Objective To systematically evaluate the quality of pharmacoeconomics on hypertension management,and provide reference for promoting the development of pharmacoeconomics in China.Methods Some Chinese databases includi...Objective To systematically evaluate the quality of pharmacoeconomics on hypertension management,and provide reference for promoting the development of pharmacoeconomics in China.Methods Some Chinese databases including CNKI,VIP,Wanfang,as well as international databases such as PubMed and Web of Science were searched to collect studies of economic evaluation on hypertension management in China.The quality of health economic studies(QHES)scale was used to assess the quality of the literature and to analyze the current situation and shortcomings of pharmacoeconomics in the field of hypertension in China.Results and Conclusion A total of 363 articles were included in this study.The quality assessment results showed that the average score of pharmacoeconomics on hypertension management was 42.54 points.The quality of literature published by medical institutions was significantly lower than that published by universities/research institutes(41.25 vs.54.68,P<0.05).Among the 363 articles,3.31%(12 articles)were of high quality(75-100 points),29.20%(106 articles)were of moderate quality(50-74 points),66.12%(240 articles)were of low quality(25-49 points),and 1.38%(5 articles)were of extremely low quality(0-24 points).These papers have such problems as unclear research perspectives,single research methods,ambiguous data sources,inappropriate study duration for disease characteristics,and insufficient sensitivity analysis factors.Overall,the quality evaluation of pharmacoeconomics on hypertension management in China is generally low with poor standardization,which should be improved in the future.展开更多
Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-ma...Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-making.Methods The economic evaluation literature on drugs for type 2 diabetes based on the Chinese population were searched from CNKI,Wanfang,VIP and PubMed databases.The literature that met the inclusion criteria was selected,and the key research elements were extracted.Meanwhile,the quality of health economics studies(QHES)was used to evaluate the quality of the literature.Results and Conclusion A total of 325 articles(296 in Chinese and 29 in English)were included.Most of the studies were conducted by medical institutions(247 articles,76.0%)and they used cost-effectiveness analysis(295 articles,90.8%).However,most of the included literature did not report study perspective(267 articles,90.2%).The average QHES score of the included literature was 57.29,and the quality of the literature was concentrated in“low quality”(123 articles,37.8%)and“average quality”(138 articles,42.5%).Literature published in English journals,or using modeling methods,or from universities had relatively higher quality.The quality of economic evaluation literature on drugs for type 2 diabetes based on the Chinese population is generally low at present.There are many problems,such as single research institutions and methods,lack of research perspectives,and no sensitivity analysis.展开更多
Topological phases in condensed matter have become one of the most vibrant branches in contemporary physics.Reaching back more than four decades,the discovery of the quantum Hall effect(QHE)in GaAs/GaAlAs semiconducto...Topological phases in condensed matter have become one of the most vibrant branches in contemporary physics.Reaching back more than four decades,the discovery of the quantum Hall effect(QHE)in GaAs/GaAlAs semiconductor heterostructures has been a milestone for the field of topological quantum states[1].展开更多
We review our most recent research on quantum transport,organizing the review according to the intensity of the magnetic field and focus mostly on topological semimetals and topological insulators.We first describe th...We review our most recent research on quantum transport,organizing the review according to the intensity of the magnetic field and focus mostly on topological semimetals and topological insulators.We first describe the phenomenon of quantum transport when a magnetic field is not present.We introduce the nonlinear Hall effect and its theoretical descriptions.Then,we discuss Coulomb instabilities in 3D higher-order topological insulators.Next,we pay close attention to the surface states and find a function to identify the axion insulator in the antiferromagnetic topological insulator MnBi2Te4.Under weak magnetic fields,we focus on the decaying Majorana oscillations which has the correlation with spin−orbit coupling.In the section on strong magnetic fields,we study the helical edge states and the one-sided hinge states of the Fermi-arc mechanism,which are relevant to the quantum Hall effect.Under extremely large magnetic fields,we derive a theoretical explanation of the negative magnetoresistance without a chiral anomaly.Then,we show how magnetic responses can be used to detect relativistic quasiparticles.Additionally,we introduce the 3D quantum Hall effect’s charge-density wave mechanism and compare it with the theory of 3D transitions between metal and insulator driven by magnetic fields.展开更多
文摘Objective To systematically evaluate the quality of pharmacoeconomics on hypertension management,and provide reference for promoting the development of pharmacoeconomics in China.Methods Some Chinese databases including CNKI,VIP,Wanfang,as well as international databases such as PubMed and Web of Science were searched to collect studies of economic evaluation on hypertension management in China.The quality of health economic studies(QHES)scale was used to assess the quality of the literature and to analyze the current situation and shortcomings of pharmacoeconomics in the field of hypertension in China.Results and Conclusion A total of 363 articles were included in this study.The quality assessment results showed that the average score of pharmacoeconomics on hypertension management was 42.54 points.The quality of literature published by medical institutions was significantly lower than that published by universities/research institutes(41.25 vs.54.68,P<0.05).Among the 363 articles,3.31%(12 articles)were of high quality(75-100 points),29.20%(106 articles)were of moderate quality(50-74 points),66.12%(240 articles)were of low quality(25-49 points),and 1.38%(5 articles)were of extremely low quality(0-24 points).These papers have such problems as unclear research perspectives,single research methods,ambiguous data sources,inappropriate study duration for disease characteristics,and insufficient sensitivity analysis factors.Overall,the quality evaluation of pharmacoeconomics on hypertension management in China is generally low with poor standardization,which should be improved in the future.
