Aim: To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. Methods: From January 1992 to January 2002, 106 young patient...Aim: To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. Methods: From January 1992 to January 2002, 106 young patients underwent surgical correction of congenital penile curvature by corporeal plication. Indications for operation were difficult or impossible vaginal penetration and cosmetic problems. The technique of corporeal plication consists of placing longitudinal plication sutures of 2-zero braided polyester on the convex side of the curvature until the curvature is corrected when erection is artificially induced. Results of this procedure were obtained by retrospective chart reviews and questionnaires via mail. Long-term follow-up ranged from 11 to 132 (mean 69.3) months and data were available for 68 patients. Results: Penile straightening was excellent in 62 patients (91 %) and good with less than 15 degree of residual curvature in 6 patients (9 %). Sixty-seven patients reported no change in erectile rigidity or maintenance postoperatively, while 1 described early detumescence. Shortening of the penis without functional problems was noted by 26 patients (38 %). Thirty-Five patients (51 %) reported feeling palpable indurations (suture knots) on the penis. Temporary numbness of glans penis was described in 3 patients. Overall, 60 patients were very satisfied, 6 satisfied, 2 unsatisfied. Conclusion: Corporeal plication is an effective and durable procedure with a high rate of patient satisfaction.展开更多
General recommendations regarding surgical techniques are not always appropriate for all Peyronie’s disease(PD)patients.Therefore,the purpose of this study was to investigate the effects of plication procedures in PD...General recommendations regarding surgical techniques are not always appropriate for all Peyronie’s disease(PD)patients.Therefore,the purpose of this study was to investigate the effects of plication procedures in PD patients with severe penile curvature and the effects of early surgical correction in patients who no longer have progressive deformities.The clinical data from 72 patients who underwent plication procedures were analyzed in this study.Patients were divided into Groups A and B according to the curvature severity(≤60°or>60°)and Groups 1 and 2 according to the duration of disease stabilization(≥3 months or<3 months).At the 1-year follow-up,90.0%(36/40)and 90.6%(29/32)patients reported complete penile straightening,and 60.0%(24/40)and 100.0%(32/32)patients reported penile shortening in Groups A and B,respectively.No curvature recurrence occurred in any patient,and no significant differences were observed in postoperative International Index of Erectile Function–Erectile Function domain(IIEF-EF),erectile pain,sensitivity,or suture knots on the penis whether such outcomes were grouped according to the curvature severity or the duration of stabilization.However,the duration from symptom onset to surgical management in Group 1 was significantly longer than that in Group 2(mean±standard deviation[s.d.]:20.9±2.0 months and 14.3±1.2 months,respectively,P<0.001).The present study showed that the plication procedures seemed to be an effective choice for the surgical treatment of PD patients with severe penile curvature.In addition,the early surgical treatment seemed to benefit those patients who already had no erectile pain and no longer exhibited progressive deformity.展开更多
The present objective is to observe the side effects and complications of fem ale tubalsterilization by phenol-atabrinepaste (PAP) and phenolm ucilage (PM). 1 705 eligible w om en w ere divided random ly into tw o g...The present objective is to observe the side effects and complications of fem ale tubalsterilization by phenol-atabrinepaste (PAP) and phenolm ucilage (PM). 1 705 eligible w om en w ere divided random ly into tw o groups, 871 usinig PAP and 834 w om en using PM. Results: Thefeverratesw ere8.0and 4.4( P< 0.01 ) respec- tively in group PAP and group PM. Infection rates of the appendages w ere 2.3 and 1.2 respectively. The incidence of chem ical peritonitis, w ithin the lim its of pelvic cavity, w ere 1.1and 2.4respectively. Perforation of uterus, pelvic ab- scessand ectopicpregnancy w ere notfound during thisobservation. Slightabdom inal pain after the proceduresw ere 33.6and 30.8respectively. Slightvaginalbleed- ing after the procedure w as 23.2 and 18.0 respectively. Menstruation of the w om en w as not affected by the instillation. This five-year follow -up study neither show ed a positivePap testnor a potentialdeseasecaused by thesterilizing agents. This technique isa safe and efficientm ethod for fem ale sterilization.展开更多
Objective: This study seeks to evaluate the results of surgery performed according to the etiological causes of diaphragmatic eventration or paralysis. Method: Files of 54 patients (35 males, 19 females;mean age: 39.1...Objective: This study seeks to evaluate the results of surgery performed according to the etiological causes of diaphragmatic eventration or paralysis. Method: Files of 54 patients (35 males, 19 females;mean age: 39.1 ± 3.01 years) who had undergone diaphragm plication between January 2005 and June 2011 in two clinics located in Istanbul were studied in terms of pulmonary spirometry, applied surgical procedure, duration of hospitalization, morbidity, and mortality. Results: In diaphragm plications, observed etiologies were isolated diaphragmatic eventration without phrenic nerve injury (Group 1) in 20 (37%) patients due to blunt thoracic trauma;Group 2 (thymoma in 19 (35.2%) patients;lung