Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to thei...Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to their small gyromagnetic ratios.A promising approach to achieving high nuclear spin polarization is transferring the polarization of electrons to nuclear spins.The nitrogen-vacancy(NV)center in diamond has emerged as a highly effective medium for this purpose,and various hyperpolarization protocols have been developed.Among these,the pulsed polarization(PulsePol)method has been extensively studied due to its robustness against static energy shifts of the electron spin.In this work,we present a novel polarization protocol and uncover a family of magic sequences for hyperpolarizing nuclear spins,with PulsePol emerging as a special case of our general approach.Notably,we demonstrate that some of these magic sequences exhibit significantly greater robustness compared to the PulsePol protocol in the presence of finite half𝜋pulse duration of the protocol,Rabi and detuning errors.This enhanced robustness positions our protocol as a more suitable candidate for hyper-polarizing nuclear spins species with large gyromagnetic ratios and also ensures better compatibility with high-efficiency readout techniques at high magnetic fields.Additionally,the generality of our protocol allows for its direct application to other solid-state quantum systems beyond the NV center.展开更多
PRIC is honored to announce that Advances in Polar Science(APS)has been officially endorsed by the Asian Forum for Polar Sciences(AFoPS).The endorsement was formally approved by the AFoPS Committee during its annual m...PRIC is honored to announce that Advances in Polar Science(APS)has been officially endorsed by the Asian Forum for Polar Sciences(AFoPS).The endorsement was formally approved by the AFoPS Committee during its annual meeting in Goa,India,August 2025.As an endorsed journal of AFoPS,APS is now authorized to use the designation“Officially Endorsed by the Asian Forum for Polar Sciences(AFoPS)”and to display the official AFoPS logo on its website,in all print and digital editions,and across its promotional materials.展开更多
A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effe...A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effect.At room temperature,a stable dual-wavelength laser and a multi-output port laser which can simultaneously emit single-wavelength lasing and dual-wavelength lasing are obtained.The signal-to-noise ratios(SNRs)for single-wavelength outputs were 54.70 dB and 57.10 dB,with power fluctuations less than 0.038 mW and 0.029 mW,respectively.For dual-wavelength lasing,the SNRs were 59.63 dB and 59.25 dB,with power fluctuations less than 0.018 mW and 0.008 mW,respectively.The center wavelength drift was less than 0.006 nm for both single-wavelength and dual-wavelength outputs.展开更多
Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordina...Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordinary(L-X)modes.The role of AKR in magnetosphere−ionosphere−atmosphere coupling depends sensitively on its wave mode.While previous studies have primarily focused on the dominant R-X mode,we present the first systematic identification of all three modes using a practical polarization analysis method based on Arase satellite observations.This method employs a spin-axis-relative Ratio:when the satellite's spin axis aligns with the background magnetic field,a positive(negative)Ratio indicates the right-handed(left-handed)polarization,with reversal under anti-parallel conditions.Combined polarization-frequency analysis reveals that R-X,L-O,and L-X modes can exist in both dayside and nightside regions,with power spectral densities up to 10^(-6)mV^(2)m^(-2)Hz^(-1).This study resolves long-standing ambiguities in AKR mode classification and has implications for understanding AKR-induced electron dynamics.展开更多
Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease indu...Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.However,the effect of GLP-1 on intrinsic synuclein malfunction remains unclear.In this study,we investigated the effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism in SncaA53T transgenic mice and explored the underlying mechanisms.Our data showed that Lactococcus lactis MG1363-pMG36e-GLP-1 inhibited dopaminergic neuronal death,reduced pathological aggregation ofα-synuclein,and decreased movement disorders in SncaA53T transgenic mice.Furthermore,Lactococcus lactis MG1363-pMG36e-GLP-1 downregulated lipopolysaccharide-related inflammation,reduced cerebral activation of microglia and astrocytes,and promoted cell survival via the GLP-1 receptor/PI3K/Akt pathway in the substantia nigra.Additionally,Lactococcus lactis MG1363-pMG36e-GLP-1 decreased serum levels of pro-inflammatory molecules including lipopolysaccharide,lipopolysaccharide binding protein,interleukin-1β,and interleukin-6.Gut histopathology and western blotting further revealed that Lactococcus lactis MG1363-pMG36e-GLP-1 increased the expression of gut integrity-related proteins and reduced lipopolysaccharide-related inflammation by reversing gut dysbiosis in SncaA53T transgenic mice.Our findings showed that the beneficial effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism traits in SncaA53T transgenic mice is mediated by microglial polarization and the reversal of dysbiosis.Collectively,our findings suggest that Lactococcus lactis MG1363-pMG36e-GLP-1 is a promising therapeutic agent for the treatment of Parkinson’s disease.展开更多
