Summary:Choosing proper perfusates as contrast agents is an important aspect for postmortem magnetic resonance angiography(PMMRA).However,in this emerging field,the number of suitable kinds of liquid is still very lim...Summary:Choosing proper perfusates as contrast agents is an important aspect for postmortem magnetic resonance angiography(PMMRA).However,in this emerging field,the number of suitable kinds of liquid is still very limited.The objective of this research is to compare MR images of oleic acid(OA)with paraffin oil(PO)in vitro and in ex situ animal hearts,in order to evaluate the feasibility to use OA as a novel contrast agent for PMMRA.In vitro,OA,PO and water(control)were introduced into three tubes separately and T,weighted-spin echo(Tw SE)and T2w-SE images were acquired on a 1.5T MR scanner.In the second experiment,0A and PO were injected into left coronary artery(LCA)and left ventricle(LV)of ex situ bovine hearts and their Tw-SE,Tzw-SE,Tw-multipoint Dixon(Tjw-mDixon)and 3DT2w-mDixon images were acquired.The overall results indicate that OA may have a potential to be used as a dual(T and T2 based)contrast agent for PMMRA when proper sequence parameters are utilized.However,as the pilot study was based on limited number of animal hearts,more researches using OA in cadavers are needed to validate our findings.展开更多
Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to t...Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to traumatic investigation,acute hemorrhage,pulmonary parenchyma disease,calcification(calculus,atherosclerosis),and gas accumulation.Postmortem magnetic resonance(PMMR)has been proven to have advantages in soft tissue identification.Cardiac death is one of the keys and difficult points in forensic practice.With the introduction and development of PMCT angiography and PMMR,it was proved to be a very promising tool in the investigation of cardiac death,including vascular cavities and ischemic myocardium.This article reviewed the applications of the latest PMI and its related technologies in forensic cardiac pathology,including advantages,limitations,and development prospects.展开更多
Background:As traditional autopsy rates decline,the importance of forensic imaging,particularly postmortem computed tomography(PMCT),grows for non-invasive cause of death determination and evidence collection in legal...Background:As traditional autopsy rates decline,the importance of forensic imaging,particularly postmortem computed tomography(PMCT),grows for non-invasive cause of death determination and evidence collection in legal investigations,with unique considerations required for frozen corpses due to the lack of systematic imaging characteristic studies.Aims and Objectives:This study aims to fill the gap in current knowledge by systematically analyzing the PMCT imaging characteristics of frozen corpses.Materials and Methods:This study utilized postmortem computed tomography(PMCT)and postmortem computed tomography angiography(PMCTA)to examine tissue changes during the freezing and thawing process in a total of 61 corpses.Results:The results demonstrated that imaging changes in the brain were most pronounced during freezing and thawing,with a clear correlation to the duration of freezing/thawing and the position of the corpses.Typical ice crystal artifacts were observed in body fluids after freezing,while thawing led to a marked increase and redistribution of internal gas.Serial angiographic studies revealed"pseudo-brain hemorrhage"in the brainstem and cerebellum in several cases due to incomplete thawing and transport.Conclusion:This study provides a comprehensive analysis of the CT imaging characteristics of frozen corpses,elucidating the imaging features during the freezing and thawing processes.展开更多
Objective:The aim of the study was to introduce the development of forensic pathology for social-oriented forensic-identification institutions,using the Academy of Forensic Science as an example.Methods:Cases were col...Objective:The aim of the study was to introduce the development of forensic pathology for social-oriented forensic-identification institutions,using the Academy of Forensic Science as an example.Methods:Cases were collected from the Forensic Pathology Section of the Academy of Forensic Science and classified and organized according to gender,source,type,manner of death,and virtual autopsies of the cases over the years.Descriptive statistical analyses were performed using SPSS and Excel tables so as to summarize forensic pathology for social-oriented services.Results:A total of 12,161 cases were collected from the forensic pathology department;the most cases were from the People’s Public Security sources,and the fewest cases were from the Department of Health;the most cases were commissioned for the examination of cadaver surface in forensic medicine(8323 cases),and the fewest were for injury examination(72 cases)and diatom examination(78 cases);there were a total of 322 cases of virtual autopsy examination during the 11-year period,of which 33 cases were performed for target-organ arteriography;the highest number of cases for accidental death examinations(8122 cases).Conclusion:The Academy of Forensic Science and other social-service-oriented identification organizations undertake identification work on cases commissioned to them by the local and local people’s public security,people’s procuratorates,and people’s court systems.Virtual autopsy technology and other new technologies,new methods,and new standards to make up for the shortcomings of the traditional autopsy,to provide identification and research support,and subsequent prospective research to provide a database.展开更多
