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Organ Preservation:History,Advancements,and Perspectives
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作者 Xinmeng Liu Zhiquan Shu +3 位作者 Liming Zhang Haoyue Li Jing Yang Lei Zhang 《Engineering》 2025年第1期112-134,共23页
Recent advances in organ transplantation,regenerative medicine,and drug discovery have emphasized the critical importance of effective preservation techniques for organs.Despite these advances,current preservation tec... Recent advances in organ transplantation,regenerative medicine,and drug discovery have emphasized the critical importance of effective preservation techniques for organs.Despite these advances,current preservation techniques have significant limitations in maintaining the viability and functional efficacy of organs over the long term.As a result,there is a pressing need to develop reliable and efficient preservation strategies for organs.Currently,the clinical standard for organ preservation involves the use of static cold storage and organ machine perfusion,but these methods can only preserve organs for a couple of days or even a few hours.Notably,the development of cryobiology has yielded promising alternatives.In this review,we aim to provide a comprehensive overview of the progression of organ preservation methods,while emphasizing the limitations of traditional approaches.Moreover,we evaluate advanced preservation techniques for organs,including kidneys,livers,hearts,lungs,and intestines.Furthermore,we share a progress perspective on the future of organ preservation,with the ultimate goal of achieving viable long-term preservation to address the pressing issue of organ shortage. 展开更多
关键词 Organ preservation Organ machine perfusion Static cold storage VITRIFICATION preservation solution
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Advances in fertility preservation and pregnancy care for transplant patients
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作者 Velik Lazarov Emilia Naseva +4 位作者 Dimitrina Georgieva Miteva Latchezar P Tomov Russka Shumnalieva Milena Peruhova Tsvetelina Velikova 《World Journal of Transplantation》 2025年第3期91-100,共10页
Fertility preservation and pregnancymanagement are critical considerations for patients undergoing organtransplantation.Innovations in assisted reproductive technologies,hormonalmodulation,and personalized medicine ha... Fertility preservation and pregnancymanagement are critical considerations for patients undergoing organtransplantation.Innovations in assisted reproductive technologies,hormonalmodulation,and personalized medicine have expanded options for these patients,who face unique challenges due to immunosuppressive therapy and organ functionconcerns.This mini-review explores advancements in cryopreservationtechniques,pre-conception counseling,and multidisciplinary strategies forsafe pregnancies post-transplantation.Emphasis is placed on balancing maternalhealth,graft function,and fetal outcomes.The integration of reproductive andtransplant medicine is paving the way for improved quality of life andreproductive autonomy for this patient population. 展开更多
关键词 Fertility preservation Pregnancy management Organ transplantation CRYOpreservATION Assisted reproductive technology Immunosuppressive therapy Reproductive health
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Role of preservation conditions on enrichment and fluidity maintenance of medium to high maturity lacustrine shale oil 被引量:1
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作者 ZHAO Wenzhi LIU Wei +9 位作者 BIAN Congsheng LIU Xianyang PU Xiugang LU Jiamin LI Yongxin LI Junhui LIU Shiju GUAN Ming FU Xiuli DONG Jin 《Petroleum Exploration and Development》 2025年第1期1-16,共16页
In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons ... In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons in source rocks of lacustrine shale,yet this aspect has received little attention.This paper,based on the case analysis,explores how preservation conditions influence the enrichment of mobile hydrocarbons in shale oil.Research showns that good preservation conditions play three key roles.(1)Ensure the retention of sufficient light hydrocarbons(C_(1)–C_(13)),medium hydrocarbons(C_(14)–C_(25))and small molecular aromatics(including 1–2 benzene rings)in the formation,which enhances the fluidity and flow of shale oil;(2)Maintain a high energy field(abnormally high pressure),thus facilitating the maximum outflow of shale oil;(3)Ensure that the retained hydrocarbons have the miscible flow condition of multi-component hydrocarbons(light hydrocarbons,medium hydrocarbons,heavy hydrocarbons,and heteroatomic compounds),so that the heavy hydrocarbons(C_(25+))and heavy components(non-hydrocarbons and asphaltenes)have improved fluidity and maximum flow capacity.In conclusion,in addition to the advantages of organic matter type,abundance,thermal maturity,and reservoir space,good preservation conditions of shale layers are essential for the formation of economically viable shale oil reservoirs,which should be incorporated into the evaluation criteria of shale oil-rich areas/segments and considered a necessary factor when selecting favorable exploration targets. 展开更多
