Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to thei...Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to their small gyromagnetic ratios.A promising approach to achieving high nuclear spin polarization is transferring the polarization of electrons to nuclear spins.The nitrogen-vacancy(NV)center in diamond has emerged as a highly effective medium for this purpose,and various hyperpolarization protocols have been developed.Among these,the pulsed polarization(PulsePol)method has been extensively studied due to its robustness against static energy shifts of the electron spin.In this work,we present a novel polarization protocol and uncover a family of magic sequences for hyperpolarizing nuclear spins,with PulsePol emerging as a special case of our general approach.Notably,we demonstrate that some of these magic sequences exhibit significantly greater robustness compared to the PulsePol protocol in the presence of finite half𝜋pulse duration of the protocol,Rabi and detuning errors.This enhanced robustness positions our protocol as a more suitable candidate for hyper-polarizing nuclear spins species with large gyromagnetic ratios and also ensures better compatibility with high-efficiency readout techniques at high magnetic fields.Additionally,the generality of our protocol allows for its direct application to other solid-state quantum systems beyond the NV center.展开更多
A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effe...A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effect.At room temperature,a stable dual-wavelength laser and a multi-output port laser which can simultaneously emit single-wavelength lasing and dual-wavelength lasing are obtained.The signal-to-noise ratios(SNRs)for single-wavelength outputs were 54.70 dB and 57.10 dB,with power fluctuations less than 0.038 mW and 0.029 mW,respectively.For dual-wavelength lasing,the SNRs were 59.63 dB and 59.25 dB,with power fluctuations less than 0.018 mW and 0.008 mW,respectively.The center wavelength drift was less than 0.006 nm for both single-wavelength and dual-wavelength outputs.展开更多
Autonomous navigation is a key technology for unmanned motion platforms to perform their tasks smoothly.The current approaches for daytime polarization navigation have been extensively researched.However,the polarizat...Autonomous navigation is a key technology for unmanned motion platforms to perform their tasks smoothly.The current approaches for daytime polarization navigation have been extensively researched.However,the polarization light intensity is the fundamental information within the polarization image,and the light intensity at night is 6-8 orders of magnitude lower than that during the day,which increase the noise and the loss of local polarization information due to occlusion,resulting in a significant decrease in the polarization orientation accuracy.Aimed at the problem,a bio-inspired model is introduced to denoise and enhance weak nighttime polarization patterns.Further,to address the issue of outlier interference in the occluded environment during practical application,a fast-fitting method of the solar meridian based on the anti-symmetric distribution of the polarization angle adjusted by Proportional and Differential(PD)control is proposed.The experimental results show that the method proposed in this paper achieves a dynamic orientation error Root Mean Square Error(RMSE)of 0.7°in the weak polarization mode at night and in the presence of local occlusion.The proposed method has strong robustness under weak polarization occlusion at night,and the orientation accuracy is improved by 97%and 80%in comparison to the least squares method,which provides a new method for polarization navigation at night.This effectively improves the robustness and environmental applicability of the bionic polarization compass for nighttime applications.展开更多
Diabetes mellitus is an escalating global health issue,with 463 million adults affected in 2019.Without intervention,this number is projected to increase to 578 million by 2030 and 700 million by 2045[1].Diabetic woun...Diabetes mellitus is an escalating global health issue,with 463 million adults affected in 2019.Without intervention,this number is projected to increase to 578 million by 2030 and 700 million by 2045[1].Diabetic wound,a significant complication,is characterized by delayed healing,high disability rates,and elevated mortality[2].The challenges of wound healing in diabetic patients,compounded by their high morbidity and mortality rates,have drawn growing attention in biomedical research.展开更多
With the acceleration of global aging,the incidence of retinal vein occlusion(RVO)has risen markedly.Its pathogenic mechanisms are closely linked to iron dyshomeostasis and microglial polarization and agerelated degen...With the acceleration of global aging,the incidence of retinal vein occlusion(RVO)has risen markedly.Its pathogenic mechanisms are closely linked to iron dyshomeostasis and microglial polarization and agerelated degenerative changes in retinal microvessels.We systematically summarize the regulatory mechanisms of ferroptosis-an iron-dependent,lipid peroxidation-driven form of cell death,and elucidate the central pathway by which iron overload exacerbates retinal injury through the synergy of hypoxia-reoxygenation(H/R).Specifically,iron metabolic imbalance catalyzes the production of reactive oxygen species(ROS)via the Fenton reaction,which drives the polarization of microglia toward the proinflammatory M1 phenotype and activates the acyl-CoA synthetase long-chain family member 4(ACSL4)-mediated lipid peroxidation cascade.This review proposes novel insights for combinatorial therapeutic strategies targeting key ferroptotic pathways(e.g.,the SLC7A11/GPX4 axis)and modulating microglial polarization,while also addressing the translational challenges associated with iron chelators(deferoxamine),lipid peroxidation inhibitors(liproxstatin-1),and targeted delivery systems for RVO.展开更多
