In recent years,with the advancement of the Belt and Road Initiative,tourism cooperation has become closer between China and the countries along the Belt and Road.Statistics from the China Tourism Academy show that Ch...In recent years,with the advancement of the Belt and Road Initiative,tourism cooperation has become closer between China and the countries along the Belt and Road.Statistics from the China Tourism Academy show that China’s outbound tourists to the countries along the Belt and Road is on the rise from 15.49 million in 2013 to 27.41 million in 2017,up by 77%during five years and with an average annual growth rate of 15.34%.The development of tourism has boosted trade and cultural exchange between China and the countries along the Belt and Road,which has become a significant force in driving the construction of the Belt and Road.展开更多
President Xi Jinping’s inspection tour of Hebei to promote coordinated Beijing-Tianjin-Hebei development underlines the region’s pursuit of Chinese modernization.
Scientists from both life and earth sciences have invested generous efforts to investigate the evolutionary history and mechanism of microorganisms in deep time.One of the promising efforts may be inferring the optimu...Scientists from both life and earth sciences have invested generous efforts to investigate the evolutionary history and mechanism of microorganisms in deep time.One of the promising efforts may be inferring the optimum growth temperature(OGT)of microbial ancestors based on ancestral sequence reconstruction(ASR)(Gaucher et al.,2003).展开更多
Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase alle...Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase allele mining using six updated FNP marker systems,the functional haplotypes at Pit,Pib,and Pi63 strictly diverged into the X-populations and were defined as X-R loci,while those at Pi54,Pi37,and Pi36 into the G-populations as G-R loci.The genic diversity at the three X-R loci(16 alleles)was twofold higher than that at the three G-R loci(8 alleles),and the allelic diversity in the Southern region(21 alleles)was nearly double that in the Northeastern region(11 alleles).Both observations reflect a significant difference in genetic diversity between X-and G-populations,and indicate that the effective R-genes mainly originated from X-subspecies.Based on the allelic structures characterized by a set of 10 parameters,8 and 16 alleles were respectively recognized as favorable and promising ones for the regional breeding programs.The genotypic structures of the two regional populations were almost different,indicating that the diverged alleles have been further assembled into two series of regional genotypes through long-term breeding programs,despite the presence of one-third of region-common alleles.The genotypic diversity in the Southern region(55 genotypes)was nearly twice as high as that in the Northeastern region(28),which perfectly reflects the aforementioned differences in both genic and allelic diversities.After analyzing the genotypic structures using a set of 13 parameters,4 and 23 genotypes,respectively,can be recommended as the favorable and promising ones for the regional breeding programs.The case study serves as a concrete sample of how to identify the favorable and promising alleles and genotypes,and beneficial parents based their comprehensive population structures for gene-designed breeding.展开更多
Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau...Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.展开更多
In 2023,the China National Petroleum Corporation(CNPC)has successfully drilled a 10000-m ultra-deep well-TK-1 in the Tarim Basin,NW China.This pioneering project has achieved dual breakthroughs in ten-thousand-meter u...In 2023,the China National Petroleum Corporation(CNPC)has successfully drilled a 10000-m ultra-deep well-TK-1 in the Tarim Basin,NW China.This pioneering project has achieved dual breakthroughs in ten-thousand-meter ultra-deep earth science research and hydrocarbon exploration while driving technological advancements in ultra-deep well drilling engineering.The successful completion of TK-1 has yielded transformative geological discoveries.For the first time in exploration history,comprehensive data including cores,well logs,fluids,temperature and pressure were obtained from 10000-meter depths.These findings conclusively demonstrate the existence of effective source rocks,carbonate reservoirs,and producible conventional hydrocarbons at such extreme depths-fundamentally challenging established petroleum geology paradigms.The results not only confirm the enormous hydrocarbon potential of ultra-deep formations in the Tarim Basin but also identify the most promising exploration targets.From an engineering perspective,the project has established four groundbreaking technological systems:safe drilling in complex pressure systems of ultra-deep wells,optimized and fast drilling in complex and difficult-to-drill formations of ultra-deep wells,wellbore quality control under harsh conditions in ultra-deep wells,and data acquisition in ultra-deep,ultra-high-temperature complex formations.Additionally,ten key tools for ultra-deep well drilling and completion engineering were developed,enabling the successful completion of Asia’s first and the world’s second-deepest vertical well.This achievement has significantly advanced the understanding of geological conditions at depths exceeding 10000 m and positioned China as one of the few countries with core technologies for ultra-deep well drilling.展开更多
1.Introduction Phase Ⅱ trials are typically designed to identify promising treatment therapies that warrant further investigation in subsequent phase Ⅲ con-firmatory trials,playing a vital role in evidence generatio...1.Introduction Phase Ⅱ trials are typically designed to identify promising treatment therapies that warrant further investigation in subsequent phase Ⅲ con-firmatory trials,playing a vital role in evidence generation of drug de-velopment.The basic design features of phase II trials include interim go/no-go decisions to prevent exposing too many patients to poten-tially ineffective treatments.Appropriate go/no-go decisions and effi-cient trial designs can shorten the research duration and increase trial success rates.展开更多
