The accelerated pace of natural and human-driven climate change presents profound challenges for Earth's systems.Oceans and ice sheets are critical regulators of climate systems,functioning as carbon sinks and the...The accelerated pace of natural and human-driven climate change presents profound challenges for Earth's systems.Oceans and ice sheets are critical regulators of climate systems,functioning as carbon sinks and thermal reservoirs.However,they are increasingly vulnerable to warming and greenhouse gas emissions.展开更多
Erosion in slurry pumps presents a persistent challenge in industrial applications.This study examines the erosion of the static components of a 150ZJ-C42 centrifugal slurry pump,currently in operation at a beneficiat...Erosion in slurry pumps presents a persistent challenge in industrial applications.This study examines the erosion of the static components of a 150ZJ-C42 centrifugal slurry pump,currently in operation at a beneficiation plant,under varying particle conditions.Utilizing high-precision three-dimensional reverse engineering,the pump’s flow passage geometry was reconstructed to facilitate detailed erosion analysis.Focusing on the front and rear baffles of the pump chamber,as well as the volute,erosion patterns were analyzed for different particle volume concentrations and sizes.The results reveal that the highest erosion damage consistently occurs near the volute tongue,with wear being most severe in regions adjacent to the partition plate near the rear cover.Erosion damage intensity in this area correlates positively with particle diameter.Notably,the average erosion rate in the volute surpasses that of the front and rear chamber liners,reaching a value as high as 6.03×10^(-7)kg·m^(-2)·s^(-1)at a particle concentration of 9%and diameter of 0.1 mm,adversely impacting pump stability.For the pump chamber baffles,increased erosion is observed at a particle diameter of 0.05 mm under constant volume concentration conditions,while higher particle concentrations exacerbate localized erosion.展开更多
Centrifugal Pumps(CPs)are critical machine components in many industries,and their efficient operation and reliable Fault Diagnosis(FD)are essential for minimizing downtime and maintenance costs.This paper introduces ...Centrifugal Pumps(CPs)are critical machine components in many industries,and their efficient operation and reliable Fault Diagnosis(FD)are essential for minimizing downtime and maintenance costs.This paper introduces a novel FD method to improve both the accuracy and reliability of detecting potential faults in such pumps.Theproposed method combinesWaveletCoherent Analysis(WCA)and Stockwell Transform(S-transform)scalograms with Sobel and non-local means filters,effectively capturing complex fault signatures from vibration signals.Using Convolutional Neural Network(CNN)for feature extraction,the method transforms these scalograms into image inputs,enabling the recognition of patterns that span both time and frequency domains.The CNN extracts essential discriminative features,which are then merged and passed into a Kolmogorov-Arnold Network(KAN)classifier,ensuring precise fault identification.The proposed approach was experimentally validated on diverse datasets collected under varying conditions,demonstrating its robustness and generalizability.Achieving classification accuracy of 100%,99.86%,and 99.92%across the datasets,this method significantly outperforms traditional fault detection approaches.These results underscore the potential to enhance CP FD,providing an effective solution for predictive maintenance and improving overall system reliability.展开更多
Recovering waste heat is essential for primary energy savings and carbon emission reduction.To provide direct and reliable suggestions for factories to recover waste heat,energetic,economic and exergoeconomic comparis...Recovering waste heat is essential for primary energy savings and carbon emission reduction.To provide direct and reliable suggestions for factories to recover waste heat,energetic,economic and exergoeconomic comparison between direct heat exchange(DHE)and open-cycle mechanical heat pump(MHP)under various operating conditions is carried out in this work.The price ratios R_(ES)(electricity to steam)and R_(HS)(hot water to steam)are introduced to quantify regional impacts and conduct quantitative analysis.A semi-empirical formula is obtained to explore the exergoeconomic performance of the two systems.For waste heat within 373.15-423.15 K,the exergy efficiency of the DHE with a temperature difference of 10-90 K is always lower than that of the MHP with a temperature lift of 10-50 K.The economic performance of the two systems has a break-even point,depending on the operating parameters and relative prices of electricity,steam,and hot water.Under the average R_(ES)(3.8)in China,if R_(HS)is higher than 0.748,the annual revenue of the DHE is always higher,whereas the MHP is more economical when R_(HS)is lower than 0.110.In regions where R_(ES)is higher than 4.353,the annual revenue of the MHP will be negative in some cases.展开更多
In the United Kingdom, means of meeting domestic heating is being electrified to decarbonise in effort to reduce the greenhouse gases emissions from the burning of natural gas. Therefore, the uptake of heat pumps is o...In the United Kingdom, means of meeting domestic heating is being electrified to decarbonise in effort to reduce the greenhouse gases emissions from the burning of natural gas. Therefore, the uptake of heat pumps is on the increase. The operation and working principle of heat pumps must be well understood in the investigations of their impacts on the grid and the grid assets, especially distribution transformers which could be overloaded due to higher peak load demand. This work develops an operational model of heat pumps as combined space heating and domestic hot water provider implemented in MATLAB. The developed operational model of heat pumps is adaptable and repeatable for different input parameters. The developed model is used to generate daily average demand profiles of heat pumps for a typical winter weekday and a typical summer weekday. The generated demand profiles of heat pumps by the developed model compared well with the demand profiles of heat pumps generated from actual field projects which are usually expensive and time-tasking.展开更多
This contribution presents a novel wear dependent virtual flow rate sensor for single stage single lobe progressing cavity pumps. We study the wear-induced material loss of the pump components and the impact of this m...This contribution presents a novel wear dependent virtual flow rate sensor for single stage single lobe progressing cavity pumps. We study the wear-induced material loss of the pump components and the impact of this material loss on the volumetric efficiency. The results are combined with an established backflow model to implement a backflow calculation procedure that is adaptive to wear. We use a laboratory test setup with a highly abrasive fluid and operate a pump from new to worn condition to validate our approach. The obtained measurement data show that the presented virtual sensor is capable of calculating the flow rate of a pump being subject to wear during its regular operation.展开更多
