Corticotomy is a clinical procedure to accelerate orthodontic tooth movement characterized by the regional acceleratory phenomenon(RAP).Despite its therapeutic effects,the surgical risk and unclear mechanism hamper th...Corticotomy is a clinical procedure to accelerate orthodontic tooth movement characterized by the regional acceleratory phenomenon(RAP).Despite its therapeutic effects,the surgical risk and unclear mechanism hamper the clinical application.Numerous evidences support macrophages as the key immune cells during bone remodeling.Our study discovered that the monocyte-derived macrophages primarily exhibited a pro-inflammatory phenotype that dominated bone remodeling in corticotomy by CX3CR1CreERT2;R26GFP lineage tracing system.Fluorescence staining,flow cytometry analysis,and western blot determined the significantly enhanced expression of binding immunoglobulin protein(BiP)and emphasized the activation of sensor activating transcription factor 6(ATF6)in macrophages.Then,we verified that macrophage specific ATF6 deletion(ATF6f/f;CX3CR1CreERT2 mice)decreased the proportion of pro-inflammatory macrophages and therefore blocked the acceleration effect of corticotomy.In contrast,macrophage ATF6 overexpression exaggerated the acceleration of orthodontic tooth movement.In vitro experiments also proved that higher proportion of pro-inflammatory macrophages was positively correlated with higher expression of ATF6.At the mechanism level,RNA-seq and CUT&Tag analysis demonstrated that ATF6 modulated the macrophage-orchestrated inflammation through interacting with Tnfαpromotor and augmenting its transcription.Additionally,molecular docking simulation and dual-luciferase reporter system indicated the possible binding sites outside of the traditional endoplasmic reticulum-stress response element(ERSE).Taken together,ATF6 may aggravate orthodontic bone remodeling by promoting Tnfαtranscription in macrophages,suggesting that ATF6 may represent a promising therapeutic target for non-invasive accelerated orthodontics.展开更多
The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the...The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the PGA immediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system.In this study,we propose a deep learning model,ConvMixer,to predict the PGA recorded by weak-motion velocity seismometers in Japan.We use 5-s threecomponent seismograms,from 2 s before until 3 s after the P-wave arrival time of the earthquake.Our dataset comprised more than 50,000 single-station waveforms recorded by 10 seismic stations in the K-NET,Kiki-NET,and Hi-Net networks between 2004 and 2023.The proposed ConvMixer is a patch-based model that extracts global features from input seismic data and predicts the PGA of an earthquake by combining depth and pointwise convolutions.The proposed ConvMixer network had a mean absolute error of 2.143 when applied to the test set and outperformed benchmark deep learning models.In addition,the proposed ConvMixer demonstrated the ability to predict the PGA at the corresponding station site based on 1-second waveforms obtained immediately after the arrival time of the P-wave.展开更多
Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)im...Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)improve interpretability by producing UK Biobank age-referenced centiles for PA volume and intensity;(b)inform public-health messaging by examining how adding recommended quantities of moderate and vigorous PA affect PA volume and intensity.Methods 92,480 UK Biobank participants aged 43-80 years with wrist-worn accelerometer data were included.Average acceleration and intensity gradient were derived as proxies for PA volume and intensity.We generated sex-specific centile curves using Generalized Additive Models for Location Scale and Shape(GAMLSS)and modeled the effect of adding moderate(walking)or vigorous(running)activity on the combined change in the volume and intensity centiles(change in PA profile).Results In men,volume was lower as age increased while intensity was lower after age 55;in women,both volume and intensity were lower as age increased.Adding 150 min of moderate PA weekly(5×30 min walking)increased the PA profile by 4 percentage points.Defining moderate PA as brisk walking approximately doubled the increase(9 percentage points)while 75 min of vigorous PA weekly(5×15 min running)trebled the increase(13 percentage points).Conclusion These UK Biobank reference centiles provide a benchmark for interpretation of accelerometer data.Application of our translational methods demonstrate that meeting PA guidelines through shorter duration vigorous activity is more beneficial to the PA profile(volume and intensity)than longer duration moderate activity.展开更多
In order to support the physical research on the EAST tokamak,a new positive ion source with designed beam energy of 120 keV was proposed to be developed.Accelerator structure is one of the key components of the ion s...In order to support the physical research on the EAST tokamak,a new positive ion source with designed beam energy of 120 keV was proposed to be developed.Accelerator structure is one of the key components of the ion source.Through the finite element analysis method,the electrostatic analyses of insulators and grid plates were carried out,the material and structure parameters of insulators were determined.The maximum electric field around each insulator is about 4 kV/mm,and the maximum electric field between grids is about 14 kV/mm,which can meet the 120 keV withstand voltage holding.The insulation system for the positive ion source accelerator with 120 keV is designed,and the connection and basic parameters of insulators and support flanges are analyzed and determined.展开更多
The harmonic balance method(HBM)has been widely applied to get the periodic solution of nonlinear systems,however,its convergence rate as well as computation efficiency is dramatically degraded when the system is high...The harmonic balance method(HBM)has been widely applied to get the periodic solution of nonlinear systems,however,its convergence rate as well as computation efficiency is dramatically degraded when the system is highly non-smooth,e.g.,discontinuous.In order to accelerate the convergence,an enriched HBM is developed in this paper where the non-smooth Bernoulli bases are additionally introduced to enrich the conventional Fourier bases.The basic idea behind is that the convergence rate of the HB solution,as a truncated Fourier series,can be improved if the smoothness of the solution becomes finer.Along this line,using non-smooth Bernoulli bases can compensate the highly non-smooth part of the solution and then,the smoothness of the residual part for Fourier approximation is improved so as to achieve accelerated convergence.Numerical examples are conducted on systems with non-smooth restoring and/or external forces.The results confirm that the proposed enriched HBM indeed increases the convergence rate and the increase becomes more significant if more non-smooth bases are used.展开更多
