BACKGROUND: Venous thromboembolism(VTE), including both deep vein thrombosis(DVT) and pulmonary embolism(PE), is a common, lethal disorder that affects hospitalized and nonhospitalized patients. This study aimed to re...BACKGROUND: Venous thromboembolism(VTE), including both deep vein thrombosis(DVT) and pulmonary embolism(PE), is a common, lethal disorder that affects hospitalized and nonhospitalized patients. This study aimed to review the progress in the research into VTE.DATA SOURCES: We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE.RESULTS: The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities.CONCLUSION: VTE has many risk factors, but genetic factors play an important role.展开更多
文摘BACKGROUND: Venous thromboembolism(VTE), including both deep vein thrombosis(DVT) and pulmonary embolism(PE), is a common, lethal disorder that affects hospitalized and nonhospitalized patients. This study aimed to review the progress in the research into VTE.DATA SOURCES: We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE.RESULTS: The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities.CONCLUSION: VTE has many risk factors, but genetic factors play an important role.
