The new double projecting neurons were found in the cat spinal dorsal horn by the double retrograde fluorescent tracing technique.Fast Blue(FB)was injected into unilateral dorsal column nucleus(DCN)of adult cats anest...The new double projecting neurons were found in the cat spinal dorsal horn by the double retrograde fluorescent tracing technique.Fast Blue(FB)was injected into unilateral dorsal column nucleus(DCN)of adult cats anesthetized with pentobarbital.Nuclear Yellow(NY)was injected ipsilaterally into the lateral cervical nucleus(LCN)8-9 days later.After an additional 18-30 hrs.展开更多
Coded structured light is an accurate, fast 3D measurement approach with high sampling density, of which the encoded fringes are distorted when projected to curved surface. Focused on the demand of encoding, decoding,...Coded structured light is an accurate, fast 3D measurement approach with high sampling density, of which the encoded fringes are distorted when projected to curved surface. Focused on the demand of encoding, decoding, multiview registration and system calibration, we expect to obtain undistorted fringes from camera image. Therefore, in this paper, we analyze the accuracy and sampling density of projecting distortion calibration approach based on control point and fitting surface. Moreover, combining the characteristic of coded structured light system, we design encoded fringe projecting distortion calibration scheme based on simplified encoded structured light model. Primarily, we neglect the minor parameters that affect the calibration in structured light model to reduce complexity. Then, we build the correspondence between camera image points and projector image points and achieve the calibration. Finally, we design evaluation scheme of projecting distortion calibration with parallelism and equal interval, and verify the effectiveness and accuracy of the approach through visual effect and experimental data.展开更多
Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate model...Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate models(GCMs) are subject to considerable uncertainties, largely caused by their coarse resolution. This study applies a triple-nested WRF(Weather Research and Forecasting) model dynamical downscaling, driven by a GCM, MIROC6(Model for Interdisciplinary Research on Climate, version 6), to improve the historical simulation and reduce the uncertainties in the future projection of CREs in the TGR. Results indicate that WRF has better performances in reproducing the observed rainfall in terms of the daily probability distribution, monthly evolution and duration of rainfall events, demonstrating the ability of WRF in simulating CREs. Thus, the triple-nested WRF is applied to project the future changes of CREs under the middle-of-the-road and fossil-fueled development scenarios. It is indicated that light and moderate rainfall and the duration of continuous rainfall spells will decrease in the TGR, leading to a decrease in the frequency of CREs. Meanwhile, the duration, rainfall amount, and intensity of CREs is projected to regional increase in the central-west TGR. These results are inconsistent with the raw projection of MIROC6. Observational diagnosis implies that CREs are mainly contributed by the vertical moisture advection. Such a synoptic contribution is captured well by WRF, which is not the case in MIROC6,indicating larger uncertainties in the CREs projected by MIROC6.展开更多
Since no consensus has been reached in previous studies about how the summer climate in China will evolve in the first half of the 21st century, this issue is addressed here through sensitivity experiments by forcing ...Since no consensus has been reached in previous studies about how the summer climate in China will evolve in the first half of the 21st century, this issue is addressed here through sensitivity experiments by forcing an atmospheric general circulation model （AGCM）, the Geophysical Fluid Dynamics Laboratory （GFDL）＇s Atmospheric Model Version 2.0 （AM2） with projected sea surface temperature （SST） trend. A total of two SST trends from the Intergovernmental Panels on Climate Change （IPCC） Special Report on Emissions Scenario （SRES） AlB are used. The two trends are from two coupled climate system models, the National Center for Atmospheric Research （NCAR） Community Climate System Model Version 3.0 （CCSM3） and the GFDL Climate Model Version 2.0 （CM2）, respectively. Results consistently suggest a substantial warming and drying trend over much of China, with a surface air temperature increase of 1.0-2.0℃ and a 10%-20% decrease in rainfall. Exceptions are the areas from northwestern China to western North China as well as the southern Tibetan Plateau, which are projected to be wetter with a rainfall anomaly percentage increase of 10%-50%. The drying in eastern North China has not been documented to date but appears to be reasonable. Physically, it is attributed to anomalous northeasterly winds at the rear of a low-level cyclone over the South China Sea, the Philippines and the subtropical western North Pacific. These conditions, which govern the climate of eastern China, are forced by the northward shift of convection over warm waters due to additional warming.展开更多
