In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turn...In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turning vehicles at the beginning of a green phase at two similar intersections(one with a permitted phase and the other with a protected phase).The comparative analysis shows no significant difference in the speed distribution using either a permitted phase or a protected phase,but it reveals that a permitted phase can lead to a larger acceleration when the left-turn vehicles pass through the conflict points.Those indicate the existence of non-yielding maneuvers of left-turn vehicles at signalized intersections with a permitted phase.Optimal designed left-lane line extensions contain two types of segments,circular curves and transition curves,and they are only related to four geometry parameters of an intersection.The proposed method is easy to use and it can offer reference for intersection channelization and traffic organization.展开更多
Elemental impurities(EIs)in drug products are a specific class of inorganic contaminants that may originate from various sources.These residual impurities provide no therapeutic benefit to patients and,in some cases,m...Elemental impurities(EIs)in drug products are a specific class of inorganic contaminants that may originate from various sources.These residual impurities provide no therapeutic benefit to patients and,in some cases,may even catalyze the degradation of drug substances.Therefore,their levels in drug products must be controlled within acceptable limits.The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use(ICH)approved the harmonised Guideline for Elemental Impurities(ICH Q3D)on November 12,2014.On January 10,2020,the National Medical Products Administration(NMPA)announced the adoption of the ICH Q3D principles in China.Inductively coupled plasma mass spectrometry(ICP-MS)offers distinct advantages in detecting trace levels of EIs in drug products.Various validation criteria for the analytical procedure of ICP-MS are specified in the pharmacopoeias.This study compared differences in the validation criteria for ICP-MS,highlighting that the criteria adopted in the United States Pharmacopeia(USP)and European Pharmacopoeia(EP)were particularly specific and detailed,thereby facilitating analytical method development for drug quality control.The aim was to provide a useful reference for analysts conducting EI determination using ICP-MS.展开更多
Saud Khan,a Pakistani physician,collected his work and residence permits at the Yangpu Government Service Centre in Danzhou City,Hainan Province,on 18 December 2025.Khan had arrived in Hainan three months earlier to p...Saud Khan,a Pakistani physician,collected his work and residence permits at the Yangpu Government Service Centre in Danzhou City,Hainan Province,on 18 December 2025.Khan had arrived in Hainan three months earlier to participate in a medical training programme at Hainan Western Central Hospital.By the time the programme concluded,he had made up his mind to stay and broaden his professional experience and long-term career prospects in Hainan.展开更多
Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general contr...Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general control zones—are established based on the ecological red line,the lower-limit line for environmental quality,and the resource use line.Human activities are regulated through a permit system.Integrated and multifactorial protection of soil,plant,hydrological,and atmospheric elements is promoted at the regional level.A follow-up assessment contributes to the improvement of policy implementation and effectiveness.This study demonstrates the achievements of the TLOP policy in Sichuan Province.Results show that(1)276 protection zones have been established under the ecological red line,covering key ecosystems and protected areas to ensure environmental security.Under the lower-limit line,1,626 functional(priority,key,and general control)zones have been designated to regulate air,water,and soil quality,enhancing environmental capacity and pollution control.(2)Through the integration and merging of the three lines,1,128 integrated management zones have been established,including 375,625,and 128 priority protection,critical control,and general control zones,respectively.Each zone has its own list of environmental permits to regulate human activities according to different environmental protection and natural resource development regimes.(3)The design of the follow-up assessment index system was informed by regional primary functions and industrial structure.The index system for provinces and cities is structured around three primary indicators—implementation updating,application,and guarantees—and 15 secondary indicators.The system for critical control zones is structured around environmental access,management,and effectiveness and 14 secondary indicators.A stringent environmental zoning system has been established through the TLOP policy,thereby safeguarding environmental security,promoting harmonious existence between humans and nature,and supporting the vision of Beautiful China.展开更多
For high school students in Shanghai, this year's college admission process is a bit different from that in previous years. Locally based Fudan University and Shanghai Jiaotong University (Jiaoda) have been allowe...For high school students in Shanghai, this year's college admission process is a bit different from that in previous years. Locally based Fudan University and Shanghai Jiaotong University (Jiaoda) have been allowed to make some changes in their enrollment procedures. In addition to taking an independently designed entrance展开更多
