While the recent release of the Chinese tree shrew (Tupaia belangeri chinensis) genome has made the tree shrew an increasingly viable experimental animal model for biomedical research, further study of the genome ma...While the recent release of the Chinese tree shrew (Tupaia belangeri chinensis) genome has made the tree shrew an increasingly viable experimental animal model for biomedical research, further study of the genome may facilitate new insights into the applicability of this model. For example, though the tree shrew has a rapid rate of speed and strong jumping ability, there are limited studies on its locomotion ability. In this study we used the available Chinese tree shrew genome information and compared the evolutionary pattern of 407 locomotion system related orthologs among five mammals (human, rhesus monkey, mouse, rat and dog) and the Chinese tree shrew. Our analyses identified 29 genes with significantly high co (Ka/Ks ratio) values and 48 amino acid sites in 14 genes showed significant evidence of positive selection in the Chinese tree shrew. Some of these positively selected genes, e.g. HOXA6 (homeobox A6) and AVP (arginine vasopressin), play important roles in muscle contraction or skeletal morphogenesis. These results provide important clues in understanding the genetic bases of locomotor adaptation in the Chinese tree shrew.展开更多
By constructing two suitable generalized Lyapunov functions,we derived a generalized ellipsoidal estimate of the globally attractive set and positively invariant set of the unified chaotic system with the parameters ...By constructing two suitable generalized Lyapunov functions,we derived a generalized ellipsoidal estimate of the globally attractive set and positively invariant set of the unified chaotic system with the parameters α=1/29 and 1/29<α<2/29,respectively,which extends some related results of Li,et al. [Li DM,Lu JA,Wu XQ,Chen GR,Estimating the global basin of attraction and positively invariant set for the Lorenz system and a unified chaotic system,Journal of Mathematical Analysis and Applications,2006,323(2): 844-853]. The theoretical results obtained in this paper will find wide application in chaos control and synchronization.展开更多
To develop a depth filter based on the electrostatic adsorption principle, positively charged microporous ceramic membrane was prepared from a diatomaceous earth ceramic membrane.The internal surface of the highly por...To develop a depth filter based on the electrostatic adsorption principle, positively charged microporous ceramic membrane was prepared from a diatomaceous earth ceramic membrane.The internal surface of the highly porous ceramic membrane was coated with uniformly distributed electropositive nano-Y2O3 coating. The dye removal performance was evaluated through pressurized filtration tests using Titan Yellow aqueous solution. It showed that positively charged microporous ceramic membrane exhibited a flow rate of 421 L/(m^2·hr) under the trans-membrane pressure of 0.03 bar. Moreover it could effectively remove Titan Yellow with feed concentration of 10 mg/L between pH 3 to 8. The removal rate increased with the enhancement of the surface charge properties with a maximum rejection of 99.6%. This study provides a new and feasible method of removing organic dyes in wastewater. It is convinced that there will be a broad market for the application of charged ceramic membrane in the field of dye removal or recovery from industry wastewater.展开更多
The empirical likelihood is used to propose a new class of quantile estimators in the presence of some auxiliary information under positively associated samples. It is shown that the proposed quantile estimators are a...The empirical likelihood is used to propose a new class of quantile estimators in the presence of some auxiliary information under positively associated samples. It is shown that the proposed quantile estimators are asymptotically normally distributed with smaller asymptotic variances than those of the usual quantile estimators.展开更多
A selfmade positively charged nanofiltration (NF) membrane was used to treat textile dye effluent to generate water for reuse, and the factors affecting nanofiltration process such as operating pressure, feed flow a...A selfmade positively charged nanofiltration (NF) membrane was used to treat textile dye effluent to generate water for reuse, and the factors affecting nanofiltration process such as operating pressure, feed flow and membrane cleaning were investigated. With an applied pressure of 1.0 MPa and a feed flow of 40 L/h, this NF membrane has a removal of 93.3% for CODor and a reduction of approximately 51.0% in TDS, salinity and conductivity achieving the chroma removal of 100%. The permeate obtained through this membrane is suitable for recycling. Moreover, the membrane could be reused after being cleaned with 1% NaOH solution.展开更多
