BACKGROUND Long-term antipsychotic therapy in psychiatric patients carries significant cardiovascular risks,including QT interval prolongation,myocardial injury,and functional impairment.Guanxinning,a traditional Chin...BACKGROUND Long-term antipsychotic therapy in psychiatric patients carries significant cardiovascular risks,including QT interval prolongation,myocardial injury,and functional impairment.Guanxinning,a traditional Chinese medicine formulation,has demonstrated cardioprotective potential in preclinical studies,but clinical evidence in this population remains limited.AIM To evaluate the cardioprotective effects of Guanxinning against antipsychotic-induced cardiac injury in long-term hospitalized psychiatric patients.METHODS A randomized,double-blind,placebo-controlled trial was conducted with 120 psychiatric inpatients receiving chronic antipsychotic therapy.Participants were allocated to:Intervention group:Conventional antipsychotics+Guanxinning tablets(0.38 g×4 tablets,ter in die);Control group:Conventional antipsychotics+identical placebo;Cardiac assessments at baseline and 12 months included:Electrocardiography(corrected QT interval),echocardiography(left ventricular ejection fraction,left ventricular end-diastolic diameter),serum biomarkers(cardiac troponin I,B-type natriuretic peptide,superoxide dismutase,malondialdehyde,high-sensitivity C-reactive protein).RESULTS Compared to controls,the Guanxinning group showed:Electrophysiological improvement:Corrected QT shortening(438±25 milliseconds vs 465±30 milliseconds,P<0.01).Functional enhancement:Left ventricular ejection fraction increase(58.5%±5.2%vs 53.8%±4.8%,P<0.05),left ventricular end-diastolic diameter reduction(49.8±3.5 mm vs 52.6±3.8 mm,P<0.05),Biochemical modulation:Reduced myocardial injury markers(cardiac troponin I:0.009 ng/mL vs 0.014 ng/mL;B-type natriuretic peptide:52 pg/mL vs 78 pg/mL,P<0.001),improved oxidative stress(superoxide dismutase:↑13.3 U/mL;malondialdehyde:↓0.9 nmol/mL,P<0.001),attenuated inflammation(high-sensitivity C-reactive protein:2.0 mg/L vs 3.2 mg/L,P<0.001).CONCLUSION Guanxinning significantly mitigates antipsychotic-induced cardiac injury in psychiatric patients,demonstrating:Normalization of electrophysiological parameters,Preservation of systolic/diastolic function,suppression of oxidative stress and inflammation.These findings support its clinical application as an adjunctive cardioprotective therapy,potentially through inhibition of myocardial apoptosis and antioxidant upregulation.展开更多
Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a prom...Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a promising solution due to their outstanding error-correction performance and low complexity.Unequal error protection(UEP)involves nonuniform error safeguarding for distinct data segments,achieving a fine balance between error resilience and resource allocation,which ultimately enhancing system performance and efficiency.In this paper,we propose a novel class of UEP rateless polar codes.The codes are designed based on matrix extension of polar codes,and elegant mapping and duplication operations are designed to achieve UEP property while preserving the overall performance of conventional polar codes.Superior UEP performance is attained without significant modifications to conventional polar codes,making it straightforward for compatibility with existing polar codes.A theoretical analysis is conducted on the block error rate and throughput efficiency performance.To the best of our knowledge,this work provides the first theoretical performance analysis of UEP rateless polar codes.Simulation results show that the proposed codes significantly outperform existing polar coding schemes in both block error rate and throughput efficiency.展开更多
Protective hardware is essential for mitigating damage caused by unavoidable falls in humanoid robots.Despite notable progress in fall protection hardware,the theoretical foundation for modeling and the feasibility of...Protective hardware is essential for mitigating damage caused by unavoidable falls in humanoid robots.Despite notable progress in fall protection hardware,the theoretical foundation for modeling and the feasibility of conducting full-scale fall experiments on robots or their surrogates remain somewhat limited.This paper proposes a method for optimizing the thickness of Expandable Polyethylene(EPE),which is used as back protection for the Chubao humanoid robot,based on small-scale impact test data to predict full-scale behavior.The optimal thickness is defined as a balance between compact design and protective effectiveness.An equivalent impact model characterized by four parameters:contact area S,mass m,fall height h,and cushioning material thickness d is introduced to describe impact conditions.The relationship between the peak impact acceleration ap and material thickness d,which forms the core of the method and gives rise to the name AP-D,is analyzed through their plotted curves.After introducing three characteristic parameters and two correction fac-tors,the relationship among the aforementioned variables is derived.Subsequently,both the optimal thickness do and its corresponding peak impact acceleration aop are predicted via nonlinear and linear regression models.Finally,the accuracy and effectiveness of the theoretically derived optimal thickness are validated on both a dummy and the actual robot.With the cushioning material applied,the peak chest acceleration is reduced to 41.57g for the dummy and 32.08g for the robot.展开更多
There has been an increasing emphasis on performing deep neural network(DNN)inference locally on edge devices due to challenges such as network congestion and security concerns.However,as DRAM process technology conti...There has been an increasing emphasis on performing deep neural network(DNN)inference locally on edge devices due to challenges such as network congestion and security concerns.However,as DRAM process technology continues to scale down,the bit-flip errors in the memory of edge devices become more frequent,thereby leading to substantial DNN inference accuracy loss.Though several techniques have been proposed to alleviate the accuracy loss in edge environments,they require complex computations and additional parity bits for error correction,thus resulting in significant performance and storage overheads.In this paper,we propose FeatherGuard,a data-driven lightweight error protection scheme for DNN inference on edge devices.FeatherGuard selectively protects critical bit positions(that have a significant impact on DNN inference accuracy)against bit-flip errors,by considering various DNN characteristics(e.g.,data format,layer-wise weight distribution,actually stored logical values).Thus,it achieves high error tolerability during DNN inference.Since FeatherGuard reduces the bit-flip errors based on only a few simple arithmetic operations(e.g.,NOT operations)without parity bits,it causes negligible performance overhead and no storage overhead.Our experimental results show that FeatherGuard improves the error tolerability by up to 6667×and 4000×,compared to the conventional systems and the state-of-the-art error protection technique for edge environments,respectively.展开更多
