesi Shen,National Science Library,CAS Topic of the Special Issue What are the top questions towards better science and innovation and the required data to answer these questions?
文摘In literature,differences in the description of female and male characters have been noticeable for a long time.In this study,the novel Jane Eyre is uses as a material to investigate whether there are in fact any significant differences in the questions Mr.Rochester and Jane use and how the questions function to portray these two main characters.
文摘Obesity is recognized as the second highest risk factor for cancer. The pathogenic mechanisms underlying tobaccorelated cancers are well characterized and efective programs have led to a decline in smoking and related cancers, but there is a global epidemic of obesity without a clear understanding of how obesity causes cancer. Obesity is heterogeneous, and approximately 25% of obese individuals remain healthy(metabolically healthy obese, MHO), so which fat deposition(subcutaneous versus visceral, adipose versus ectopic) is "malignant"? What is the mechanism of carcinogenesis? Is it by metabolic dysregulation or chronic inflammation? Through which chemokines/genes/signaling pathways does adipose tissue influence carcinogenesis? Can selective inhibition of these pathways uncouple obesity from cancers? Do all obesity related cancers(ORCs) share a molecular signature? Are there common(overlapping) genetic loci that make individuals susceptible to obesity, metabolic syndrome, and cancers? Can we identify precursor lesions of ORCs and will early intervention of high risk individuals alter the natural history? It appears unlikely that the obesity epidemic will be controlled anytime soon; answers to these questions will help to reduce the adverse efect of obesity on human condition.
基金National Social Science Fund of China,No.19ZDA096National Natural Science Foundation of China,No.41971234,No.41971235+1 种基金Postgraduate Research and Practice Innovation Project of Jiangsu Province,No.KYCX21_0039Open Fund of Key Laboratory of Coastal Zone Exploitation and Protection,Ministry of Natural Resources,No.2021CZEPK07。
文摘As the world’s largest developing country,the ability of China’s agricultural resource utilization to effectively support the current and future food security goals has been affected by a variety of factors(e.g.,transformed supply channels,tightening international situation and frequent emergencies)in recent years and has attracted extensive attention from the academic community subject to multiple factors.This study uses literature review,statistical analysis,and spatial analysis methods to systematically explore China’s food security situation in the context of farmland resource constraints.It is found that the demand-side pressures such as demographic changes,social class differentiation,and dietary structure adjustments derived from economic growth and rapid urbanization have placed extremely high expectations on food supply.However,the quantitative restrictions,utilization ways,and health risks of farmland resources on the supply side constitute a huge hidden concern that affects the stability of food production.Although China’s farmland protection system is undergoing a transition from focusing on quantity management to sustainable use,the matching and coordinating demand pressure and supply capacity for food security is unbalanced.Therefore,facing uncertain future development scenarios,policymakers should focus on building a resilient space for China’s farmland protection to withstand the interference of major emergencies.The existing farmland protection space policy can be integrated by establishing a national farmland strategic reserve system(based on resilient space),and further development of targeted use control measures for zoning,grading,and classification will help realize sustainable China’s farmland resources use.
基金supported by National Nature Science Foundation(No.61501529,No.61331013)National Language Committee Project of China(No.ZDI125-36)Young Teachers'Scientific Research Project in Minzu University of China.
文摘With the emergence of large-scale knowledge base,how to use triple information to generate natural questions is a key technology in question answering systems.The traditional way of generating questions require a lot of manual intervention and produce lots of noise.To solve these problems,we propose a joint model based on semi-automated model and End-to-End neural network to automatically generate questions.The semi-automated model can generate question templates and real questions combining the knowledge base and center graph.The End-to-End neural network directly sends the knowledge base and real questions to BiLSTM network.Meanwhile,the attention mechanism is utilized in the decoding layer,which makes the triples and generated questions more relevant.Finally,the experimental results on SimpleQuestions demonstrate the effectiveness of the proposed approach.