cancer in 7 (12.9%) patients;mediastinal tumor in 3 (5.6%) patients) and congenital heart surgery (Group 3) in 5 (9.3%) patients. The mean time to plication was 7.4 months in Group 1. The mean duration of hospitalization was 4 days in Group 1, 6.2 days in Group 2, 11.8 days in Group 3. Mean forced vital capacity, forced expiratory volume at 1 second improved by 17%, 20.3%, respectively (p In Group 1, mean dyspnea-related hospital admission before plication was 2.4 times. At the end of 6 months after plication mean dyspnea-related hospital admission was 0 time. All of them returned to daily activities or their job within 6 months in Group 1. Postoperative mortality was observed in 2 (3.7%) patients in Group 3 while the overall complication rates were 24%. The morbidity rates were 8%, 27.5%, 60%, respectively;and the mortality rates were 0%, 0%, 40%, respectively. Conclusion: As a result, it could be suggested that early and timely performed plications for diaphragmatic eventration improves functional status and assesses a shorter lenght of stay. On the other hand,simultaneously performed plications in intraoperative phrenic nerve resections can be performed with acceptable morbidity and no mortality. In diaphragmatic paralysis due to congenital heart surgery, morbidity and mortality rate is still high.展开更多
Point-through-point acupuncture is atechnique in which a long needle is insertedin various directions and depths and acts ontwo or more points in treating disease.It iscommonly used in clinical practice.The ap-plicati...Point-through-point acupuncture is atechnique in which a long needle is insertedin various directions and depths and acts ontwo or more points in treating disease.It iscommonly used in clinical practice.The ap-plication of point-through-point acupunc-ture and its effects are summarized as fol-lows.展开更多
Surgical ventricular restoration (SVR) procedures have been developed;however, their long-term effectiveness remains controversial. Although a series of endoventricular spiral plication (ESP) has been rarely reported ...Surgical ventricular restoration (SVR) procedures have been developed;however, their long-term effectiveness remains controversial. Although a series of endoventricular spiral plication (ESP) has been rarely reported and its long prognosis is still unknown;this method has a unique concept of left ventricular (LV) restoration without artificial patch materials. Here, we describe the case of a patient with ischemic cardiomyopathy and ischemic mitral regurgitation who successfully underwent ESP, mitral valve repair, and coronary artery bypass grafting. ESP was effective in papillary muscle approximation for avoiding heart failure;however, the noted improvement of LV wall thickening might be temporary.展开更多
Diaphragm eventration or paralysis causes elevation of the ipsilateral diaphragm. Some patients have symptoms. The most common symptom is dyspnea. In symptomatic patients with unilateral diaphragm paralysis and dyspne...Diaphragm eventration or paralysis causes elevation of the ipsilateral diaphragm. Some patients have symptoms. The most common symptom is dyspnea. In symptomatic patients with unilateral diaphragm paralysis and dyspnea disproportionate to the degree of physical activity, diaphragm plication is the treatment of choice to relieve dyspnea. We report on our experience with laparoscopic plication of a paralysed hemidiaphragm. The laparoscopic approach is an attractive surgical alternative for the treatment of phrenic nerve palsy. This technique combines the advantage of an excellent field of vision during surgery with a fast postoperative recovery and early discharge from hospital. In accordance to recent literature, we have successfully applied the laparoscopic approach to treat our patients who suffered from a unilateral paralysis of the diaphragm. Preoperative symptoms of exertional dyspnea and orthopnea were significantly reduced.展开更多
Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Assoc...Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.展开更多
Phrenic nerve injury can occur as a complication of lung transplantation. A 54-year-old man underwent single-lung transplantation due to interstitial pneumonia. The patient required circulatory support with venoarteri...Phrenic nerve injury can occur as a complication of lung transplantation. A 54-year-old man underwent single-lung transplantation due to interstitial pneumonia. The patient required circulatory support with venoarterial extracorporeal membrane oxygenation and was unable to be weaned from ventilatory support with nitric oxide. Although enhanced CT scanning showed stenotic anastomosis of the right pulmonary artery (PA), pulmonary angiograph findings revealed that PA flow was normal under sedation and considerably decreased with spontaneous breathing. Fluoroscopy showed that the right diaphragm moved inversely to the position of the left diaphragm, indicating that the right phrenic nerve was paralytic. We performed diaphragmatic plication 7 days after lung transplantation and weaning from ventilator support was accomplished soon thereafter. Phrenic nerve dysfunction is an important clinical problem following lung transplantation. In the present case, diaphragmatic plication was effective for treatment of circulatory failure due to phrenic nerve paralysis even in acute phase after lung transplantation.展开更多
