In order to consider the influence of temperature and underground water movement, an elastoplastic model and a 2D FEM stress fields on the migration of radioactive nuclide with code for analysis of coupled thermo-hyd...In order to consider the influence of temperature and underground water movement, an elastoplastic model and a 2D FEM stress fields on the migration of radioactive nuclide with code for analysis of coupled thermo-hydro-mechanical （THM） processes in saturated and unsaturated porous media were extended and improved through introducing the percolation and migration equation, so that the code can be used for solving the temperature field, flow field, stress field and nuclide concentration field simultaneously. The states of temperatures, pore pressures and nuclide concentrations in the near field of a hypothetical nuclear waste repository were investigated. The influence of the half life of the radioactive nuclide on the temporal change of nuclide concentration was analyzed considering the thermo-hydro-mechanical-migratory coupling. The results show that, at the boundary of the vitrified waste, the concentration of radioactive nuclide with a half life of 10 a falls after a period of rising, with the maximum value of 0.182 mol/m3 and the minimum value of 0.181 mol/m^3 at the end of computation. For a half life of 1 000 a, the concentration of radioactive nuclide always increases with the increase of the time during the computation period; and the maximum value is 1.686 mol/m^3 at the end of the computation. Therefore, under the condition of THM coupling, the concentration of radioactive nuclide with a shorter half life will decrease more quickly with water flow; but for the radioactive nuclide with a longer half life, its concentration will keep at a higher level for a longer time in the migration process.展开更多
X-ray imaging is the conventional method for diagnosing the orthopedic condition of a patient. Computerized Tomography(CT) scanning is another diagnostic method that provides patient’s 3D anatomical information. Howe...X-ray imaging is the conventional method for diagnosing the orthopedic condition of a patient. Computerized Tomography(CT) scanning is another diagnostic method that provides patient’s 3D anatomical information. However, both methods have limitations when diagnosing the whole leg; X-ray imaging does not provide 3D information, and normal CT scanning cannot be performed with a standing posture. Obtaining 3D data regarding the whole leg in a standing posture is clinically important because it enables 3D analysis in the weight bearing condition.Based on these clinical needs, a hardware-based bi-plane X-ray imaging system has been developed; it uses two orthogonal X-ray images. However, such methods have not been made available in general clinics because of the hight cost. Therefore, we proposed a widely adaptive method for 2 D X-ray image and 3D CT scan data. By this method, it is possible to threedimensionally analyze the whole leg in standing posture. The optimal position that generates the most similar image is the captured X-ray image. The algorithm verifies the similarity using the performance of the proposed method by simulation-based experiments. Then, we analyzed the internal-external rotation angle of the femur using real patient data. Approximately 10.55 degrees of internal rotations were found relative to the defined anterior-posterior direction. In this paper, we present a useful registration method using the conventional X-ray image and 3D CT scan data to analyze the whole leg in the weight-bearing condition.展开更多
This paper deals with the iterative learning control （ILC） design for multiple-input multiple-output （MIMO）,time-delay systems （TDS）.Two feedback ILC schemes are considered using the so-called two-dimensional ...This paper deals with the iterative learning control （ILC） design for multiple-input multiple-output （MIMO）,time-delay systems （TDS）.Two feedback ILC schemes are considered using the so-called two-dimensional （2D） analysis approach.It shows that continuous-discrete 2D Roesser systems can be developed to describe the entire learning dynamics of both ILC schemes,based on which necessary and sufficient conditions for their stability can be provided.A numerical example is included to validate the theoretical analysis.展开更多
A new method creating depth information for 2D/3D conversion was proposed. The distance between objects is determined by the distances between objects and light source position which is estimated by the analysis of th...A new method creating depth information for 2D/3D conversion was proposed. The distance between objects is determined by the distances between objects and light source position which is estimated by the analysis of the image. The estimated lighting value is used to normalize the image. A threshold value is determined by some weighted operation between the original image and the normalized image. By applying the threshold value to the original image, background area is removed. Depth information of interested area is calculated from the lighting changes. The final 3D images converted with the proposed method are used to verify its effectiveness.展开更多