关键词 medium-to-high maturity lacustrine shale oil mobile hydrocarbon enrichment preservation conditions stratum energy field miscible hydrocarbon component retained hydrocarbon fluidity Songliao Basin Ordos Basin Junggar Basin Bohai Bay Basin
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Preparation of Biodegradable Polylactic Acid/Ethyl Cellulose/Zein Composite Film and Its Effect on the Preservation of Chilled Fresh Meat
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作者 ZHOU Ling YU Ya +8 位作者 YUAN Mengting WU Dongxu CHEN Ya LIU Yanan SU Jingjing CHEN Sihan WANG Juhua SHENG Bulei XUE Xiuheng 《食品科学》 北大核心 2025年第15期324-337,共14页
In this study,composite films consisting of polylactic acid(PLA),ethyl cellulose(EC),and zein were prepared by solution casting method,and their performance and application in chilled fresh meat preservation were inve... In this study,composite films consisting of polylactic acid(PLA),ethyl cellulose(EC),and zein were prepared by solution casting method,and their performance and application in chilled fresh meat preservation were investigated.The results showed that the three materials had satisfactory compatibility in the composite film.Addition of EC and zein effectively improved the mechanical properties,thermodynamic properties,surface hydrophilicity,oxygen permeability,and degradation properties of PLA films.When the ratio of PLA to EC was 3:7,the tensile strength and elongation at break reached maximum values of 16.6 MPa and 30.5%,respectively.Moreover,under different conditions,the composite film exhibited better degradability than the PLA film.The composite film with a 3:7 ratio of PLA to EC had the best performance,with a degradation rate of 21.75%after 84 days.Chilled fresh meat wrapped with the composite film showed significantly improved antioxidant,antibacterial,and water-holding properties. 展开更多
关键词 biodegradable film polylactic acid ethyl cellulose ZEIN chilled fresh meat preservATION
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Functional Lactiplantibacillus plantarum P10 screened from Chinese traditional pickle showing application potential in steamed bread for in-situ bio-preservation and GABA-enrichment
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作者 Mengge Ma Yajuan Zhang +4 位作者 Dongchun Zhang Yi Chen Zhixin Wang Yingmin Jia Yawei Ning 《Food Science and Human Wellness》 2025年第1期190-202,共13页
Mold spoilage and nutrition enrichment are major concerns of Chinese steamed bread,and using functional lactic acid bacteria as starter to play the role of in-situ preservation and nutritional fortification was a prom... Mold spoilage and nutrition enrichment are major concerns of Chinese steamed bread,and using functional lactic acid bacteria as starter to play the role of in-situ preservation and nutritional fortification was a promising alternative.Hence,Lactiplantibacillus plantarum P10 capable of inhibiting spoilage microorganisms and producing γ-aminobutyric acid(GABA)(380 mg/L)was screened from Chinese pickle.Metabolomics analysis showed that P10 produced key antimicrobial metabolites mainly including ten organic acids,aldehyde,alkaloid.Besides,P10 might exhibit health beneficial effects such as degrading cholesterol,lowering blood glucose and reducing uric acid due to the production of deoxycholic acid and Ile-Pro-Ile,and the degradation of purine.Finally,the promising application potential of P10 was evidenced in steamed bread with extended shelf life,excellent anti-aging effect,and 24.5-fold enrichment of GABA.Conclusively,this investigation could provide scientific basis for the application of P10 as a functional starter in steamed bread. 展开更多
关键词 Lactiplantibacillus plantarum preservATION STARTER Steamed bread Metabolomics
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Effects of organic acid-preserved cereal grains in sow diets during late gestation and lactation on the performance and faecal microbiota of sows and their offspring
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作者 Shane Maher Torres Sweeney +2 位作者 Stafford Vigors Michael McDonald John V.O’Doherty 《Journal of Animal Science and Biotechnology》 2025年第4期1561-1576,共16页
Background Organic acids(OA)and maternal nutritional strategies have been demonstrated to promote piglet health and development.The objective of this study was to investigate the effects of incorporating OA-preserved ... Background Organic acids(OA)and maternal nutritional strategies have been demonstrated to promote piglet health and development.The objective of this study was to investigate the effects of incorporating OA-preserved cereal grains into sow diets during late gestation and lactation,aiming to reduce the metabolic demands of lactation while optimising offspring development and growth until slaughter.The experiment compared OA-preserved wheat and barley to conventionally dried grains,focusing on sow and offspring performance,as well as their faecal microbiota during lactation.Forty sows were blocked based on parity,body weight and back fat thickness on d 100 of gestation and assigned to one of two diets:a dried grain lactation diet and a preserved grain lactation diet.Sow faecal samples were collected at farrowing for the coefficient of apparent total tract digestibility(CATTD)of nutrients and microbial analysis.Offspring faecal samples were collected on d 10 postpartum and at weaning(d 26 postpartum)for microbial analysis.Results Sow body weight,back fat