In this article we modify our previous model for the mechanisms underlying the glitch phenomena in pulsars. Accordingly, pulsars are born with embryonic cores that are made of purely incompressible superconducting glu...In this article we modify our previous model for the mechanisms underlying the glitch phenomena in pulsars. Accordingly, pulsars are born with embryonic cores that are made of purely incompressible superconducting gluon-quark superfluid (henceforth SuSu-cores). As the ambient medium cools and spins down due to emission of magnetic dipole radiation, the mass and size of SuSu-cores must grow discretely with time, in accordance with the Onsager-Feynmann analysis of superfluidity. Here we argue that the spacetime embedding glitching pulsars is dynamical and of bimetric nature: inside SuSu-cores the spacetime must be flat, whereas the surrounding region, where the matter is compressible and dissipative, the spacetime is Schwarzschild. It is argued here that the topological change of spacetime is derived by the strong nuclear force, whose operating length scales are found to increase with time to reach O (1) cm at the end of the luminous lifetimes of pulsars. The here-presented model is in line with the recent radio- and gravitational wave observations of pulsars and merger of neutron stars.展开更多
BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for ...BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.展开更多
Megahertz-peaked spectra(MPS)pulsars are referred as cases whose radio spectra turn over around 100 MHz.We identified 53 MPS pulsars based on the spectral data from the literature,and statistically analyzed the spatia...Megahertz-peaked spectra(MPS)pulsars are referred as cases whose radio spectra turn over around 100 MHz.We identified 53 MPS pulsars based on the spectral data from the literature,and statistically analyzed the spatial location distribution,the magnetic field-period distribution,peak frequencies,spectral indices,and dispersion measures of these MPS pulsars.We found that there is a strong positive correlation between the dispersion measures and the peak frequencies of MPS pulsars,and negative correlations of the dispersion measures with spectral indices and the ages are also found.Such correlations suggest that the interstellar medium is an important factor that affects observational properties of MPS pulsars.展开更多
Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN model...Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.展开更多
Binary millisecond pulsars with a massive white dwarf(WD)companion are intermediate-mass binary pulsars(IMBPs).They are formed via the Case BB Roche-lobe overflow evolution channel if they are in compact orbits with a...Binary millisecond pulsars with a massive white dwarf(WD)companion are intermediate-mass binary pulsars(IMBPs).They are formed via the Case BB Roche-lobe overflow evolution channel if they are in compact orbits with an orbital period of less than 1 day.They are fairly rare in the known pulsar population;only five such IMBPs have been discovered before,and one of them is in a globular cluster.Here we report six IMBPs in compact orbits:PSRs J0416+5201,J0520+3722,J1919+1341,J1943+2210,J1947+2304 and J2023+2853,discovered during the Galactic Plane Pulsar Snapshot survey by using the Five-hundred-meter Aperture Spherical radio Telescope,doubling the number of such IMBPs due to the high survey sensitivity in the short survey time of 5 minutes.Follow-up timing observations show that they all have either a CO WD or an ONeMg WD companion with a mass greater than about 0.8M_(⊙)in a very circular orbit with an eccentricity in the order of10^(−5).PSR J0416+5201 should be an ONeMg WD companion with a remarkable minimum mass of 1.28M_(⊙).These massive WD companions lead to a detectable Shapiro delay for PSRs J0416+5201,J0520+3722,J1943+2210,and J2023+2853,indicating that their orbits are highly inclined.From the measurement of the Shapiro delay,the pulsar mass of J1943+2210 was constrained to be 1.84^(+0.11)_(-0.09)M_(⊙),and that of PSR J2023+2853 to be 1.28^(+0.06)_(-0.05)M_(⊙).展开更多
Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited t...Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.展开更多
The FAST radio telescope has significantly better sensitivity than any other current radio telescope.Consequently,FAST has discovered over a thousand new pulsars in sky regions already searched for 50 yr.The Galactic ...The FAST radio telescope has significantly better sensitivity than any other current radio telescope.Consequently,FAST has discovered over a thousand new pulsars in sky regions already searched for 50 yr.The Galactic Plane Pulsar Snapshot(GPPS)survey found three-quarters of these new pulsars.The article by Han et al.(2025)details the latest batch of 473 discoveries,bringing the total to 751.展开更多
The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in...The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.展开更多