We report the world-leading performance of a 1.3 GHz cryomodule equipped with eight 9-cell superconducting radio-frequency cavities that underwent a medium-temperature furnace baking process.During continuous wave hor...We report the world-leading performance of a 1.3 GHz cryomodule equipped with eight 9-cell superconducting radio-frequency cavities that underwent a medium-temperature furnace baking process.During continuous wave horizontal testing,these cavities achieved unprecedented average intrinsic quality factors of 4.0×10^(10)at 20 MV/m and 3.2×10^(10)at 29 MV/m,with no instances of field emission.The cryomodule demonstrates near-complete preservation of ultra-high quality factors and ultra-high accelerating gradients from vertical to horizontal testing,marking a significant milestone in continuous-wave superconducting radio-frequency accelerator technology.This letter presents the cryomodule development experience,includ-ing cavity preparation,cryomodule assembly,degaussing,fast cooldown,and performance testing.展开更多
We study the average rate of change of energy of two accelerated entangled atoms coupled to electromagnetic fields in the presence of a reflecting boundary,which according to the Dalibard,Dupont-Roc and Cohen-Tannoudj...We study the average rate of change of energy of two accelerated entangled atoms coupled to electromagnetic fields in the presence of a reflecting boundary,which according to the Dalibard,Dupont-Roc and Cohen-Tannoudji formalism is only attributed to the contribution of the radiative reaction of atoms.When the boundary is present,this result can be expressed as the sum of the free-space result and the boundary-induced modifications,and it generally depends on the two-atom initial state,the orientations of atomic dipole moments,as well as the relative scales among atom-boundary distance,interatomic separation and the inverse of atomic acceleration.When the two atoms are vertically aligned and one atom is very close to the boundary,we find that the terms only related to the closer atom are zero for the symmetric state but double the free-space counterpart for the antisymmetric state,if the atom is polarizable parallel to the boundary.However,for the atom polarizable vertically to the boundary,these terms vanish for the antisymmetric state but are twice the free-space counterpart for the symmetric state.Moreover,the terms related to the farther atom exhibit obviously oscillatory behavior,and the terms related to both atoms are vanishing unless the dipole moments of two atoms both have their components vertical to the boundary.When the two atoms are aligned parallel to and very close to the boundary,the terms related to one atom are interatomicseparation-independent and only influenced by the atomic dipole moments.The terms related to both atoms are actually consistent with the counterpart in the vertical-alignment case.In addition,when the two atoms are polarizable along the direction parallel to the boundary,the average rate of change of energy of two parallel-aligned and symmetric entangled atoms vanishes as if the two atoms were a closed system.展开更多
Alcohol oxidation is a widely used green chemical reaction.The reaction process produces flammable and explosive hydrogen,so the design of the reactor must meet stringent safety requirements.Based on the limited exper...Alcohol oxidation is a widely used green chemical reaction.The reaction process produces flammable and explosive hydrogen,so the design of the reactor must meet stringent safety requirements.Based on the limited experimental data,utilizing the traditional numerical method of computational fluid dynamics(CFD)to simulate the gas-liquid two-phase flow reactor can mitigate the risk of danger under varying working conditions.However,the calculation process is highly time-consuming.Therefore,by integrating process simulation,computational fluid dynamics,and deep learning technologies,an intelligent hybrid chemical model based on machine learning was proposed to expedite CFD calculations,enhance the prediction of flow fields,conversion rates,and concentrations inside the reactor,and offer insights for designing and optimizing the reactor for the alcohol oxidation system.The results show that the hybrid model based on the long and short-term memory neural network achieves 99.8%accuracy in conversion rate prediction and 99.9%accuracy in product concentration prediction.Through validation,the hybrid model is accelerated by about 360 times compared with instrumental analysis in conversion rate prediction and about 45 times compared with CFD calculation in concentration distribution prediction.This hybrid model can quickly predict the conversion rate and product concentration distribution in the gas-liquid two-phase flow reactor and provide a model reference for fast prediction and accurate control in the actual chemical production process.展开更多
This study investigates the paradoxical detonation behavior of TKX-50,a nitrogen-rich energetic material,exhibiting higher detonation velocities but lower metal acceleration ability compared to HMX.Through experimenta...This study investigates the paradoxical detonation behavior of TKX-50,a nitrogen-rich energetic material,exhibiting higher detonation velocities but lower metal acceleration ability compared to HMX.Through experimental measurements and theoretical calculations,we propose a novel three-factor competition mechanism to explain this phenomenon.TKX-50-based PBX formulations achieved detonation velocities up to 9100 m/s,surpassing HMX-based counterparts.However,cylinder expansion tests revealed a 15%reduction in metal acceleration ability.Thermochemical measurements showed lower detonation heat for TKX-50(4900 J/g)versus HMX(5645 J/g).Our mechanism involves:(1)compositional effects prevailing at high pressures;(2)Energy release becoming essential as pressure drops;(3)Pressure-dependent product composition evolution functioning at low pressure.VLW code calculations unveiled a"crossover"in Hugoniot curves,lending support to this mechanism.This study furnishes a new framework for comprehending the performance of nitrogen-rich energetic materials,with significant implications for the design and optimization of future high-energy density materials.展开更多
Both acceleration and pseudo-acceleration response spectra play important roles in structural seismic design.However,only one of them is generally provided in most seismic codes.Therefore,many studies have attempted t...Both acceleration and pseudo-acceleration response spectra play important roles in structural seismic design.However,only one of them is generally provided in most seismic codes.Therefore,many studies have attempted to develop conversion models between the acceleration response spectrum(SA)and the pseudo-acceleration response spectrum(PSA).Our previous studies found that the relationship between SA and PSA is affected by magnitude,distance,and site class.Subsequently,we developed an SA/PSA model incorporating these effects.However,this model is suitable for cases with small and moderate magnitudes and its accuracy is not good enough for cases with large magnitudes.This paper aims to develop an efficient SA/PSA model by considering influences of magnitude,distance,and site class,which can be applied to cases not only with small or moderate magnitudes but also with large ones.For this purpose,regression analyses were conducted using 16,660 horizontal seismic records with a wider range of magnitude.The magnitude of these seismic records varies from 4 to 9 and the distances vary from 10 to 200 km.These ground motions were recorded at 338 stations covering four site classes.By comparing them with existing models,it was found that the proposed model shows better accuracy for cases with any magnitudes,distances,and site classes considered in this study.展开更多