Objective:To evaluate the implementation effectiveness of standardized protective care procedures during hydrofluoric acid procedures in the dental department.Methods:This study was conducted from June 2023 to June 20...Objective:To evaluate the implementation effectiveness of standardized protective care procedures during hydrofluoric acid procedures in the dental department.Methods:This study was conducted from June 2023 to June 2025,selecting 90 patients who underwent hydrofluoric acid-related treatments in the outpatient dental department of this hospital during this period as subjects.Forty-five patients treated between June 2023 and June 2024 received conventional protective care(pre-intervention group),while 45 patients treated between June 2024 and June 2025 underwent the standardized protective care protocol(post-intervention group).Thirteen healthcare personnel participated in both pre-and post-intervention treatment phases.Based on the different nursing models,indicators such as the incidence of adverse events in patients and the exposure rate of healthcare personnel before and after implementation were compared to evaluate the effectiveness of the nursing intervention.Results:The incidence of oral mucosal irritation reactions in patients was lower after implementation,p<0.05.Compared with the pre-implementation period,the incidence of procedure-related adverse events decreased after implementation,p<0.05.There was a significant difference in the occupational exposure rate of healthcare personnel before and after implementation,with a higher rate observed before implementation(p<0.05).Post-implementation,healthcare personnel achieved higher compliance scores for pre-procedure preparation,intra-procedure protection,and post-procedure handling(p<0.05).Patient satisfaction with treatment was lower pre-implementation than post-implementation(p<0.05).Conclusion:Adherence to standardized protective care procedures during hydrofluoric acid operations by dental department staff in outpatient settings standardizes practitioner techniques,effectively prevents oral mucosal irritation in patients,reduces occupational exposure risks for staff,minimizes adverse procedural events,and consequently enhances patient treatment satisfaction.This demonstrates significant practical value.展开更多
Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identificat...Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identification and remediation of regional conservation gaps.To this end,we introduce the Framework for Conservation Priority Identification(FCPI).The framework integrates Morphological Spatial Pattern Analysis(MSPA),the Remote Sensing Ecological Index(RSEI),Circuit Theory,and the Minimum Cumulative Resistance(MCR)model to formulate a multidimensional conservation priority index.This index facilitates the identification of critical ecological network components and enables the dynamic prioritization of conservation efforts.A case study of Fuzhou City from 2014 to 2020 reveals that despite an overall improvement in regional environmental quality,the functionality of core ecological sources has markedly declined.Between 2014 and 2020,the number of ecological sources grew by 76.9%,yet their total area shrank by 13.9%.Concurrently,the number of ecological corridors rose from 27 to 53,extending their total length by 380.23 km,which indicates an intensifying trend of habitat fragmentation.Furthermore,a significant number of crucial ecological network nodes,particularly within Minhou County,lie explicitly outside the existing protected area system.This confirms the presence of conservation gaps and unveils the spatiotemporal dynamics of shifting conservation priorities.The research validates that the proposed FCPI can effectively diagnose the dynamic deficiencies within conservation systems.It offers scientific decisionsupport for local governments,facilitating a transition from isolated conservation efforts towards systematic and comprehensive ecological network governance.展开更多
BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking rec...BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking recovery.OBJECTIVE:To determine whether early suspension-protected training with a personal assistant machine for stroke patients enhances walking ability and prevents muscle spasms.METHODS:Thirty-two early-stage stroke patients from Shenzhen University General Hospital and the China Rehabilitation Research Center were randomly assigned to the experimental group(n=16)and the control group(n=16).Both groups underwent 4 weeks of gait training under the suspension protection system for 30 minutes daily,5 days a week.The experimental group used the personal assistant machine during training.Three-dimensional gait analysis(using the Cortex motion capture system),Brunnstrom staging,Fugl-Meyer Assessment for lower limb motor function,Fugl-Meyer balance function,and the modified Ashworth Scale were evaluated within 1 week before the intervention and after 4 weeks of intervention.RESULTS AND CONCLUSION:After the 4-week intervention,all outcome measures showed significant changes in each group.The experimental group had a small but significant increase in the modified Ashworth Scale score(P<0.05,d=|0.15|),while the control group had a large significant increase(P<0.05,d=|1.48|).The experimental group demonstrated greater improvements in walking speed(16.5 to 38.44 cm/s,P<0.05,d=|4.01|),step frequency(46.44 to 64.94 steps/min,P<0.05,d=|2.32|),stride length(15.50 to 29.81 cm,P<0.05,d=|3.44|),and peak hip and knee flexion(d=|1.82|to|2.17|).After treatment,the experimental group showed significantly greater improvements than the control group in walking speed(38.44 vs.26.63 cm/s,P<0.05,d=|2.75|),stride length,peak hip and knee flexion(d=|1.31|to|1.45|),step frequency(64.94 vs.59.38 steps/min,P<0.05,d=|0.85|),and a reduced support phase(bilateral:24.31%vs.28.38%,P<0.05,d=|0.88|;non-paretic:66.19%vs.70.13%,P<0.05,d=|0.94|).For early hemiplegia,personal assistant machine-assisted gait training under the suspension protection system helps establish a correct gait pattern,prevents muscle spasms,and improves motor function.展开更多
Hypervelocity rocket sled systems are critical for testing advanced military technologies,yet track damage at speeds exceeding Mach 5 remains a significant challenge for system reliability and performance.In this stud...Hypervelocity rocket sled systems are critical for testing advanced military technologies,yet track damage at speeds exceeding Mach 5 remains a significant challenge for system reliability and performance.In this study,we investigated the hypervelocity impact response and protection for highstrength U71 Mn or bainitic steel used in rocket sled tracks.Flyer plate impact experiments using a two-stage light-gas gun were conducted to study the hypervelocity collision response,followed by the microstructural characterization via optical microscope,scanning electron microscopy equipped with electron backscatter diffraction to reveal underlying damage mechanisms.Then,the calibrated thermalmechanical coupled finite element simulations using the Johnson-Cook constitutive model and MieGrüneisen equation of state were carried out.Results indicated that bainitic steel exhibits superior impact resistance with predominantly smooth scratch-dominated damage due to its higher ductility.In contrast,U71 Mn suffered significant material spallation and crack propagation arising from brittle fracture mechanisms.Zinc-rich epoxy primer coatings effectively mitigated stress concentration and temperature rise in the substrate at impacting velocities below 2.4 km/s,so as to suppress the microstructural damage such as adiabatic shear bands and dynamic recrystallization.However,coating protection diminished at ultra-high-speed impacts due to the coating failure.Dimensional analysis established quantitative relationships of the gouge damage size to projectile mass,impact velocity,and material yield strength.This study provides in-depth insights into damage mechanisms in hypervelocity rail systems,demonstrating that bainitic steel combined with protective coatings can significantly enhance impact resistance and system reliability,offering valuable guidance for the design and optimization of hypervelocity testing platforms.展开更多