Genetic divergence was studied in selected 36 genotypes of Dalbergia sissoo Roxb. on the basis of seven morphological parameters. The divergence among genotypes was estimated by Mahalanobis method and genotypes were g...Genetic divergence was studied in selected 36 genotypes of Dalbergia sissoo Roxb. on the basis of seven morphological parameters. The divergence among genotypes was estimated by Mahalanobis method and genotypes were grouped into clusters by Tocher＇s method. All the genotypes were classified into seven distinct clusters on the basis of seven morphological traits. Cluster 1 was the largest with 25 genotypes followed by Cluster 2 （four genotypes）. Cluster 3, 5, 6 and 7 were the divergent clusters. The D2 analysis revealed that D2 value （39.42） between clone 5040 and clone 201 was recorded maximum. The intra-cluster distance ranged from 0.00 （Cluster 3, 5, 6 and 7） to 3.89 （Cluster 1）, the Cluster 3 （clone 33） was the most divergent cluster with maximum inter cluster distance （13.97） with the Cluster 7. By the divergence analysis, the parents for hybridization from diverse clusters could be selected for heterotic hybrids.展开更多
A simple method is proposed, for incremental static analysis of a set of inter-colliding particles, simulating 2D flow. Within each step of proposed algorithm, the particles perform small displacements, proportional t...A simple method is proposed, for incremental static analysis of a set of inter-colliding particles, simulating 2D flow. Within each step of proposed algorithm, the particles perform small displacements, proportional to the out-of-balance forces, acting on them. Numerical experiments show that if the liquid is confined within boundaries of a set of inter-communicating vessels, then the proposed method converges to a final equilibrium state. This incremental static analysis approximates dynamic behavior with strong damping and can provide information, as a first approximation to 2D movement of a liquid. In the initial arrangement of particles, a rhombic element is proposed, which assures satisfactory incompressibility of the fluid. Based on the proposed algorithm, a simple and short computer program (a “pocket” program) has been developed, with only about 120 Fortran instructions. This program is first applied to an amount of liquid, contained in a single vessel. A coarse and refined discretization is tried. In final equilibrium state of liquid, the distribution on hydro-static pressure on vessel boundaries, obtained by proposed computational model, is found in satisfactory approximation with corresponding theoretical data. Then, an opening is formed, at the bottom of a vertical boundary of initial vessel, and the liquid is allowed to flow gradually to an adjacent vessel. Almost whole amount of liquid is transferred, from first to second vessel, except of few drops-particles, which remain, in equilibrium, at the bottom of initial vessel. In the final equilibrium state of liquid, in the second vessel, the free surface level of the liquid confirms that the proposed rhombing element assures a satisfactory incompressibility of the fluid.展开更多
By using Richardson extrapolation and fourth-order compact finite difference scheme on different scale grids, a sixth-order solution is computed on the coarse grid. Other three techniques are applied to obtain a sixth...By using Richardson extrapolation and fourth-order compact finite difference scheme on different scale grids, a sixth-order solution is computed on the coarse grid. Other three techniques are applied to obtain a sixth-order solution on the fine grid, and thus give out three kinds of Richardson extrapolation-based sixth order compact computation methods. By carefully analyzing the truncation errors respectively on 2D Poisson equation, we compare the accuracy of these three sixth order methods theoretically. Numerical results for two test problems are discussed.展开更多
Understanding metal accumulation at organ level in roots, leaves and seeds in O. glaberrima (OG) is crucial for improving physiological and metabolic aspects in growing Asian and African rice in salted areas. The micr...Understanding metal accumulation at organ level in roots, leaves and seeds in O. glaberrima (OG) is crucial for improving physiological and metabolic aspects in growing Asian and African rice in salted areas. The micro-analytical imaging techniques are required to reveal its accumulation and distribution within plant tissues. PIXE studies have been performed to determine different elements in rice plants. The existing microbeam analytical technique at the iThemba LABS will be applied for the 2D image mapping of fresh rice tissues to perform a concentration of low atomic mass elements (such as Al, Si, P, S, Cl, Ca, Ti, Mn, Fe, Cu, Br, Zn and K) with detection limits of typically 1-10 μg/g. Comparison of the distribution of the elements between leaves, root and seed samples using uptake and distribution of elements in particular environmental conditions with potential amount of salt in water have been performed. We are also expecting to indicate metal exclusion as salt tolerance strategies from leaves, root, and seed compartments using matrix correlation between samples and between elements on rice species.展开更多
BACKGROUND The objective of the current study was to elucidate the clinical mechanism through which phospholipase D2(PLD2)exerted a regulatory effect on neutrophil migra-tion,thereby alleviating the progression of acu...BACKGROUND The objective of the current study was to elucidate the clinical mechanism through which phospholipase D2(PLD2)exerted a regulatory effect on neutrophil migra-tion,thereby alleviating the progression of acute pancreatitis.AIM To elucidate the clinical mechanism through which PLD2 exerted a regulatory effect on neutrophil migration,thereby alleviating the progression of acute pan-creatitis.METHODS The study involved 90 patients diagnosed with acute pancreatitis,admitted to our hospital between March 2020 and November 2022.A retrospective analysis was conducted,categorizing patients based on Ranson score severity into mild(n=25),moderate(n=30),and severe(n=35)groups.Relevant data was collected for each group.Western blot analysis assessed PLD2 protein expression in patient serum.Real-time reverse transcription polymerase chain reaction was used to