A generalized Lyapunov function was employed to investigate the ultimate bound and positively invariant set of a generalized Lorenz system.We derived an ellipsoidal estimate of the ultimate bound and positively invari...A generalized Lyapunov function was employed to investigate the ultimate bound and positively invariant set of a generalized Lorenz system.We derived an ellipsoidal estimate of the ultimate bound and positively invariant set for the generalized Lorenz system,for all the positive values of system parameters a,b,and c.Our results extend the related result of Li,et al.[Li DM,Lu JA,Wu XQ,et al.,Estimating the ultimate bound and positively invariant set for the Lorenz system and a unified chaotic system,Journal of Mathematical Analysis and Application,2006,323(2):844-653].展开更多
A new positively thermo-sensitive hydrogel was designed and synthesized by a condensation polymerization reaction of ethylenediaminetetraacetic dianhydride(EDTAD) and piperazine(PA) to give poly(ethylenediaminete...A new positively thermo-sensitive hydrogel was designed and synthesized by a condensation polymerization reaction of ethylenediaminetetraacetic dianhydride(EDTAD) and piperazine(PA) to give poly(ethylenediaminetetraacetic dianhydride-copiperazine) (PEP).The obtained polymers' structure was characterized by FTIR and ^(13)C NMR.The backbone of the polymer linked by amide bond and abundant of carboxyl groups as pendant group could form strong intermolecular and intramolecular hydrogen bond at lower temperature and dissociate at higher temperature,resulting in the polymer with thermo-sensitivity.The aqueous solution of PEP at lower temperature(〈20℃) showed micro-gel formation and transformed to transparent solution at higher temperature(〉40℃).Transition temperature shifted to higher value with the increasing of concentration.The hydrogel exhibited reversible phase transition and the transmittance change was not weakened by multiple temperature changes.展开更多
In a steady-state plasma,the loss rate of plasma particles to the chamber wall and surfaces in contact with plasma is balanced by the ionization rate of background neutrals in the hot-filament discharges.The balance b...In a steady-state plasma,the loss rate of plasma particles to the chamber wall and surfaces in contact with plasma is balanced by the ionization rate of background neutrals in the hot-filament discharges.The balance between the loss rate and ionization rate of plasma particles(electrons and ions)maintains quasi-neutrality of the bulk plasma.In the presence of an external perturbation,it tries to retain its quasi-neutrality condition.In this work,we studied how the properties of bulk plasma are affected by an external DC potential perturbation.An auxiliary biased metal disk electrode was used to introduce a potential perturbation to the plasma medium.A single Langmuir probe and an emissive probe,placed in the line of the discharge axis,were used for the characterization of the bulk plasma.It is observed that only positive bias to the auxiliary metal disk increases the plasma potential,electron temperature,and plasma density but these plasma parameters remain unaltered when the disk is biased with a negative potential with respect to plasma potential.The observed plasma parameters for two different-sized,positively as well as negatively biased,metal disks are compared and found inconsistent with the existing theoretical model at large positive bias voltages.The role of the primary energetic electrons population in determining the plasma parameters is discussed.The experimentally observed results are qualitatively explained on the basis of electrostatic confinement arising due to the loss of electrons to a biased metal disk electrode.展开更多
An efficient algorithm is proposed for computing the solution to the constrained finite time optimal control (CFTOC) problem for discrete-time piecewise affine (PWA) systems with a quadratic performance index. The...An efficient algorithm is proposed for computing the solution to the constrained finite time optimal control (CFTOC) problem for discrete-time piecewise affine (PWA) systems with a quadratic performance index. The maximal positively invariant terminal set, which is feasible and invariant with respect to a feedback control law, is computed as terminal target set and an associated Lyapunov function is chosen as terminal cost. The combination of these two components guarantees constraint satisfaction and closed-loop stability for all time. The proposed algorithm combines a dynamic programming strategy with a multi-parametric quadratic programming solver and basic polyhedral manipulation. A numerical example shows that a larger stabilizable set of states can be obtained by the proposed algorithm than precious work.展开更多
Using the method of few-body physics,we obtain the relation between the correlation energies of the low-lying states of the positively charged exciton X+and the radius of quantum dots.We also calculate the binding ene...Using the method of few-body physics,we obtain the relation between the correlation energies of the low-lying states of the positively charged exciton X+and the radius of quantum dots.We also calculate the binding energies of the ground state of a positively charged exciton as a function of the electron-to-hole mass ratio for a few values of the strength of the confinement.We find that there exists a critical mass ratioσ^(c),such that ifσ>σ^(c)(σ<σ^(c))the X^(+)configuration is stable(unstable),andσc increases as the strength of the confinement increases.展开更多
