RompecPC is a computerized program designed to create and assemble jigsaw puzzles. The program automatically records the solver’s responses as the number of pieces positioned correctly, the number of correct and inco...RompecPC is a computerized program designed to create and assemble jigsaw puzzles. The program automatically records the solver’s responses as the number of pieces positioned correctly, the number of correct and incorrect movements, the number of times that she/he attempts to move a piece to the same place (perseverations), and the latency and place to which each piece is moved or attempted to be moved. These features facilitate the implementation and evaluation of puzzles while also reducing human error. Therefore, RompePC is a useful tool for the neuropsychological assessment of visuospatial skills in both clinical and experimental research.展开更多
I wish to explore the idea that thought experiments are best accounted for as a special case of a narrative that features an interplay between puzzles and paradoxes. Furthermore, I believe the more successfully though...I wish to explore the idea that thought experiments are best accounted for as a special case of a narrative that features an interplay between puzzles and paradoxes. Furthermore, I believe the more successfully thought experiments manage to combine puzzles and paradoxes the more insightful and instructive they become. I suggest the latter kind of thought experiments also use the technique of mental variation.展开更多
Semantic relationism is a methodology proposed by Kit Fine for solving the antinomy of variables. Fine proposed the relational semantics for first-order logic, which can be used to solve Frege＇s puzzle of names. In t...Semantic relationism is a methodology proposed by Kit Fine for solving the antinomy of variables. Fine proposed the relational semantics for first-order logic, which can be used to solve Frege＇s puzzle of names. In this paper, I generalize Frege＇s puzzle to other linguistic expressions, including definite descriptions, predicates, quantifiers and modalities. I then apply Fine＇s semantic relationistic approach to these puzzles.展开更多
近三十年来,分子生物学领域包括人体基因组学、蛋白质组学等新学科和新技术蓬勃兴起,并取得了令人瞩目的成果,但深层次微观研究的局限亦日渐明显。生命科学研究的最终目的不仅是揭示生命的奥秘,更重要的是解决疾病问题,促进人类健康和...近三十年来,分子生物学领域包括人体基因组学、蛋白质组学等新学科和新技术蓬勃兴起,并取得了令人瞩目的成果,但深层次微观研究的局限亦日渐明显。生命科学研究的最终目的不仅是揭示生命的奥秘,更重要的是解决疾病问题,促进人类健康和福祉。正如诺贝尔奖得主James Black指出"分子生物学研究所获得的信息如果不结合组织器官和整体分析,则将成为孤独的分子结构和机制的一张无序的清单"。而生理学可能正是将此无序的"碎片(puzzle)"拼接成一幅有序画面的"整合者"。上世纪九十年代国际生理科学联合会(International Union of Physiological Sciences,IUPS)提出了"生理组计划",近年来随着计算机等技术的进步,生理组学研究正方兴未艾,并在生理功能的预测、药物研发模型的建立等方面发挥越来越重要的作用,但不少生理学工作者至今对于生理组学的概念仍相对生疏。高峰等教授撰写此文,从生理组学概念的提出及发展,到重点介绍生理组学与经典生理学和系统生物学之间的关系,讨论了面对当今生命科学研究的机遇和挑战,生理学家能否借助生理组学发展平台,有效地整合当今多种相关"组学"的信息,以促进现代生理学的发展,并在认识生命与健康、解决疾病问题中发挥引领作用。此文值得一读,文中提出的问题也值得读者思考。展开更多
School moral education is an important part of education, which concerns the students＇ growth and development in mental health. How to conduct moral education to help the students shape good moral norm is an issue fr...School moral education is an important part of education, which concerns the students＇ growth and development in mental health. How to conduct moral education to help the students shape good moral norm is an issue frequently discussed in the academic area. This paper probes into this issue from the formation of incorrect outlooks towards wealth and power, discusses the risks of apparently incorrect moral education, and suggests the right moral education ways, combined with some specific cases： return to the true state of morality in the concept of moralization; conduct the students＇ sense of value through teaching activities in the content of moralization; and of moralization. distinguish between good and evil in moral conflict in the way展开更多
