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GC-MS Analysis of Clove Essential Oil (Syzygium aromaticum L.) as Effective Source of Biomolecules for Traditional Tomato Puree Quality Improvement
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作者 Oscar C. A. Akotowanou Euloge Sènan Adjou +7 位作者 Kowiou Aboudou Adéyèmi Berane Olubi Phillipe Sessou Franck Michels Akadiri Yessoufou Marie-Laure Fauconnier Lamine Baba-Moussa Dominique C. K. Sohounhloué 《Advances in Molecular Imaging》 2024年第4期39-49,共11页
The high-water content of tomato predisposes it to spoilage by microorganisms and led producers to carry out traditional processing of tomatoes in the form of pasteurized tomato puree. However, rapid acidification of ... The high-water content of tomato predisposes it to spoilage by microorganisms and led producers to carry out traditional processing of tomatoes in the form of pasteurized tomato puree. However, rapid acidification of these traditional tomato purees is often observed. Then, the aim of this study was to evaluate the efficacy of the essential oil extracted from Clove (Syzygium aromaticum L.) in the improvement of traditional tomato puree producing technology. Essential oil of Clove (Syzygium aromaticum L.) was extracted by hydrodistillation and its chemical composition was determined by GC and GC/MS. Different types of traditional tomato puree were produced by the modification of the traditional processing technology and the addition of the essential oil introduction step, followed by manual stirring during the process. Based on previous studies, two different essential oil concentrations (5.0 and 7.5 μL∙g−1) were investigated. Physicochemical, microbiological and nutritional analyzes were performed in order to evaluate the quality of the traditional tomato puree produced. Results obtained revealed that the essential oil of Syzygium aromaticum investigated has a chemical composition characterized by the presence of eugenol (59.11%) and eugenol acetate (33.73%). Good stabilization of the physicochemical, microbiological and nutritional parameters in traditional tomato puree samples preserved with essential oil of Syzygium aromaticum were observed when compared to control. The essential oil of Clove, with his biological property, offers a novel approach to the management of traditional tomato puree during storage. 展开更多
关键词 Essential Oil Syzygium aromaticum Tomato puree Process Quality BENIN
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Determination of the Bacteriological Quality of Weaning Porridges and Purees Consumed by Children Aged 6 to 24 Months at the Guinea Institute of Nutrition and Child Health
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作者 Nènè Adama Sow Aminatou Touré +2 位作者 Salimatou Diallo Ahmadou Sadio Diallo Amadou Sylla 《Food and Nutrition Sciences》 2024年第12期1345-1356,共12页
The feeding of children during weaning must be of good quality, this is essential, and it must not be a source of contamination to ensure the well-being of children. The objective of this work was to determine the bac... The feeding of children during weaning must be of good quality, this is essential, and it must not be a source of contamination to ensure the well-being of children. The objective of this work was to determine the bacteriological quality of the porridges and purees of weaning consumed by children from 6 to 24 months at the INSE of Guinea. For this, a descriptive study of analytical type was carried out over a period of 4 months at the INSE of Guinea. This study found that total mesophilic flora, faecal streptococci, staphylococci, and salmonella were consistent with sanitary standards in Plantin-enriched peanut paste and groundnut paste samples. They had respective bacteriological qualities of 90% and 60%. Fecal coliform contamination and ASR were observed respectively in the samples of rice husk remnants enriched with peanut paste and planting banana purée with respective values 50% and 40%. From the point of view of tampering, the samples of rice ground meal enriched with groundnut paste and Plantin banana purees were severely affected by the total coliforms at 40% and 60% respectively. In the end, poor hygiene practice during preparation increases the risk of food contamination;however, hygienic measures must be taken to improve the hygienic quality of food to maintain good health of children. 展开更多
关键词 Bacteriological Quality Porridges purees INSE of Guinea
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Optimization of Process Parameters of Continuous Microwave Drying Raspberry Puree Based on RSM and ANN-GA 被引量:2
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作者 Zheng Xian-zhe Gao Feng +2 位作者 Fu Ke-sen Lu Tian-lin Zhu Chong-hao 《Journal of Northeast Agricultural University(English Edition)》 CAS 2023年第1期69-84,共16页