Graph computing has become pervasive in many applications due to its capacity to represent complex relationships among different objects in the big data era.However,general-purpose architectures are computationally in...Graph computing has become pervasive in many applications due to its capacity to represent complex relationships among different objects in the big data era.However,general-purpose architectures are computationally inefficient for graph algorithms,and dedicated architectures can provide high efficiency,but lack flexibility.To address these challenges,this paper proposes ParaGraph,a reduced instruction set computing-five(RISC-V)-based software-hardware co-designed graph computing accelerator that can process graph algorithms in parallel,and also establishes a performance evaluation model to assess the efficiency of co-acceleration.ParaGraph handles parallel processing of typical graph algorithms on the hardware side,while performing overall functional control on the software side with custom designed instructions.ParaGraph is verified on the XCVU440 field-programmable gate array(FPGA)board with E203,a RISC-V processor.Compared with current mainstream graph computing accelerators,ParaGraph consumes 7.94%less block RAM(BRAM)resources than ThunderGP.Its power consumption is reduced by 86.90%,24.90%,and 76.38%compared with ThunderGP,HitGraph,and GraphS,respectively.The power efficiency of connected components(CC)and degree centrality(DC)algorithms is improved by an average of 6.50 times over ThunderGP,2.51 times over HitGraph,and 3.99 times over GraphS.The software-hardware co-design acceleration performance indicators H/W.Cap for CC and DC are 13.02 and 14.02,respectively.展开更多
Variable Cycle Engine(VCE)serves as the core system in achieving future advanced fighters with cross-generational performance and mission versatility.However,the resultant complex configuration and strong coupling of ...Variable Cycle Engine(VCE)serves as the core system in achieving future advanced fighters with cross-generational performance and mission versatility.However,the resultant complex configuration and strong coupling of control parameters present significant challenges in designing acceleration and deceleration control schedules.To thoroughly explore the performance potential of engine,a global integration design method for acceleration and deceleration control schedule based on inner and outer loop optimization is proposed.The outer loop optimization module employs Integrated Surrogate-Assisted Co-Differential Evolutionary(ISACDE)algorithm to optimize the variable geometry adjustment laws based on B-spline curve,and the inner loop optimization module adopts the fixed-state method to design the open-loop fuel–air ratio control schedules,which are aimed at minimizing the acceleration and deceleration time under multiple constraints.Simulation results demonstrate that the proposed global integration design method not only furthest shortens the acceleration and deceleration time,but also effectively safeguards the engine from overlimit.展开更多
Lost acceleration response reconstruction is crucial for assessing structural conditions in structural health monitoring(SHM).However,traditional methods struggle to address the reconstruction of acceleration response...Lost acceleration response reconstruction is crucial for assessing structural conditions in structural health monitoring(SHM).However,traditional methods struggle to address the reconstruction of acceleration responses with complex features,resulting in a lower reconstruction accuracy.This paper addresses this challenge by leveraging the advanced feature extraction and learning capabilities of fully convolutional networks(FCN)to achieve precise reconstruction of acceleration responses.In the designed network architecture,the incorporation of skip connections preserves low-level details of the network,greatly facilitating the flow of information and improving training efficiency and accuracy.Dropout techniques are employed to reduce computational load and enhance feature extraction.The proposed FCN model automatically extracts high-level features from the input data and establishes a nonlinearmapping relationship between the input and output responses.Finally,the accuracy of the FCN for structural response reconstructionwas evaluated using acceleration data from an experimental arch rib and comparedwith several traditional methods.Additionally,this approach was applied to reconstruct actual acceleration responses measured by an SHM system on a long-span bridge.Through parameter analysis,the feasibility and accuracy of aspects such as available response positions,the number of available channels,and multi-channel response reconstruction were explored.The results indicate that this method exhibits high-precision response reconstruction capability in both time and frequency domains.,with performance surpassing that of other networks,confirming its effectiveness in reconstructing responses under various sensor data loss scenarios.展开更多
The acceleration and mode transition performance are two significant performances of Adaptive Cycle Engine(ACE).However,separating the processes of acceleration and mode transition will slow down the response speed of...The acceleration and mode transition performance are two significant performances of Adaptive Cycle Engine(ACE).However,separating the processes of acceleration and mode transition will slow down the response speed of thrust.Therefore,this paper proposes a multi-mode acceleration optimization control method that simultaneously performs ACE acceleration and mode transition.Firstly,an ACE component model with inlet flow characteristics was established,and the performance before and after mode transition were analyzed.Secondly,the principle of ACE acceleration optimization was analyzed,and the Front Variable Area Bypass Injector(FVABI)and Mode Selection Valve(MSV)were adopted in the acceleration process.Finally,based on the Sequential Quadratic Programming(SQP)algorithm,considering the degradation effects of engine components,we optimize the acceleration control plan for fuel and variable geometry mechanisms.The simulation results show that at the subsonic cruise point,the ACE multi-mode acceleration optimization control method can shorten the acceleration time from idle to middle state by 30.33%,and accelerate the thrust response speed by 33.72%.When the compressor flow rate of ACE deteriorates by 2% and the high-pressure turbine efficiency deteriorates by 4%,the adaptive acceleration control plan increases the high-pressure speed by 2.13% and thrust by about 6.82%;within the flight envelope,the acceleration time is reduced by more than 25%,and the thrust response speed is increased by more than 20%.展开更多
Based on the mass-energy equation of special relativity and the assumption of the helical motion of light speed in cosmic space,we have theoretically demonstrated the true implications of Planck’s physical quantities...Based on the mass-energy equation of special relativity and the assumption of the helical motion of light speed in cosmic space,we have theoretically demonstrated the true implications of Planck’s physical quantities:Planck length and time represent the step size and period of the helical motion of light speed in the earliest cosmic space following the Big Bang;Planck energy constitutes the minimum energy unit associated with this spatial helical motion;Planck mass is the mass derived from this minimum energy unit.In accordance with the expression of Planck time,we have derived the relationship formula between gravitational acceleration and the speed of light,thereby uncovering an inevitable intrinsic connection between the gravitational field and the electromagnetic field,and indicating that the four fundamental forces in the universe can be unified.Finally,through our spatial helical motion model,we computed the specific values of the four fundamental forces at the moment of strong nuclear force separation.The results reveal that they are in complete agreement with the theoretical calculation values or experimental values in modern physics and quantum mechanics,thereby providing an interesting hint for the unified field theories.展开更多
