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Parvalbumin and Somatostatin Neurons in the Thalamic Reticular Nucleus Modulate Visual Information Processing in V1 of Mouse
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作者 Jiamin Bu Guangwei Xu Yifeng Zhou 《Neuroscience Bulletin》 2025年第10期1824-1842,共19页
The thalamic reticular nucleus(TRN)plays a crucial role in regulating sensory encoding,even at the earliest stages of visual processing,as evidenced by numerous studies.Orientation selectivity,a vital neural response,... The thalamic reticular nucleus(TRN)plays a crucial role in regulating sensory encoding,even at the earliest stages of visual processing,as evidenced by numerous studies.Orientation selectivity,a vital neural response,is essential for detecting objects through edge perception.Here,we demonstrate that somatostatin(SOM)-expressing and parvalbumin(PV)-expressing neurons in the TRN project to the dorsal lateral geniculate nucleus and modulate orientation selectivity and the capacity for visual information processing in the primary visual cortex(V1).These findings show that SOM-positive and PV-positive neurons in the TRN are powerful modulators of visual information encoding in V1,revealing a novel role for this thalamic nucleus in influencing visual processing. 展开更多
关键词 Thalamic reticular nucleus parvalbuminpositive neurons Somatostatin-positive neurons Primary visual cortex Dorsal lateral geniculate nuclei Receptive feld properties
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