The National Development and Reform Commission issued the Negative List for Market Access(2025 Edition),which covers rare earth-related areas On April 24,2025,the National Development and Reform Commission(NDRC)issued...The National Development and Reform Commission issued the Negative List for Market Access(2025 Edition),which covers rare earth-related areas On April 24,2025,the National Development and Reform Commission(NDRC)issued the Negative List for Market Access(2025 Edition).Therein,it is specified in the Item 94 from the nineteenth part of the Permit Access Category,the Catalogue of Government Approved Investment Projects(2016 Edition).展开更多
混凝土保护层的抗氯离子渗透性是决定钢筋混凝土结构耐久性的关键因素之一。试验室内测定的混凝土材料的抗氯离子渗透性往往不能真实地反映混凝土保护层的抗氯离子渗透性。Permit Ion Migration Test是目前唯一一种可以现场测定混凝土...混凝土保护层的抗氯离子渗透性是决定钢筋混凝土结构耐久性的关键因素之一。试验室内测定的混凝土材料的抗氯离子渗透性往往不能真实地反映混凝土保护层的抗氯离子渗透性。Permit Ion Migration Test是目前唯一一种可以现场测定混凝土保护层抗氯离子渗透性的试验方法。介绍Permit Ion Migration Test的基本原理和试验方法,推导理论计算公式。通过初步试验介绍了基本试验参数的测定方法并对试验数据的规范化处理提出了建议。展开更多
In this paper, the ability to ignite methane of water-carrying explosives is discussed in detail. The difference of the safety towards methane of water- carrying explosives and ammonite is analysed comparatively. lt i...In this paper, the ability to ignite methane of water-carrying explosives is discussed in detail. The difference of the safety towards methane of water- carrying explosives and ammonite is analysed comparatively. lt is shown that the process of detonation reaction, the duration of fIame by combustible residues of detonation and the fineness of cooling salt in detonation products are important factors of the safety of explosive towards methane. Water-carrying explosives are safer than ammonite used in coal mines.展开更多
Approximately 40% of USA coal originates in an ecologically sensitive area of semi-arid shortgrass prairie in Wyoming. Before a surface coal mine can begin operation in the USA, it must secure a mining permit and comp...Approximately 40% of USA coal originates in an ecologically sensitive area of semi-arid shortgrass prairie in Wyoming. Before a surface coal mine can begin operation in the USA, it must secure a mining permit and comply with regulations and performance standards under the USA Surface Mining Control and Reclamation Act (SMCRA), other federal environmental acts, and state programs. The Wyoming Department of Environmental Quality (WDEQ)/Land Quality Division (LQD) administers Wyoming's coal regulatory program. The permit application and bonding process for the largest surface coal mine permit in the USA, North Antelope Rochelle Mine (NARM) located in short grassland prairie in the northeast Wyoming, is discussed. The permit application process begins with the collection of baseline environ- mental data that characterizes premining conditions of the permit area. The permit application includes adjudication information, baseline information, mine and operation plans, and reclamation plans. Fulfillment of permit commitments and requirements of rules and regulations are inspected monthly by the LQD' s representative in the field. Before a mine permit is issued, the mine operator must submit a reclamation bond to secure the performance of reclamation obligations that is later revised annually. In Wyoming, four reclamation bond release phases indicate the completion of various stages of the reclamatikon process. NARM's specific bond release verification cirteria, performance standards, and field verificatoins of bond release phases are discussed. The Bond Release Geodatabase (a GIS/GPS approach) was developed for this mine to monitor progress in meeting criteria and performance standards for incremental bond release. The Bond Release Geodatabase significantly reduces the time needed to track bond release progress, reach agreement between operator and regulator, and improve the state inspector's ability to assess reclamation adequacy and progress.展开更多
The intensity allocation criteria of carbon emissions permits and its influence on China's regional development are analyzed through the 30-province/autonomous region computable general equilibrium(CGE)model.Simul...The intensity allocation criteria of carbon emissions permits and its influence on China's regional development are analyzed through the 30-province/autonomous region computable general equilibrium(CGE)model.Simulation results show that:industrial intensity criteria without taking regional economic development into account deepen the unbalance of regional economic development;regional intensity criteria without taking industrial properties into account exert little negative impact on regional harmonious development,but relatively high negative influence on high-carbon emission industries.The two-step allocation scheme that the central government allocates emissions permits to provincial governments based on regional economic development and then provincial governments allocate emissions permits to emission resources or entities based on industrial properties is a feasible and operable choice.展开更多
基金The National Natural Science Foundation of China(No.51278220)
文摘In order to restrict non-yielding maneuvers of left-turning vehicles,an optimal design of left-lane line extensions is proposed to solve the problem.A field observation was conducted to collect a data set of left-turning vehicles at the beginning of a green phase at two similar intersections(one with a permitted phase and the other with a protected phase).The comparative analysis shows no significant difference in the speed distribution using either a permitted phase or a protected phase,but it reveals that a permitted phase can lead to a larger acceleration when the left-turn vehicles pass through the conflict points.Those indicate the existence of non-yielding maneuvers of left-turn vehicles at signalized intersections with a permitted phase.Optimal designed left-lane line extensions contain two types of segments,circular curves and transition curves,and they are only related to four geometry parameters of an intersection.The proposed method is easy to use and it can offer reference for intersection channelization and traffic organization.