From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its dev...From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its development.The year 2025 is a significant milestone for both global polar research and APS.APS was endorsed by the Asian Forum for Polar Sciences(AFoPS)and initiated cooperation during the 2025 AFoPS annual general meeting in India.APS will support AFoPS in planning and organizing special issues in various fields of polar science and in supporting early-career researchers from Asia in publishing their work.展开更多
Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modu...Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.展开更多
Circularly polarized luminescence(CPL)and two-photon absorption(TPA)materials have garnered considerable attentions due to their minimal energy loss and superior optical penetration[1,2].However,the current challenge ...Circularly polarized luminescence(CPL)and two-photon absorption(TPA)materials have garnered considerable attentions due to their minimal energy loss and superior optical penetration[1,2].However,the current challenge lies in the absence of well-developed strategies for designing materials that combine these two exceptional optical properties.展开更多
The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.How...The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.However,conventional polarization detection systems are often bulky and complex,limiting their poten⁃tial for broader applications.To address the challenges of miniaturization,integrated polarization detectors have been extensively explored in recent years,achieving significant advancements in performance and functionality.In this review,we focus mainly on integrated polarization detectors with innovative features,including infinitely high polarization discrimination,ultrahigh sensitivity to polarization state change,full Stokes parameters measure⁃ment,and simultaneous perception of polarization and other key properties of light.Lastly,we discuss the oppor⁃tunities and challenges for the future development of integrated polarization photodetectors.展开更多
To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed,...To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed, based on the principle of bidirectional reflectance distribution function(BRDF), to obtain spectral reflection intensities of coatings at full spatial angles, and use polarization images to calculate the refractive index by the Fresnel equation. The index is then coupled into TorranceSparrow model to simulate the spectral scattering intensity to mutually verify the experimental results. The spectral scattering characteristics of standard camouflage patterns are then revealed and pinpoint the signature band and the angle of reflecting sensitivity.展开更多
The Arctic and Antarctic regions are sensitive to global climate change.Monitoring climatological and ecological changes in such areas has become urgently necessary to address climate change and ensure sustainable hum...The Arctic and Antarctic regions are sensitive to global climate change.Monitoring climatological and ecological changes in such areas has become urgently necessary to address climate change and ensure sustainable human development.Therefore,it is important to develop automatic monitoring technology for polar regions and to produce air-ice-sea long-period,multiscale,and unmanned monitoring equipment.This paper describes an unmanned ice station observation system,the autonomous observation platform of a polar unmanned aerial vehicle,dual-use ice-sea buoys,temperature chain buoys,and a wind-solar-hydrogen storage clean energy system suitable for use in the extreme polar environment.Additionally,a coupled air-ice-sea autonomous observation station currently under development is also introduced.展开更多
Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we ...Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we propose a magnetized plasma platform for dynamic THz polarization control by exploiting the intrinsic birefringence between extraordinary and ordinary modes.We identify a strong-magnetization,zero-group-velocity-mismatch regime where the two modes share matched group velocities while retaining finite phase birefringence,enabling robust,phase-stable spin angular momentum control.By tuning the plasma length and magnetic field,we realize programmable phase retardation and demonstrate universal single-qubit gates through parameterized unitary operations.Full-wave particle-in-cell simulations validate high-fidelity polarization transformations across the Poincarésphere and demonstrate the potential for generating structured vector beams under spatially varying magnetic fields.The platform offers ultrafast response,resilience to extreme THz intensities,and in situ tunability,positioning magnetized plasmas as a versatile and damage-resilient medium for next-generation THz polarization control and structured-wave applications.展开更多
We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination unif...We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination uniformity in inertial confinement fusion(ICF)laser systems.The fundamental operating mechanism and key fabrication techniques for the SRPCP are systematically developed and experimentally validated.The SRPCP converts a linearly polarized 3ω incident laser beam into an output beam with a spatially randomized polarization distribution.When combined with a continuous phase plate,the SRPCP effectively suppresses high-intensity speckles at all spatial frequencies in the focal spot.The proposed PS technique is specifically designed for high-fluence large-aperture laser systems,enabling novel polarization control regimes in laser-driven ICF.展开更多