In complex media scattering,multiple scattering severely degrades the optical wavefront and results in blurred images,while the spectral distortion caused by the scattering effect leads to severe color distortion.Achi...In complex media scattering,multiple scattering severely degrades the optical wavefront and results in blurred images,while the spectral distortion caused by the scattering effect leads to severe color distortion.Achieving color high-resolution imaging through scattering media remains a significant challenge.Here,we propose a broadband,polarization-based method for color high-resolution imaging through scattering media.This approach enables high-resolution reconstruction by effectively separating the speckle illumination pattern from the mixed-scattering field information,leveraging polarization common-mode characteristics.Concurrently,it incorporates chromatic balance compensation to correct spectral aliasing in the scattered light field,enabling color high-resolution imaging through complex scattering media.To further optimize color distortion caused by scattering,a compensation strategy combining color constancy and white balance theory is adopted.Experimental results demonstrate that the proposed method significantly enhances both spatial resolution and color fidelity across various scattering conditions and target materials,showcasing strong adaptability and robustness.This approach provides an effective solution for achieving high-resolution color optical imaging in complex scattering environments.展开更多
Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric ...Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric loss.However,the relationship between chain structure and dielectric properties is not yet clear.Ketal-containing crosslinked polyurethane elastomers were prepared using cyclic ketal diol as a chain extender.The effect of the soft segment length on the dielectric properties and energy storage was investigated.The cause of the change in the dipolar polarization with the soft segment length was analyzed.As the soft segment length increased,the hard-soft hydrogen bonding decreased,whereas the hard-hard hydrogen bonding increased.Under the action of an electric field,the polar bonds in the ketal-containing polyurethane elastomer overcome the hydrogen bonding between hard-soft segments to produce polarization;meanwhile,they also experience crankshaft motions to generate polarization.The former has a relatively high relaxation activation energy of approximately 10-20 k J·mol^(-1),resulting in a large dielectric loss.The latter has a relatively low relaxation activation energy,approximately 0.7-1.7 kJ·mol^(-1),leading to low dielectric loss.As a result,the dielectric constant showed a decreasing trend,and the dielectric loss gradually decreased.This study provides a theoretical foundation for improving the dielectric properties of polyurethane elastomers.展开更多
Ceramic cells promise ideal energy conversion and storage devices,making the development of efficient and robust air electrodes crucial for their application.In this study,a Ba_(0.4)Sr_(0.5)Cs_(0.1)Co_(0.7)Fe_(0.2)Nb_...Ceramic cells promise ideal energy conversion and storage devices,making the development of efficient and robust air electrodes crucial for their application.In this study,a Ba_(0.4)Sr_(0.5)Cs_(0.1)Co_(0.7)Fe_(0.2)Nb_(0.1)O_(3−δ)(BSCCFN)air electrode,based on Ba_(0.5)Sr_(0.5)Co_(0.8)Fe_(0.2)O_(3−δ)(BSCF),is designed using a perovskite A-B-site ionic Lewis acid strength(ISA)polarization distribution strategy and is successfully applied in both oxygen-ion conducting solid oxide fuel cells(O-SOFCs)and proton-conducting reversible protonic ceramic cells(R-PCCs).When BSCCFN is used as the air electrode in O-SOFCs,a peak power density(PPD)of 1.45 W cm^(−2)is achieved at 650°C,whereas in R-PCCs,a PPD of 1.13 W cm^(−2)and a current density of−1.8 A cm^(−2)at 1.3 V are achieved at the same temperature and show stable reversibility over 100 h.Experimental measurements and theoretical calculations demonstrate that low-ISA Cs+doping accelerates the reaction kinetics of both oxygen ions and protons,while high-ISA Nb^(5+)doping enhances electrode stability.The synergistic effect of Cs^(+)and Nb^(5+)co-doping in the BSCCFN electrode lies in the ISA polarization distribution,which weakens the Co/Fe–O bond covalency,thereby promoting oxygen vacancy formation and facilitating the conduction of oxygen ions and protons.展开更多
Three-quasiparticle K-isomeric states in odd-mass N=106 isotones within the A~180 mass region were systematically investigated using configuration-constrained potential energy surface calculations.The calculations suc...Three-quasiparticle K-isomeric states in odd-mass N=106 isotones within the A~180 mass region were systematically investigated using configuration-constrained potential energy surface calculations.The calculations succes sfully reproduced the excitation energies and deformations of the known high-K isomers in nuclei from 175Tm to 181Re.For the nuclei closer to the Z=82 shell closure(^(183)Ir,^(185)Au,and^(187)Tl),predictions of the configurations of the observed and yet-to-be-observed isomers are provided.The results reveal strong shape polarization,where the three-quasiparticle states are driven to larger deformations compared to the often shape-soft or spherical ground states.A particularly rich spectrum of shape coexistence is predicted in^(187)Tl,where several high-K three-quasiparticle configurations with distinct prolate,oblate,and triaxial shapes are found to coexist at similar excitation energies.Notably,the oblate-deformed K^(π)=29/2^(+)configuration at E_(x)=1839 keV was proposed to be responsible for a long-lived isomer.This study provides a comprehensive picture of shape evolution and coexistence in high-K multi-quasiparticle states,offering valuable insights for future experimental studies.展开更多
Objective:To investigate the effect of pectic polysaccharides isolated from Rauvolfia verticillata on ulcerative colitis and its underlying mechanisms.Methods:Pectic polysaccharides were characterized using high-perfo...Objective:To investigate the effect of pectic polysaccharides isolated from Rauvolfia verticillata on ulcerative colitis and its underlying mechanisms.Methods:Pectic polysaccharides were characterized using high-performance liquid chromatography with 1-phenyl-3-methyl-5-pyrazolone pre-column derivatization,phenol-sulfuric acid assay,and gel permeation chromatography.HT-29 cells were stimulated with lipopolysaccharide and then treated with pectic polysaccharides;conditioned medium was applied to THP-1-derived macrophages to assess cell viability and polarization,while tight junction protein expression was analyzed in HT-29 cells.Furthermore,a mouse model of dextran sulfate sodium-induced colitis was treated with oral pectic polysaccharides or NOS2 overexpression.Body weight,disease activity index,colon length,histopathology,and the protein