changes,gestation and lactation length,total piglets born,wean-to-oestrus interval,and lactation efficiency were unaffected by sow diet(P>0.05).However,sows offered the preserved grain diet exhibited improved CATTD of dry matter,nitrogen,gross energy,and neutral detergent fibre(P<0.05).While no maternal effect was observed on offspring growth during lactation(P>0.05),pigs from sows offered the preserved grain diet showed improved growth and feed efficiency from weaning until slaughter(d 168)compared to those from sows offered the dried grain diet(P<0.05).The preserved grain diet also reduced the abundance of Proteobacteria in sow faeces at farrowing and in their offspring on d 10 postpartum,and improved piglet faecal scores throughout lactation(P=0.05).At weaning,piglets from sows offered the preserved grain diet exhibited an increased abundance of Lactobacillus and reduced abundance of Alistipes in their faeces(P<0.05).Conclusion OA-preserved grains enhanced the CATTD of nutrients in sows,promoted healthier piglet faecal scores during lactation,and improved offspring growth performance post-weaning,potentially linked to beneficial changes observed in the faecal microbiota of sows and their offspring during lactation. 展开更多
关键词 Cereal preservation Lactation feeding MICROBIOTA Nutrient digestibility OFFSPRING Organic acids SOWS
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Gabon:Preserving forests for sustainable development
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作者 王琳琳 《疯狂英语(新悦读)》 2025年第7期53-54,79,共3页
Gabon,located on the west coast of Central Africa,is one of the most forested countries.This small but richly biodiverse country is covered by rainforests,which make up approximately 85%of its land area.These forests ... Gabon,located on the west coast of Central Africa,is one of the most forested countries.This small but richly biodiverse country is covered by rainforests,which make up approximately 85%of its land area.These forests are home to a wide variety of wildlife,including elephants and numerous bird species,making Gabon a crucial area for conservation efforts. 展开更多
关键词 BIODIVERSITY GABON sustainable development forest preservation RAINFORESTS wildlife conservation
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Impact of Composite Preservation System on the Vulcanization Performance of Natural Rubber Latex
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作者 Li-Guang Zhao Yi-Qun Liu +7 位作者 Min-Min Chen Jian-Wei Li Tuo Dai Shao-Xiang Ye Wei-Qiang Liu Tao Zhao Hong-Xing Gui Zhen-Xiang Xin 《Chinese Journal of Polymer Science》 2025年第9期1638-1650,I0012,共14页
The thioacetamide derivative(TD)-composite preservation system(TDCPS)exhibits superior preservation effects on natural rubber latex(NRL)and significantly enhances its vulcanization efficiency and mechanical properties... The thioacetamide derivative(TD)-composite preservation system(TDCPS)exhibits superior preservation effects on natural rubber latex(NRL)and significantly enhances its vulcanization efficiency and mechanical properties.This study primarily investigated the principal chemical groups and mechanism of action of TDCPS in promoting NRL vulcanization through a comparative analysis.The results indicated that the key functional groups(thioamide and pyridine)in TDCPS synergistically accelerated crosslinking,reducing the vulcanization time by 41.18%compared to the high-ammonia(HA)preservation system.At an optimal TDCPS dosage of 5 mmol·L^(−1),vulcanized films achieved a tensile strength of 34.18 MPa,with a sulfur content of 1.5 phr further improving the strength by 42.26%.TD outperformed the conventional accelerators 2-imidazolidinethione(ETU)and 3-hydroxypyridine(3-Hp)in promoting the crosslinking density and mechanical performance while eliminating ammonia-related environmental risks.This eco-friendly system demonstrates the industrial potential for sustainable rubber production. 展开更多
关键词 Natural rubber latex preservation system Thioacetamide derivative VULCANIZATION Mechanical properties
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Revitalizing upper blepharoplasty:Preserving volume
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作者 Rana Farsakoury Abdulqadir J Nashwan 《World Journal of Clinical Cases》 2025年第15期66-68,共3页
Blepharoplasty is a frequently performed aesthetic surgery today aimed at enhancing eyelid appearance and correcting age-related changes.The traditional method of subtraction blepharoplasty,which involved removing fat... Blepharoplasty is a frequently performed aesthetic surgery today aimed at enhancing eyelid appearance and correcting age-related changes.The traditional method of subtraction blepharoplasty,which involved removing fat and excess skin,is now considered outdated.This letter explores Gorgy et al's commentary on Miotti et al's study,highlighting a shift in upper eyelid blepharoplasty towards a more conservative,volume-preserving approach.The study systematically reviewed 10 publications,including three retrospective studies,five comparative studies,and two clinical trials.It emphasizes the trend towards preserving the patient's natural anatomy and focusing on enhancement rather than alteration.However,the study's limitations,such as the lack of long-term comparative re-search,a relatively small sample size,and a single-center design,indicate that further research with extended follow-up is necessary to validate the safety and effectiveness of these techniques.The focus is increasingly on preserving and augmenting volume in upper blepharoplasty rather than removing tissue. 展开更多