Finding pulsars in binaries is important for measurements of the masses of neutron stars(NSs),for tests of gravity theories,and for studies of star evolution.We are carrying out the Galactic Plane Pulsar Snapshot surv...Finding pulsars in binaries is important for measurements of the masses of neutron stars(NSs),for tests of gravity theories,and for studies of star evolution.We are carrying out the Galactic Plane Pulsar Snapshot survey(GPPS)by using the Five-hundred-meter Aperture Spherical radio Telescope(FAST).Here we present the Keplerian parameters for 116 newly discovered pulsars in the FAST GPPS survey and obtain timing solutions for 29 pulsars.Companions of these pulsars are He white dwarfs(WDs),CO/ONe WDs,NSs,main sequence stars and ultra light objects or even planets.Our observations uncover eclipses of eight binary systems.The optical counterpart for the companion of PSR J1908+1036 is identified.The Post-Keplerian parameter w for the double NS systems PSR J0528+3529 and J1844-0128 have been measured,with which the total masses of the binary systems are determined.展开更多
The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the most sensitive telescope at the L-band(1.0-1.5 GHz)and has been used to carry out the FAST Galactic Plane Pulsar Snapshot(GPPS)survey in the last 5...The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the most sensitive telescope at the L-band(1.0-1.5 GHz)and has been used to carry out the FAST Galactic Plane Pulsar Snapshot(GPPS)survey in the last 5 yr.Up to now,the survey has covered one-fourth of the planned areas within±10o from the Galactic plane visible by FAST,and discovered 751 pulsars.After the first publication of the discovery of 201 pulsars and one rotating radio transient(RRAT)in 2021 and 76 RRATs in 2023,here we report the discovery of 473 new pulsars from the FAST GPPS survey,including 137 new millisecond pulsars and 30 new RRATs.We find 34 millisecond pulsars discovered by the GPPS survey which can be timed with a precision better than 3μs by using FAST 15 minute observations and can be used for pulsar timing arrays.The GPPS survey has discovered eight pulsars with periods greater than 10 s including one with 29.77 s.The integrated profiles of pulsars and individual pulses of RRATs are presented.During the FAST GPPS survey,we also detected previously known pulsars and updated parameters for 52 pulsars.In addition,we discovered two fast radio bursts plus one probable case with high dispersion measures indicating their extragalactic origin.展开更多
Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and neces...Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and necessity of implementing cybersecurity education for university students.Drawing on disciplinary characteristics and student learning analysis,it presents a comprehensive construction process and countermeasures for a general cybersecurity education course,covering aspects such as teaching content development,teaching resource creation,and pedagogical approaches.The aim is to provide reference and guidance for other universities in developing general cybersecurity education courses.展开更多
Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization an...Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization and modeling,on the one hand,the system has successfully achieved the reuse of software modules among different satellite models;on the other hand,it has achieved the reuse of software modules between the digital twin and the testing system,significantly improving the development efficiency of the digital twin system.The paper elaborates on the technical architecture and application fields of this digital twin system,and further prospects its future development.At the same time,through a real inorbit case,the engineering value of the digital twin system is strongly demonstrated.展开更多
The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurr...The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.展开更多
We present a polarization study of 25 globular cluster(GC)pulsars observed with the Five-hundred-meter Aperture Spherical radio Telescope(FAST),including 15 pro les measured for the rst time.The pulse width–period re...We present a polarization study of 25 globular cluster(GC)pulsars observed with the Five-hundred-meter Aperture Spherical radio Telescope(FAST),including 15 pro les measured for the rst time.The pulse width–period relationships for millisecond pulsars(MSPs)in GCs follow power-law indices of-0.268(W10)and-0.330(W50),consistent with normal pulsars.Only 20%of the sample exhibit clear S-shaped position angle curves-signi cantly fewer than in the normal pulsar population.Rotation Measures(RMs)for these pulsars suggest that GCs near the Galactic plane show higher RMs,in agreement with former studies.Polarization ratios were measured,with M53A showing the highest linear polarization(56%)and M15H the highest absolute circular polarization(37%).On average,GC pulsars exhibit lower circular(-1%)and absolute circular(11%)polarization compared to normal pulsars observed with Parkes(5%and 32%,respectively).However,their polarization distributions align with MSPs in the Galactic plane,suggesting GC environments do not drastically alter emission properties.展开更多