The significance of laser-driven polarized beam acceleration has been increasingly recognized in recent years.We propose an efficient method for generating polarized proton beams from a pre-polarized hydrogen halide g...The significance of laser-driven polarized beam acceleration has been increasingly recognized in recent years.We propose an efficient method for generating polarized proton beams from a pre-polarized hydrogen halide gas jet,utilizing magnetic vortex acceleration enhanced by a laser-driven plasma bubble.When a petawatt laser pulse passes through a pre-polarized gas jet,a bubble-like ultra-nonlinear plasma wave is formed.As a portion of the particles constituting this wave,background protons are swept by the acceleration field of the bubble and oscillate significantly along the laser propagation axis.Some of the pre-accelerated protons in the plasma wave are trapped by the acceleration field at the rear side of the target.This acceleration field is intensified by the transverse expansion of the laser-driven magnetic vortex,resulting in energetic polarized proton beams.The spin of energetic protons is determined by their precession within the electromagnetic field,which is described using the Thomas-Bargmann-Michel-Telegdi equation in analytical models and particle-in-cell simulations.Multidimensional simulations reveal that monoenergetic proton beams with an energy of hundreds of MeV,a beam charge of hundreds of pC,and a beam polarization of tens of percent can be produced at laser powers of several petawatts.Such laser-driven polarized proton beams have promise for application in polarized beam colliders,where they can be utilized to investigate particle interactions and to explore the properties of matter under extreme conditions.展开更多
Depolarizing behavior is commonly observed in most natural samples.For this reason,optical tools measuring the differences in depolarization response among spatially separated structures are highly useful in a wide ra...Depolarizing behavior is commonly observed in most natural samples.For this reason,optical tools measuring the differences in depolarization response among spatially separated structures are highly useful in a wide range of imaging applications for enhanced visualization of structures,target identification,etc.One commonly used tool for depolarizing discrimination is the so-called depolarizing spaces.In this article,we exploit the combined use of two depolarizing spaces,the indices of polarization purity(IPP)and polarizance–reflection–transformation(PRT)spaces,to improve the capability of optical systems to identify polarization–anisotropy depolarizers.The potential of these spaces to discriminate among different depolarizers is first studied from a series of simulations by incoherently adding diattenuations or retarders,with some control parameters emulating samples in nature.The simulated results demonstrate that the proposed methods are capable of increasing differences among depolarizers beyond other well-known techniques.Experimentally,validation is provided by conducting diverse phantom experiments of easy interpretation and mimicking the stated simulations.As a useful application of our approach,we developed a model able to retrieve intrinsic microscopic information of samples from macroscopic polarimetric measurements.The proposed methods enable non-invasive,straightforward,macroscopic characterization of depolarizing samples,and may be of interest for enhanced visualization of samples in multiple imaging scenarios.展开更多
The vectorial evolution of light polarization can reveal the microstructure and anisotropy of a medium beyond what can be obtained from measuring light intensity alone.However,polarization imaging in reflection geomet...The vectorial evolution of light polarization can reveal the microstructure and anisotropy of a medium beyond what can be obtained from measuring light intensity alone.However,polarization imaging in reflection geometry,which is ubiquitous and often preferred in diverse applications,has often suffered from poor and even incorrect characterization of anisotropic media.We present reciprocal polarization imaging of complex media in reflection geometry with the reciprocal polar decomposition of backscattering Mueller matrices enforcing reciprocity.We demonstrate that reciprocal polarization imaging of complex chiral and anisotropic media ac-curately quantifies their anisotropic properties in reflection geometry,whereas traditional approaches encounter difficulties and produce inferior and often erroneous results from the violation of reciprocity.In particular,reciprocal polarization imaging provides a consistent characterization of complex media of different thicknesses,accurately measures the optical activity and glucose concentration of turbid media in reflection,and discriminates between cancerous and normal tissue with even stronger contrast than forward measurement.Reciprocal polarization imaging promises broad applications of polarization optics ranging from remote sensing to bio-medicine in reflection geometries,especially in in vivo biomedical imaging,where reflection is the only feasible geometry.展开更多
This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were ide...This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were identified by Defense Meteorological Satellite Program(DMSP)F16 during the years 2011 to 2022.A temperature ratio of ion/electron temperature(T_(i)/T_(e))<0.68 is recommended to define a hot patch in the Southern Hemisphere,otherwise it is defined as a cold patch.The cold and hot patches have different dependencies on IMF clock angle,while their dependencies on IMF cone angle are similar.Both cold and hot patches appear most often on the duskside,and the distribution of cold patches gradually decreases from the dayside to the nightside,while hot patches have a higher occurrence rate near 14 and 21 magnetic local time(MLT).Moreover,we compared the key plasma characteristics of polar cap cold and hot patches in the Southern and Northern Hemispheres.The intensity of the duskside upward field-aligned current of patches in the Southern Hemisphere(SH)is stronger than that in the Northern Hemisphere(SH),which may be due to the discrepancy in conductivities between the two hemispheres,caused by the tilted dipole.In both hemispheres,the downward soft-electron energy flux of the dawnside patches is significantly greater than that of the duskside patches.展开更多