To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm,special attention was paid to the first and second...To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm,special attention was paid to the first and second stage impeller guide vanes.Moreover,the impeller blade outlet width,impeller inlet diameter,blade inclination angle,and number of blades were considered for orthogonal tests.Accordingly,nine groups of design solutions were formed,and then used as a basis for the execution of numerical simulations(CFD)aimed at obtaining the efficiency values and heads for each design solution group.The influence of impeller geometric parameters on the efficiency and head was explored,and the“weight”of each factor was obtained via a range analysis.Optimal structural parameters were finally chosen on the basis of the numerical simulation results,and the performances of the optimized model were verified accordingly(yet by means of CFD).Evidence is provided that the increase in the efficiency and head of the optimized model was 12.11%and 23.5 m,respectively,compared with those of the original model.展开更多
Aviation fuel pumps of the future are required to be highly efficient and lightweight.As such,this work presents the designs of various mechanisms and structures of advanced twodimensional piston pumps for aero-engine...Aviation fuel pumps of the future are required to be highly efficient and lightweight.As such,this work presents the designs of various mechanisms and structures of advanced twodimensional piston pumps for aero-engines,and their universal kinematic design methods are detailed herein.The efficiency of various piston pump prototypes was experimentally tested at various speeds in an open circuit.The experimental results indicate that two-dimensional piston pumps have a volumetric efficiency>91%and a higher power–mass ratio than conventional fuel pumps under all the conditions studied.Furthermore,the structural and material problems encountered during testing can provide a blueprint for further improvement of the design and processing of two-dimensional piston fuel pumps.展开更多
With the increasing noise pollution, low noise optimization of centrifugal pimps has become a hot topic. However, experimental study on this problem is unacceptable for industrial applications due to unsustainable cos...With the increasing noise pollution, low noise optimization of centrifugal pimps has become a hot topic. However, experimental study on this problem is unacceptable for industrial applications due to unsustainable cost. A hybrid method that couples computational fluid dynamics （CFD） with computational aeroacoustic software is used to predict the flow-induced noise of pumps in order to minimize the noise of centrifugal pumps in actual projects. Under Langthjem＇s assumption that the blade surface pressure is the main flow-induced acoustic source in centrifugal pumps, the blade surface pressure pulsation is considered in terms of the acoustical sources and simulated using CFX software. The pressure pulsation and noise distribution in the near-cutoff region are examined for the blade-passing frequency （BPF） noise, and the sound pressure level （SPL） reached peaks near the cutoff that corresponded with the pressure pulsation in this region. An experiment is performed to validate this prediction. Four hydrophones are fixed to the inlet and outlet ports of the test pump to measure the flow-induced noise from the four-port model. The simulation results for the noise are analyzed and compared with the experimental results. The variation in the calculated noise with changes in the flow agreed well with the experimental results. When the flow rate was increased, the SPL first decreased and reached the minimum near the best efficient point （BEP）; it then increased when the flow rate was further increased. The numerical and experimental results confirmed that the BPF noise generated by a blade-rotating dipole roughly reflects the acoustic features of centrifugal pumps. The noise simulation method in current study has a good feasibility and suitability, which could be adopted in engineering design to predict and optimize the hydroacoustic behavior of centrifugal pumps.展开更多
Raising the rotational speed of an axial piston pump is useful for improving its power density;however,the churning losses of the piston increase significantly with increasing speed,and this reduces the performance an...Raising the rotational speed of an axial piston pump is useful for improving its power density;however,the churning losses of the piston increase significantly with increasing speed,and this reduces the performance and efficiency of the axial piston pump.Currently,there has been some research on the churning losses of pistons;however,it has rarely been analyzed from the perspective of the piston number.To improve the performance and efficiency of the axial piston pump,a computational fluid dynamics(CFD)simulation model of the churning loss was established,and the effect of piston number on the churning loss was studied in detail.The simulation analysis results revealed that the churning losses initially increased as the number of pistons increased;however,when the number of pistons increased from six to nine,the torque of the churning losses decreased because of the hydrodynamic shadowing effect.In addition,in the analysis of cavitation results,it was determined that the cavitation area of the axial piston pump was mainly concentrated around the piston,and the cavitation became increasingly severe as the speed increased.By comparing the simulation results with and without the cavitation model,it was observed that the cavitation phenomenon is beneficial for the reduction of churning losses.In this study,a piston churning loss test rig that can eliminate other friction losses was established to verify the accuracy of the simulation results.A comparative analysis indicated that the simulation results were consistent with the actual situation.In addition,this study also conducted a simulation study on seven and nine piston pumps with the same displacement.The simulation results revealed that churning losses of the seven pistons were generally greater than those of the nine pistons under the same displacement.In addition,regarding the same piston number and displacement,reducing the pitch circle radius of piston bores is effective in reducing the churning loss.This research analyzes the effect of piston number on the churning loss,which has certain guiding significance for the structural design and model selection of axial piston pumps.展开更多
