Circadian clock genes are crucial for generating and sustaining most rhythmic daily functions in the animal kingdom,which entrain the rhythms of biochemical,physiological,and behavioural processes.To better understand...Circadian clock genes are crucial for generating and sustaining most rhythmic daily functions in the animal kingdom,which entrain the rhythms of biochemical,physiological,and behavioural processes.To better understand the molecular oscillations of the circadian rhythms in darkbarbel catfish(Pelteobagrus vachellii),we isolated and characterized two circadian clock genes in P.vachellii,period 1(per1),and period 3(per3).The circadian clock gene per1 was found to encode a 1428-amino acid polypeptide,including PER-ARNT-SIM(PAS)dimerisation domains,a PAS-associated C-terminal motif(PAC),a short mutable domain(S/M),and a nuclear export signal(NES).The 4902-bp per3 cDNA includes an open reading frame encoding a 1292-amino acid residue polypeptide with a PER-ARNT-SIM(PAS)domain,cytoplasmic localisation domain(CLD),interaction site(TIS),and a nuclear localisation signal(NLS).The per1 and per3 gene was constitutively expressed in all examined tissues.Moreover,per1 expression within a light/dark cycles showed rhythmic expression in the diencephalon,brain,liver and intestine,with the acrophase at 15:15,12:52,7:51 and 12:55,respectively.Daily expression of per3 was rhythmic in the diencephalonbrain,liver and intestine,with the acrophase at 8:15,9:54,10:39,and 10:25 h,respectively.These findings expand our understanding of circadian mechanism at the molecular level in this species.展开更多
探讨中国人群生物钟Period1(Per1)基因rs2585405、rs2253820和rs2735611位点单核苷酸多态性(single-nucleotide?polymorphisms,SNP)与原发性失眠(primary insomnia,PI)的相关性。方法:采用病例对照研究,选取157例PI者为实验组,并匹配13...探讨中国人群生物钟Period1(Per1)基因rs2585405、rs2253820和rs2735611位点单核苷酸多态性(single-nucleotide?polymorphisms,SNP)与原发性失眠(primary insomnia,PI)的相关性。方法:采用病例对照研究,选取157例PI者为实验组,并匹配133名健康者为对照组。采用MassARRAY SNP 基因分型技术检测Per1基因rs2585405、rs2253820和rs2735611位点多态性。结果:①Per1基因rs2585405、rs2253820和rs2735611位点多态性在PI和对照组的基因型分布均符合Hardy-Weinberg平衡(P>0.05)。②PI组和对照组Per1基因3个SNP位点的基因型和等位基因频率比较,均没有显著性差异(P>0.05)。③PI组和对照组Per1基因3个SNP位点进行单倍型分析,显示构建的3种单倍型之间均没有显著差异(p>0.05)。结论:我们选择标记的Per1基因3个SNP位点可能不是中国人群PI的易感位点。展开更多
Effects of space velocity, reaction temperature and support acidity on product distribution and induction period in 1-butene isomerization and metathesis over Mo/mordenite-alumina were investigated. As revealed by the...Effects of space velocity, reaction temperature and support acidity on product distribution and induction period in 1-butene isomerization and metathesis over Mo/mordenite-alumina were investigated. As revealed by the catalytic performance results, induction period and objective product were closely related to the reaction conditions. Lower space velocity led to longer induction period and higher propene yield. The optimal reaction temperature for propene production is around 150 ~C and it shifted to 100 ~C for ethene production. 1-Butene auto-metathesis predominated in the reaction network if the support with lower degree of sodium exchanged. And propene gradually became the dominant product upon increasing the support sodium exchange degree. 6Mo/H100Na0M-30A1 catalyst with a support of full sodium exchange degree exhibited the highest propene yield.展开更多
In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are...In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are expressed by Jacobi elliptic functions, and obtain some new solitary wave solutions （m → 1）. This method can also be used to explore new periodic wave solutions for other nonlinear evolution equations.展开更多
in this paper, 4N-HCLAIA method was adopted to conduct digestive tests in young female and male Dongtian F1 red deer (Cervus elaphus) of rearing seperatefy in growth period and mixed raising in weaning period in Harbi...in this paper, 4N-HCLAIA method was adopted to conduct digestive tests in young female and male Dongtian F1 red deer (Cervus elaphus) of rearing seperatefy in growth period and mixed raising in weaning period in Harbin Specialty Research Institute. Results indicated that digestive rate of crude protein and crude fiber were 95.35% and 73.68% respectively when rational protein content was 26.8% in growth period. Digestive rate was not significantly different between female and male(P>0.05)i During weaning period, When rational crude protein content is 22.06%, digestive rate of crude protein and crude fiber were 93.05% and 63.96%, respectively. The tests suggest that higher rational protein can be effective in accelerating groWth of young Dongtian F1 red deer during growth period and weaning period(before 10 months old).展开更多