Background:In this study,we aimed to evaluate the efficacy of dorsal plication(DP)in correcting mild-to-moderate ventral penile cur-vature(VPC)during primary hypospadias repair with urethral plate preservation.Materia...Background:In this study,we aimed to evaluate the efficacy of dorsal plication(DP)in correcting mild-to-moderate ventral penile cur-vature(VPC)during primary hypospadias repair with urethral plate preservation.Materials and methods:We retrospectively reviewed medical records of patients who underwent DP during primary hypospadias re-pair with urethral plate preservation between January 2018 and December 2021.Patients were categorized into 2 groups based on the degree of curvature following degloving:<30°(group 1)and 30°to 40°(group 2).Recurrent VPC,urethral complications,and pediatric penile perception scores were analyzed.Results:Seventy-six patients met the inclusion criteria:59 in group 1 and 17 in group 2.The incidences of recurrent VPC(1.7%vs.5.9%;p=0.928)and urethral complications(32.2%vs.29.4%;p=0.827)were comparable between groups.A total of 29 completed pediatric penile perception scores questionnaires were collected.No significant difference was observed in dissatisfaction with penile length(13.6%vs.14.3%;p=0.692).Conclusions:Dorsal plication did not increase the rates of VPC recurrence,urethral complications,or dissatisfaction with penile length in cases with 30°to 40°VPC after degloving.Long-term follow-up with larger sample sizes is warranted to further assess the efficacy of DP.展开更多
With the support by the National Natural Science Foundation of China through the Collaborative Innovation Center of Chemistry for Energy Materials,and Qian-ren fund from the University of Science and Technology of Chi...With the support by the National Natural Science Foundation of China through the Collaborative Innovation Center of Chemistry for Energy Materials,and Qian-ren fund from the University of Science and Technology of China,the research team led by Prof.Zeng Xiaocheng(曾晓成)at the University of Science and Technology of China and the University of Nebraska-Lincoln,cooperated with the research team展开更多
Objective To detect the plasma concentration of OLC1(overexpressed in lung cancer 1)protein as a potential cancer biomarker,and evaluating its clinical application value in the diagnosis of non-small cell lung cancer(...Objective To detect the plasma concentration of OLC1(overexpressed in lung cancer 1)protein as a potential cancer biomarker,and evaluating its clinical application value in the diagnosis of non-small cell lung cancer(NSCLC).Methods We prepared OLC1 antibody with OLC1 full length protein,in 5-6-week old Bal B/c mice.Each mouse was immunized four times at a dose展开更多
Background:Numerous surgical techniques are available for the correction of isolated ventral congenital penile curvature(IVCPC).This study aimed to assess the outcomes and predictors of IVCPC treatment in adults using...Background:Numerous surgical techniques are available for the correction of isolated ventral congenital penile curvature(IVCPC).This study aimed to assess the outcomes and predictors of IVCPC treatment in adults using an incisionless plication technique.Materials and methods:This prospective case series examined patients with IVCPC who were treated in our hospital between October 2017 and February 2020 using incisionless plication of the tunica albuginea(Essed-Schroeder technique)with a covering pair of absorbable sutures.The primary outcomes were successful correction(defined as a residual curvature≤15 degrees)and patient satisfaction.Postoperative follow-ups were performed at 3,6,and 12 months.Results:A total of 23 patients were treated for IVCPC with a mean(range)age of 25.3(18-31)years.Eighteen patients(78.3%)were single with cosmetic complaints,whereas the other 5 patients(21.7%)were married and presented with a difficult vaginal intromission.The mean(range)curvature,length,and operative time were 40(30-50)degrees,15(10-19)cm,and 82(65-100)minutes,respectively.Postoperative penile pain and numbness occurred in 13 patients(56.5%)and 7 patients(30.4%)only within the first month,respectively.Palpable suture knots were reported in 15 patients(65.5%)without being bothersome up to 12 months.The postoperative means(ranges)of penile curvature and length were significantly different from that of the preoperative values at 3(5[0-20]degrees and 14.5[9-18.5]cm),6(5[0-20]degrees and 14.5[9-18.5]cm),and 12 months(5[0-30]degrees and 14.5[9-18.5]cm;all p<0.001).Age,preoperative penile curvature,penile length,postoperative pain,wound infections,and knot palpation insignificantly affected curvature recurrence.Seventeen patients(73.9%)were very satisfied with their surgical outcomes.Conclusions:Incisionless plication of the tunica albuginea is effective and safe for the correction of IVCPC in adults with high success and patient satisfaction rates.展开更多
据北美比较与国际教育学会网站2017年8月22日消息,近日,北美比较与国际教育学会（CIES）期刊《比较教育评论》（Comparative Education Review）第61卷、第3期刊登了香港大学教育学院教授马克·贝磊（Mark Bray）的文章《学校教育...据北美比较与国际教育学会网站2017年8月22日消息,近日,北美比较与国际教育学会（CIES）期刊《比较教育评论》（Comparative Education Review）第61卷、第3期刊登了香港大学教育学院教授马克·贝磊（Mark Bray）的文章《学校教育与补习教育：全球教育格局的变化及其对比较教育的启示》（Schooling and Its Supplements： Changing Global Patterns and Im-plications for Comparative Education ）. 这篇文章审视了学校教育和补习教育发生变化的本质,并提出了补习教育为全球教育格局变化所带来的挑战.展开更多