The momentum flow exchange between the impeller and side channel produces highly turbulent flows in side channel pumps.The turbulent flows feature complex patterns of vortex structures that are partly responsible for ...The momentum flow exchange between the impeller and side channel produces highly turbulent flows in side channel pumps.The turbulent flows feature complex patterns of vortex structures that are partly responsible for the dissipation of energy losses and unsteady pressure pulsations.The concept of turbulent flows in side channel pumps requires a reliable vortex identification criterion to capture and predict the effects of the vortex structures on the performance.For this reason,the current study presents the application of the new Ω-criterion to a side channel pump model in comparison with other traditional methods such as Qand λ2 criteria.The 3D flow fields of the pump were obtained through unsteady Reynolds-averaged Navier-Stokes(RANS)simulations.Comparative studies showed that the Ω-criterion identifies the vortex of different intensities with a standard threshold,Ω=0.52.The Q and λ2 criteria required different thresholds to capture vortex of different intensities thus leads to subjective errors.Comparing theΩ-criterion intensity on different planes with the entropy losses and pressure pulsation,the longitudinal vortex plays an important role in the momentum exchange development which increases the head performance of the pump.However,the rate of exchange is impeded by the axial and radial vortices restricted in the impeller.Therefore,the impeller generates the highest entropy loss and pressure pulsation intensities which lower the output efficiency.Finally,the findings provide a fundamental background to the morphology of the vortex structures in the turbulent flows which can be dependent upon for efficiency improvement of side channel pumps.展开更多
An overview of some popular rotary and reciprocating positive displacement( PD) pump types is given with the objective of presenting and comparing the respective sizing relationships and performance features. Reciproc...An overview of some popular rotary and reciprocating positive displacement( PD) pump types is given with the objective of presenting and comparing the respective sizing relationships and performance features. Reciprocating pumps discussed are the piston and plunger types. Rotary pumps addressed are gear( external and internal),vane,lobe,screw,and liquid ring pumps. To put the relative pump sizes in perspective,attention is fixed on the rotors or reciprocating elements of PD pumps,just as impellers indicate the sizes of rotodynamic pumps. The size of a PD pump is found from a dimensionless combination of displacement flow rate,rotative speed and diameter. The flow rate,head( or pressure rise) and power are related through the component efficiencies. The cavitation coefficient,often close to unity,connects the rotor tip speed or piston speed with the required NPSH,which can also be affected by the pressure rise of the pump due to leakage across the internal clearances. Operational effects due to cavitation,ingestion of gas or abrasives,and viscous and non-Newtonian fluids are discussed.展开更多
A study on the character of pressure wave propagation was proposed for the gas liquid oxygen two-phase flow in the pipe between pumps.According to the practical working conditions,the homogenous model based on the com...A study on the character of pressure wave propagation was proposed for the gas liquid oxygen two-phase flow in the pipe between pumps.According to the practical working conditions,the homogenous model based on the compressibility theory regarding a single bubble in an infinite liquid,and Redlich-Kwong gas equation was derived a model for the low temperature and high pressure case,especially considering the change of the ratio of density of gas to one of liquid.The numerical tests were conducted.The results not only show the agreement between numerical simulation for this model and experiment at the normal temperature and pressure is good,but also show that the modifications of the model for the low temperature and high pressure condition are necessary.The study is of reference to further study of oscillation restrain and relative pipe tests.展开更多
A series of steady and unsteady numerical calculations of the internal flow in mixed-flow pumps with three different specific speeds were carried out based on the N-S equation coupled with the standard k-εturbulence ...A series of steady and unsteady numerical calculations of the internal flow in mixed-flow pumps with three different specific speeds were carried out based on the N-S equation coupled with the standard k-εturbulence model under different operating conditions to investigate the relationship between the impeller specific speed and the pump performance as well as pressure pulsations.Meanwhile,the pump performance and pressure pulsations inside the mixed-flow pump with three different specific speeds were also analyzed and compared with the corresponding test data.From the results,the averaged deviations between the predicted and tested head among different impellers are below 5%,and with respect to the equivalent impeller specific speeds of 280 and 260,the values are 4.30%and 3.69%,respectively.For all the impeller schemes,the best efficiency point of the mixed-flow pump is found at the flow rate of 1.2 Q_(d) and the higher head deviation occurs at lower flow rates.Especially,it can be found that the specific speed has a slight effect on the pressure fluctuation in the impellers.Eventually,it is determined that the pump performance curves calculated by numerical simu-lations have good agreement with the relevant experimental results,which verifies that the numerical methods used in the present study are accurate to a certain extent.Furthermore,the results also provide some references to the pressure pulsation analysis and the performance improvement of the mixed-flow pump design.展开更多
AIM: To evaluate the effectiveness of automated irrigation pumps(AIPs) in improving the quality of the bowel preparation and the yield of colonoscopy.METHODS: A retrospective observational study was conducted at a sin...AIM: To evaluate the effectiveness of automated irrigation pumps(AIPs) in improving the quality of the bowel preparation and the yield of colonoscopy.METHODS: A retrospective observational study was conducted at a single medical center. Outpatient colonoscopies performed during a 4-mo time period when AIPs were not in use, were compared to colonoscopies performed during control period. The main outcomes measured were quality of bowel preparation, procedures aborted due to poor preparation, recommendations to repeat at short interval due to suboptimal bowel preparation and adenoma detection rates.RESULTS: One thousand and thirty-seven colonoscopies were included. A higher proportion of cases did not achieve a satisfactory bowel preparation when AIPs were not used(24.4% vs 10.3%, P < 0.01). The number of procedures aborted due to inadequate preparation was not significantly different, however a repeat procedure at a short interval was recommended in a higher proportion of cases when AIPs were not used(21.3% vs 6.9%, P < 0.01). Good or excellent preparation was 2.91(95%CI: 2.04-4.15) times more likely when AIPs were used. Detection of polyps and adenomas was not significantly different.CONCLUSION: AIP use during colonoscopy results in a higher proportion of colonic preparation rated as satisfactory, although polyp detection rate is not significantly affected. Recommendations for repeat colonoscopy at shorter interval significantly decrease with the use of AIPs. This study supports the use of the irrigation pumps in endoscopy units to improve the quality of colonoscopy.展开更多