The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggl...The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggle with this aspect.A potential reason is that the benchmarks used for training and evaluation may not adequately offer a diverse set of transferable tasks.Although recent studies have developed bench-marking environments to address this shortcoming,they typically fall short in providing tasks that both ensure a solid foundation for generalization and exhibit significant variability.To overcome these limitations,this work introduces the concept that‘objects are composed of more fundamental components’in environment design,as implemented in the proposed environment called summon the magic(StM).This environment generates tasks where objects are derived from extensible and shareable basic components,facilitating strategy reuse and enhancing generalization.Furthermore,two new metrics,adaptation sensitivity range(ASR)and parameter correlation coefficient(PCC),are proposed to better capture and evaluate the generalization process of RL agents.Experimental results show that increasing the number of basic components of the object reduces the proximal policy optimization(PPO)agent’s training-testing gap by 60.9%(in episode reward),significantly alleviating overfitting.Additionally,linear variations in other environmental factors,such as the training monster set proportion and the total number of basic components,uniformly decrease the gap by at least 32.1%.These results highlight StM’s effectiveness in benchmarking and probing the generalization capabilities of RL algorithms.展开更多
Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—a...Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.展开更多
BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public ...BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.展开更多
Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post cont...Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.展开更多
Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the imp...Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the importance of knowledge dissemination and intervention regarding general practitioners.Methods:A total of 50 community medical staff and patients in Neijiang City were selected for a questionnaire survey conducted from April 2023 to March 2025.A self-designed questionnaire on the concepts of multimorbidity and general practitioners was employed,and the survey was carried out twice,before and after the dissemination of general practice knowledge.Based on the demographic characteristics of the participants and the differences in survey results before and after the knowledge dissemination,the influencing factors and cognitive needs of community medical staff and patients towards general practitioners at this stage were analyzed.Results:Individuals under the age of 35 acquired knowledge mainly through community education(50.00%)and electronic media(50.00%),while those aged 35-65 and over 65 primarily learned through peers,accounting for 57.14%and 48.72%,respectively.After general practice education,among individuals aged≤65,those with a college degree or higher demonstrated higher rates of multimorbidity and met the criteria for family doctor awareness compared to those aged>65 with a high school diploma or lower,with statistically significant differences(p<0.05).Logistic regression analysis revealed that educational attainment(college degree or higher)served as a protective factor for high awareness levels among general practitioners,while age(>65 years)emerged as a risk factor for high awareness levels among general practitioners,with statistically significant differences(p<0.05).Conclusion:To enhance the knowledge and awareness levels of general practitioners among community medical staff and patients,it is imperative to actively expand channels for proactive acquisition of relevant knowledge through education and outreach.Additionally,targeted educational efforts should be intensified for individuals with lower educational attainment and older age groups to establish a public awareness foundation for the effective promotion of general practitioner-led healthcare initiatives at the grassroots level.展开更多
Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,an...Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.展开更多
文摘In this article we modify our previous model for the mechanisms underlying the glitch phenomena in pulsars. Accordingly, pulsars are born with embryonic cores that are made of purely incompressible superconducting gluon-quark superfluid (henceforth SuSu-cores). As the ambient medium cools and spins down due to emission of magnetic dipole radiation, the mass and size of SuSu-cores must grow discretely with time, in accordance with the Onsager-Feynmann analysis of superfluidity. Here we argue that the spacetime embedding glitching pulsars is dynamical and of bimetric nature: inside SuSu-cores the spacetime must be flat, whereas the surrounding region, where the matter is compressible and dissipative, the spacetime is Schwarzschild. It is argued here that the topological change of spacetime is derived by the strong nuclear force, whose operating length scales are found to increase with time to reach O (1) cm at the end of the luminous lifetimes of pulsars. The here-presented model is in line with the recent radio- and gravitational wave observations of pulsars and merger of neutron stars.