U.S. vice president’s visit to China boosts mutual confidence despite economic concerns U.S. Vice President Joe Biden’s recent visit to China helped strengthen relations between the two powers,
AT dusk, I switched on my radio. What I heard was a special call-in program entitled "New Air of the City," on a local music channel; the two silver-tongued hosts were discussing the topic of promises. A you...AT dusk, I switched on my radio. What I heard was a special call-in program entitled "New Air of the City," on a local music channel; the two silver-tongued hosts were discussing the topic of promises. A young woman with a soft voice managed to get through first. She said that she had been in love for many years. She and her fiance often went to the banks of the Yangtze River in their spare time, lifting stones to look for small crabs, as tiny as fingernails. They liked to raise the crabs in a glass bowl. But one day, there were few stones by the river; they searched for a long time, but found nothing. An old man who was catching fish told them that it was difficult to find those crabs on the bank. Then he took several crabs out of展开更多
AT the closing ceremony of the UN Fourth World Conference on Women, Mme. Peng Peiyun, Chinese State Councilor, said, "I believe that this Conference will become a starting point of the worldwide women’s cause. T...AT the closing ceremony of the UN Fourth World Conference on Women, Mme. Peng Peiyun, Chinese State Councilor, said, "I believe that this Conference will become a starting point of the worldwide women’s cause. The effect of the Conference depends展开更多
Will artificial intelligence(AI)replace my job?This is a question that lingers in the minds of many these days.Similar concerns surfaced a couple of years ago when said technology narrowly defeated a champion of the g...Will artificial intelligence(AI)replace my job?This is a question that lingers in the minds of many these days.Similar concerns surfaced a couple of years ago when said technology narrowly defeated a champion of the game Go.At present,the application of AI robotics in a range of professional fields,as well as ChatGPT's abilities to write essays,solve complex problems,compose song lyrics,do school homework,and more,have heightened moral concerns.展开更多
文摘In recent years,with the advancement of the Belt and Road Initiative,tourism cooperation has become closer between China and the countries along the Belt and Road.Statistics from the China Tourism Academy show that China’s outbound tourists to the countries along the Belt and Road is on the rise from 15.49 million in 2013 to 27.41 million in 2017,up by 77%during five years and with an average annual growth rate of 15.34%.The development of tourism has boosted trade and cultural exchange between China and the countries along the Belt and Road,which has become a significant force in driving the construction of the Belt and Road.
文摘President Xi Jinping’s inspection tour of Hebei to promote coordinated Beijing-Tianjin-Hebei development underlines the region’s pursuit of Chinese modernization.
基金supported by the National Natural Science Foundation of China(Grant Nos.92351301&32393974)。
文摘Scientists from both life and earth sciences have invested generous efforts to investigate the evolutionary history and mechanism of microorganisms in deep time.One of the promising efforts may be inferring the optimum growth temperature(OGT)of microbial ancestors based on ancestral sequence reconstruction(ASR)(Gaucher et al.,2003).
基金funded by grants from the National Key R&D Project(2023YFD1400201-02,2023YFD1400203-02)the National Natural Science Foundation of China(31870137)+1 种基金the National Transgenic Research Project(2015ZX08001-002)the Key R&D Project of Guangdong Province(2022B0202060005).
文摘Asian rice comprises two major subspecies:Xian(X)and Geng(G),and the diverged resistance genes(R)have provided a foundation for breeding improved cultivars to control rice blast disease.After conducting two-phase allele mining using six updated FNP marker systems,the functional haplotypes at Pit,Pib,and Pi63 strictly diverged into the X-populations and were defined as X-R loci,while those at Pi54,Pi37,and Pi36 into the G-populations as G-R loci.The genic diversity at the three X-R loci(16 alleles)was twofold higher than that at the three G-R loci(8 alleles),and the allelic diversity in the Southern region(21 alleles)was nearly double that in the Northeastern region(11 alleles).Both observations reflect a significant difference in genetic diversity between X-and G-populations,and indicate that the effective R-genes mainly originated from X-subspecies.Based on the allelic structures characterized by a set of 10 parameters,8 and 16 alleles were respectively recognized as favorable and promising ones for the regional breeding programs.The genotypic structures of the two regional populations were almost different,indicating that the diverged alleles have been further assembled into two series of regional genotypes through long-term breeding programs,despite the presence of one-third of region-common alleles.The genotypic diversity in the Southern region(55 genotypes)was nearly twice as high as that in the Northeastern region(28),which perfectly reflects the aforementioned differences in both genic and allelic diversities.After analyzing the genotypic structures using a set of 13 parameters,4 and 23 genotypes,respectively,can be recommended as the favorable and promising ones for the regional breeding programs.The case study serves as a concrete sample of how to identify the favorable and promising alleles and genotypes,and beneficial parents based their comprehensive population structures for gene-designed breeding.