Acinetobacter baumannii has greatly increased its degree of resistance to become multidrug resistant (MDR) over the past 30 years and is on the red line of the most widely replicated bacteria according to World Health...Acinetobacter baumannii has greatly increased its degree of resistance to become multidrug resistant (MDR) over the past 30 years and is on the red line of the most widely replicated bacteria according to World Health Organization (WHO). The efflux pumps are the main cause for the increasing antibiotic resistance of A. baumannii originated from nosocomial infection. The progressive resistance of A. baumannii even on the recent drugs (tigecycline and fosfomycin) reduces to very effective antibiotic scale. With attention focused on MDR and pan-drug-resistant (PDR) in A. baumannii multiple works on efflux pumps chemical inhibitor (NMP, PAβN, omeprazole, verapamil, reserpine, CCCP) are still in progress. Certain inhibitors from plants (Biricodar and timcodar, Falvone, Mahonia, Dalea versicolor, Lycopus europaeus, and Rosmarinus officinalis) have the capability to have such compounds according to their very significant synergistic effect with antibiotics. In this review we focused on the growth of antibiotic resistance to explain the mechanism of efflux pumps into these different super families and a comprehensive understanding of the extrusion, regulation and physiology role of drug efflux pumps in the essential development of anti-resistivity drugs. We recapitulated the evolution of the work carried out in these fields during the last years and in the course of elaboration, with the aim of increasing the chances of decreasing bacterial resistivity to antibiotics.展开更多
By analyzing the principle of dual-pump parametric amplification and the polarization dependent gain of fiber optical parametric amplifier(FOPA),a polarization-insensitive FOPA based on polarization-diversity techniqu...By analyzing the principle of dual-pump parametric amplification and the polarization dependent gain of fiber optical parametric amplifier(FOPA),a polarization-insensitive FOPA based on polarization-diversity technique with dual parallel pumps is presented.The performances of polarization-insensitivity,gain and BER are theoretically analyzed and numerically simulated by comparing the proposed scheme with parallel pump solution and orthogonal pump solution.The presented solution can reduce the complexity of state of polarization(SoP) of pumps.展开更多
Plasma membrane Ca2+pumps(PMCA)play a major role in Ca2+homeostasis and signaling by extruding cellular Ca2+with high affinity.PMCA isoforms are encoded by four genes which are expressed differentially in various cell...Plasma membrane Ca2+pumps(PMCA)play a major role in Ca2+homeostasis and signaling by extruding cellular Ca2+with high affinity.PMCA isoforms are encoded by four genes which are expressed differentially in various cell types in normal and disease states.Therefore, PMCA isoform selective inhibitors would aid in delineating their role in physiology and pathophysiology.We are testing the hypothesis that extracellular domains of PMCA can be used as allosteric targets to obtain a novel class of PMCA-specific inhibitors termed caloxins. This review presents the concepts behind the invention of caloxins and our progress in this area.A section is also devoted to the applications of caloxins in literature. We anticipate that isoform-selective caloxins will aid in understanding PMCA physiology in health and disease. With strategies to develop therapeutics from bioactive peptides,caloxins may become clinically useful in car diovascular diseases,neurological disorders,retinopathy,cancer and contraception.展开更多
Cells are equipped with mechanisms to control tightly the influx, efflux and resting level of free calcium (Ca 2+ ). Inappropriate Ca 2+ signaling and abnormal Ca 2+ levels are involved in many clinical disorders incl...Cells are equipped with mechanisms to control tightly the influx, efflux and resting level of free calcium (Ca 2+ ). Inappropriate Ca 2+ signaling and abnormal Ca 2+ levels are involved in many clinical disorders including heart disease, Alzheimer's disease and stroke. Ca 2+ also plays a major role in cell growth, differentiation and motility; disturbances in these processes underlie cell transformation and the progression of cancer. Accordingly, research in the Strehler laboratory is focused on a better understanding of the molecular "toolkit" needed to ensure proper Ca 2+ homeostasis in the cell, as well as on the mechanisms of localized Ca 2+ signaling. A longterm focus has been on the plasma membrane calcium pumps (PMCAs), which are linked to multiple disorders including hearing loss, neurodegeneration, and heart disease. Our work over the past 20 years or more has revealed a surprising complexity of PMCA isoforms with different functional characteristics, regulation, and cellular localization. Emerging evidence shows how specific PMCAs contribute not only to setting basal intracellular Ca 2+ levels, but also to local Ca 2+ signaling and vectorial Ca 2+ transport. A second major research arearevolves around the calcium sensor protein calmodulin and an enigmatic calmodulin-like protein (CALML3) that is linked to epithelial differentiation. One of the cellular targets of CALML3 is the unconventional motor protein myosin-10, which raises new questions about the role of CALML3 and myosin-10 in cell adhesion and migration in normal cell differentiation and cancer.展开更多
Condition based maintenance(CBM) is one of the solutions to machinery maintenance requirements. Latest approaches to CBM aim at reducing human engagement in the real-time fault detection and decision making. Machine l...Condition based maintenance(CBM) is one of the solutions to machinery maintenance requirements. Latest approaches to CBM aim at reducing human engagement in the real-time fault detection and decision making. Machine learning techniques like fuzzy-logic-based systems, neural networks, and support vector machines help to reduce human involvement. Most of these techniques provide fault information with 100% confidence. It is undeniably apparent that this area has a vast application scope. To facilitate future exploration, this review is presented describing the centrifugal pump faults, the signals they generate, their CBM based diagnostic schemes, and case studies for blockage and cavitation fault detection in centrifugal pump(CP) by performing the experiment on test rig. The classification accuracy is above 98% for fault detection. This review gives a head-start to new researchers in this field and identifies the un-touched areas pertaining to CP fault diagnosis.展开更多
文摘The accelerated pace of natural and human-driven climate change presents profound challenges for Earth's systems.Oceans and ice sheets are critical regulators of climate systems,functioning as carbon sinks and thermal reservoirs.However,they are increasingly vulnerable to warming and greenhouse gas emissions.
