Although outstanding power conversion efficiency has been achieved in perovskite solar cells(PSCs),poor stability and lead(Pb)toxicity are still the key challenges limiting the commercial application of PSCs.Herein,we...Although outstanding power conversion efficiency has been achieved in perovskite solar cells(PSCs),poor stability and lead(Pb)toxicity are still the key challenges limiting the commercial application of PSCs.Herein,we adopted both chemical encapsulation and physical encapsulation to address these problems.Via strong chemical interaction between dibutyl phthalate(DBP)and perovskite,the chemical encapsulation strategy results in higher perovskite film quality with reduced trap density,and the device efficiency enhances from 22.07%to 24.36%.Physical encapsulation polymer with high film robustness and self-healing properties could effectively isolate external risks and restore protection after physical damage.Furthermore,both chemical and physical encapsulation materials could trap Pb ions leaking from the perovskite materials by forming coordination interactions.We simulated realistic scenarios in which PSCs encapsulated by different methods suffered water immersion and mechanical damage,and quantitatively measured Pb leakage rates under different conditions.Higher device stability and greater Pb leakage reduction were achieved,confirming the excellent encapsulation effect of the synergy of chemical and physical encapsulation.This study provides an effective strategy to realize safe and environmentally friendly PSCs to promote their commercialization.展开更多
Dendrimers are macromolecules characterized by high controlled size, shape and architecture, presence of inner cavities able to accommodate small molecules and many peripheral functional groups to bind target entities...Dendrimers are macromolecules characterized by high controlled size, shape and architecture, presence of inner cavities able to accommodate small molecules and many peripheral functional groups to bind target entities. They are of eminent interest for biomedical applications, including gene transfection, tissue engineering, imaging, and drug delivery. The well-known pharmacological activities of ursolic and oleanolic acids are limited by their small water solubility, non-specific cell distribution, low bioavailability, poor pharmacokinetics, and their direct administration could result in the release of thrombi. To overcome such problems, in this paper we described their physical incorporation inside amino acids-modified polyester-based dendrimers which made them highly water-soluble. IR, NMR, zeta potential, mean size of particles, buffer capacity and drug release profiles of prepared materials were reported. The achieved water-soluble complexes harmonize a polycationic character and a buffer capacity which presuppose efficient cell penetration and increased residence time with a biodegradable cell respectful scaffold, thus appearing as a promising team of not toxic prodrugs for safe administration of ursolic and oleanolic acids.展开更多
基金This work was financially supported by the National Natural Science Foundation of China(52192610,62374128,62274127,62404169)National Key Research and Development Program of China(Grant 2021YFA0715600,2021YFA0717700)+6 种基金Key Research and Development Program of Shaanxi Province(Grant 2024GX-YBXM-512)2023 Qinchuangyuan Construction Two Chain Integration Special Project(23LLRH0043)Natural Science Basic Research Program of Shaanxi(2023-JC-QN-0681)Beijing Natural Science Foundation(IS23037)State Key Laboratory of Advanced Technology for Materials Synthesis and Processing(Wuhan University of Technology,2024-KF-12)the Xidian University Specially Funded Project for Interdisciplinary Exploration(TZJH2024052,TZJH2024050,TZJH2024065)Fundamental Research Funds for the Central Universities and the Innovation Fund of Xidian University.
文摘Although outstanding power conversion efficiency has been achieved in perovskite solar cells(PSCs),poor stability and lead(Pb)toxicity are still the key challenges limiting the commercial application of PSCs.Herein,we adopted both chemical encapsulation and physical encapsulation to address these problems.Via strong chemical interaction between dibutyl phthalate(DBP)and perovskite,the chemical encapsulation strategy results in higher perovskite film quality with reduced trap density,and the device efficiency enhances from 22.07%to 24.36%.Physical encapsulation polymer with high film robustness and self-healing properties could effectively isolate external risks and restore protection after physical damage.Furthermore,both chemical and physical encapsulation materials could trap Pb ions leaking from the perovskite materials by forming coordination interactions.We simulated realistic scenarios in which PSCs encapsulated by different methods suffered water immersion and mechanical damage,and quantitatively measured Pb leakage rates under different conditions.Higher device stability and greater Pb leakage reduction were achieved,confirming the excellent encapsulation effect of the synergy of chemical and physical encapsulation.This study provides an effective strategy to realize safe and environmentally friendly PSCs to promote their commercialization.
文摘Dendrimers are macromolecules characterized by high controlled size, shape and architecture, presence of inner cavities able to accommodate small molecules and many peripheral functional groups to bind target entities. They are of eminent interest for biomedical applications, including gene transfection, tissue engineering, imaging, and drug delivery. The well-known pharmacological activities of ursolic and oleanolic acids are limited by their small water solubility, non-specific cell distribution, low bioavailability, poor pharmacokinetics, and their direct administration could result in the release of thrombi. To overcome such problems, in this paper we described their physical incorporation inside amino acids-modified polyester-based dendrimers which made them highly water-soluble. IR, NMR, zeta potential, mean size of particles, buffer capacity and drug release profiles of prepared materials were reported. The achieved water-soluble complexes harmonize a polycationic character and a buffer capacity which presuppose efficient cell penetration and increased residence time with a biodegradable cell respectful scaffold, thus appearing as a promising team of not toxic prodrugs for safe administration of ursolic and oleanolic acids.