Peymnie＇s disease （PD） is most simply referred to as a fibrotic wound-healing disorder of the tunica albuginea. It is both a physically and psychologically devastating disorder that causes penile deformity, curvatu...Peymnie＇s disease （PD） is most simply referred to as a fibrotic wound-healing disorder of the tunica albuginea. It is both a physically and psychologically devastating disorder that causes penile deformity, curvature, hinging, narrowing and shortening, which may compromise sexual function. Although a variety of non-surgical treatments have been suggested, none to date offer a reliable and effective correction of the penile deformity. As a result, surgery remains the gold standard treatment option, offering the most rapid and reliable treatment which will be the focus of this article. We review the preoperative evaluation, surgical algorithm, graft materials and postoperative management of PD. Outcomes for tunical shortening, tunical lengthening and penile prosthesis placement for penile straightening are reviewed. Tunica albuginea plication is the preferred method of straightening for men with adequate rigidity and less severe disease defined as curvature less than 70° without narrowing/hinging. Men who have more severe, complex deformity, but maintain strong preoperative erectile function should be considered candidates for straightening with plaque incision or partial excision and grafting. Finally, for those men who have inadequate rigidity and PD, penile prosthesis placement with straightening is the best approach to address both problems.展开更多
Surgical correction can be considered for treating patients with a chronic phase of Peyronie’s disease(PD)and persistent penile curvature.In clinical practice,some patients pay too much attention to surgical complica...Surgical correction can be considered for treating patients with a chronic phase of Peyronie’s disease(PD)and persistent penile curvature.In clinical practice,some patients pay too much attention to surgical complications and refuse the recommended feasible surgical types.Meanwhile,they require operations according to their preferences.This study aimed to evaluate the effects of patients’own choice of surgical type on postoperative satisfaction.This retrospective study analyzed data from 108 patients with PD who underwent surgical correction according to doctors’recommendations or patients’own demands.The objective and subjective surgical outcomes were assessed.Patients1 understanding of the disease was analyzed using a questionnaire survey.Objective measurements of surgical outcomes,including penile straightening,penile length,and sexual function,in patients who received the recommended surgery,were similar to those in patients who did not accept the recommended surgery.However,subjective evaluations,including erectile pain,discomfort because of nodules on the penis,and decreased sensitivity in the penis,were more obvious in patients who did not follow doctors’recommendations.In addition,a questionnaire survey showed that understanding PD and the purpose of surgery of patients who did not follow doctors’advice were inappropriate,as they did not conform to the principle of treatment.The present study showed that surgical correction seemed to be an objectively effective option in the management of patients in the stable chronic phase of PD.Low patient satisfaction might be related to patients’lack of correct understanding of the disease and its treatment strategy as well as unrealistic expectations.展开更多
<strong>Objective:</strong> <span style="font-family:""><span style="font-family:Verdana;">We introduced two novel hemostatic techniques to achieve hemostasis for postp...<strong>Objective:</strong> <span style="font-family:""><span style="font-family:Verdana;">We introduced two novel hemostatic techniques to achieve hemostasis for postpartum hemorrhage (PPH). The first one (A: Uterus Isthmic Plication) was a new uterine compression suture, which compresses the hysterotomy site. In a severe case, we further added vessel ligation suture after </span><span style="font-family:Verdana;">performing A-suture (B-combination suture: B-suture: A + Wide Lateral Uterine </span><span style="font-family:Verdana;">Vascular Ligation). </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Of 140 PPH cases, 90 were with mild PPH and 40 were with severe PPH. Our policy was: perform A-suture to mild PPH and perform B (combination) to severe PPH. Study was performed during 2018-2019. The primary endpoint to evaluate the efficacy of the</span><span><span style="font-family:Verdana;"> procedures was preserving the uterus (no hysterectomy). </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A-procedure,</span></span><span style="font-family:Verdana;"> performed to 90 patients with mild PPH, was effective to all 90 patients, with all preserving the uterus. B-procedure, performed 38 patients with severe PPH (excluding two patients with uterine rupture), was effective in 37 patients, with one having undergone hysterectomy due to coagulopathy. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Uterus Isthmic Plication (A-procedure) and addition of Wide Lateral Uterine Vascular Ligation to procedure-A (B-procedure) achieved hemostasis in patients with PPH. Prospective study is necessary to confirm the present data.</span></span>展开更多
A novel miniature Fabry-Perot interferometric(FPI) temperature sensor is proposed and demonstrated experimentally. The modal interferometer is fabricated by just splicing a section of photonic crystal fiber(PCF) with ...A novel miniature Fabry-Perot interferometric(FPI) temperature sensor is proposed and demonstrated experimentally. The modal interferometer is fabricated by just splicing a section of photonic crystal fiber(PCF) with a single-mode fiber(SMF). The air holes of the PCF are fully collapsed by the discharge arc during the splicing procedure to enhance the reflection coefficient of the splicing point. The transmission spectra with different temperatures are measured, and the experimental results show that the linear response of 11.12 pm/°C in the range of 30–80 °C is obtained. This sensor has potential applications in temperature measurement field.展开更多
