BACKGROUND Patients who undergo radical cervical cancer surgery often experience sexual dysfunction and psychological distress,which seriously affects their quality of life.This study aimed to evaluate the clinical ef...BACKGROUND Patients who undergo radical cervical cancer surgery often experience sexual dysfunction and psychological distress,which seriously affects their quality of life.This study aimed to evaluate the clinical effectiveness of mindfulness-based stress reduction(MBSR)therapy for psychosexual adaptation in patients after radical cervical cancer surgery.AIM To systematically evaluate the clinical effectiveness of MBSR therapy on psychosexual adaptation in patients following radical cervical cancer surgery.METHODS A multicenter retrospective study design was used to analyze the clinical data of 280 patients who underwent radical cervical cancer surgery between January 2021 and August 2024 at Lishui Central Hospital,The Fifth Hospital Affiliated to Wenzhou Medical University,Lishui Hospital of Zhejiang University and Wenzhou Central Hospital.Patients were divided into an intervention group(n=140;receiving standard MBSR intervention)and a control group(n=140;receiving only routine care and sexual health guidance).Among these,140 cases were collected from Lishui Central Hospital,The Fifth Hospital Affiliated to Wenzhou Medical University,Lishui Hospital of Zhejiang University(70 in the intervention group and 70 in the control group)and Wenzhou Central Hospital(70 in the intervention group and 70 in the control group).RESULTS After intervention,patients in the MBSR intervention group showed significant improvement in anxiety and depression levels(anxiety:5.8±1.2 vs 8.3±1.7,P<0.001;depression:6.2±1.4 vs 9.1±1.8,P<0.001).The proportion of patients with clinically significant anxiety decreased from 69.3%to 21.4%(control group:67.9%-52.9%,P<0.001).The intervention group showed significantly better Female Sexual Function Index total scores(23.5±3.6 vs 17.8±3.2,P<0.001)and scores in all dimensions than the control group,with a significantly lower incidence of sexual dysfunction(42.9%vs 67.9%,P<0.001).Regarding sexual relationship satisfaction,both patients in the intervention group(78.3±6.5 vs 65.2±7.8,P<0.001)and their partners(76.9±7.1 vs 63.6±8.3,P<0.001)showed significantly improved scores.Age-stratified analysis showed that MBSR was most effective in younger patients(≤45 years,46-55 years;P<0.001),with relatively less benefit in older patients(>55 years;P=0.032).Multivariate regression analysis confirmed that MBSR intervention[odds ratios(OR)=2.86,95%confidence interval(95%CI):1.75-4.68,P<0.001]and partner support(OR=1.92,95%CI:1.28-2.87,P=0.002)were independent positive predictive factors for improving patients'psychosexual adaptation.CONCLUSION MBSR therapy can effectively improve anxiety and depression in patients after radical cervical cancer surgery and significantly enhance sexual function and sexual relationship satisfaction,with the effects being more pronounced in younger patients.This study demonstrated that MBSR,as an integrative intervention approach,has independent positive effects on psychosexual adaptation in post-operative cervical cancer patients and is worthy of promotion in clinical practice.展开更多
The aim of this study was to compare the long-term postoperative status of hypospadiac patients by analysing their sexual psychology, sexual behaviour, sexual function and influencing factors. A total of 130 hypospadi...The aim of this study was to compare the long-term postoperative status of hypospadiac patients by analysing their sexual psychology, sexual behaviour, sexual function and influencing factors. A total of 130 hypospadiac patients hospitalized between January 1988 and December 2007 were followed up with questionnaires using Zung＇s Self-rating Depression Scale （SDS）, Self-rating Anxiety Scale （SAS）, a self-designed sexual function questionnaire and a 5-item version of the International Index of Erectile Function （IIEF-5）. The surveys served to evaluate the effects of hypospadias type, number of operations and surgical procedures on sexual psychology, sexual behaviour and sexual function. The control group consisted of 50 healthy adults. The postoperative SDS / SAS scores and occurrences of depression/anxiety in hypospadiac patients were significantly higher than those of normal controls （P 〈 0.001）. Patients with proximal hypospadias and multiple procedures differed from those with distal hypospadias and a single procedure in all parameters of sexual psychology （P 〈 0.05）. The average penile lengths and circumferences ofhypospadiac patients under either erect or flaccid conditions were significantly shorter than those of normal controls （P 〈 0.001）. A similar difference existed between patients with distal and proximal hypospadias （P 〈 0.01）. There was no significant difference in any parameter of sexual function between patients with different numbers of operations and surgical procedures. Hypospadiac patients were clearly impaired in sexual psychology and penile development. The severity of hypospadias and number of operations were key factors that influenced the sexual psychology of patients. This finding indicated the importance of long-term follow-up and psychological counselling for hypospadiac patients postoperatively.展开更多