Molluscs are one of the most diverse groups of animals and exhibit a rich and diverse variety of form and lifestyle. Most molluscs live with a free-moving lifestyle, while some molluscs are sessile. The adaptation to ...Molluscs are one of the most diverse groups of animals and exhibit a rich and diverse variety of form and lifestyle. Most molluscs live with a free-moving lifestyle, while some molluscs are sessile. The adaptation to the two distinct lifestyles required complex changes, from molecules to organs, and physiology to morphology. In this study, we conducted a genome-wide scan for positive selection by comparing the available genomes of two sessile molluscs with four free-moving molluscs. A total of 40 genes were identified undergoing positive selection in the sessile molluscs by the branch-site model. Functional characterization showed that they were mainly enriched in two pathways, Oxidative phosphorylation(OXPHOS) and TGF-beta signaling pathway. The unexpected positive selection on OXPHOS genes in sessile molluscs suggests that the adaptation of OXPHOS involves many factors beyond enhancing ATP production. A modified OXPHOS regulatory system may allow sessile molluscs to better cope with biotic and abiotic stresses. Moreover, positively selected genes in TGF-beta signaling pathway probably have played a key role in the patterning of body plans and growth in metazoans. We speculate that these genes are associated with the body structure and organic adaptation to a sedentary lifestyle in sessile bivalve molluscs.展开更多
Let M be a closed n-manifold of positive sectional curvature. Assume that M admits an effective isometrical T1× Zpk-action with p prime. The main result of the article n+1 for n 〉 5, then there exists a positiv...Let M be a closed n-manifold of positive sectional curvature. Assume that M admits an effective isometrical T1× Zpk-action with p prime. The main result of the article n+1 for n 〉 5, then there exists a positive constant p(n), is that ifk=lforn=3or k〉 n+1/4 for n≥5,then there exists a positive constant p(n),depending only on n, such that π1 (M) is cyclic if p ≥ p(n).展开更多
In this paper we have developed a model to study the role of both electron and ion nonthermalities on dust acoustic wave propagation in a complex plasma in presence of positively charged dust grains. Secondary electro...In this paper we have developed a model to study the role of both electron and ion nonthermalities on dust acoustic wave propagation in a complex plasma in presence of positively charged dust grains. Secondary electron emission from dust grains has been considered as the source of positive dust charging. As secondary emission current depends on the flux of primary electrons, nonthermality of primary electrons changes the expression of secondary emission current from that of earlier work where primary electrons were thermal. Expression of nonthermal electron current flowing to the positively charged dust grains and consequently the expression of secondary electron current flowing out of the dust grains have been first time calculated in this paper, whereas the expression for nonthermal ion current flowing to the positively charged dust grains is present in existing literature. Dispersion relation of dust acoustic wave has been derived. From this dispersion relation real frequency and growth rate of the wave have been calculated. Results have been plotted for different strength of nonthermalities of electrons and ions.展开更多
The plant cell wall is an important interface for sensing pathogen attack and activating signaling pathways that promote plant immune responses.THESEUS1(THE1) acts as a sensor of cell wall integrity that controls cell...The plant cell wall is an important interface for sensing pathogen attack and activating signaling pathways that promote plant immune responses.THESEUS1(THE1) acts as a sensor of cell wall integrity that controls cell elongation during plant growth.However, no specific role for THE1 in plant defense responses has been reported. Here, we found that THE1 interacts with GUANINE EXCHANGE FACTOR4(GEF4)and that both proteins play regulatory roles in plant resistance to the necrotrophic fungus Botrytis cinerea.Genetic analysis showed that THE1 and GEF4 function in the same genetic pathway to mediate plant defense responses. In addition, using transcriptome analysis, we identified various genes(such as defense-related,secondary metabolite-related, and transcription factor genes) that are likely downstream targets in the THE1-GEF4 signaling pathway. Our results suggest that THE1 functions as an upstream regulator of GEF4 signaling to positively regulate defense responses against B. cinerea in Arabidopsis.展开更多