文摘BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.AIM To investigate the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia.METHODS In this retrospective study,94 patients scheduled for laparoscopic minimally invasive surgery for inguinal hernia,admitted to Yiwu Central Hospital between May 2022 and May 2023,were divided into a control group(inhalation combined general anesthesia)and a treatment group(dexmedetomidine-assisted intrave-nous-inhalation combined general anesthesia).Perioperative indicators,analgesic effect,preoperative and postoperative 24-hours blood pressure(BP)and heart rate(HR),stress indicators,immune function levels,and adverse reactions were com-pared between the two groups.RESULTS Baseline data,including age,hernia location,place of residence,weight,monthly income,education level,and underlying diseases,were not significantly different between the two groups,indicating comparability(P>0.05).No significant difference was found in operation time and anesthesia time between the two groups(P>0.05).However,the treatment group exhibited a shorter postoperative urinary catheter removal time and hospital stay than the control group(P<0.05).Preoperatively,no significant differences were found in the visual analog scale(VAS)scores between the two groups(P>0.05).However,at 12,18,and 24 hours postoper-atively,the treatment group had significantly lower VAS scores than the control group(P<0.05).Although no significant differences in preoperative hemodynamic indicators were found between the two groups(P>0.05),both groups experienced some extent of changes in postoperative HR,diastolic BP(DBP),and systolic BP(SBP).Nevertheless,the treatment group showed smaller changes in HR,DBP,and SBP than the control group(P<0.05).Preoperative immune function indicators showed no significant differences between the two groups(P>0.05).However,postoperatively,the treatment group demonstrated higher levels of CD3+,CD4+,and CD4+/CD8+and lower levels of CD8+than the control group(P<0.05).The rates of adverse reactions were 6.38%and 23.40%in the treatment and control groups,respectively,revealing a significant difference(χ2=5.371,P=0.020).CONCLUSION Dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can promote early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia.It ensures stable blood flow,improves postoperative analgesic effects,reduces postoperative pain intensity,alleviates stress response,improves immune function,facilitates anesthesia recovery,and enhances safety.
基金supported in part by Chunhui plan international cooperation project of China Education Ministry under grants 202201406 and HZKY20220171.
文摘Megahertz-peaked spectra(MPS)pulsars are referred as cases whose radio spectra turn over around 100 MHz.We identified 53 MPS pulsars based on the spectral data from the literature,and statistically analyzed the spatial location distribution,the magnetic field-period distribution,peak frequencies,spectral indices,and dispersion measures of these MPS pulsars.We found that there is a strong positive correlation between the dispersion measures and the peak frequencies of MPS pulsars,and negative correlations of the dispersion measures with spectral indices and the ages are also found.Such correlations suggest that the interstellar medium is an important factor that affects observational properties of MPS pulsars.
基金funded by Centre for Advanced Modelling and Geospatial Information Systems(CAMGIS),Faculty of Engineering and IT,University of Technology Sydney.Moreover,Ongoing Research Funding Program(ORF-2025-14)King Saud University,Riyadh,Saudi Arabia,under Project ORF-2025-。
文摘Face liveness detection is essential for securing biometric authentication systems against spoofing attacks,including printed photos,replay videos,and 3D masks.This study systematically evaluates pre-trained CNN models—DenseNet201,VGG16,InceptionV3,ResNet50,VGG19,MobileNetV2,Xception,and InceptionResNetV2—leveraging transfer learning and fine-tuning to enhance liveness detection performance.The models were trained and tested on NUAA and Replay-Attack datasets,with cross-dataset generalization validated on SiW-MV2 to assess real-world adaptability.Performance was evaluated using accuracy,precision,recall,FAR,FRR,HTER,and specialized spoof detection metrics(APCER,NPCER,ACER).Fine-tuning significantly improved detection accuracy,with DenseNet201 achieving the highest performance(98.5%on NUAA,97.71%on Replay-Attack),while MobileNetV2 proved the most efficient model for real-time applications(latency:15 ms,memory usage:45 MB,energy consumption:30 mJ).A statistical significance analysis(paired t-tests,confidence intervals)validated these improvements.Cross-dataset experiments identified DenseNet201 and MobileNetV2 as the most generalizable architectures,with DenseNet201 achieving 86.4%accuracy on Replay-Attack when trained on NUAA,demonstrating robust feature extraction and adaptability.In contrast,ResNet50 showed lower generalization capabilities,struggling with dataset variability and complex spoofing attacks.These findings suggest that MobileNetV2 is well-suited for low-power applications,while DenseNet201 is ideal for high-security environments requiring superior accuracy.This research provides a framework for improving real-time face liveness detection,enhancing biometric security,and guiding future advancements in AI-driven anti-spoofing techniques.