关键词 Upper lid blepharoplasty Volume preservation Fat pad Aesthetic longevity BLEPHAROPLASTY
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Predictive model for sphincter preservation in lower rectal cancer
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作者 Yajnadatta Sarangi Ashok Kumar 《World Journal of Clinical Oncology》 2025年第8期201-219,共19页
BACKGROUND Low rectal cancer poses a significant surgical challenge because of its close proximity to the anal sphincter,often requiring radical resection with permanent colostomy to achieve oncological safety.Revisit... BACKGROUND Low rectal cancer poses a significant surgical challenge because of its close proximity to the anal sphincter,often requiring radical resection with permanent colostomy to achieve oncological safety.Revisited rectal anatomy,advances in surgical techniques and neoadjuvant therapies have enabled the possibility of sphincter-preserving procedures,however,it is uniformly not applicable.Selecting appropriate candidates for sphincter preservation is crucial,as an illadvised approach may compromise oncological outcome or lead to poor functional outcomes.Currently there is no consensus-which clinical,anatomical,or molecular factors most accurately predict the feasibility of sphincter-preserving surgery(SPS)in this subset of patients.By identifying these predictors,the study seeks to support improved patient selection,enhance surgical planning,and ultimately contribute to better functional and oncological outcomes in patients with low rectal cancer.AIM To identify predictive factors that determine the feasibility of SPS in patients with low rectal cancer.METHODS A comprehensive literature search was conducted using PubMed/MEDLINE databases.The search focused on various factors influencing the feasibility of SPS in low rectal cancer.These included patient-related factors,anatomical considerations,findings from different imaging modalities,advancements in diagnostic tools and techniques,and the role of neoadjuvant chemoradiotherapy.The relevance of each factor in predicting the potential for sphincter preservation was critically analyzed and presented based on the current evidence RESULTS Multiple studies have identified a range of predictive factors influencing the feasibility of SPS in low rectal cancer.Patient-related factors include age,sex,preoperative continence status,comorbidities,and body mass index.Anatomical considerations,such as tumor distance from the anal verge,involvement of the external anal sphincter,and levator ani muscles,also play a critical role.Additionally,a favourable response to neoadjuvant chemoradiotherapy has been associated with improved suitability for sphincter preservation.Several biomarkers,such as inflammatory markers like interleukins and C-reactive protein,as well as tumor markers like carcinoembryonic antigen,are important.Molecular markers,including BRAF and KRAS mutations and microsatellite instability status,have been linked to prognosis and may further guide decision-making regarding sphincter-preserving approaches.Artificial intelligence(AI)can further add in to select an ideal patient for sphincter preservation.CONCLUSION SPS is feasible in low rectal cancer and depends on patient factors,tumor anatomy and biology,preoperative treatment response,and biomarkers.In addition,tools and technology including AI can further help in selecting an ideal patient for long term optimal outcome. 展开更多
关键词 Low rectal cancer SURGERY Sphincter preservation Predictive model FACTORS
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Self-Assembled Hollow Microporous Organic Polymers Embedded in Polymer Fibers for Advanced Food Preservation
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作者 Jingli Li Xianting Fu +4 位作者 Yuheng Wen Hailang Xu Qian Liao Deng-Guang Yu Wenliang Song 《Journal of Polymer Materials》 2025年第2期435-448,共14页
Porous organic polymers are remarkably versatile materials with porous and carefully designed structures.They complement traditional preservation methods by overcoming their limitations and significantly extending the... Porous organic polymers are remarkably versatile materials with porous and carefully designed structures.They complement traditional preservation methods by overcoming their limitations and significantly extending the shelf life of preserved products.Notably,porous hollow nanospheres(PHNs),with their unique hollow structures capable of adsorbing and releasing organic molecules,have garnered considerable attention in food preservation.However,most PHNs are challenging to synthesize in one step,and PHNs are usually in powder form,which makes it challenging to apply them directly.In this study,we successfully synthesized PHNs in one step using the Friedel–Crafts reaction.The PHNs,adsorbed with hexanal molecules,were then embedded in polymer fibers to create composites via electrospinning.The preservation effect of the composite nanofiber membranes was investigated by determining the changes in appearance,weight,peel hardness,and pulp sugar content of three fruits,namely strawberries,bananas,and kumquats,after several days of storage.In comparison to pure poly(ε-caprolactone)fiber membranes,PHNs containing hexanal molecules slowed down the oxidative deterioration process and enhanced the quality and flavor of preserved fruits.This research presents innovative approaches for using porous organic polymers in food preservation and serves as a valuable reference for the development of future food packaging materials. 展开更多