Alternate adsorption of positively charged colloid-Au nanoparticles(nano-Au^(⊕))and negatively charged hemoglobin(Hb)on L-cysteine(L-cys)modified gold electrode resulted in the assembly of{Hb/nano-Au^(⊕)}n layer-by-...Alternate adsorption of positively charged colloid-Au nanoparticles(nano-Au^(⊕))and negatively charged hemoglobin(Hb)on L-cysteine(L-cys)modified gold electrode resulted in the assembly of{Hb/nano-Au^(⊕)}n layer-by-layer films/L-cys modified gold electrode.The nano-Au^(⊕)was characterized by transmission electron micrograph(TEM)and microelectrophoresis.The modified electrode interface morphology was characterized by electrochemical impedance spectroscopy(EIS),atomic force mi-croscopy(AFM),cyclic voltammograms(CV)and chronoamperometry.Direct electron transfer between hemoglobin and gold electrodes was studied,and the apparent Michaelis-Menten constant(k_(m)^(app))of the modified electrode was evaluated to be 0.10 mmol·L^(-1).Moreover,the higher activity of proteins in the nano-Au^(⊕)films could be retained compared with the electropolymerization membrane,since the pro-teins in nano-Au^(⊕)films retained their near-native structure.Direct electron transfer between hemoglo-bin and electrode and electrochemically catalyzed reduction of hydrogen peroxide on a modified elec-trode was studied,and the linear range was from 2.1×10^(-8)to 1.2×10^(-3)mol·L^(-1)(r=0.994)with a detection limit of 1.1×10^(-8)mol·L^(-1)H_(2)O_(2).展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
Let M be a complete Riemannian manifold, Δ its Laplace-Beltrami operator, V its gradient operator. The Riesz transform ▽(-Δ)-1/2-was first introduced by R. S. Stritrartz, who proved its L^2-boundedness for the gene...Let M be a complete Riemannian manifold, Δ its Laplace-Beltrami operator, V its gradient operator. The Riesz transform ▽(-Δ)-1/2-was first introduced by R. S. Stritrartz, who proved its L^2-boundedness for the general case and its展开更多
Certain problems concerning state constraints and control constraints can often be reduced to the study of positive invariance of some subsets of the state space of dynamical systems. The robust positive invariance of...Certain problems concerning state constraints and control constraints can often be reduced to the study of positive invariance of some subsets of the state space of dynamical systems. The robust positive invariance of given linear state constraint sets of uncertain discrete-time systems is studied by the mixed monotone decomposition method. Necessary and suffi-展开更多
The detection of protein/small molecule interactions plays important roles in drug discovery and protein/metabolite interactions in biology. In this work, by coupling the terminal protection of small molecule-linked s...The detection of protein/small molecule interactions plays important roles in drug discovery and protein/metabolite interactions in biology. In this work, by coupling the terminal protection of small molecule-linked ss DNA strategy with the unmodified and positively charged gold nanoparticle((+)Au NP) nanoprobes, we have developed a sensitive and simple colorimetric sensor for the detection of folate receptor, a highly expressed protein in many kinds of malignant tumors. The target folate receptor binds the folate moieties of the folate-linked ss DNA through high affinity interactions and protects the protein-bound ss DNA from digestion by exonuclease I. The protected ss DNA thus adsorbs the((+)Au NP) through electrostatic interactions, leading to a red-to-blue color change of the sensing solution for sensitive colorimetric detection of folate receptor at the sub-nanomolar level. Besides, this colorimetric sensor shows high selectivity toward folate receptor against other control proteins. The developed sensor avoids the modification/conjugation of the Au NP nanoprobes and the involvement of any expensive instruments for signal transduction in protein detection. Featured with these obvious advantages, the colorimetric sensor strategy demonstrated herein can be easily expanded for sensitive and convenient detection of various protein/small molecule interactions.展开更多
We study the space of positively expansive differentiable maps of a compact connected C ∞ Riemannian manifold without boundary. It is proved that (i) the C1-interior of the set of positively expansive differentiabl...We study the space of positively expansive differentiable maps of a compact connected C ∞ Riemannian manifold without boundary. It is proved that (i) the C1-interior of the set of positively expansive differentiable maps coincides with the set of expanding maps, and (ii) Cl-generically, a differentiable map is positively expansive if and only if it is expanding.展开更多
基金Foundation items: This study was supported by the National 863 Project of China (2012AA021801, 2012AA022402) and grants from Chinese Academy of Sciences (KSCX2-EW-R-11, KSCX2-EW-J23) and Yunnan Province (2013FB071)Acknowledgements: We are grateful to Dr. Dong WANG for helpful discussion.