文摘BACKGROUND Patients who undergo radical cervical cancer surgery often experience sexual dysfunction and psychological distress,which seriously affects their quality of life.This study aimed to evaluate the clinical effectiveness of mindfulness-based stress reduction(MBSR)therapy for psychosexual adaptation in patients after radical cervical cancer surgery.AIM To systematically evaluate the clinical effectiveness of MBSR therapy on psychosexual adaptation in patients following radical cervical cancer surgery.METHODS A multicenter retrospective study design was used to analyze the clinical data of 280 patients who underwent radical cervical cancer surgery between January 2021 and August 2024 at Lishui Central Hospital,The Fifth Hospital Affiliated to Wenzhou Medical University,Lishui Hospital of Zhejiang University and Wenzhou Central Hospital.Patients were divided into an intervention group(n=140;receiving standard MBSR intervention)and a control group(n=140;receiving only routine care and sexual health guidance).Among these,140 cases were collected from Lishui Central Hospital,The Fifth Hospital Affiliated to Wenzhou Medical University,Lishui Hospital of Zhejiang University(70 in the intervention group and 70 in the control group)and Wenzhou Central Hospital(70 in the intervention group and 70 in the control group).RESULTS After intervention,patients in the MBSR intervention group showed significant improvement in anxiety and depression levels(anxiety:5.8±1.2 vs 8.3±1.7,P<0.001;depression:6.2±1.4 vs 9.1±1.8,P<0.001).The proportion of patients with clinically significant anxiety decreased from 69.3%to 21.4%(control group:67.9%-52.9%,P<0.001).The intervention group showed significantly better Female Sexual Function Index total scores(23.5±3.6 vs 17.8±3.2,P<0.001)and scores in all dimensions than the control group,with a significantly lower incidence of sexual dysfunction(42.9%vs 67.9%,P<0.001).Regarding sexual relationship satisfaction,both patients in the intervention group(78.3±6.5 vs 65.2±7.8,P<0.001)and their partners(76.9±7.1 vs 63.6±8.3,P<0.001)showed significantly improved scores.Age-stratified analysis showed that MBSR was most effective in younger patients(≤45 years,46-55 years;P<0.001),with relatively less benefit in older patients(>55 years;P=0.032).Multivariate regression analysis confirmed that MBSR intervention[odds ratios(OR)=2.86,95%confidence interval(95%CI):1.75-4.68,P<0.001]and partner support(OR=1.92,95%CI:1.28-2.87,P=0.002)were independent positive predictive factors for improving patients'psychosexual adaptation.CONCLUSION MBSR therapy can effectively improve anxiety and depression in patients after radical cervical cancer surgery and significantly enhance sexual function and sexual relationship satisfaction,with the effects being more pronounced in younger patients.This study demonstrated that MBSR,as an integrative intervention approach,has independent positive effects on psychosexual adaptation in post-operative cervical cancer patients and is worthy of promotion in clinical practice.
文摘The aim of this study was to compare the long-term postoperative status of hypospadiac patients by analysing their sexual psychology, sexual behaviour, sexual function and influencing factors. A total of 130 hypospadiac patients hospitalized between January 1988 and December 2007 were followed up with questionnaires using Zung＇s Self-rating Depression Scale （SDS）, Self-rating Anxiety Scale （SAS）, a self-designed sexual function questionnaire and a 5-item version of the International Index of Erectile Function （IIEF-5）. The surveys served to evaluate the effects of hypospadias type, number of operations and surgical procedures on sexual psychology, sexual behaviour and sexual function. The control group consisted of 50 healthy adults. The postoperative SDS / SAS scores and occurrences of depression/anxiety in hypospadiac patients were significantly higher than those of normal controls （P 〈 0.001）. Patients with proximal hypospadias and multiple procedures differed from those with distal hypospadias and a single procedure in all parameters of sexual psychology （P 〈 0.05）. The average penile lengths and circumferences ofhypospadiac patients under either erect or flaccid conditions were significantly shorter than those of normal controls （P 〈 0.001）. A similar difference existed between patients with distal and proximal hypospadias （P 〈 0.01）. There was no significant difference in any parameter of sexual function between patients with different numbers of operations and surgical procedures. Hypospadiac patients were clearly impaired in sexual psychology and penile development. The severity of hypospadias and number of operations were key factors that influenced the sexual psychology of patients. This finding indicated the importance of long-term follow-up and psychological counselling for hypospadiac patients postoperatively.