关键词 Porous hollow nanospheres HEXANAL food preservation ELECTROSPINNING
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Plant natural products as effective options for inhibiting foodborne pathogens: a comprehensive review of their activities, mechanisms, and applications in food preservation
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作者 Menglong Liu Haiyan Ding +3 位作者 Yu Cao Lijing Liu Qiaoli Xue Yongjin Hu 《Food Science and Human Wellness》 2025年第9期3388-3413,共26页
In order to ensure food safety,controlling foodborne pathogen contamination is of utmost importance.Growing apprehensions regarding the safety of synthetic antimicrobials,due to their adverse health effects,have promp... In order to ensure food safety,controlling foodborne pathogen contamination is of utmost importance.Growing apprehensions regarding the safety of synthetic antimicrobials,due to their adverse health effects,have prompted a search for alternative options.Plant natural products(PNPs)with antimicrobial activity are being explored as a viable alternative.Among the various antimicrobial natural products studied,plant essential oils,plant flavonoids,plant polyphenols,plant polysaccharides,and plant antimicrobial peptides have been identified as potential candidates.PNPs demonstrate a diverse array of antimicrobial mechanisms,encompassing cell wall and membrane damage,interference with genetic replication,disruption of energy metabolism,and induction of oxidative stress at the single-cell level,as well as inhibition of biofilm formation and quorum sensing at the population level.Certain PNPs have been harnessed as natural antimicrobial agents for the food preservation.The utilization of encapsulation technology proves to be an effective strategy in protecting PNPs,thereby ensuring good antimicrobial efficacy,enhanced dispersibility,and controlled release within food products.The utilization of nanoemulsions,nanoliposomes,edible packaging,electrospun nanofibers,and microcapsules formed by encapsulation has enriched the ways in which PNPs can be applied in food preservation.Although PNPs have great potential in food preservation,their widespread application in the food industry is currently constrained by factors such as production costs,safety concerns,and legal considerations.Chemical synthesis and biosynthesis pathways offer viable strategies for reducing the cost of producing PNPs,and ongoing efforts to assess safety and improve regulatory frameworks are likely to facilitate the broader adoption of PNPs in food preservation practices.This article provides an overview of the main types of PNPs with antimicrobial activity and their properties,focusing on their mechanisms of action.Additionally,it summarizes the use of PNPs in food preservation and discusses the characteristics and applications of different encapsulation technologies.Lastly,the paper briefly analyzes current limitations and proposes potential future trends for this field. 展开更多
关键词 Plant natural products Foodborne pathogens Antimicrobial activity Antimicrobial mechanism Food preservation ENCAPSULATION
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Preserving the Past China’s approach and experience in heritage conservation is worth emulating by other countries
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《ChinAfrica》 2025年第1期33-35,共3页
n recent years,China has placed increasing emphasis on the protection of cultural heritage.In July 2024,Beijing’s Central Axis was o!cially inscribed on the World Heritage List,and on 4 December 2024,the Spring Festi... n recent years,China has placed increasing emphasis on the protection of cultural heritage.In July 2024,Beijing’s Central Axis was o!cially inscribed on the World Heritage List,and on 4 December 2024,the Spring Festival was added to the UNESCO Intangible Cultural Heritage list.Public awareness of the importance of preserving historical sites and promoting the inheritance and celebration of Chinese civilisation has also grown significantly. 展开更多
关键词 UNESCO preservING HERITAGE
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Risk factors influencing sphincter preservation in laparoscopic radical rectal cancer surgery
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作者 Jia-Rui Liu Jin Zhang Xiang-Long Duan 《World Journal of Gastrointestinal Surgery》 2025年第3期240-248,共9页