Current image steganography methods are working by assigning an image as a cover file then embed the payload within it by modifying its pixels,creating the stego image.However,the left traces that are caused by these ...Current image steganography methods are working by assigning an image as a cover file then embed the payload within it by modifying its pixels,creating the stego image.However,the left traces that are caused by these modifications will make steganalysis algorithms easily detect the hidden payload.A coverless data hiding concept is proposed to solve this issue.Coverless does not mean that cover is not required,or the payload can be transmitted without a cover.Instead,the payload is embedded by cover generation or a secret message mapping between the cover file and the payload.In this paper,a new coverless image steganography method has been proposed based on the jigsaw puzzle image generation driven by a secret message.Firstly,the image is divided into equal rows then further divided into equal columns,creating blocks(i.e.,sub-images).Then,according to secret message bits and a proposed mapping function,each block will have tabs/blanks to get the shape of a puzzle piece creating a fully shaped jigsaw puzzle stego-image.After that,the generated jigsaw puzzle image is sent to the receiver.Experimental results and analysis show a good performance in the hiding capacity,security,and robustness compared with existing coverless image steganography methods.展开更多
BACKGROUND Microcystic adnexal carcinoma(MAC)is a rare malignant tumor of the skin that is commonly found on the face.It grows slowly and has a low mortality rate.However,for various reasons,including strong histologi...BACKGROUND Microcystic adnexal carcinoma(MAC)is a rare malignant tumor of the skin that is commonly found on the face.It grows slowly and has a low mortality rate.However,for various reasons,including strong histological invasiveness,clinical inexperience and inadequate procedure design,immediate or permanent facial deformity may occur after surgical operations.CASE SUMMARY This article describes a middle-aged female artist who was diagnosed with MAC on the left upper lip.She declined the recommended treatment plan,which included two-stage reconstruction,skin grafting,or surgery that could have resulted in obvious facial dysfunction or esthetic deformity.We accurately designed a personalized procedure involving a“jigsaw puzzle advancement flap”for the patient based on the lesion location and the estimated area of skin loss.The procedure was successful;both pathological R0 resection and immediate and long-term esthetic reconstruction effects were achieved.CONCLUSION This study suggests that when treating facial MAC or other skin malignancies,a surgical team should have sufficient plastic surgery-related knowledge and skills.An optimal surgical plan for an individual is needed to achieve good facial esthetics and functional recovery and shorten the treatment course.展开更多
文摘RompecPC is a computerized program designed to create and assemble jigsaw puzzles. The program automatically records the solver’s responses as the number of pieces positioned correctly, the number of correct and incorrect movements, the number of times that she/he attempts to move a piece to the same place (perseverations), and the latency and place to which each piece is moved or attempted to be moved. These features facilitate the implementation and evaluation of puzzles while also reducing human error. Therefore, RompePC is a useful tool for the neuropsychological assessment of visuospatial skills in both clinical and experimental research.
文摘I wish to explore the idea that thought experiments are best accounted for as a special case of a narrative that features an interplay between puzzles and paradoxes. Furthermore, I believe the more successfully thought experiments manage to combine puzzles and paradoxes the more insightful and instructive they become. I suggest the latter kind of thought experiments also use the technique of mental variation.
文摘Semantic relationism is a methodology proposed by Kit Fine for solving the antinomy of variables. Fine proposed the relational semantics for first-order logic, which can be used to solve Frege＇s puzzle of names. In this paper, I generalize Frege＇s puzzle to other linguistic expressions, including definite descriptions, predicates, quantifiers and modalities. I then apply Fine＇s semantic relationistic approach to these puzzles.