The neurons with coexistence of serotonin-and giutamate-immunoreactivity(5-HT/Glu cells)in medullary raphe nuclei were investigated in the present study by using immunofluorescence technique.On the basis or the invest...The neurons with coexistence of serotonin-and giutamate-immunoreactivity(5-HT/Glu cells)in medullary raphe nuclei were investigated in the present study by using immunofluorescence technique.On the basis or the investigation projections of the 5-HT/Glu cells to the cerebellar cortex were studied by means or a combined microsphere retrograde transport.The results showed that most of the 5-HT cells in medullary raphe nuclei exhibited Glu-immunoreactivity.The cell count indicated that 81.77% of the 5-HT cells contained Gin-immunoreactivity;40.35%of the Gin-cells contained 5-HT.The retrograde labeled cells by microspkere(MS cells)were found in all medullary rapke nuclei. 5-HT/MS cells were rare.The Gin/MS cells had a rate in total MS cells(40.31 %).Three trible-labeled cells (5-HT/Glu/MS cells)were found. The finding or the 5-HT/Glu cells in medullary raphe nuclei projecting to the cerebellar cortex may give an iportant significance to understanding the functional connection between medullary raphe nuclei and cerebellum.展开更多
Detailed projections of the Former Soviet Union(FSU)fossil fuel production has been created.Russian production has been modelled at the region(oblast)level where possible.The projections were made using the Geologic R...Detailed projections of the Former Soviet Union(FSU)fossil fuel production has been created.Russian production has been modelled at the region(oblast)level where possible.The projections were made using the Geologic Resource Supply-Demand Model(GeRS-DeMo).Low,Best Guess and High scenarios were created.FSU fossil fuels are projected to peak between 2027 and 2087 with the range due to spread of Ultimately Recoverable Resources(URR)values used.The Best Guess(BG)scenario anticipates FSU will peak in 2087 with production over 170 EJ per year.The FSU projections were combined with rest of the world projections(Mohr et al.2015b),the emissions from the High scenario for the world are similar to the IPCC A1 AIM scenario.展开更多
Objectives: To project health outcomes for the period 2011-2031, in the Portuguese population aged 65 years and over, considering the expected changes in its demographic and educational structure. Methods: Demographic...Objectives: To project health outcomes for the period 2011-2031, in the Portuguese population aged 65 years and over, considering the expected changes in its demographic and educational structure. Methods: Demographic projections were produced using the multistate cohort component method. Logistic regression models were fitted to estimate current differences in health outcomes, using data from the Portuguese Health Survey. Such differences were applied to the projection results, in order to project the prevalence of “poor” self-reported health status, functional limitations and disability. Results: Our results point to a future improvement in the considered health outcomes. The prevalence of “poor” self-reported health status, functional limitations and disability will decrease in both genders, but will continue to be higher among women than men. Discussion: Beyond age and gender, other determinants of health, like education, should be considered when studying the possible evolution of health outcomes in an ageing population.展开更多
Climate models are essential for understanding past,present,and future changes in atmospheric circulation,with circulation modes providing key sources of seasonal predictability and prediction uncertainties for both g...Climate models are essential for understanding past,present,and future changes in atmospheric circulation,with circulation modes providing key sources of seasonal predictability and prediction uncertainties for both global and regional climates.This study assesses the performance of models participating in phase 6 of the Coupled Model Intercomparison Project in simulating interannual variability modes of Northern Hemisphere 500-hPa geopotential height during winter and summer,distinguishing predictable(potentially predictable on seasonal or longer timescales)and unpredictable(intraseasonal and essentially unpredictable at long range)components,using reanalysis data and a variance decomposition method.Although most models effectively capture unpredictable modes in reanalysis,their ability to reproduce dominant predictable modes-specifically the Pacific-North American pattern,Arctic Oscillation,and Western Pacific Oscillation in winter,and the East Atlantic and North Atlantic Oscillations in summer-varies notably.An optimal ensemble is identified to distinguish(a)predictable-external modes,dominated by external forcing,and(b)predictable-internal modes,associated with slow internal variability,during the historical period(1950-2014)and the SSP5-8.5 scenario(2036-2100).Under increased radiative forcing,the leading winter/summer predictable-external mode exhibits a more uniform spatial distribution,remarkably larger trend and annual variance,and enhanced height-sea surface temperature(SST)covariance under SSP5-8.5 compared to historical conditions.The dominant winter/summer predictable-internal modes also exhibit increased variance and height-SST covariance under SSP5-8.5,along with localized changes in spatial configuration.Minimal changes are observed in spatial distribution or variance for dominant winter/summer unpredictable modes under SSP5-8.5.This study,from a predictive perspective,deepens our understanding of model uncertainties and projected changes in circulations.展开更多
Andrew Wangota,a 48-year-old Ugandan farmer,has been using agrivoltaics technology,a solar technology that uses agricultural land for both food production and solar power generation,on his farm in Bunashimolo Parish,B...Andrew Wangota,a 48-year-old Ugandan farmer,has been using agrivoltaics technology,a solar technology that uses agricultural land for both food production and solar power generation,on his farm in Bunashimolo Parish,Bukyiende Subcounty in Uganda where he has been cultivating plantain,coffee and Irish potatoes for the past 16 years.展开更多