It has long been customary since an-cient times to term all the books herbology(Ben Cao Xue),books that record theorigin,sources,collection,preparation,ap-plication effects and other special knowledgeof Chinese herbal...It has long been customary since an-cient times to term all the books herbology(Ben Cao Xue),books that record theorigin,sources,collection,preparation,ap-plication effects and other special knowledgeof Chinese herbal drugs.Herbology means,as a matter of fact,the same as what展开更多
IntroductionFor a practical clectromagnetic boundary value problem(BVP),there are three impor-tant steps in theoretical research:**Formulation of the mathematical models,*Choice and operation of solving method,*Mathem...IntroductionFor a practical clectromagnetic boundary value problem(BVP),there are three impor-tant steps in theoretical research:**Formulation of the mathematical models,*Choice and operation of solving method,*Mathematical skill process,where the second step always makes one difficult,since so many miscellancous methodsappear in various publications,they were proposed and developed by different persons ofdifferent affiliations in different ages,and under different backgrounds of professional ap-plication.展开更多
文摘Aim: To determine the long-term outcome, effectiveness and patient satisfaction of congenital penile curvature correction by plication of tunica albuginea. Methods: From January 1992 to January 2002, 106 young patients underwent surgical correction of congenital penile curvature by corporeal plication. Indications for operation were difficult or impossible vaginal penetration and cosmetic problems. The technique of corporeal plication consists of placing longitudinal plication sutures of 2-zero braided polyester on the convex side of the curvature until the curvature is corrected when erection is artificially induced. Results of this procedure were obtained by retrospective chart reviews and questionnaires via mail. Long-term follow-up ranged from 11 to 132 (mean 69.3) months and data were available for 68 patients. Results: Penile straightening was excellent in 62 patients (91 %) and good with less than 15 degree of residual curvature in 6 patients (9 %). Sixty-seven patients reported no change in erectile rigidity or maintenance postoperatively, while 1 described early detumescence. Shortening of the penis without functional problems was noted by 26 patients (38 %). Thirty-Five patients (51 %) reported feeling palpable indurations (suture knots) on the penis. Temporary numbness of glans penis was described in 3 patients. Overall, 60 patients were very satisfied, 6 satisfied, 2 unsatisfied. Conclusion: Corporeal plication is an effective and durable procedure with a high rate of patient satisfaction.
基金supported by thegrant from the National Natural Science Foundation of China(No.81970656)。
文摘General recommendations regarding surgical techniques are not always appropriate for all Peyronie’s disease(PD)patients.Therefore,the purpose of this study was to investigate the effects of plication procedures in PD patients with severe penile curvature and the effects of early surgical correction in patients who no longer have progressive deformities.The clinical data from 72 patients who underwent plication procedures were analyzed in this study.Patients were divided into Groups A and B according to the curvature severity(≤60°or>60°)and Groups 1 and 2 according to the duration of disease stabilization(≥3 months or<3 months).At the 1-year follow-up,90.0%(36/40)and 90.6%(29/32)patients reported complete penile straightening,and 60.0%(24/40)and 100.0%(32/32)patients reported penile shortening in Groups A and B,respectively.No curvature recurrence occurred in any patient,and no significant differences were observed in postoperative International Index of Erectile Function–Erectile Function domain(IIEF-EF),erectile pain,sensitivity,or suture knots on the penis whether such outcomes were grouped according to the curvature severity or the duration of stabilization.However,the duration from symptom onset to surgical management in Group 1 was significantly longer than that in Group 2(mean±standard deviation[s.d.]:20.9±2.0 months and 14.3±1.2 months,respectively,P<0.001).The present study showed that the plication procedures seemed to be an effective choice for the surgical treatment of PD patients with severe penile curvature.In addition,the early surgical treatment seemed to benefit those patients who already had no erectile pain and no longer exhibited progressive deformity.
文摘The present objective is to observe the side effects and complications of fem ale tubalsterilization by phenol-atabrinepaste (PAP) and phenolm ucilage (PM). 1 705 eligible w om en w ere divided random ly into tw o groups, 871 usinig PAP and 834 w om en using PM. Results: Thefeverratesw ere8.0and 4.4( P< 0.01 ) respec- tively in group PAP and group PM. Infection rates of the appendages w ere 2.3 and 1.2 respectively. The incidence of chem ical peritonitis, w ithin the lim its of pelvic cavity, w ere 1.1and 2.4respectively. Perforation of uterus, pelvic ab- scessand ectopicpregnancy w ere notfound during thisobservation. Slightabdom inal pain after the proceduresw ere 33.6and 30.8respectively. Slightvaginalbleed- ing after the procedure w as 23.2 and 18.0 respectively. Menstruation of the w om en w as not affected by the instillation. This five-year follow -up study neither show ed a positivePap testnor a potentialdeseasecaused by thesterilizing agents. This technique isa safe and efficientm ethod for fem ale sterilization.