Aiming at the problem that the bit error rate(BER)of asymmetrically clipped optical orthogonal frequency division multiplexing(ACO-OFDM)space optical communication system is significantly affected by different turbule...Aiming at the problem that the bit error rate(BER)of asymmetrically clipped optical orthogonal frequency division multiplexing(ACO-OFDM)space optical communication system is significantly affected by different turbulence intensities,the deep learning technique is proposed to the polarization code decoding in ACO-OFDM space optical communication system.Moreover,this system realizes the polarization code decoding and signal demodulation without frequency conduction with superior performance and robustness compared with the performance of traditional decoder.Simulations under different turbulence intensities as well as different mapping orders show that the convolutional neural network(CNN)decoder trained under weak-medium-strong turbulence atmospheric channels achieves a performance improvement of about 10^(2)compared to the conventional decoder at 4-quadrature amplitude modulation(4QAM),and the BERs for both 16QAM and 64QAM are in between those of the conventional decoder.展开更多
As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with othe...As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with other fundamental properties of light,such as intensity,wavelength and phase,polarization has a shorter application history in biomedicine,because of the requirement for both advanced polarization optical components and computational approaches,which can be achieved nowadays with the fast theoretical and hardware development.展开更多
BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes co...BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes could have significant prognostic implications,and manipulating this polarization may offer a novel approach to controlling colorectal neoplasms.AIM To evaluate the infiltration rates of M1 and M2 macrophages in colorectal neoplasia,specifically comparing cases with and without metalloproteinase mutations.Additionally,it sought to explore potential prognostic factors as-sociated with the disease.展开更多
基金supported by the National Natural Science Foundation of China (Grant Nos.12475012,62461160263 for P.W.,and 62276171 for H.L.)Quantum Science and Technology-National Science and Technology Major Project of China (Project No.2023ZD0300600 for P.W.)+3 种基金Guangdong Provincial Quantum Science Strategic Initiative (Grant Nos.GDZX240-3009 and GDZX2303005 for P.W.)Guangdong Basic and Applied Basic Research Foundation (Grant No.2024-A1515011938 for H.L.)Shenzhen Fundamental ResearchGeneral Project (Grant No.JCYJ20240813141503005 for H.L.)the Talents Introduction Foundation of Beijing Normal University (Grant No.310432106 for P.W.)。
文摘Hyperpolarization of nuclear spins is crucial for advancing nuclear magnetic resonance and quantum information technologies,as nuclear spins typically exhibit extremely low polarization at room temperature due to their small gyromagnetic ratios.A promising approach to achieving high nuclear spin polarization is transferring the polarization of electrons to nuclear spins.The nitrogen-vacancy(NV)center in diamond has emerged as a highly effective medium for this purpose,and various hyperpolarization protocols have been developed.Among these,the pulsed polarization(PulsePol)method has been extensively studied due to its robustness against static energy shifts of the electron spin.In this work,we present a novel polarization protocol and uncover a family of magic sequences for hyperpolarizing nuclear spins,with PulsePol emerging as a special case of our general approach.Notably,we demonstrate that some of these magic sequences exhibit significantly greater robustness compared to the PulsePol protocol in the presence of finite half𝜋pulse duration of the protocol,Rabi and detuning errors.This enhanced robustness positions our protocol as a more suitable candidate for hyper-polarizing nuclear spins species with large gyromagnetic ratios and also ensures better compatibility with high-efficiency readout techniques at high magnetic fields.Additionally,the generality of our protocol allows for its direct application to other solid-state quantum systems beyond the NV center.
文摘PRIC is honored to announce that Advances in Polar Science(APS)has been officially endorsed by the Asian Forum for Polar Sciences(AFoPS).The endorsement was formally approved by the AFoPS Committee during its annual meeting in Goa,India,August 2025.As an endorsed journal of AFoPS,APS is now authorized to use the designation“Officially Endorsed by the Asian Forum for Polar Sciences(AFoPS)”and to display the official AFoPS logo on its website,in all print and digital editions,and across its promotional materials.
基金supported by the Key Scientific Research Project of Hunan Education Department,China(No.23A0446)the Natural Science Foundation of Hunan Province,China(provinces and cities combined)(No.2022JJ50067)+1 种基金the Hunan Province Degree and Postgraduate Teaching Reform Research Project,China(No.2022JGYB182)the Scientific Research and Innovation Foundation of Hunan University of Technology(No.CX2314).