Global warming induced by increased CO_(2) has caused marked changes in the ocean.Previous estimates of ocean salinity change in response to global warming have considerable ambiguity,largely attributable to the diver...Global warming induced by increased CO_(2) has caused marked changes in the ocean.Previous estimates of ocean salinity change in response to global warming have considerable ambiguity,largely attributable to the diverse sensitivities of surface fluxes.This study utilizes data from the Flux-Anomaly-Forced Model Intercomparison Project to investigate how ocean salinity responds to perturbations of surface fluxes.The findings indicate the emergence of a sea surface salinity(SSS)dipole pattern predominantly in the North Atlantic and Pacific fresh pools,driven by surface flux perturbations.This results in an intensification of the“salty gets saltier and fresh gets fresher”SSS pattern across the global ocean.The spatial pattern amplification(PA)of SSS under global warming is estimated to be approximately 11.5%,with surface water flux perturbations being the most significant contributor to salinity PA,accounting for 8.1% of the change after 70 years in experiments since pre-industrial control(piControl).Notably,the zonal-depth distribution of salinity in the upper ocean exhibits lighter seawater above the denser water,with bowed isopycnals in the upper 400 m.This stable stratification inhibits vertical mixing of salinity and temperature.In response to the flux perturbations,there is a strong positive feedback due to consequent freshening.It is hypothesized that under global warming,an SSS amplification of 7.2%/℃ and a mixed-layer depth amplification of 12.5%/℃ will occur in the global ocean.It suggests that the salinity effect can exert a more stable ocean to hinder the downward transfer of heat,which provides positive feedback to future global warming.展开更多
The global monsoon system,encompassing the Asian-Australian,African,and American monsoons,sustains two-thirds of the world’s population by regulating water resources and agriculture.Monsoon anomalies pose severe risk...The global monsoon system,encompassing the Asian-Australian,African,and American monsoons,sustains two-thirds of the world’s population by regulating water resources and agriculture.Monsoon anomalies pose severe risks,including floods and droughts.Recent research associated with the implementation of the Global Monsoons Model Intercomparison Project under the umbrella of CMIP6 has advanced our understanding of its historical variability and driving mechanisms.Observational data reveal a 20th-century shift:increased rainfall pre-1950s,followed by aridification and partial recovery post-1980s,driven by both internal variability(e.g.,Atlantic Multidecadal Oscillation)and external forcings(greenhouse gases,aerosols),while ENSO drives interannual variability through ocean-atmosphere interactions.Future projections under greenhouse forcing suggest long-term monsoon intensification,though regional disparities and model uncertainties persist.Models indicate robust trends but struggle to quantify extremes,where thermodynamic effects(warming-induced moisture rise)uniformly boost heavy rainfall,while dynamical shifts(circulation changes)create spatial heterogeneity.Volcanic eruptions and proposed solar radiation modification(SRM)further complicate predictions:tropical eruptions suppress monsoons,whereas high-latitude events alter cross-equatorial flows,highlighting unresolved feedbacks.The emergent constraint approach is booming in terms of correcting future projections and reducing uncertainty with respect to the global monsoons.Critical challenges remain.Model biases and sparse 20th-century observational data hinder accurate attribution.The interplay between natural variability and anthropogenic forcings,along with nonlinear extreme precipitation risks under warming,demands deeper mechanistic insights.Additionally,SRM’s regional impacts and hemispheric monsoon interactions require systematic evaluation.Addressing these gaps necessitates enhanced observational networks,refined climate models,and interdisciplinary efforts to disentangle multiscale drivers,ultimately improving resilience strategies for monsoon-dependent regions.展开更多
The 2008 Olympic Games in Beijing will provide a good opportunity to boost China’s public relations industry It seems like an impossible mission to enable a foreigner to experience China’s 5,000-year history in just...The 2008 Olympic Games in Beijing will provide a good opportunity to boost China’s public relations industry It seems like an impossible mission to enable a foreigner to experience China’s 5,000-year history in just a few hours,but Mark Zhou, a Chinese, and Alex Koi, a Singaporean, have done just that.In an effort to enable people to get to know China, they have launched “urban safari” activities, in which the participants in a simulated environment can enjoy all kinds of food, videotapes and a detailed explanation to get an intimate feel of China’s history, culture, arts and folk customs in just six hours.展开更多
The onset,cessation,and length of the rainy season are crucial for global water resources,agricultural practices,and food security.However,the response of precipitation seasonality to global warming remains uncertain....The onset,cessation,and length of the rainy season are crucial for global water resources,agricultural practices,and food security.However,the response of precipitation seasonality to global warming remains uncertain.In this study,we analyze how global warming levels(GWLs)of 1.5℃ and 2℃ could affect the timing of rainfall onset(RODs),rainfall cessation(RCDs),and the overall duration of the rainy season(LRS)over global land monsoon(GLM)regions using simulations from CMIP6 under the SSP2-4.5 and SSP5-8.5 scenarios.With high model consensus,our results reveal that RODs are projected to occur later over Southern Africa,North Africa,and South America,but earlier over South Asia and Australia,in a warmer climate.The projected early RODs in Australia are more pronounced at the 2℃ GWL under SSP5-8.5.On the other hand,early RCDs are projected over South America and East Asia,while late RCDs are projected over North Africa,with high inter-model agreement.These changes are associated with a future decrease in LRS in most GLM regions.Additionally,we found that continuous warming over 1.5℃ will further reduce the length of the rainy season,especially over the South America,North Africa,and Southern Africa monsoon regions.The findings underscore the urgent need to mitigate global warming.展开更多