文摘Rainbows-symbolizing peace,hope,promise and endurance(忍耐力)in hard times-are springing up in neighborhoods throughout Long Island in an effort to color the future road with optimism.The campaign,Rainbows over Nassau and Suffolk Counties and Beyond,started on March 21 and spread through a group.It's a campaign that encourages participants to make rainbows to display outside their homes,anywhere from their front windows and doors to lawns and sidewalks.It follows another similar project,Chalk Your Walk,which promotes writing hopeful messages in chalk on driveways and sidewalks.
文摘In 2023,the China National Petroleum Corporation(CNPC)has successfully drilled a 10000-m ultra-deep well-TK-1 in the Tarim Basin,NW China.This pioneering project has achieved dual breakthroughs in ten-thousand-meter ultra-deep earth science research and hydrocarbon exploration while driving technological advancements in ultra-deep well drilling engineering.The successful completion of TK-1 has yielded transformative geological discoveries.For the first time in exploration history,comprehensive data including cores,well logs,fluids,temperature and pressure were obtained from 10000-meter depths.These findings conclusively demonstrate the existence of effective source rocks,carbonate reservoirs,and producible conventional hydrocarbons at such extreme depths-fundamentally challenging established petroleum geology paradigms.The results not only confirm the enormous hydrocarbon potential of ultra-deep formations in the Tarim Basin but also identify the most promising exploration targets.From an engineering perspective,the project has established four groundbreaking technological systems:safe drilling in complex pressure systems of ultra-deep wells,optimized and fast drilling in complex and difficult-to-drill formations of ultra-deep wells,wellbore quality control under harsh conditions in ultra-deep wells,and data acquisition in ultra-deep,ultra-high-temperature complex formations.Additionally,ten key tools for ultra-deep well drilling and completion engineering were developed,enabling the successful completion of Asia’s first and the world’s second-deepest vertical well.This achievement has significantly advanced the understanding of geological conditions at depths exceeding 10000 m and positioned China as one of the few countries with core technologies for ultra-deep well drilling.
基金funded by Beijing Nova Program(grant number:20230484277)National Natural Science Foundation of China(grant number:82303955).
文摘1.Introduction Phase Ⅱ trials are typically designed to identify promising treatment therapies that warrant further investigation in subsequent phase Ⅲ con-firmatory trials,playing a vital role in evidence generation of drug de-velopment.The basic design features of phase II trials include interim go/no-go decisions to prevent exposing too many patients to poten-tially ineffective treatments.Appropriate go/no-go decisions and effi-cient trial designs can shorten the research duration and increase trial success rates.
文摘Authorities have released a list of essential medicines to lower costs and ensure access for all china’s Health Ministry released a list of essential
文摘U.S. vice president’s visit to China boosts mutual confidence despite economic concerns U.S. Vice President Joe Biden’s recent visit to China helped strengthen relations between the two powers,
文摘AT dusk, I switched on my radio. What I heard was a special call-in program entitled "New Air of the City," on a local music channel; the two silver-tongued hosts were discussing the topic of promises. A young woman with a soft voice managed to get through first. She said that she had been in love for many years. She and her fiance often went to the banks of the Yangtze River in their spare time, lifting stones to look for small crabs, as tiny as fingernails. They liked to raise the crabs in a glass bowl. But one day, there were few stones by the river; they searched for a long time, but found nothing. An old man who was catching fish told them that it was difficult to find those crabs on the bank. Then he took several crabs out of
文摘AT the closing ceremony of the UN Fourth World Conference on Women, Mme. Peng Peiyun, Chinese State Councilor, said, "I believe that this Conference will become a starting point of the worldwide women’s cause. The effect of the Conference depends
文摘Will artificial intelligence(AI)replace my job?This is a question that lingers in the minds of many these days.Similar concerns surfaced a couple of years ago when said technology narrowly defeated a champion of the game Go.At present,the application of AI robotics in a range of professional fields,as well as ChatGPT's abilities to write essays,solve complex problems,compose song lyrics,do school homework,and more,have heightened moral concerns.
