National Population Health Data Center(NPHDC)is one of China's 20 national-level science data centers,jointly designated by the Ministry of Science and Technology and the Ministry of Finance.Operated by the Chines...National Population Health Data Center(NPHDC)is one of China's 20 national-level science data centers,jointly designated by the Ministry of Science and Technology and the Ministry of Finance.Operated by the Chinese Academy of Medical Sciences under the oversight of the National Health Commission,NPHDC adheres to national regulations including the Scientific Data Management Measures and the National Science and Technology Infrastructure Service Platform Management Measures,and is committed to collecting,integrating,managing,and sharing biomedical and health data through openaccess platform,fostering open sharing and engaging in international cooperation.展开更多
The aim of the study is to identify sources of atmospheric pollutants and assess their impact on the health of Conakry’s population. Ten contaminant sources were identified. Sampling was conducted on suspended partic...The aim of the study is to identify sources of atmospheric pollutants and assess their impact on the health of Conakry’s population. Ten contaminant sources were identified. Sampling was conducted on suspended particles and gases. Physicochemical methods were used to determine pollutant levels. The results show that CO2 is the highest gaseous pollutant at the Dar es Salaam landfill (708 μg/m3), followed by CO (354 μg/m3). The highest content of volatile organic compounds (VOC) was observed at the Tombo thermal power plant (475 μg/m3). Nitrogen oxides and hydrocarbon pollutants (NOx and CnH2n+2) at each site were relatively stable, with levels between (100 - 150 μg/m3) and (450 μg/m3), respectively. Suspended particulates (PM10 and PM2.5) measured at various locations showed higher PM10 levels than PM2.5. In particular, the highest PM10 content was observed at the Sangoyah soap factory (410 μg/m3), followed by the Madina market (319 μg/m3) and the Dar-Es-Salam landfill (318 μg/m3). As indicated by the results, these contamination levels far exceed European and World Health Organization standards. This study highlights the need to adopt a strategy to reduce pollution levels at these critical points to protect the health of the city’s population.展开更多
Against the backdrop of global warming,China has been facing increasingly frequent and severe extreme weather and climate events,with a prominent risk of compound extreme events induced by interactions among multiple ...Against the backdrop of global warming,China has been facing increasingly frequent and severe extreme weather and climate events,with a prominent risk of compound extreme events induced by interactions among multiple climate drivers and/or hazards.The present study first reviews the definition and classification of compound extreme events in China.Then,it summarizes research progress on the evolutionary characteristics,formation mechanisms,and future projections of different types of compound extreme events.The potential risks and possible impact pathways of three specific event types—namely,continuous day–night hot extremes,temperature–humidity compound events,and high-temperature–ozone compound events—on the health of the Chinese population are then explored.Finally,a framework for assessing the hazard risk of compound extreme events is constructed,accompanied by response strategies based on carbon neutrality targets.Building on existing research achievements,five future research directions are proposed:(1)identifying the risk chains of compound events;(2)addressing the constraints of observational records and coupled model performances;(3)attributing and understanding the drivers of compound extreme events;(4)finding optimal pathways for carbon reduction and air quality improvement;and(5)promoting inter-disciplinary,multi-regional,and cross-sectoral collaboration.Strengthening research in these directions will deepen our understanding of compound extreme events and provide technological support for climate change adaptation and health risk responses in China.展开更多
Chronic diseases,or NCDs(noncommunicable diseases),constitute a major global health challenge,causing millions of deaths and imposing substantial economic burdens annually.This paper introduces the Health Score,a comp...Chronic diseases,or NCDs(noncommunicable diseases),constitute a major global health challenge,causing millions of deaths and imposing substantial economic burdens annually.This paper introduces the Health Score,a comprehensive framework for assessing chronic disease risk by integrating diverse determinants of health,including social,economic,environmental,behavioral,treatment,culture,and nature factors.The Health Score,ranging from 0 to 850,quantifies indivi dual and population-level health risks while identifying protective factors through a structured methodology that supports targeted interventions at individual,corporate,and community scales.The paper highlights the rising prevalence of chronic diseases in the United States,projecting that nearly half of the population will be affected by 2030,alongside a global economic burden expected to reach trillions of dollars.Existing surveillance tools,such as the CDS(Chronic Disease Score)and CDIs(Chronic Disease Indicators),are examined for their roles in monitoring health disparities.The Health Score advances a holistic,proactive approach,emphasizing lifestyle modifications,equitable healthcare access,economic opportunities,social support,nature exposure,cu ltural awareness,and community engagement.By elucidating the complex interplay of health determinants,this framework equips stakeholders with actionable insights to implement effective prevention strategies,ultimately fostering healthier,more resi lient populations.展开更多
Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed...Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.展开更多
Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data stud...Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.展开更多
A fundamental paradox of the health care delivery systems in many industrialized nations is that desired population health metrics are often not achieved despite large expenditures in the health care delivery system.F...A fundamental paradox of the health care delivery systems in many industrialized nations is that desired population health metrics are often not achieved despite large expenditures in the health care delivery system.For example,the United States commits nearly 18%of its GDP to the health care delivery system,the largest amount of any nation,yet is 37th in achieving health or health care delivery metrics.This article addresses how general practice can be an important driver of population health in the Chinese health care delivery system through the application of quality improvement methods.The article shows examples of how the cause-and-effect diagram,the process map,and the plan,do,study,act(PDSA)cycle are important techniques to assist primary care practitioners for improving population health.展开更多