Waterborne acrylic coatings are widely utilized due to their cost-effectiveness,high transparency,strong resistance to weather and chemicals,impressive mechanical properties,and excellent adhesion to various substrate...Waterborne acrylic coatings are widely utilized due to their cost-effectiveness,high transparency,strong resistance to weather and chemicals,impressive mechanical properties,and excellent adhesion to various substrates.In these coatings,a reactive emulsifier containing phosphate groups can be integrated into the molecular chain during polymerization,which enhances the coating's compactness and corrosion resistance.This work focuses on the synthesis of styrene-butyl acrylate(St-BA)latex and methyl methacrylate-butyl acrylate(MMA-BA)latex using the reactive phosphate emulsifier ANPEO_(10)-P_(1) through seed emulsion polymerization,achieving a conversion rate of approximately 99%and a solid content close to 50%.The resulting coatings from St-BA and MMA-BA latexes demonstrated long-term corrosion protection for carbon steel and aluminum alloy due to in-situ phosphatization,effectively preventing flash rust.Notably,the MMA-BA coating exhibited remarkable durability,enduring immersion for up to 1224 h(51 d)on Q 235 carbon steel before reaching the failure threshold(|Z|0.01 Hz£106Ω·cm^(2))on Q 235 carbon steel.On 5052 aluminum alloy,the St-BA coating maintained|Z|0.01 Hz>10^(8)Ω·cm^(2) for 480 h(20 d).Furthermore,the corrosion resistance of St-BA and MMA BA coatings on Q 235 steel sheet and 5052 aluminum alloy surpassed that of commercially available MMA-BA and St BA coatings after immersion in a 3.5 wt%NaCl aqueous solution.This work also delves into the anticorrosion mechanism of MMA-BA and St-BA coatings.展开更多
In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawate...In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawater,and NS4 using electrochemical impedance spectroscopy(EIS)to monitor the evolution of the substrate surface,which affects the current required to reach the protection potential(Eprot).Experimental data were collected as training datasets and analyzed using statistical methods,including box plots and correlation matrices.Subsequently,ANNs were applied to predict the current demand at different exposure times,enabling the estimation of electrochemical parameters(limiting voltage values)that can be used to optimize a self-regulating ICCP system.The obtained electrochemical parameters were then used,through Particle Swarm Optimization(PSO),to fine-tune an ANN-based proportional-integral-derivative(PID)controller for the ICCP system.展开更多
The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal materials.However,limited studies have applied ACM to the corrosion protection properties ...The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal materials.However,limited studies have applied ACM to the corrosion protection properties of organic coatings.This study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over time.Coatings with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in real-time.Throughout the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy coating.The trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface analysis.This alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic coatings.Compared with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.展开更多
Deep sea,with rich oil,gas,and mineral resources,plays an increasingly crucial role in scientific and industrial realms.However,the highly corrosive feature of deep sea hinders further exploration and development,whic...Deep sea,with rich oil,gas,and mineral resources,plays an increasingly crucial role in scientific and industrial realms.However,the highly corrosive feature of deep sea hinders further exploration and development,which requires metal materials with robust corrosion resistance.This review covers an in-depth and all-around overview of the up-to-date advances in corrosion and protection of metals in deep-sea environment.Firstly,the unique characteristics of deep-sea environment are summarized in detail.Subsequently,the corrosion performances of metals in both in situ and simulated deep-sea environments are illustrated systematically.Furthermore,corrosion prevent strategies of metals,including sacrificial anode protection,organic coatings,as well as coatings achieved by physical vapor deposition(PVD coatings),are highlighted.Finally,we outline current challenges and development trends of corrosion and protection of metals in deep-sea environment in the future.The purpose of this review is not only to summarize the recent progress on metal corrosion and protection in deep sea,but also to aid us in understanding them more comprehensively and deeply in a short time,so as to boost their fast development.展开更多
The waterproof performance,mechanical properties,chemical composition,microstructure,and pore structure of hydrophobically-modified geopolymer concrete are investigated before and after dry-wet cycles,to determine the...The waterproof performance,mechanical properties,chemical composition,microstructure,and pore structure of hydrophobically-modified geopolymer concrete are investigated before and after dry-wet cycles,to determine the long-term feasibility of using hydrophobically-modified geopolymer concrete in wet environments.We use two types of organic modifying agents:polydimethylsiloxane(PDMS)and sodium methyl siliconate(SMS).The experimental results show that incorporating 2%–6%PDMS or 5%–15%SMS can make the concrete hydrophobic,with water absorption and chloride transport rates decreasing by up to 94.3%.We also analyze the bonding modes of organic molecules and geopolymer gels,as well as their evolution mechanisms during dry-wet cycles.PDMS-modified geopolymer concrete is found to exhibit long-term waterproof performance that is not weakened by dry-wet cycles.This is attributed to the robust combination of organic components and the geopolymer gel skeleton formed through phase cross-linking.Meanwhile,PDMS-modified geopolymer concrete’s hydrophobicity,strength,and microstructure are essentially unaffected.In contrast,SMS-modified geopolymer concrete shows higher water sensitivity,although it does maintain efficient waterproof performance.Due to relatively low binding energy,the dry-wet cycles may lead to the detachment of some SMS molecules from the gel network,which results in a decrease of 18.6%in compressive strength and an increase of 37.6%in total porosity.This work confirms the utility of hydrophobically-modified geopolymer concrete as a building material for long-term service in wet environments,for instance,areas with frequent precipitation,or splash and tidal zones.展开更多
Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the ...Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the minimum safe thickness of water-proof rock mass,a simplified calculation model of water-proof rock mass thickness when the karst cave is located at any location around the tunnel is established,and the influence of multiple factors on the overall stability of water-proof rock mass is considered.Based on the cusp catastrophe theory,the analytical expressions for the safety thickness of waterproof rock mass are derived.Based on the finite difference principle,the analytical expressions of the safety thickness of water-proof rock mass are verified.In order to improve the application range of the analytical formula derived in this paper,the analytical formula is optimized based on the instability principle differences between the simplified calculation model and the elastic compressive bar.The research results show that the necessary condition solution is more applicable and much safer than the sufficient condition solution.Tectonic stress,rock beam length and karst cave water pressure are significantly positively correlated with the safe thickness of the waterproof rock mass.The calculated results of the semioptimized formula and the unoptimized formula are constant values,independent of the karst cave location.While the calculated results of the fully optimized formula are variable values,correlated with the karst cave location,the thickness of the waterproof rock mass gradually decreases as the karst cave location moves from the top of the tunnel to the bottom of the tunnel.The unoptimized formula does not consider the influence of the lateral force of the rock beam,and is not suitable for the working condition with large lateral force,the calculation results of the semi-optimized formula and the fully optimized formula are not very different and are biased to safety,so it can be given priority.展开更多
