Background This study was aimed to evaluate the stigma and quality of life(QoL)in adult patients with epilepsy(PWEs)and explore the relationship between stigma and QoL.Methods Two hundred and ninety-eight PWEs admitte...Background This study was aimed to evaluate the stigma and quality of life(QoL)in adult patients with epilepsy(PWEs)and explore the relationship between stigma and QoL.Methods Two hundred and ninety-eight PWEs admitted to the Epilepsy Center of the First Affiliated Hospitalof Chongqing Medical University during September 2020 and March 2021 were enrolled in this study.All participantscompleted self-reported questionnaires including the Stigma Scale for Epilepsy and the Quality of Life in EpilepsyInventory-31(QOLIE-31).Results A total of 146(49%)PWEs reported an experience of stigma.The total score of QOLIE-31 and the individualscores of seven subscales(worry about new seizures,emotion,well-being,energy and fatigue,cognitive impairment,medication effect,and social function)were significantly decreased in these patients(P<0.001).Multivariate stepwiselinear regression analysis showed that the annual household income per capita,the number of antiseizure medica-tions and stigma had statistically significant effects on QoL(P<0.05).Among them,stigma had the most significantnegative effect.Conclusions Nearly half of PWEs have experienced stigma.Stigma,lower household income per capita,and polyp-harmacy treatment are associated with poorer QoL.Stigma has the most obvious negative impact.展开更多
基金supported by the National Natural Science Foundation of China project(81471320).
文摘Background This study was aimed to evaluate the stigma and quality of life(QoL)in adult patients with epilepsy(PWEs)and explore the relationship between stigma and QoL.Methods Two hundred and ninety-eight PWEs admitted to the Epilepsy Center of the First Affiliated Hospitalof Chongqing Medical University during September 2020 and March 2021 were enrolled in this study.All participantscompleted self-reported questionnaires including the Stigma Scale for Epilepsy and the Quality of Life in EpilepsyInventory-31(QOLIE-31).Results A total of 146(49%)PWEs reported an experience of stigma.The total score of QOLIE-31 and the individualscores of seven subscales(worry about new seizures,emotion,well-being,energy and fatigue,cognitive impairment,medication effect,and social function)were significantly decreased in these patients(P<0.001).Multivariate stepwiselinear regression analysis showed that the annual household income per capita,the number of antiseizure medica-tions and stigma had statistically significant effects on QoL(P<0.05).Among them,stigma had the most significantnegative effect.Conclusions Nearly half of PWEs have experienced stigma.Stigma,lower household income per capita,and polyp-harmacy treatment are associated with poorer QoL.Stigma has the most obvious negative impact.