To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexe... To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexes(average temperature,average moisture content,average retention rate of the total anthocyanin content,temperature contrast value,and moisture dispersion value)were investigated via the response surface method(RSM)and the artificial neural network(ANN)with genetic algorithm(GA).The results showed that the microwave intensity and drying time dominated the changes of evaluation indexes.Overall,the ANN model was superior to the RSM model with better estimation ability,and higher drying uniformity and anthocyanin retention rate were achieved for the ANN-GA model compared with RSM.The optimal parameters were microwave intensity of 5.53 W•g^(-1),air velocity of 1.22 m·s^(-1),and drying time of 5.85 min.This study might provide guidance for process optimization of microwave drying berry fruits. 展开更多
关键词 raspberry puree continuous microwave drying response surface method(RSM) artificial neural network(ANN) genetic algorithm(GA)CLC number:TG376 Document code:A Article ID:1006-8104(2023)-01-0069-16
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Determination of the cut-off score of an endoscopic scoring method to predict whether elderly patients with dysphagia can eat pureed diets
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作者 Torao Sakamoto Akira Horiuchi +3 位作者 Toshiyuki Makino Masashi Kajiyama Naoki Tanaka Masamitsu Hyodo 《World Journal of Gastrointestinal Endoscopy》 CAS 2016年第6期288-294,共7页
AIM: To identify the cut-off value for predicting the ability of elderly patients with dysphagia to swallow pureed diets using a new endoscopy scoring method. METHODS: Endoscopic swallowing evaluation of pureed diets ... AIM: To identify the cut-off value for predicting the ability of elderly patients with dysphagia to swallow pureed diets using a new endoscopy scoring method. METHODS: Endoscopic swallowing evaluation of pureed diets were done in patients ≥ 65 years with dysphagia. The Hyodo-Komagane score for endoscopic swallowing evaluation is expressed as the sum(0-12) of four degrees(0-3) with four parameters:(1) salivary pooling in the vallecula and piriform sinuses;(2) the response of glottal closure reflex induced by touching the epiglottis with the endoscope;(3) the location of the bolus at the time of swallow onset assessed by "white-out" following swallowing of test jelly; and(4) pharyngeal clearance after swallowing of test jelly. We used receiver operating characteristic(ROC) curve analysis to retrospectively analyze the association between the total score and successful oral intake of pureed diets. RESULTS: One hundred and seventy-eight patients were enrolled including 113 men(63%), mean age 83 years(range, 66-98). One hundred and twenty-six patients(71%) were able to eat pureed diets during the observation period(mean ± SD, 19 ± 14 d). In ROC analysis, the cut-off value of the score for eating the pureed diets was 7(sensitivity = 0.98; specificity = 0.91).CONCLUSION: The Hyodo-Komagane endoscopic score is useful to predict the ability to eat pureed diets in elderly patients with dysphagia. 展开更多
关键词 DYSPHAGIA Endoscopy pureed DIETS Percutaneous ENDOSCOPIC GASTROSTOMY
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Assessment of Patulin Content in Apple Puree and Apple and Fruit Puree by High Performance Liquid Chromatography
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作者 Monica Catana Luminita Catana +5 位作者 Enuta Iorga Mioara Negoita Valentin Ionescu Nastasia Belc Dragos Efstatiade Hassan Y. Aboul-Enein 《Journal of Environmental Science and Engineering(A)》 2016年第7期371-381,共11页
An analytical method was developed and validated for determination of patulin in apple puree by HPLC. Extraction and clean-up ofpatulin from clear extract are achieved on AFFINIMIP SPEPATULIN cartridges. Patulin is th... An analytical method was developed and validated for determination of patulin in apple puree by HPLC. Extraction and clean-up ofpatulin from clear extract are achieved on AFFINIMIP SPEPATULIN cartridges. Patulin is then separated on a Hypersil GOLD column 150 mm × 4 mm, 5 μtmand detected at 276 nm. The recovery in the range of 5 μg/kg-80 μg/kg was 81.47%. The limit of detection (LOD) was 1.36 μg/kg, and the limit of quantification (LOQ) was 4.55 μg/kg. The patulin content of the commercial samples of apple puree and samples of apple and fruit puree forinfants and young children as well as the samples of apple puree prepared from two apple varieties intended for processing (Jonathan, Florina) and obtained from conventional and uncertified organic cultures has been evaluated in this paper. The 44.83% patulin concentration of the analyzed samples were under the maximum level of the European Commission Regulation (EC) 1881/2006, in 46.55% of the analyzed samples patulin was not detected and in 8.62% of samples patulin concentration was lower than LOQ (European Comission, 2006a) Patulin was not detected in samples of apple puree intended for infants and young children consumption. 展开更多
关键词 PATULIN HPLC-DAD apple puree method performance parameters.