文摘A dual-wavelength ring-cavity erbium-doped fiber(EDF)laser is designed based on two polarization beam splitters(PBSs)and a polarization controller(PC)performing gain equalization and polarization hole burning(PHB)effect.At room temperature,a stable dual-wavelength laser and a multi-output port laser which can simultaneously emit single-wavelength lasing and dual-wavelength lasing are obtained.The signal-to-noise ratios(SNRs)for single-wavelength outputs were 54.70 dB and 57.10 dB,with power fluctuations less than 0.038 mW and 0.029 mW,respectively.For dual-wavelength lasing,the SNRs were 59.63 dB and 59.25 dB,with power fluctuations less than 0.018 mW and 0.008 mW,respectively.The center wavelength drift was less than 0.006 nm for both single-wavelength and dual-wavelength outputs.
基金supported by the National Natural Science Foundation of China(Grants 42374215,42230209,42374199,42304183,42422406,42174185,72061147004 and 72342001)the Science and Technology Development Fund,Macao SAR(File no.0042/2024/RIA1 and 0008/2024/AKP)+1 种基金the Natural Science Foundation of Hunan Province(Grant 2023JJ20038)the Research Project of Science and Technology of Hunan Province(2025JJ10009,2022RC4025,2025QK1004,2023JJ50312,2023JJ50010 and 2024RC9012).
文摘Auroral kilometric radiation(AKR),a fundamental plasma emission in Earth's magnetosphere,exhibits three characteristic modes:the right-handed extraordinary(R-X),left-handed ordinary(L-O)and left-handed extraordinary(L-X)modes.The role of AKR in magnetosphere−ionosphere−atmosphere coupling depends sensitively on its wave mode.While previous studies have primarily focused on the dominant R-X mode,we present the first systematic identification of all three modes using a practical polarization analysis method based on Arase satellite observations.This method employs a spin-axis-relative Ratio:when the satellite's spin axis aligns with the background magnetic field,a positive(negative)Ratio indicates the right-handed(left-handed)polarization,with reversal under anti-parallel conditions.Combined polarization-frequency analysis reveals that R-X,L-O,and L-X modes can exist in both dayside and nightside regions,with power spectral densities up to 10^(-6)mV^(2)m^(-2)Hz^(-1).This study resolves long-standing ambiguities in AKR mode classification and has implications for understanding AKR-induced electron dynamics.
基金supported by grants from the Jiangxi Provincial Natural Science Foundation,No.20242BAB26134(to XF)the National Natural Science Foundation of China,Nos.82060638(to TC),82060222(to XF),82460237(to XF)+1 种基金the Major Disciplines of Academic and Technical Leaders Project of Jiangxi Province,Nos.20194BCJ22032(to TC),20213BCJL22049(to XF)Science and Technology Plan of Jiangxi Health Planning Committee,No.202210390(to XF).
文摘Parkinson’s disease is characterized by synucleinopathy-associated neurodegeneration.Previous studies have shown that glucagon-like peptide-1(GLP-1)has beneficial effects in a mouse model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.However,the effect of GLP-1 on intrinsic synuclein malfunction remains unclear.In this study,we investigated the effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism in SncaA53T transgenic mice and explored the underlying mechanisms.Our data showed that Lactococcus lactis MG1363-pMG36e-GLP-1 inhibited dopaminergic neuronal death,reduced pathological aggregation ofα-synuclein,and decreased movement disorders in SncaA53T transgenic mice.Furthermore,Lactococcus lactis MG1363-pMG36e-GLP-1 downregulated lipopolysaccharide-related inflammation,reduced cerebral activation of microglia and astrocytes,and promoted cell survival via the GLP-1 receptor/PI3K/Akt pathway in the substantia nigra.Additionally,Lactococcus lactis MG1363-pMG36e-GLP-1 decreased serum levels of pro-inflammatory molecules including lipopolysaccharide,lipopolysaccharide binding protein,interleukin-1β,and interleukin-6.Gut histopathology and western blotting further revealed that Lactococcus lactis MG1363-pMG36e-GLP-1 increased the expression of gut integrity-related proteins and reduced lipopolysaccharide-related inflammation by reversing gut dysbiosis in SncaA53T transgenic mice.Our findings showed that the beneficial effect of Lactococcus lactis MG1363-pMG36e-GLP-1 on parkinsonism traits in SncaA53T transgenic mice is mediated by microglial polarization and the reversal of dysbiosis.Collectively,our findings suggest that Lactococcus lactis MG1363-pMG36e-GLP-1 is a promising therapeutic agent for the treatment of Parkinson’s disease.