文摘Objective: This study seeks to evaluate the results of surgery performed according to the etiological causes of diaphragmatic eventration or paralysis. Method: Files of 54 patients (35 males, 19 females;mean age: 39.1 ± 3.01 years) who had undergone diaphragm plication between January 2005 and June 2011 in two clinics located in Istanbul were studied in terms of pulmonary spirometry, applied surgical procedure, duration of hospitalization, morbidity, and mortality. Results: In diaphragm plications, observed etiologies were isolated diaphragmatic eventration without phrenic nerve injury (Group 1) in 20 (37%) patients due to blunt thoracic trauma;Group 2 (thymoma in 19 (35.2%) patients;lung cancer in 7 (12.9%) patients;mediastinal tumor in 3 (5.6%) patients) and congenital heart surgery (Group 3) in 5 (9.3%) patients. The mean time to plication was 7.4 months in Group 1. The mean duration of hospitalization was 4 days in Group 1, 6.2 days in Group 2, 11.8 days in Group 3. Mean forced vital capacity, forced expiratory volume at 1 second improved by 17%, 20.3%, respectively (p In Group 1, mean dyspnea-related hospital admission before plication was 2.4 times. At the end of 6 months after plication mean dyspnea-related hospital admission was 0 time. All of them returned to daily activities or their job within 6 months in Group 1. Postoperative mortality was observed in 2 (3.7%) patients in Group 3 while the overall complication rates were 24%. The morbidity rates were 8%, 27.5%, 60%, respectively;and the mortality rates were 0%, 0%, 40%, respectively. Conclusion: As a result, it could be suggested that early and timely performed plications for diaphragmatic eventration improves functional status and assesses a shorter lenght of stay. On the other hand,simultaneously performed plications in intraoperative phrenic nerve resections can be performed with acceptable morbidity and no mortality. In diaphragmatic paralysis due to congenital heart surgery, morbidity and mortality rate is still high.
文摘Point-through-point acupuncture is atechnique in which a long needle is insertedin various directions and depths and acts ontwo or more points in treating disease.It iscommonly used in clinical practice.The ap-plication of point-through-point acupunc-ture and its effects are summarized as fol-lows.
文摘Surgical ventricular restoration (SVR) procedures have been developed;however, their long-term effectiveness remains controversial. Although a series of endoventricular spiral plication (ESP) has been rarely reported and its long prognosis is still unknown;this method has a unique concept of left ventricular (LV) restoration without artificial patch materials. Here, we describe the case of a patient with ischemic cardiomyopathy and ischemic mitral regurgitation who successfully underwent ESP, mitral valve repair, and coronary artery bypass grafting. ESP was effective in papillary muscle approximation for avoiding heart failure;however, the noted improvement of LV wall thickening might be temporary.
文摘Diaphragm eventration or paralysis causes elevation of the ipsilateral diaphragm. Some patients have symptoms. The most common symptom is dyspnea. In symptomatic patients with unilateral diaphragm paralysis and dyspnea disproportionate to the degree of physical activity, diaphragm plication is the treatment of choice to relieve dyspnea. We report on our experience with laparoscopic plication of a paralysed hemidiaphragm. The laparoscopic approach is an attractive surgical alternative for the treatment of phrenic nerve palsy. This technique combines the advantage of an excellent field of vision during surgery with a fast postoperative recovery and early discharge from hospital. In accordance to recent literature, we have successfully applied the laparoscopic approach to treat our patients who suffered from a unilateral paralysis of the diaphragm. Preoperative symptoms of exertional dyspnea and orthopnea were significantly reduced.
文摘Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.
文摘Phrenic nerve injury can occur as a complication of lung transplantation. A 54-year-old man underwent single-lung transplantation due to interstitial pneumonia. The patient required circulatory support with venoarterial extracorporeal membrane oxygenation and was unable to be weaned from ventilatory support with nitric oxide. Although enhanced CT scanning showed stenotic anastomosis of the right pulmonary artery (PA), pulmonary angiograph findings revealed that PA flow was normal under sedation and considerably decreased with spontaneous breathing. Fluoroscopy showed that the right diaphragm moved inversely to the position of the left diaphragm, indicating that the right phrenic nerve was paralytic. We performed diaphragmatic plication 7 days after lung transplantation and weaning from ventilator support was accomplished soon thereafter. Phrenic nerve dysfunction is an important clinical problem following lung transplantation. In the present case, diaphragmatic plication was effective for treatment of circulatory failure due to phrenic nerve paralysis even in acute phase after lung transplantation.