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(...Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].展开更多
Considering the importance of black carbon （BC）, this study began by comparing the 20th century simulation of South Asian summer climate in IPCC CMIP3, based on the scenario of models with and without BC. Generally,...Considering the importance of black carbon （BC）, this study began by comparing the 20th century simulation of South Asian summer climate in IPCC CMIP3, based on the scenario of models with and without BC. Generally, the multi-model mean of the models that include BC reproduced the observed climate relatively better than those that did not. Then, the 21st century South Asian summer precipitation was projected based on the IPCC CMIP3 projection simulations. The projected precipitation in the present approach exhibited a considerable difference from the multi- model ensemble mean （MME） of IPCC AR4 projection simulations, and also from the MME of the models that ig- nore the effect of BC. In particular, the present projection exhibited a dry anomaly over the central Indian Peninsula, sandwiched between wet conditions on the southern and northern sides of Pakistan and India, rather than homogen- eous wet conditions as seen in the MME of IPCC AR4. Thus, the spatial pattern of South Asian summer rainfall in the future may be more complicated than previously thought.展开更多
Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical ca...Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical cancer as a major public health problem.Methods All data were extracted from the Global Cancer Observatory(GLOBOCAN)2022.Age-standardized incidence rate(ASIR)and mortality rates(ASMR)of cervical cancer were compared and linked to Human Development Index(HDI)between populations.The estimated annual percentage changes(EAPCs)were used to characterize the temporal trend in ASIR/ASMR,and demographic estimates were projected up to 2050.Results Globally,an estimated 662,044 cases(ASIR:14.12/100,000)and 348,709 deaths(ASMR:7.08/100,000)from cervical cancer occurred in 2022,corresponding to the fourth cause of cancer morbidity and mortality in women worldwide.Specifically,42%of cases and 39%of deaths occurred in China(23%and 16%)and India(19%and 23%).Both ASIR and ASMR of cervical cancer decreased with HDI,and similar decreasing links were observed for both early-onset(0–39 years)and late-onset(≥40 years)cervical cancer.Both ASIR and ASMR of overall cervical cancer showed decreasing trends during 2003–2012(EAPC:0.04%and-1.03%);however,upward trends were observed for early-onset cervical cancer(EAPC:1.16%and 0.57%).If national rates in 2022 remain stable,the estimated cases and deaths from cervical cancer are projected to increase by 56.8%and 80.7%up to 2050.Moreover,the projected increase of early-onset cervical cancer is mainly observed in transitioning countries,while decreased burden is expected in transitioned countries.Conclusions Cervical cancer remains a common cause of cancer death in many countries,especially in transitioning countries.Unless scaling-up preventive interventions,human papillomavirus(HPV)vaccination and cervical cancer screening,as well as systematic cooperation within government,civil societies,and private enterprises,the global burden of cervical cancer would be expected to increase in the future.展开更多
Within the framework of the 2030 Agenda and to achieve the Sustainable Development Goals(SDGs),science,technology and innovation play an even more central role.Building on this foundation,the primary objective of this...Within the framework of the 2030 Agenda and to achieve the Sustainable Development Goals(SDGs),science,technology and innovation play an even more central role.Building on this foundation,the primary objective of this paper is to explore the potential applications of blockchain in supporting the achievement of these sustainability goals.Starting from a review of the relevant literature on this topic,the main fields in which blockchain can contribute to sustainable development will be identified.The main blockchain applications will then be analyzed and categorized according to these SDGs.This research will then critically present the main blockchain-based projects that emerged in the first stage of the study and were implemented by the United Nations.The main objectives and benefits of each project will be analyzed.This is where the originality of this paper lies.To the best of the author’s knowledge,this is one of the first attempts to present a comprehensive overview of the United Nations’projects related to SDGs 1,2,5,7,9,13,and 16.This paper,which bridges the gap between innovation management and the sustainability field,will contribute to the increasingly current debate on sustainability issues and be beneficial to scholars,practitioners,and policymakers alike.展开更多
文摘The new double projecting neurons were found in the cat spinal dorsal horn by the double retrograde fluorescent tracing technique.Fast Blue(FB)was injected into unilateral dorsal column nucleus(DCN)of adult cats anesthetized with pentobarbital.Nuclear Yellow(NY)was injected ipsilaterally into the lateral cervical nucleus(LCN)8-9 days later.After an additional 18-30 hrs.