文摘While the recent release of the Chinese tree shrew (Tupaia belangeri chinensis) genome has made the tree shrew an increasingly viable experimental animal model for biomedical research, further study of the genome may facilitate new insights into the applicability of this model. For example, though the tree shrew has a rapid rate of speed and strong jumping ability, there are limited studies on its locomotion ability. In this study we used the available Chinese tree shrew genome information and compared the evolutionary pattern of 407 locomotion system related orthologs among five mammals (human, rhesus monkey, mouse, rat and dog) and the Chinese tree shrew. Our analyses identified 29 genes with significantly high co (Ka/Ks ratio) values and 48 amino acid sites in 14 genes showed significant evidence of positive selection in the Chinese tree shrew. Some of these positively selected genes, e.g. HOXA6 (homeobox A6) and AVP (arginine vasopressin), play important roles in muscle contraction or skeletal morphogenesis. These results provide important clues in understanding the genetic bases of locomotor adaptation in the Chinese tree shrew.
文摘By constructing two suitable generalized Lyapunov functions,we derived a generalized ellipsoidal estimate of the globally attractive set and positively invariant set of the unified chaotic system with the parameters α=1/29 and 1/29<α<2/29,respectively,which extends some related results of Li,et al. [Li DM,Lu JA,Wu XQ,Chen GR,Estimating the global basin of attraction and positively invariant set for the Lorenz system and a unified chaotic system,Journal of Mathematical Analysis and Applications,2006,323(2): 844-853]. The theoretical results obtained in this paper will find wide application in chaos control and synchronization.
基金supported by the National Natural Science Foundation of China (No. 51202292)
文摘To develop a depth filter based on the electrostatic adsorption principle, positively charged microporous ceramic membrane was prepared from a diatomaceous earth ceramic membrane.The internal surface of the highly porous ceramic membrane was coated with uniformly distributed electropositive nano-Y2O3 coating. The dye removal performance was evaluated through pressurized filtration tests using Titan Yellow aqueous solution. It showed that positively charged microporous ceramic membrane exhibited a flow rate of 421 L/(m^2·hr) under the trans-membrane pressure of 0.03 bar. Moreover it could effectively remove Titan Yellow with feed concentration of 10 mg/L between pH 3 to 8. The removal rate increased with the enhancement of the surface charge properties with a maximum rejection of 99.6%. This study provides a new and feasible method of removing organic dyes in wastewater. It is convinced that there will be a broad market for the application of charged ceramic membrane in the field of dye removal or recovery from industry wastewater.
基金supported by the National Natural Science Foundation of China(11271088,11361011,11201088)the Natural Science Foundation of Guangxi(2013GXNSFAA019004,2013GXNSFAA019007,2013GXNSFBA019001)
文摘The empirical likelihood is used to propose a new class of quantile estimators in the presence of some auxiliary information under positively associated samples. It is shown that the proposed quantile estimators are asymptotically normally distributed with smaller asymptotic variances than those of the usual quantile estimators.
