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In Vitro Evaluation of the Physicochemical Compatibility of Four Perfusion Mixtures: Case of an Ampoule of Paluject® in Glucose Serum with/or without Vogalene®
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作者 Alphonse Rodrigue Djiboune Papa Mady Sy +6 位作者 Abdou Faye Mamadou Soumboundou Sidy Mouhamed Dieng Mariama Dianké Diédhiou Louis Augustin Diaga Diouf Gora Mbaye Mounibé Diarra 《Journal of Modern Physics》 2024年第13期2398-2406,共9页
In this study, the physicochemical compatibility and stability of four drug mixtures were evaluated, and the common drug mixtures used in the treatment of severe malaria in children were simulated by gravity perfusion... In this study, the physicochemical compatibility and stability of four drug mixtures were evaluated, and the common drug mixtures used in the treatment of severe malaria in children were simulated by gravity perfusion dynamic simulation experiment. The results showed that under experimental conditions, all drug mixtures exhibited clear transparency, stable density and refractive index, and pH values changed by no more than one unit, demonstrating compatibility and stability during the study period. 展开更多
关键词 Physicochemical Compatibility and Stability PERFUSION paluject® Glucose Serum Vogalene®
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青蒿琥酯和巴利捷克治疗脑型疟病儿的对比研究
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作者 吴小挺 缪影玲 《河北医学》 CAS 1998年第8期10-11,共2页
目的:比较青蒿琥酯和巴利捷克治疗塞内加尔脑型疟病儿的疗效。方法:青蒿琥酯组120例(男76例,女44例;年龄6.9±3.1岁),剂量每次1.5mg/kg,iv或im,于入院后即刻,h4、h24、h48和h72给药... 目的:比较青蒿琥酯和巴利捷克治疗塞内加尔脑型疟病儿的疗效。方法:青蒿琥酯组120例(男76例,女44例;年龄6.9±3.1岁),剂量每次1.5mg/kg,iv或im,于入院后即刻,h4、h24、h48和h72给药;巴利捷克组120例(男73例,女47例;年龄6.8±3.0岁),剂量25mg奎宁基质/(kg·d),iv或im,bid,3d为一个疗程。结果:青蒿琥酯组较巴利捷克组治愈率高(P<0.01),治愈病儿昏迷清醒时间、退热时间、血疟原虫转阴时间和住院时间皆短(P均<0.01)。结论:青蒿琥酯治疗脑型疟病儿疗效优于巴利捷克。 展开更多
关键词 青蒿琥酯 巴利捷克 脑型 疟疾 儿童
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青蒿琥酯和巴利捷克治疗塞内加尔恶性疟病儿的比较 被引量:6
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作者 吴小挺 兰雅恭 《新药与临床》 CSCD 北大核心 1995年第6期373-374,共2页
目的:比较青蒿琥酯和巴利捷克治疗西非塞内加尔恶性疟的疗效。方法:西非恶性疟病儿190例,随机分为青蒿琥酯组76例(男性47例,女性29例,年龄6±s3a),用青蒿琥酯每次15mg/kg,iv或1m,于入院后即刻,... 目的:比较青蒿琥酯和巴利捷克治疗西非塞内加尔恶性疟的疗效。方法:西非恶性疟病儿190例,随机分为青蒿琥酯组76例(男性47例,女性29例,年龄6±s3a),用青蒿琥酯每次15mg/kg,iv或1m,于入院后即刻,h4,h24,h48给药,2d为一个疗程;巴利捷克组114例(男性68例,女性46例;年龄6±3a),用巴利捷克剂量25mg奎宁基质/(kg·d),iv或im,bid,3d为一个疗程。结果2组血检疟原虫转阴率,退热时间和住院时间各为94.7%,78.9%;1.3±0.5d,2.7±1.1d和3.2±1.1d,4.5±1.5d;差别皆有非常显著意义(P均<0.01)。结论:青蒿琥酯疗效优于巴利捷克。 展开更多
关键词 青蒿琥酯 巴利捷克 疟原虫 治疗 疟疾
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