基金Subject construction funding project of Institute for Chemical Drug Control(Grant No.2024HYZX42)in National Institutes for Food and Drug Control,Beijing,China。
文摘Elemental impurities(EIs)in drug products are a specific class of inorganic contaminants that may originate from various sources.These residual impurities provide no therapeutic benefit to patients and,in some cases,may even catalyze the degradation of drug substances.Therefore,their levels in drug products must be controlled within acceptable limits.The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use(ICH)approved the harmonised Guideline for Elemental Impurities(ICH Q3D)on November 12,2014.On January 10,2020,the National Medical Products Administration(NMPA)announced the adoption of the ICH Q3D principles in China.Inductively coupled plasma mass spectrometry(ICP-MS)offers distinct advantages in detecting trace levels of EIs in drug products.Various validation criteria for the analytical procedure of ICP-MS are specified in the pharmacopoeias.This study compared differences in the validation criteria for ICP-MS,highlighting that the criteria adopted in the United States Pharmacopeia(USP)and European Pharmacopoeia(EP)were particularly specific and detailed,thereby facilitating analytical method development for drug quality control.The aim was to provide a useful reference for analysts conducting EI determination using ICP-MS.
文摘Saud Khan,a Pakistani physician,collected his work and residence permits at the Yangpu Government Service Centre in Danzhou City,Hainan Province,on 18 December 2025.Khan had arrived in Hainan three months earlier to participate in a medical training programme at Hainan Western Central Hospital.By the time the programme concluded,he had made up his mind to stay and broaden his professional experience and long-term career prospects in Hainan.
基金supported by the National Natural Science Foundation of China(grant numbers 42171085)and the National Key R&D Program of China(Grant No.2024YFF1307801,2024YFF1307804).
文摘Integrated environmental management is important for sustainable development.Under China’s“Three Lines One Permit”(TLOP)policy,three types of management zones—priority protection,critical control,and general control zones—are established based on the ecological red line,the lower-limit line for environmental quality,and the resource use line.Human activities are regulated through a permit system.Integrated and multifactorial protection of soil,plant,hydrological,and atmospheric elements is promoted at the regional level.A follow-up assessment contributes to the improvement of policy implementation and effectiveness.This study demonstrates the achievements of the TLOP policy in Sichuan Province.Results show that(1)276 protection zones have been established under the ecological red line,covering key ecosystems and protected areas to ensure environmental security.Under the lower-limit line,1,626 functional(priority,key,and general control)zones have been designated to regulate air,water,and soil quality,enhancing environmental capacity and pollution control.(2)Through the integration and merging of the three lines,1,128 integrated management zones have been established,including 375,625,and 128 priority protection,critical control,and general control zones,respectively.Each zone has its own list of environmental permits to regulate human activities according to different environmental protection and natural resource development regimes.(3)The design of the follow-up assessment index system was informed by regional primary functions and industrial structure.The index system for provinces and cities is structured around three primary indicators—implementation updating,application,and guarantees—and 15 secondary indicators.The system for critical control zones is structured around environmental access,management,and effectiveness and 14 secondary indicators.A stringent environmental zoning system has been established through the TLOP policy,thereby safeguarding environmental security,promoting harmonious existence between humans and nature,and supporting the vision of Beautiful China.