Objective:The Accountable Care Organization(ACO)model of health care delivery is based on new payment models for general practice to reward improved quality and decreased cost of care.Methods:Banner Health Network(BHN...Objective:The Accountable Care Organization(ACO)model of health care delivery is based on new payment models for general practice to reward improved quality and decreased cost of care.Methods:Banner Health Network(BHN)is one of the original CMS Pioneer ACO programs and implemented a comprehensive disease management program based on the collaborative care model.Key performance indicators for CMS reflected quality and cost of care.Results:BHN has demonstrated both improved quality and cost savings in the first two years of the pilot program.The disease management program based on the collaborative care model appears to have improved patient health outcomes based on quality improvement measures.In addition the program has reduced emergency department and hospital utilization,resulting in cost savings.Conclusions:The BHN quality improvement program is the platform for analyzing and improving on the BHN ACO model.This model appears to have excellent application to the China health care system that is also focused on prevention and improvement of chronic disease and cost-effectiveness.展开更多
BACKGROUND In 2016,the Chinese government issued the Healthy China 2030 plan,which also produced the initiative practice for health(IPFH)concept.However,people’s knowledge and awareness of the IPFH are unclear.AIM To...BACKGROUND In 2016,the Chinese government issued the Healthy China 2030 plan,which also produced the initiative practice for health(IPFH)concept.However,people’s knowledge and awareness of the IPFH are unclear.AIM To investigate awareness of IPFH in the Chinese population and explore the relevant influential factors.METHODS An internet-based self-designed questionnaire survey was used to collect respondents’demographic characteristics and awareness of health and the IPFH from March 26 to April 18,2020.IPFH consciousness was assessed by the scores for different related questions.The Student’s t test,the Chi-square test,and multiple logistic regression analysis were performed to analyze the differences and influencing factors.RESULTS A total of 2678 valid questionnaires were collected.Of the respondents,973(36.3%)had heard of the IPFH concept.In addition,89.5% of participants agreed with the view that the IPFH is beneficial to improving quality of life,and over half thought that a regular schedule,a reasonable diet,tobacco and alcohol control,a cheerful mood,specific life goals and plans,taking the initiative to accept health-related education and implement health knowledge,good interpersonal relationships,and regular physical examinations were closely related to the IPFH.The majority of respondents paid attention to their health and usually obtained health-related knowledge via social media and were also willing to promote the IPFH.Most of the participants underestimated the role of hospitals,family doctors,and health managers in promoting the IPFH.Age,monthly income,and medical-related work experience were the influencing factors for IPFH awareness.CONCLUSION The Chinese population has limited knowledge of the IPFH.People with strong IPFH awareness are older,earn more,and have medical-related work experience.展开更多
Human exposures to pesticides can occur in the workplace,in the household and through the ambient environment.While several articles have reviewed the impact of pesticide exposures on human respiratory health in occup...Human exposures to pesticides can occur in the workplace,in the household and through the ambient environment.While several articles have reviewed the impact of pesticide exposures on human respiratory health in occupational settings,to the best of our knowledge,this article is the first one to review published studies on the association between pesticide exposures and human respiratory health in the general populations.In this article,we critically reviewed evidences up to date studying the associations between non-occupational pesticide exposures and respiratory health in general populations.This article also highlighted questions arising from these studies,including our recent analyses using the data from the Canadian Health Measures Survey（CHMS）,for future research.We found few studies have addressed the impact of environmental pesticide exposures on respiratory health,especially on lung function,in general populations.In the studies using the data from CHMS Cycle 1,exposures to OP insecticides,pyrethroid insecticides,and the organochlorine pesticide DDT were associated with impaired lung function in the Canadian general population,but no significant associations were observed for the herbicide 2,4-D.Future research should focus on the potential age-specific and pesticide-specific effect on respiratory health in the general population,and repeated longitudinal study design is critical for assessing the temporal variations in pesticide exposures.Research findings from current studies of non-occupational pesticide exposures and their health impact in general population will help to improve the role of regulatory policies in mitigating pesticide-related public health problems,and thereafter providing greater benefit to the general population.展开更多
A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR...A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR),-GT, GPT and AKP, were employed in the present survey among occupationally vinyl chloride (VC) exposed workers and inhabitants living in VC polluted area in a polyvinyl chloride (PVC) factory. The results showed that the serum lysozyme (S-LZM) activities in Group 3 (adult inhabitants exposed to 0.20 mg/m3 VC for at least 8 years), Group 2 (workers exposed to 4.1 mg/m3for at least 7 years occupationally), Group 1 (workers exposed to 25.7 mg/m3 for at least 2 years) were significantly higher than control. G-banding CA analysis showed that the total chromosome breakage rates in both Groups 1 and 2 were higher, but no difference existed between Group 3 and control. Only Group 1 was observed having higher SCEs, CA level and lower TcTR than control. AKP levels in Groups 1 and 2 were higher than control,but noγ-GT and GPT differences were found among groups. The study also suggests that G-banding CA analysis is more sensitive than CA and SCEs展开更多
Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and wide...Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and widely used method of assessing muscular strength among people of all ages.While adult HGS norms have been published for many countries,no study has yet synthesized available data to produce international norms.The objective of this study was to generate international sex-and age-specific norms for absolute and body size-normalized HGS across the adult lifespan.Methods:Systematic searches were conducted in 6 databases/web search engines(MEDLINE,SPORTDiscus,Embase,Web of Science,CINAHL,and Google Scholar)up to December 1,2023.We included full-text peer-reviewed observational studies that reported normative HGS data for adults aged ≥20 years by sex and age.Pseudo data were generated using Monte Carlo simulation following harmonization for methodo-logical variation.Population-weighted Generalized Additive Models for Location,Scale,and Shape were used to develop sex-and age-specific norms for absolute HGS(kg)and HGS normalized by height(Ht,m)squared(i.e.,HGS/Ht^(2)in kg/m^(2)).Norms were tabulated as percentile values(5th to 95th)and visualized as smoothed percentile curves.Results:We included data from 100 unique observational studies representing 2,405,863 adults(51.9%female)aged 20 to 100+years from 69 countries and regions tested from the year 2000 onward.On average,absolute and normalized HGS values negligibly improved throughout early adulthood,peaked from age 3039 years(at 49.7 kg(males)and 29.7 kg(females)for absolute HGS or 16.3 kg/m^(2)(males)and 11.3 kg/m^(2)(females)for HGS/Ht^(2)),and declined afterwards.The age-related decline in HGS accelerated from middle to late adulthood and was slightly larger for males than for females during middle adulthood.Conclusion:This study provides the world’s largest and most geographically comprehensive international norms for adult HGS by sex and age.These norms have utility for global peer-comparisons,health screening,and surveillance.展开更多
To achieve awareness of the initiative practice for health concept in the Chinese population,traditional Chinese medicine(TCM)doctors should popularize TCM culture and knowledge among young people,people with a low le...To achieve awareness of the initiative practice for health concept in the Chinese population,traditional Chinese medicine(TCM)doctors should popularize TCM culture and knowledge among young people,people with a low level of education,in low-income populations,and in rural populations.展开更多
BACKGROUND Data on non-drug related risk-factors for gastrointestinal bleeding(GIB)in the general population are limited,especially for life-style factors,clinical measurements and laboratory parameters.AIM To identif...BACKGROUND Data on non-drug related risk-factors for gastrointestinal bleeding(GIB)in the general population are limited,especially for life-style factors,clinical measurements and laboratory parameters.AIM To identify and investigate non-drug risk factors for major GIB in the general population of Finland.METHODS We performed a retrospective cohort study using data from the FINRISK health examination surveys,which have been conducted every 5 years across Finland from 1987 to 2007.Participants were adults aged 25 years to 74 years,excluding those with a previous hospitalization for GIB.Follow-up from enrollment was performed through linkage to national electronic health registers and ended at an event of GIB that led to hospitalization/death,death due to any other cause,or after 10 years.Covariates included demographics,socioeconomic and lifestyle factors,clinical measurements,laboratory parameters and comorbidities.Variable selection was undertaken using Least Absolute Shrinkage and Selection Operator(LASSO)and factors associated with GIB were identified using Cox regression.RESULTS Among 33,508 participants,403(1.2%)experienced GIB[256 men(63.5%);mean age,56.0 years(standard deviation(SD)±12.1)]and 33105 who did not experience GIB[15768 men(47.6%);mean age,46.8(SD±13)years],within 10 years of follow-up.Factors associated with a significantly increased risk of GIB were baseline age[per 10-year increase;hazard ratio(HR)1.62,95%confidence interval(CI):1.42-1.86],unemployment(HR:1.70,95%CI:1.11-2.59),body mass index(BMI)(HR:1.15,95%CI:1.01-1.32),gamma-glutamyl transferase(GGT)(HR:1.05,95%CI:1.02-1.09),precursors of GIB(HR:1.90,95%CI:1.37-2.63),cancer(HR:1.47,95%CI:1.10-1.97),psychiatric disorders(HR:1.32,95%CI:1.01-1.71),heart failure(HR:1.46,95%CI:1.04-2.05),and liver disorders(HR:3.20,95%CI:2.06-4.97).Factors associated with a significantly decreased risk of GIB were systolic blood pressure(SBP)(HR:0.78,95%CI:0.64-0.96),6-10 cups of coffee a day(HR:0.67,95%CI:0.46-0.99),or>10 cups(HR:0.43,95%CI:0.23-0.81).CONCLUSION Our study confirms established risk-factors for GIB and identifies potential risk-factors not previously reported such as unemployment,BMI,GGT,SBP and coffee consumption.展开更多
Objective:Although evidence has already demonstrated that the performance of Health Deliv- ery System(HDS) varies widely across nations,relatively little is known about the factors that give rise to these variations a...Objective:Although evidence has already demonstrated that the performance of Health Deliv- ery System(HDS) varies widely across nations,relatively little is known about the factors that give rise to these variations and the key point to improve the performance besides adjusting system structure.By setup of HDS performance measurement system on the base of association of financial,social,and environmental characteristics,we construct system dynamic model of HDS to simulate the invention policies.Methods: Performance measures were collected from HDS in 31 regions of China and combined with secondary data sources.Multivariate,linear,nonlinear regression and factor analysis models were used to estimate associ- ations between system characteristics and the performance.Results:Performance varied significantly with the size,financial resources and organizational structure of HDS.Performance measurement system of health delivery system was developed to give the rank of all Chinese regions.Conclusion:Performance measurement system of HDS is the basic of HDS modeling by system dynamic.展开更多
After a review of recent developments in precision medicine, population health sciences and innovative clinical trial designs, and in health economics and policy, we show how innovations in health analytics can capita...After a review of recent developments in precision medicine, population health sciences and innovative clinical trial designs, and in health economics and policy, we show how innovations in health analytics can capitalize on the advances in biomedicine and health economics towards developing a data-driven and cost-effective 21<sup>st</sup> century health care system. In particular, we propose a mutually beneficial public-private partnership that combines individual responsibility with community solidarity in building this health care system.展开更多