基金国家自然科学基金项目(6074100160871092)+3 种基金黑龙江省杰出青年科学基金项目(JC200611)黑龙江省自然科学基金重点项目(ZJG0705)哈尔滨工业大学校基金项目(HIT.2003.53)the High-Tech Research and Development Program of China(2007AA01Z171)~~
文摘近三十年来,分子生物学领域包括人体基因组学、蛋白质组学等新学科和新技术蓬勃兴起,并取得了令人瞩目的成果,但深层次微观研究的局限亦日渐明显。生命科学研究的最终目的不仅是揭示生命的奥秘,更重要的是解决疾病问题,促进人类健康和福祉。正如诺贝尔奖得主James Black指出"分子生物学研究所获得的信息如果不结合组织器官和整体分析,则将成为孤独的分子结构和机制的一张无序的清单"。而生理学可能正是将此无序的"碎片(puzzle)"拼接成一幅有序画面的"整合者"。上世纪九十年代国际生理科学联合会(International Union of Physiological Sciences,IUPS)提出了"生理组计划",近年来随着计算机等技术的进步,生理组学研究正方兴未艾,并在生理功能的预测、药物研发模型的建立等方面发挥越来越重要的作用,但不少生理学工作者至今对于生理组学的概念仍相对生疏。高峰等教授撰写此文,从生理组学概念的提出及发展,到重点介绍生理组学与经典生理学和系统生物学之间的关系,讨论了面对当今生命科学研究的机遇和挑战,生理学家能否借助生理组学发展平台,有效地整合当今多种相关"组学"的信息,以促进现代生理学的发展,并在认识生命与健康、解决疾病问题中发挥引领作用。此文值得一读,文中提出的问题也值得读者思考。
文摘School moral education is an important part of education, which concerns the students＇ growth and development in mental health. How to conduct moral education to help the students shape good moral norm is an issue frequently discussed in the academic area. This paper probes into this issue from the formation of incorrect outlooks towards wealth and power, discusses the risks of apparently incorrect moral education, and suggests the right moral education ways, combined with some specific cases： return to the true state of morality in the concept of moralization; conduct the students＇ sense of value through teaching activities in the content of moralization; and of moralization. distinguish between good and evil in moral conflict in the way
基金funded by“Taif University Researchers Supporting Project No.(TURSP-2020/160),Taif University,Taif,Saudi Arabia.”。
文摘Current image steganography methods are working by assigning an image as a cover file then embed the payload within it by modifying its pixels,creating the stego image.However,the left traces that are caused by these modifications will make steganalysis algorithms easily detect the hidden payload.A coverless data hiding concept is proposed to solve this issue.Coverless does not mean that cover is not required,or the payload can be transmitted without a cover.Instead,the payload is embedded by cover generation or a secret message mapping between the cover file and the payload.In this paper,a new coverless image steganography method has been proposed based on the jigsaw puzzle image generation driven by a secret message.Firstly,the image is divided into equal rows then further divided into equal columns,creating blocks(i.e.,sub-images).Then,according to secret message bits and a proposed mapping function,each block will have tabs/blanks to get the shape of a puzzle piece creating a fully shaped jigsaw puzzle stego-image.After that,the generated jigsaw puzzle image is sent to the receiver.Experimental results and analysis show a good performance in the hiding capacity,security,and robustness compared with existing coverless image steganography methods.
文摘BACKGROUND Microcystic adnexal carcinoma(MAC)is a rare malignant tumor of the skin that is commonly found on the face.It grows slowly and has a low mortality rate.However,for various reasons,including strong histological invasiveness,clinical inexperience and inadequate procedure design,immediate or permanent facial deformity may occur after surgical operations.CASE SUMMARY This article describes a middle-aged female artist who was diagnosed with MAC on the left upper lip.She declined the recommended treatment plan,which included two-stage reconstruction,skin grafting,or surgery that could have resulted in obvious facial dysfunction or esthetic deformity.We accurately designed a personalized procedure involving a“jigsaw puzzle advancement flap”for the patient based on the lesion location and the estimated area of skin loss.The procedure was successful;both pathological R0 resection and immediate and long-term esthetic reconstruction effects were achieved.CONCLUSION This study suggests that when treating facial MAC or other skin malignancies,a surgical team should have sufficient plastic surgery-related knowledge and skills.An optimal surgical plan for an individual is needed to achieve good facial esthetics and functional recovery and shorten the treatment course.