To address the issues of low solving efficiency and poor decoupling accuracy in existing six-axis acceleration decoupling algorithms,a new decoupling algorithm is proposed along with a corresponding auto-compensation ...To address the issues of low solving efficiency and poor decoupling accuracy in existing six-axis acceleration decoupling algorithms,a new decoupling algorithm is proposed along with a corresponding auto-compensation algorithm.Firstly,based on Kane’s method,the dynamics model of the six-axis acceleration sensing mechanism is formed to determine the relationship between accelerations and branch forces.Then,with the trapezoidal rule,a solution algorithm for the dynamics model is developed.The virtual prototype tests show that the computation of this algorithm is five times more efficient than that of the ADAMS core algorithm.Besides,this solution algorithm is applied to the“12-6”configuration and“9-3”configuration.The results show that the efficiency of the former is nearly 3.3 times that of the latter.Finally,based on vibration theory,an auto-compensation algorithm for the solution algorithm is established.Virtual prototype tests indicate that with 40%noise interference,the auto-compensation algorithm achieves misjudgement rate and omission rate of only 4.0%and 4.5%,respectively,and the errors in the solving process converge.展开更多
Aqueous zincion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion migration.To address this,a strategy has been d...Aqueous zincion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion migration.To address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn^(2+)diffusion kinetics.By employing electrodeposition to coat MoS_(2)on the surface of BaV_(6)O_(16)·3H_(2)O nanowires,the directional builtin electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn^(2+)diffusion into the active material.The optimized Zn^(2+)diffusion coefficient in CC@BaV-V_(6)O_(16)·3H_(2)@MoS_(2)(7.5×10^(8)cm^(2)s^(-1)) surpasses that of most reported V-based cathodes.Simultaneously,MoS_(2)serving as a cathodic armor extends the cycling life of the Zn-CC@BaV_(6)O_(16)·3H_(2)@MoS_(2)full batteries to over 10000 cycles.This work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.展开更多
This research examines the dynamics of a cosh-Gaussian laser pulse travelling through a vacuum and its impact on electron acceleration. We examine the impact of several critical factors, such as laser electric field a...This research examines the dynamics of a cosh-Gaussian laser pulse travelling through a vacuum and its impact on electron acceleration. We examine the impact of several critical factors, such as laser electric field amplitude, decentered parameter, beam waist, and laser chirp parameter, on the energy gain of electrons using coupled momentum equations. Our results indicate that the energy acquisition of electrons escalates with the amplitude of the laser electric field, decentered parameter, and chirp parameter. An appropriate beam waist is essential for attaining energyefficient electron acceleration in a vacuum. Through the optimization of these parameters, we get a maximum electron energy gain of 2.80 Ge V. This study highlights the significance of customized laser pulse attributes in improving electron acceleration and aids in the progression of high-energy particle physics.展开更多
AIM:To assess the visual outcomes and corneal biomechanical properties of myopia patients between laser in situ keratomileusis(LASIK)and LASIK combined with accelerated corneal crosslinking(LASIK Xtra).METHODS:This pr...AIM:To assess the visual outcomes and corneal biomechanical properties of myopia patients between laser in situ keratomileusis(LASIK)and LASIK combined with accelerated corneal crosslinking(LASIK Xtra).METHODS:This prospective study analyzed 52 consecutive myopia patients treated with LASIK Xtra and 45 consecutive myopia patients treated with LASIK.Only the right eyes in the two groups were analyzed.The uncorrected distance visual acuity(UDVA),keratometry values,postoperative central corneal thickness(CCT),corneal demarcation line depth,the corneal compensated intraocular pressure(IOPcc),Goldmann-correlated IOP(IOPg),corneal resistance factor(CRF)and corneal hysteresis(CH)from Ocular Response Analyzer(ORA)were analyzed.Further,the correlation between the demarcation line depth and ORA-related biomechanical parameters were analyzed.RESULTS:No significant differences in UDVA,postoperative CCT,or mean K values were found between the 2 groups at 1 to 12mo postoperative follow-up(all P>0.05).The changes of CRF was significantly lower in the LASIK Xtra group compared to the LASIK group(all P<0.05)at all the postoperative visits.The changes of CH were significantly higher in the LASIK Xtra group(all P<0.05).No significant differences were discovered regarding the changes of IOPcc and IOPg posperatively(all P>0.05).Out of 52 cases in the LASIK Xtra group,the demarcation line was present in 40 eyes(77%).The average depth of the demarcation was 220.73±42.70μm(136 to 288μm).No significant correlation was observed between the depth of the demarcation line and any of the ORA-related biomechanical parameters such as IOPcc,IOPg,CRF and CH at 12mo(all P>0.05).CONCLUSION:Both procedures demonstrate comparable outcomes in terms of visual acuity,refraction and ablation predictability.This study confirms that corneal biomechanical properties of the included patients weakened after both procedures,but the cornea after LASIK Xtra are stiffer than conventional LASIK.展开更多
The article contains an error regarding the electron spectra displayed in Figs.4 and 5 and the data extracted from these spectra.The measurements were made with the SESAME magnetic spectrometer,the working principle o...The article contains an error regarding the electron spectra displayed in Figs.4 and 5 and the data extracted from these spectra.The measurements were made with the SESAME magnetic spectrometer,the working principle of which is recalled in Fig.1.Specifically,a magnetic dipole is used to separate charged particles(electrons in the case of this experiment)depending on their energy,charge and mass.The deflected particles then hit an imaging plate(IP)and deposit energy in its sensitive layer.The kinetic energy of the particles can be evaluated from their impact position on the IP and their number can be inferred from the local energy deposition.展开更多
基金supported by the National Natural Science Foundation of China(82071143,82371000,82270361)Key Research and Development Program of Jiangsu Province(BE2022795)+2 种基金the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX22_1801)the Jiangsu Province Capability Improvement Project through the Science,Technology and Education-Jiangsu Provincial Research Hospital Cultivation Unit(YJXYYJSDW4)Jiangsu Provincial Medical Innovation Center(CXZX202227).