evaluate the mRNA expression of chemokine receptors associated with neutrophil migration.Serum levels of inflammatory factors in patients were detected using enzyme-linked immunosorbent assay.Transwell migration tests were conducted to compare migration of neutrophils across groups and analyze the influence of PLD2 on neutrophil migration.RESULTS Overall data analysis did not find significant differences between patient groups(P>0.05).The expression of PLD2 protein in the severe group was lower than that in the moderate and mild groups(P<0.05).The expression level of PLD2 in the moderate group was also lower than that in the mild group(P<0.05).The severity of acute pancreatitis is negatively correlated with PLD2 expression(r=-0.75,P=0.002).The mRNA levels of C-X-C chemokine receptor type 1,C-X-C chemokine receptor type 2,C-C chemokine receptor type 2,and C-C chemokine receptor type 5 in the severe group are significantly higher than those in the moderate and mild groups(P<0.05),and the expression levels in the moderate group are also higher than those in the mild group(P<0.05).The levels of C-reactive protein,tumor necrosis factor-α,interleukin-1β,and interleukin-6 in the severe group were higher than those in the moderate and mild groups(P<0.05),and the levels in the moderate group were also higher than those in the mild group(P<0.05).The number of migrating neutrophils in the severe group was higher than that in the moderate and mild groups(P<0.05),and the moderate group was also higher than the mild group(P<0.05).In addition,the number of migrating neutrophils in the mild group combined with PLD2 inhibitor was higher than that in the mild group(P<0.05),and the number of migrating neutrophils in the moderate group combined with PLD2 inhibitor was higher than that in the moderate group(P<0.05).The number of migrating neutrophils in the severe group+PLD2 inhibitor group was significantly higher than that in the severe group(P<0.05),indicating that PLD2 inhibitors significantly stimulated neutrophil migration.CONCLUSION PLD2 exerted a crucial regulatory role in the pathological progression of acute pancreatitis.Its protein expression varied among patients based on the severity of the disease,and a negative correlation existed between PLD2 expression and disease severity.Additionally,PLD2 appeared to impede acute pancreatitis progression by limiting neutrophil migration.展开更多
In order to study the safety factor and instability process of cohesive soil slope, the discrete element method(DEM) was applied. DEM software PFC2 D was used to simulate the triaxial test to study the influence of th...In order to study the safety factor and instability process of cohesive soil slope, the discrete element method(DEM) was applied. DEM software PFC2 D was used to simulate the triaxial test to study the influence of the particle micro parameters on the macroscopic characteristics of cohesive soil and calibrate the micro parameters of DEM model on this basis. Embankment slope stability analysis was carried out by strength reduction and gravity increase method, it is shown that the safety factor obtained by strength reduction method is more conservative, and the arc-shaped feature of the sliding surface under the gravity increase method is more obvious. Throughout the progressive failure process, the failure trends, maximum displacements, and velocity changes obtained by the two methods were consistent. When slope was destroyed, the upper part was cracked, the middle part was sheared, and the lower part was destroyed by extrusion. The conclusions of this paper can be applied to the safety factor calculation of cohesive soil slopes and the analysis of the instability process.展开更多
Understanding the steady mechanism of biomass smoldering plays a great role in the utilization of smoldering technology.In this study numerical analysis of steady smoldering of biomass rods was performed.A two-dimensi...Understanding the steady mechanism of biomass smoldering plays a great role in the utilization of smoldering technology.In this study numerical analysis of steady smoldering of biomass rods was performed.A two-dimensional(2D)steady model taking into account both char oxidation and pyrolysis was developed on the basis of a calculated propagation velocity according to empirical correlation.The model was validated against the smoldering experiment of biomass rods under natural conditions,and the maximum error was smaller than 31%.Parameter sensitivity analysis found that propagation velocity decreases significantly while oxidation area and pyrolysis zone increase significantly with the increasing diameter of rod fuel.展开更多
In this study, geophysical and geotechnical studies were carried out in NE Turkey to evaluate the stability and support design of cut slopes that will be excavated during the construction of a new border control compl...In this study, geophysical and geotechnical studies were carried out in NE Turkey to evaluate the stability and support design of cut slopes that will be excavated during the construction of a new border control complex. 13 vertical and 3 inclined boreholes were drilled, and 2D electrical resistivity tomography surveys were conducted along 8 profiles to investigate the horizontal and vertical continuity of the geological units. Strength characteristics of all units were determined by laboratory tests. Limit equilibrium(LE) slope stability analyses were conducted on the geological model for static and pseudo-static conditions and factor of safety values as low as 0.227 were determined for post-excavation. Back analysis was conducted for the determination of required support forces on the slopes to achieve a factor of safety of 1.3. A feasible support system consisting of bored piles and rock anchors was designed based on back analysis results for each cut slope. LE analyses were repeated after the implementation of the designed support systems and the lowest factor of safety value increased to 1.35. The utility and safety of the designed support systems were investigated using finite element slope stability analyses and strength reduction factor values higher than 1.3 were determined which means support systems will function as intended and no support failure will occur. Lastly, quick reference charts were created for alluvium and residual soil materials to easily determine the safe slope angle in the future in case no support measures will be applied.展开更多