expression related to the JAK2/STAT3-NOS2 signaling were evaluated.Results:The pectic polysaccharide was characterized as an acidic pectic polysaccharide,primarily composed of galacturonic acid and various neutral sugars,with a narrow molecular weight distribution and high purity.Pectic polysaccharides significantly enhanced THP-1 macrophage viability,promoted M1 to M2 polarization,and upregulated the expression of epithelial tight junction proteins.In addition,pectic polysaccharide treatment attenuated body weight loss,lowered disease activity index scores and improved colon histology in mice with dextran sulfate sodium-induced colitis.It also reduced JAK2/STAT3 phosphorylation and NOS2 expression,and increased the expression of tight junction proteins(ZO-1,occludin,and claudin-1).Conclusions:Pectic polysaccharides attenuate ulcerative colitis by increasing M2-related macrophage markers,inhibiting the JAK2/STAT3-NOS2 signaling,and enhancing epithelial barrier-related protein expression.These findings support pectic polysaccharides as a natural candidate for the treatment of ulcerative colitis.展开更多
Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordina...Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordinary(L-X)modes.The role of AKR in magnetosphere−ionosphere−atmosphere coupling depends sensitively on its wave mode.While previous studies have primarily focused on the dominant R-X mode,we present the first systematic identification of all three modes using a practical polarization analysis method based on Arase satellite observations.This method employs a spin-axis-relative Ratio:when the satellite's spin axis aligns with the background magnetic field,a positive(negative)Ratio indicates the right-handed(left-handed)polarization,with reversal under anti-parallel conditions.Combined polarization-frequency analysis reveals that R-X,L-O,and L-X modes can exist in both dayside and nightside regions,with power spectral densities up to 10^(-6)mV^(2)m^(-2)Hz^(-1).This study resolves long-standing ambiguities in AKR mode classification and has implications for understanding AKR-induced electron dynamics.展开更多
Three-dimensional(3D)-printed hydrogel scaffolds are widely used in spinal cord injury repair,with gelatin methacrylate being particularly favored owing to its excellent biocompatibility.However,traditional scaffolds ...Three-dimensional(3D)-printed hydrogel scaffolds are widely used in spinal cord injury repair,with gelatin methacrylate being particularly favored owing to its excellent biocompatibility.However,traditional scaffolds have a small contact area with tissues and lack the ability to regulate the inflammatory microenvironment.Therefore,there is a need to develop smart scaffolds with drug delivery and immune regulation functions.In this study,a 3D-printed gelatin methacrylate scaffold was developed to deliver interferon regulatory factor 4 in a targeted and sustained manner.The scaffold showed good mechanical properties,biocompatibility,and sustained interferon regulatory factor 4 release.The sustained-release interferon regulatory factor 4 competitively bound to myeloid differentiation factor 88 to inhibit the pro-inflammatory effects of interferon regulatory factor 5,and activated the signal transducer and activator of transcription 6 pathway to promote M2 macrophage polarization,thereby facilitating neural regeneration and recovery of spinal cord function.This indicates that the constructed interferon regulatory factor 4-loaded 3D-printed methyl acrylate-modified gelatin scaffold can regulate macrophage polarization through the interferon regulatory factor 4/5 axis,improve the inflammatory microenvironment after spinal cord injury,and thus provide a new target for promoting neural regeneration.展开更多
Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease indu...Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.However,the effect of GLP-1 on intrinsic synuclein malfunction remains unclear.In this study,we investigated the effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism in SncaA53T transgenic mice and explored the underlying mechanisms.Our data showed that Lactococcus lactis MG1363-pMG36e-GLP-1 inhibited dopaminergic neuronal death,reduced pathological aggregation ofα-synuclein,and decreased movement disorders in SncaA53T transgenic mice.Furthermore,Lactococcus lactis MG1363-pMG36e-GLP-1 downregulated lipopolysaccharide-related inflammation,reduced cerebral activation of microglia and astrocytes,and promoted cell survival via the GLP-1 receptor/PI3K/Akt pathway in the substantia nigra.Additionally,Lactococcus lactis MG1363-pMG36e-GLP-1 decreased serum levels of pro-inflammatory molecules including lipopolysaccharide,lipopolysaccharide binding protein,interleukin-1β,and interleukin-6.Gut histopathology and western blotting further revealed that Lactococcus lactis MG1363-pMG36e-GLP-1 increased the expression of gut integrity-related proteins and reduced lipopolysaccharide-related inflammation by reversing gut dysbiosis in SncaA53T transgenic mice.Our findings showed that the beneficial effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism traits in SncaA53T transgenic mice is mediated by microglial polarization and the reversal of dysbiosis.Collectively,our findings suggest that Lactococcus lactis MG1363-pMG36e-GLP-1 is a promising therapeutic agent for the treatment of Parkinson’s disease.展开更多
Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modu...Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.展开更多
The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.How...The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.However,conventional polarization detection systems are often bulky and complex,limiting their poten⁃tial for broader applications.To address the challenges of miniaturization,integrated polarization detectors have been extensively explored in recent years,achieving significant advancements in performance and functionality.In this review,we focus mainly on integrated polarization detectors with innovative features,including infinitely high polarization discrimination,ultrahigh sensitivity to polarization state change,full Stokes parameters measure⁃ment,and simultaneous perception of polarization and other key properties of light.Lastly,we discuss the oppor⁃tunities and challenges for the future development of integrated polarization photodetectors.展开更多