基金The authors gratefully acknowledge the filnancial support of the National Natural Science Foundation of China(Grant No.52369018)the Major Training Program of University Research and Innovation Platform of Gansu Provincial Department of Education(No.2024CXPT-09)+1 种基金the Administration of Central Funds Guiding the Local Science and Technology Development,China(Grant No.23ZYQA0320)the Double First-Class Key Program of Gansu Provincial Department of Education,Grant No.GCJ2022-38.
文摘Erosion in slurry pumps presents a persistent challenge in industrial applications.This study examines the erosion of the static components of a 150ZJ-C42 centrifugal slurry pump,currently in operation at a beneficiation plant,under varying particle conditions.Utilizing high-precision three-dimensional reverse engineering,the pump’s flow passage geometry was reconstructed to facilitate detailed erosion analysis.Focusing on the front and rear baffles of the pump chamber,as well as the volute,erosion patterns were analyzed for different particle volume concentrations and sizes.The results reveal that the highest erosion damage consistently occurs near the volute tongue,with wear being most severe in regions adjacent to the partition plate near the rear cover.Erosion damage intensity in this area correlates positively with particle diameter.Notably,the average erosion rate in the volute surpasses that of the front and rear chamber liners,reaching a value as high as 6.03×10^(-7)kg·m^(-2)·s^(-1)at a particle concentration of 9%and diameter of 0.1 mm,adversely impacting pump stability.For the pump chamber baffles,increased erosion is observed at a particle diameter of 0.05 mm under constant volume concentration conditions,while higher particle concentrations exacerbate localized erosion.
基金supported by the Technology Innovation Program(20023566,‘Development and Demonstration of Industrial IoT and AI-Based Process Facility Intelligence Support System in Small and Medium Manufacturing Sites’)funded by the Ministry of Trade,Industry,&Energy(MOTIE,Republic of Korea).
文摘Centrifugal Pumps(CPs)are critical machine components in many industries,and their efficient operation and reliable Fault Diagnosis(FD)are essential for minimizing downtime and maintenance costs.This paper introduces a novel FD method to improve both the accuracy and reliability of detecting potential faults in such pumps.Theproposed method combinesWaveletCoherent Analysis(WCA)and Stockwell Transform(S-transform)scalograms with Sobel and non-local means filters,effectively capturing complex fault signatures from vibration signals.Using Convolutional Neural Network(CNN)for feature extraction,the method transforms these scalograms into image inputs,enabling the recognition of patterns that span both time and frequency domains.The CNN extracts essential discriminative features,which are then merged and passed into a Kolmogorov-Arnold Network(KAN)classifier,ensuring precise fault identification.The proposed approach was experimentally validated on diverse datasets collected under varying conditions,demonstrating its robustness and generalizability.Achieving classification accuracy of 100%,99.86%,and 99.92%across the datasets,this method significantly outperforms traditional fault detection approaches.These results underscore the potential to enhance CP FD,providing an effective solution for predictive maintenance and improving overall system reliability.
基金Financial support from the National Natural Science Foundation of China(21736008)。
文摘Recovering waste heat is essential for primary energy savings and carbon emission reduction.To provide direct and reliable suggestions for factories to recover waste heat,energetic,economic and exergoeconomic comparison between direct heat exchange(DHE)and open-cycle mechanical heat pump(MHP)under various operating conditions is carried out in this work.The price ratios R_(ES)(electricity to steam)and R_(HS)(hot water to steam)are introduced to quantify regional impacts and conduct quantitative analysis.A semi-empirical formula is obtained to explore the exergoeconomic performance of the two systems.For waste heat within 373.15-423.15 K,the exergy efficiency of the DHE with a temperature difference of 10-90 K is always lower than that of the MHP with a temperature lift of 10-50 K.The economic performance of the two systems has a break-even point,depending on the operating parameters and relative prices of electricity,steam,and hot water.Under the average R_(ES)(3.8)in China,if R_(HS)is higher than 0.748,the annual revenue of the DHE is always higher,whereas the MHP is more economical when R_(HS)is lower than 0.110.In regions where R_(ES)is higher than 4.353,the annual revenue of the MHP will be negative in some cases.
文摘In the United Kingdom, means of meeting domestic heating is being electrified to decarbonise in effort to reduce the greenhouse gases emissions from the burning of natural gas. Therefore, the uptake of heat pumps is on the increase. The operation and working principle of heat pumps must be well understood in the investigations of their impacts on the grid and the grid assets, especially distribution transformers which could be overloaded due to higher peak load demand. This work develops an operational model of heat pumps as combined space heating and domestic hot water provider implemented in MATLAB. The developed operational model of heat pumps is adaptable and repeatable for different input parameters. The developed model is used to generate daily average demand profiles of heat pumps for a typical winter weekday and a typical summer weekday. The generated demand profiles of heat pumps by the developed model compared well with the demand profiles of heat pumps generated from actual field projects which are usually expensive and time-tasking.