The present work aims to determine the geological structure, to highlight and to determine the characteristics of the fault system responsible for the current structure of the study area through the interpretation of ...The present work aims to determine the geological structure, to highlight and to determine the characteristics of the fault system responsible for the current structure of the study area through the interpretation of available aeromagnetic data. Total magnetic intensity anomaly (TMI) was critically interpreted using several analysis techniques including Reduction to Equator (RTE), First Vertical Derivative, upward continuation, spectral analysis and 2D3/4 modelling. All results obtained from the interpretation process were combined together to draw an interpretative geological map of the area and allow the general view of the surface and sub-surface structures. The interpretative geological map reveals that the geological formations of the studied area appear to be intensely fractured by an E-W, ENE-WSW and NE-SW main orientation fault system. The lineaments identified in the area study could be linked to the Pan-African orogeny and seem to correspond to deep-seated basement structures, which are referred to the tectonic boundary between Congo Craton and the Pan-African orogeny belt. According to spectral analysis results, the depths of the sources of superficial and deep magnetic anomalies are 2500 m and 12,000 m respectively. The 2D3/4 modelling of one magnetic profile plotted on the reduced residual map at the equator was performed to approximate the geometry and depth of the sources of magnetic anomalies, the model suggests the intrusion of a large body of high susceptibility during the continental collision. The results of this study can be used to better understand deep-seated basement structures and to support decisions with regard to the development of industrial areas, as well as of hydrogeological and/or mining investigations to be undertaken in the study area.展开更多
目的探讨2型糖尿病患者血脂异常与血清维生素D水平的相关性。方法选取2021年2月—2023年2月在运城市盐湖区人民医院就诊的2型糖尿病患者396例为研究对象,根据血脂是否异常分为血脂异常组(n=173)和血脂正常组(n=223),收集患者的年龄、性...目的探讨2型糖尿病患者血脂异常与血清维生素D水平的相关性。方法选取2021年2月—2023年2月在运城市盐湖区人民医院就诊的2型糖尿病患者396例为研究对象,根据血脂是否异常分为血脂异常组(n=173)和血脂正常组(n=223),收集患者的年龄、性别、身体质量指数(body mass index,BMI)及血压等基本资料,测量身高及体质量,检测空腹血糖和血清中25-羟基维生素D_(3)的水平,探索患者血脂异常与血清维生素D水平的相关关系。结果2组患者的性别、BMI及血清25-羟基维生素D_(3)水平差异有统计学意义(P<0.05)。logistics回归分析显示,男性、超重或肥胖及血清25-羟基维生素D_(3)水平不足均为2型糖尿病患者发生血脂异常的独立危险因素(均P<0.05)。结论血清25-羟基维生素D_(3)水平不足是2型糖尿病患者发生血脂异常的独立危险因素之一,临床应重视2型糖尿病患者维生素D水平的监测,以利于早期预防和干预血脂异常。展开更多
Formed on top of the Gulf of Cadiz, the Al Idrissi mud volcano is the shallowest and largest mud volcano in the El Arraiche mud volcano field of the northwestern Moroccan margin. The development and morphology of mud ...Formed on top of the Gulf of Cadiz, the Al Idrissi mud volcano is the shallowest and largest mud volcano in the El Arraiche mud volcano field of the northwestern Moroccan margin. The development and morphology of mud volcanoes from the El Arraiche mud volcanoes group have been studied at a large scale. However, the time interval related to their formation period still needs to be better understood. In this regard, we interpreted and analyzed the seismic facies from the 2D reflection data of the GEOMARGEN-1 campaign, which took place in 2011. The aim was to identify the seismic sequences and draw the Al Idrissi mud volcano system to determine the formation period of the Al Idriss mud volcano. And as a result, the Al Idrissi mud volcano system is made of both buried and superficial bicone and was identified along with the Upper Tortonian to Messinian-Upper Pliocene facies. As the initial mud volcano extrusive edifice, the buried bicone was formed in the Late-Messinian to Early-Pliocene period. However, the superficial bicone, as the final extrusive edifice, was included in the Late Pliocene. In this case, the timing interval between the buried and superficial bicone is equivalent to the Late-Messinian to Upper-Pliocene period. Therefore, the latter corresponds to the Al Idrissi mud volcano formation period.展开更多
One important application of independent component analysis （ICA） is in image processing. A two dimensional （2-D） composite ICA algorithm framework for 2-D image independent component analysis （2-D ICA） is propo...One important application of independent component analysis （ICA） is in image processing. A two dimensional （2-D） composite ICA algorithm framework for 2-D image independent component analysis （2-D ICA） is proposed. The 2-D nature of the algorithm provides it an advantage of circumventing the roundabout transforming procedures between two dimensional （2-D） image deta and one-dimensional （l-D） signal. Moreover the combination of the Newton （fixed-point algorithm） and natural gradient algorithms in this composite algorithm increases its efficiency and robustness. The convincing results of a successful example in functional magnetic resonance imaging （fMRI） show the potential application of composite 2-D ICA in the brain activity detection.展开更多