基金The support of National Science Foundation of China (61571168,61401126), Leading Talent Team Backup Leader Foundation of Heilongjiang Province are gratefully acknowledged.
文摘Coded structured light is an accurate, fast 3D measurement approach with high sampling density, of which the encoded fringes are distorted when projected to curved surface. Focused on the demand of encoding, decoding, multiview registration and system calibration, we expect to obtain undistorted fringes from camera image. Therefore, in this paper, we analyze the accuracy and sampling density of projecting distortion calibration approach based on control point and fitting surface. Moreover, combining the characteristic of coded structured light system, we design encoded fringe projecting distortion calibration scheme based on simplified encoded structured light model. Primarily, we neglect the minor parameters that affect the calibration in structured light model to reduce complexity. Then, we build the correspondence between camera image points and projector image points and achieve the calibration. Finally, we design evaluation scheme of projecting distortion calibration with parallelism and equal interval, and verify the effectiveness and accuracy of the approach through visual effect and experimental data.
基金funding from the NFR COMBINED (Grant No.328935)The BCPU hosted YZ visit to University of Bergen (Trond Mohn Foundation Grant No.BFS2018TMT01)+2 种基金supported by the National Key Research and Development Program of China (Grant No.2023YFA0805101)the National Natural Science Foundation of China (Grant Nos.42376250 and 41731177)a China Scholarship Council fellowship and the UTFORSK Partnership Program (CONNECTED UTF-2016-long-term/10030)。
文摘Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate models(GCMs) are subject to considerable uncertainties, largely caused by their coarse resolution. This study applies a triple-nested WRF(Weather Research and Forecasting) model dynamical downscaling, driven by a GCM, MIROC6(Model for Interdisciplinary Research on Climate, version 6), to improve the historical simulation and reduce the uncertainties in the future projection of CREs in the TGR. Results indicate that WRF has better performances in reproducing the observed rainfall in terms of the daily probability distribution, monthly evolution and duration of rainfall events, demonstrating the ability of WRF in simulating CREs. Thus, the triple-nested WRF is applied to project the future changes of CREs under the middle-of-the-road and fossil-fueled development scenarios. It is indicated that light and moderate rainfall and the duration of continuous rainfall spells will decrease in the TGR, leading to a decrease in the frequency of CREs. Meanwhile, the duration, rainfall amount, and intensity of CREs is projected to regional increase in the central-west TGR. These results are inconsistent with the raw projection of MIROC6. Observational diagnosis implies that CREs are mainly contributed by the vertical moisture advection. Such a synoptic contribution is captured well by WRF, which is not the case in MIROC6,indicating larger uncertainties in the CREs projected by MIROC6.
基金supported by the National Natural Science Foundation of China under Grant Nos. 90711004 and 40775053"One Hundred Talent Plan" of the Chinese Academy of Sciences
文摘Since no consensus has been reached in previous studies about how the summer climate in China will evolve in the first half of the 21st century, this issue is addressed here through sensitivity experiments by forcing an atmospheric general circulation model （AGCM）, the Geophysical Fluid Dynamics Laboratory （GFDL）＇s Atmospheric Model Version 2.0 （AM2） with projected sea surface temperature （SST） trend. A total of two SST trends from the Intergovernmental Panels on Climate Change （IPCC） Special Report on Emissions Scenario （SRES） AlB are used. The two trends are from two coupled climate system models, the National Center for Atmospheric Research （NCAR） Community Climate System Model Version 3.0 （CCSM3） and the GFDL Climate Model Version 2.0 （CM2）, respectively. Results consistently suggest a substantial warming and drying trend over much of China, with a surface air temperature increase of 1.0-2.0℃ and a 10%-20% decrease in rainfall. Exceptions are the areas from northwestern China to western North China as well as the southern Tibetan Plateau, which are projected to be wetter with a rainfall anomaly percentage increase of 10%-50%. The drying in eastern North China has not been documented to date but appears to be reasonable. Physically, it is attributed to anomalous northeasterly winds at the rear of a low-level cyclone over the South China Sea, the Philippines and the subtropical western North Pacific. These conditions, which govern the climate of eastern China, are forced by the northward shift of convection over warm waters due to additional warming.