基金Funding by Ministerium für Wirtschaft,Innovation,Digitalisierung und Energie des Landes Nordrhein-Westfalen。
文摘This contribution presents a novel wear dependent virtual flow rate sensor for single stage single lobe progressing cavity pumps. We study the wear-induced material loss of the pump components and the impact of this material loss on the volumetric efficiency. The results are combined with an established backflow model to implement a backflow calculation procedure that is adaptive to wear. We use a laboratory test setup with a highly abrasive fluid and operate a pump from new to worn condition to validate our approach. The obtained measurement data show that the presented virtual sensor is capable of calculating the flow rate of a pump being subject to wear during its regular operation.
基金National Key R&D Program of China(Grant No.2020YFC1512404).
文摘To investigate the influence of structural parameters on the performances and internal flow characteristics of partial flow pumps at a low specific speed of 10000 rpm,special attention was paid to the first and second stage impeller guide vanes.Moreover,the impeller blade outlet width,impeller inlet diameter,blade inclination angle,and number of blades were considered for orthogonal tests.Accordingly,nine groups of design solutions were formed,and then used as a basis for the execution of numerical simulations(CFD)aimed at obtaining the efficiency values and heads for each design solution group.The influence of impeller geometric parameters on the efficiency and head was explored,and the“weight”of each factor was obtained via a range analysis.Optimal structural parameters were finally chosen on the basis of the numerical simulation results,and the performances of the optimized model were verified accordingly(yet by means of CFD).Evidence is provided that the increase in the efficiency and head of the optimized model was 12.11%and 23.5 m,respectively,compared with those of the original model.
基金co-supported by the National Natural Science Foundation of China(No.51775500 and 51675482)the Open Found of the State Key Laboratory of Fluid Power and Mechatronic Systems of China(No.GZKF-201822)。
文摘Aviation fuel pumps of the future are required to be highly efficient and lightweight.As such,this work presents the designs of various mechanisms and structures of advanced twodimensional piston pumps for aero-engines,and their universal kinematic design methods are detailed herein.The efficiency of various piston pump prototypes was experimentally tested at various speeds in an open circuit.The experimental results indicate that two-dimensional piston pumps have a volumetric efficiency>91%and a higher power–mass ratio than conventional fuel pumps under all the conditions studied.Furthermore,the structural and material problems encountered during testing can provide a blueprint for further improvement of the design and processing of two-dimensional piston fuel pumps.
基金Supported by Research and Innovation Project for College Graduates of Jiangsu Province of China(Grant No.CXZZ13_0673)National Natural Science Foundation of China(Grant No.51009072)+1 种基金National Science&Technology Pillar Program of China(Grant No.2011BAF14B04)State Key Program of National Natural Science Foundation of China(Grant No.51239005)
文摘With the increasing noise pollution, low noise optimization of centrifugal pimps has become a hot topic. However, experimental study on this problem is unacceptable for industrial applications due to unsustainable cost. A hybrid method that couples computational fluid dynamics （CFD） with computational aeroacoustic software is used to predict the flow-induced noise of pumps in order to minimize the noise of centrifugal pumps in actual projects. Under Langthjem＇s assumption that the blade surface pressure is the main flow-induced acoustic source in centrifugal pumps, the blade surface pressure pulsation is considered in terms of the acoustical sources and simulated using CFX software. The pressure pulsation and noise distribution in the near-cutoff region are examined for the blade-passing frequency （BPF） noise, and the sound pressure level （SPL） reached peaks near the cutoff that corresponded with the pressure pulsation in this region. An experiment is performed to validate this prediction. Four hydrophones are fixed to the inlet and outlet ports of the test pump to measure the flow-induced noise from the four-port model. The simulation results for the noise are analyzed and compared with the experimental results. The variation in the calculated noise with changes in the flow agreed well with the experimental results. When the flow rate was increased, the SPL first decreased and reached the minimum near the best efficient point （BEP）; it then increased when the flow rate was further increased. The numerical and experimental results confirmed that the BPF noise generated by a blade-rotating dipole roughly reflects the acoustic features of centrifugal pumps. The noise simulation method in current study has a good feasibility and suitability, which could be adopted in engineering design to predict and optimize the hydroacoustic behavior of centrifugal pumps.
基金National Natural Science Foundation of China(Grant No.52005429)Open Foundation of State Key Laboratory of Fluid Power and Mechatronic Systems of China(Grant No.GZKF-201911)National Key Research and Development Program of China(Grant No.2018YFB2000703).
文摘Raising the rotational speed of an axial piston pump is useful for improving its power density;however,the churning losses of the piston increase significantly with increasing speed,and this reduces the performance and efficiency of the axial piston pump.Currently,there has been some research on the churning losses of pistons;however,it has rarely been analyzed from the perspective of the piston number.To improve the performance and efficiency of the axial piston pump,a computational fluid dynamics(CFD)simulation model of the churning loss was established,and the effect of piston number on the churning loss was studied in detail.The simulation analysis results revealed that the churning losses initially increased as the number of pistons increased;however,when the number of pistons increased from six to nine,the torque of the churning losses decreased because of the hydrodynamic shadowing effect.In addition,in the analysis of cavitation results,it was determined that the cavitation area of the axial piston pump was mainly concentrated around the piston,and the cavitation became increasingly severe as the speed increased.By comparing the simulation results with and without the cavitation model,it was observed that the cavitation phenomenon is beneficial for the reduction of churning losses.In this study,a piston churning loss test rig that can eliminate other friction losses was established to verify the accuracy of the simulation results.A comparative analysis indicated that the simulation results were consistent with the actual situation.In addition,this study also conducted a simulation study on seven and nine piston pumps with the same displacement.The simulation results revealed that churning losses of the seven pistons were generally greater than those of the nine pistons under the same displacement.In addition,regarding the same piston number and displacement,reducing the pitch circle radius of piston bores is effective in reducing the churning loss.This research analyzes the effect of piston number on the churning loss,which has certain guiding significance for the structural design and model selection of axial piston pumps.