The regenerative braking energy utilization system(RBEUS)stands as a promising technique for improving the efficiency and power quality of electrified railways.Beyond the vital aspects of energy management and control...The regenerative braking energy utilization system(RBEUS)stands as a promising technique for improving the efficiency and power quality of electrified railways.Beyond the vital aspects of energy management and control strategies,ensuring fault protection is paramount for the secure and steady operation of the traction power supply system(TPSS)integrated with RBEUS.This paper introduces an innovative protection scheme tailored to diverse RBEUS application scenarios.Firstly,fault categories are streamlined into three levels:system,equipment,and warning.Subsequently,a novel multi-port active power differential protection method,aligned with RBEUS operational principles,is crafted to serve as a comprehensive and sensitive main protection.Building upon this foundation,a hierarchical protection structure for RBEUS is established,addressing the intricacies and variations in fault types while boosting anti-disturbance capabilities under faulty conditions.Embracing the principle of railway-oriented safety,a collaborative RBEUS-TPSS protection scheme is put forth.Finally,through simulated scenarios encompassing various fault conditions,the proposed scheme’s feasibility and effectiveness are convincingly validated.展开更多
Neurons are notoriously vulnerable cell types.Even the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological cond...Neurons are notoriously vulnerable cell types.Even the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological conditions,including stroke,head trauma,and neurodegenerative disease,can generate stress in neurons,affecting their survival and proper function.In most neural pathologies,mitochondria become dysfunctional and this plays a pivotal role in the process of cell death.The challenge over the last few decades has been to develop effective interventions that improve neuronal homeostasis under pathological conditions.Such interventions,often referred to as disease-modifying or neuroprotective,have,however,proved frustratingly elusive,at both preclinical and,in particular,clinical levels.In this perspective,we highlight two factors that we feel are key to the development of effective neuroprotective treatments.These are:firstly,the choice of dose of intervention and method of application,and secondly,the selection of subjects,whether they be patients or the animal model.展开更多
Traditional impact protection structures(IPSs)dissipate impact energy according to the plastic dissipation mechanism,which is only effective for single impacts due to the irreversible deformation of structures.To achi...Traditional impact protection structures(IPSs)dissipate impact energy according to the plastic dissipation mechanism,which is only effective for single impacts due to the irreversible deformation of structures.To achieve multi-impact protection,this paper proposes a novel chiral periodic structure with the deformation self-recovery function and the high energy conversion efficiency based on the flexoelectric mechanism.A theoretical model is formulated on the electromechanical responses of a flexoelectric beam under rotational boundaries.The equivalent stiffness and damping characteristics are subsequently derived to construct the electromechanical responses of the structure under constant velocity and mass impacts.Discussions are addressed for the influence of the structural scale effect and resistance on the electromechanical responses.The results show that the energy conversion efficiency increases by 2 to 3 orders of magnitude,reaching as high as 85.3%,which can match well with those of structures reported in the literature based on the plastic energy dissipating mechanism.展开更多
With the rapid development of web3.0 applications,the volume of data sharing is increasing,the inefficiency of big data file sharing and the problem of data privacy leakage are becoming more and more prominent,and the...With the rapid development of web3.0 applications,the volume of data sharing is increasing,the inefficiency of big data file sharing and the problem of data privacy leakage are becoming more and more prominent,and the existing data sharing schemes have been difficult to meet the growing demand for data sharing,this paper aims at exploring a secure,efficient and privacy-protecting data sharing scheme under web3.0 applications.Specifically,this paper adopts interplanetary file system(IPFS)technology to realize the storage of large data files to solve the problem of blockchain storage capacity limitation,and utilizes ciphertext policy attribute-based encryption(CP-ABE)and proxy re-encryption(PRE)technology to realize secure multi-party sharing and finegrained access control of data.This paper provides the detailed algorithm design and implementation of data sharing phases and processes,and analyzes the algorithms from the perspectives of security,privacy protection,and performance.展开更多
Global marine ecosystems are signiicantly endangered by microplastic pollution,leading to comprehensive investigations into its distribution and impacts on the health of ecosystem.This research employs the Alseamar Au...Global marine ecosystems are signiicantly endangered by microplastic pollution,leading to comprehensive investigations into its distribution and impacts on the health of ecosystem.This research employs the Alseamar Autonomous Underwater Vehicle(AUV)known as Glider to investigate microplastic concentrations within the Al Hoceima Marine Protected Area(MPA).Our objective is to identify spatial patterns that reveal pollution hotspots and furnish data for targeted conservation efforts and pollution prevention.We aim to identify regions with elevated microplastic concentrations by meticulously analyzing microplastic level graphs,with a speciic focus on temporal variations.The results reveal notable patterns,such as increased densities aroundishing harbors and near urban centers,potentially linked to anthropogenic activities.Additionally,we observe variations in pollution levels throughout different glider operation cycles,underscoring the importance of understanding the spatio‑temporal dynamics of microplastic distribution.Al Hoceima Marine protected areas exhibiting lower microplastic concentrations illustrate the eficacy of such zones in alleviating pollution impacts,thereby underscoring the signiicance of conservation efforts in safeguarding marine biodiversity and ecosystem resilience.Ultimately,our research enhances our comprehension of the pressures exerted by humans on marine environments and underscores the necessity of proactive conservation measures to shield marine ecosystems from the threats posed by microplastic pollution.展开更多
Aqueous-electrolyte-based zinc-ion batteries(ZIBs),which have significant advantages over other batteries,including low cost,high safety,high ionic conductivity,and a natural abundance of zinc,have been regarded as a ...Aqueous-electrolyte-based zinc-ion batteries(ZIBs),which have significant advantages over other batteries,including low cost,high safety,high ionic conductivity,and a natural abundance of zinc,have been regarded as a potential alternative to lithium-ion batteries(LIBs).ZIBs still face some critical challenges,however,especially for building a reversible zinc anode.To address the reversibility of zinc anode,great efforts have been made on intrinsic anode engineering and anode interface modification.Less attention has been devoted to the electrolyte additives,however,which could not only significantly improve the reversibility of zinc anode,but also determine the viability and overall performance of ZIBs.This review aims to provide an overview of the two main functions of electrolyte additives,followed by details on six reasons why additives might improve the performance of ZIBs from the perspectives of creating new layers and regulating current plating/stripping processes.Furthermore,the remaining difficulties and potential directions for additives in aqueous ZIBs are also highlighted.展开更多
基金Supported by the Special Project for Supporting the Development of Biomedicine and Health Industry in Hangzhou City,No.2022WJC123Zhejiang Province Traditional Chinese Medicine Science and Technology Plan Project,No.2022ZA143.