文摘From its founding in 1990 as Antarctic Research(English version)to the autumn issue in 2025(this issue),Advances in Polar Science(APS)has published a total of 100 issues,marking the beginning of a new stage in its development.The year 2025 is a significant milestone for both global polar research and APS.APS was endorsed by the Asian Forum for Polar Sciences(AFoPS)and initiated cooperation during the 2025 AFoPS annual general meeting in India.APS will support AFoPS in planning and organizing special issues in various fields of polar science and in supporting early-career researchers from Asia in publishing their work.
基金supported by the National Natural Science Foundation of China, Nos.82201474 (to GL), 82071330 (to ZT), and 92148206 (to ZT)Key Research and Discovery Program of Hubei Province, No.2021BCA109 (to ZT)。
文摘Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.
基金supported by NSFC(22271282)the Self-deployment Project Research Program of Haixi Institutes,Chinese Academy of Sciences with the grant number of CXZX-2022-JQ04.
文摘Circularly polarized luminescence(CPL)and two-photon absorption(TPA)materials have garnered considerable attentions due to their minimal energy loss and superior optical penetration[1,2].However,the current challenge lies in the absence of well-developed strategies for designing materials that combine these two exceptional optical properties.
基金Supported by the National Key Research and Development Program of China(2022YFA1404602)the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0580000)+3 种基金the National Natural Science Foundation of China(U23B2045,62305362)the Program of Shanghai Academic/Technology Research Leader(22XD1424400)the Fund of SITP Innovation Foundation(CX-461 and CX-522)Special Project to Seize the Commanding Heights of Science and Technology of Chinese Academy of Sciences,subtopic(GJ0090406-6).
文摘The polarization properties of light are widely applied in imaging,communications,materials analy⁃sis,and life sciences.Various methods have been developed that can measure the polarization information of a target.However,conventional polarization detection systems are often bulky and complex,limiting their poten⁃tial for broader applications.To address the challenges of miniaturization,integrated polarization detectors have been extensively explored in recent years,achieving significant advancements in performance and functionality.In this review,we focus mainly on integrated polarization detectors with innovative features,including infinitely high polarization discrimination,ultrahigh sensitivity to polarization state change,full Stokes parameters measure⁃ment,and simultaneous perception of polarization and other key properties of light.Lastly,we discuss the oppor⁃tunities and challenges for the future development of integrated polarization photodetectors.
基金supported by the Jilin Province Science and Technology Development Plan Item (No.20240402068GH)。
文摘To identify coatings and analyze the anti-detection capabilities of camouflage patterns, material samples can be prepared using the super-pixel segmentation method. A spectral polarization imaging system is developed, based on the principle of bidirectional reflectance distribution function(BRDF), to obtain spectral reflection intensities of coatings at full spatial angles, and use polarization images to calculate the refractive index by the Fresnel equation. The index is then coupled into TorranceSparrow model to simulate the spectral scattering intensity to mutually verify the experimental results. The spectral scattering characteristics of standard camouflage patterns are then revealed and pinpoint the signature band and the angle of reflecting sensitivity.
基金supported by the National Key Research and Development Program of China(Grant no.2022YFC2807603)。
文摘The Arctic and Antarctic regions are sensitive to global climate change.Monitoring climatological and ecological changes in such areas has become urgently necessary to address climate change and ensure sustainable human development.Therefore,it is important to develop automatic monitoring technology for polar regions and to produce air-ice-sea long-period,multiscale,and unmanned monitoring equipment.This paper describes an unmanned ice station observation system,the autonomous observation platform of a polar unmanned aerial vehicle,dual-use ice-sea buoys,temperature chain buoys,and a wind-solar-hydrogen storage clean energy system suitable for use in the extreme polar environment.Additionally,a coupled air-ice-sea autonomous observation station currently under development is also introduced.
基金supported by the National Natural Science Foundation of China (Grant Nos. 12175058 and 11921006)the National Grand Instrument Project (No. 2019YFF01014402)the Beijing Distinguished Young Scientist Program and National Grand Instrument Project No. SQ2019YFF01014400
文摘Controlling terahertz(THz)polarization with high stability and tunability is essential for achieving further progress in ultrafast spectroscopy,structured-light manipulation,and quantum information processing.Here,we propose a magnetized plasma platform for dynamic THz polarization control by exploiting the intrinsic birefringence between extraordinary and ordinary modes.We identify a strong-magnetization,zero-group-velocity-mismatch regime where the two modes share matched group velocities while retaining finite phase birefringence,enabling robust,phase-stable spin angular momentum control.By tuning the plasma length and magnetic field,we realize programmable phase retardation and demonstrate universal single-qubit gates through parameterized unitary operations.Full-wave particle-in-cell simulations validate high-fidelity polarization transformations across the Poincarésphere and demonstrate the potential for generating structured vector beams under spatially varying magnetic fields.The platform offers ultrafast response,resilience to extreme THz intensities,and in situ tunability,positioning magnetized plasmas as a versatile and damage-resilient medium for next-generation THz polarization control and structured-wave applications.
