Objective To evaluate the clinical efficacy of Traditional Chinese Medicine(TCM)hot-pack therapy in treating postoperative gastrointestinal dysfunction in patients undergoing surgery for gastrointestinal malignancies....Objective To evaluate the clinical efficacy of Traditional Chinese Medicine(TCM)hot-pack therapy in treating postoperative gastrointestinal dysfunction in patients undergoing surgery for gastrointestinal malignancies.Method 60 postoperative patients with gastrointestinal malignancies were randomized into a treatment group(n=30)and a control group(n=30).Both groups received standard postoperative supportive care,including oral mosapride citrate(5 mg,three times daily,starting 6 h post-op,for 3 days).The treatment group additionally received external abdominal application of a TCM hot-pack twice daily(20-30 min each)for 3 days.Primary endpoints were time to first flatus,first defecation,and first oral intake.Secondary endpoints included numeric scores for abdominal pain and distension at 24 h and 72 h post-op,and overall clinical efficacy.Result Compared with controls,the treatment group showed significantly faster recovery:time to first flatus(50.3±7.8 h vs.62.5±9.4 h),first defecation(72.1±11.3 h vs.85.2±13.6 h),and first oral intake(48.0±9.5 h vs.62.5±12.4 h)(all P<0.01).At 24 h and 72 h,the treatment group reported lower abdominal pain and distension scores(24 h pain 5.1±1.3 vs.6.0±1.4,distension 2.3±0.5 vs.2.8±0.6;72 h pain 3.9±0.8 vs.4.7±0.9,distension 1.9±0.5 vs.2.3±0.6;P<0.05 to P<0.01).Total effective rate was higher in the treatment group(96.7%vs.90.0%,χ^(2)=6.96,P=0.031).Conclusion TCM hot-pack therapy combined with routine care significantly accelerates recovery of gastrointestinal function,shortens duration of postoperative dysfunction,and alleviates abdominal pain and distension in patients after gastrointestinal malignancy surgery,demonstrating notable clinical benefit.展开更多
BACKGROUND Explore the risk factors of gastrointestinal dysfunction after gastrointestinal tumor surgery and to provide evidence for the prevention and intervention of gastrointestinal dysfunction in patients with gas...BACKGROUND Explore the risk factors of gastrointestinal dysfunction after gastrointestinal tumor surgery and to provide evidence for the prevention and intervention of gastrointestinal dysfunction in patients with gastrointestinal tumor surgery.AIM To investigate the potential risk factors for gastrointestinal dysfunction following gastrointestinal tumor surgery and to present information supporting the prevention and management of gastrointestinal dysfunction in surgery patients.METHODS Systematically searched the relevant literature from PubMed,Web of Science,Cochrane Library,Embase,CNKI,China Biomedical Database,Wanfang Database,and Weipu Chinese Journal Database self-established until October 1,2022.Review Manager 5.3 software was used for meta-analysis after two researchers independently screened literature,extracted data,and evaluated the risk of bias in the included studies.RESULTS A total of 23 pieces of literature were included,the quality of which was medium or above,and the total sample size was 43878.The results of meta-analysis showed that the patients were male(OR=1.58,95%CI:1.25-2.01,P=0.002)and≥60 years old(OR=2.60,95%CI:1.76-2.87,P<0.001),physical index≥25.3 kg/m2(OR=1.6,95%CI:1.00-1.12,P=0.040),smoking history(OR=1.89,95%CI:1.31-2.73,P<0.001),chronic obstructive pulmonary disease(OR=1.49,95%CI:1.22-1.83,P<0.001),enterostomy(OR=1.47,95%CI:1.26-1.70,P<0.001),history of abdominal surgery(OR=2.90,95%CI:1.67-5.03,P<0.001),surgical site(OR=1.2,95%CI:1.40-2.62,P<0.001),operation method(OR=1.68,95%CI:1.08-2.62,P=0.020),operation duration(OR=2.65,95%CI:1.92-3.67,P<0.001),abdominal adhesion grade(OR=2.52,95%CI:1.90-3.56,P<0.001),postoperative opioid history(OR=5.35,95%CI:3.29-8.71,P<0.001),tumor TNM staging(OR=2.58,95%CI:1.84-3.62,P<0.001),postoperative blood transfusion(OR=2.92,95%CI:0.88-9.73,P=0.010)is a risk factor for postoperative gastrointestinal dysfunction in patients with gastrointestinal tumors.CONCLUSION There are many factors affecting gastrointestinal dysfunction in gastrointestinal patients after surgery.Clinical staff should identify relevant risk factors early and implement targeted intervention measures on the basis of personalized assessment to improve the clinical prognosis of patients.展开更多