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Rosemary and Oregano Essential Oils as Natural Antioxidant to Preserve Pistachio Puree
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作者 Eda Adal Sami Eren 《Journal of Food Science and Engineering》 2019年第8期318-332,共15页
In this study,the effect of adding essential oil from different plants on prolonging the shelf life of pistachio puree was investigated.For this purpose,Rancimat method,which is one of the accelerated shelf-life test(... In this study,the effect of adding essential oil from different plants on prolonging the shelf life of pistachio puree was investigated.For this purpose,Rancimat method,which is one of the accelerated shelf-life test(ASLT)methods,was used to determine the effect of oregano(OO)and rosemary(RO)essential oils on the oxidative stability of pistachio puree.Butylated hydroxyanisole(BHA)and the control sample were used for the comparison.Concentrations used for essential oils and synthetic antioxidants were 150,300 and 600 ppm and 150 ppm,respectively.The conductivity was followed at three temperatures,110,120 and 130℃,with the addition of essential oils and BHA to pistachio puree during ASLT.Pistachio puree with essential oils showed protection against the lipid oxidation process.As the temperature increased induction time was significantly decreased during ASLT(p<0.05).The same concentrations of essential oils and BHA were also added into pistachio puree to observe the change in peroxide value(PV)and free fatty acid(FFA)value under normal storage temperatures 15,25 and 40℃.The PV and FFA increase were lower in RO,OO and BHA added pistachio puree samples during 8-month storage(p<0.05).Six hundred(600)ppm of RO added sample had an antioxidative effect as much as 150 ppm BHA added sample for both ASLT and normal storage conditions.These essential oils could be used as natural antioxidants in foods with high lipid content increasing the shelf life of these products. 展开更多
关键词 Pistachio puree lipid oxidation ANTIOXIDANT oregano ROSEMARY essential oil BHA STABILITY
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Temperature Effect on the Viscosity of Commercial Carrot Puree
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作者 Vimes-Delgadillo Jorge-Octavio, Dominguez-Rendón Ana-Cristina +2 位作者 López-del-Castillo-Lozano Micloth Dominguez-Cafiedo Irma-Liliana Galán-Méndez Frixia 《Journal of Food Science and Engineering》 2017年第10期505-513,共9页
Temperature effect was evaluated over the viscosity of commercial carrot puree in the range 30 to 60 ℃, using aBrookfield viscometer, model 4535, Lab-Line instruments. In order to perform the viscosity tests, 28 spec... Temperature effect was evaluated over the viscosity of commercial carrot puree in the range 30 to 60 ℃, using aBrookfield viscometer, model 4535, Lab-Line instruments. In order to perform the viscosity tests, 28 specimens of carrot puree froma local market were used. Totally, 72 tests (each one with a couple replicas) were performed during five minutes, using fourtemperatures (30, 40, 50 and 60 ℃), six shear rates (0.26, 0.52, 1.05, 2.09, 5.24 and 10.47 s1) and three spindles (4, 5 and 6).Statistical analysis was performed using LSD and Duncan tests with a confidence interval of 95% (p value of 0.05). In the currentstudy, it was observed that an increase in the temperature triggers a reduction in the viscosity of the carrot specimens analyzed,although the samples tested at 60℃ were deviated from this trend, which may be due to denaturation of the starch containing carrotsamples at such temperature. Multiple biochemical and micro-structural changes inside the food specimens may begin to occur belowand over the physiological range (20-45 ℃). Experimental data were analyzed with Power Law model in order to obtain the bestfitted parameters as a function of shear rate: It was observed that the consistent index (k) decreased with an increment in thetemperature; while all the values of parameter "n" lesser than one, which means that the puree samples behaved as a pseudo-plasticfluid. Besides that, an Arrhenius model was used to fit the parameters as a function of temperature: Parameter A was lower usingtheexperimental data at shear rates of 10.47 s-1. The modeling performed may be helpful for the appropriate selection of some processvariables, as the shear rate and operation temperature, used for the production of carrot puree; all this is in order to obtain the finishedproduct with the desired consistency. 展开更多
关键词 FOOD rheology viscosity temperature CARROT puree.