文摘Background:In this study,we aimed to evaluate the efficacy of dorsal plication(DP)in correcting mild-to-moderate ventral penile cur-vature(VPC)during primary hypospadias repair with urethral plate preservation.Materials and methods:We retrospectively reviewed medical records of patients who underwent DP during primary hypospadias re-pair with urethral plate preservation between January 2018 and December 2021.Patients were categorized into 2 groups based on the degree of curvature following degloving:<30°(group 1)and 30°to 40°(group 2).Recurrent VPC,urethral complications,and pediatric penile perception scores were analyzed.Results:Seventy-six patients met the inclusion criteria:59 in group 1 and 17 in group 2.The incidences of recurrent VPC(1.7%vs.5.9%;p=0.928)and urethral complications(32.2%vs.29.4%;p=0.827)were comparable between groups.A total of 29 completed pediatric penile perception scores questionnaires were collected.No significant difference was observed in dissatisfaction with penile length(13.6%vs.14.3%;p=0.692).Conclusions:Dorsal plication did not increase the rates of VPC recurrence,urethral complications,or dissatisfaction with penile length in cases with 30°to 40°VPC after degloving.Long-term follow-up with larger sample sizes is warranted to further assess the efficacy of DP.
文摘With the support by the National Natural Science Foundation of China through the Collaborative Innovation Center of Chemistry for Energy Materials,and Qian-ren fund from the University of Science and Technology of China,the research team led by Prof.Zeng Xiaocheng(曾晓成)at the University of Science and Technology of China and the University of Nebraska-Lincoln,cooperated with the research team
文摘Objective To detect the plasma concentration of OLC1(overexpressed in lung cancer 1)protein as a potential cancer biomarker,and evaluating its clinical application value in the diagnosis of non-small cell lung cancer(NSCLC).Methods We prepared OLC1 antibody with OLC1 full length protein,in 5-6-week old Bal B/c mice.Each mouse was immunized four times at a dose
文摘Background:Numerous surgical techniques are available for the correction of isolated ventral congenital penile curvature(IVCPC).This study aimed to assess the outcomes and predictors of IVCPC treatment in adults using an incisionless plication technique.Materials and methods:This prospective case series examined patients with IVCPC who were treated in our hospital between October 2017 and February 2020 using incisionless plication of the tunica albuginea(Essed-Schroeder technique)with a covering pair of absorbable sutures.The primary outcomes were successful correction(defined as a residual curvature≤15 degrees)and patient satisfaction.Postoperative follow-ups were performed at 3,6,and 12 months.Results:A total of 23 patients were treated for IVCPC with a mean(range)age of 25.3(18-31)years.Eighteen patients(78.3%)were single with cosmetic complaints,whereas the other 5 patients(21.7%)were married and presented with a difficult vaginal intromission.The mean(range)curvature,length,and operative time were 40(30-50)degrees,15(10-19)cm,and 82(65-100)minutes,respectively.Postoperative penile pain and numbness occurred in 13 patients(56.5%)and 7 patients(30.4%)only within the first month,respectively.Palpable suture knots were reported in 15 patients(65.5%)without being bothersome up to 12 months.The postoperative means(ranges)of penile curvature and length were significantly different from that of the preoperative values at 3(5[0-20]degrees and 14.5[9-18.5]cm),6(5[0-20]degrees and 14.5[9-18.5]cm),and 12 months(5[0-30]degrees and 14.5[9-18.5]cm;all p<0.001).Age,preoperative penile curvature,penile length,postoperative pain,wound infections,and knot palpation insignificantly affected curvature recurrence.Seventeen patients(73.9%)were very satisfied with their surgical outcomes.Conclusions:Incisionless plication of the tunica albuginea is effective and safe for the correction of IVCPC in adults with high success and patient satisfaction rates.
文摘据北美比较与国际教育学会网站2017年8月22日消息,近日,北美比较与国际教育学会（CIES）期刊《比较教育评论》（Comparative Education Review）第61卷、第3期刊登了香港大学教育学院教授马克·贝磊（Mark Bray）的文章《学校教育与补习教育：全球教育格局的变化及其对比较教育的启示》（Schooling and Its Supplements： Changing Global Patterns and Im-plications for Comparative Education ）. 这篇文章审视了学校教育和补习教育发生变化的本质,并提出了补习教育为全球教育格局变化所带来的挑战.
文摘Peymnie＇s disease （PD） is most simply referred to as a fibrotic wound-healing disorder of the tunica albuginea. It is both a physically and psychologically devastating disorder that causes penile deformity, curvature, hinging, narrowing and shortening, which may compromise sexual function. Although a variety of non-surgical treatments have been suggested, none to date offer a reliable and effective correction of the penile deformity. As a result, surgery remains the gold standard treatment option, offering the most rapid and reliable treatment which will be the focus of this article. We review the preoperative evaluation, surgical algorithm, graft materials and postoperative management of PD. Outcomes for tunical shortening, tunical lengthening and penile prosthesis placement for penile straightening are reviewed. Tunica albuginea plication is the preferred method of straightening for men with adequate rigidity and less severe disease defined as curvature less than 70° without narrowing/hinging. Men who have more severe, complex deformity, but maintain strong preoperative erectile function should be considered candidates for straightening with plaque incision or partial excision and grafting. Finally, for those men who have inadequate rigidity and PD, penile prosthesis placement with straightening is the best approach to address both problems.