The essential consideration is the cornerstone of a solid medical care system that provides outstanding health outcomes at a low cost. Medical therapy has evolved over the previous century from concentrating on random...The essential consideration is the cornerstone of a solid medical care system that provides outstanding health outcomes at a low cost. Medical therapy has evolved over the previous century from concentrating on random etiologies to lifestyle, race, and environmental factors. The aim behind these changes is to serve the public health requirements by delivering frequent and easy services based on the individual, couple, or family. Accurate evaluation of the magnitude by which primary health care contributes to the health care system is essential to the improvement of these contributions and determining next step considerations. The number one factor has been associated with greater access to medical care, better health outcomes, and reduced hospitalization and ER (emergency room) visits. The number one consideration may also help balance the adverse effects of poor financial situations on well-being. Therefore, we need more primary care doctors in the US. Research is also necessary to understand which essential consideration models provide acceptable health results.展开更多
The progressive aging of society is expected to lead to the development of effective integrated community-based care system considering the characteristics based on community environments. However, the COVID-19 pandem...The progressive aging of society is expected to lead to the development of effective integrated community-based care system considering the characteristics based on community environments. However, the COVID-19 pandemic has influenced population health worldwide. This study aimed to examine disparities in population health and health-related factors between rural and urban communities during the COVID-19 pandemic. A literature search was conducted using PubMed, Medline, and CINAHL for articles published up to September 2022 with the following search terms: community health, rural, urban, and COVID-19. A total of 105 articles were identified, of which three articles with a cross-sectional quantitative research design met the inclusion criteria. Two articles focused on mental health, and among them, one recognized a significant disparity between rural and urban areas. Four health-related factors in view of the COVID-19 pandemic in rural and urban areas were perceived, including knowledge, behavior, lifestyle, and social support. And, two factors: health-related knowledge and health-related behavior, were perceived as the significant disparities between rural and urban during the COVID-19 pandemic. The further efforts will be needed to pursue effective integrated community-based care system during and post-COVID-19, taking into account community environment at both community and individual levels.展开更多
Objective:This study investigates the geographical distribution of private hospitals in Australian capital cities in relation to the Index of Relative Socioeconomic Disadvantage.Methods:Using Geographic Information Sy...Objective:This study investigates the geographical distribution of private hospitals in Australian capital cities in relation to the Index of Relative Socioeconomic Disadvantage.Methods:Using Geographic Information System analysis,the study examined how private hospitals are distributed across different socioeconomic quartiles,providing a comprehensive visualisation of health care accessibility.Results:The results indicate an unequal distribution with a substantial concentration of private hospitals within the vicinity of communities classified in the highest socioeconomic classification.This raises significant concerns about health care equity,particularly in light of the increased strain on health care systems before,during and after the COVID‐19 pandemic.Conclusions:This study underscores the need for targeted policy interventions to enhance the resilience and accessibility of the private health care sector,specifically targeting disadvantaged communities.It suggests that comprehensive,geographically‐informed data is crucial for policymakers to make informed decisions that promote health equity in the postpandemic landscape.展开更多
Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of compara...Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of comparative studies on the current status of HP infection in high- and low-altitude. Therefore, this study aims to investigate the current status and differences in HP infection between the health check-up populations in the highland region and the plain area. Methods: This is a multicenter cross-sectional study, using convenience sampling method, which included the health check-up population of Ruoergai County People’s Hospital and the health check-up population of Deyang City People’s Hospital from January 2023 to December 2023, to carry out the questionnaire survey of HP-related factors, and to detect HP infection by a 13C-urea breath test. Results: The number of positives was 144 out of 260 health checkups in the plateau region, with a detection rate of 55.4%, which was significantly higher than that of 29.8% in the plains (P H. pylori infection-positive population, the health checkups in the plateau group had a lower education level, a higher proportion of overweight and obesity, a higher proportion of frequent smokers, a higher frequency of frequent eating out, and a lower proportion of abnormalities of uric acid, total cholesterol, LDL cholesterol, alanine aminotransferase, aspartate aminotransferase, and direct bilirubin but a higher proportion of abnormalities of total bilirubin. There was no statistically significant difference between the two groups in terms of age, gender, history of alcohol consumption, family history, urea, creatinine, and blood glucose. Conclusion: Preliminary results indicate that the rate of HP infection in the plateau population is significantly higher than that in the plains, and HP-related health education should be strengthened in the plateau region.展开更多
文摘National Population Health Data Center(NPHDC)is one of China's 20 national-level science data centers,jointly designated by the Ministry of Science and Technology and the Ministry of Finance.Operated by the Chinese Academy of Medical Sciences under the oversight of the National Health Commission,NPHDC adheres to national regulations including the Scientific Data Management Measures and the National Science and Technology Infrastructure Service Platform Management Measures,and is committed to collecting,integrating,managing,and sharing biomedical and health data through openaccess platform,fostering open sharing and engaging in international cooperation.