文摘For high school students in Shanghai, this year's college admission process is a bit different from that in previous years. Locally based Fudan University and Shanghai Jiaotong University (Jiaoda) have been allowed to make some changes in their enrollment procedures. In addition to taking an independently designed entrance
文摘The National Development and Reform Commission issued the Negative List for Market Access(2025 Edition),which covers rare earth-related areas On April 24,2025,the National Development and Reform Commission(NDRC)issued the Negative List for Market Access(2025 Edition).Therein,it is specified in the Item 94 from the nineteenth part of the Permit Access Category,the Catalogue of Government Approved Investment Projects(2016 Edition).
文摘混凝土保护层的抗氯离子渗透性是决定钢筋混凝土结构耐久性的关键因素之一。试验室内测定的混凝土材料的抗氯离子渗透性往往不能真实地反映混凝土保护层的抗氯离子渗透性。Permit Ion Migration Test是目前唯一一种可以现场测定混凝土保护层抗氯离子渗透性的试验方法。介绍Permit Ion Migration Test的基本原理和试验方法,推导理论计算公式。通过初步试验介绍了基本试验参数的测定方法并对试验数据的规范化处理提出了建议。
文摘In this paper, the ability to ignite methane of water-carrying explosives is discussed in detail. The difference of the safety towards methane of water- carrying explosives and ammonite is analysed comparatively. lt is shown that the process of detonation reaction, the duration of fIame by combustible residues of detonation and the fineness of cooling salt in detonation products are important factors of the safety of explosive towards methane. Water-carrying explosives are safer than ammonite used in coal mines.
文摘Approximately 40% of USA coal originates in an ecologically sensitive area of semi-arid shortgrass prairie in Wyoming. Before a surface coal mine can begin operation in the USA, it must secure a mining permit and comply with regulations and performance standards under the USA Surface Mining Control and Reclamation Act (SMCRA), other federal environmental acts, and state programs. The Wyoming Department of Environmental Quality (WDEQ)/Land Quality Division (LQD) administers Wyoming's coal regulatory program. The permit application and bonding process for the largest surface coal mine permit in the USA, North Antelope Rochelle Mine (NARM) located in short grassland prairie in the northeast Wyoming, is discussed. The permit application process begins with the collection of baseline environ- mental data that characterizes premining conditions of the permit area. The permit application includes adjudication information, baseline information, mine and operation plans, and reclamation plans. Fulfillment of permit commitments and requirements of rules and regulations are inspected monthly by the LQD' s representative in the field. Before a mine permit is issued, the mine operator must submit a reclamation bond to secure the performance of reclamation obligations that is later revised annually. In Wyoming, four reclamation bond release phases indicate the completion of various stages of the reclamatikon process. NARM's specific bond release verification cirteria, performance standards, and field verificatoins of bond release phases are discussed. The Bond Release Geodatabase (a GIS/GPS approach) was developed for this mine to monitor progress in meeting criteria and performance standards for incremental bond release. The Bond Release Geodatabase significantly reduces the time needed to track bond release progress, reach agreement between operator and regulator, and improve the state inspector's ability to assess reclamation adequacy and progress.
基金supported by National Natural Sci- ence Foundation of China(No.71173212,41101556 and 71203215)the President Fund of GUCAS(No Y1510RY00)
文摘The intensity allocation criteria of carbon emissions permits and its influence on China's regional development are analyzed through the 30-province/autonomous region computable general equilibrium(CGE)model.Simulation results show that:industrial intensity criteria without taking regional economic development into account deepen the unbalance of regional economic development;regional intensity criteria without taking industrial properties into account exert little negative impact on regional harmonious development,but relatively high negative influence on high-carbon emission industries.The two-step allocation scheme that the central government allocates emissions permits to provincial governments based on regional economic development and then provincial governments allocate emissions permits to emission resources or entities based on industrial properties is a feasible and operable choice.