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Effect of Soursop Puree and Gum Arabic on the Sensory Properties of Non-Dairy Coconut Milk-Based Ice Cream
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作者 Sarah N. Mulwa Symon M. Mahungu Benard K. Muinde 《Food and Nutrition Sciences》 2023年第7期670-686,共17页
Coconut (Cocos nucifera) milk-based ice cream is one of the innovative non-dairy milk products gaining popularity among consumers. The objective was to develop coconut milk-based ice cream incorporated with soursop (A... Coconut (Cocos nucifera) milk-based ice cream is one of the innovative non-dairy milk products gaining popularity among consumers. The objective was to develop coconut milk-based ice cream incorporated with soursop (Annona muricata) fruit puree and gum Arabic from Acacia senegal var. kerensis, conduct a sensory evaluation using descriptive tests by trained panelists (n = 9) then evaluate for consumer acceptability by semi trained panelists (n = 30). A seven-point hedonic scale for colour, taste, flavour, texture and overall acceptability was used. The data obtained was subjected to analysis of variance (ANOVA) and the means were separated to determine their significance differences. Principal Component Analysis (PCA) was done for factor reduction to make it easy for the multi-dimensional descriptive data to be interpreted. PCA results indicated that unit increase in soursop and gum Arabic in the ice cream led to 83.1% increase in starchy taste, 78.3% increase in consistency and 73.6% decrease in coconut aroma. For consumer acceptability test, the obtained results showed that, soursop puree addition at successive levels led to a statistically significant effect (p < 0.05) on colour, flavour, texture, taste and overall acceptability while of gum Arabic incorporation was not significant (p > 0.05) for all attributes. The effect due to interaction between gum Arabic and soursop puree at the different levels however was significant for colour, flavour and texture but not significant for taste and overall acceptability. Our results therefore point to a potential application of soursop fruit and gum Arabic as alternative ingredients in the manufacture of a non-dairy ice cream with desirable sensory properties that would expand the variety of options consumers can choose from. 展开更多
关键词 Consumer Acceptability Ice Cream Non-Dairy Sensory Properties Soursop puree
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Evaluation of Kenyan Orange Fleshed Sweet Potato (Ipomoea batatas Lam,) Purees for Functional Food Production
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作者 Muchiri M. Njeri McCartney Anne L. 《Journal of Life Sciences》 2014年第2期128-133,共6页
Consumption of functional foods with health promoting benefits and/or disease prevention has been on the increase globally. The study aimed at evaluating the potential of utilizing Kenyan orange fleshed sweet potato ... Consumption of functional foods with health promoting benefits and/or disease prevention has been on the increase globally. The study aimed at evaluating the potential of utilizing Kenyan orange fleshed sweet potato (Ipomoea batatas Lam.) for functional food production with aesthetics benefits. Purees from three different varieties of orange fleshed sweet potato (OFSP) were analyzed for nutritional, physicochemical and microbial quality, The findings of the study show that the three purees were all microbiologically safe and of near neutral pH, but differed significantly (P 〈 0.05) in nutrient content (dry matter content, 12.76-28.23%; crude fiber, 1.37-2.90% fresh weight basis (FWB); 13-carotene, 0.94-9.27 mg/100g dry weight basis (DWB); starch, 10.20-18.30% FWB & total sugar 27.08-31.76% DWB). The purees had attractive appearance (ranging from yellow to dark orange), with varying significantly different spectrophotometer hunters color scale (P 〈 0.05), and flow ability. Conclusions from the findings show great potential of utilizing the varying properties of OFSP puree to produce enriched functional food products such as probiotic/prebiotic dairy, beverages, bakery and baby foods. 展开更多
关键词 Orange fleshed sweet potato puree functional foods sustainable nutrition.