目的系统评价维生素D补充对2型糖尿病患者的空腹血糖、胰岛素抵抗、胰岛素β细胞功能等指标的影响。方法计算机检索Pub Med、The Cochrane Library(2015年12期)、Web of Science、Science Direct Online、VIP、CNKI、Wan Fang Data和CB...目的系统评价维生素D补充对2型糖尿病患者的空腹血糖、胰岛素抵抗、胰岛素β细胞功能等指标的影响。方法计算机检索Pub Med、The Cochrane Library(2015年12期)、Web of Science、Science Direct Online、VIP、CNKI、Wan Fang Data和CBM数据库,搜集2型糖尿病患者补充维生素D相关的随机对照试验(RCT),检索时限均为从建库到2015年12月。由2位评价员独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Rev Man 5.3和Stata 12.0软件进行Meta分析。结果最终纳入22个RCT,共1 756例患者(试验组889例,对照组867例)。Meta分析结果显示,与对照组相比,维生素D补充组HOMA-IR指标明显改善[SMD=–0.68,95%CI(–1.23,–0.12),P=0.02],但在FPG[MD=–3.64,95%CI(–11.41,4.13),P=0.36]、Hb A1c[MD=–0.04,95%(–0.16,0.09),P=0.55]和HOMA-β[SMD=–0.17,95%CI(–1.39,1.04),P=0.78]方面,两组差异无统计学意义。进一步的亚组分析结果显示,维生素D补充组在中东人群、随访时间≤3个月的FPG水平[中东人:MD=–8.83,95%CI(–15.12,–2.54),P=0.006;随访≤3月:MD=–7.94,95%CI(–13.39,–2.50),P=0.004]和HOMA-IR指标[中东人:SMD=–0.94,95%CI(–1.80,–0.09),P=0.03;随访≤3月SMD=–1.02,95%CI(–1.95,–0.10),P=0.03]方面明显优于对照组。结论当前证据显示,2型糖尿病患者补充维生素D可改善胰岛素抵抗,但对血糖控制和胰岛β细胞功能的影响并不显著。维生素D补充对2型糖尿病患者血糖控制、改善胰岛素抵抗和胰岛β细胞功能的证据尚不充分,仍需大量高质量的研究证实。展开更多
基金Project(2010CB732101) supported by the National Basic Research Program of China Project(SKLQ 008) supported by the Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering of China
文摘In order to consider the influence of temperature and underground water movement, an elastoplastic model and a 2D FEM stress fields on the migration of radioactive nuclide with code for analysis of coupled thermo-hydro-mechanical （THM） processes in saturated and unsaturated porous media were extended and improved through introducing the percolation and migration equation, so that the code can be used for solving the temperature field, flow field, stress field and nuclide concentration field simultaneously. The states of temperatures, pore pressures and nuclide concentrations in the near field of a hypothetical nuclear waste repository were investigated. The influence of the half life of the radioactive nuclide on the temporal change of nuclide concentration was analyzed considering the thermo-hydro-mechanical-migratory coupling. The results show that, at the boundary of the vitrified waste, the concentration of radioactive nuclide with a half life of 10 a falls after a period of rising, with the maximum value of 0.182 mol/m3 and the minimum value of 0.181 mol/m^3 at the end of computation. For a half life of 1 000 a, the concentration of radioactive nuclide always increases with the increase of the time during the computation period; and the maximum value is 1.686 mol/m^3 at the end of the computation. Therefore, under the condition of THM coupling, the concentration of radioactive nuclide with a shorter half life will decrease more quickly with water flow; but for the radioactive nuclide with a longer half life, its concentration will keep at a higher level for a longer time in the migration process.
基金Supported by the KIST institutional program(2E26880,2E26276)
文摘X-ray imaging is the conventional method for diagnosing the orthopedic condition of a patient. Computerized Tomography(CT) scanning is another diagnostic method that provides patient’s 3D anatomical information. However, both methods have limitations when diagnosing the whole leg; X-ray imaging does not provide 3D information, and normal CT scanning cannot be performed with a standing posture. Obtaining 3D data regarding the whole leg in a standing posture is clinically important because it enables 3D analysis in the weight bearing condition.Based on these clinical needs, a hardware-based bi-plane X-ray imaging system has been developed; it uses two orthogonal X-ray images. However, such methods have not been made available in general clinics because of the hight cost. Therefore, we proposed a widely adaptive method for 2 D X-ray image and 3D CT scan data. By this method, it is possible to threedimensionally analyze the whole leg in standing posture. The optimal position that generates the most similar image is the captured X-ray image. The algorithm verifies the similarity using the performance of the proposed method by simulation-based experiments. Then, we analyzed the internal-external rotation angle of the femur using real patient data. Approximately 10.55 degrees of internal rotations were found relative to the defined anterior-posterior direction. In this paper, we present a useful registration method using the conventional X-ray image and 3D CT scan data to analyze the whole leg in the weight-bearing condition.
基金supported by the National Natural Science Foundation of China(No.60727002,60774003,60921001,90916024)the COSTIND(No.A2120061303)the National 973 Program(No.2005CB321902)
文摘This paper deals with the iterative learning control （ILC） design for multiple-input multiple-output （MIMO）,time-delay systems （TDS）.Two feedback ILC schemes are considered using the so-called two-dimensional （2D） analysis approach.It shows that continuous-discrete 2D Roesser systems can be developed to describe the entire learning dynamics of both ILC schemes,based on which necessary and sufficient conditions for their stability can be provided.A numerical example is included to validate the theoretical analysis.
文摘A new method creating depth information for 2D/3D conversion was proposed. The distance between objects is determined by the distances between objects and light source position which is estimated by the analysis of the image. The estimated lighting value is used to normalize the image. A threshold value is determined by some weighted operation between the original image and the normalized image. By applying the threshold value to the original image, background area is removed. Depth information of interested area is calculated from the lighting changes. The final 3D images converted with the proposed method are used to verify its effectiveness.