文摘The neurons with coexistence of serotonin-and giutamate-immunoreactivity(5-HT/Glu cells)in medullary raphe nuclei were investigated in the present study by using immunofluorescence technique.On the basis or the investigation projections of the 5-HT/Glu cells to the cerebellar cortex were studied by means or a combined microsphere retrograde transport.The results showed that most of the 5-HT cells in medullary raphe nuclei exhibited Glu-immunoreactivity.The cell count indicated that 81.77% of the 5-HT cells contained Gin-immunoreactivity;40.35%of the Gin-cells contained 5-HT.The retrograde labeled cells by microspkere(MS cells)were found in all medullary rapke nuclei. 5-HT/MS cells were rare.The Gin/MS cells had a rate in total MS cells(40.31 %).Three trible-labeled cells (5-HT/Glu/MS cells)were found. The finding or the 5-HT/Glu cells in medullary raphe nuclei projecting to the cerebellar cortex may give an iportant significance to understanding the functional connection between medullary raphe nuclei and cerebellum.
基金The authors wish to thank:Igor Kharitonov,Director,Department for Foreign Statistics and International Projects,Federal State Statistics Service,Rosstat.State Statistics Service,Main Department of Statistics in Donetsk Oblast.The Ukrainian Statistical agency UkrStat.gov.ua.
文摘Detailed projections of the Former Soviet Union(FSU)fossil fuel production has been created.Russian production has been modelled at the region(oblast)level where possible.The projections were made using the Geologic Resource Supply-Demand Model(GeRS-DeMo).Low,Best Guess and High scenarios were created.FSU fossil fuels are projected to peak between 2027 and 2087 with the range due to spread of Ultimately Recoverable Resources(URR)values used.The Best Guess(BG)scenario anticipates FSU will peak in 2087 with production over 170 EJ per year.The FSU projections were combined with rest of the world projections(Mohr et al.2015b),the emissions from the High scenario for the world are similar to the IPCC A1 AIM scenario.
文摘Objectives: To project health outcomes for the period 2011-2031, in the Portuguese population aged 65 years and over, considering the expected changes in its demographic and educational structure. Methods: Demographic projections were produced using the multistate cohort component method. Logistic regression models were fitted to estimate current differences in health outcomes, using data from the Portuguese Health Survey. Such differences were applied to the projection results, in order to project the prevalence of “poor” self-reported health status, functional limitations and disability. Results: Our results point to a future improvement in the considered health outcomes. The prevalence of “poor” self-reported health status, functional limitations and disability will decrease in both genders, but will continue to be higher among women than men. Discussion: Beyond age and gender, other determinants of health, like education, should be considered when studying the possible evolution of health outcomes in an ageing population.
基金supported by the National Natural Science Foundation of China(Grant Nos.U2342210 and 42275043)the National Institute of Natural Hazards,Ministry of Emergency Management of China(Grant Nos.J2223806,ZDJ2024-25 and ZDJ2025-34)。
文摘Climate models are essential for understanding past,present,and future changes in atmospheric circulation,with circulation modes providing key sources of seasonal predictability and prediction uncertainties for both global and regional climates.This study assesses the performance of models participating in phase 6 of the Coupled Model Intercomparison Project in simulating interannual variability modes of Northern Hemisphere 500-hPa geopotential height during winter and summer,distinguishing predictable(potentially predictable on seasonal or longer timescales)and unpredictable(intraseasonal and essentially unpredictable at long range)components,using reanalysis data and a variance decomposition method.Although most models effectively capture unpredictable modes in reanalysis,their ability to reproduce dominant predictable modes-specifically the Pacific-North American pattern,Arctic Oscillation,and Western Pacific Oscillation in winter,and the East Atlantic and North Atlantic Oscillations in summer-varies notably.An optimal ensemble is identified to distinguish(a)predictable-external modes,dominated by external forcing,and(b)predictable-internal modes,associated with slow internal variability,during the historical period(1950-2014)and the SSP5-8.5 scenario(2036-2100).Under increased radiative forcing,the leading winter/summer predictable-external mode exhibits a more uniform spatial distribution,remarkably larger trend and annual variance,and enhanced height-sea surface temperature(SST)covariance under SSP5-8.5 compared to historical conditions.The dominant winter/summer predictable-internal modes also exhibit increased variance and height-SST covariance under SSP5-8.5,along with localized changes in spatial configuration.Minimal changes are observed in spatial distribution or variance for dominant winter/summer unpredictable modes under SSP5-8.5.This study,from a predictive perspective,deepens our understanding of model uncertainties and projected changes in circulations.
文摘Andrew Wangota,a 48-year-old Ugandan farmer,has been using agrivoltaics technology,a solar technology that uses agricultural land for both food production and solar power generation,on his farm in Bunashimolo Parish,Bukyiende Subcounty in Uganda where he has been cultivating plantain,coffee and Irish potatoes for the past 16 years.