BACKGROUND The surgical management of rectal cancer is continuously advancing,with a current emphasis on minimising the need for a permanent stoma.Understanding the risk factors influencing sphincter preservation is c... BACKGROUND The surgical management of rectal cancer is continuously advancing,with a current emphasis on minimising the need for a permanent stoma.Understanding the risk factors influencing sphincter preservation is crucial for guiding clinical decision-making and optimising preoperative patient evaluation.AIM To examine the risk factors influencing sphincter preservation in laparoscopic radical rectal cancer surgery.METHODS A retrospective analysis of the demographics,preoperative and intraoperative data,and pathological findings of 179 patients with rectal cancer who underwent laparoscopic radical rectal cancer surgery at our hospital between January 2022 and December 2023 was conducted.These clinical data were compared between two groups:Patients with sphincter preservation and those without,categorised as the sphincter-preserved and sphincter-unpreserved groups,respectively.RESULTS Of the 179 patients analysed,150 were in the sphincter-preserved group and 29 were in the sphincter-unpreserved group.Tumour height was significantly greater in the sphincter-preserved group compared to the sphincter-unpreserved group.Conversely,elevated levels of carcinoembryonic antigen,carbohydrate antigen 19-9,and plasma D-dimer were significantly higher in the sphincter-unpreserved group.Significant differences were also observed between the two groups in terms of place of residence,presence of colonic polyps,neoadjuvant chemotherapy,preoperative radiotherapy,mucinous adenocarcinoma,nerve invasion,and tumour height.No significant differences were observed for other parameters.Logistic regression analysis identified colonic polyps,mucinous adenocarcinoma,nerve invasion,and tumour height as independent risk factors for sphincter preser-vation.CONCLUSION Several risk factors influencing sphincter preservation in laparoscopic radical rectal cancer surgery were identified.These factors could be valuable tools for guiding clinical decision-making and optimising preoperative patient evaluations. 展开更多
关键词 Rectal cancer Laparoscopic surgery Sphincter preservation Risk factors Preoperative evaluation
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Indications and techniques for minimally invasive spleen-preserving distal pancreatectomy
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作者 David Gutierrez Blanco Marcio Apodaca-Rueda +4 位作者 Carlos T Maeda Camila G C Y Carvalho Erin Baker John B Martinie Raphael L C Araujo 《World Journal of Gastrointestinal Surgery》 2025年第10期81-89,共9页
Spleen-preserving distal pancreatectomy(SPDP)has gained increasing attention as a safe and effective alternative to distal pancreatectomy with splenectomy,particularly for benign and low-grade malignant lesions of the... Spleen-preserving distal pancreatectomy(SPDP)has gained increasing attention as a safe and effective alternative to distal pancreatectomy with splenectomy,particularly for benign and low-grade malignant lesions of the pancreatic body and tail.This narrative review evaluates the current evidence,technical considerations,and disease-specific indications for SPDP.Literature was reviewed using up to date scientific evidence and most recent national and international guidelines.Studies addressing SPDP outcomes,splenectomy complications,and disease-specific oncologic principles were included.Spleen preservation has been associated with reduced rates of postoperative infections,thromboembolic events,and longterm immunologic compromise,without compromising oncologic outcomes in selected patients.Indications favoring SPDP include pancreatic neuroendocrine tumors,intraductal papillary mucinous neoplasms,and solid pseudopapillary neoplasms.Although current guidelines generally recommend splenectomy for pancreatic ductal adenocarcinoma,emerging data suggest that spleen preservation may be feasible in highly selected cases.Technical approaches—primarily the Kimura and Warshaw techniques—enable safe dissection and splenic vessel management,particularly with the support of minimally invasive platforms.In conclusion,SPDP should be considered in appropriately selected patients to reduce morbidity while preserving long-term immune function.Future randomized studies are warranted to define oncologic safety and refine indications across tumor types. 展开更多
关键词 PANCREAS Distal pancreatectomy Spleen preservation Minimally invasive surgery
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MMH-FE:AMulti-Precision and Multi-Sourced Heterogeneous Privacy-Preserving Neural Network Training Based on Functional Encryption
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作者 Hao Li Kuan Shao +2 位作者 Xin Wang Mufeng Wang Zhenyong Zhang 《Computers, Materials & Continua》 2025年第3期5387-5405,共19页
Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.P... Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.Previous schemes have achieved secure outsourced computing,but they suffer from low computational accuracy,difficult-to-handle heterogeneous distribution of data from multiple sources,and high computational cost,which result in extremely poor user experience and expensive cloud computing costs.To address the above problems,we propose amulti-precision,multi-sourced,andmulti-key outsourcing neural network training scheme.Firstly,we design a multi-precision functional encryption computation based on Euclidean division.Second,we design the outsourcing model training algorithm based on a multi-precision functional encryption with multi-sourced heterogeneity.Finally,we conduct experiments on three datasets.The results indicate that our framework achieves an accuracy improvement of 6%to 30%.Additionally,it offers a memory space optimization of 1.0×2^(24) times compared to the previous best approach. 展开更多