文摘Genetic divergence was studied in selected 36 genotypes of Dalbergia sissoo Roxb. on the basis of seven morphological parameters. The divergence among genotypes was estimated by Mahalanobis method and genotypes were grouped into clusters by Tocher＇s method. All the genotypes were classified into seven distinct clusters on the basis of seven morphological traits. Cluster 1 was the largest with 25 genotypes followed by Cluster 2 （four genotypes）. Cluster 3, 5, 6 and 7 were the divergent clusters. The D2 analysis revealed that D2 value （39.42） between clone 5040 and clone 201 was recorded maximum. The intra-cluster distance ranged from 0.00 （Cluster 3, 5, 6 and 7） to 3.89 （Cluster 1）, the Cluster 3 （clone 33） was the most divergent cluster with maximum inter cluster distance （13.97） with the Cluster 7. By the divergence analysis, the parents for hybridization from diverse clusters could be selected for heterotic hybrids.
文摘A simple method is proposed, for incremental static analysis of a set of inter-colliding particles, simulating 2D flow. Within each step of proposed algorithm, the particles perform small displacements, proportional to the out-of-balance forces, acting on them. Numerical experiments show that if the liquid is confined within boundaries of a set of inter-communicating vessels, then the proposed method converges to a final equilibrium state. This incremental static analysis approximates dynamic behavior with strong damping and can provide information, as a first approximation to 2D movement of a liquid. In the initial arrangement of particles, a rhombic element is proposed, which assures satisfactory incompressibility of the fluid. Based on the proposed algorithm, a simple and short computer program (a “pocket” program) has been developed, with only about 120 Fortran instructions. This program is first applied to an amount of liquid, contained in a single vessel. A coarse and refined discretization is tried. In final equilibrium state of liquid, the distribution on hydro-static pressure on vessel boundaries, obtained by proposed computational model, is found in satisfactory approximation with corresponding theoretical data. Then, an opening is formed, at the bottom of a vertical boundary of initial vessel, and the liquid is allowed to flow gradually to an adjacent vessel. Almost whole amount of liquid is transferred, from first to second vessel, except of few drops-particles, which remain, in equilibrium, at the bottom of initial vessel. In the final equilibrium state of liquid, in the second vessel, the free surface level of the liquid confirms that the proposed rhombing element assures a satisfactory incompressibility of the fluid.
文摘By using Richardson extrapolation and fourth-order compact finite difference scheme on different scale grids, a sixth-order solution is computed on the coarse grid. Other three techniques are applied to obtain a sixth-order solution on the fine grid, and thus give out three kinds of Richardson extrapolation-based sixth order compact computation methods. By carefully analyzing the truncation errors respectively on 2D Poisson equation, we compare the accuracy of these three sixth order methods theoretically. Numerical results for two test problems are discussed.
文摘Understanding metal accumulation at organ level in roots, leaves and seeds in O. glaberrima (OG) is crucial for improving physiological and metabolic aspects in growing Asian and African rice in salted areas. The micro-analytical imaging techniques are required to reveal its accumulation and distribution within plant tissues. PIXE studies have been performed to determine different elements in rice plants. The existing microbeam analytical technique at the iThemba LABS will be applied for the 2D image mapping of fresh rice tissues to perform a concentration of low atomic mass elements (such as Al, Si, P, S, Cl, Ca, Ti, Mn, Fe, Cu, Br, Zn and K) with detection limits of typically 1-10 μg/g. Comparison of the distribution of the elements between leaves, root and seed samples using uptake and distribution of elements in particular environmental conditions with potential amount of salt in water have been performed. We are also expecting to indicate metal exclusion as salt tolerance strategies from leaves, root, and seed compartments using matrix correlation between samples and between elements on rice species.
文摘BACKGROUND The objective of the current study was to elucidate the clinical mechanism through which phospholipase D2(PLD2)exerted a regulatory effect on neutrophil migra-tion,thereby alleviating the progression of acute pancreatitis.AIM To elucidate the clinical mechanism through which PLD2 exerted a regulatory effect on neutrophil migration,thereby alleviating the progression of acute pan-creatitis.METHODS The study involved 90 patients diagnosed with acute pancreatitis,admitted to our hospital between March 2020 and November 2022.A retrospective analysis was conducted,categorizing patients based on Ranson score severity into mild(n=25),moderate(n=30),and severe(n=35)groups.Relevant data was collected for each group.Western blot analysis assessed PLD2 protein expression in patient serum.Real-time reverse transcription polymerase chain reaction was used to evaluate the mRNA expression of chemokine receptors associated with neutrophil migration.Serum levels of inflammatory factors in patients were detected using enzyme-linked immunosorbent assay.Transwell migration tests were conducted to compare migration of neutrophils across groups and analyze the influence of PLD2 on neutrophil migration.RESULTS Overall data analysis did not find significant differences between patient groups(P>0.05).The expression of PLD2 protein in the severe group was lower than that in the moderate and mild groups(P<0.05).The expression level of PLD2 in the moderate group was also lower than that in the mild group(P<0.05).The severity of acute pancreatitis is negatively correlated with PLD2 expression(r=-0.75,P=0.002).The mRNA levels of C-X-C chemokine receptor type 1,C-X-C chemokine receptor type 2,C-C chemokine receptor type 2,and C-C chemokine receptor type 5 in the severe group are significantly higher than those in the moderate and mild groups(P<0.05),and the expression levels in the moderate group are also higher than those in the mild group(P<0.05).The levels of C-reactive protein,tumor necrosis factor-α,interleukin-1β,and interleukin-6 in the severe group were higher than those in the moderate and mild groups(P<0.05),and the levels in the moderate group were also higher than those in the mild group(P<0.05).The number of migrating neutrophils in the severe group was higher than that in the moderate and mild groups(P<0.05),and the moderate group was also higher than the mild group(P<0.05).In addition,the number of migrating neutrophils in the mild group combined with PLD2 inhibitor was higher than that in the mild group(P<0.05),and the number of migrating neutrophils in the moderate group combined with PLD2 inhibitor was higher than that in the moderate group(P<0.05).The number of migrating neutrophils in the severe group+PLD2 inhibitor group was significantly higher than that in the severe group(P<0.05),indicating that PLD2 inhibitors significantly stimulated neutrophil migration.CONCLUSION PLD2 exerted a crucial regulatory role in the pathological progression of acute pancreatitis.Its protein expression varied among patients based on the severity of the disease,and a negative correlation existed between PLD2 expression and disease severity.Additionally,PLD2 appeared to impede acute pancreatitis progression by limiting neutrophil migration.