基金supported by the National Natural Science Foundation of China(NSFC,Grant Nos.11988101,12133004 and 11833009)the Research Program of the Chinese Academy of Sciences(grant No.QYZDJ-SSW-SLH021 and JZHKYPT-2021-06).
文摘Binary millisecond pulsars with a massive white dwarf(WD)companion are intermediate-mass binary pulsars(IMBPs).They are formed via the Case BB Roche-lobe overflow evolution channel if they are in compact orbits with an orbital period of less than 1 day.They are fairly rare in the known pulsar population;only five such IMBPs have been discovered before,and one of them is in a globular cluster.Here we report six IMBPs in compact orbits:PSRs J0416+5201,J0520+3722,J1919+1341,J1943+2210,J1947+2304 and J2023+2853,discovered during the Galactic Plane Pulsar Snapshot survey by using the Five-hundred-meter Aperture Spherical radio Telescope,doubling the number of such IMBPs due to the high survey sensitivity in the short survey time of 5 minutes.Follow-up timing observations show that they all have either a CO WD or an ONeMg WD companion with a mass greater than about 0.8M_(⊙)in a very circular orbit with an eccentricity in the order of10^(−5).PSR J0416+5201 should be an ONeMg WD companion with a remarkable minimum mass of 1.28M_(⊙).These massive WD companions lead to a detectable Shapiro delay for PSRs J0416+5201,J0520+3722,J1943+2210,and J2023+2853,indicating that their orbits are highly inclined.From the measurement of the Shapiro delay,the pulsar mass of J1943+2210 was constrained to be 1.84^(+0.11)_(-0.09)M_(⊙),and that of PSR J2023+2853 to be 1.28^(+0.06)_(-0.05)M_(⊙).
文摘Retinal blood vessel segmentation is crucial for diagnosing ocular and cardiovascular diseases.Although the introduction of U-Net in 2015 by Olaf Ronneberger significantly advanced this field,yet issues like limited training data,imbalance data distribution,and inadequate feature extraction persist,hindering both the segmentation performance and optimal model generalization.Addressing these critical issues,the DEFFA-Unet is proposed featuring an additional encoder to process domain-invariant pre-processed inputs,thereby improving both richer feature encoding and enhanced model generalization.A feature filtering fusion module is developed to ensure the precise feature filtering and robust hybrid feature fusion.In response to the task-specific need for higher precision where false positives are very costly,traditional skip connections are replaced with the attention-guided feature reconstructing fusion module.Additionally,innovative data augmentation and balancing methods are proposed to counter data scarcity and distribution imbalance,further boosting the robustness and generalization of the model.With a comprehensive suite of evaluation metrics,extensive validations on four benchmark datasets(DRIVE,CHASEDB1,STARE,and HRF)and an SLO dataset(IOSTAR),demonstrate the proposed method’s superiority over both baseline and state-of-the-art models.Particularly the proposed method significantly outperforms the compared methods in cross-validation model generalization.
文摘The FAST radio telescope has significantly better sensitivity than any other current radio telescope.Consequently,FAST has discovered over a thousand new pulsars in sky regions already searched for 50 yr.The Galactic Plane Pulsar Snapshot(GPPS)survey found three-quarters of these new pulsars.The article by Han et al.(2025)details the latest batch of 473 discoveries,bringing the total to 751.
文摘The US 2024 general election ended with the Republican Party winning the presidential, House and Senate elections at the same time. In the presidential election, the Republican Party not only won more popular votes in over 90% counties than in the 2020 general election, but also won seven highly contested swing States with greater edges. This also marks the first time since 2004 that the Republican Party has won a relative majority of popular votes in the presidential election.
基金supported by the National SKA program of China(No.2020SKA0120200)the National Natural Science Foundation of China(No.12133004)+1 种基金the Chinese Academy of Science(No.JZHKYPT-2021-06)and the National Key R&D Program of China(No.2021YFA1600401 and 2021YFA1600400)supported by the National Natural Science Foundation of China(No.11988101,12133004 and 11833009).