文摘BACKGROUND Long-term antipsychotic therapy in psychiatric patients carries significant cardiovascular risks,including QT interval prolongation,myocardial injury,and functional impairment.Guanxinning,a traditional Chinese medicine formulation,has demonstrated cardioprotective potential in preclinical studies,but clinical evidence in this population remains limited.AIM To evaluate the cardioprotective effects of Guanxinning against antipsychotic-induced cardiac injury in long-term hospitalized psychiatric patients.METHODS A randomized,double-blind,placebo-controlled trial was conducted with 120 psychiatric inpatients receiving chronic antipsychotic therapy.Participants were allocated to:Intervention group:Conventional antipsychotics+Guanxinning tablets(0.38 g×4 tablets,ter in die);Control group:Conventional antipsychotics+identical placebo;Cardiac assessments at baseline and 12 months included:Electrocardiography(corrected QT interval),echocardiography(left ventricular ejection fraction,left ventricular end-diastolic diameter),serum biomarkers(cardiac troponin I,B-type natriuretic peptide,superoxide dismutase,malondialdehyde,high-sensitivity C-reactive protein).RESULTS Compared to controls,the Guanxinning group showed:Electrophysiological improvement:Corrected QT shortening(438±25 milliseconds vs 465±30 milliseconds,P<0.01).Functional enhancement:Left ventricular ejection fraction increase(58.5%±5.2%vs 53.8%±4.8%,P<0.05),left ventricular end-diastolic diameter reduction(49.8±3.5 mm vs 52.6±3.8 mm,P<0.05),Biochemical modulation:Reduced myocardial injury markers(cardiac troponin I:0.009 ng/mL vs 0.014 ng/mL;B-type natriuretic peptide:52 pg/mL vs 78 pg/mL,P<0.001),improved oxidative stress(superoxide dismutase:↑13.3 U/mL;malondialdehyde:↓0.9 nmol/mL,P<0.001),attenuated inflammation(high-sensitivity C-reactive protein:2.0 mg/L vs 3.2 mg/L,P<0.001).CONCLUSION Guanxinning significantly mitigates antipsychotic-induced cardiac injury in psychiatric patients,demonstrating:Normalization of electrophysiological parameters,Preservation of systolic/diastolic function,suppression of oxidative stress and inflammation.These findings support its clinical application as an adjunctive cardioprotective therapy,potentially through inhibition of myocardial apoptosis and antioxidant upregulation.
基金supported by National Natural Science Foundation of China(No.62301008)China Postdoctoral Science Foundation(No.2022M720272)New Cornerstone Science Foundation through the XPLORER PRIZE。
文摘Mobile communications are reaching out to every aspect of our daily life,necessitating highefficiency data transmission and support for diverse data types and communication scenarios.Polar codes have emerged as a promising solution due to their outstanding error-correction performance and low complexity.Unequal error protection(UEP)involves nonuniform error safeguarding for distinct data segments,achieving a fine balance between error resilience and resource allocation,which ultimately enhancing system performance and efficiency.In this paper,we propose a novel class of UEP rateless polar codes.The codes are designed based on matrix extension of polar codes,and elegant mapping and duplication operations are designed to achieve UEP property while preserving the overall performance of conventional polar codes.Superior UEP performance is attained without significant modifications to conventional polar codes,making it straightforward for compatibility with existing polar codes.A theoretical analysis is conducted on the block error rate and throughput efficiency performance.To the best of our knowledge,this work provides the first theoretical performance analysis of UEP rateless polar codes.Simulation results show that the proposed codes significantly outperform existing polar coding schemes in both block error rate and throughput efficiency.
基金Natural Science Foundation of Beijing Municipality under Grant L243004the National Natural Science Foundation of China under Grant 62403060.
文摘Protective hardware is essential for mitigating damage caused by unavoidable falls in humanoid robots.Despite notable progress in fall protection hardware,the theoretical foundation for modeling and the feasibility of conducting full-scale fall experiments on robots or their surrogates remain somewhat limited.This paper proposes a method for optimizing the thickness of Expandable Polyethylene(EPE),which is used as back protection for the Chubao humanoid robot,based on small-scale impact test data to predict full-scale behavior.The optimal thickness is defined as a balance between compact design and protective effectiveness.An equivalent impact model characterized by four parameters:contact area S,mass m,fall height h,and cushioning material thickness d is introduced to describe impact conditions.The relationship between the peak impact acceleration ap and material thickness d,which forms the core of the method and gives rise to the name AP-D,is analyzed through their plotted curves.After introducing three characteristic parameters and two correction fac-tors,the relationship among the aforementioned variables is derived.Subsequently,both the optimal thickness do and its corresponding peak impact acceleration aop are predicted via nonlinear and linear regression models.Finally,the accuracy and effectiveness of the theoretically derived optimal thickness are validated on both a dummy and the actual robot.With the cushioning material applied,the peak chest acceleration is reduced to 41.57g for the dummy and 32.08g for the robot.
基金the“Convergence and Open sharing System”Project,supported by the Ministry of Education and National Research Foundation of Korea.
文摘There has been an increasing emphasis on performing deep neural network(DNN)inference locally on edge devices due to challenges such as network congestion and security concerns.However,as DRAM process technology continues to scale down,the bit-flip errors in the memory of edge devices become more frequent,thereby leading to substantial DNN inference accuracy loss.Though several techniques have been proposed to alleviate the accuracy loss in edge environments,they require complex computations and additional parity bits for error correction,thus resulting in significant performance and storage overheads.In this paper,we propose FeatherGuard,a data-driven lightweight error protection scheme for DNN inference on edge devices.FeatherGuard selectively protects critical bit positions(that have a significant impact on DNN inference accuracy)against bit-flip errors,by considering various DNN characteristics(e.g.,data format,layer-wise weight distribution,actually stored logical values).Thus,it achieves high error tolerability during DNN inference.Since FeatherGuard reduces the bit-flip errors based on only a few simple arithmetic operations(e.g.,NOT operations)without parity bits,it causes negligible performance overhead and no storage overhead.Our experimental results show that FeatherGuard improves the error tolerability by up to 6667×and 4000×,compared to the conventional systems and the state-of-the-art error protection technique for edge environments,respectively.
基金Construction of Standardized Protective Nursing Plan for Hydrofluoric Acid Operation in Stomatology and Re search on Injury Prevention Effect(Project No.:FZ2025101)。
文摘Objective:To evaluate the implementation effectiveness of standardized protective care procedures during hydrofluoric acid procedures in the dental department.Methods:This study was conducted from June 2023 to June 2025,selecting 90 patients who underwent hydrofluoric acid-related treatments in the outpatient dental department of this hospital during this period as subjects.Forty-five patients treated between June 2023 and June 2024 received conventional protective care(pre-intervention group),while 45 patients treated between June 2024 and June 2025 underwent the standardized protective care protocol(post-intervention group).Thirteen healthcare personnel participated in both pre-and post-intervention treatment phases.Based on the different nursing models,indicators such as the incidence of adverse events in patients and the exposure rate of healthcare personnel before and after implementation were compared to evaluate the effectiveness of the nursing intervention.Results:The incidence of oral mucosal irritation reactions in patients was lower after implementation,p<0.05.Compared with the pre-implementation period,the incidence of procedure-related adverse events decreased after implementation,p<0.05.There was a significant difference in the occupational exposure rate of healthcare personnel before and after implementation,with a higher rate observed before implementation(p<0.05).Post-implementation,healthcare personnel achieved higher compliance scores for pre-procedure preparation,intra-procedure protection,and post-procedure handling(p<0.05).Patient satisfaction with treatment was lower pre-implementation than post-implementation(p<0.05).Conclusion:Adherence to standardized protective care procedures during hydrofluoric acid operations by dental department staff in outpatient settings standardizes practitioner techniques,effectively prevents oral mucosal irritation in patients,reduces occupational exposure risks for staff,minimizes adverse procedural events,and consequently enhances patient treatment satisfaction.This demonstrates significant practical value.