Virtopsy technology is noninvasive,noncontact,and can find potential lesions.For these reasons,it has broad application prospects in forensic pathology and forensic clinical science.The present article reviews the bri...Virtopsy technology is noninvasive,noncontact,and can find potential lesions.For these reasons,it has broad application prospects in forensic pathology and forensic clinical science.The present article reviews the brief history of virtopsy development,introduces the application of virtopsy in various fields of forensic medicine,summarizes the current situation regarding virtopsy in China,and puts forward suggestions for strengthening planning,setting standards,strengthening assistance,and promoting scientific research.展开更多
Background:Postmortem imaging has played an important role in the field of forensic medicine.Objective:To preliminarily explore the application value of cadaver imaging in mechanical injury.Methods:Three cases of mech...Background:Postmortem imaging has played an important role in the field of forensic medicine.Objective:To preliminarily explore the application value of cadaver imaging in mechanical injury.Methods:Three cases of mechanical injury were collected,and the external examination,postmortem computed tomography(PMCT),postmortem computed tomography angiography(PMCTA),and autopsy examination were performed in proper order to compare and analyze the diagnostic ability of postmortem imaging in the exploration of fractures,organ ruptures,and bleeding sources.Conclusion:Postmortem imaging(PMCT and PMCTA)has important application value in the analysis of cause of death,inference of injury objects,wound reconstruction,and search for bleeding sources.The combination of postmortem imaging and traditional anatomy can significantly imp rove the quality of forensic examinations.展开更多
基金This project was supported by a grant from China Scholarship Council(No.CSC 201707070113).
文摘Summary:Choosing proper perfusates as contrast agents is an important aspect for postmortem magnetic resonance angiography(PMMRA).However,in this emerging field,the number of suitable kinds of liquid is still very limited.The objective of this research is to compare MR images of oleic acid(OA)with paraffin oil(PO)in vitro and in ex situ animal hearts,in order to evaluate the feasibility to use OA as a novel contrast agent for PMMRA.In vitro,OA,PO and water(control)were introduced into three tubes separately and T,weighted-spin echo(Tw SE)and T2w-SE images were acquired on a 1.5T MR scanner.In the second experiment,0A and PO were injected into left coronary artery(LCA)and left ventricle(LV)of ex situ bovine hearts and their Tw-SE,Tzw-SE,Tw-multipoint Dixon(Tjw-mDixon)and 3DT2w-mDixon images were acquired.The overall results indicate that OA may have a potential to be used as a dual(T and T2 based)contrast agent for PMMRA when proper sequence parameters are utilized.However,as the pilot study was based on limited number of animal hearts,more researches using OA in cadavers are needed to validate our findings.
基金By grants from the National Key Research and Development Program of China(no.2022YFC3302002)the Council of National Science Foundation of China(grant number 82171872)+4 种基金the Council of National Science Foundation of Shanghai(grant number 21ZR1464600)Key Laboratory of judicial expertise of Ministry of Justice and Shanghai Key Laboratory of Forensic Medicine(grant number 21DZ2270800)Shanghai Forensic Service Platform(grant number 19DZ2292700)Central Research Institute Public Project(grant numbers2020Z‑4,2021G‑4)Shanghai Key Laboratory of Forensic Medicine,Key Lab of Forensic Science,Ministry of Justice(grant number KF202120).
文摘Postmortem imaging(PMI)technology known as virtual autopsy or virtopsy is regarded as a useful method of noninvasive or minimally invasive autopsy in forensic practice.Postmortem computed tomography is applicable to traumatic investigation,acute hemorrhage,pulmonary parenchyma disease,calcification(calculus,atherosclerosis),and gas accumulation.Postmortem magnetic resonance(PMMR)has been proven to have advantages in soft tissue identification.Cardiac death is one of the keys and difficult points in forensic practice.With the introduction and development of PMCT angiography and PMMR,it was proved to be a very promising tool in the investigation of cardiac death,including vascular cavities and ischemic myocardium.This article reviewed the applications of the latest PMI and its related technologies in forensic cardiac pathology,including advantages,limitations,and development prospects.