基金Project(51808116) supported by the National Natural Science Foundation of ChinaProject(BK20180404) supported by the Natural Science Foundation of Jiangsu Province, China+1 种基金Project(KFJ170106) supported by the Changsha University of Science & Technology via Open Fund of National Engineering Laboratory of Highway Maintenance Technology,ChinaProject(242020R40133) supported by Fundamental Research Funds for the Central Universities, China。
文摘In order to study the safety factor and instability process of cohesive soil slope, the discrete element method(DEM) was applied. DEM software PFC2 D was used to simulate the triaxial test to study the influence of the particle micro parameters on the macroscopic characteristics of cohesive soil and calibrate the micro parameters of DEM model on this basis. Embankment slope stability analysis was carried out by strength reduction and gravity increase method, it is shown that the safety factor obtained by strength reduction method is more conservative, and the arc-shaped feature of the sliding surface under the gravity increase method is more obvious. Throughout the progressive failure process, the failure trends, maximum displacements, and velocity changes obtained by the two methods were consistent. When slope was destroyed, the upper part was cracked, the middle part was sheared, and the lower part was destroyed by extrusion. The conclusions of this paper can be applied to the safety factor calculation of cohesive soil slopes and the analysis of the instability process.
文摘Understanding the steady mechanism of biomass smoldering plays a great role in the utilization of smoldering technology.In this study numerical analysis of steady smoldering of biomass rods was performed.A two-dimensional(2D)steady model taking into account both char oxidation and pyrolysis was developed on the basis of a calculated propagation velocity according to empirical correlation.The model was validated against the smoldering experiment of biomass rods under natural conditions,and the maximum error was smaller than 31%.Parameter sensitivity analysis found that propagation velocity decreases significantly while oxidation area and pyrolysis zone increase significantly with the increasing diameter of rod fuel.
文摘In this study, geophysical and geotechnical studies were carried out in NE Turkey to evaluate the stability and support design of cut slopes that will be excavated during the construction of a new border control complex. 13 vertical and 3 inclined boreholes were drilled, and 2D electrical resistivity tomography surveys were conducted along 8 profiles to investigate the horizontal and vertical continuity of the geological units. Strength characteristics of all units were determined by laboratory tests. Limit equilibrium(LE) slope stability analyses were conducted on the geological model for static and pseudo-static conditions and factor of safety values as low as 0.227 were determined for post-excavation. Back analysis was conducted for the determination of required support forces on the slopes to achieve a factor of safety of 1.3. A feasible support system consisting of bored piles and rock anchors was designed based on back analysis results for each cut slope. LE analyses were repeated after the implementation of the designed support systems and the lowest factor of safety value increased to 1.35. The utility and safety of the designed support systems were investigated using finite element slope stability analyses and strength reduction factor values higher than 1.3 were determined which means support systems will function as intended and no support failure will occur. Lastly, quick reference charts were created for alluvium and residual soil materials to easily determine the safe slope angle in the future in case no support measures will be applied.
文摘The present work aims to determine the geological structure, to highlight and to determine the characteristics of the fault system responsible for the current structure of the study area through the interpretation of available aeromagnetic data. Total magnetic intensity anomaly (TMI) was critically interpreted using several analysis techniques including Reduction to Equator (RTE), First Vertical Derivative, upward continuation, spectral analysis and 2D3/4 modelling. All results obtained from the interpretation process were combined together to draw an interpretative geological map of the area and allow the general view of the surface and sub-surface structures. The interpretative geological map reveals that the geological formations of the studied area appear to be intensely fractured by an E-W, ENE-WSW and NE-SW main orientation fault system. The lineaments identified in the area study could be linked to the Pan-African orogeny and seem to correspond to deep-seated basement structures, which are referred to the tectonic boundary between Congo Craton and the Pan-African orogeny belt. According to spectral analysis results, the depths of the sources of superficial and deep magnetic anomalies are 2500 m and 12,000 m respectively. The 2D3/4 modelling of one magnetic profile plotted on the reduced residual map at the equator was performed to approximate the geometry and depth of the sources of magnetic anomalies, the model suggests the intrusion of a large body of high susceptibility during the continental collision. The results of this study can be used to better understand deep-seated basement structures and to support decisions with regard to the development of industrial areas, as well as of hydrogeological and/or mining investigations to be undertaken in the study area.