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Determining the effect of high hydrostatic pressure on the refrigerated stability of avocado puree
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作者 Sinan Uzunlu 《Food Production, Processing and Nutrition》 2024年第1期319-326,共8页
The present study aimed to extend refrigerated stability of locally grown avocado fruit by applying High Hydrostatic Pressure(HHP)treatment.HHP was applied at 600 MPa for 3 min to avocado puree and stored at 4℃ for 2... The present study aimed to extend refrigerated stability of locally grown avocado fruit by applying High Hydrostatic Pressure(HHP)treatment.HHP was applied at 600 MPa for 3 min to avocado puree and stored at 4℃ for 28 days.Physicochemical(colour CIE L^(*),a^(*),b^(*),total oil amount,chlorophyll,pH,moisture)and microbiological(mesophilic,yeast-mould)analyses were performed at seven-day intervals on both control(untreated)and HHP-treated sample packs.It could be judged that HHP treatment effectively controlled the colour indices,preventing undesired changes during the cold storage period of avocado puree.In conclusion,this study demonstrated that HHP-processed avocado puree exhibited stability for 28 days compared to unprocessed puree at 4℃.The shelf-life stability of avocado puree under chilled conditions was extended from 7 to 28 days. 展开更多
关键词 AVOCADO Cold pasteurisation High hydrostatic pressure puree
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Interpretable Machine Learning Method for Compressive Strength Prediction and Analysis of Pure Fly Ash-based Geopolymer Concrete
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作者 SHI Yuqiong LI Jingyi +1 位作者 ZHANG Yang LI Li 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2025年第1期65-78,共14页
In order to study the characteristics of pure fly ash-based geopolymer concrete(PFGC)conveniently,we used a machine learning method that can quantify the perception of characteristics to predict its compressive streng... In order to study the characteristics of pure fly ash-based geopolymer concrete(PFGC)conveniently,we used a machine learning method that can quantify the perception of characteristics to predict its compressive strength.In this study,505 groups of data were collected,and a new database of compressive strength of PFGC was constructed.In order to establish an accurate prediction model of compressive strength,five different types of machine learning networks were used for comparative analysis.The five machine learning models all showed good compressive strength prediction performance on PFGC.Among them,R2,MSE,RMSE and MAE of decision tree model(DT)are 0.99,1.58,1.25,and 0.25,respectively.While R2,MSE,RMSE and MAE of random forest model(RF)are 0.97,5.17,2.27 and 1.38,respectively.The two models have high prediction accuracy and outstanding generalization ability.In order to enhance the interpretability of model decision-making,we used importance ranking to obtain the perception of machine learning model to 13 variables.These 13 variables include chemical composition of fly ash(SiO_(2)/Al_(2)O_(3),Si/Al),the ratio of alkaline liquid to the binder,curing temperature,curing durations inside oven,fly ash dosage,fine aggregate dosage,coarse aggregate dosage,extra water dosage and sodium hydroxide dosage.Curing temperature,specimen ages and curing durations inside oven have the greatest influence on the prediction results,indicating that curing conditions have more prominent influence on the compressive strength of PFGC than ordinary Portland cement concrete.The importance of curing conditions of PFGC even exceeds that of the concrete mix proportion,due to the low reactivity of pure fly ash. 展开更多