文摘Objective To systematically evaluate the overall characteristics and quality of literature on economic evaluation of drugs for type 2 diabetes,and to provide recommendations for future research and related decision-making.Methods The economic evaluation literature on drugs for type 2 diabetes based on the Chinese population were searched from CNKI,Wanfang,VIP and PubMed databases.The literature that met the inclusion criteria was selected,and the key research elements were extracted.Meanwhile,the quality of health economics studies(QHES)was used to evaluate the quality of the literature.Results and Conclusion A total of 325 articles(296 in Chinese and 29 in English)were included.Most of the studies were conducted by medical institutions(247 articles,76.0%)and they used cost-effectiveness analysis(295 articles,90.8%).However,most of the included literature did not report study perspective(267 articles,90.2%).The average QHES score of the included literature was 57.29,and the quality of the literature was concentrated in“low quality”(123 articles,37.8%)and“average quality”(138 articles,42.5%).Literature published in English journals,or using modeling methods,or from universities had relatively higher quality.The quality of economic evaluation literature on drugs for type 2 diabetes based on the Chinese population is generally low at present.There are many problems,such as single research institutions and methods,lack of research perspectives,and no sensitivity analysis.
基金funded by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)through Project ID 258499086-SFB 1170,through the research unit QUAST,FOR 5249-449872909(P3)through the Würzburg-Dresden Cluster of Excellence on Complexity and Topology in Quantum Matter-ct.qmat,Project ID 390858490-EXC 2147.
文摘Topological phases in condensed matter have become one of the most vibrant branches in contemporary physics.Reaching back more than four decades,the discovery of the quantum Hall effect(QHE)in GaAs/GaAlAs semiconductor heterostructures has been a milestone for the field of topological quantum states[1].
基金This work was supported by the National Key R&D Program of China(No.2022YFA1403700)the National Natural Science Foundation of China(No.11925402)+1 种基金Guangdong province(Nos.2020KCXTD001 and 2016ZT06D348)the Science,Technology and Innovation Commission of Shenzhen Municipality(Nos.ZDSYS20170303165926217,JAY20170412152620376,and KYTDPT20181011104202253).
文摘We review our most recent research on quantum transport,organizing the review according to the intensity of the magnetic field and focus mostly on topological semimetals and topological insulators.We first describe the phenomenon of quantum transport when a magnetic field is not present.We introduce the nonlinear Hall effect and its theoretical descriptions.Then,we discuss Coulomb instabilities in 3D higher-order topological insulators.Next,we pay close attention to the surface states and find a function to identify the axion insulator in the antiferromagnetic topological insulator MnBi2Te4.Under weak magnetic fields,we focus on the decaying Majorana oscillations which has the correlation with spin−orbit coupling.In the section on strong magnetic fields,we study the helical edge states and the one-sided hinge states of the Fermi-arc mechanism,which are relevant to the quantum Hall effect.Under extremely large magnetic fields,we derive a theoretical explanation of the negative magnetoresistance without a chiral anomaly.Then,we show how magnetic responses can be used to detect relativistic quasiparticles.Additionally,we introduce the 3D quantum Hall effect’s charge-density wave mechanism and compare it with the theory of 3D transitions between metal and insulator driven by magnetic fields.