基金supported by the Laoshan Laboratory[grant number LSKJ202202403]the National Natural Science Foundation of China[grant number 42030410]+1 种基金additionally supported by the Startup Foundation for Introducing Talent of NUISTJiangsu Innovation Research Group[grant number JSSCTD202346]。
文摘Global warming induced by increased CO_(2) has caused marked changes in the ocean.Previous estimates of ocean salinity change in response to global warming have considerable ambiguity,largely attributable to the diverse sensitivities of surface fluxes.This study utilizes data from the Flux-Anomaly-Forced Model Intercomparison Project to investigate how ocean salinity responds to perturbations of surface fluxes.The findings indicate the emergence of a sea surface salinity(SSS)dipole pattern predominantly in the North Atlantic and Pacific fresh pools,driven by surface flux perturbations.This results in an intensification of the“salty gets saltier and fresh gets fresher”SSS pattern across the global ocean.The spatial pattern amplification(PA)of SSS under global warming is estimated to be approximately 11.5%,with surface water flux perturbations being the most significant contributor to salinity PA,accounting for 8.1% of the change after 70 years in experiments since pre-industrial control(piControl).Notably,the zonal-depth distribution of salinity in the upper ocean exhibits lighter seawater above the denser water,with bowed isopycnals in the upper 400 m.This stable stratification inhibits vertical mixing of salinity and temperature.In response to the flux perturbations,there is a strong positive feedback due to consequent freshening.It is hypothesized that under global warming,an SSS amplification of 7.2%/℃ and a mixed-layer depth amplification of 12.5%/℃ will occur in the global ocean.It suggests that the salinity effect can exert a more stable ocean to hinder the downward transfer of heat,which provides positive feedback to future global warming.
基金supported by the National Key Research and Development Program of China(Grant No.2020YFA0608904)the International Partnership Program of the Chinese Academy of Sciences(Grant Nos.060GJHZ2023079GC and 134111KYSB20160031)+1 种基金supported by the Office of Science,U.S.Department of Energy(DOE)Biological and Environmental Research as part of the Regional and Global Model Analysis program area through the Water Cycle and Climate Extremes Modeling(WACCEM)scientific focus areaoperated for DOE by Battelle Memorial Institute under contract DE-AC05-76RL01830。
文摘The global monsoon system,encompassing the Asian-Australian,African,and American monsoons,sustains two-thirds of the world’s population by regulating water resources and agriculture.Monsoon anomalies pose severe risks,including floods and droughts.Recent research associated with the implementation of the Global Monsoons Model Intercomparison Project under the umbrella of CMIP6 has advanced our understanding of its historical variability and driving mechanisms.Observational data reveal a 20th-century shift:increased rainfall pre-1950s,followed by aridification and partial recovery post-1980s,driven by both internal variability(e.g.,Atlantic Multidecadal Oscillation)and external forcings(greenhouse gases,aerosols),while ENSO drives interannual variability through ocean-atmosphere interactions.Future projections under greenhouse forcing suggest long-term monsoon intensification,though regional disparities and model uncertainties persist.Models indicate robust trends but struggle to quantify extremes,where thermodynamic effects(warming-induced moisture rise)uniformly boost heavy rainfall,while dynamical shifts(circulation changes)create spatial heterogeneity.Volcanic eruptions and proposed solar radiation modification(SRM)further complicate predictions:tropical eruptions suppress monsoons,whereas high-latitude events alter cross-equatorial flows,highlighting unresolved feedbacks.The emergent constraint approach is booming in terms of correcting future projections and reducing uncertainty with respect to the global monsoons.Critical challenges remain.Model biases and sparse 20th-century observational data hinder accurate attribution.The interplay between natural variability and anthropogenic forcings,along with nonlinear extreme precipitation risks under warming,demands deeper mechanistic insights.Additionally,SRM’s regional impacts and hemispheric monsoon interactions require systematic evaluation.Addressing these gaps necessitates enhanced observational networks,refined climate models,and interdisciplinary efforts to disentangle multiscale drivers,ultimately improving resilience strategies for monsoon-dependent regions.
文摘The 2008 Olympic Games in Beijing will provide a good opportunity to boost China’s public relations industry It seems like an impossible mission to enable a foreigner to experience China’s 5,000-year history in just a few hours,but Mark Zhou, a Chinese, and Alex Koi, a Singaporean, have done just that.In an effort to enable people to get to know China, they have launched “urban safari” activities, in which the participants in a simulated environment can enjoy all kinds of food, videotapes and a detailed explanation to get an intimate feel of China’s history, culture, arts and folk customs in just six hours.