关键词 machine learning pure fly ash geopolymer compressive strength feature perception
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Microstructure and Mechanical Properties of Explosively Welded Nickel/Steel Composite Plate Interface
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作者 Li Yan Wang Guicheng +3 位作者 Zhang Wenbin Yang Haijuan Li Jucai Liu Cuirong 《稀有金属材料与工程》 北大核心 2025年第8期1971-1979,共9页
High-performance pure nickel N6/steel 45#composite plate(N6/45#)was prepared using explosive welding technique.The microstructure of the interface and nearby regions was characterized and analyzed by optical microscop... High-performance pure nickel N6/steel 45#composite plate(N6/45#)was prepared using explosive welding technique.The microstructure of the interface and nearby regions was characterized and analyzed by optical microscope,scanning electron microscope,electron backscatter diffraction,and mechanical property testing,and the microstructural features and mechanical properties of the explosive welding interface were explored.The results show that along the direction of explosive welding,the pure nickel N6/steel 45#composite plate interface gradually evolves from a flat bond to a typical wavy bond.The grains at the crests and troughs exhibit high heterogeneity,and the closer to the interface,the finer the grains.Recrystallization and low-stress deformation bands are formed at the bonding interface.Nanoindentation tests reveal that plastic deformation occurs in the interfacial bonding zone,and the nanohardness values in the crest regions are higher than that in the trough regions.The tensile strength of the N6/45#interface is 599.8 MPa,with an average shear strength of 326.3 MPa.No separation phenomenon is observed between N6 and 45#after the bending test. 展开更多
关键词 explosive welding pure nickel N6/steel 45#composite plate MICROSTRUCTURE NANOINDENTATION
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Another Look at the Kanmuryojukyo(“The Meditation on the Buddha of Infinite Life Sutra”)
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作者 Kenneth Lee 《Journal of Literature and Art Studies》 2025年第3期251-261,共11页
The Kanmuryojukyo(“The Meditation on the Buddha of Infinite Life Sutra”)is among the three principle canons of Pure Land Buddhism(Jpn.Jodo Shu and Jodo Shinshu)along with Amitayus Sutra and the Amitabha Sutra.Althou... The Kanmuryojukyo(“The Meditation on the Buddha of Infinite Life Sutra”)is among the three principle canons of Pure Land Buddhism(Jpn.Jodo Shu and Jodo Shinshu)along with Amitayus Sutra and the Amitabha Sutra.Although the original Sanskrit text was never found,it was translated into Chinese by a monk named Kalayasas in the 5th century and became an influential text in Mahayana Buddhism in East Asia with the help of commentaries written by notable Chinese scholars,such as Shandao in the 7th century.The sutra contains the story of Queen Vaidehi who is imprisoned by her murderous son Ajatasattu and visited by Shakyamuni Buddha in response to her prayer to be born in Amitabha’s pure land.Though in prison,the Buddha tells her how to be liberated and reborn in the pure land by meditating sixteen visualizations. 展开更多
关键词 Contemplation Sutra Amitayus Pure Land Buddhism Sukhavati Dharmakara
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第3期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad felds of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 applied mathematics MATHEMATICS mathematical research research papers pure mathematics journal overview
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Pure drug nanomedicines-where we are?