文摘Finding pulsars in binaries is important for measurements of the masses of neutron stars(NSs),for tests of gravity theories,and for studies of star evolution.We are carrying out the Galactic Plane Pulsar Snapshot survey(GPPS)by using the Five-hundred-meter Aperture Spherical radio Telescope(FAST).Here we present the Keplerian parameters for 116 newly discovered pulsars in the FAST GPPS survey and obtain timing solutions for 29 pulsars.Companions of these pulsars are He white dwarfs(WDs),CO/ONe WDs,NSs,main sequence stars and ultra light objects or even planets.Our observations uncover eclipses of eight binary systems.The optical counterpart for the companion of PSR J1908+1036 is identified.The Post-Keplerian parameter w for the double NS systems PSR J0528+3529 and J1844-0128 have been measured,with which the total masses of the binary systems are determined.
基金supported by the National Natural Science Foundation of China(NSFC,Grant Nos.11988101,12133004 and 11833009)also the National SKA Program of China 2020SKA0120100The pulsar searching team is specially supported by the Chinese Academy of Sciences via the project JZHKYPT-2021-06.
文摘The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the most sensitive telescope at the L-band(1.0-1.5 GHz)and has been used to carry out the FAST Galactic Plane Pulsar Snapshot(GPPS)survey in the last 5 yr.Up to now,the survey has covered one-fourth of the planned areas within±10o from the Galactic plane visible by FAST,and discovered 751 pulsars.After the first publication of the discovery of 201 pulsars and one rotating radio transient(RRAT)in 2021 and 76 RRATs in 2023,here we report the discovery of 473 new pulsars from the FAST GPPS survey,including 137 new millisecond pulsars and 30 new RRATs.We find 34 millisecond pulsars discovered by the GPPS survey which can be timed with a precision better than 3μs by using FAST 15 minute observations and can be used for pulsar timing arrays.The GPPS survey has discovered eight pulsars with periods greater than 10 s including one with 29.77 s.The integrated profiles of pulsars and individual pulses of RRATs are presented.During the FAST GPPS survey,we also detected previously known pulsars and updated parameters for 52 pulsars.In addition,we discovered two fast radio bursts plus one probable case with high dispersion measures indicating their extragalactic origin.
基金supported in part by the 2024 Core General Education Course Construction Project of Beijing Union University,titled“Cybersecurity:Exploring the World of White Hat Hackers”the 2025 Educational Science Research Project of Beijing Union University(JK202514)+1 种基金the General Project of Science and Technology Program of Beijing Municipal Education Commission under Grant KM201911417011the Academic Research Projects of Beijing Union University(ZK30202407).
文摘Strengthening cybersecurity education for college students holds significant importance in achieving the strategic goal of building China into a cyber power.This article begins by discussing the significance and necessity of implementing cybersecurity education for university students.Drawing on disciplinary characteristics and student learning analysis,it presents a comprehensive construction process and countermeasures for a general cybersecurity education course,covering aspects such as teaching content development,teaching resource creation,and pedagogical approaches.The aim is to provide reference and guidance for other universities in developing general cybersecurity education courses.
文摘Digital twin shows broad application prospects in the aerospace field.This paper introduces a generalized satellite digital twin system in detail.With the innovative design concepts of modularization,generalization and modeling,on the one hand,the system has successfully achieved the reuse of software modules among different satellite models;on the other hand,it has achieved the reuse of software modules between the digital twin and the testing system,significantly improving the development efficiency of the digital twin system.The paper elaborates on the technical architecture and application fields of this digital twin system,and further prospects its future development.At the same time,through a real inorbit case,the engineering value of the digital twin system is strongly demonstrated.
基金supported by the Shandong Provincial Natural Science Foundation(ZR2022QH144).
文摘The phenomenon of fear memory generalization can be defined as the expansion of an individual's originally specific fear responses to a similar yet genuinely harmless stimulus or situation subsequent to the occurrence of a traumatic event[1].Fear generalization within the normal range represents an adaptive evolutionary mechanism to facilitate prompt reactions to potential threats and to enhance the likelihood of survival.