文摘The aim of the study is to identify sources of atmospheric pollutants and assess their impact on the health of Conakry’s population. Ten contaminant sources were identified. Sampling was conducted on suspended particles and gases. Physicochemical methods were used to determine pollutant levels. The results show that CO2 is the highest gaseous pollutant at the Dar es Salaam landfill (708 μg/m3), followed by CO (354 μg/m3). The highest content of volatile organic compounds (VOC) was observed at the Tombo thermal power plant (475 μg/m3). Nitrogen oxides and hydrocarbon pollutants (NOx and CnH2n+2) at each site were relatively stable, with levels between (100 - 150 μg/m3) and (450 μg/m3), respectively. Suspended particulates (PM10 and PM2.5) measured at various locations showed higher PM10 levels than PM2.5. In particular, the highest PM10 content was observed at the Sangoyah soap factory (410 μg/m3), followed by the Madina market (319 μg/m3) and the Dar-Es-Salam landfill (318 μg/m3). As indicated by the results, these contamination levels far exceed European and World Health Organization standards. This study highlights the need to adopt a strategy to reduce pollution levels at these critical points to protect the health of the city’s population.
基金the National Natural Science Foundation of China[grant numbers 42141019 and 42261144687]An Investigation Research Program between Ecological Environment and Human Health in Wuyi Mountain[grant number 20242120035]Natural Science Foundation of Hubei Province,China[grant number 2024AF-B115]。
文摘Against the backdrop of global warming,China has been facing increasingly frequent and severe extreme weather and climate events,with a prominent risk of compound extreme events induced by interactions among multiple climate drivers and/or hazards.The present study first reviews the definition and classification of compound extreme events in China.Then,it summarizes research progress on the evolutionary characteristics,formation mechanisms,and future projections of different types of compound extreme events.The potential risks and possible impact pathways of three specific event types—namely,continuous day–night hot extremes,temperature–humidity compound events,and high-temperature–ozone compound events—on the health of the Chinese population are then explored.Finally,a framework for assessing the hazard risk of compound extreme events is constructed,accompanied by response strategies based on carbon neutrality targets.Building on existing research achievements,five future research directions are proposed:(1)identifying the risk chains of compound events;(2)addressing the constraints of observational records and coupled model performances;(3)attributing and understanding the drivers of compound extreme events;(4)finding optimal pathways for carbon reduction and air quality improvement;and(5)promoting inter-disciplinary,multi-regional,and cross-sectoral collaboration.Strengthening research in these directions will deepen our understanding of compound extreme events and provide technological support for climate change adaptation and health risk responses in China.
文摘Chronic diseases,or NCDs(noncommunicable diseases),constitute a major global health challenge,causing millions of deaths and imposing substantial economic burdens annually.This paper introduces the Health Score,a comprehensive framework for assessing chronic disease risk by integrating diverse determinants of health,including social,economic,environmental,behavioral,treatment,culture,and nature factors.The Health Score,ranging from 0 to 850,quantifies indivi dual and population-level health risks while identifying protective factors through a structured methodology that supports targeted interventions at individual,corporate,and community scales.The paper highlights the rising prevalence of chronic diseases in the United States,projecting that nearly half of the population will be affected by 2030,alongside a global economic burden expected to reach trillions of dollars.Existing surveillance tools,such as the CDS(Chronic Disease Score)and CDIs(Chronic Disease Indicators),are examined for their roles in monitoring health disparities.The Health Score advances a holistic,proactive approach,emphasizing lifestyle modifications,equitable healthcare access,economic opportunities,social support,nature exposure,cu ltural awareness,and community engagement.By elucidating the complex interplay of health determinants,this framework equips stakeholders with actionable insights to implement effective prevention strategies,ultimately fostering healthier,more resi lient populations.
文摘Objective: To investigate and analyze the risk factors of lung cancer in the population of health checkups. Methods: A total of 500 cases of the health check-up population were selected for data study. Surveyed showed that 19 cases of lung cancer were grouped as the lung cancer group and the remaining 481 cases made up the control group, and the risk factors were analyzed. Results: Among men, there was a significant proportion of individuals aged 60-69 years old, and women aged 30-39 years old. Additionally, individuals aged 60 and above were at increased risk of developing lung cancer. The results of the multifactorial analysis were that the risk factors affecting the detection of lung cancer in healthy people were smoking history, family history of lung cancer, secondhand smoke, history of respiratory diseases, psychosomatic factors, living environment, and kitchen fumes. Conclusion: People over 60 years of age were prone to early lung cancer, followed by individuals aged 30-39 years. It is important to identify the risk factors of lung cancer to strengthen the screening of high-risk groups for early detection and treatment.