To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed,...To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed, based on the principle of bidirectional reflectance distribution function(BRDF), to obtain spectral reflection intensities of coatings at full spatial angles, and use polarization images to calculate the refractive index by the Fresnel equation. The index is then coupled into TorranceSparrow model to simulate the spectral scattering intensity to mutually verify the experimental results. The spectral scattering characteristics of standard camouflage patterns are then revealed and pinpoint the signature band and the angle of reflecting sensitivity.展开更多
Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we ...Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we propose a magnetized plasma platform for dynamic THz polarization control by exploiting the intrinsic birefringence between extraordinary and ordinary modes.We identify a strong-magnetization,zero-group-velocity-mismatch regime where the two modes share matched group velocities while retaining finite phase birefringence,enabling robust,phase-stable spin angular momentum control.By tuning the plasma length and magnetic field,we realize programmable phase retardation and demonstrate universal single-qubit gates through parameterized unitary operations.Full-wave particle-in-cell simulations validate high-fidelity polarization transformations across the Poincarésphere and demonstrate the potential for generating structured vector beams under spatially varying magnetic fields.The platform offers ultrafast response,resilience to extreme THz intensities,and in situ tunability,positioning magnetized plasmas as a versatile and damage-resilient medium for next-generation THz polarization control and structured-wave applications.展开更多
As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with othe...As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with other fundamental properties of light,such as intensity,wavelength and phase,polarization has a shorter application history in biomedicine,because of the requirement for both advanced polarization optical components and computational approaches,which can be achieved nowadays with the fast theoretical and hardware development.展开更多
BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes co...BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes could have significant prognostic implications,and manipulating this polarization may offer a novel approach to controlling colorectal neoplasms.AIM To evaluate the infiltration rates of M1 and M2 macrophages in colorectal neoplasia,specifically comparing cases with and without metalloproteinase mutations.Additionally,it sought to explore potential prognostic factors as-sociated with the disease.展开更多
Spontaneous polarization due to symmetry breaking in the transition metal ditellurides(MTe_(2))family exhibits intriguing sliding ferroelectricity.Although theoretical predictions of MTe_(2)ferroelectric metals with n...Spontaneous polarization due to symmetry breaking in the transition metal ditellurides(MTe_(2))family exhibits intriguing sliding ferroelectricity.Although theoretical predictions of MTe_(2)ferroelectric metals with noncentrosymmetric stacking have been reported,the realization of such polarization structure remains a challenge.Here,we demonstrate the synthesis of PtTe_(2)with non-centrosymmetric stacking layers,in contrast to bulk AA stacking,achieved within a scanning transmission electron microscope(STEM)by irradiating amorphous PtxTeythin flms with an electron beam probe.Cross-sectional STEM imaging combined with frst-principles calculations reveals that the diverse stacking confgurations due to an intralayerπ-stacking system break centrosymmetry in PtTe_(2),giving rise to the out-of-plane polarization.Three-dimensional atomic positions identifed by the atomic electron tomography method further demonstrate the local distortions associated with the non-centrosymmetric stacking layers in PtTe_(2).The understanding of the atomic origin of polarization in PtTe_(2)is of signifcant importance for developing devices that integrate ferroelectricity with metallicity.展开更多
基金supported by the National Natural Science Foundation of China (Grant Nos.12475012,62461160263 for P.W.,and 62276171 for H.L.)Quantum Science and Technology-National Science and Technology Major Project of China (Project No.2023ZD0300600 for P.W.)+3 种基金Guangdong Provincial Quantum Science Strategic Initiative (Grant Nos.GDZX240-3009 and GDZX2303005 for P.W.)Guangdong Basic and Applied Basic Research Foundation (Grant No.2024-A1515011938 for H.L.)Shenzhen Fundamental ResearchGeneral Project (Grant No.JCYJ20240813141503005 for H.L.)the Talents Introduction Foundation of Beijing Normal University (Grant No.310432106 for P.W.)。
文摘Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to their small gyromagnetic ratios.A promising approach to achieving high nuclear spin polarization is transferring the polarization of electrons to nuclear spins.The nitrogen-vacancy(NV)center in diamond has emerged as a highly effective medium for this purpose,and various hyperpolarization protocols have been developed.Among these,the pulsed polarization(PulsePol)method has been extensively studied due to its robustness against static energy shifts of the electron spin.In this work,we present a novel polarization protocol and uncover a family of magic sequences for hyperpolarizing nuclear spins,with PulsePol emerging as a special case of our general approach.Notably,we demonstrate that some of these magic sequences exhibit significantly greater robustness compared to the PulsePol protocol in the presence of finite half𝜋pulse duration of the protocol,Rabi and detuning errors.This enhanced robustness positions our protocol as a more suitable candidate for hyper-polarizing nuclear spins species with large gyromagnetic ratios and also ensures better compatibility with high-efficiency readout techniques at high magnetic fields.Additionally,the generality of our protocol allows for its direct application to other solid-state quantum systems beyond the NV center.
基金supported by the Key Scientific Research Project of Hunan Education Department,China(No.23A0446)the Natural Science Foundation of Hunan Province,China(provinces and cities combined)(No.2022JJ50067)+1 种基金the Hunan Province Degree and Postgraduate Teaching Reform Research Project,China(No.2022JGYB182)the Scientific Research and Innovation Foundation of Hunan University of Technology(No.CX2314).