基金supported by the National Key R&D Program of China,No.2022YFC2205202the National Natural Science Foundation of China(NSFC)under grant Nos.12173052,U2031119,11773041 and 11703047+2 种基金supported by the Youth Innovation Promotion Association of the Chinese Academy of Sciences(CAS)(id.Y2022027)the CAS“Light of West China”Programthe CAS President’s International Fellowship Initiative(grant No.2021FSM0004).
文摘We present a polarization study of 25 globular cluster(GC)pulsars observed with the Five-hundred-meter Aperture Spherical radio Telescope(FAST),including 15 pro les measured for the rst time.The pulse width–period relationships for millisecond pulsars(MSPs)in GCs follow power-law indices of-0.268(W10)and-0.330(W50),consistent with normal pulsars.Only 20%of the sample exhibit clear S-shaped position angle curves-signi cantly fewer than in the normal pulsar population.Rotation Measures(RMs)for these pulsars suggest that GCs near the Galactic plane show higher RMs,in agreement with former studies.Polarization ratios were measured,with M53A showing the highest linear polarization(56%)and M15H the highest absolute circular polarization(37%).On average,GC pulsars exhibit lower circular(-1%)and absolute circular(11%)polarization compared to normal pulsars observed with Parkes(5%and 32%,respectively).However,their polarization distributions align with MSPs in the Galactic plane,suggesting GC environments do not drastically alter emission properties.
基金Supported by the National Key R&D Program of China(No.2023YFB4502200)the National Natural Science Foundation of China(No.U22A2028,61925208,62222214,62341411,62102398,62102399,U20A20227,62302478,62302482,62302483,62302480,62302481)+2 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0660300,XDB0660301,XDB0660302)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(No.YSBR-029)the Youth Innovation Promotion Association of Chinese Academy of Sciences and Xplore Prize.
文摘The challenge of enhancing the generalization capacity of reinforcement learning(RL)agents remains a formidable obstacle.Existing RL methods,despite achieving superhuman performance on certain benchmarks,often struggle with this aspect.A potential reason is that the benchmarks used for training and evaluation may not adequately offer a diverse set of transferable tasks.Although recent studies have developed bench-marking environments to address this shortcoming,they typically fall short in providing tasks that both ensure a solid foundation for generalization and exhibit significant variability.To overcome these limitations,this work introduces the concept that‘objects are composed of more fundamental components’in environment design,as implemented in the proposed environment called summon the magic(StM).This environment generates tasks where objects are derived from extensible and shareable basic components,facilitating strategy reuse and enhancing generalization.Furthermore,two new metrics,adaptation sensitivity range(ASR)and parameter correlation coefficient(PCC),are proposed to better capture and evaluate the generalization process of RL agents.Experimental results show that increasing the number of basic components of the object reduces the proximal policy optimization(PPO)agent’s training-testing gap by 60.9%(in episode reward),significantly alleviating overfitting.Additionally,linear variations in other environmental factors,such as the training monster set proportion and the total number of basic components,uniformly decrease the gap by at least 32.1%.These results highlight StM’s effectiveness in benchmarking and probing the generalization capabilities of RL algorithms.
文摘Mingalarpar!On behalf of the Consulate-General of the Republic of the Union of Myanmar in Nanning,I would like to express my sincerest congratulations to CAEXPO on reaching the remarkable milestone of over 20 years—an incredible journey filled with numerous achievements.
文摘BACKGROUND The coronavirus disease 2019(COVID-19)outbreak lasted several months,having started in December 2019.This study aimed to report the impacts of various factors on the depression levels of the general public and ascertain how emotional measures could be affected by psychosocial factors during the COVID-19 pandemic.AIM To investigate the depression levels of the general public in China during the COVID-19 pandemic.METHODS A total of 2001 self-reported questionnaires about Beck Depression Inventory(BDI)were collected on August 22,2022 via the website.Each questionnaire included four levels of depression and other demographic information.The BDI scores and incidences of different depression levels were compared between various groups of respondents.χ2 analysis and the two-tailed t-test were used to assess categorical and continuous data,respectively.Multiple linear regressions and logistic regressions were employed for correlation analysis.RESULTS The averaged BDI score in this study was higher than that for the non-epidemic periods,as reported in previous studies.Even higher BDI scores and incidences of moderate and severe depression were recorded for people who were quarantined for suspected COVID-19 infection,compared to the respondents who were not quarantined.The participants who did not take protective measures were associated with higher BDI scores than those who made efforts to keep themselves relatively safer.Similarly,the people who did not return to work had higher BDI scores compared to those managed to.A significant association existed between the depression levels of the subgroups and each of the factors,except gender and location of residence.However,quarantine was the most relative predictor for depression levels,followed by failure to take preventive measures and losing a partner,either through divorce or death.CONCLUSION Based on these data,psychological interventions for the various subpopulations in the general public can be implemented during and after the COVID-19 pandemic.Other countries can also use the data as a reference.