文摘Objective: To study the prevalence characteristics of pulmonary nodules and their influencing factors in the health check-up population. Methods: A total of 500 cases of health checkups were selected for the data study to analyze the detection and prevalence characteristics of pulmonary nodules. The influencing factors between the pulmonary nodules group and the no pulmonary nodules group were analyzed. Results: A total of 209 cases were detected, of which there were more males than females, and for female patients, the detection rate increased with age (P < 0.05). The distribution of gender, age, smoking, respiratory symptoms, and exposure to kitchen fumes between the two groups was compared (P < 0.05). The multifactorial analysis concluded that risk factors include, respiratory symptoms, older age, exposure to kitchen fumes, and smoking. In addition, patients who exercised more had a lower risk of developing lung nodules. Conclusion: The detection rate of pulmonary nodules was high in the health check-up population and the influencing factors analyzed involved the presence of respiratory symptoms, older age, kitchen fume exposure, and smoking, while the positive influencing factor was increased exercise.
文摘A fundamental paradox of the health care delivery systems in many industrialized nations is that desired population health metrics are often not achieved despite large expenditures in the health care delivery system.For example,the United States commits nearly 18%of its GDP to the health care delivery system,the largest amount of any nation,yet is 37th in achieving health or health care delivery metrics.This article addresses how general practice can be an important driver of population health in the Chinese health care delivery system through the application of quality improvement methods.The article shows examples of how the cause-and-effect diagram,the process map,and the plan,do,study,act(PDSA)cycle are important techniques to assist primary care practitioners for improving population health.
文摘Objective:The Accountable Care Organization(ACO)model of health care delivery is based on new payment models for general practice to reward improved quality and decreased cost of care.Methods:Banner Health Network(BHN)is one of the original CMS Pioneer ACO programs and implemented a comprehensive disease management program based on the collaborative care model.Key performance indicators for CMS reflected quality and cost of care.Results:BHN has demonstrated both improved quality and cost savings in the first two years of the pilot program.The disease management program based on the collaborative care model appears to have improved patient health outcomes based on quality improvement measures.In addition the program has reduced emergency department and hospital utilization,resulting in cost savings.Conclusions:The BHN quality improvement program is the platform for analyzing and improving on the BHN ACO model.This model appears to have excellent application to the China health care system that is also focused on prevention and improvement of chronic disease and cost-effectiveness.
基金Supported by the National Key R&D Program of China,No.2018YFC2000704.
文摘BACKGROUND In 2016,the Chinese government issued the Healthy China 2030 plan,which also produced the initiative practice for health(IPFH)concept.However,people’s knowledge and awareness of the IPFH are unclear.AIM To investigate awareness of IPFH in the Chinese population and explore the relevant influential factors.METHODS An internet-based self-designed questionnaire survey was used to collect respondents’demographic characteristics and awareness of health and the IPFH from March 26 to April 18,2020.IPFH consciousness was assessed by the scores for different related questions.The Student’s t test,the Chi-square test,and multiple logistic regression analysis were performed to analyze the differences and influencing factors.RESULTS A total of 2678 valid questionnaires were collected.Of the respondents,973(36.3%)had heard of the IPFH concept.In addition,89.5% of participants agreed with the view that the IPFH is beneficial to improving quality of life,and over half thought that a regular schedule,a reasonable diet,tobacco and alcohol control,a cheerful mood,specific life goals and plans,taking the initiative to accept health-related education and implement health knowledge,good interpersonal relationships,and regular physical examinations were closely related to the IPFH.The majority of respondents paid attention to their health and usually obtained health-related knowledge via social media and were also willing to promote the IPFH.Most of the participants underestimated the role of hospitals,family doctors,and health managers in promoting the IPFH.Age,monthly income,and medical-related work experience were the influencing factors for IPFH awareness.CONCLUSION The Chinese population has limited knowledge of the IPFH.People with strong IPFH awareness are older,earn more,and have medical-related work experience.
文摘Human exposures to pesticides can occur in the workplace,in the household and through the ambient environment.While several articles have reviewed the impact of pesticide exposures on human respiratory health in occupational settings,to the best of our knowledge,this article is the first one to review published studies on the association between pesticide exposures and human respiratory health in the general populations.In this article,we critically reviewed evidences up to date studying the associations between non-occupational pesticide exposures and respiratory health in general populations.This article also highlighted questions arising from these studies,including our recent analyses using the data from the Canadian Health Measures Survey（CHMS）,for future research.We found few studies have addressed the impact of environmental pesticide exposures on respiratory health,especially on lung function,in general populations.In the studies using the data from CHMS Cycle 1,exposures to OP insecticides,pyrethroid insecticides,and the organochlorine pesticide DDT were associated with impaired lung function in the Canadian general population,but no significant associations were observed for the herbicide 2,4-D.Future research should focus on the potential age-specific and pesticide-specific effect on respiratory health in the general population,and repeated longitudinal study design is critical for assessing the temporal variations in pesticide exposures.Research findings from current studies of non-occupational pesticide exposures and their health impact in general population will help to improve the role of regulatory policies in mitigating pesticide-related public health problems,and thereafter providing greater benefit to the general population.