The consistent tanh expansion(CTE) method is employed to the(2+1)-dimensional Caudrey–Dodd–Gibbon–Kotera–Sawada(CDGKS) equation. The interaction solutions between solitons and the cnoidal periodic waves are explic...The consistent tanh expansion(CTE) method is employed to the(2+1)-dimensional Caudrey–Dodd–Gibbon–Kotera–Sawada(CDGKS) equation. The interaction solutions between solitons and the cnoidal periodic waves are explicitly obtained. Concretely, we discuss a special kind of interaction solution in the form of tanh functions and Jacobian elliptic functions in both analytical and graphical ways. The results show that the profiles of the soliton-cnoidal periodic wave interaction solutions can be designed by choosing different values of wave parameters.展开更多
In this paper, we investigate the periodic wave solutions and solitary wave solutions of a (2+1)-dimensional Korteweg-de Vries (KDV) equation</span><span style="font-size:10pt;font-family:"">...In this paper, we investigate the periodic wave solutions and solitary wave solutions of a (2+1)-dimensional Korteweg-de Vries (KDV) equation</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">by applying Jacobi elliptic function expansion method. Abundant types of Jacobi elliptic function solutions are obtained by choosing different </span><span style="font-size:10.0pt;font-family:"">coefficient</span><span style="font-size:10.0pt;font-family:"">s</span><span style="font-size:10pt;font-family:""> <i>p</i>, <i>q</i> and <i>r</i> in the</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">elliptic equation. Then these solutions are</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">coupled into an auxiliary equation</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">and substituted into the (2+1)-dimensional KDV equation. As <span>a result,</span></span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">a large number of complex Jacobi elliptic function solutions are ob</span><span style="font-size:10pt;font-family:"">tained, and many of them have not been found in other documents. As</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10.0pt;font-family:""><span></span></span><span style="font-size:10pt;font-family:"">, some complex solitary solutions are also obtained correspondingly.</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">These solutions that we obtained in this paper will be helpful to understand the physics of the (2+1)-dimensional KDV equation.展开更多
The (2 + 1)-dimensional fifth-order KdV equation is an important higher-dimensional and higher-order extension of the famous KdV equation in fluid dynamics. In this paper, by constructing new test functions, we invest...The (2 + 1)-dimensional fifth-order KdV equation is an important higher-dimensional and higher-order extension of the famous KdV equation in fluid dynamics. In this paper, by constructing new test functions, we investigate the periodic solitary wave solutions for the (2 + 1)-dimensional fifth-order KdV equation by virtue of the Hirota bilinear form. Several novel analytic solutions for such a model are obtained and verified with the help of symbolic computation.展开更多
基金Supported by the National Natural Science Foundation of China(No.31402305)the Sichuan Science and Technology Program(Nos.2017JY0161,2018NZ0119)。
文摘Circadian clock genes are crucial for generating and sustaining most rhythmic daily functions in the animal kingdom,which entrain the rhythms of biochemical,physiological,and behavioural processes.To better understand the molecular oscillations of the circadian rhythms in darkbarbel catfish(Pelteobagrus vachellii),we isolated and characterized two circadian clock genes in P.vachellii,period 1(per1),and period 3(per3).The circadian clock gene per1 was found to encode a 1428-amino acid polypeptide,including PER-ARNT-SIM(PAS)dimerisation domains,a PAS-associated C-terminal motif(PAC),a short mutable domain(S/M),and a nuclear export signal(NES).The 4902-bp per3 cDNA includes an open reading frame encoding a 1292-amino acid residue polypeptide with a PER-ARNT-SIM(PAS)domain,cytoplasmic localisation domain(CLD),interaction site(TIS),and a nuclear localisation signal(NLS).The per1 and per3 gene was constitutively expressed in all examined tissues.Moreover,per1 expression within a light/dark cycles showed rhythmic expression in the diencephalon,brain,liver and intestine,with the acrophase at 15:15,12:52,7:51 and 12:55,respectively.Daily expression of per3 was rhythmic in the diencephalonbrain,liver and intestine,with the acrophase at 8:15,9:54,10:39,and 10:25 h,respectively.These findings expand our understanding of circadian mechanism at the molecular level in this species.