文摘Corticotomy is a clinical procedure to accelerate orthodontic tooth movement characterized by the regional acceleratory phenomenon(RAP).Despite its therapeutic effects,the surgical risk and unclear mechanism hamper the clinical application.Numerous evidences support macrophages as the key immune cells during bone remodeling.Our study discovered that the monocyte-derived macrophages primarily exhibited a pro-inflammatory phenotype that dominated bone remodeling in corticotomy by CX3CR1CreERT2;R26GFP lineage tracing system.Fluorescence staining,flow cytometry analysis,and western blot determined the significantly enhanced expression of binding immunoglobulin protein(BiP)and emphasized the activation of sensor activating transcription factor 6(ATF6)in macrophages.Then,we verified that macrophage specific ATF6 deletion(ATF6f/f;CX3CR1CreERT2 mice)decreased the proportion of pro-inflammatory macrophages and therefore blocked the acceleration effect of corticotomy.In contrast,macrophage ATF6 overexpression exaggerated the acceleration of orthodontic tooth movement.In vitro experiments also proved that higher proportion of pro-inflammatory macrophages was positively correlated with higher expression of ATF6.At the mechanism level,RNA-seq and CUT&Tag analysis demonstrated that ATF6 modulated the macrophage-orchestrated inflammation through interacting with Tnfαpromotor and augmenting its transcription.Additionally,molecular docking simulation and dual-luciferase reporter system indicated the possible binding sites outside of the traditional endoplasmic reticulum-stress response element(ERSE).Taken together,ATF6 may aggravate orthodontic bone remodeling by promoting Tnfαtranscription in macrophages,suggesting that ATF6 may represent a promising therapeutic target for non-invasive accelerated orthodontics.
基金the National Research Institute of Astronomy and Geophysics (NRIAG) for supporting this work
文摘The level of ground shaking,as determined by the peak ground acceleration(PGA),can be used to analyze seismic hazard at a certain location and is crucial for constructing earthquake-resistant structures.Predicting the PGA immediately after an earthquake occurs allows for the issuing of a warning by an earthquake early warning system.In this study,we propose a deep learning model,ConvMixer,to predict the PGA recorded by weak-motion velocity seismometers in Japan.We use 5-s threecomponent seismograms,from 2 s before until 3 s after the P-wave arrival time of the earthquake.Our dataset comprised more than 50,000 single-station waveforms recorded by 10 seismic stations in the K-NET,Kiki-NET,and Hi-Net networks between 2004 and 2023.The proposed ConvMixer is a patch-based model that extracts global features from input seismic data and predicts the PGA of an earthquake by combining depth and pointwise convolutions.The proposed ConvMixer network had a mean absolute error of 2.143 when applied to the test set and outperformed benchmark deep learning models.In addition,the proposed ConvMixer demonstrated the ability to predict the PGA at the corresponding station site based on 1-second waveforms obtained immediately after the arrival time of the P-wave.
基金supported by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre and NIHR Applied Research Collaboration East Midlands (ARC EM, (IS-BRC-1215-20010))funded by the National Institute for Health and Care Research Bristol Biomedical Research Centre (IS-BRC-1215-20011)supported by a UKRI research grant (EP/X042464/1)。
文摘Background Higher accelerometer-assessed volume and intensity of physical activity(PA)have been associated with a longer life expectancy but can be difficult to translate into recommended doses of PA.We aimed to:(a)improve interpretability by producing UK Biobank age-referenced centiles for PA volume and intensity;(b)inform public-health messaging by examining how adding recommended quantities of moderate and vigorous PA affect PA volume and intensity.Methods 92,480 UK Biobank participants aged 43-80 years with wrist-worn accelerometer data were included.Average acceleration and intensity gradient were derived as proxies for PA volume and intensity.We generated sex-specific centile curves using Generalized Additive Models for Location Scale and Shape(GAMLSS)and modeled the effect of adding moderate(walking)or vigorous(running)activity on the combined change in the volume and intensity centiles(change in PA profile).Results In men,volume was lower as age increased while intensity was lower after age 55;in women,both volume and intensity were lower as age increased.Adding 150 min of moderate PA weekly(5×30 min walking)increased the PA profile by 4 percentage points.Defining moderate PA as brisk walking approximately doubled the increase(9 percentage points)while 75 min of vigorous PA weekly(5×15 min running)trebled the increase(13 percentage points).Conclusion These UK Biobank reference centiles provide a benchmark for interpretation of accelerometer data.Application of our translational methods demonstrate that meeting PA guidelines through shorter duration vigorous activity is more beneficial to the PA profile(volume and intensity)than longer duration moderate activity.
基金supported by National Natural Science Foundation of China(No.11975261)。
文摘In order to support the physical research on the EAST tokamak,a new positive ion source with designed beam energy of 120 keV was proposed to be developed.Accelerator structure is one of the key components of the ion source.Through the finite element analysis method,the electrostatic analyses of insulators and grid plates were carried out,the material and structure parameters of insulators were determined.The maximum electric field around each insulator is about 4 kV/mm,and the maximum electric field between grids is about 14 kV/mm,which can meet the 120 keV withstand voltage holding.The insulation system for the positive ion source accelerator with 120 keV is designed,and the connection and basic parameters of insulators and support flanges are analyzed and determined.
基金supported by the National Natural Science Foundation of China (Grant No. 12372028)the National Key Research and Development Program of China (Grant No. 2020YFC2201101)the Guangdong Basic and Applied Basic Research Foundation (Grant No.2022A1515011809)。
文摘The harmonic balance method(HBM)has been widely applied to get the periodic solution of nonlinear systems,however,its convergence rate as well as computation efficiency is dramatically degraded when the system is highly non-smooth,e.g.,discontinuous.In order to accelerate the convergence,an enriched HBM is developed in this paper where the non-smooth Bernoulli bases are additionally introduced to enrich the conventional Fourier bases.The basic idea behind is that the convergence rate of the HB solution,as a truncated Fourier series,can be improved if the smoothness of the solution becomes finer.Along this line,using non-smooth Bernoulli bases can compensate the highly non-smooth part of the solution and then,the smoothness of the residual part for Fourier approximation is improved so as to achieve accelerated convergence.Numerical examples are conducted on systems with non-smooth restoring and/or external forces.The results confirm that the proposed enriched HBM indeed increases the convergence rate and the increase becomes more significant if more non-smooth bases are used.