基金supported by the Australian Research Council(Grant No.CE230100012)。
文摘The onset,cessation,and length of the rainy season are crucial for global water resources,agricultural practices,and food security.However,the response of precipitation seasonality to global warming remains uncertain.In this study,we analyze how global warming levels(GWLs)of 1.5℃ and 2℃ could affect the timing of rainfall onset(RODs),rainfall cessation(RCDs),and the overall duration of the rainy season(LRS)over global land monsoon(GLM)regions using simulations from CMIP6 under the SSP2-4.5 and SSP5-8.5 scenarios.With high model consensus,our results reveal that RODs are projected to occur later over Southern Africa,North Africa,and South America,but earlier over South Asia and Australia,in a warmer climate.The projected early RODs in Australia are more pronounced at the 2℃ GWL under SSP5-8.5.On the other hand,early RCDs are projected over South America and East Asia,while late RCDs are projected over North Africa,with high inter-model agreement.These changes are associated with a future decrease in LRS in most GLM regions.Additionally,we found that continuous warming over 1.5℃ will further reduce the length of the rainy season,especially over the South America,North Africa,and Southern Africa monsoon regions.The findings underscore the urgent need to mitigate global warming.
文摘Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].
基金Supported by the National(Key) Basic Research and Development(973) Program of China(2015CB453202 and 2016YFA0601802)National Natural Science Foundation of China(41421004,41528502,and 41375085)
文摘Considering the importance of black carbon （BC）, this study began by comparing the 20th century simulation of South Asian summer climate in IPCC CMIP3, based on the scenario of models with and without BC. Generally, the multi-model mean of the models that include BC reproduced the observed climate relatively better than those that did not. Then, the 21st century South Asian summer precipitation was projected based on the IPCC CMIP3 projection simulations. The projected precipitation in the present approach exhibited a considerable difference from the multi- model ensemble mean （MME） of IPCC AR4 projection simulations, and also from the MME of the models that ig- nore the effect of BC. In particular, the present projection exhibited a dry anomaly over the central Indian Peninsula, sandwiched between wet conditions on the southern and northern sides of Pakistan and India, rather than homogen- eous wet conditions as seen in the MME of IPCC AR4. Thus, the spatial pattern of South Asian summer rainfall in the future may be more complicated than previously thought.
基金supported by the National Key R&D Program of China(grant number:2021YFC2500400)National Natural Science Foundation of China(grant numbers:82172894,82073028,82204121)China Postdoctoral Science Foundation(grant number:2023M742617).
文摘Background Cervical cancer is the only cancer that can be eliminated worldwide.Tracking the latest burden of cervical cancer is critical toward the targets set by World Health Organization(WHO)to eliminate cervical cancer as a major public health problem.Methods All data were extracted from the Global Cancer Observatory(GLOBOCAN)2022.Age-standardized incidence rate(ASIR)and mortality rates(ASMR)of cervical cancer were compared and linked to Human Development Index(HDI)between populations.The estimated annual percentage changes(EAPCs)were used to characterize the temporal trend in ASIR/ASMR,and demographic estimates were projected up to 2050.Results Globally,an estimated 662,044 cases(ASIR:14.12/100,000)and 348,709 deaths(ASMR:7.08/100,000)from cervical cancer occurred in 2022,corresponding to the fourth cause of cancer morbidity and mortality in women worldwide.Specifically,42%of cases and 39%of deaths occurred in China(23%and 16%)and India(19%and 23%).Both ASIR and ASMR of cervical cancer decreased with HDI,and similar decreasing links were observed for both early-onset(0–39 years)and late-onset(≥40 years)cervical cancer.Both ASIR and ASMR of overall cervical cancer showed decreasing trends during 2003–2012(EAPC:0.04%and-1.03%);however,upward trends were observed for early-onset cervical cancer(EAPC:1.16%and 0.57%).If national rates in 2022 remain stable,the estimated cases and deaths from cervical cancer are projected to increase by 56.8%and 80.7%up to 2050.Moreover,the projected increase of early-onset cervical cancer is mainly observed in transitioning countries,while decreased burden is expected in transitioned countries.Conclusions Cervical cancer remains a common cause of cancer death in many countries,especially in transitioning countries.Unless scaling-up preventive interventions,human papillomavirus(HPV)vaccination and cervical cancer screening,as well as systematic cooperation within government,civil societies,and private enterprises,the global burden of cervical cancer would be expected to increase in the future.
文摘Within the framework of the 2030 Agenda and to achieve the Sustainable Development Goals(SDGs),science,technology and innovation play an even more central role.Building on this foundation,the primary objective of this paper is to explore the potential applications of blockchain in supporting the achievement of these sustainability goals.Starting from a review of the relevant literature on this topic,the main fields in which blockchain can contribute to sustainable development will be identified.The main blockchain applications will then be analyzed and categorized according to these SDGs.This research will then critically present the main blockchain-based projects that emerged in the first stage of the study and were implemented by the United Nations.The main objectives and benefits of each project will be analyzed.This is where the originality of this paper lies.To the best of the author’s knowledge,this is one of the first attempts to present a comprehensive overview of the United Nations’projects related to SDGs 1,2,5,7,9,13,and 16.This paper,which bridges the gap between innovation management and the sustainability field,will contribute to the increasingly current debate on sustainability issues and be beneficial to scholars,practitioners,and policymakers alike.