基金Funded by the Major State Basic Research Development Program of China (973 Program)( No.2003CB615706)
文摘A selfmade positively charged nanofiltration (NF) membrane was used to treat textile dye effluent to generate water for reuse, and the factors affecting nanofiltration process such as operating pressure, feed flow and membrane cleaning were investigated. With an applied pressure of 1.0 MPa and a feed flow of 40 L/h, this NF membrane has a removal of 93.3% for CODor and a reduction of approximately 51.0% in TDS, salinity and conductivity achieving the chroma removal of 100%. The permeate obtained through this membrane is suitable for recycling. Moreover, the membrane could be reused after being cleaned with 1% NaOH solution.
文摘A generalized Lyapunov function was employed to investigate the ultimate bound and positively invariant set of a generalized Lorenz system.We derived an ellipsoidal estimate of the ultimate bound and positively invariant set for the generalized Lorenz system,for all the positive values of system parameters a,b,and c.Our results extend the related result of Li,et al.[Li DM,Lu JA,Wu XQ,et al.,Estimating the ultimate bound and positively invariant set for the Lorenz system and a unified chaotic system,Journal of Mathematical Analysis and Application,2006,323(2):844-653].
基金supported by the National Natural Science Foundation of China(No.30870609)
文摘A new positively thermo-sensitive hydrogel was designed and synthesized by a condensation polymerization reaction of ethylenediaminetetraacetic dianhydride(EDTAD) and piperazine(PA) to give poly(ethylenediaminetetraacetic dianhydride-copiperazine) (PEP).The obtained polymers' structure was characterized by FTIR and ^(13)C NMR.The backbone of the polymer linked by amide bond and abundant of carboxyl groups as pendant group could form strong intermolecular and intramolecular hydrogen bond at lower temperature and dissociate at higher temperature,resulting in the polymer with thermo-sensitivity.The aqueous solution of PEP at lower temperature(〈20℃) showed micro-gel formation and transformed to transparent solution at higher temperature(〉40℃).Transition temperature shifted to higher value with the increasing of concentration.The hydrogel exhibited reversible phase transition and the transmittance change was not weakened by multiple temperature changes.
文摘In a steady-state plasma,the loss rate of plasma particles to the chamber wall and surfaces in contact with plasma is balanced by the ionization rate of background neutrals in the hot-filament discharges.The balance between the loss rate and ionization rate of plasma particles(electrons and ions)maintains quasi-neutrality of the bulk plasma.In the presence of an external perturbation,it tries to retain its quasi-neutrality condition.In this work,we studied how the properties of bulk plasma are affected by an external DC potential perturbation.An auxiliary biased metal disk electrode was used to introduce a potential perturbation to the plasma medium.A single Langmuir probe and an emissive probe,placed in the line of the discharge axis,were used for the characterization of the bulk plasma.It is observed that only positive bias to the auxiliary metal disk increases the plasma potential,electron temperature,and plasma density but these plasma parameters remain unaltered when the disk is biased with a negative potential with respect to plasma potential.The observed plasma parameters for two different-sized,positively as well as negatively biased,metal disks are compared and found inconsistent with the existing theoretical model at large positive bias voltages.The role of the primary energetic electrons population in determining the plasma parameters is discussed.The experimentally observed results are qualitatively explained on the basis of electrostatic confinement arising due to the loss of electrons to a biased metal disk electrode.
基金supported by the National Natural Science Foundation of China (60702033)Natural Science Foundation of Zhe-jiang Province (Y107440)
文摘An efficient algorithm is proposed for computing the solution to the constrained finite time optimal control (CFTOC) problem for discrete-time piecewise affine (PWA) systems with a quadratic performance index. The maximal positively invariant terminal set, which is feasible and invariant with respect to a feedback control law, is computed as terminal target set and an associated Lyapunov function is chosen as terminal cost. The combination of these two components guarantees constraint satisfaction and closed-loop stability for all time. The proposed algorithm combines a dynamic programming strategy with a multi-parametric quadratic programming solver and basic polyhedral manipulation. A numerical example shows that a larger stabilizable set of states can be obtained by the proposed algorithm than precious work.