文摘A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effect.At room temperature,a stable dual-wavelength laser and a multi-output port laser which can simultaneously emit single-wavelength lasing and dual-wavelength lasing are obtained.The signal-to-noise ratios(SNRs)for single-wavelength outputs were 54.70 dB and 57.10 dB,with power fluctuations less than 0.038 mW and 0.029 mW,respectively.For dual-wavelength lasing,the SNRs were 59.63 dB and 59.25 dB,with power fluctuations less than 0.018 mW and 0.008 mW,respectively.The center wavelength drift was less than 0.006 nm for both single-wavelength and dual-wavelength outputs.
基金co-supported by the Excellent Youth Foundation of Shanxi Province,China(No.202103021222011)the Key Research and Development project of Shanxi Province of China(No.202202020101002)+3 种基金the Fundamental Research Program of Shanxi Province of China(No.202303021211150)the Aviation Science Foundation of China(No.2022Z0220U0002)the Graduate Education Innovation Plan Project of Shanxi Province,China(No.2023KY588)the Shanxi Province Key Laboratory of Quantum Sensing and Precision Measurement,China(No.201905D121001).
文摘Autonomous navigation is a key technology for unmanned motion platforms to perform their tasks smoothly.The current approaches for daytime polarization navigation have been extensively researched.However,the polarization light intensity is the fundamental information within the polarization image,and the light intensity at night is 6-8 orders of magnitude lower than that during the day,which increase the noise and the loss of local polarization information due to occlusion,resulting in a significant decrease in the polarization orientation accuracy.Aimed at the problem,a bio-inspired model is introduced to denoise and enhance weak nighttime polarization patterns.Further,to address the issue of outlier interference in the occluded environment during practical application,a fast-fitting method of the solar meridian based on the anti-symmetric distribution of the polarization angle adjusted by Proportional and Differential(PD)control is proposed.The experimental results show that the method proposed in this paper achieves a dynamic orientation error Root Mean Square Error(RMSE)of 0.7°in the weak polarization mode at night and in the presence of local occlusion.The proposed method has strong robustness under weak polarization occlusion at night,and the orientation accuracy is improved by 97%and 80%in comparison to the least squares method,which provides a new method for polarization navigation at night.This effectively improves the robustness and environmental applicability of the bionic polarization compass for nighttime applications.
基金supported by a grant from General Scientific Research Project of Zhejiang Provincial Department of Education(No.Y202455614).
文摘Diabetes mellitus is an escalating global health issue,with 463 million adults affected in 2019.Without intervention,this number is projected to increase to 578 million by 2030 and 700 million by 2045[1].Diabetic wound,a significant complication,is characterized by delayed healing,high disability rates,and elevated mortality[2].The challenges of wound healing in diabetic patients,compounded by their high morbidity and mortality rates,have drawn growing attention in biomedical research.
基金Supported by the Central High-level Traditional Chinese Medicine Hospital Project,Eye Hospital of China Academy of Chinese Medical Sciences(No.GSP5-96,No.GSP5-83,No.GSP4-02-3)the China Postdoctoral Science Foundation(No.2025M784013)the National Natural Science Foundation of China(No.82474582,No.82174445).
文摘With the acceleration of global aging,the incidence of retinal vein occlusion(RVO)has risen markedly.Its pathogenic mechanisms are closely linked to iron dyshomeostasis and microglial polarization and agerelated degenerative changes in retinal microvessels.We systematically summarize the regulatory mechanisms of ferroptosis-an iron-dependent,lipid peroxidation-driven form of cell death,and elucidate the central pathway by which iron overload exacerbates retinal injury through the synergy of hypoxia-reoxygenation(H/R).Specifically,iron metabolic imbalance catalyzes the production of reactive oxygen species(ROS)via the Fenton reaction,which drives the polarization of microglia toward the proinflammatory M1 phenotype and activates the acyl-CoA synthetase long-chain family member 4(ACSL4)-mediated lipid peroxidation cascade.This review proposes novel insights for combinatorial therapeutic strategies targeting key ferroptotic pathways(e.g.,the SLC7A11/GPX4 axis)and modulating microglial polarization,while also addressing the translational challenges associated with iron chelators(deferoxamine),lipid peroxidation inhibitors(liproxstatin-1),and targeted delivery systems for RVO.
基金supported by the National Natural Science Foundation of China (Grant Nos. 62405231, 62405235, and 62575229)the National Key Laboratory of Space Target Awareness (Grant Nos. STA2024KGL0203, STA2024ZCA0203, and STA-24-04-05)+3 种基金the Beijing Key Laboratory of Advanced Optical Remote Sensing Technology (Grant No. AORS202405)the China Postdoctoral Science Foundation (Grant No. 2024M762527)the Shaanxi Province High-level Innovation and Entrepreneurship Talent Program (Grant No. H02439005)the Natural Science Foundation of Shaanxi (Grant Nos. S2024-JC-JCQN-60, S2025-JCQYTS-0107, and 2025JC-QYCX-05)。
文摘In complex media scattering,multiple scattering severely degrades the optical wavefront and results in blurred images,while the spectral distortion caused by the scattering effect leads to severe color distortion.Achieving color high-resolution imaging through scattering media remains a significant challenge.Here,we propose a broadband,polarization-based method for color high-resolution imaging through scattering media.This approach enables high-resolution reconstruction by effectively separating the speckle illumination pattern from the mixed-scattering field information,leveraging polarization common-mode characteristics.Concurrently,it incorporates chromatic balance compensation to correct spectral aliasing in the scattered light field,enabling color high-resolution imaging through complex scattering media.To further optimize color distortion caused by scattering,a compensation strategy combining color constancy and white balance theory is adopted.Experimental results demonstrate that the proposed method significantly enhances both spatial resolution and color fidelity across various scattering conditions and target materials,showcasing strong adaptability and robustness.This approach provides an effective solution for achieving high-resolution color optical imaging in complex scattering environments.