基金funded by Sirjan Medical Sciences Faculty,Sirjan,Iran.(Project code:402000018).
文摘Objective:The study aimed to investigate the effect of relaxation techniques in reducing fear and anxiety in patients in need of general surgery.Materials and Methods:This quasi-experimental study with a pre-post control group design was conducted on 120 patients requiring general surgery at Saman Al-Hojjaj Hospital in Sirjan County.Patients were selected using convenience sampling and randomly assigned to the intervention group(n=60)and control group(n=60).The intervention group was taught box breathing and progressive muscle relaxation techniques by a senior psychiatric nursing expert for 15-20 min every 4 h until surgery.The control group received routine care for surgery.Data on fear and anxiety outcomes were collected using the Spielberger State-Trait Anxiety Inventory and the Surgical Fear Questionnaire.Results:The intervention group had a mean total fear score of 29.27±12.69 compared to 37.20±16.39 in the control group(P=0.012),with significant reductions in both short-term(13.57±5.93 vs.15.98±8.90;P=0.209,Cohen’s d=0.32)and long-term(15.70±7.19 vs.21.22±9.11;P=0.001,Cohen’s d=0.66)fear components(total fear:P=0.012,Cohen’s d=0.54).The total anxiety score was 91.88±6.28 in the control group and 93.60±3.62 in the intervention group,with trait anxiety significantly reduced in the intervention group(P=0.039,Cohen’s d=0.41)postintervention,but no significant change in state anxiety(P=0.577,Cohen’s d=0.16).Conclusions:Relaxation techniques significantly alleviate preoperative psychological distress,effectively reducing fear and anxiety in general surgery patients.These cost-effective,non-invasive methods enhance recovery and reduce healthcare costs.We recommend training healthcare providers to implement these techniques for optimal patient outcomes.
文摘Objective:This study aims to investigate the cognitive status of community medical staff and patients in Neijiang City towards general practitioners,and analyze the current cognitive status,cognitive needs,and the importance of knowledge dissemination and intervention regarding general practitioners.Methods:A total of 50 community medical staff and patients in Neijiang City were selected for a questionnaire survey conducted from April 2023 to March 2025.A self-designed questionnaire on the concepts of multimorbidity and general practitioners was employed,and the survey was carried out twice,before and after the dissemination of general practice knowledge.Based on the demographic characteristics of the participants and the differences in survey results before and after the knowledge dissemination,the influencing factors and cognitive needs of community medical staff and patients towards general practitioners at this stage were analyzed.Results:Individuals under the age of 35 acquired knowledge mainly through community education(50.00%)and electronic media(50.00%),while those aged 35-65 and over 65 primarily learned through peers,accounting for 57.14%and 48.72%,respectively.After general practice education,among individuals aged≤65,those with a college degree or higher demonstrated higher rates of multimorbidity and met the criteria for family doctor awareness compared to those aged>65 with a high school diploma or lower,with statistically significant differences(p<0.05).Logistic regression analysis revealed that educational attainment(college degree or higher)served as a protective factor for high awareness levels among general practitioners,while age(>65 years)emerged as a risk factor for high awareness levels among general practitioners,with statistically significant differences(p<0.05).Conclusion:To enhance the knowledge and awareness levels of general practitioners among community medical staff and patients,it is imperative to actively expand channels for proactive acquisition of relevant knowledge through education and outreach.Additionally,targeted educational efforts should be intensified for individuals with lower educational attainment and older age groups to establish a public awareness foundation for the effective promotion of general practitioner-led healthcare initiatives at the grassroots level.
文摘Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.