基金Supported by the National Natural Science Foundation of China under Grant No.19975013the Natural Science Foundation of Guangdong Province。
文摘Using the method of few-body physics,we obtain the relation between the correlation energies of the low-lying states of the positively charged exciton X+and the radius of quantum dots.We also calculate the binding energies of the ground state of a positively charged exciton as a function of the electron-to-hole mass ratio for a few values of the strength of the confinement.We find that there exists a critical mass ratioσ^(c),such that ifσ>σ^(c)(σ<σ^(c))the X^(+)configuration is stable(unstable),andσc increases as the strength of the confinement increases.
基金supported by the grants from the National Natural Science Foundation of China(No.3137 2524)the Shandong Seed Project,Shandong Province(No.2014GHY115002)+1 种基金the Fundamental Research Funds for the Central Universities(No.201762014)Qingdao National Laboratory for Marine Science and Technology(No.2016LMFS-A06)
文摘Molluscs are one of the most diverse groups of animals and exhibit a rich and diverse variety of form and lifestyle. Most molluscs live with a free-moving lifestyle, while some molluscs are sessile. The adaptation to the two distinct lifestyles required complex changes, from molecules to organs, and physiology to morphology. In this study, we conducted a genome-wide scan for positive selection by comparing the available genomes of two sessile molluscs with four free-moving molluscs. A total of 40 genes were identified undergoing positive selection in the sessile molluscs by the branch-site model. Functional characterization showed that they were mainly enriched in two pathways, Oxidative phosphorylation(OXPHOS) and TGF-beta signaling pathway. The unexpected positive selection on OXPHOS genes in sessile molluscs suggests that the adaptation of OXPHOS involves many factors beyond enhancing ATP production. A modified OXPHOS regulatory system may allow sessile molluscs to better cope with biotic and abiotic stresses. Moreover, positively selected genes in TGF-beta signaling pathway probably have played a key role in the patterning of body plans and growth in metazoans. We speculate that these genes are associated with the body structure and organic adaptation to a sedentary lifestyle in sessile bivalve molluscs.
文摘Let M be a closed n-manifold of positive sectional curvature. Assume that M admits an effective isometrical T1× Zpk-action with p prime. The main result of the article n+1 for n 〉 5, then there exists a positive constant p(n), is that ifk=lforn=3or k〉 n+1/4 for n≥5,then there exists a positive constant p(n),depending only on n, such that π1 (M) is cyclic if p ≥ p(n).
文摘In this paper we have developed a model to study the role of both electron and ion nonthermalities on dust acoustic wave propagation in a complex plasma in presence of positively charged dust grains. Secondary electron emission from dust grains has been considered as the source of positive dust charging. As secondary emission current depends on the flux of primary electrons, nonthermality of primary electrons changes the expression of secondary emission current from that of earlier work where primary electrons were thermal. Expression of nonthermal electron current flowing to the positively charged dust grains and consequently the expression of secondary electron current flowing out of the dust grains have been first time calculated in this paper, whereas the expression for nonthermal ion current flowing to the positively charged dust grains is present in existing literature. Dispersion relation of dust acoustic wave has been derived. From this dispersion relation real frequency and growth rate of the wave have been calculated. Results have been plotted for different strength of nonthermalities of electrons and ions.
基金supported by the National Natural Science Foundation of China(31400221)the Beijing Advanced Innovation Center for Tree Breeding by Molecular Design+1 种基金the Program for Changjiang Scholars and Innovative Research Team in University(IRT13047)the Fundamental Research Funds for the Central Universities(BLX2012038)
文摘The plant cell wall is an important interface for sensing pathogen attack and activating signaling pathways that promote plant immune responses.THESEUS1(THE1) acts as a sensor of cell wall integrity that controls cell elongation during plant growth.However, no specific role for THE1 in plant defense responses has been reported. Here, we found that THE1 interacts with GUANINE EXCHANGE FACTOR4(GEF4)and that both proteins play regulatory roles in plant resistance to the necrotrophic fungus Botrytis cinerea.Genetic analysis showed that THE1 and GEF4 function in the same genetic pathway to mediate plant defense responses. In addition, using transcriptome analysis, we identified various genes(such as defense-related,secondary metabolite-related, and transcription factor genes) that are likely downstream targets in the THE1-GEF4 signaling pathway. Our results suggest that THE1 functions as an upstream regulator of GEF4 signaling to positively regulate defense responses against B. cinerea in Arabidopsis.