文摘Background:As traditional autopsy rates decline,the importance of forensic imaging,particularly postmortem computed tomography(PMCT),grows for non-invasive cause of death determination and evidence collection in legal investigations,with unique considerations required for frozen corpses due to the lack of systematic imaging characteristic studies.Aims and Objectives:This study aims to fill the gap in current knowledge by systematically analyzing the PMCT imaging characteristics of frozen corpses.Materials and Methods:This study utilized postmortem computed tomography(PMCT)and postmortem computed tomography angiography(PMCTA)to examine tissue changes during the freezing and thawing process in a total of 61 corpses.Results:The results demonstrated that imaging changes in the brain were most pronounced during freezing and thawing,with a clear correlation to the duration of freezing/thawing and the position of the corpses.Typical ice crystal artifacts were observed in body fluids after freezing,while thawing led to a marked increase and redistribution of internal gas.Serial angiographic studies revealed"pseudo-brain hemorrhage"in the brainstem and cerebellum in several cases due to incomplete thawing and transport.Conclusion:This study provides a comprehensive analysis of the CT imaging characteristics of frozen corpses,elucidating the imaging features during the freezing and thawing processes.
基金supported by grants from the Central Research Institute Public Project(GY2024D-1,GY2024Z-1)the National Natural Science Foundation of China(82171872)+5 种基金Shanghai Yangfan Special Programme(23YF1448700)Shanghai Key Laboratory of Forensic Medicine(21DZ2270800)Shanghai Forensic Service Platform,Key Laboratory of Forensic Science,Ministry of Justice,the Project of Shanghai Association of Forensic Science(SHSFJD2023-008)the 2023 Open Foundation of Key Laboratory of Forensic Pathology,Ministry of Public Security,P.R.China(GAFYBL202308)Guizhou“Hundred”High-level Innovative Talent Project,Qian Science Platform Talents(2020)6012-2Guizhou Scientific Support Project,Qian Science Support(2023)General 452.
文摘Objective:The aim of the study was to introduce the development of forensic pathology for social-oriented forensic-identification institutions,using the Academy of Forensic Science as an example.Methods:Cases were collected from the Forensic Pathology Section of the Academy of Forensic Science and classified and organized according to gender,source,type,manner of death,and virtual autopsies of the cases over the years.Descriptive statistical analyses were performed using SPSS and Excel tables so as to summarize forensic pathology for social-oriented services.Results:A total of 12,161 cases were collected from the forensic pathology department;the most cases were from the People’s Public Security sources,and the fewest cases were from the Department of Health;the most cases were commissioned for the examination of cadaver surface in forensic medicine(8323 cases),and the fewest were for injury examination(72 cases)and diatom examination(78 cases);there were a total of 322 cases of virtual autopsy examination during the 11-year period,of which 33 cases were performed for target-organ arteriography;the highest number of cases for accidental death examinations(8122 cases).Conclusion:The Academy of Forensic Science and other social-service-oriented identification organizations undertake identification work on cases commissioned to them by the local and local people’s public security,people’s procuratorates,and people’s court systems.Virtual autopsy technology and other new technologies,new methods,and new standards to make up for the shortcomings of the traditional autopsy,to provide identification and research support,and subsequent prospective research to provide a database.
基金Thisstudy was financially supported by National Social Science Fund Key Research Project“Research on Ethical Thinking and Legal Regulation of Medical Behavior in China from the Perspective of Doctor-Patient Relationship”(15AZD065)Key Consulting Research Project of the Chinese Academy of Engineering(2019-XZ-31).
文摘Virtopsy technology is noninvasive,noncontact,and can find potential lesions.For these reasons,it has broad application prospects in forensic pathology and forensic clinical science.The present article reviews the brief history of virtopsy development,introduces the application of virtopsy in various fields of forensic medicine,summarizes the current situation regarding virtopsy in China,and puts forward suggestions for strengthening planning,setting standards,strengthening assistance,and promoting scientific research.
基金supported by the 2023 National Key R and D Program Project(2023YFC3303901)the 2022 Ministry of Public Security Technical Research Program(2022JSYJC10).
文摘Background:Postmortem imaging has played an important role in the field of forensic medicine.Objective:To preliminarily explore the application value of cadaver imaging in mechanical injury.Methods:Three cases of mechanical injury were collected,and the external examination,postmortem computed tomography(PMCT),postmortem computed tomography angiography(PMCTA),and autopsy examination were performed in proper order to compare and analyze the diagnostic ability of postmortem imaging in the exploration of fractures,organ ruptures,and bleeding sources.Conclusion:Postmortem imaging(PMCT and PMCTA)has important application value in the analysis of cause of death,inference of injury objects,wound reconstruction,and search for bleeding sources.The combination of postmortem imaging and traditional anatomy can significantly imp rove the quality of forensic examinations.
