Based on the theory of children's TCM constitution"children are Zhi yang wei chong,and Zhi yin wei zhang",combined with the etiology and pathogenesis of TCM in children with purpuric nephritis,Professor ...Based on the theory of children's TCM constitution"children are Zhi yang wei chong,and Zhi yin wei zhang",combined with the etiology and pathogenesis of TCM in children with purpuric nephritis,Professor Zhang Jun uses The four methods of"Clearing heat,dampness,tonicity,and stasis"are used to treat children with purpuric nephritis,and it is advocated that the method of"resolving blood stasis"runs through the entire treatment process,and the clinical results are quite good.展开更多
This study deals with the data of Tripterygium Wilfordii polyglucoside (1 mg/kg·day)combined with Radix Salviae Miltiorrhizae (6 - 15 g/d) in the treatment of purpuric nephritis, comparedwith a control group usin...This study deals with the data of Tripterygium Wilfordii polyglucoside (1 mg/kg·day)combined with Radix Salviae Miltiorrhizae (6 - 15 g/d) in the treatment of purpuric nephritis, comparedwith a control group using Tripterygium Wilfordii polyglucoside treatment only. The average time of ede-mad-isappearance and blood pressure-resumption to a normal range were 8. 72 ± 3. 07 and 7. 44 ± 5. 17days in the test group, which was much better than in the control group (P<0. 05) . The average time ofhematuria-disappearance in the test group and the control group were 36. 37 ± 11. 50 and 47. 73 ± 14. 03days respectively. The average time for C3 levels in the urine to resume to normal in the test group and thecontrol group were 40. 33±4. 51 and 50. 00±5. 30 days respectively (P<0.01) . The time for microcircu-lation of nail fold to return to normal after treatment in the test group and the control group were 39. 00±11. 03 and 66. 00± 9. 01 days respectively (P<0. 001) . These results indicate the effect on the test groupwas much better than that on the control group.展开更多
BACKGROUND Purpura annularis telangiectodes of Majocchi(PATM),also known as Majocchi,is a rare subclass of pigmented purpuric dermatoses.The etiology of PATM is unknown,but it seems more common in children and young w...BACKGROUND Purpura annularis telangiectodes of Majocchi(PATM),also known as Majocchi,is a rare subclass of pigmented purpuric dermatoses.The etiology of PATM is unknown,but it seems more common in children and young women.The skin lesions are mostly symmetrical ring-shaped reddish-brown macules on the lower limbs.CASE SUMMARY A 9-year-old girl,who has received treated in our department,presented with reddish-brown ring-shaped rash on both lower limbs that had been present for 6 mo.These lesions,red brownish annular or petaloid patches,were mostly found on ankles and lower limber,which do not fade when adding pressure and no feel of infiltration and no atrophy when touching those lesions.Pathological examination showed deposition of hemosiderin in papillary dermis.However,dermoscopy showed the pigmentation in the center as well as the lavender patches on the edge of lesion.The child was thus diagnosed with PATM.After diagnosis,we suggested the patient avoid strenuous exercise.she was given vitamin C tablets for oral and mometasone furoate cream for external use.Followup examinations and treatment continue to support the clinical diagnosis to date.CONCLUSION This is the first report of investigating PATM using dermoscopy,which can differentiate PATM from other diseases due to its unique microscopic feature under dermoscopy.Although PATM is harmless,it still requires long-term follow-up.Moreover,dermoscopy technique can be applied for observation of multi-site lesions and correlated with histopathology.Thus,we believe this approach could be generalized for future diagnosis of PATM.展开更多
基金The sixth batch of National Traditional Chinese Medicine Experts Academic Experience Heir Project(No.[2017]29)
文摘Based on the theory of children's TCM constitution"children are Zhi yang wei chong,and Zhi yin wei zhang",combined with the etiology and pathogenesis of TCM in children with purpuric nephritis,Professor Zhang Jun uses The four methods of"Clearing heat,dampness,tonicity,and stasis"are used to treat children with purpuric nephritis,and it is advocated that the method of"resolving blood stasis"runs through the entire treatment process,and the clinical results are quite good.
文摘This study deals with the data of Tripterygium Wilfordii polyglucoside (1 mg/kg·day)combined with Radix Salviae Miltiorrhizae (6 - 15 g/d) in the treatment of purpuric nephritis, comparedwith a control group using Tripterygium Wilfordii polyglucoside treatment only. The average time of ede-mad-isappearance and blood pressure-resumption to a normal range were 8. 72 ± 3. 07 and 7. 44 ± 5. 17days in the test group, which was much better than in the control group (P<0. 05) . The average time ofhematuria-disappearance in the test group and the control group were 36. 37 ± 11. 50 and 47. 73 ± 14. 03days respectively. The average time for C3 levels in the urine to resume to normal in the test group and thecontrol group were 40. 33±4. 51 and 50. 00±5. 30 days respectively (P<0.01) . The time for microcircu-lation of nail fold to return to normal after treatment in the test group and the control group were 39. 00±11. 03 and 66. 00± 9. 01 days respectively (P<0. 001) . These results indicate the effect on the test groupwas much better than that on the control group.
基金Supported by the Scientific Research Foundation of the Education Department of Yunnan Province,No.2023J0293。
文摘BACKGROUND Purpura annularis telangiectodes of Majocchi(PATM),also known as Majocchi,is a rare subclass of pigmented purpuric dermatoses.The etiology of PATM is unknown,but it seems more common in children and young women.The skin lesions are mostly symmetrical ring-shaped reddish-brown macules on the lower limbs.CASE SUMMARY A 9-year-old girl,who has received treated in our department,presented with reddish-brown ring-shaped rash on both lower limbs that had been present for 6 mo.These lesions,red brownish annular or petaloid patches,were mostly found on ankles and lower limber,which do not fade when adding pressure and no feel of infiltration and no atrophy when touching those lesions.Pathological examination showed deposition of hemosiderin in papillary dermis.However,dermoscopy showed the pigmentation in the center as well as the lavender patches on the edge of lesion.The child was thus diagnosed with PATM.After diagnosis,we suggested the patient avoid strenuous exercise.she was given vitamin C tablets for oral and mometasone furoate cream for external use.Followup examinations and treatment continue to support the clinical diagnosis to date.CONCLUSION This is the first report of investigating PATM using dermoscopy,which can differentiate PATM from other diseases due to its unique microscopic feature under dermoscopy.Although PATM is harmless,it still requires long-term follow-up.Moreover,dermoscopy technique can be applied for observation of multi-site lesions and correlated with histopathology.Thus,we believe this approach could be generalized for future diagnosis of PATM.