文摘A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR),-GT, GPT and AKP, were employed in the present survey among occupationally vinyl chloride (VC) exposed workers and inhabitants living in VC polluted area in a polyvinyl chloride (PVC) factory. The results showed that the serum lysozyme (S-LZM) activities in Group 3 (adult inhabitants exposed to 0.20 mg/m3 VC for at least 8 years), Group 2 (workers exposed to 4.1 mg/m3for at least 7 years occupationally), Group 1 (workers exposed to 25.7 mg/m3 for at least 2 years) were significantly higher than control. G-banding CA analysis showed that the total chromosome breakage rates in both Groups 1 and 2 were higher, but no difference existed between Group 3 and control. Only Group 1 was observed having higher SCEs, CA level and lower TcTR than control. AKP levels in Groups 1 and 2 were higher than control,but noγ-GT and GPT differences were found among groups. The study also suggests that G-banding CA analysis is more sensitive than CA and SCEs
基金supported by European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement(No.101028929)BJFis supported by National Heart Foundation of Australia Postdoc-toral Fellowship(No.106588)+1 种基金BG is supported by Australian Government Research Training Program ScholarshipDPLis supported by Clive Kearon Award,McMaster University.Additional funding information can be found in Supplemen-tary Funding.
文摘Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and widely used method of assessing muscular strength among people of all ages.While adult HGS norms have been published for many countries,no study has yet synthesized available data to produce international norms.The objective of this study was to generate international sex-and age-specific norms for absolute and body size-normalized HGS across the adult lifespan.Methods:Systematic searches were conducted in 6 databases/web search engines(MEDLINE,SPORTDiscus,Embase,Web of Science,CINAHL,and Google Scholar)up to December 1,2023.We included full-text peer-reviewed observational studies that reported normative HGS data for adults aged ≥20 years by sex and age.Pseudo data were generated using Monte Carlo simulation following harmonization for methodo-logical variation.Population-weighted Generalized Additive Models for Location,Scale,and Shape were used to develop sex-and age-specific norms for absolute HGS(kg)and HGS normalized by height(Ht,m)squared(i.e.,HGS/Ht^(2)in kg/m^(2)).Norms were tabulated as percentile values(5th to 95th)and visualized as smoothed percentile curves.Results:We included data from 100 unique observational studies representing 2,405,863 adults(51.9%female)aged 20 to 100+years from 69 countries and regions tested from the year 2000 onward.On average,absolute and normalized HGS values negligibly improved throughout early adulthood,peaked from age 3039 years(at 49.7 kg(males)and 29.7 kg(females)for absolute HGS or 16.3 kg/m^(2)(males)and 11.3 kg/m^(2)(females)for HGS/Ht^(2)),and declined afterwards.The age-related decline in HGS accelerated from middle to late adulthood and was slightly larger for males than for females during middle adulthood.Conclusion:This study provides the world’s largest and most geographically comprehensive international norms for adult HGS by sex and age.These norms have utility for global peer-comparisons,health screening,and surveillance.
基金Supported by the 2021 Shanghai University of Traditional Chinese Medicine Postgraduate Innovation and Entrepreneurship Training Project,No.Y2021070。
文摘To achieve awareness of the initiative practice for health concept in the Chinese population,traditional Chinese medicine(TCM)doctors should popularize TCM culture and knowledge among young people,people with a low level of education,in low-income populations,and in rural populations.
文摘BACKGROUND Data on non-drug related risk-factors for gastrointestinal bleeding(GIB)in the general population are limited,especially for life-style factors,clinical measurements and laboratory parameters.AIM To identify and investigate non-drug risk factors for major GIB in the general population of Finland.METHODS We performed a retrospective cohort study using data from the FINRISK health examination surveys,which have been conducted every 5 years across Finland from 1987 to 2007.Participants were adults aged 25 years to 74 years,excluding those with a previous hospitalization for GIB.Follow-up from enrollment was performed through linkage to national electronic health registers and ended at an event of GIB that led to hospitalization/death,death due to any other cause,or after 10 years.Covariates included demographics,socioeconomic and lifestyle factors,clinical measurements,laboratory parameters and comorbidities.Variable selection was undertaken using Least Absolute Shrinkage and Selection Operator(LASSO)and factors associated with GIB were identified using Cox regression.RESULTS Among 33,508 participants,403(1.2%)experienced GIB[256 men(63.5%);mean age,56.0 years(standard deviation(SD)±12.1)]and 33105 who did not experience GIB[15768 men(47.6%);mean age,46.8(SD±13)years],within 10 years of follow-up.Factors associated with a significantly increased risk of GIB were baseline age[per 10-year increase;hazard ratio(HR)1.62,95%confidence interval(CI):1.42-1.86],unemployment(HR:1.70,95%CI:1.11-2.59),body mass index(BMI)(HR:1.15,95%CI:1.01-1.32),gamma-glutamyl transferase(GGT)(HR:1.05,95%CI:1.02-1.09),precursors of GIB(HR:1.90,95%CI:1.37-2.63),cancer(HR:1.47,95%CI:1.10-1.97),psychiatric disorders(HR:1.32,95%CI:1.01-1.71),heart failure(HR:1.46,95%CI:1.04-2.05),and liver disorders(HR:3.20,95%CI:2.06-4.97).Factors associated with a significantly decreased risk of GIB were systolic blood pressure(SBP)(HR:0.78,95%CI:0.64-0.96),6-10 cups of coffee a day(HR:0.67,95%CI:0.46-0.99),or>10 cups(HR:0.43,95%CI:0.23-0.81).CONCLUSION Our study confirms established risk-factors for GIB and identifies potential risk-factors not previously reported such as unemployment,BMI,GGT,SBP and coffee consumption.