基金2024 Technological Innovation Project of Shapingba District,Chongqing(2024174)。
文摘Objective To evaluate the clinical efficacy of Traditional Chinese Medicine(TCM)hot-pack therapy in treating postoperative gastrointestinal dysfunction in patients undergoing surgery for gastrointestinal malignancies.Method 60 postoperative patients with gastrointestinal malignancies were randomized into a treatment group(n=30)and a control group(n=30).Both groups received standard postoperative supportive care,including oral mosapride citrate(5 mg,three times daily,starting 6 h post-op,for 3 days).The treatment group additionally received external abdominal application of a TCM hot-pack twice daily(20-30 min each)for 3 days.Primary endpoints were time to first flatus,first defecation,and first oral intake.Secondary endpoints included numeric scores for abdominal pain and distension at 24 h and 72 h post-op,and overall clinical efficacy.Result Compared with controls,the treatment group showed significantly faster recovery:time to first flatus(50.3±7.8 h vs.62.5±9.4 h),first defecation(72.1±11.3 h vs.85.2±13.6 h),and first oral intake(48.0±9.5 h vs.62.5±12.4 h)(all P<0.01).At 24 h and 72 h,the treatment group reported lower abdominal pain and distension scores(24 h pain 5.1±1.3 vs.6.0±1.4,distension 2.3±0.5 vs.2.8±0.6;72 h pain 3.9±0.8 vs.4.7±0.9,distension 1.9±0.5 vs.2.3±0.6;P<0.05 to P<0.01).Total effective rate was higher in the treatment group(96.7%vs.90.0%,χ^(2)=6.96,P=0.031).Conclusion TCM hot-pack therapy combined with routine care significantly accelerates recovery of gastrointestinal function,shortens duration of postoperative dysfunction,and alleviates abdominal pain and distension in patients after gastrointestinal malignancy surgery,demonstrating notable clinical benefit.
文摘BACKGROUND Explore the risk factors of gastrointestinal dysfunction after gastrointestinal tumor surgery and to provide evidence for the prevention and intervention of gastrointestinal dysfunction in patients with gastrointestinal tumor surgery.AIM To investigate the potential risk factors for gastrointestinal dysfunction following gastrointestinal tumor surgery and to present information supporting the prevention and management of gastrointestinal dysfunction in surgery patients.METHODS Systematically searched the relevant literature from PubMed,Web of Science,Cochrane Library,Embase,CNKI,China Biomedical Database,Wanfang Database,and Weipu Chinese Journal Database self-established until October 1,2022.Review Manager 5.3 software was used for meta-analysis after two researchers independently screened literature,extracted data,and evaluated the risk of bias in the included studies.RESULTS A total of 23 pieces of literature were included,the quality of which was medium or above,and the total sample size was 43878.The results of meta-analysis showed that the patients were male(OR=1.58,95%CI:1.25-2.01,P=0.002)and≥60 years old(OR=2.60,95%CI:1.76-2.87,P<0.001),physical index≥25.3 kg/m2(OR=1.6,95%CI:1.00-1.12,P=0.040),smoking history(OR=1.89,95%CI:1.31-2.73,P<0.001),chronic obstructive pulmonary disease(OR=1.49,95%CI:1.22-1.83,P<0.001),enterostomy(OR=1.47,95%CI:1.26-1.70,P<0.001),history of abdominal surgery(OR=2.90,95%CI:1.67-5.03,P<0.001),surgical site(OR=1.2,95%CI:1.40-2.62,P<0.001),operation method(OR=1.68,95%CI:1.08-2.62,P=0.020),operation duration(OR=2.65,95%CI:1.92-3.67,P<0.001),abdominal adhesion grade(OR=2.52,95%CI:1.90-3.56,P<0.001),postoperative opioid history(OR=5.35,95%CI:3.29-8.71,P<0.001),tumor TNM staging(OR=2.58,95%CI:1.84-3.62,P<0.001),postoperative blood transfusion(OR=2.92,95%CI:0.88-9.73,P=0.010)is a risk factor for postoperative gastrointestinal dysfunction in patients with gastrointestinal tumors.CONCLUSION There are many factors affecting gastrointestinal dysfunction in gastrointestinal patients after surgery.Clinical staff should identify relevant risk factors early and implement targeted intervention measures on the basis of personalized assessment to improve the clinical prognosis of patients.