文摘目的探讨2型糖尿病患者血脂异常与血清维生素D水平的相关性。方法选取2021年2月—2023年2月在运城市盐湖区人民医院就诊的2型糖尿病患者396例为研究对象,根据血脂是否异常分为血脂异常组(n=173)和血脂正常组(n=223),收集患者的年龄、性别、身体质量指数(body mass index,BMI)及血压等基本资料,测量身高及体质量,检测空腹血糖和血清中25-羟基维生素D_(3)的水平,探索患者血脂异常与血清维生素D水平的相关关系。结果2组患者的性别、BMI及血清25-羟基维生素D_(3)水平差异有统计学意义(P<0.05)。logistics回归分析显示,男性、超重或肥胖及血清25-羟基维生素D_(3)水平不足均为2型糖尿病患者发生血脂异常的独立危险因素(均P<0.05)。结论血清25-羟基维生素D_(3)水平不足是2型糖尿病患者发生血脂异常的独立危险因素之一,临床应重视2型糖尿病患者维生素D水平的监测,以利于早期预防和干预血脂异常。
文摘Formed on top of the Gulf of Cadiz, the Al Idrissi mud volcano is the shallowest and largest mud volcano in the El Arraiche mud volcano field of the northwestern Moroccan margin. The development and morphology of mud volcanoes from the El Arraiche mud volcanoes group have been studied at a large scale. However, the time interval related to their formation period still needs to be better understood. In this regard, we interpreted and analyzed the seismic facies from the 2D reflection data of the GEOMARGEN-1 campaign, which took place in 2011. The aim was to identify the seismic sequences and draw the Al Idrissi mud volcano system to determine the formation period of the Al Idriss mud volcano. And as a result, the Al Idrissi mud volcano system is made of both buried and superficial bicone and was identified along with the Upper Tortonian to Messinian-Upper Pliocene facies. As the initial mud volcano extrusive edifice, the buried bicone was formed in the Late-Messinian to Early-Pliocene period. However, the superficial bicone, as the final extrusive edifice, was included in the Late Pliocene. In this case, the timing interval between the buried and superficial bicone is equivalent to the Late-Messinian to Upper-Pliocene period. Therefore, the latter corresponds to the Al Idrissi mud volcano formation period.
基金Supported by the 973 Project (No.2003CB716106), NSFC (No.90208003, 30200059), TRAPOYT, Doctor Training Fund of MOE, PRC, Key Research Project of Science and Technology of MOE, Fok Ying Tong Education Foundation (No.91041)
文摘One important application of independent component analysis （ICA） is in image processing. A two dimensional （2-D） composite ICA algorithm framework for 2-D image independent component analysis （2-D ICA） is proposed. The 2-D nature of the algorithm provides it an advantage of circumventing the roundabout transforming procedures between two dimensional （2-D） image deta and one-dimensional （l-D） signal. Moreover the combination of the Newton （fixed-point algorithm） and natural gradient algorithms in this composite algorithm increases its efficiency and robustness. The convincing results of a successful example in functional magnetic resonance imaging （fMRI） show the potential application of composite 2-D ICA in the brain activity detection.
文摘目的系统评价维生素D补充对2型糖尿病患者的空腹血糖、胰岛素抵抗、胰岛素β细胞功能等指标的影响。方法计算机检索Pub Med、The Cochrane Library(2015年12期)、Web of Science、Science Direct Online、VIP、CNKI、Wan Fang Data和CBM数据库,搜集2型糖尿病患者补充维生素D相关的随机对照试验(RCT),检索时限均为从建库到2015年12月。由2位评价员独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Rev Man 5.3和Stata 12.0软件进行Meta分析。结果最终纳入22个RCT,共1 756例患者(试验组889例,对照组867例)。Meta分析结果显示,与对照组相比,维生素D补充组HOMA-IR指标明显改善[SMD=–0.68,95%CI(–1.23,–0.12),P=0.02],但在FPG[MD=–3.64,95%CI(–11.41,4.13),P=0.36]、Hb A1c[MD=–0.04,95%(–0.16,0.09),P=0.55]和HOMA-β[SMD=–0.17,95%CI(–1.39,1.04),P=0.78]方面,两组差异无统计学意义。进一步的亚组分析结果显示,维生素D补充组在中东人群、随访时间≤3个月的FPG水平[中东人:MD=–8.83,95%CI(–15.12,–2.54),P=0.006;随访≤3月:MD=–7.94,95%CI(–13.39,–2.50),P=0.004]和HOMA-IR指标[中东人:SMD=–0.94,95%CI(–1.80,–0.09),P=0.03;随访≤3月SMD=–1.02,95%CI(–1.95,–0.10),P=0.03]方面明显优于对照组。结论当前证据显示,2型糖尿病患者补充维生素D可改善胰岛素抵抗,但对血糖控制和胰岛β细胞功能的影响并不显著。维生素D补充对2型糖尿病患者血糖控制、改善胰岛素抵抗和胰岛β细胞功能的证据尚不充分,仍需大量高质量的研究证实。