文摘Objective:Although evidence has already demonstrated that the performance of Health Deliv- ery System(HDS) varies widely across nations,relatively little is known about the factors that give rise to these variations and the key point to improve the performance besides adjusting system structure.By setup of HDS performance measurement system on the base of association of financial,social,and environmental characteristics,we construct system dynamic model of HDS to simulate the invention policies.Methods: Performance measures were collected from HDS in 31 regions of China and combined with secondary data sources.Multivariate,linear,nonlinear regression and factor analysis models were used to estimate associ- ations between system characteristics and the performance.Results:Performance varied significantly with the size,financial resources and organizational structure of HDS.Performance measurement system of health delivery system was developed to give the rank of all Chinese regions.Conclusion:Performance measurement system of HDS is the basic of HDS modeling by system dynamic.
文摘After a review of recent developments in precision medicine, population health sciences and innovative clinical trial designs, and in health economics and policy, we show how innovations in health analytics can capitalize on the advances in biomedicine and health economics towards developing a data-driven and cost-effective 21<sup>st</sup> century health care system. In particular, we propose a mutually beneficial public-private partnership that combines individual responsibility with community solidarity in building this health care system.
文摘The essential consideration is the cornerstone of a solid medical care system that provides outstanding health outcomes at a low cost. Medical therapy has evolved over the previous century from concentrating on random etiologies to lifestyle, race, and environmental factors. The aim behind these changes is to serve the public health requirements by delivering frequent and easy services based on the individual, couple, or family. Accurate evaluation of the magnitude by which primary health care contributes to the health care system is essential to the improvement of these contributions and determining next step considerations. The number one factor has been associated with greater access to medical care, better health outcomes, and reduced hospitalization and ER (emergency room) visits. The number one consideration may also help balance the adverse effects of poor financial situations on well-being. Therefore, we need more primary care doctors in the US. Research is also necessary to understand which essential consideration models provide acceptable health results.
文摘The progressive aging of society is expected to lead to the development of effective integrated community-based care system considering the characteristics based on community environments. However, the COVID-19 pandemic has influenced population health worldwide. This study aimed to examine disparities in population health and health-related factors between rural and urban communities during the COVID-19 pandemic. A literature search was conducted using PubMed, Medline, and CINAHL for articles published up to September 2022 with the following search terms: community health, rural, urban, and COVID-19. A total of 105 articles were identified, of which three articles with a cross-sectional quantitative research design met the inclusion criteria. Two articles focused on mental health, and among them, one recognized a significant disparity between rural and urban areas. Four health-related factors in view of the COVID-19 pandemic in rural and urban areas were perceived, including knowledge, behavior, lifestyle, and social support. And, two factors: health-related knowledge and health-related behavior, were perceived as the significant disparities between rural and urban during the COVID-19 pandemic. The further efforts will be needed to pursue effective integrated community-based care system during and post-COVID-19, taking into account community environment at both community and individual levels.
文摘Objective:This study investigates the geographical distribution of private hospitals in Australian capital cities in relation to the Index of Relative Socioeconomic Disadvantage.Methods:Using Geographic Information System analysis,the study examined how private hospitals are distributed across different socioeconomic quartiles,providing a comprehensive visualisation of health care accessibility.Results:The results indicate an unequal distribution with a substantial concentration of private hospitals within the vicinity of communities classified in the highest socioeconomic classification.This raises significant concerns about health care equity,particularly in light of the increased strain on health care systems before,during and after the COVID‐19 pandemic.Conclusions:This study underscores the need for targeted policy interventions to enhance the resilience and accessibility of the private health care sector,specifically targeting disadvantaged communities.It suggests that comprehensive,geographically‐informed data is crucial for policymakers to make informed decisions that promote health equity in the postpandemic landscape.
文摘Background: China has a high prevalence of HP infection, and the rate of HP infection in highland populations is higher than the average rate of HP infection in natural populations. However, there is a lack of comparative studies on the current status of HP infection in high- and low-altitude. Therefore, this study aims to investigate the current status and differences in HP infection between the health check-up populations in the highland region and the plain area. Methods: This is a multicenter cross-sectional study, using convenience sampling method, which included the health check-up population of Ruoergai County People’s Hospital and the health check-up population of Deyang City People’s Hospital from January 2023 to December 2023, to carry out the questionnaire survey of HP-related factors, and to detect HP infection by a 13C-urea breath test. Results: The number of positives was 144 out of 260 health checkups in the plateau region, with a detection rate of 55.4%, which was significantly higher than that of 29.8% in the plains (P H. pylori infection-positive population, the health checkups in the plateau group had a lower education level, a higher proportion of overweight and obesity, a higher proportion of frequent smokers, a higher frequency of frequent eating out, and a lower proportion of abnormalities of uric acid, total cholesterol, LDL cholesterol, alanine aminotransferase, aspartate aminotransferase, and direct bilirubin but a higher proportion of abnormalities of total bilirubin. There was no statistically significant difference between the two groups in terms of age, gender, history of alcohol consumption, family history, urea, creatinine, and blood glucose. Conclusion: Preliminary results indicate that the rate of HP infection in the plateau population is significantly higher than that in the plains, and HP-related health education should be strengthened in the plateau region.