基金Supported by National Natural Science Foundation of China(Grant Nos.51809121,51879121)China Postdoctoral Science Foundation(Grant No.2021M701535).
文摘The momentum flow exchange between the impeller and side channel produces highly turbulent flows in side channel pumps.The turbulent flows feature complex patterns of vortex structures that are partly responsible for the dissipation of energy losses and unsteady pressure pulsations.The concept of turbulent flows in side channel pumps requires a reliable vortex identification criterion to capture and predict the effects of the vortex structures on the performance.For this reason,the current study presents the application of the new Ω-criterion to a side channel pump model in comparison with other traditional methods such as Qand λ2 criteria.The 3D flow fields of the pump were obtained through unsteady Reynolds-averaged Navier-Stokes(RANS)simulations.Comparative studies showed that the Ω-criterion identifies the vortex of different intensities with a standard threshold,Ω=0.52.The Q and λ2 criteria required different thresholds to capture vortex of different intensities thus leads to subjective errors.Comparing theΩ-criterion intensity on different planes with the entropy losses and pressure pulsation,the longitudinal vortex plays an important role in the momentum exchange development which increases the head performance of the pump.However,the rate of exchange is impeded by the axial and radial vortices restricted in the impeller.Therefore,the impeller generates the highest entropy loss and pressure pulsation intensities which lower the output efficiency.Finally,the findings provide a fundamental background to the morphology of the vortex structures in the turbulent flows which can be dependent upon for efficiency improvement of side channel pumps.
文摘An overview of some popular rotary and reciprocating positive displacement( PD) pump types is given with the objective of presenting and comparing the respective sizing relationships and performance features. Reciprocating pumps discussed are the piston and plunger types. Rotary pumps addressed are gear( external and internal),vane,lobe,screw,and liquid ring pumps. To put the relative pump sizes in perspective,attention is fixed on the rotors or reciprocating elements of PD pumps,just as impellers indicate the sizes of rotodynamic pumps. The size of a PD pump is found from a dimensionless combination of displacement flow rate,rotative speed and diameter. The flow rate,head( or pressure rise) and power are related through the component efficiencies. The cavitation coefficient,often close to unity,connects the rotor tip speed or piston speed with the required NPSH,which can also be affected by the pressure rise of the pump due to leakage across the internal clearances. Operational effects due to cavitation,ingestion of gas or abrasives,and viscous and non-Newtonian fluids are discussed.
文摘A study on the character of pressure wave propagation was proposed for the gas liquid oxygen two-phase flow in the pipe between pumps.According to the practical working conditions,the homogenous model based on the compressibility theory regarding a single bubble in an infinite liquid,and Redlich-Kwong gas equation was derived a model for the low temperature and high pressure case,especially considering the change of the ratio of density of gas to one of liquid.The numerical tests were conducted.The results not only show the agreement between numerical simulation for this model and experiment at the normal temperature and pressure is good,but also show that the modifications of the model for the low temperature and high pressure condition are necessary.The study is of reference to further study of oscillation restrain and relative pipe tests.
基金National Natural Science Foundation of China(51976078)Senior Personnel Scientific Research Foundation of Jiangsu University:(15JDG073)Open Research Subject of Key Laboratory of Fluid and Power Machinery,Ministry of Education(szjj2016-065)。
文摘A series of steady and unsteady numerical calculations of the internal flow in mixed-flow pumps with three different specific speeds were carried out based on the N-S equation coupled with the standard k-εturbulence model under different operating conditions to investigate the relationship between the impeller specific speed and the pump performance as well as pressure pulsations.Meanwhile,the pump performance and pressure pulsations inside the mixed-flow pump with three different specific speeds were also analyzed and compared with the corresponding test data.From the results,the averaged deviations between the predicted and tested head among different impellers are below 5%,and with respect to the equivalent impeller specific speeds of 280 and 260,the values are 4.30%and 3.69%,respectively.For all the impeller schemes,the best efficiency point of the mixed-flow pump is found at the flow rate of 1.2 Q_(d) and the higher head deviation occurs at lower flow rates.Especially,it can be found that the specific speed has a slight effect on the pressure fluctuation in the impellers.Eventually,it is determined that the pump performance curves calculated by numerical simu-lations have good agreement with the relevant experimental results,which verifies that the numerical methods used in the present study are accurate to a certain extent.Furthermore,the results also provide some references to the pressure pulsation analysis and the performance improvement of the mixed-flow pump design.
基金Supported by Resources and the use of facilities at the John D.Dingell VA Medical CenterDetroit+1 种基金MIUnited States(the views expressed in this article are those of the authors and do not represent those of the Department of Veterans Affairs or the United States Government)
文摘AIM: To evaluate the effectiveness of automated irrigation pumps(AIPs) in improving the quality of the bowel preparation and the yield of colonoscopy.METHODS: A retrospective observational study was conducted at a single medical center. Outpatient colonoscopies performed during a 4-mo time period when AIPs were not in use, were compared to colonoscopies performed during control period. The main outcomes measured were quality of bowel preparation, procedures aborted due to poor preparation, recommendations to repeat at short interval due to suboptimal bowel preparation and adenoma detection rates.RESULTS: One thousand and thirty-seven colonoscopies were included. A higher proportion of cases did not achieve a satisfactory bowel preparation when AIPs were not used(24.4% vs 10.3%, P < 0.01). The number of procedures aborted due to inadequate preparation was not significantly different, however a repeat procedure at a short interval was recommended in a higher proportion of cases when AIPs were not used(21.3% vs 6.9%, P < 0.01). Good or excellent preparation was 2.91(95%CI: 2.04-4.15) times more likely when AIPs were used. Detection of polyps and adenomas was not significantly different.CONCLUSION: AIP use during colonoscopy results in a higher proportion of colonic preparation rated as satisfactory, although polyp detection rate is not significantly affected. Recommendations for repeat colonoscopy at shorter interval significantly decrease with the use of AIPs. This study supports the use of the irrigation pumps in endoscopy units to improve the quality of colonoscopy.