基金supported by the Natural Science Foundation of Fujian Province(2023J01434)the Science and Technology Innovation Special Fund Project of Fujian Agriculture and Forestry University(KFb22028XA)。
文摘Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identification and remediation of regional conservation gaps.To this end,we introduce the Framework for Conservation Priority Identification(FCPI).The framework integrates Morphological Spatial Pattern Analysis(MSPA),the Remote Sensing Ecological Index(RSEI),Circuit Theory,and the Minimum Cumulative Resistance(MCR)model to formulate a multidimensional conservation priority index.This index facilitates the identification of critical ecological network components and enables the dynamic prioritization of conservation efforts.A case study of Fuzhou City from 2014 to 2020 reveals that despite an overall improvement in regional environmental quality,the functionality of core ecological sources has markedly declined.Between 2014 and 2020,the number of ecological sources grew by 76.9%,yet their total area shrank by 13.9%.Concurrently,the number of ecological corridors rose from 27 to 53,extending their total length by 380.23 km,which indicates an intensifying trend of habitat fragmentation.Furthermore,a significant number of crucial ecological network nodes,particularly within Minhou County,lie explicitly outside the existing protected area system.This confirms the presence of conservation gaps and unveils the spatiotemporal dynamics of shifting conservation priorities.The research validates that the proposed FCPI can effectively diagnose the dynamic deficiencies within conservation systems.It offers scientific decisionsupport for local governments,facilitating a transition from isolated conservation efforts towards systematic and comprehensive ecological network governance.
文摘BACKGROUND:Hemiplegia,a prevalent stroke-related condition,is often studied for motor dysfunction;however,spasticity remains under-researched.Abnormal muscle tone significantly hinders hemiplegic patients’walking recovery.OBJECTIVE:To determine whether early suspension-protected training with a personal assistant machine for stroke patients enhances walking ability and prevents muscle spasms.METHODS:Thirty-two early-stage stroke patients from Shenzhen University General Hospital and the China Rehabilitation Research Center were randomly assigned to the experimental group(n=16)and the control group(n=16).Both groups underwent 4 weeks of gait training under the suspension protection system for 30 minutes daily,5 days a week.The experimental group used the personal assistant machine during training.Three-dimensional gait analysis(using the Cortex motion capture system),Brunnstrom staging,Fugl-Meyer Assessment for lower limb motor function,Fugl-Meyer balance function,and the modified Ashworth Scale were evaluated within 1 week before the intervention and after 4 weeks of intervention.RESULTS AND CONCLUSION:After the 4-week intervention,all outcome measures showed significant changes in each group.The experimental group had a small but significant increase in the modified Ashworth Scale score(P<0.05,d=|0.15|),while the control group had a large significant increase(P<0.05,d=|1.48|).The experimental group demonstrated greater improvements in walking speed(16.5 to 38.44 cm/s,P<0.05,d=|4.01|),step frequency(46.44 to 64.94 steps/min,P<0.05,d=|2.32|),stride length(15.50 to 29.81 cm,P<0.05,d=|3.44|),and peak hip and knee flexion(d=|1.82|to|2.17|).After treatment,the experimental group showed significantly greater improvements than the control group in walking speed(38.44 vs.26.63 cm/s,P<0.05,d=|2.75|),stride length,peak hip and knee flexion(d=|1.31|to|1.45|),step frequency(64.94 vs.59.38 steps/min,P<0.05,d=|0.85|),and a reduced support phase(bilateral:24.31%vs.28.38%,P<0.05,d=|0.88|;non-paretic:66.19%vs.70.13%,P<0.05,d=|0.94|).For early hemiplegia,personal assistant machine-assisted gait training under the suspension protection system helps establish a correct gait pattern,prevents muscle spasms,and improves motor function.
基金financial support from the National Key Research and Development Program(Grant No.2024YFA1209801)the National Natural Science Foundation of China(Grant Nos.12302140,12325204)+4 种基金the China Postdoctoral Science Foundation(Grant No.2023M732794)the Fundamental Research Funds for the Central Universities of China(Grant No.sxzy012023213)the Scientific Research Program of Shaanxi Province(Grant No.2023JC-XJ-02)the Young Talent Support Program of Xi'an Science and Technology Association(Grant No.959202413069)Postdoctoral Fellowship Program(Grade B)of China Postdoctoral Science Foundation(Grant No.GZB20230575)。
文摘Hypervelocity rocket sled systems are critical for testing advanced military technologies,yet track damage at speeds exceeding Mach 5 remains a significant challenge for system reliability and performance.In this study,we investigated the hypervelocity impact response and protection for highstrength U71 Mn or bainitic steel used in rocket sled tracks.Flyer plate impact experiments using a two-stage light-gas gun were conducted to study the hypervelocity collision response,followed by the microstructural characterization via optical microscope,scanning electron microscopy equipped with electron backscatter diffraction to reveal underlying damage mechanisms.Then,the calibrated thermalmechanical coupled finite element simulations using the Johnson-Cook constitutive model and MieGrüneisen equation of state were carried out.Results indicated that bainitic steel exhibits superior impact resistance with predominantly smooth scratch-dominated damage due to its higher ductility.In contrast,U71 Mn suffered significant material spallation and crack propagation arising from brittle fracture mechanisms.Zinc-rich epoxy primer coatings effectively mitigated stress concentration and temperature rise in the substrate at impacting velocities below 2.4 km/s,so as to suppress the microstructural damage such as adiabatic shear bands and dynamic recrystallization.However,coating protection diminished at ultra-high-speed impacts due to the coating failure.Dimensional analysis established quantitative relationships of the gouge damage size to projectile mass,impact velocity,and material yield strength.This study provides in-depth insights into damage mechanisms in hypervelocity rail systems,demonstrating that bainitic steel combined with protective coatings can significantly enhance impact resistance and system reliability,offering valuable guidance for the design and optimization of hypervelocity testing platforms.
基金Project(52373065)supported by the National Natural Science Foundation of ChinaProject(2220004002898)supported by the Zhuhai Industry University Research Cooperation and Basic and Applied Research Projects,China。
文摘Waterborne acrylic coatings are widely utilized due to their cost-effectiveness,high transparency,strong resistance to weather and chemicals,impressive mechanical properties,and excellent adhesion to various substrates.In these coatings,a reactive emulsifier containing phosphate groups can be integrated into the molecular chain during polymerization,which enhances the coating's compactness and corrosion resistance.This work focuses on the synthesis of styrene-butyl acrylate(St-BA)latex and methyl methacrylate-butyl acrylate(MMA-BA)latex using the reactive phosphate emulsifier ANPEO_(10)-P_(1) through seed emulsion polymerization,achieving a conversion rate of approximately 99%and a solid content close to 50%.The resulting coatings from St-BA and MMA-BA latexes demonstrated long-term corrosion protection for carbon steel and aluminum alloy due to in-situ phosphatization,effectively preventing flash rust.Notably,the MMA-BA coating exhibited remarkable durability,enduring immersion for up to 1224 h(51 d)on Q 235 carbon steel before reaching the failure threshold(|Z|0.01 Hz£106Ω·cm^(2))on Q 235 carbon steel.On 5052 aluminum alloy,the St-BA coating maintained|Z|0.01 Hz>10^(8)Ω·cm^(2) for 480 h(20 d).Furthermore,the corrosion resistance of St-BA and MMA BA coatings on Q 235 steel sheet and 5052 aluminum alloy surpassed that of commercially available MMA-BA and St BA coatings after immersion in a 3.5 wt%NaCl aqueous solution.This work also delves into the anticorrosion mechanism of MMA-BA and St-BA coatings.
