Panvascular diseases(PVD)are a group of systemic disorders characterized by vascular pathologies,posing a significant threat to human health.Traditional risk factors for PVD include advanced age,male gender,hypertensi...Panvascular diseases(PVD)are a group of systemic disorders characterized by vascular pathologies,posing a significant threat to human health.Traditional risk factors for PVD include advanced age,male gender,hypertension,diabetes mellitus,dyslipidemia,hyperuricemia,smoking,and excessive alcohol consumption.Emerging risk factors encompass chronic inflammatory diseases,Helicobacter pylori infection,air pollution,sleep disorders,and psychological stress.These factors interact synergistically,accelerating vascular dysfunction and increasing the risk of cardiovascular and cerebrovascular events.This review integrated multidisciplinary knowledge to systematically delineate PVD risk factors,thereby establishing a scientific foundation for precise risk assessment and preventive strategies.Ultimately,these efforts may advance panvascular research,improve patient prognosis,reduce healthcare burdens,and enhance population vascular health.展开更多
In the evolving tapestry of medical science,the traditional boundaries between disciplines are being reimagined,resulting in the rise of innovative paradigms that bridge previously disconnected areas of research.In th...In the evolving tapestry of medical science,the traditional boundaries between disciplines are being reimagined,resulting in the rise of innovative paradigms that bridge previously disconnected areas of research.In the traditional concept of cardio-oncology,cancer treatments are often associated with cardiotoxicity and panvascular system damage.However,recent findings have revealed that some cancer treatments may have therapeutic effects against panvascular diseases(e.g.,coronary heart disease).This has led to the proposal of pancardio-oncology,which is a more holistic concept.展开更多
Panvascular diseases,sharing atherosclerosis as a common pathological basis,pose a significant threat to human health.Flexible fibers combined with sensing elements become implantable and interventional smart fibers w...Panvascular diseases,sharing atherosclerosis as a common pathological basis,pose a significant threat to human health.Flexible fibers combined with sensing elements become implantable and interventional smart fibers with monitoring and intervention capabilities.Due to the prolonged course of panvascular diseases,higher requirements are imposed on the monitoring-intervention closed-loop system of flexible fibers—high suitcordance(a combination of short-term suitability and long-term concordance).Suitcordance implies that novel flexible fibers must meet the traditional concept of compatibility and satisfy the new requirement of long-term co-regulation of fiber-vascular fate.This review introduces emerging flexible fiber electronic devices with exceptional performance related to panvascular diseases.These devices adapt well to the complex panvascular environment and provide ideal technical support for real-time,non-invasive,and continuous health monitoring-treatment.However,existing devices have limitations,and future research should focus on developing novel flexible smart fibers based on the clinical needs of panvascular diseases.展开更多
文摘Panvascular diseases(PVD)are a group of systemic disorders characterized by vascular pathologies,posing a significant threat to human health.Traditional risk factors for PVD include advanced age,male gender,hypertension,diabetes mellitus,dyslipidemia,hyperuricemia,smoking,and excessive alcohol consumption.Emerging risk factors encompass chronic inflammatory diseases,Helicobacter pylori infection,air pollution,sleep disorders,and psychological stress.These factors interact synergistically,accelerating vascular dysfunction and increasing the risk of cardiovascular and cerebrovascular events.This review integrated multidisciplinary knowledge to systematically delineate PVD risk factors,thereby establishing a scientific foundation for precise risk assessment and preventive strategies.Ultimately,these efforts may advance panvascular research,improve patient prognosis,reduce healthcare burdens,and enhance population vascular health.
基金supported by the“Fuqing(Fu Ching)Scholar”Student Scientific Research Program of Shanghai Medical College,Fudan University,China(FQXZ202301A)Project of Basic Science Center of the National Natural Science Foundation of China(T2288101)+1 种基金the National Natural Science Foundation of China(82370261,82470405,82200290,82370513,82470271 and 82300375)China Heart House-Chinese Cardiovascular Association-2024 TCM fund(2024-CCA-TCM-070).
文摘In the evolving tapestry of medical science,the traditional boundaries between disciplines are being reimagined,resulting in the rise of innovative paradigms that bridge previously disconnected areas of research.In the traditional concept of cardio-oncology,cancer treatments are often associated with cardiotoxicity and panvascular system damage.However,recent findings have revealed that some cancer treatments may have therapeutic effects against panvascular diseases(e.g.,coronary heart disease).This has led to the proposal of pancardio-oncology,which is a more holistic concept.
基金supported by the National Natural Science Foundation of China(T2288101,82170342)Medical Engineering Joint Fund of Fudan University(yg2023-01).
文摘Panvascular diseases,sharing atherosclerosis as a common pathological basis,pose a significant threat to human health.Flexible fibers combined with sensing elements become implantable and interventional smart fibers with monitoring and intervention capabilities.Due to the prolonged course of panvascular diseases,higher requirements are imposed on the monitoring-intervention closed-loop system of flexible fibers—high suitcordance(a combination of short-term suitability and long-term concordance).Suitcordance implies that novel flexible fibers must meet the traditional concept of compatibility and satisfy the new requirement of long-term co-regulation of fiber-vascular fate.This review introduces emerging flexible fiber electronic devices with exceptional performance related to panvascular diseases.These devices adapt well to the complex panvascular environment and provide ideal technical support for real-time,non-invasive,and continuous health monitoring-treatment.However,existing devices have limitations,and future research should focus on developing novel flexible smart fibers based on the clinical needs of panvascular diseases.