基金supported by Zhangjiang Laboratory,the SHINE R&D project(No.2017SHZDZX02)the SHINE projectthe National Natural Science Foundation of China(No.12125508).
文摘We report the world-leading performance of a 1.3 GHz cryomodule equipped with eight 9-cell superconducting radio-frequency cavities that underwent a medium-temperature furnace baking process.During continuous wave horizontal testing,these cavities achieved unprecedented average intrinsic quality factors of 4.0×10^(10)at 20 MV/m and 3.2×10^(10)at 29 MV/m,with no instances of field emission.The cryomodule demonstrates near-complete preservation of ultra-high quality factors and ultra-high accelerating gradients from vertical to horizontal testing,marking a significant milestone in continuous-wave superconducting radio-frequency accelerator technology.This letter presents the cryomodule development experience,includ-ing cavity preparation,cryomodule assembly,degaussing,fast cooldown,and performance testing.
基金supported in part by the NSFC under Grant Nos.12047551 and 12105061the Graduate Innovation Project of Shanxi Normal University under Grant No.2023XSY041。
文摘We study the average rate of change of energy of two accelerated entangled atoms coupled to electromagnetic fields in the presence of a reflecting boundary,which according to the Dalibard,Dupont-Roc and Cohen-Tannoudji formalism is only attributed to the contribution of the radiative reaction of atoms.When the boundary is present,this result can be expressed as the sum of the free-space result and the boundary-induced modifications,and it generally depends on the two-atom initial state,the orientations of atomic dipole moments,as well as the relative scales among atom-boundary distance,interatomic separation and the inverse of atomic acceleration.When the two atoms are vertically aligned and one atom is very close to the boundary,we find that the terms only related to the closer atom are zero for the symmetric state but double the free-space counterpart for the antisymmetric state,if the atom is polarizable parallel to the boundary.However,for the atom polarizable vertically to the boundary,these terms vanish for the antisymmetric state but are twice the free-space counterpart for the symmetric state.Moreover,the terms related to the farther atom exhibit obviously oscillatory behavior,and the terms related to both atoms are vanishing unless the dipole moments of two atoms both have their components vertical to the boundary.When the two atoms are aligned parallel to and very close to the boundary,the terms related to one atom are interatomicseparation-independent and only influenced by the atomic dipole moments.The terms related to both atoms are actually consistent with the counterpart in the vertical-alignment case.In addition,when the two atoms are polarizable along the direction parallel to the boundary,the average rate of change of energy of two parallel-aligned and symmetric entangled atoms vanishes as if the two atoms were a closed system.
基金the support from the National Natural Science Foundation of China(22478429)the Special Project Fund of Taishan-Scholars(tsqn202408101)+3 种基金the Natural Science Foundation of Shandong Province(ZR2023YQ009)CNPC Innovation Found(2024DQ02-0504)Fundamental Research Funds for the Central Universities,Ocean University of China(202364004)the State Key Laboratory of Heavy Oil Processing(SKLHOP202403003)。
文摘Alcohol oxidation is a widely used green chemical reaction.The reaction process produces flammable and explosive hydrogen,so the design of the reactor must meet stringent safety requirements.Based on the limited experimental data,utilizing the traditional numerical method of computational fluid dynamics(CFD)to simulate the gas-liquid two-phase flow reactor can mitigate the risk of danger under varying working conditions.However,the calculation process is highly time-consuming.Therefore,by integrating process simulation,computational fluid dynamics,and deep learning technologies,an intelligent hybrid chemical model based on machine learning was proposed to expedite CFD calculations,enhance the prediction of flow fields,conversion rates,and concentrations inside the reactor,and offer insights for designing and optimizing the reactor for the alcohol oxidation system.The results show that the hybrid model based on the long and short-term memory neural network achieves 99.8%accuracy in conversion rate prediction and 99.9%accuracy in product concentration prediction.Through validation,the hybrid model is accelerated by about 360 times compared with instrumental analysis in conversion rate prediction and about 45 times compared with CFD calculation in concentration distribution prediction.This hybrid model can quickly predict the conversion rate and product concentration distribution in the gas-liquid two-phase flow reactor and provide a model reference for fast prediction and accurate control in the actual chemical production process.
基金support provided by the National Natural Science Foundation of China(Grant No.12102405)the Presidential Foundation of CAEP(Grant No.YZJJZQ2023008).
文摘This study investigates the paradoxical detonation behavior of TKX-50,a nitrogen-rich energetic material,exhibiting higher detonation velocities but lower metal acceleration ability compared to HMX.Through experimental measurements and theoretical calculations,we propose a novel three-factor competition mechanism to explain this phenomenon.TKX-50-based PBX formulations achieved detonation velocities up to 9100 m/s,surpassing HMX-based counterparts.However,cylinder expansion tests revealed a 15%reduction in metal acceleration ability.Thermochemical measurements showed lower detonation heat for TKX-50(4900 J/g)versus HMX(5645 J/g).Our mechanism involves:(1)compositional effects prevailing at high pressures;(2)Energy release becoming essential as pressure drops;(3)Pressure-dependent product composition evolution functioning at low pressure.VLW code calculations unveiled a"crossover"in Hugoniot curves,lending support to this mechanism.This study furnishes a new framework for comprehending the performance of nitrogen-rich energetic materials,with significant implications for the design and optimization of future high-energy density materials.
基金National Natural Science Foundation of China under Grant No.52278135。
文摘Both acceleration and pseudo-acceleration response spectra play important roles in structural seismic design.However,only one of them is generally provided in most seismic codes.Therefore,many studies have attempted to develop conversion models between the acceleration response spectrum(SA)and the pseudo-acceleration response spectrum(PSA).Our previous studies found that the relationship between SA and PSA is affected by magnitude,distance,and site class.Subsequently,we developed an SA/PSA model incorporating these effects.However,this model is suitable for cases with small and moderate magnitudes and its accuracy is not good enough for cases with large magnitudes.This paper aims to develop an efficient SA/PSA model by considering influences of magnitude,distance,and site class,which can be applied to cases not only with small or moderate magnitudes but also with large ones.For this purpose,regression analyses were conducted using 16,660 horizontal seismic records with a wider range of magnitude.The magnitude of these seismic records varies from 4 to 9 and the distances vary from 10 to 200 km.These ground motions were recorded at 338 stations covering four site classes.By comparing them with existing models,it was found that the proposed model shows better accuracy for cases with any magnitudes,distances,and site classes considered in this study.