文摘In this study,artificial neural networks(ANNs)were implemented to determine design parameters for an impressed current cathodic protection(ICCP)prototype.An ASTM A36 steel plate was tested in 3.5%NaCl solution,seawater,and NS4 using electrochemical impedance spectroscopy(EIS)to monitor the evolution of the substrate surface,which affects the current required to reach the protection potential(Eprot).Experimental data were collected as training datasets and analyzed using statistical methods,including box plots and correlation matrices.Subsequently,ANNs were applied to predict the current demand at different exposure times,enabling the estimation of electrochemical parameters(limiting voltage values)that can be used to optimize a self-regulating ICCP system.The obtained electrochemical parameters were then used,through Particle Swarm Optimization(PSO),to fine-tune an ANN-based proportional-integral-derivative(PID)controller for the ICCP system.
基金financially supported by the National Natural Science Foundation of China(No.52371049)the Young Elite Scientists Sponsorship Program by the China Association for Science and Technology(YESS,No.2020QNRC001)the National Science and Technology Resources Investigation Program of China(Nos.2021FY100603 and 2019FY101404)。
文摘The atmospheric corrosion monitoring(ACM)technique has been widely employed to track the real-time corrosion behavior of metal materials.However,limited studies have applied ACM to the corrosion protection properties of organic coatings.This study compared a bare epoxy coating with one containing zinc phosphate corrosion inhibitors,both applied on ACM sensors,to observe their corrosion protection properties over time.Coatings with artificial damage via scratches were exposed to immersion and alternating dry and wet environments,which allowed for monitoring galvanic corrosion currents in real-time.Throughout the corrosion tests,the ACM currents of the zinc phosphate/epoxy coating were considerably lower than those of the blank epoxy coating.The trend in ACM current variations closely matched the results obtained from regular electrochemical tests and surface analysis.This alignment highlights the potential of the ACM technique in evaluating the corrosion protection capabilities of organic coatings.Compared with the blank epoxy coating,the zinc phosphate/epoxy coating showed much-decreased ACM current values that confirmed the effective inhibition of zinc phosphate against steel corrosion beneath the damaged coating.
基金the National Key R&D Program of China(No.2022YFB3808800)the National Natural Science Foundation of China(Nos.52301406 and 52375219)+2 种基金the Natural Science Foundation of Zhejiang Province(No.LR21E050001)the China Postdoctoral Science Foundation(No.2023M733600)the Ningbo Natural Science Foundation(No.2023J329).
文摘Deep sea,with rich oil,gas,and mineral resources,plays an increasingly crucial role in scientific and industrial realms.However,the highly corrosive feature of deep sea hinders further exploration and development,which requires metal materials with robust corrosion resistance.This review covers an in-depth and all-around overview of the up-to-date advances in corrosion and protection of metals in deep-sea environment.Firstly,the unique characteristics of deep-sea environment are summarized in detail.Subsequently,the corrosion performances of metals in both in situ and simulated deep-sea environments are illustrated systematically.Furthermore,corrosion prevent strategies of metals,including sacrificial anode protection,organic coatings,as well as coatings achieved by physical vapor deposition(PVD coatings),are highlighted.Finally,we outline current challenges and development trends of corrosion and protection of metals in deep-sea environment in the future.The purpose of this review is not only to summarize the recent progress on metal corrosion and protection in deep sea,but also to aid us in understanding them more comprehensively and deeply in a short time,so as to boost their fast development.
基金supported by the National Natural Science Foundation of China(Nos.52101328 and 52171277)the National Key Research and Development Program of China(No.2022YFE0109200)+1 种基金the Foundation of the Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(No.2022SZ-TD006)the Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(CPSF)(No.GZB20230653)。
文摘The waterproof performance,mechanical properties,chemical composition,microstructure,and pore structure of hydrophobically-modified geopolymer concrete are investigated before and after dry-wet cycles,to determine the long-term feasibility of using hydrophobically-modified geopolymer concrete in wet environments.We use two types of organic modifying agents:polydimethylsiloxane(PDMS)and sodium methyl siliconate(SMS).The experimental results show that incorporating 2%–6%PDMS or 5%–15%SMS can make the concrete hydrophobic,with water absorption and chloride transport rates decreasing by up to 94.3%.We also analyze the bonding modes of organic molecules and geopolymer gels,as well as their evolution mechanisms during dry-wet cycles.PDMS-modified geopolymer concrete is found to exhibit long-term waterproof performance that is not weakened by dry-wet cycles.This is attributed to the robust combination of organic components and the geopolymer gel skeleton formed through phase cross-linking.Meanwhile,PDMS-modified geopolymer concrete’s hydrophobicity,strength,and microstructure are essentially unaffected.In contrast,SMS-modified geopolymer concrete shows higher water sensitivity,although it does maintain efficient waterproof performance.Due to relatively low binding energy,the dry-wet cycles may lead to the detachment of some SMS molecules from the gel network,which results in a decrease of 18.6%in compressive strength and an increase of 37.6%in total porosity.This work confirms the utility of hydrophobically-modified geopolymer concrete as a building material for long-term service in wet environments,for instance,areas with frequent precipitation,or splash and tidal zones.
基金jointly funded by the guangxi Science and Technology Base and Talent Project(AD23026104)the Key Research and Development Program Project in Guangxi(AB23026121)。
文摘Due to the influence of karst cave development and route selection,the location relationship between concealed karst cave and tunnel is more random.In order to explore the influence rule of karst cave location on the minimum safe thickness of water-proof rock mass,a simplified calculation model of water-proof rock mass thickness when the karst cave is located at any location around the tunnel is established,and the influence of multiple factors on the overall stability of water-proof rock mass is considered.Based on the cusp catastrophe theory,the analytical expressions for the safety thickness of waterproof rock mass are derived.Based on the finite difference principle,the analytical expressions of the safety thickness of water-proof rock mass are verified.In order to improve the application range of the analytical formula derived in this paper,the analytical formula is optimized based on the instability principle differences between the simplified calculation model and the elastic compressive bar.The research results show that the necessary condition solution is more applicable and much safer than the sufficient condition solution.Tectonic stress,rock beam length and karst cave water pressure are significantly positively correlated with the safe thickness of the waterproof rock mass.The calculated results of the semioptimized formula and the unoptimized formula are constant values,independent of the karst cave location.While the calculated results of the fully optimized formula are variable values,correlated with the karst cave location,the thickness of the waterproof rock mass gradually decreases as the karst cave location moves from the top of the tunnel to the bottom of the tunnel.The unoptimized formula does not consider the influence of the lateral force of the rock beam,and is not suitable for the working condition with large lateral force,the calculation results of the semi-optimized formula and the fully optimized formula are not very different and are biased to safety,so it can be given priority.
