Polydopamine(PD)coating,one of the simplest and most versatile surface functionalization method faces challenges in terms of stability and reactivity.In this study,we propose an in situ dynamic reassembly approach to ...Polydopamine(PD)coating,one of the simplest and most versatile surface functionalization method faces challenges in terms of stability and reactivity.In this study,we propose an in situ dynamic reassembly approach to address these challenges.By immersing a pre-deposited PD coating in a strong alkaline solution containing poly(allylamine)hydrochloride(PAH),the dissociated PD oligomers undergo covalent crosslinking in situ,leading to the formation of a reconstructed PDPA coating enriched with stable amino groups through thorough crosslinking.The PDPA coating demonstrates superior chemical and mechanical stability compared to PD,while enhancing multifunctional properties and offering improved surface functional modification potential.The PDPA coating holds promise in materials science,biomedical engineering,and nanotechnology,enabling versatile surface modification and functionalization in extreme conditions.展开更多
基金supported by the National Natural Science Foundation of China(Nos.82301156,32371377,and 52203131)Leading Talent Project of Guangzhou Development District(No.2020L013)+1 种基金the Zhejiang Provincial Natural Science Foundation of China(No.LTGY23H140001)the Fundamental Research Funds for Wenzhou Medical University(No.KYYW202208)。
文摘Polydopamine(PD)coating,one of the simplest and most versatile surface functionalization method faces challenges in terms of stability and reactivity.In this study,we propose an in situ dynamic reassembly approach to address these challenges.By immersing a pre-deposited PD coating in a strong alkaline solution containing poly(allylamine)hydrochloride(PAH),the dissociated PD oligomers undergo covalent crosslinking in situ,leading to the formation of a reconstructed PDPA coating enriched with stable amino groups through thorough crosslinking.The PDPA coating demonstrates superior chemical and mechanical stability compared to PD,while enhancing multifunctional properties and offering improved surface functional modification potential.The PDPA coating holds promise in materials science,biomedical engineering,and nanotechnology,enabling versatile surface modification and functionalization in extreme conditions.