基金supported in part by JST,CREST to Y.K.Special Coordination Funds for Promoting Science and Technology from the Ministry of Education,Culture,Sports,Science and Technology of the Japanese Government to Y.K.a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology of the Japanese Government to Y.K.(25460399)
文摘Fatigue is best defined as difficulty in initiating or sustaining voluntary activities, and is thought to be accompanied by deterioration of performance. Fatigue can be caused by many factors such as physical and mental stress, disturbance in the circadian rhythm, and various diseases. For example, following the flu or other types of infections, everyone has experienced a sense of fatigue that can last for days or weeks. The fatigue sensation is thought to be one of the signals for the body to suppress physical activity in order to regain health. The mechanism of induction of the fatigue sensation following viral infection has not been well understood. Although fatigue was once thought to be caused by fever, our recent study with an animal model of viral infection demonstrated that the fatigue sensation is caused not by fever, but rather,
文摘The frequent occurrence of echo questions in people's daily conversation has not arouse enough interest in linguists yet; meanwhile, different scholars hold different views when it comes to such questions as how far the boundary of echo questions should extend, how they should be classified, etc. The following paper gives the echo question a new definition and classification. It hopes to provide a more persuasive reference of future researchers.
文摘Questions can be classified from different perspectives： grammatical form, communicative value, content orientation and cognitive level. In language pedagogy, text-based questioning as both an attention drawing device and a form of learning tasks serves text instruction. Therefore, language teachers preparing text-based questioning should take into consideration all dimensions of questions, especially cognitive requirement and communicative character. In addition, interaction between learner, text and the world can be achieved by the adoption of both about-the-text and beyond-the-text questions in teachers＇ text-based question construction.
文摘Classroom questioning is one of the most important parts of teaching activities, and also the most frequently used method to carry on classroom interactions between teachers and students. English teaching process is the process of"asking"and"answering"between teachers and students. Teachers should not only pay attention to the artistry of questioning, but also attach great importance to the strategy of asking questions. Appropriate teachers' questions are conducive to cultivate students' divergent thinking, and encourage students to better master knowledge by thinking and discussing, thus contributing to classroom interactions move towards a climax.
文摘Case-based learning(CBL) is gradually replacing the traditional lecturing-based learning in nursing English teaching.In the process of CBL, selecting and compiling a good case is key to the success of CBL. In the meantime, designing questions is an important factor for successful CBL. In this article, we discuss how to select and compile cases and how to design questions in CBL used in Medical-nursing English Teaching.
文摘How to Differentiate and Treat Bi-syndrome by Acupuncture and Moxibustion?Bi-syndrome is the syndrome due to invasion of the exogenous pathogenic factors of wind, cold and dampness, which obstruct the channels and collaterals, leading to stagnated flow of qi and blood, characterized by such clinical manifestations as aching pain, numbness, heaviness, limited flexion and extension of the muscles, tendons and joints, or swelling and burning heat of the joints. This syndrome includes rheumatic arthritis, rheumatoid arthritis, osseous arthritis, and various neuralgia. The endogenous causative factors for the occurrence of Bi-syndrome are insufficiency of yang-qi, essence and blood, while the exogenous causative factors are the pathogenic wind, cold, and dampness. At the initial stage of the disease, the excessiveness of pathogen usually prevails, and the disease tends to be located in the limbs, skin and muscles, and channels and collaterals; while at the chronic stage, there often exists deficiency of the vital-qi or deficiency and excess intermixed, and the disease tends to be located deeper in the tendons and bones or in the zang-fu organs.
文摘Questions which were conventionally designed to check reading comprehension can also be used to enhance understanding. Different types of questions can be designed to achieve different purposes in reading. While designing questions, teachers should take into consideration such points as the language used, manner of presentation and types of questions etc. Moreover, once questions have been designed, it’s essential for teachers to think about the techniques for the use of these questions. If appro- priately used, questions contribute greatly to students’ understanding of what they’ re reading by helping to explore the meaning that language conveys, in addition to developing proper reading skills. Therefore, teachers should be able to teach reading with well-designed questions so that the ultimate goal of understanding the text is likely to be achieved.