文摘Acinetobacter baumannii has greatly increased its degree of resistance to become multidrug resistant (MDR) over the past 30 years and is on the red line of the most widely replicated bacteria according to World Health Organization (WHO). The efflux pumps are the main cause for the increasing antibiotic resistance of A. baumannii originated from nosocomial infection. The progressive resistance of A. baumannii even on the recent drugs (tigecycline and fosfomycin) reduces to very effective antibiotic scale. With attention focused on MDR and pan-drug-resistant (PDR) in A. baumannii multiple works on efflux pumps chemical inhibitor (NMP, PAβN, omeprazole, verapamil, reserpine, CCCP) are still in progress. Certain inhibitors from plants (Biricodar and timcodar, Falvone, Mahonia, Dalea versicolor, Lycopus europaeus, and Rosmarinus officinalis) have the capability to have such compounds according to their very significant synergistic effect with antibiotics. In this review we focused on the growth of antibiotic resistance to explain the mechanism of efflux pumps into these different super families and a comprehensive understanding of the extrusion, regulation and physiology role of drug efflux pumps in the essential development of anti-resistivity drugs. We recapitulated the evolution of the work carried out in these fields during the last years and in the course of elaboration, with the aim of increasing the chances of decreasing bacterial resistivity to antibiotics.
基金supported by the National Basic Research Program of China (2010CB328304)
文摘By analyzing the principle of dual-pump parametric amplification and the polarization dependent gain of fiber optical parametric amplifier(FOPA),a polarization-insensitive FOPA based on polarization-diversity technique with dual parallel pumps is presented.The performances of polarization-insensitivity,gain and BER are theoretically analyzed and numerically simulated by comparing the proposed scheme with parallel pump solution and orthogonal pump solution.The presented solution can reduce the complexity of state of polarization(SoP) of pumps.
基金Supported by Grant-in-Aid from the Heart and Stroke Foundation of Ontario and a Doctoral Award to MMS from the Heartand Stroke Foundation of CanadaThis work is part of a pendingpatent and US Patent 7091174B2
文摘Plasma membrane Ca2+pumps(PMCA)play a major role in Ca2+homeostasis and signaling by extruding cellular Ca2+with high affinity.PMCA isoforms are encoded by four genes which are expressed differentially in various cell types in normal and disease states.Therefore, PMCA isoform selective inhibitors would aid in delineating their role in physiology and pathophysiology.We are testing the hypothesis that extracellular domains of PMCA can be used as allosteric targets to obtain a novel class of PMCA-specific inhibitors termed caloxins. This review presents the concepts behind the invention of caloxins and our progress in this area.A section is also devoted to the applications of caloxins in literature. We anticipate that isoform-selective caloxins will aid in understanding PMCA physiology in health and disease. With strategies to develop therapeutics from bioactive peptides,caloxins may become clinically useful in car diovascular diseases,neurological disorders,retinopathy,cancer and contraception.
基金Supported by The National Institutes of Health (NS51769)the Mayo Foundation for Education and Research
文摘Cells are equipped with mechanisms to control tightly the influx, efflux and resting level of free calcium (Ca 2+ ). Inappropriate Ca 2+ signaling and abnormal Ca 2+ levels are involved in many clinical disorders including heart disease, Alzheimer's disease and stroke. Ca 2+ also plays a major role in cell growth, differentiation and motility; disturbances in these processes underlie cell transformation and the progression of cancer. Accordingly, research in the Strehler laboratory is focused on a better understanding of the molecular "toolkit" needed to ensure proper Ca 2+ homeostasis in the cell, as well as on the mechanisms of localized Ca 2+ signaling. A longterm focus has been on the plasma membrane calcium pumps (PMCAs), which are linked to multiple disorders including hearing loss, neurodegeneration, and heart disease. Our work over the past 20 years or more has revealed a surprising complexity of PMCA isoforms with different functional characteristics, regulation, and cellular localization. Emerging evidence shows how specific PMCAs contribute not only to setting basal intracellular Ca 2+ levels, but also to local Ca 2+ signaling and vectorial Ca 2+ transport. A second major research arearevolves around the calcium sensor protein calmodulin and an enigmatic calmodulin-like protein (CALML3) that is linked to epithelial differentiation. One of the cellular targets of CALML3 is the unconventional motor protein myosin-10, which raises new questions about the role of CALML3 and myosin-10 in cell adhesion and migration in normal cell differentiation and cancer.
文摘Condition based maintenance(CBM) is one of the solutions to machinery maintenance requirements. Latest approaches to CBM aim at reducing human engagement in the real-time fault detection and decision making. Machine learning techniques like fuzzy-logic-based systems, neural networks, and support vector machines help to reduce human involvement. Most of these techniques provide fault information with 100% confidence. It is undeniably apparent that this area has a vast application scope. To facilitate future exploration, this review is presented describing the centrifugal pump faults, the signals they generate, their CBM based diagnostic schemes, and case studies for blockage and cavitation fault detection in centrifugal pump(CP) by performing the experiment on test rig. The classification accuracy is above 98% for fault detection. This review gives a head-start to new researchers in this field and identifies the un-touched areas pertaining to CP fault diagnosis.