关键词 Functional encryption multi-sourced heterogeneous data privacy preservation neural networks
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The Role of Digital Learning in Preserving and Promoting Cambodian Culture in Higher Education
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作者 CHHUON Chanthan ORK Sovannaroth KOL Senghak 《云南开放大学学报》 2025年第3期15-21,共7页
This research examines the use of digital learning to preserve and promote Cambodian culture in universities.As benefits and challenges of globalization and modernization abound,digital learning along with the quicken... This research examines the use of digital learning to preserve and promote Cambodian culture in universities.As benefits and challenges of globalization and modernization abound,digital learning along with the quickening pace of social advancement provides new opportunities for students and faculty to sustain cultural heritage,enhance student engagement,and create inclusive education.This study explores two questions:1)how does foreign culture appear in Cambodian English textbooks and 2)how might digital learning be used to co-decolonize in a way creates gender and cultural inclusivity?The study adopts an analysis-by-synthesis method and dissects and synthesizes the various components—technology infrastructure,faculty preparedness,student engagement,and cultural content—how they interacted with one another,and how they interacted with each representative group of stakeholders.The results indicate that digital tools provide an opportunity for both higher cultural awareness and accurate representation,and gender equity.Challenges exist in accessibility to the technology infrastructure and the authentic cultural content in the digital space.The study concludes with a discussion of how to scale faculty professional development,expand the curriculum,and collaborate regionally in interoperable scaffolding in order preserve Cambodia’s cultural identity in the quickly evolving landscape of education. 展开更多
关键词 Higher Education Cultural preservation Digital Learning Cambodian Culture and Regional Cooperation
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Design and Application of a New Distributed Dynamic Spatio-Temporal Privacy Preserving Mechanisms
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作者 Jiacheng Xiong Xingshu Chen +1 位作者 Xiao Lan Liangguo Chen 《Computers, Materials & Continua》 2025年第8期2273-2303,共31页
In the era of big data,the growing number of real-time data streams often contains a lot of sensitive privacy information.Releasing or sharing this data directly without processing will lead to serious privacy informa... In the era of big data,the growing number of real-time data streams often contains a lot of sensitive privacy information.Releasing or sharing this data directly without processing will lead to serious privacy information leakage.This poses a great challenge to conventional privacy protection mechanisms(CPPM).The existing data partitioning methods ignore the number of data replications and information exchanges,resulting in complex distance calculations and inefficient indexing for high-dimensional data.Therefore,CPPM often fails to meet the stringent requirements of efficiency and reliability,especially in dynamic spatiotemporal environments.Addressing this concern,we proposed the Principal Component Enhanced Vantage-point tree(PEV-Tree),which is an enhanced data structure based on the idea of dimension reduction,and constructed a Distributed Spatio-Temporal Privacy Preservation Mechanism(DST-PPM)on it.In this work,principal component analysis and the vantage tree are used to establish the PEV-Tree.In addition,we designed three distributed anonymization algorithms for data streams.These algorithms are named CK-AA,CL-DA,and CT-CA,fulfill the anonymization rules of K-Anonymity,L-Diversity,and T-Closeness,respectively,which have different computational complexities and reliabilities.The higher the complexity,the lower the risk of privacy leakage.DST-PPM can reduce the dimension of high-dimensional information while preserving data characteristics and dividing the data space into vantage points based on distance.It effectively enhances the data processing workflow and increases algorithmefficiency.To verify the validity of the method in this paper,we conducted empirical tests of CK-AA,CL-DA,and CT-CA on conventional datasets and the PEV-Tree,respectively.Based on the big data background of the Internet of Vehicles,we conducted experiments using artificial simulated on-board network data.The results demonstrated that the operational efficiency of the CK-AA,CL-DA,and CT-CA is enhanced by 15.12%,24.55%,and 52.74%,respectively,when deployed on the PEV-Tree.Simultaneously,during homogeneity attacks,the probabilities of information leakage were reduced by 2.31%,1.76%,and 0.19%,respectively.Furthermore,these algorithms showcased superior utility(scalability)when executed across PEV-Trees of varying scales in comparison to their performance on conventional data structures.It indicates that DST-PPM offers marked advantages over CPPM in terms of efficiency,reliability,and scalability. 展开更多
关键词 Privacy preserving distributed anonymization algorithm VP-Tree data stream internet of vehicles