基金supported by the National Natural Science Foundation of China(Grant No.62275235).
文摘We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination uniformity in inertial confinement fusion(ICF)laser systems.The fundamental operating mechanism and key fabrication techniques for the SRPCP are systematically developed and experimentally validated.The SRPCP converts a linearly polarized 3ω incident laser beam into an output beam with a spatially randomized polarization distribution.When combined with a continuous phase plate,the SRPCP effectively suppresses high-intensity speckles at all spatial frequencies in the focal spot.The proposed PS technique is specifically designed for high-fluence large-aperture laser systems,enabling novel polarization control regimes in laser-driven ICF.
基金supported by the National Natural Science Foundation of China(Grant Nos.12075081 and 12404395)the Innovation Group Project of the Natural Science Foundation of Hubei Province of China(Grant No.2024AFA038)Bin Liu acknowledges the support of Guangdong High Level Innovation Research Institute Project,Grant No.2021B0909050006.
文摘The significance of laser-driven polarized beam acceleration has been increasingly recognized in recent years.We propose an efficient method for generating polarized proton beams from a pre-polarized hydrogen halide gas jet,utilizing magnetic vortex acceleration enhanced by a laser-driven plasma bubble.When a petawatt laser pulse passes through a pre-polarized gas jet,a bubble-like ultra-nonlinear plasma wave is formed.As a portion of the particles constituting this wave,background protons are swept by the acceleration field of the bubble and oscillate significantly along the laser propagation axis.Some of the pre-accelerated protons in the plasma wave are trapped by the acceleration field at the rear side of the target.This acceleration field is intensified by the transverse expansion of the laser-driven magnetic vortex,resulting in energetic polarized proton beams.The spin of energetic protons is determined by their precession within the electromagnetic field,which is described using the Thomas-Bargmann-Michel-Telegdi equation in analytical models and particle-in-cell simulations.Multidimensional simulations reveal that monoenergetic proton beams with an energy of hundreds of MeV,a beam charge of hundreds of pC,and a beam polarization of tens of percent can be produced at laser powers of several petawatts.Such laser-driven polarized proton beams have promise for application in polarized beam colliders,where they can be utilized to investigate particle interactions and to explore the properties of matter under extreme conditions.
基金supported by the China Scholarship Council(Grant No.202306690024)the Ministerio de Ciencia e Innovación and Fondos FEDER(Grant Nos.PID2021-562126509OB-C21 and PDC2022-133332-C21)+1 种基金the Generalitat de Catalunya(Grant No.2021SGR00138)the Beatriu de Pinós Fellowship(Grant No.2021-BP-00206).
文摘Depolarizing behavior is commonly observed in most natural samples.For this reason,optical tools measuring the differences in depolarization response among spatially separated structures are highly useful in a wide range of imaging applications for enhanced visualization of structures,target identification,etc.One commonly used tool for depolarizing discrimination is the so-called depolarizing spaces.In this article,we exploit the combined use of two depolarizing spaces,the indices of polarization purity(IPP)and polarizance–reflection–transformation(PRT)spaces,to improve the capability of optical systems to identify polarization–anisotropy depolarizers.The potential of these spaces to discriminate among different depolarizers is first studied from a series of simulations by incoherently adding diattenuations or retarders,with some control parameters emulating samples in nature.The simulated results demonstrate that the proposed methods are capable of increasing differences among depolarizers beyond other well-known techniques.Experimentally,validation is provided by conducting diverse phantom experiments of easy interpretation and mimicking the stated simulations.As a useful application of our approach,we developed a model able to retrieve intrinsic microscopic information of samples from macroscopic polarimetric measurements.The proposed methods enable non-invasive,straightforward,macroscopic characterization of depolarizing samples,and may be of interest for enhanced visualization of samples in multiple imaging scenarios.
基金upported by the Natural Science Foundation of Zhejiang Province(Grant No.LZ16H180002)the National Natural Science Foundation of China(Grant No.61905181)+1 种基金the Wenzhou Municipal Science and Technology Bureau(Grant No.ZS2017022)the National Science Foundation of the U.S.(Grant No.1607664).