基金Supported by the National Key R&D Program of China(No.2022ZD0119001)the National Natural Science Foundation of China(No.61834005)+1 种基金the Shaanxi Province Key R&D Plan(No.2022GY-027,2021GY-029)the Key Scientific Research Project of Shaanxi Department of Education(No.22JY060).
文摘Graph computing has become pervasive in many applications due to its capacity to represent complex relationships among different objects in the big data era.However,general-purpose architectures are computationally inefficient for graph algorithms,and dedicated architectures can provide high efficiency,but lack flexibility.To address these challenges,this paper proposes ParaGraph,a reduced instruction set computing-five(RISC-V)-based software-hardware co-designed graph computing accelerator that can process graph algorithms in parallel,and also establishes a performance evaluation model to assess the efficiency of co-acceleration.ParaGraph handles parallel processing of typical graph algorithms on the hardware side,while performing overall functional control on the software side with custom designed instructions.ParaGraph is verified on the XCVU440 field-programmable gate array(FPGA)board with E203,a RISC-V processor.Compared with current mainstream graph computing accelerators,ParaGraph consumes 7.94%less block RAM(BRAM)resources than ThunderGP.Its power consumption is reduced by 86.90%,24.90%,and 76.38%compared with ThunderGP,HitGraph,and GraphS,respectively.The power efficiency of connected components(CC)and degree centrality(DC)algorithms is improved by an average of 6.50 times over ThunderGP,2.51 times over HitGraph,and 3.99 times over GraphS.The software-hardware co-design acceleration performance indicators H/W.Cap for CC and DC are 13.02 and 14.02,respectively.
基金supported by the Basic Research on Dynamic Real-time Modeling and Onboard Adaptive Modeling of Aero Engine,China(No.QZPY202308)。
文摘Variable Cycle Engine(VCE)serves as the core system in achieving future advanced fighters with cross-generational performance and mission versatility.However,the resultant complex configuration and strong coupling of control parameters present significant challenges in designing acceleration and deceleration control schedules.To thoroughly explore the performance potential of engine,a global integration design method for acceleration and deceleration control schedule based on inner and outer loop optimization is proposed.The outer loop optimization module employs Integrated Surrogate-Assisted Co-Differential Evolutionary(ISACDE)algorithm to optimize the variable geometry adjustment laws based on B-spline curve,and the inner loop optimization module adopts the fixed-state method to design the open-loop fuel–air ratio control schedules,which are aimed at minimizing the acceleration and deceleration time under multiple constraints.Simulation results demonstrate that the proposed global integration design method not only furthest shortens the acceleration and deceleration time,but also effectively safeguards the engine from overlimit.
基金National Natural Science Foundation of China(Grant Nos.52408314,52278292)Chongqing Outstanding Youth Science Foundation(Grant No.CSTB2023NSCQ-JQX0029)+1 种基金Science and Technology Project of Sichuan Provincial Transportation Department(Grant No.2023-ZL-03)Science and Technology Project of Guizhou Provincial Transportation Department(Grant No.2024-122-018).
文摘Lost acceleration response reconstruction is crucial for assessing structural conditions in structural health monitoring(SHM).However,traditional methods struggle to address the reconstruction of acceleration responses with complex features,resulting in a lower reconstruction accuracy.This paper addresses this challenge by leveraging the advanced feature extraction and learning capabilities of fully convolutional networks(FCN)to achieve precise reconstruction of acceleration responses.In the designed network architecture,the incorporation of skip connections preserves low-level details of the network,greatly facilitating the flow of information and improving training efficiency and accuracy.Dropout techniques are employed to reduce computational load and enhance feature extraction.The proposed FCN model automatically extracts high-level features from the input data and establishes a nonlinearmapping relationship between the input and output responses.Finally,the accuracy of the FCN for structural response reconstructionwas evaluated using acceleration data from an experimental arch rib and comparedwith several traditional methods.Additionally,this approach was applied to reconstruct actual acceleration responses measured by an SHM system on a long-span bridge.Through parameter analysis,the feasibility and accuracy of aspects such as available response positions,the number of available channels,and multi-channel response reconstruction were explored.The results indicate that this method exhibits high-precision response reconstruction capability in both time and frequency domains.,with performance surpassing that of other networks,confirming its effectiveness in reconstructing responses under various sensor data loss scenarios.
基金supported in part by the National Natural Science Foundation of China(No.52372389)the Jiangsu Province Excellent Postdoctoral Program of China(No.2023ZB494)+1 种基金the Basic Research Program of Jiangsu Province,China(No.BK20241412)the National Science Foundation for Post-doctoral Scientists of China(No.2024M754131)。
文摘The acceleration and mode transition performance are two significant performances of Adaptive Cycle Engine(ACE).However,separating the processes of acceleration and mode transition will slow down the response speed of thrust.Therefore,this paper proposes a multi-mode acceleration optimization control method that simultaneously performs ACE acceleration and mode transition.Firstly,an ACE component model with inlet flow characteristics was established,and the performance before and after mode transition were analyzed.Secondly,the principle of ACE acceleration optimization was analyzed,and the Front Variable Area Bypass Injector(FVABI)and Mode Selection Valve(MSV)were adopted in the acceleration process.Finally,based on the Sequential Quadratic Programming(SQP)algorithm,considering the degradation effects of engine components,we optimize the acceleration control plan for fuel and variable geometry mechanisms.The simulation results show that at the subsonic cruise point,the ACE multi-mode acceleration optimization control method can shorten the acceleration time from idle to middle state by 30.33%,and accelerate the thrust response speed by 33.72%.When the compressor flow rate of ACE deteriorates by 2% and the high-pressure turbine efficiency deteriorates by 4%,the adaptive acceleration control plan increases the high-pressure speed by 2.13% and thrust by about 6.82%;within the flight envelope,the acceleration time is reduced by more than 25%,and the thrust response speed is increased by more than 20%.