基金Supported by the National Natural Science Foundation of China(Grant No.20675064)the Natural Science Foundation of Chongqing City,China(Grant Nos.CSTC-2004 BB4149,2005 BB4100)High Technology Project Foundation of Southwest University(Grant No.XSGX02)
文摘Alternate adsorption of positively charged colloid-Au nanoparticles(nano-Au^(⊕))and negatively charged hemoglobin(Hb)on L-cysteine(L-cys)modified gold electrode resulted in the assembly of{Hb/nano-Au^(⊕)}n layer-by-layer films/L-cys modified gold electrode.The nano-Au^(⊕)was characterized by transmission electron micrograph(TEM)and microelectrophoresis.The modified electrode interface morphology was characterized by electrochemical impedance spectroscopy(EIS),atomic force mi-croscopy(AFM),cyclic voltammograms(CV)and chronoamperometry.Direct electron transfer between hemoglobin and gold electrodes was studied,and the apparent Michaelis-Menten constant(k_(m)^(app))of the modified electrode was evaluated to be 0.10 mmol·L^(-1).Moreover,the higher activity of proteins in the nano-Au^(⊕)films could be retained compared with the electropolymerization membrane,since the pro-teins in nano-Au^(⊕)films retained their near-native structure.Direct electron transfer between hemoglo-bin and electrode and electrochemically catalyzed reduction of hydrogen peroxide on a modified elec-trode was studied,and the linear range was from 2.1×10^(-8)to 1.2×10^(-3)mol·L^(-1)(r=0.994)with a detection limit of 1.1×10^(-8)mol·L^(-1)H_(2)O_(2).
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
文摘Let M be a complete Riemannian manifold, Δ its Laplace-Beltrami operator, V its gradient operator. The Riesz transform ▽(-Δ)-1/2-was first introduced by R. S. Stritrartz, who proved its L^2-boundedness for the general case and its
文摘Certain problems concerning state constraints and control constraints can often be reduced to the study of positive invariance of some subsets of the state space of dynamical systems. The robust positive invariance of given linear state constraint sets of uncertain discrete-time systems is studied by the mixed monotone decomposition method. Necessary and suffi-
基金supported by the National Natural Science Foundation of China (21505010, 21173274)Chongqing Research Program of Basic Research and Frontier Technology (cstc2015jcyj A1357)Scientific Research Innovation Team of Chongqing University of Technology (2015TD22)
文摘The detection of protein/small molecule interactions plays important roles in drug discovery and protein/metabolite interactions in biology. In this work, by coupling the terminal protection of small molecule-linked ss DNA strategy with the unmodified and positively charged gold nanoparticle((+)Au NP) nanoprobes, we have developed a sensitive and simple colorimetric sensor for the detection of folate receptor, a highly expressed protein in many kinds of malignant tumors. The target folate receptor binds the folate moieties of the folate-linked ss DNA through high affinity interactions and protects the protein-bound ss DNA from digestion by exonuclease I. The protected ss DNA thus adsorbs the((+)Au NP) through electrostatic interactions, leading to a red-to-blue color change of the sensing solution for sensitive colorimetric detection of folate receptor at the sub-nanomolar level. Besides, this colorimetric sensor shows high selectivity toward folate receptor against other control proteins. The developed sensor avoids the modification/conjugation of the Au NP nanoprobes and the involvement of any expensive instruments for signal transduction in protein detection. Featured with these obvious advantages, the colorimetric sensor strategy demonstrated herein can be easily expanded for sensitive and convenient detection of various protein/small molecule interactions.
基金Supported by JSPD Gtant-in-Aid for Scientific Research (C)(Grant No.19540209)
文摘We study the space of positively expansive differentiable maps of a compact connected C ∞ Riemannian manifold without boundary. It is proved that (i) the C1-interior of the set of positively expansive differentiable maps coincides with the set of expanding maps, and (ii) Cl-generically, a differentiable map is positively expansive if and only if it is expanding.