基金financially supported by the Hubei Key Laboratory of Pollutant Analysis&Reuse Technology(No.PA230102)。
文摘Polyurethane elastomers exhibit high dielectric constants owing to their polar groups,and can be used as energy storage capacitors.Energy storage depends not only on the dielectric constant but also on the dielectric loss.However,the relationship between chain structure and dielectric properties is not yet clear.Ketal-containing crosslinked polyurethane elastomers were prepared using cyclic ketal diol as a chain extender.The effect of the soft segment length on the dielectric properties and energy storage was investigated.The cause of the change in the dipolar polarization with the soft segment length was analyzed.As the soft segment length increased,the hard-soft hydrogen bonding decreased,whereas the hard-hard hydrogen bonding increased.Under the action of an electric field,the polar bonds in the ketal-containing polyurethane elastomer overcome the hydrogen bonding between hard-soft segments to produce polarization;meanwhile,they also experience crankshaft motions to generate polarization.The former has a relatively high relaxation activation energy of approximately 10-20 k J·mol^(-1),resulting in a large dielectric loss.The latter has a relatively low relaxation activation energy,approximately 0.7-1.7 kJ·mol^(-1),leading to low dielectric loss.As a result,the dielectric constant showed a decreasing trend,and the dielectric loss gradually decreased.This study provides a theoretical foundation for improving the dielectric properties of polyurethane elastomers.
基金funding from the National Natural Science Foundation of China (Award 91745203) supplemented by Central Universities’ Basic Research Funds.
文摘Ceramic cells promise ideal energy conversion and storage devices,making the development of efficient and robust air electrodes crucial for their application.In this study,a Ba_(0.4)Sr_(0.5)Cs_(0.1)Co_(0.7)Fe_(0.2)Nb_(0.1)O_(3−δ)(BSCCFN)air electrode,based on Ba_(0.5)Sr_(0.5)Co_(0.8)Fe_(0.2)O_(3−δ)(BSCF),is designed using a perovskite A-B-site ionic Lewis acid strength(ISA)polarization distribution strategy and is successfully applied in both oxygen-ion conducting solid oxide fuel cells(O-SOFCs)and proton-conducting reversible protonic ceramic cells(R-PCCs).When BSCCFN is used as the air electrode in O-SOFCs,a peak power density(PPD)of 1.45 W cm^(−2)is achieved at 650°C,whereas in R-PCCs,a PPD of 1.13 W cm^(−2)and a current density of−1.8 A cm^(−2)at 1.3 V are achieved at the same temperature and show stable reversibility over 100 h.Experimental measurements and theoretical calculations demonstrate that low-ISA Cs+doping accelerates the reaction kinetics of both oxygen ions and protons,while high-ISA Nb^(5+)doping enhances electrode stability.The synergistic effect of Cs^(+)and Nb^(5+)co-doping in the BSCCFN electrode lies in the ISA polarization distribution,which weakens the Co/Fe–O bond covalency,thereby promoting oxygen vacancy formation and facilitating the conduction of oxygen ions and protons.
基金supported by the National Natural Science Foundation of China(No.12275369)。
文摘Three-quasiparticle K-isomeric states in odd-mass N=106 isotones within the A~180 mass region were systematically investigated using configuration-constrained potential energy surface calculations.The calculations succes sfully reproduced the excitation energies and deformations of the known high-K isomers in nuclei from 175Tm to 181Re.For the nuclei closer to the Z=82 shell closure(^(183)Ir,^(185)Au,and^(187)Tl),predictions of the configurations of the observed and yet-to-be-observed isomers are provided.The results reveal strong shape polarization,where the three-quasiparticle states are driven to larger deformations compared to the often shape-soft or spherical ground states.A particularly rich spectrum of shape coexistence is predicted in^(187)Tl,where several high-K three-quasiparticle configurations with distinct prolate,oblate,and triaxial shapes are found to coexist at similar excitation energies.Notably,the oblate-deformed K^(π)=29/2^(+)configuration at E_(x)=1839 keV was proposed to be responsible for a long-lived isomer.This study provides a comprehensive picture of shape evolution and coexistence in high-K multi-quasiparticle states,offering valuable insights for future experimental studies.
基金supported by the Key Research and Development Project of Hainan Province(ZDYF2022SHFZ099)the Academic Enhancement Support Program of Hainan Medical University(XSTS2025040 and XSTS2025063).