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作者 Yaoyao Lai Bing Xie +1 位作者 Wanting Zhang Wei He 《Chinese Journal of Natural Medicines》 2025年第4期385-409,共25页
Pure drug nanomedicines(PDNs)encompass active pharmaceutical ingredients(APIs),including macromolecules,biological compounds,and functional components.They overcome research barriers and conversion thresholds associat... Pure drug nanomedicines(PDNs)encompass active pharmaceutical ingredients(APIs),including macromolecules,biological compounds,and functional components.They overcome research barriers and conversion thresholds associated with nanocarriers,offering advantages such as high drug loading capacity,synergistic treatment effects,and environmentally friendly production methods.This review provides a comprehensive overview of the latest advancements in PDNs,focusing on their essential components,design theories,and manufacturing techniques.The physicochemical properties and in vivo behaviors of PDNs are thoroughly analyzed to gain an in-depth understanding of their systematic characteristics.The review introduces currently approved PDN products and further explores the opportunities and challenges in expanding their depth and breadth of application.Drug nanocrystals,drug-drug cocrystals(DDCs),antibody-drug conjugates(ADCs),and nanobodies represent the successful commercialization and widespread utilization of PDNs across various disease domains.Self-assembled pure drug nanoparticles(SAPDNPs),a next-generation product,still require extensive translational research.Challenges persist in transitioning from laboratory-scale production to mass manufacturing and overcoming the conversion threshold from laboratory findings to clinical applications. 展开更多
关键词 Pure drug nanomedicines Drug nanocrystals Drug-drug cocrystals Antibody-drug conjugates Drug nanoparticles Nanobodies
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Effective pure qP-wave equation and its numerical implementation in the time-space domain for 3D complicated anisotropic media
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作者 Shi-Gang Xu Xing-Guo Huang Li Han 《Petroleum Science》 2025年第4期1534-1547,共14页
Seismic anisotropy has been extensively acknowledged as a crucial element that influences the wave propagation characteristic during wavefield simulation,inversion and imaging.Transversely isotropy(TI)and orthorhombic... Seismic anisotropy has been extensively acknowledged as a crucial element that influences the wave propagation characteristic during wavefield simulation,inversion and imaging.Transversely isotropy(TI)and orthorhombic anisotropy(OA)are two typical categories of anisotropic media in exploration geophysics.In comparison of the elastic wave equations in both TI and OA media,pseudo-acoustic wave equations(PWEs)based on the acoustic assumption can markedly reduce computational cost and complexity.However,the presently available PWEs may experience SV-wave contamination and instability when anisotropic parameters cannot satisfy the approximated condition.Exploiting pure-mode wave equations can effectively resolve the above-mentioned issues and generate pure P-wave events without any artifacts.To further improve the computational accuracy and efficiency,we develop two novel pure qP-wave equations(PPEs)and illustrate the corresponding numerical solutions in the timespace domain for 3D tilted TI(TTI)and tilted OA(TOA)media.First,the rational polynomials are adopted to estimate the exact pure qP-wave dispersion relations,which contain complicated pseudo-differential operators with irrational forms.The polynomial coefficients are produced by applying a linear optimization algorithm to minimize the objective function difference between the expansion formula and the exact one.Then,the developed optimized PPEs are efficiently implemented using the finite-difference(FD)method in the time-space domain by introducing a scalar operator,which can help avoid the problem of spectral-based algorithms and other calculation burdens.Structures of the new equations are concise and corresponding implementation processes are straightforward.Phase velocity analyses indicate that our proposed optimized equations can lead to reliable approximation results.3D synthetic examples demonstrate that our proposed FD-based PPEs can produce accurate and stable P-wave responses,and effectively describe the wavefield features in complicated TTI and TOA media. 展开更多
关键词 Anisotropic media Wavefield extrapolation Pure qP-wave equation Optimization algorithm Finite-difference method Time-space domain
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Journal of Mathematical Research with Applications Guide for Authors
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《Journal of Mathematical Research with Applications》 2025年第2期F0003-F0003,共1页
Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Appli... Journal overview:Journal of Mathematical Research with Applications(JMRA),formerly Journal of Mathematical Research and Exposition(JMRE)created in 1981,one of the transactions of China Society for Industrial and Applied Mathematics,is a home for original research papers of the highest quality in all areas of mathematics with applications.The target audience comprises:pure and applied mathematicians,graduate students in broad fields of sciences and technology,scientists and engineers interested in mathematics. 展开更多