基金supported by the National Natural Science Foundation of China(Nos.52107126 and52077179)the Key Regional Innovation and Development Joint Fund Project(No.2023YFB2303901)the funding of Chengdu Guojia Electrical Engineering Co.,Ltd.(No.NEEC-2022-B11).
文摘The regenerative braking energy utilization system(RBEUS)stands as a promising technique for improving the efficiency and power quality of electrified railways.Beyond the vital aspects of energy management and control strategies,ensuring fault protection is paramount for the secure and steady operation of the traction power supply system(TPSS)integrated with RBEUS.This paper introduces an innovative protection scheme tailored to diverse RBEUS application scenarios.Firstly,fault categories are streamlined into three levels:system,equipment,and warning.Subsequently,a novel multi-port active power differential protection method,aligned with RBEUS operational principles,is crafted to serve as a comprehensive and sensitive main protection.Building upon this foundation,a hierarchical protection structure for RBEUS is established,addressing the intricacies and variations in fault types while boosting anti-disturbance capabilities under faulty conditions.Embracing the principle of railway-oriented safety,a collaborative RBEUS-TPSS protection scheme is put forth.Finally,through simulated scenarios encompassing various fault conditions,the proposed scheme’s feasibility and effectiveness are convincingly validated.
基金supported by Fonds Clinatec and COVEA France(to JM).
文摘Neurons are notoriously vulnerable cell types.Even the slightest change in their internal and/or external environments will cause much distress and dysfunction,leading often to their death.A range of pathological conditions,including stroke,head trauma,and neurodegenerative disease,can generate stress in neurons,affecting their survival and proper function.In most neural pathologies,mitochondria become dysfunctional and this plays a pivotal role in the process of cell death.The challenge over the last few decades has been to develop effective interventions that improve neuronal homeostasis under pathological conditions.Such interventions,often referred to as disease-modifying or neuroprotective,have,however,proved frustratingly elusive,at both preclinical and,in particular,clinical levels.In this perspective,we highlight two factors that we feel are key to the development of effective neuroprotective treatments.These are:firstly,the choice of dose of intervention and method of application,and secondly,the selection of subjects,whether they be patients or the animal model.
基金Project supported by the National Natural Science Foundation of China(No.12272138)。
文摘Traditional impact protection structures(IPSs)dissipate impact energy according to the plastic dissipation mechanism,which is only effective for single impacts due to the irreversible deformation of structures.To achieve multi-impact protection,this paper proposes a novel chiral periodic structure with the deformation self-recovery function and the high energy conversion efficiency based on the flexoelectric mechanism.A theoretical model is formulated on the electromechanical responses of a flexoelectric beam under rotational boundaries.The equivalent stiffness and damping characteristics are subsequently derived to construct the electromechanical responses of the structure under constant velocity and mass impacts.Discussions are addressed for the influence of the structural scale effect and resistance on the electromechanical responses.The results show that the energy conversion efficiency increases by 2 to 3 orders of magnitude,reaching as high as 85.3%,which can match well with those of structures reported in the literature based on the plastic energy dissipating mechanism.
基金supported by the National Natural Science Foundation of China(Grant No.U24B20146)the National Key Research and Development Plan in China(Grant No.2020YFB1005500)Beijing Natural Science Foundation Project(No.M21034).
文摘With the rapid development of web3.0 applications,the volume of data sharing is increasing,the inefficiency of big data file sharing and the problem of data privacy leakage are becoming more and more prominent,and the existing data sharing schemes have been difficult to meet the growing demand for data sharing,this paper aims at exploring a secure,efficient and privacy-protecting data sharing scheme under web3.0 applications.Specifically,this paper adopts interplanetary file system(IPFS)technology to realize the storage of large data files to solve the problem of blockchain storage capacity limitation,and utilizes ciphertext policy attribute-based encryption(CP-ABE)and proxy re-encryption(PRE)technology to realize secure multi-party sharing and finegrained access control of data.This paper provides the detailed algorithm design and implementation of data sharing phases and processes,and analyzes the algorithms from the perspectives of security,privacy protection,and performance.
文摘Global marine ecosystems are signiicantly endangered by microplastic pollution,leading to comprehensive investigations into its distribution and impacts on the health of ecosystem.This research employs the Alseamar Autonomous Underwater Vehicle(AUV)known as Glider to investigate microplastic concentrations within the Al Hoceima Marine Protected Area(MPA).Our objective is to identify spatial patterns that reveal pollution hotspots and furnish data for targeted conservation efforts and pollution prevention.We aim to identify regions with elevated microplastic concentrations by meticulously analyzing microplastic level graphs,with a speciic focus on temporal variations.The results reveal notable patterns,such as increased densities aroundishing harbors and near urban centers,potentially linked to anthropogenic activities.Additionally,we observe variations in pollution levels throughout different glider operation cycles,underscoring the importance of understanding the spatio‑temporal dynamics of microplastic distribution.Al Hoceima Marine protected areas exhibiting lower microplastic concentrations illustrate the eficacy of such zones in alleviating pollution impacts,thereby underscoring the signiicance of conservation efforts in safeguarding marine biodiversity and ecosystem resilience.Ultimately,our research enhances our comprehension of the pressures exerted by humans on marine environments and underscores the necessity of proactive conservation measures to shield marine ecosystems from the threats posed by microplastic pollution.
基金supported by a Discovery Early Career Researcher Award (DECRA,No.DE180101478) of the Australian Research CouncilNational Natural Science Foundation of China (Youth Program,No.52204378).
文摘Aqueous-electrolyte-based zinc-ion batteries(ZIBs),which have significant advantages over other batteries,including low cost,high safety,high ionic conductivity,and a natural abundance of zinc,have been regarded as a potential alternative to lithium-ion batteries(LIBs).ZIBs still face some critical challenges,however,especially for building a reversible zinc anode.To address the reversibility of zinc anode,great efforts have been made on intrinsic anode engineering and anode interface modification.Less attention has been devoted to the electrolyte additives,however,which could not only significantly improve the reversibility of zinc anode,but also determine the viability and overall performance of ZIBs.This review aims to provide an overview of the two main functions of electrolyte additives,followed by details on six reasons why additives might improve the performance of ZIBs from the perspectives of creating new layers and regulating current plating/stripping processes.Furthermore,the remaining difficulties and potential directions for additives in aqueous ZIBs are also highlighted.