文摘Objective:To investigate the effect of pectic polysaccharides isolated from Rauvolfia verticillata on ulcerative colitis and its underlying mechanisms.Methods:Pectic polysaccharides were characterized using high-performance liquid chromatography with 1-phenyl-3-methyl-5-pyrazolone pre-column derivatization,phenol-sulfuric acid assay,and gel permeation chromatography.HT-29 cells were stimulated with lipopolysaccharide and then treated with pectic polysaccharides;conditioned medium was applied to THP-1-derived macrophages to assess cell viability and polarization,while tight junction protein expression was analyzed in HT-29 cells.Furthermore,a mouse model of dextran sulfate sodium-induced colitis was treated with oral pectic polysaccharides or NOS2 overexpression.Body weight,disease activity index,colon length,histopathology,and the protein expression related to the JAK2/STAT3-NOS2 signaling were evaluated.Results:The pectic polysaccharide was characterized as an acidic pectic polysaccharide,primarily composed of galacturonic acid and various neutral sugars,with a narrow molecular weight distribution and high purity.Pectic polysaccharides significantly enhanced THP-1 macrophage viability,promoted M1 to M2 polarization,and upregulated the expression of epithelial tight junction proteins.In addition,pectic polysaccharide treatment attenuated body weight loss,lowered disease activity index scores and improved colon histology in mice with dextran sulfate sodium-induced colitis.It also reduced JAK2/STAT3 phosphorylation and NOS2 expression,and increased the expression of tight junction proteins(ZO-1,occludin,and claudin-1).Conclusions:Pectic polysaccharides attenuate ulcerative colitis by increasing M2-related macrophage markers,inhibiting the JAK2/STAT3-NOS2 signaling,and enhancing epithelial barrier-related protein expression.These findings support pectic polysaccharides as a natural candidate for the treatment of ulcerative colitis.
基金supported by the National Natural Science Foundation of China(Grants 42374215,42230209,42374199,42304183,42422406,42174185,72061147004 and 72342001)the Science and Technology Development Fund,Macao SAR(File no.0042/2024/RIA1 and 0008/2024/AKP)+1 种基金the Natural Science Foundation of Hunan Province(Grant 2023JJ20038)the Research Project of Science and Technology of Hunan Province(2025JJ10009,2022RC4025,2025QK1004,2023JJ50312,2023JJ50010 and 2024RC9012).
文摘Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordinary(L-X)modes.The role of AKR in magnetosphere−ionosphere−atmosphere coupling depends sensitively on its wave mode.While previous studies have primarily focused on the dominant R-X mode,we present the first systematic identification of all three modes using a practical polarization analysis method based on Arase satellite observations.This method employs a spin-axis-relative Ratio:when the satellite's spin axis aligns with the background magnetic field,a positive(negative)Ratio indicates the right-handed(left-handed)polarization,with reversal under anti-parallel conditions.Combined polarization-frequency analysis reveals that R-X,L-O,and L-X modes can exist in both dayside and nightside regions,with power spectral densities up to 10^(-6)mV^(2)m^(-2)Hz^(-1).This study resolves long-standing ambiguities in AKR mode classification and has implications for understanding AKR-induced electron dynamics.
基金supported by the National Natural Science Foundation of China,Nos.81930070(to SF),82002309(to ZS)the Tianjin Key Medical Discipline(Specialty)Construct Project,No.TJYXZDXK-027A(to SF)a grant from Tianjin Institute of Orthopedic Innovation and Transformation(to SF).
文摘Three-dimensional(3D)-printed hydrogel scaffolds are widely used in spinal cord injury repair,with gelatin methacrylate being particularly favored owing to its excellent biocompatibility.However,traditional scaffolds have a small contact area with tissues and lack the ability to regulate the inflammatory microenvironment.Therefore,there is a need to develop smart scaffolds with drug delivery and immune regulation functions.In this study,a 3D-printed gelatin methacrylate scaffold was developed to deliver interferon regulatory factor 4 in a targeted and sustained manner.The scaffold showed good mechanical properties,biocompatibility,and sustained interferon regulatory factor 4 release.The sustained-release interferon regulatory factor 4 competitively bound to myeloid differentiation factor 88 to inhibit the pro-inflammatory effects of interferon regulatory factor 5,and activated the signal transducer and activator of transcription 6 pathway to promote M2 macrophage polarization,thereby facilitating neural regeneration and recovery of spinal cord function.This indicates that the constructed interferon regulatory factor 4-loaded 3D-printed methyl acrylate-modified gelatin scaffold can regulate macrophage polarization through the interferon regulatory factor 4/5 axis,improve the inflammatory microenvironment after spinal cord injury,and thus provide a new target for promoting neural regeneration.
基金supported by grants from the Jiangxi Provincial Natural Science Foundation,No.20242BAB26134(to XF)the National Natural Science Foundation of China,Nos.82060638(to TC),82060222(to XF),82460237(to XF)+1 种基金the Major Disciplines of Academic and Technical Leaders Project of Jiangxi Province,Nos.20194BCJ22032(to TC),20213BCJL22049(to XF)Science and Technology Plan of Jiangxi Health Planning Committee,No.202210390(to XF).
文摘Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.However,the effect of GLP-1 on intrinsic synuclein malfunction remains unclear.In this study,we investigated the effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism in SncaA53T transgenic mice and explored the underlying mechanisms.Our data showed that Lactococcus lactis MG1363-pMG36e-GLP-1 inhibited dopaminergic neuronal death,reduced pathological aggregation ofα-synuclein,and decreased movement disorders in SncaA53T transgenic mice.Furthermore,Lactococcus lactis MG1363-pMG36e-GLP-1 downregulated lipopolysaccharide-related inflammation,reduced cerebral activation of microglia and astrocytes,and promoted cell survival via the GLP-1 receptor/PI3K/Akt pathway in the substantia nigra.Additionally,Lactococcus lactis MG1363-pMG36e-GLP-1 decreased serum levels of pro-inflammatory molecules including lipopolysaccharide,lipopolysaccharide binding protein,interleukin-1β,and interleukin-6.Gut histopathology and western blotting further revealed that Lactococcus lactis MG1363-pMG36e-GLP-1 increased the expression of gut integrity-related proteins and reduced lipopolysaccharide-related inflammation by reversing gut dysbiosis in SncaA53T transgenic mice.Our findings showed that the beneficial effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism traits in SncaA53T transgenic mice is mediated by microglial polarization and the reversal of dysbiosis.Collectively,our findings suggest that Lactococcus lactis MG1363-pMG36e-GLP-1 is a promising therapeutic agent for the treatment of Parkinson’s disease.