文摘The vectorial evolution of light polarization can reveal the microstructure and anisotropy of a medium beyond what can be obtained from measuring light intensity alone.However,polarization imaging in reflection geometry,which is ubiquitous and often preferred in diverse applications,has often suffered from poor and even incorrect characterization of anisotropic media.We present reciprocal polarization imaging of complex media in reflection geometry with the reciprocal polar decomposition of backscattering Mueller matrices enforcing reciprocity.We demonstrate that reciprocal polarization imaging of complex chiral and anisotropic media ac-curately quantifies their anisotropic properties in reflection geometry,whereas traditional approaches encounter difficulties and produce inferior and often erroneous results from the violation of reciprocity.In particular,reciprocal polarization imaging provides a consistent characterization of complex media of different thicknesses,accurately measures the optical activity and glucose concentration of turbid media in reflection,and discriminates between cancerous and normal tissue with even stronger contrast than forward measurement.Reciprocal polarization imaging promises broad applications of polarization optics ranging from remote sensing to bio-medicine in reflection geometries,especially in in vivo biomedical imaging,where reflection is the only feasible geometry.
基金supported by the National Natural Science Foundation of China(Grants 42325404,42120104003,42204164,42474219 and U22A2006)the Chinese Meridian Project,the International Partnership Program of Chinese Academy of Sciences(Grant 183311KYSB20200003)+7 种基金Shandong Provincial Natural Science Foundation(Grants ZR2022QD077,ZR2022MD034)the Stable-Support Scientific Project of China Research Institute of Radiowave Propagation(Grant A132312191)the foundation of the National Key Laboratory of Electromagnetic Environment(Grant 6142403180204)the Chongqing Natural Science Foundation(Grants cstc2021ycjh-bgzxm0072,CSTB2023NSCQ-LZX0082)National Program on Key Basic Research Project(Grant 2022173-SD-1)The work in Norway is supported by the Research Council of Norway Grant 326039Work at UCLA has been supported by NSF grant AGS-2055192This research was supported by the International Space Science Institute(ISSI)in Bern and Beijing,through ISSI International Team project#511(Multi-Scale Magnetosphere-Ionosphere-Thermosphere Interaction).
文摘This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were identified by Defense Meteorological Satellite Program(DMSP)F16 during the years 2011 to 2022.A temperature ratio of ion/electron temperature(T_(i)/T_(e))<0.68 is recommended to define a hot patch in the Southern Hemisphere,otherwise it is defined as a cold patch.The cold and hot patches have different dependencies on IMF clock angle,while their dependencies on IMF cone angle are similar.Both cold and hot patches appear most often on the duskside,and the distribution of cold patches gradually decreases from the dayside to the nightside,while hot patches have a higher occurrence rate near 14 and 21 magnetic local time(MLT).Moreover,we compared the key plasma characteristics of polar cap cold and hot patches in the Southern and Northern Hemispheres.The intensity of the duskside upward field-aligned current of patches in the Southern Hemisphere(SH)is stronger than that in the Northern Hemisphere(SH),which may be due to the discrepancy in conductivities between the two hemispheres,caused by the tilted dipole.In both hemispheres,the downward soft-electron energy flux of the dawnside patches is significantly greater than that of the duskside patches.
基金supported by the National Natural Science Foundation of China(No.12104141).
文摘Aiming at the problem that the bit error rate(BER)of asymmetrically clipped optical orthogonal frequency division multiplexing(ACO-OFDM)space optical communication system is significantly affected by different turbulence intensities,the deep learning technique is proposed to the polarization code decoding in ACO-OFDM space optical communication system.Moreover,this system realizes the polarization code decoding and signal demodulation without frequency conduction with superior performance and robustness compared with the performance of traditional decoder.Simulations under different turbulence intensities as well as different mapping orders show that the convolutional neural network(CNN)decoder trained under weak-medium-strong turbulence atmospheric channels achieves a performance improvement of about 10^(2)compared to the conventional decoder at 4-quadrature amplitude modulation(4QAM),and the BERs for both 16QAM and 64QAM are in between those of the conventional decoder.
文摘As a vectorial property,polarization encodes high-dimensional information of light.Polarization-based imaging can characterize detailed structural features of biomedical samples label-freely.However,compared with other fundamental properties of light,such as intensity,wavelength and phase,polarization has a shorter application history in biomedicine,because of the requirement for both advanced polarization optical components and computational approaches,which can be achieved nowadays with the fast theoretical and hardware development.
文摘BACKGROUND Macrophages play a crucial role in the tumor microenvironment,displaying remarkable plasticity that allows them to either suppress or promote tumor progression.Their polarization into M1 or M2 phenotypes could have significant prognostic implications,and manipulating this polarization may offer a novel approach to controlling colorectal neoplasms.AIM To evaluate the infiltration rates of M1 and M2 macrophages in colorectal neoplasia,specifically comparing cases with and without metalloproteinase mutations.Additionally,it sought to explore potential prognostic factors as-sociated with the disease.
