To evaluate the influence of various clinicopathologic factors on the survival of patients with bile duct carcinoma after curative resection Methods A retrospective analysis was performed on 86 cases of bile duct ca...To evaluate the influence of various clinicopathologic factors on the survival of patients with bile duct carcinoma after curative resection Methods A retrospective analysis was performed on 86 cases of bile duct carcinoma treated from January 1981 to September 1995 Fifteen clinicopathologic factors that could possibly influence survival were selected A multivariate analysis of these individuals was performed using the Cox Proportional Hazards Model Results The overall cumulative survival rate was 73% for 1 year, 32% for 3 years and 19% for 5 years The results of univariate analysis showed that the major significant prognostic factors for influencing survival of these patients were type of histological lesion, lymph node metastasis, pancreatic invasion, duodenal invasion, perineural invasion, macroscopic vessel involvement, resected surgical margin and depth of cancer invasion ( P 【0 05) Pancreatic invasion, perineural invasion and lymph node metastases were the three most important prognostic factors determined by multivariate analysis using the Cox Proportional Hazards Model Conclusion Pancreatic invasion, perineural invasion and lymph node metastases are the most important prognostic factors for bile duct carcinoma after curative resection展开更多
文摘To evaluate the influence of various clinicopathologic factors on the survival of patients with bile duct carcinoma after curative resection Methods A retrospective analysis was performed on 86 cases of bile duct carcinoma treated from January 1981 to September 1995 Fifteen clinicopathologic factors that could possibly influence survival were selected A multivariate analysis of these individuals was performed using the Cox Proportional Hazards Model Results The overall cumulative survival rate was 73% for 1 year, 32% for 3 years and 19% for 5 years The results of univariate analysis showed that the major significant prognostic factors for influencing survival of these patients were type of histological lesion, lymph node metastasis, pancreatic invasion, duodenal invasion, perineural invasion, macroscopic vessel involvement, resected surgical margin and depth of cancer invasion ( P 【0 05) Pancreatic invasion, perineural invasion and lymph node metastases were the three most important prognostic factors determined by multivariate analysis using the Cox Proportional Hazards Model Conclusion Pancreatic invasion, perineural invasion and lymph node metastases are the most important prognostic factors for bile duct carcinoma after curative resection