文摘探讨中国人群生物钟Period1(Per1)基因rs2585405、rs2253820和rs2735611位点单核苷酸多态性(single-nucleotide?polymorphisms,SNP)与原发性失眠(primary insomnia,PI)的相关性。方法:采用病例对照研究,选取157例PI者为实验组,并匹配133名健康者为对照组。采用MassARRAY SNP 基因分型技术检测Per1基因rs2585405、rs2253820和rs2735611位点多态性。结果:①Per1基因rs2585405、rs2253820和rs2735611位点多态性在PI和对照组的基因型分布均符合Hardy-Weinberg平衡(P>0.05)。②PI组和对照组Per1基因3个SNP位点的基因型和等位基因频率比较,均没有显著性差异(P>0.05)。③PI组和对照组Per1基因3个SNP位点进行单倍型分析,显示构建的3种单倍型之间均没有显著差异(p>0.05)。结论:我们选择标记的Per1基因3个SNP位点可能不是中国人群PI的易感位点。
基金the National Natural Science Foundation of China(Grant No.20903088 and 21006104)
文摘Effects of space velocity, reaction temperature and support acidity on product distribution and induction period in 1-butene isomerization and metathesis over Mo/mordenite-alumina were investigated. As revealed by the catalytic performance results, induction period and objective product were closely related to the reaction conditions. Lower space velocity led to longer induction period and higher propene yield. The optimal reaction temperature for propene production is around 150 ~C and it shifted to 100 ~C for ethene production. 1-Butene auto-metathesis predominated in the reaction network if the support with lower degree of sodium exchanged. And propene gradually became the dominant product upon increasing the support sodium exchange degree. 6Mo/H100Na0M-30A1 catalyst with a support of full sodium exchange degree exhibited the highest propene yield.
基金Project supported by the Anhui Key Laboratory of Information Materials and Devices (Anhui University),China
文摘In this paper, we make use of the auxiliary equation and the expanded mapping methods to find the new exact periodic solutions for （2＋1）-dimensional dispersive long wave equations in mathematical physics, which are expressed by Jacobi elliptic functions, and obtain some new solitary wave solutions （m → 1）. This method can also be used to explore new periodic wave solutions for other nonlinear evolution equations.
文摘in this paper, 4N-HCLAIA method was adopted to conduct digestive tests in young female and male Dongtian F1 red deer (Cervus elaphus) of rearing seperatefy in growth period and mixed raising in weaning period in Harbin Specialty Research Institute. Results indicated that digestive rate of crude protein and crude fiber were 95.35% and 73.68% respectively when rational protein content was 26.8% in growth period. Digestive rate was not significantly different between female and male(P>0.05)i During weaning period, When rational crude protein content is 22.06%, digestive rate of crude protein and crude fiber were 93.05% and 63.96%, respectively. The tests suggest that higher rational protein can be effective in accelerating groWth of young Dongtian F1 red deer during growth period and weaning period(before 10 months old).
基金Supported by the National Natural Science Foundation of China under Grant No.11505154the Zhejiang Provincial Natural Science Foundation of China under Grant No.LQ16A010003the Scientific Research Foundation for Doctoral Program of Zhejiang Ocean University under Grant No.Q1511
文摘The consistent tanh expansion(CTE) method is employed to the(2+1)-dimensional Caudrey–Dodd–Gibbon–Kotera–Sawada(CDGKS) equation. The interaction solutions between solitons and the cnoidal periodic waves are explicitly obtained. Concretely, we discuss a special kind of interaction solution in the form of tanh functions and Jacobian elliptic functions in both analytical and graphical ways. The results show that the profiles of the soliton-cnoidal periodic wave interaction solutions can be designed by choosing different values of wave parameters.
文摘In this paper, we investigate the periodic wave solutions and solitary wave solutions of a (2+1)-dimensional Korteweg-de Vries (KDV) equation</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">by applying Jacobi elliptic function expansion method. Abundant types of Jacobi elliptic function solutions are obtained by choosing different </span><span style="font-size:10.0pt;font-family:"">coefficient</span><span style="font-size:10.0pt;font-family:"">s</span><span style="font-size:10pt;font-family:""> <i>p</i>, <i>q</i> and <i>r</i> in the</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">elliptic equation. Then these solutions are</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">coupled into an auxiliary equation</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">and substituted into the (2+1)-dimensional KDV equation. As <span>a result,</span></span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">a large number of complex Jacobi elliptic function solutions are ob</span><span style="font-size:10pt;font-family:"">tained, and many of them have not been found in other documents. As</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10.0pt;font-family:""><span></span></span><span style="font-size:10pt;font-family:"">, some complex solitary solutions are also obtained correspondingly.</span><span style="font-size:10pt;font-family:""> </span><span style="font-size:10pt;font-family:"">These solutions that we obtained in this paper will be helpful to understand the physics of the (2+1)-dimensional KDV equation.
文摘The (2 + 1)-dimensional fifth-order KdV equation is an important higher-dimensional and higher-order extension of the famous KdV equation in fluid dynamics. In this paper, by constructing new test functions, we investigate the periodic solitary wave solutions for the (2 + 1)-dimensional fifth-order KdV equation by virtue of the Hirota bilinear form. Several novel analytic solutions for such a model are obtained and verified with the help of symbolic computation.