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Exhumation and Preservation of the Yangchuling Porphyry W-Mo Deposit in the Jiangnan Tungsten Ore Belt,South China:Insights from(U-Th)/He and Fission Track Dating
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作者 Yue Sun Ying Wang +4 位作者 Jianzhang Pang Samuel C.Boone Minting Wu Chongjian Shao Wei Liu 《Journal of Earth Science》 2025年第1期46-56,共11页
The Yangchuling porphyry W-Mo deposit(YPWD),located in the Jiangnan porphyryskarn tungsten ore belt,is one of the most important and large-scale porphyry W-Mo deposits in South China.While previous zircon U-Pb and mol... The Yangchuling porphyry W-Mo deposit(YPWD),located in the Jiangnan porphyryskarn tungsten ore belt,is one of the most important and large-scale porphyry W-Mo deposits in South China.While previous zircon U-Pb and molybdenite Re-Os data suggest that Yangchuling WMo ore bodies formed almost simultaneously with granodiorite and monzogranitic porphyry at~150–144 Ma,their post emplacement history remains poorly understood,making their preservation status at depth uncertain.In this paper,new zircon and apatite(U-Th)/He and apatite fission track(ZHe,AHe and AFT,respectively)data of one hornfels and five intrusive rocks from a 1000-meter borehole are presented.These,together with new inverse thermal history models and previous geochronological data,help elucidate the post-diagenetic exhumation history and preservation status of the Yangchuling porphyry W-Mo deposit.In general,ZHe and AHe ages decrease gradually from the near surface downwards and have relatively little intra-sample variation,ranging from 133 to 73Ma and 67 to 25 Ma,respectively.All four granodiorites yield similar AFT ages that range from 63 to 55 Ma with mean track lengths varying from 12.2±0.7 to 12.6±0.5μm.Thermal history modelling indicates that the Yangchuling ore district experienced slow,monotonic cooling since the Cretaceous.Age-depth relationships are interpreted as recording~3.7±0.8 km of Cretaceous-recent exhumation in response to regional extension throughout South China thought to have been driven by subduction retreat of the Paleo-Pacific Plate.Comparison of estimated net exhumation and previous metallogenic depth of~4–5 km suggests that W-Mo ore bodies could still exist at depths of up to~1.3±0.8 km relative to Earth surface in the YPWD region.Preservation of the YPWD is attributed to the limited amount of regional denudation during the Late Cretaceous and Cenozoic. 展开更多
关键词 (U-Th)/He fission track ore preservation thermochronology Yangchuling porphyry W-Mo deposit
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An Evaluation on Physical Characteristics of Konjac Polysaccharides-Based Film Coating and Its Application for Strawberries Preservation
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作者 Desy Nurliasari Awaly Ilham Dewantoro +7 位作者 Muhammad Adly Rahandi Lubis Roni Kastaman Mohamad Djali Efri Mardawati Devi Maulida Rahmah Siti Nurhasanah Akbar Hanif Dawam Abdullah Lukmanul Hakim Zaini 《Journal of Renewable Materials》 2025年第1期181-197,共17页
Konjac is an ideal candidate for edible coatings on fruits due to its hydrophilic properties,film-forming ability,barrier properties,safety,and biodegradability.Meanwhile,the high market demand for strawberries necessi... Konjac is an ideal candidate for edible coatings on fruits due to its hydrophilic properties,film-forming ability,barrier properties,safety,and biodegradability.Meanwhile,the high market demand for strawberries necessitates post-harvest treatment to extend their shelf life and preserve their quality,as strawberries are known for their fragile skin and soft texture.To fully utilize konjac and develop high-quality coatingfilms,native konjacflour(NKF)and konjac glucomannan(KGM)were extracted from its corm and used as a coatingfilm for strawberries in the present study.Therefore,this study aimed to compare the physical properties of thefilm coatings between NKF and KGM,and evaluate their effects on strawberries preservation over 7 days of storage.A multistage extrac-tion process was employed to isolate NKF and KGM,after which the glucomannan content was measured.NKF yield was 31.81%,exceeding KGM yield of 26.42%,and the glucomannan content obtained of NKF(25.93%)was higher than KGM(21.41%).Nuclear magnetic resonance spectroscopy confirmed that both NKF and KGM con-tain glucomannan in their structure.Furthermore,both NKF and KGM were combined with carboxymethyl cel-lulose(CMC)and glycerol to produce eight thin-layerfilms to assess their physical and mechanical properties.Compared to the KGM variant,the NKF variant generally exhibited higher moisture content,water vapor trans-mission rate,and tensile strength.However,NKF was less effective than KGM in extending strawberry storage life,leading to faster color changes and greater weight loss,despite maintaining similar hardness values.Nonetheless,konjac-based coatings were generally effective at maintaining the freshness and quality of strawberries compared to uncoated samples.Konjac shows promise as an edible coating,improving fresh produce shelf life and appeal,aligning with consumer preferences for natural and sustainable products. 展开更多
关键词 Amorphophalus oncophyllus coating performances ediblefilm strawberry preservation
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