Dear Editor,The Enterobacterales are an order of Gram-negative bacteria comprising a few major human pathogens such as Escherichia coli and Klebsiella pneumoniae.However,carbapenem-resistant Enterobacterales(CRE)has r...Dear Editor,The Enterobacterales are an order of Gram-negative bacteria comprising a few major human pathogens such as Escherichia coli and Klebsiella pneumoniae.However,carbapenem-resistant Enterobacterales(CRE)has risen as an urgent threat for human health,leading to high mortality with very limited antimicrobial options.The main mechanism mediating resistance to βlactams including carbapenems in the Enterobacterales is production of β-lactamases,which are two categories of enzymes capable of hydrolyzing β-lactams:serine β-lactamases and metallo β-lactamases(MBLs).展开更多
Objective To investigate the drug-resistance rate of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014.Methods A total of 860 strains(S.pneumoniae 299,K.pneum...Objective To investigate the drug-resistance rate of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014.Methods A total of 860 strains(S.pneumoniae 299,K.pneumoniae 221,H.influenzae 185,S.aureus 116。展开更多
Objective To investigate the detection rate of intestinal colonization of carbapenem-resistant Enterobacterales(CRE) in inpatients, and to analyze the molecular epidemiological characteristics of CRE strains.Methods T...Objective To investigate the detection rate of intestinal colonization of carbapenem-resistant Enterobacterales(CRE) in inpatients, and to analyze the molecular epidemiological characteristics of CRE strains.Methods This was a prospective study.展开更多
基金supported by the National Natural Science Foundation of China(Grants No.82172309 and 81861138055)the 1.3.5 Project for Disciplines of Excellence from West China Hospital of Sichuan University(Grant No.ZYGD22001).
文摘Dear Editor,The Enterobacterales are an order of Gram-negative bacteria comprising a few major human pathogens such as Escherichia coli and Klebsiella pneumoniae.However,carbapenem-resistant Enterobacterales(CRE)has risen as an urgent threat for human health,leading to high mortality with very limited antimicrobial options.The main mechanism mediating resistance to βlactams including carbapenems in the Enterobacterales is production of β-lactamases,which are two categories of enzymes capable of hydrolyzing β-lactams:serine β-lactamases and metallo β-lactamases(MBLs).
文摘Objective To investigate the drug-resistance rate of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014.Methods A total of 860 strains(S.pneumoniae 299,K.pneumoniae 221,H.influenzae 185,S.aureus 116。
文摘Objective To investigate the detection rate of intestinal colonization of carbapenem-resistant Enterobacterales(CRE) in inpatients, and to analyze the molecular epidemiological characteristics of CRE strains.Methods This was a prospective study.