文摘Based on the mass-energy equation of special relativity and the assumption of the helical motion of light speed in cosmic space,we have theoretically demonstrated the true implications of Planck’s physical quantities:Planck length and time represent the step size and period of the helical motion of light speed in the earliest cosmic space following the Big Bang;Planck energy constitutes the minimum energy unit associated with this spatial helical motion;Planck mass is the mass derived from this minimum energy unit.In accordance with the expression of Planck time,we have derived the relationship formula between gravitational acceleration and the speed of light,thereby uncovering an inevitable intrinsic connection between the gravitational field and the electromagnetic field,and indicating that the four fundamental forces in the universe can be unified.Finally,through our spatial helical motion model,we computed the specific values of the four fundamental forces at the moment of strong nuclear force separation.The results reveal that they are in complete agreement with the theoretical calculation values or experimental values in modern physics and quantum mechanics,thereby providing an interesting hint for the unified field theories.
基金supported by the Opening Project of State Key Laboratory of Mechanical Transmission for Advanced Equipment(No.SKLMT-MSKFKT202330)the National Natural Science Foundation of China(NSFC)(No.52575022)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX24_1295)。
文摘To address the issues of low solving efficiency and poor decoupling accuracy in existing six-axis acceleration decoupling algorithms,a new decoupling algorithm is proposed along with a corresponding auto-compensation algorithm.Firstly,based on Kane’s method,the dynamics model of the six-axis acceleration sensing mechanism is formed to determine the relationship between accelerations and branch forces.Then,with the trapezoidal rule,a solution algorithm for the dynamics model is developed.The virtual prototype tests show that the computation of this algorithm is five times more efficient than that of the ADAMS core algorithm.Besides,this solution algorithm is applied to the“12-6”configuration and“9-3”configuration.The results show that the efficiency of the former is nearly 3.3 times that of the latter.Finally,based on vibration theory,an auto-compensation algorithm for the solution algorithm is established.Virtual prototype tests indicate that with 40%noise interference,the auto-compensation algorithm achieves misjudgement rate and omission rate of only 4.0%and 4.5%,respectively,and the errors in the solving process converge.
基金National Natural Science Foundation of China (61761047 and 41876055)Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province。
文摘Aqueous zincion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is limited by slow ion migration.To address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn^(2+)diffusion kinetics.By employing electrodeposition to coat MoS_(2)on the surface of BaV_(6)O_(16)·3H_(2)O nanowires,the directional builtin electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn^(2+)diffusion into the active material.The optimized Zn^(2+)diffusion coefficient in CC@BaV-V_(6)O_(16)·3H_(2)@MoS_(2)(7.5×10^(8)cm^(2)s^(-1)) surpasses that of most reported V-based cathodes.Simultaneously,MoS_(2)serving as a cathodic armor extends the cycling life of the Zn-CC@BaV_(6)O_(16)·3H_(2)@MoS_(2)full batteries to over 10000 cycles.This work provides valuable insights into optimizing ion diffusion kinetics for high-performance energy storage devices.
文摘This research examines the dynamics of a cosh-Gaussian laser pulse travelling through a vacuum and its impact on electron acceleration. We examine the impact of several critical factors, such as laser electric field amplitude, decentered parameter, beam waist, and laser chirp parameter, on the energy gain of electrons using coupled momentum equations. Our results indicate that the energy acquisition of electrons escalates with the amplitude of the laser electric field, decentered parameter, and chirp parameter. An appropriate beam waist is essential for attaining energyefficient electron acceleration in a vacuum. Through the optimization of these parameters, we get a maximum electron energy gain of 2.80 Ge V. This study highlights the significance of customized laser pulse attributes in improving electron acceleration and aids in the progression of high-energy particle physics.
基金Supported by Wu Jieping Medical Foundation(No.320.6750.2021-04-15).
文摘AIM:To assess the visual outcomes and corneal biomechanical properties of myopia patients between laser in situ keratomileusis(LASIK)and LASIK combined with accelerated corneal crosslinking(LASIK Xtra).METHODS:This prospective study analyzed 52 consecutive myopia patients treated with LASIK Xtra and 45 consecutive myopia patients treated with LASIK.Only the right eyes in the two groups were analyzed.The uncorrected distance visual acuity(UDVA),keratometry values,postoperative central corneal thickness(CCT),corneal demarcation line depth,the corneal compensated intraocular pressure(IOPcc),Goldmann-correlated IOP(IOPg),corneal resistance factor(CRF)and corneal hysteresis(CH)from Ocular Response Analyzer(ORA)were analyzed.Further,the correlation between the demarcation line depth and ORA-related biomechanical parameters were analyzed.RESULTS:No significant differences in UDVA,postoperative CCT,or mean K values were found between the 2 groups at 1 to 12mo postoperative follow-up(all P>0.05).The changes of CRF was significantly lower in the LASIK Xtra group compared to the LASIK group(all P<0.05)at all the postoperative visits.The changes of CH were significantly higher in the LASIK Xtra group(all P<0.05).No significant differences were discovered regarding the changes of IOPcc and IOPg posperatively(all P>0.05).Out of 52 cases in the LASIK Xtra group,the demarcation line was present in 40 eyes(77%).The average depth of the demarcation was 220.73±42.70μm(136 to 288μm).No significant correlation was observed between the depth of the demarcation line and any of the ORA-related biomechanical parameters such as IOPcc,IOPg,CRF and CH at 12mo(all P>0.05).CONCLUSION:Both procedures demonstrate comparable outcomes in terms of visual acuity,refraction and ablation predictability.This study confirms that corneal biomechanical properties of the included patients weakened after both procedures,but the cornea after LASIK Xtra are stiffer than conventional LASIK.
文摘The article contains an error regarding the electron spectra displayed in Figs.4 and 5 and the data extracted from these spectra.The measurements were made with the SESAME magnetic spectrometer,the working principle of which is recalled in Fig.1.Specifically,a magnetic dipole is used to separate charged particles(electrons in the case of this experiment)depending on their energy,charge and mass.The deflected particles then hit an imaging plate(IP)and deposit energy in its sensitive layer.The kinetic energy of the particles can be evaluated from their impact position on the IP and their number can be inferred from the local energy deposition.