基金supported by the National Natural Science Foundation of China, Nos.82201474 (to GL), 82071330 (to ZT), and 92148206 (to ZT)Key Research and Discovery Program of Hubei Province, No.2021BCA109 (to ZT)。
文摘Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.
基金Supported by the National Key Research and Development Program of China(2022YFA1404602)the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0580000)+3 种基金the National Natural Science Foundation of China(U23B2045,62305362)the Program of Shanghai Academic/Technology Research Leader(22XD1424400)the Fund of SITP Innovation Foundation(CX-461 and CX-522)Special Project to Seize the Commanding Heights of Science and Technology of Chinese Academy of Sciences,subtopic(GJ0090406-6).
文摘The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.However,conventional polarization detection systems are often bulky and complex,limiting their poten⁃tial for broader applications.To address the challenges of miniaturization,integrated polarization detectors have been extensively explored in recent years,achieving significant advancements in performance and functionality.In this review,we focus mainly on integrated polarization detectors with innovative features,including infinitely high polarization discrimination,ultrahigh sensitivity to polarization state change,full Stokes parameters measure⁃ment,and simultaneous perception of polarization and other key properties of light.Lastly,we discuss the oppor⁃tunities and challenges for the future development of integrated polarization photodetectors.
基金supported by the Jilin Province Science and Technology Development Plan Item (No.20240402068GH)。
文摘To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed, based on the principle of bidirectional reflectance distribution function(BRDF), to obtain spectral reflection intensities of coatings at full spatial angles, and use polarization images to calculate the refractive index by the Fresnel equation. The index is then coupled into TorranceSparrow model to simulate the spectral scattering intensity to mutually verify the experimental results. The spectral scattering characteristics of standard camouflage patterns are then revealed and pinpoint the signature band and the angle of reflecting sensitivity.
基金supported by the National Natural Science Foundation of China (Grant Nos. 12175058 and 11921006)the National Grand Instrument Project (No. 2019YFF01014402)the Beijing Distinguished Young Scientist Program and National Grand Instrument Project No. SQ2019YFF01014400
文摘Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we propose a magnetized plasma platform for dynamic THz polarization control by exploiting the intrinsic birefringence between extraordinary and ordinary modes.We identify a strong-magnetization,zero-group-velocity-mismatch regime where the two modes share matched group velocities while retaining finite phase birefringence,enabling robust,phase-stable spin angular momentum control.By tuning the plasma length and magnetic field,we realize programmable phase retardation and demonstrate universal single-qubit gates through parameterized unitary operations.Full-wave particle-in-cell simulations validate high-fidelity polarization transformations across the Poincarésphere and demonstrate the potential for generating structured vector beams under spatially varying magnetic fields.The platform offers ultrafast response,resilience to extreme THz intensities,and in situ tunability,positioning magnetized plasmas as a versatile and damage-resilient medium for next-generation THz polarization control and structured-wave applications.
文摘As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with other fundamental properties of light,such as intensity,wavelength and phase,polarization has a shorter application history in biomedicine,because of the requirement for both advanced polarization optical components and computational approaches,which can be achieved nowadays with the fast theoretical and hardware development.
文摘BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes could have significant prognostic implications,and manipulating this polarization may offer a novel approach to controlling colorectal neoplasms.AIM To evaluate the infiltration rates of M1 and M2 macrophages in colorectal neoplasia,specifically comparing cases with and without metalloproteinase mutations.Additionally,it sought to explore potential prognostic factors as-sociated with the disease.
基金supported by the National Key R&D Program of China(Grant Nos.2024YFA1208201,2022YFA1403000,and 2021YFA1400204)the National Natural Science Foundation of China(Grant Nos.52322311,12334001,52427802,12174432,12250710675,and 52461160301)the support from Guangdong Provincial Key Laboratory of Magnetoelectric Physics and Devices(Grant No.2022B1212010008)。
文摘Spontaneous polarization due to symmetry breaking in the transition metal ditellurides(MTe_(2))family exhibits intriguing sliding ferroelectricity.Although theoretical predictions of MTe_(2)ferroelectric metals with noncentrosymmetric stacking have been reported,the realization of such polarization structure remains a challenge.Here,we demonstrate the synthesis of PtTe_(2)with non-centrosymmetric stacking layers,in contrast to bulk AA stacking,achieved within a scanning transmission electron microscope(STEM)by irradiating amorphous PtxTeythin flms with an electron beam probe.Cross-sectional STEM imaging combined with frst-principles calculations reveals that the diverse stacking confgurations due to an intralayerπ-stacking system break centrosymmetry in PtTe_(2),giving rise to the out-of-plane polarization.Three-dimensional atomic positions identifed by the atomic electron tomography method further demonstrate the local distortions associated with the non-centrosymmetric stacking layers in PtTe_(2).The understanding of the atomic origin of polarization in PtTe_(2)is of signifcant importance for developing devices that integrate ferroelectricity with metallicity.