基金the National Natural Science Foundation of China(No.81700582)Shanghai Jiaotong University School of Medicine Multi-center Clinical Research Project(DLY201809)Program for outstanding academic leader of Huangpu District.
文摘Surgical correction can be considered for treating patients with a chronic phase of Peyronie’s disease(PD)and persistent penile curvature.In clinical practice,some patients pay too much attention to surgical complications and refuse the recommended feasible surgical types.Meanwhile,they require operations according to their preferences.This study aimed to evaluate the effects of patients’own choice of surgical type on postoperative satisfaction.This retrospective study analyzed data from 108 patients with PD who underwent surgical correction according to doctors’recommendations or patients’own demands.The objective and subjective surgical outcomes were assessed.Patients1 understanding of the disease was analyzed using a questionnaire survey.Objective measurements of surgical outcomes,including penile straightening,penile length,and sexual function,in patients who received the recommended surgery,were similar to those in patients who did not accept the recommended surgery.However,subjective evaluations,including erectile pain,discomfort because of nodules on the penis,and decreased sensitivity in the penis,were more obvious in patients who did not follow doctors’recommendations.In addition,a questionnaire survey showed that understanding PD and the purpose of surgery of patients who did not follow doctors’advice were inappropriate,as they did not conform to the principle of treatment.The present study showed that surgical correction seemed to be an objectively effective option in the management of patients in the stable chronic phase of PD.Low patient satisfaction might be related to patients’lack of correct understanding of the disease and its treatment strategy as well as unrealistic expectations.
文摘<strong>Objective:</strong> <span style="font-family:""><span style="font-family:Verdana;">We introduced two novel hemostatic techniques to achieve hemostasis for postpartum hemorrhage (PPH). The first one (A: Uterus Isthmic Plication) was a new uterine compression suture, which compresses the hysterotomy site. In a severe case, we further added vessel ligation suture after </span><span style="font-family:Verdana;">performing A-suture (B-combination suture: B-suture: A + Wide Lateral Uterine </span><span style="font-family:Verdana;">Vascular Ligation). </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Of 140 PPH cases, 90 were with mild PPH and 40 were with severe PPH. Our policy was: perform A-suture to mild PPH and perform B (combination) to severe PPH. Study was performed during 2018-2019. The primary endpoint to evaluate the efficacy of the</span><span><span style="font-family:Verdana;"> procedures was preserving the uterus (no hysterectomy). </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> A-procedure,</span></span><span style="font-family:Verdana;"> performed to 90 patients with mild PPH, was effective to all 90 patients, with all preserving the uterus. B-procedure, performed 38 patients with severe PPH (excluding two patients with uterine rupture), was effective in 37 patients, with one having undergone hysterectomy due to coagulopathy. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Uterus Isthmic Plication (A-procedure) and addition of Wide Lateral Uterine Vascular Ligation to procedure-A (B-procedure) achieved hemostasis in patients with PPH. Prospective study is necessary to confirm the present data.</span></span>
基金supported by the National Natural Science Foundation of China(Nos.61205068 and 61475133)the College Youth Talent Project of Hebei Province(No.BJ2014057)"Xin Rui Gong Cheng"Talent Project and the Excellent Youth Funds for School of Information Science and Engineering in Yanshan University(No.2014201)
文摘A novel miniature Fabry-Perot interferometric(FPI) temperature sensor is proposed and demonstrated experimentally. The modal interferometer is fabricated by just splicing a section of photonic crystal fiber(PCF) with a single-mode fiber(SMF). The air holes of the PCF are fully collapsed by the discharge arc during the splicing procedure to enhance the reflection coefficient of the splicing point. The transmission spectra with different temperatures are measured, and the experimental results show that the linear response of 11.12 pm/°C in the range of 30–80 °C is obtained. This sensor has potential applications in temperature measurement field.
文摘It has long been customary since an-cient times to term all the books herbology(Ben Cao Xue),books that record theorigin,sources,collection,preparation,ap-plication effects and other special knowledgeof Chinese herbal drugs.Herbology means,as a matter of fact,the same as what
文摘IntroductionFor a practical clectromagnetic boundary value problem(BVP),there are three impor-tant steps in theoretical research:**Formulation of the mathematical models,*Choice and operation of solving method,*Mathematical skill process,where the second step always makes one difficult,since so many miscellancous methodsappear in various publications,they were proposed and developed by different persons ofdifferent affiliations in different ages,and under different backgrounds of professional ap-plication.