关键词 journal overview applied mathematics academic journal mathematical research research papers pure mathematics
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Empowering Intangible Cultural Heritage for Preservation and Practicality
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作者 Li Peng(Text/Photos) Pei Xunqi(Text/Photos) Huang Wenjuan(Translated) 《China's Tibet》 2025年第2期28-35,共8页
Traveling through the vast snow-covered land of Xizang,the sacred plateau,one cannot help but be captivated by the natural grandeur:the azure skies with white clouds,snowy mountains,pure lakes,forests and grasslands w... Traveling through the vast snow-covered land of Xizang,the sacred plateau,one cannot help but be captivated by the natural grandeur:the azure skies with white clouds,snowy mountains,pure lakes,forests and grasslands where herds of sheep and yaks forage and stroll leisurely. 展开更多
关键词 sheep yaks intangible cultural heritage pure lakes natural grandeur snowy mountains
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Degradation behavior of pure Mg in the physiological medium and growth mechanism of surface corrosion product films
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作者 Chenyu Wang Mingshan Sun +7 位作者 Chao Yang Haiyang Wang Jie Wang Lin Mao Yao Yang Tao Ying Paul K.Chu Xiaoqin Zeng 《Journal of Magnesium and Alloys》 2025年第4期1523-1535,共13页
Pure Mg boasting a relatively small corrosion rate is a potential biodegradable metal material for implants.However,its degradation behavior in the complex physiological environment is still a lack of understanding.In... Pure Mg boasting a relatively small corrosion rate is a potential biodegradable metal material for implants.However,its degradation behavior in the complex physiological environment is still a lack of understanding.In this work,we investigated the effect of corrosion product film layers on the degradation behavior of pure Mg in physiological environments.Pure Mg shows a faster corrosion rate in simulated body fluid(SBF)compared to NaCl solution.Hydrogen evolution experiments indicate that the degradation rate of pure Mg in SBF decreases rapidly within the first 12 h but stabilizes afterward.The rapid deposition of low-solubility calcium phosphate on the pure Mg in SBF provides protection to the substrate,resulting in a gradual decrease in the degradation rates.Consequently,the corrosion product film of pure Mg formed in SBF exhibits a layered structure,with the upper layer consisting of dense Ca_(3)(PO_(4))_(2)/Mg_(3)(PO_(4))_(2) and the lower layer consisting of Mg(OH)_(2)/MgO.Electrochemical impedance spectroscopy(EIS)shows that the resistance of the corrosion product film increases over time,indicating gradual strengthening of the corrosion resistance.The 4-week degradation results in the femoral marrow cavity of mice are consistent with the result in SBF in vitro. 展开更多
关键词 Pure Mg Physiological environment Degradation behavior Corrosion product film Calcium phosphate
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The insights into ionomer-catalyst interactions enabling high-efficiency CO_(2)electroreduction in pure water
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作者 Rui Xue Shu Yuan +8 位作者 Rongyi Wang Tianzi Bi Guiru Zhang Huiyuan Li Jiewei Yin Liuxuan Luo Shuiyun Shen Xiaohui Yan Junliang Zhang 《Journal of Energy Chemistry》 2025年第9期390-399,I0011,共11页
With the development of renewable energy,electrochemical carbon dioxide reduction reaction(CO_(2)RR)has become a potential solution for achieving carbon neutrality.However,until now,due to issues with salt precipitate... With the development of renewable energy,electrochemical carbon dioxide reduction reaction(CO_(2)RR)has become a potential solution for achieving carbon neutrality.However,until now,due to issues with salt precipitate and regeneration of the electrolyte,this technology faces challenges such as difficulty in maintaining long-term stable operation and excessive costs.The pure water CO_(2)electrolyzers are believed to be the ultimate solution to eliminate the salt depreciation and electrolyte issues.This study develops an in-situ method tailored for CO_(2)reduction in pure water.By employing distribution of relaxation times(DRT)analysis and in-situ electrochemical active surface area(ECSA)measurements,we carried out a comprehensive investigation into the mass transport and electrochemical active surface area of gas diffusion electrodes(GDE)under pure water conditions.The maximum 89%CO selectivity and high selectivity(>80%)in the range of 0-300 mA/cm^(2)were achieved using commercial Ag nanoparticles by rational design of catalyst layer.We found that ionomers influence the CO_(2)electrolyzers performance via affecting local pH,GDE-membrane interface,and CO_(2)transport,while catalyst loading mainly influences the active area and CO_(2)transport.This work provides benchmark and insights for future pure water CO_(2)electrolyzers development. 展开更多
关键词 Carbon dioxide reduction Pure water IONOMER I/C Catalyst loading
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