Objective:To find out factors related to the delay in diagnosis of panic disorder. Methods: One hundred patients with panic disorder were assessed and investigated with SCL-90 and a self-compiled questionnaire.Linear ...Objective:To find out factors related to the delay in diagnosis of panic disorder. Methods: One hundred patients with panic disorder were assessed and investigated with SCL-90 and a self-compiled questionnaire.Linear regression was applied in the multivariate statistical analysis,with the delayed time (from the age at onset to the age at being definitely diagnosed) as dependent variable and SCL-90 factorial scores, the existing symptoms and the demographic factors as independent variables. Results:Factors negatively correlated with the delayed time were depression ,nausea/abdominal discomfort and fear of dying while those positively correlated with it were phobia and depersonalization/derealization. Conclusion: Depression may contribute to early diagnosis of panic disorder.展开更多
目的综合评价惊恐障碍与外周血脑源性神经营养因子(BDNF)水平的相关性,探索该类患者外周血BDNF水平特点及相关因素。方法计算机检索ISI Web of science,Embase,Pubmed和中国期刊网(CNKI)、万方数据资源系统、中国科技期刊数据库(维普数...目的综合评价惊恐障碍与外周血脑源性神经营养因子(BDNF)水平的相关性,探索该类患者外周血BDNF水平特点及相关因素。方法计算机检索ISI Web of science,Embase,Pubmed和中国期刊网(CNKI)、万方数据资源系统、中国科技期刊数据库(维普数据库),并辅以文献追溯方法,收集1980年1月～2010年8月国内外公开发表的关于惊恐障碍患者外周血BDNF水平的研究文献,采用Revman5.0软件进行Meta分析。结果共纳入3篇文献,累计299名被试者。由于文献数量较少且存在明显的异质性(I2=96%),不进行Meta分析,故仅就文献内容进行了描述。结论目前关于惊恐障碍患者外周血BDNF水平的研究数量尚少。各研究之间结果差异甚大,且在已有研究中存在信息不明确、报告不标准和不全面等问题,需采用公认的测量方法和全面报告结果的准则,进行大样本、前瞻性对照研究。展开更多
文摘Objective:To find out factors related to the delay in diagnosis of panic disorder. Methods: One hundred patients with panic disorder were assessed and investigated with SCL-90 and a self-compiled questionnaire.Linear regression was applied in the multivariate statistical analysis,with the delayed time (from the age at onset to the age at being definitely diagnosed) as dependent variable and SCL-90 factorial scores, the existing symptoms and the demographic factors as independent variables. Results:Factors negatively correlated with the delayed time were depression ,nausea/abdominal discomfort and fear of dying while those positively correlated with it were phobia and depersonalization/derealization. Conclusion: Depression may contribute to early diagnosis of panic disorder.
文摘目的综合评价惊恐障碍与外周血脑源性神经营养因子(BDNF)水平的相关性,探索该类患者外周血BDNF水平特点及相关因素。方法计算机检索ISI Web of science,Embase,Pubmed和中国期刊网(CNKI)、万方数据资源系统、中国科技期刊数据库(维普数据库),并辅以文献追溯方法,收集1980年1月～2010年8月国内外公开发表的关于惊恐障碍患者外周血BDNF水平的研究文献,采用Revman5.0软件进行Meta分析。结果共纳入3篇文献,累计299名被试者。由于文献数量较少且存在明显的异质性(I2=96%),不进行Meta分析,故仅就文献内容进行了描述。结论目前关于惊恐障碍患者外周血BDNF水平的研究数量尚少。各研究之间结果差异甚大,且在已有研究中存在信息不明确、报告不标准和不全面等问题,需采用公认的测量方法和全面报告结果的准则,进行大样本、前瞻性对照研究。
